Christian Winkler - Publications

Affiliations: 
Neurology University of Freiburg, Germany, Freiburg im Breisgau, Baden-Württemberg, Germany 
Area:
Cell transplantation

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Antonini A, Poewe W, Chaudhuri KR, Jech R, Pickut B, Pirtošek Z, Szasz J, Valldeoriola F, Winkler C, Bergmann L, Yegin A, Onuk K, Barch D, Odin P. Levodopa-carbidopa intestinal gel in advanced Parkinson's: Final results of the GLORIA registry. Parkinsonism & Related Disorders. PMID 29037498 DOI: 10.1016/j.parkreldis.2017.09.018  0.4
2017 Winkler C, Reis J, Hoffmann N, Gellner AK, Münkel C, Curado MR, Furlanetti L, Garcia J, Döbrössy MD, Fritsch B. Anodal Transcranial Direct Current Stimulation Enhances Survival and Integration of Dopaminergic Cell Transplants in a Rat Parkinson Model. Eneuro. 4. PMID 28966974 DOI: 10.1523/ENEURO.0063-17.2017  0.88
2015 Krüger R, Hilker R, Winkler C, Lorrain M, Hahne M, Redecker C, Lingor P, Jost WH. Advanced stages of PD: interventional therapies and related patient-centered care. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 26138439 DOI: 10.1007/s00702-015-1418-0  0.96
2015 Furlanetti LL, Cordeiro JG, Cordeiro KK, García JA, Winkler C, Lepski GA, Coenen VA, Nikkhah G, Döbrössy MD. Continuous High-Frequency Stimulation of the Subthalamic Nucleus Improves Cell Survival and Functional Recovery Following Dopaminergic Cell Transplantation in Rodents. Neurorehabilitation and Neural Repair. PMID 25857428 DOI: 10.1177/1545968315581419  0.96
2014 Amtage F, Maurer C, Hellwig S, Tüscher O, Kreft A, Weiller C, Rijntjes M, Winkler C, Meyer PT. Functional correlates of vertical gaze palsy and other ocular motor deficits in PSP: an FDG-PET study. Parkinsonism & Related Disorders. 20: 898-906. PMID 24935235 DOI: 10.1016/j.parkreldis.2014.05.013  0.96
2014 Cordeiro KK, Cordeiro JG, Furlanetti LL, Garcia Salazar JA, Tenório SB, Winkler C, Döbrössy MD, Nikkhah G. Subthalamic nucleus lesion improves cell survival and functional recovery following dopaminergic cell transplantation in parkinsonian rats. The European Journal of Neuroscience. 39: 1474-84. PMID 24628951 DOI: 10.1111/ejn.12541  0.96
2014 Amtage F, Hellwig S, Kreft A, Spehl T, Glauche V, Winkler C, Rijntjes M, Hellwig B, Weiller C, Weber WA, Tüscher O, Meyer PT. Neuronal correlates of clinical asymmetry in progressive supranuclear palsy. Clinical Nuclear Medicine. 39: 319-25. PMID 24566396 DOI: 10.1097/RLU.0000000000000373  0.96
2014 Piroth T, Pauly MC, Schneider C, Wittmer A, Möllers S, Döbrössy M, Winkler C, Nikkhah G. Transplantation of human fetal tissue for neurodegenerative diseases: validation of a new protocol for microbiological analysis and bacterial decontamination. Cell Transplantation. 23: 995-1007. PMID 23635602 DOI: 10.3727/096368913X666449  0.96
2013 Pauly MC, Döbrössy MD, Nikkhah G, Winkler C, Piroth T. Organization of the human fetal subpallium. Frontiers in Neuroanatomy. 7: 54. PMID 24474906 DOI: 10.3389/fnana.2013.00054  0.96
2013 Jost W, Südmeyer M, Winkler C. Continuous intestinal administration of levodopa and B vitamins: What to take heed of? | Kontinuierliche intestinale L-Dopa-Gabe und B-Vitamine: was ist zu beachten? Aktuelle Neurologie. 40: 343-345. DOI: 10.1055/s-0033-1347251  0.96
2013 Csoti I, Fogel W, Schade S, Schnitzler A, Südmeyer M, Winkler C, Winkler J. Pain in parkinson's disease | Schmerz bei Parkinson-Patienten Aktuelle Neurologie. 40: 321-326. DOI: 10.1055/s-0033-1343339  0.96
2012 Lane EL, Winkler C. L-DOPA- and graft-induced dyskinesia following transplantation. Progress in Brain Research. 200: 143-68. PMID 23195418 DOI: 10.1016/B978-0-444-59575-1.00007-7  0.96
2012 Hellwig S, Amtage F, Kreft A, Buchert R, Winz OH, Vach W, Spehl TS, Rijntjes M, Hellwig B, Weiller C, Winkler C, Weber WA, Tüscher O, Meyer PT. [¹⁸F]FDG-PET is superior to [¹²³I]IBZM-SPECT for the differential diagnosis of parkinsonism. Neurology. 79: 1314-22. PMID 22914831 DOI: 10.1212/WNL.0b013e31826c1b0a  0.96
2012 Amtage F, Spehl TS, Hellwig S, Sahm U, Hellwig B, Reuland P, Weiller C, Weber WA, Winkler C, Meyer PT. Assessment of striatal dopamine D2/D3 receptor availability with PET and 18F-desmethoxyfallypride: comparison of imaging protocols suited for clinical routine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1558-64. PMID 22899645 DOI: 10.2967/jnumed.112.103812  0.96
2012 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Impact of dopamine versus serotonin cell transplantation for the development of graft-induced dyskinesia in a rat Parkinson model. Brain Research. 1470: 119-29. PMID 22759908 DOI: 10.1016/j.brainres.2012.06.029  0.96
2012 Stich O, Nagy S, Reinhard M, Hetzel A, Winkler C, Taschner C, Leschka SC, Weiller C, Rijntjes M. Hypoglossal nerve palsy after extensive vomiting. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 744, 776-7. PMID 22616107 DOI: 10.1016/j.jocn.2011.04.013  0.96
2012 Shin E, Garcia J, Winkler C, Björklund A, Carta M. Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease. Neurobiology of Disease. 47: 393-406. PMID 22579773 DOI: 10.1016/j.nbd.2012.03.038  0.96
2012 Kaindlstorfer C, García J, Winkler C, Wenning GK, Nikkhah G, Döbrössy MD. Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy. Journal of Neuroscience Research. 90: 1284-95. PMID 22488729 DOI: 10.1002/jnr.23021  0.96
2012 Winkler C. The timing of continuous dopaminergic stimulation for optimal clinical outcomes European Neurological Review. 7: 20-26.  0.96
2011 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation. Experimental Neurology. 232: 270-9. PMID 21946270 DOI: 10.1016/j.expneurol.2011.09.017  0.96
2011 Rochlitzer S, Veres TZ, Kühne K, Prenzler F, Pilzner C, Knothe S, Winkler C, Lauenstein HD, Willart M, Hammad H, Müller M, Krug N, Lambrecht BN, Braun A. The neuropeptide calcitonin gene-related peptide affects allergic airway inflammation by modulating dendritic cell function. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 41: 1609-21. PMID 21752117 DOI: 10.1111/j.1365-2222.2011.03822.x  0.96
2011 Seehase S, Schlepütz M, Switalla S, Mätz-Rensing K, Kaup FJ, Zöller M, Schlumbohm C, Fuchs E, Lauenstein HD, Winkler C, Kuehl AR, Uhlig S, Braun A, Sewald K, Martin C. Bronchoconstriction in nonhuman primates: a species comparison. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 791-8. PMID 21700889 DOI: 10.1152/japplphysiol.00162.2011  0.96
2011 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Impact of dopamine to serotonin cell ratio in transplants on behavioral recovery and L-DOPA-induced dyskinesia. Neurobiology of Disease. 43: 576-87. PMID 21600983 DOI: 10.1016/j.nbd.2011.05.004  0.96
2011 Capetian P, Döbrössy M, Winkler C, Prinz M, Nikkhah G. To be or not to be accepted: the role of immunogenicity of neural stem cells following transplantation into the brain in animal and human studies. Seminars in Immunopathology. 33: 619-26. PMID 21533909 DOI: 10.1007/s00281-011-0272-x  0.96
2010 Lane EL, Björklund A, Dunnett SB, Winkler C. Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia. Progress in Brain Research. 184: 295-309. PMID 20887881 DOI: 10.1016/S0079-6123(10)84015-4  0.96
2009 Carlsson T, Carta M, Muñoz A, Mattsson B, Winkler C, Kirik D, Björklund A. Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration. Brain : a Journal of Neurology. 132: 319-35. PMID 19039008 DOI: 10.1093/brain/awn305  0.96
2007 Carlsson T, Carta M, Winkler C, Björklund A, Kirik D. Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8011-22. PMID 17652591 DOI: 10.1523/JNEUROSCI.2079-07.2007  0.96
2007 Breysse N, Carlsson T, Winkler C, Björklund A, Kirik D. The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5849-56. PMID 17537955 DOI: 10.1523/JNEUROSCI.0626-07.2007  0.96
2007 Timmer M, Cesnulevicius K, Winkler C, Kolb J, Lipokatic-Takacs E, Jungnickel J, Grothe C. Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 459-71. PMID 17234579 DOI: 10.1523/JNEUROSCI.4493-06.2007  0.96
2006 Winkler C, Georgievska B, Carlsson T, Lacar B, Kirik D. Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats. Neuroscience. 141: 521-31. PMID 16697115 DOI: 10.1016/j.neuroscience.2006.03.068  0.96
2006 Winkler C, Gil JM, Araújo IM, Riess O, Skripuletz T, von Hörsten S, Petersén A. Normal sensitivity to excitotoxicity in a transgenic Huntington's disease rat. Brain Research Bulletin. 69: 306-10. PMID 16564426 DOI: 10.1016/j.brainresbull.2006.01.003  0.96
2006 Lane EL, Winkler C, Brundin P, Cenci MA. The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat. Neurobiology of Disease. 22: 334-45. PMID 16406222 DOI: 10.1016/j.nbd.2005.11.011  0.96
2006 Carlsson T, Winkler C, Lundblad M, Cenci MA, Björklund A, Kirik D. Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiology of Disease. 21: 657-68. PMID 16256359 DOI: 10.1016/j.nbd.2005.09.008  0.96
2006 Roy M, Winkler C, Holtz M, Te Wildt B, Becker J, Emrich HM, Ohlmeier MD. Diagnosis: Wernicke encephalopathy in a patient with oculo-cutaneous albinism | Diagnose: Wernicke-enzephalopathie bei okulokutanem albinismus Aktuelle Neurologie. 33: 497-499. DOI: 10.1055/s-2006-932588  0.96
2005 Puschban Z, Stefanova N, Petersén A, Winkler C, Brundin P, Poewe W, Wenning GK. Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy. Brain Research Bulletin. 68: 54-8. PMID 16325004 DOI: 10.1016/j.brainresbull.2005.08.025  0.96
2005 Winkler C, Kirik D, Björklund A. Cell transplantation in Parkinson's disease: how can we make it work? Trends in Neurosciences. 28: 86-92. PMID 15667931 DOI: 10.1016/j.tins.2004.12.006  0.96
2005 Carlsson T, Winkler C, Burger C, Muzyczka N, Mandel RJ, Cenci A, Björklund A, Kirik D. Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors. Brain : a Journal of Neurology. 128: 559-69. PMID 15659429 DOI: 10.1093/brain/awh374  0.96
2004 Georgievska B, Carlsson T, Lacar B, Winkler C, Kirik D. Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor. The European Journal of Neuroscience. 20: 3121-30. PMID 15579166 DOI: 10.1111/j.1460-9568.2004.03770.x  0.96
2004 Grothe C, Timmer M, Scholz T, Winkler C, Nikkhah G, Claus P, Itoh N, Arenas E. Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons. Neurobiology of Disease. 17: 163-70. PMID 15474354 DOI: 10.1016/j.nbd.2004.07.007  0.96
2004 Timmer M, Müller-Ostermeyer F, Kloth V, Winkler C, Grothe C, Nikkhah G. Enhanced survival, reinnervation, and functional recovery of intrastriatal dopamine grafts co-transplanted with Schwann cells overexpressing high molecular weight FGF-2 isoforms. Experimental Neurology. 187: 118-36. PMID 15081594 DOI: 10.1016/j.expneurol.2004.01.013  0.96
2003 Winkler C, Bentlage C, Cenci MA, Nikkhah G, Björklund A. Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model. Neuroscience. 118: 1063-77. PMID 12732251 DOI: 10.1016/S0306-4522(03)00007-1  0.96
2002 Winkler C, Kirik D, Björklund A, Cenci MA. L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiology of Disease. 10: 165-86. PMID 12127155 DOI: 10.1006/nbdi.2002.0499  0.96
2002 Kirik D, Georgievska B, Burger C, Winkler C, Muzyczka N, Mandel RJ, Bjorklund A. Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 99: 4708-13. PMID 11917105 DOI: 10.1073/pnas.062047599  0.96
2002 Lundblad M, Andersson M, Winkler C, Kirik D, Wierup N, Cenci MA. Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. The European Journal of Neuroscience. 15: 120-32. PMID 11860512 DOI: 10.1046/j.0953-816x.2001.01843.x  0.96
2001 Kirik D, Winkler C, Björklund A. Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2889-96. PMID 11306640  0.96
2001 Roedter A, Winkler C, Samii M, Walter GF, Brandis A, Nikkhah G. Comparison of unilateral and bilateral intrastriatal 6-hydroxydopamine-induced axon terminal lesions: evidence for interhemispheric functional coupling of the two nigrostriatal pathways. The Journal of Comparative Neurology. 432: 217-29. PMID 11241387 DOI: 10.1002/cne.1098  0.96
2000 Winkler C, Kirik D, Björklund A, Dunnett SB. Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement. Progress in Brain Research. 127: 233-65. PMID 11142030 DOI: 10.1016/S0079-6123(00)27012-X  0.96
2000 Fricker-Gates RA, Winkler C, Kirik D, Rosenblad C, Carpenter MK, Björklund A. EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum. Experimental Neurology. 165: 237-47. PMID 10993684 DOI: 10.1006/exnr.2000.7482  0.96
2000 Rödter A, Winkler C, Samii M, Nikkhah G. Complex sensorimotor behavioral changes after terminal striatal 6-OHDA lesion and transplantation of dopaminergic embryonic micrografts. Cell Transplantation. 9: 197-214. PMID 10811393  0.96
1999 Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Björklund A. Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5990-6005. PMID 10407037  0.96
1999 Winkler C, Bentlage C, Nikkhah G, Samii M, Björklund A. Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants. Experimental Neurology. 155: 165-86. PMID 10072293 DOI: 10.1006/exnr.1998.6916  0.96
1998 Olsson M, Bjerregaard K, Winkler C, Gates M, Björklund A, Campbell K. Incorporation of mouse neural progenitors transplanted into the rat embryonic forebrain is developmentally regulated and dependent on regional and adhesive properties. The European Journal of Neuroscience. 10: 71-85. PMID 9753115  0.44
1998 Winkler C, Fricker RA, Gates MA, Olsson M, Hammang JP, Carpenter MK, Björklund A. Incorporation and glial differentiation of mouse EGF-responsive neural progenitor cells after transplantation into the embryonic rat brain. Molecular and Cellular Neurosciences. 11: 99-116. PMID 9647689 DOI: 10.1006/mcne.1998.0674  0.96
1997 Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP. Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice. Experimental Neurology. 148: 187-204. PMID 9398461 DOI: 10.1006/exnr.1997.6657  0.96
1997 Björklund A, Rosenblad C, Winkler C, Kirik D. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiology of Disease. 4: 186-200. PMID 9361295 DOI: 10.1006/nbdi.1997.0151  0.96
1997 Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK. Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease. The Journal of Comparative Neurology. 387: 96-113. PMID 9331174 DOI: 10.1002/(SICI)1096-9861(19971013)387:1<96::AID-CNE8>3.0.CO;2-I  0.96
1996 Lundberg C, Winkler C, Whittemore SR, Björklund A. Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globus pallidus. Neurobiology of Disease. 3: 33-50. PMID 9173911 DOI: 10.1006/nbdi.1996.0004  0.96
1996 Winkler C, Sauer H, Lee CS, Björklund A. Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7206-15. PMID 8929429  0.96
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