Year |
Citation |
Score |
2022 |
Quintino L, de Almeida LP, Lundberg C. Editorial: Gene therapy 2.0: Biotechnology for circuit engineering and complex therapeutic approaches. Frontiers in Bioengineering and Biotechnology. 10: 1082883. PMID 36483777 DOI: 10.3389/fbioe.2022.1082883 |
0.566 |
|
2022 |
Martinsson I, Quintino L, Garcia MG, Konings SC, Torres-Garcia L, Svanbergsson A, Stange O, England R, Deierborg T, Li JY, Lundberg C, Gouras GK. Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer's Disease. Frontiers in Aging Neuroscience. 14: 946297. PMID 35928998 DOI: 10.3389/fnagi.2022.946297 |
0.565 |
|
2022 |
Quintino L, Gubinelli F, Sarauskyte L, Arvidsson E, Davidsson M, Lundberg C, Heuer A. Automated quantification of neuronal swellings in a preclinical rodent model of Parkinson's disease detects region-specific changes in pathology. Journal of Neuroscience Methods. 109640. PMID 35690332 DOI: 10.1016/j.jneumeth.2022.109640 |
0.565 |
|
2020 |
Lockowandt M, Günther DM, Quintino L, Breger LS, Isaksson C, Lundberg C. Optimization of production and transgene expression of a retrogradely transported pseudotyped lentiviral vector. Journal of Neuroscience Methods. 108542. PMID 32017975 DOI: 10.1016/J.Jneumeth.2019.108542 |
0.792 |
|
2018 |
Quintino L, Avallone M, Brännstrom E, Kavanagh P, Lockowandt M, Garcia Jareño P, Breger LS, Lundberg C. GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration. Gene Therapy. PMID 30531868 DOI: 10.1038/S41434-018-0049-0 |
0.789 |
|
2018 |
Quintino L, Namislo A, Davidsson M, Breger LS, Kavanagh P, Avallone M, Elgstrand-Wettergren E, Isaksson C, Lundberg C. Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain. Molecular Therapy. Methods & Clinical Development. 11: 29-39. PMID 30324128 DOI: 10.1016/J.Omtm.2018.08.008 |
0.814 |
|
2018 |
Davidsson M, Díaz-Fernández P, Torroba M, Schwich OD, Aldrin-Kirk P, Quintino L, Heuer A, Wang G, Lundberg C, Bjorklund T. Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing. Rna (New York, N.Y.). PMID 29386333 DOI: 10.1261/Rna.063925.117 |
0.615 |
|
2016 |
Chtarto A, Humbert-Claude M, Bockstael O, Das AT, Boutry S, Breger LS, Klaver B, Melas C, Barroso-Chinea P, Gonzalez-Hernandez T, Muller RN, DeWitte O, Levivier M, Lundberg C, Berkhout B, et al. A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses. Molecular Therapy. Methods & Clinical Development. 5: 16027. PMID 27069954 DOI: 10.1038/mtm.2016.27 |
0.798 |
|
2016 |
Breger L, Wettergren EE, Quintino L, Lundberg C. Regulated Gene Therapy. Methods in Molecular Biology (Clifton, N.J.). 1382: 57-66. PMID 26611578 DOI: 10.1007/978-1-4939-3271-9_4 |
0.798 |
|
2015 |
Humbert-Claude M, Chtarto A, Bockstael O, Breger L, Das A, De Witte O, Berkhout B, Lundberg C, Levivier M, Tenenbaum L. Toward the Pharmacological Control of Gene Transfer-Mediated Intracerebral Neurotrophic Factor Administration Journal of Neurological Surgery Part a: Central European Neurosurgery. 76. DOI: 10.1055/s-0035-1564510 |
0.784 |
|
2015 |
Davidsson M, Aldrin-Kirk P, Díaz-Fernández P, Quintino L, Lundberg C, Björklund T. 345. A Novel Toolbox for RNA-Editing Based on Massively Parallel Screening Using Barcoded Viral Vectors Molecular Therapy. 23: S137-S138. DOI: 10.1016/S1525-0016(16)33954-5 |
0.55 |
|
2014 |
Wettergren EE, Quintino L, Lundberg C. Gene therapy using synthetic microRNA directed against GAD67 has beneficial effect on motor behaviour in 6-OHDA lesioned rats Journal of Gene Therapy Aspects. 1: 1. DOI: 10.7243/2057-164X-1-1 |
0.789 |
|
2014 |
Wettergren EE, Quintino L, Manfré G, Lundberg C. Gene therapy for Parkinson’s disease Neuromethods. 82: 181-191. DOI: 10.1007/978-1-62703-610-8_10 |
0.788 |
|
2013 |
Quintino L, Manfré G, Wettergren EE, Namislo A, Isaksson C, Lundberg C. Functional neuroprotection and efficient regulation of GDNF using destabilizing domains in a rodent model of Parkinson's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2169-80. PMID 23881415 DOI: 10.1038/Mt.2013.169 |
0.829 |
|
2013 |
Quintino L, Baudet A, Larsson J, Lundberg C. FACS binding assay for analysing GDNF interactions. Journal of Neuroscience Methods. 218: 25-8. PMID 23669067 DOI: 10.1016/j.jneumeth.2013.04.006 |
0.545 |
|
2013 |
Ã…kerblom M, Sachdeva R, Quintino L, Wettergren EE, Chapman KZ, Manfre G, Lindvall O, Lundberg C, Jakobsson J. Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9. Nature Communications. 4: 1770. PMID 23612311 DOI: 10.1038/Ncomms2801 |
0.81 |
|
2012 |
Lindgren N, Francardo V, Quintino L, Lundberg C, Cenci MA. A model of GDNF gene therapy in mice with 6-Hydroxydopamine lesions: time course of Neurorestorative effects and ERK1/2 activation. Journal of Parkinson's Disease. 2: 333-48. PMID 23938263 DOI: 10.3233/Jpd-012146 |
0.641 |
|
2012 |
Wettergren EE, Gussing F, Quintino L, Lundberg C. Novel disease-specific promoters for use in gene therapy for Parkinson's disease. Neuroscience Letters. 530: 29-34. PMID 23063686 DOI: 10.1016/J.Neulet.2012.09.059 |
0.797 |
|
2012 |
Tai K, Quintino L, Isaksson C, Gussing F, Lundberg C. Destabilizing domains mediate reversible transgene expression in the brain. Plos One. 7: e46269. PMID 23029456 DOI: 10.1371/Journal.Pone.0046269 |
0.821 |
|
2011 |
Horvath L, van Marion I, Taï K, Nielsen TT, Lundberg C. Knockdown of GAD67 protein levels normalizes neuronal activity in a rat model of Parkinson's disease. The Journal of Gene Medicine. 13: 188-97. PMID 21449035 DOI: 10.1002/Jgm.1555 |
0.62 |
|
2011 |
Tønnesen J, Parish CL, Sørensen AT, Andersson A, Lundberg C, Deisseroth K, Arenas E, Lindvall O, Kokaia M. Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. Plos One. 6: e17560. PMID 21394212 DOI: 10.1371/Journal.Pone.0017560 |
0.529 |
|
2011 |
Sørensen AT, Rogelius N, Lundberg C, Kokaia M. Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons. Experimental Neurology. 229: 274-81. PMID 21324317 DOI: 10.1016/J.Expneurol.2011.02.008 |
0.81 |
|
2010 |
Iwamoto M, Björklund T, Lundberg C, Kirik D, Wandless TJ. A general chemical method to regulate protein stability in the mammalian central nervous system. Chemistry & Biology. 17: 981-8. PMID 20851347 DOI: 10.1016/J.Chembiol.2010.07.009 |
0.522 |
|
2009 |
Staflin K, Zuchner T, Honeth G, Darabi A, Lundberg C. Identification of proteins involved in neural progenitor cell targeting of gliomas. Bmc Cancer. 9: 206. PMID 19558675 DOI: 10.1186/1471-2407-9-206 |
0.762 |
|
2009 |
Nielsen TT, Marion Iv, Hasholt L, Lundberg C. Neuron-specific RNA interference using lentiviral vectors. The Journal of Gene Medicine. 11: 559-69. PMID 19434604 DOI: 10.1002/jgm.1333 |
0.801 |
|
2009 |
Deierborg T, Staflin K, Pesic J, Roybon L, Brundin P, Lundberg C. Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries. Experimental Neurology. 219: 363-7. PMID 19427853 DOI: 10.1016/J.Expneurol.2009.05.002 |
0.804 |
|
2009 |
Gussing F, van Marion I, Ralets I, Lundberg C. Selective protein expression within the CNS using hybrid lentivirus. Methods in Molecular Biology (Clifton, N.J.). 515: 215-26. PMID 19378131 DOI: 10.1007/978-1-59745-559-6_14 |
0.794 |
|
2009 |
Nielsen TT, Jakobsson J, Rosenqvist N, Lundberg C. Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants. Bmc Biotechnology. 9: 13. PMID 19239708 DOI: 10.1186/1472-6750-9-13 |
0.803 |
|
2008 |
Lundberg C, Björklund T, Carlsson T, Jakobsson J, Hantraye P, Déglon N, Kirik D. Applications of lentiviral vectors for biology and gene therapy of neurological disorders. Current Gene Therapy. 8: 461-73. PMID 19075629 DOI: 10.2174/156652308786847996 |
0.825 |
|
2008 |
Rogelius N, Hebsgaard JB, Lundberg C, Parmar M. Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2. Molecular and Cellular Neurosciences. 38: 453-9. PMID 18524626 DOI: 10.1016/J.Mcn.2008.04.008 |
0.796 |
|
2007 |
Staflin K, Lindvall M, Zuchner T, Lundberg C. Instructive cross-talk between neural progenitor cells and gliomas. Journal of Neuroscience Research. 85: 2147-59. PMID 17526014 DOI: 10.1002/Jnr.21344 |
0.74 |
|
2006 |
Rogelius N, Jensen JB, Lundberg C, Parmar M. Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum. Experimental Neurology. 201: 388-98. PMID 16806175 DOI: 10.1016/J.Expneurol.2006.04.022 |
0.823 |
|
2006 |
Jakobsson J, Rosenqvist N, MÃ¥rild K, V Agoston D, Lundberg C. Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors. Journal of Neuroscience Research. 84: 58-67. PMID 16683227 DOI: 10.1002/Jnr.20872 |
0.828 |
|
2006 |
Jakobsson J, Nielsen TT, Staflin K, Georgievska B, Lundberg C. Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors. Gene Therapy. 13: 966-73. PMID 16511527 DOI: 10.1038/Sj.Gt.3302701 |
0.834 |
|
2006 |
Jakobsson J, Lundberg C. Lentiviral vectors for use in the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 484-93. PMID 16403676 DOI: 10.1016/J.Ymthe.2005.11.012 |
0.741 |
|
2005 |
Ericson C, Georgievska B, Lundberg C. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. The European Journal of Neuroscience. 22: 2755-64. PMID 16324109 DOI: 10.1111/j.1460-9568.2005.04503.x |
0.666 |
|
2005 |
Rosenqvist N, Jakobsson J, Lundberg C. Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. Cell Transplantation. 14: 129-38. PMID 15881422 DOI: 10.3727/000000005783983188 |
0.821 |
|
2005 |
Rogelius N, Ericson C, Lundberg C. In vivo labeling of neuroblasts in the subventricular zone of rats. Journal of Neuroscience Methods. 142: 285-93. PMID 15698668 DOI: 10.1016/J.Jneumeth.2004.09.008 |
0.801 |
|
2004 |
Georgievska B, Jakobsson J, Persson E, Ericson C, Kirik D, Lundberg C. Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector. Human Gene Therapy. 15: 934-44. PMID 15585109 DOI: 10.1089/Hum.2004.15.934 |
0.819 |
|
2004 |
Jakobsson J, Rosenqvist N, Thompson L, Barraud P, Lundberg C. Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator. Experimental Cell Research. 298: 611-23. PMID 15265707 DOI: 10.1016/J.Yexcr.2004.04.037 |
0.827 |
|
2004 |
Jakobsson J, Georgievska B, Ericson C, Lundberg C. Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector. The European Journal of Neuroscience. 19: 761-5. PMID 14984426 DOI: 10.1111/J.0953-816X.2003.03147.X |
0.823 |
|
2004 |
Wojciechowski AB, Englund U, Lundberg C, Warfvinge K. Survival and long distance migration of brain-derived precursor cells transplanted to adult rat retina. Stem Cells (Dayton, Ohio). 22: 27-38. PMID 14688389 DOI: 10.1634/stemcells.22-1-27 |
0.344 |
|
2003 |
Arvidsson A, Kirik D, Lundberg C, Mandel RJ, Andsberg G, Kokaia Z, Lindvall O. Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats. Neurobiology of Disease. 14: 542-56. PMID 14678770 DOI: 10.1016/J.Nbd.2003.08.002 |
0.668 |
|
2003 |
Jakobsson J, Ericson C, Rosenqvist N, Lundberg C. Lentiviral vectors. International Review of Neurobiology. 55: 111-22. PMID 12968533 DOI: 10.1016/S0074-7742(03)01004-3 |
0.788 |
|
2003 |
Jakobsson J, Ericson C, Jansson M, Björk E, Lundberg C. Targeted transgene expression in rat brain using lentiviral vectors. Journal of Neuroscience Research. 73: 876-85. PMID 12949915 DOI: 10.1002/Jnr.10719 |
0.832 |
|
2002 |
Falk A, Holmström N, Carlén M, Cassidy R, Lundberg C, Frisén J. Gene delivery to adult neural stem cells. Experimental Cell Research. 279: 34-9. PMID 12213211 DOI: 10.1006/Excr.2002.5569 |
0.376 |
|
2002 |
Lotharius J, Barg S, Wiekop P, Lundberg C, Raymon HK, Brundin P. Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. The Journal of Biological Chemistry. 277: 38884-94. PMID 12145295 DOI: 10.1074/jbc.M205518200 |
0.447 |
|
2002 |
Wojciechowski AB, Englund U, Lundberg C, Wictorin K, Warfvinge K. Subretinal transplantation of brain-derived precursor cells to young RCS rats promotes photoreceptor cell survival. Experimental Eye Research. 75: 23-37. PMID 12123634 DOI: 10.1006/Exer.2001.1172 |
0.678 |
|
2002 |
Rosenqvist N, HÃ¥rd Af Segerstad C, Samuelsson C, Johansen J, Lundberg C. Activation of silenced transgene expression in neural precursor cell lines by inhibitors of histone deacetylation. The Journal of Gene Medicine. 4: 248-57. PMID 12112642 DOI: 10.1002/Jgm.268 |
0.825 |
|
2002 |
Lundberg C, Englund U, Trono D, Björklund A, Wictorin K. Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain. Experimental Neurology. 175: 370-87. PMID 12061867 DOI: 10.1006/Exnr.2002.7888 |
0.773 |
|
2002 |
Georgievska B, Kirik D, Rosenblad C, Lundberg C, Björklund A. Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. Neuroreport. 13: 75-82. PMID 11924898 DOI: 10.1097/00001756-200201210-00019 |
0.594 |
|
2002 |
Kirik D, Rosenblad C, Burger C, Lundberg C, Johansen TE, Muzyczka N, Mandel RJ, Björklund A. Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2780-91. PMID 11923443 DOI: 10.1523/Jneurosci.22-07-02780.2002 |
0.57 |
|
2002 |
Wojciechowski AB, Englund U, Lundberg C, Warfvinge K. Long-term survival and glial differentiation of the brain-derived precursor cell line RN33B after subretinal transplantation to adult normal rats. Stem Cells (Dayton, Ohio). 20: 163-73. PMID 11897873 DOI: 10.1634/stemcells.20-2-163 |
0.324 |
|
2002 |
Ericson C, Wictorin K, Lundberg C. Ex vivo and in vitro studies of transgene expression in rat astrocytes transduced with lentiviral vectors. Experimental Neurology. 173: 22-30. PMID 11771936 DOI: 10.1006/Exnr.2001.7829 |
0.809 |
|
2002 |
Englund U, Fricker-Gates RA, Lundberg C, Björklund A, Wictorin K. Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with long-distance axonal projections. Experimental Neurology. 173: 1-21. PMID 11771935 DOI: 10.1006/Exnr.2001.7750 |
0.725 |
|
2000 |
Englund U, Ericson C, Rosenblad C, Mandel RJ, Trono D, Wictorin K, Lundberg C. The use of a recombinant lentiviral vector for ex vivo gene transfer into the rat CNS. Neuroreport. 11: 3973-7. PMID 11192612 DOI: 10.1097/00001756-200012180-00014 |
0.837 |
|
2000 |
Björklund A, Kirik D, Rosenblad C, Georgievska B, Lundberg C, Mandel RJ. Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model. Brain Research. 886: 82-98. PMID 11119690 DOI: 10.1016/S0006-8993(00)02915-2 |
0.631 |
|
2000 |
Rosenblad C, Grønborg M, Hansen C, Blom N, Meyer M, Johansen J, Dagø L, Kirik D, Patel UA, Lundberg C, Trono D, Björklund A, Johansen TE. In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin. Molecular and Cellular Neurosciences. 15: 199-214. PMID 10673327 DOI: 10.1006/Mcne.1999.0817 |
0.668 |
|
1997 |
Lundberg C, Martínez-Serrano A, Cattaneo E, McKay RD, Björklund A. Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum. Experimental Neurology. 145: 342-60. PMID 9217071 DOI: 10.1006/Exnr.1997.6503 |
0.324 |
|
1996 |
Lundberg C, Winkler C, Whittemore SR, Björklund A. Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globus pallidus. Neurobiology of Disease. 3: 33-50. PMID 9173911 DOI: 10.1006/Nbdi.1996.0004 |
0.542 |
|
1996 |
Lundberg C, Field PM, Ajayi YO, Raisman G, Björklund A. Conditionally immortalized neural progenitor cell lines integrate and differentiate after grafting to the adult rat striatum. A combined autoradiographic and electron microscopic study. Brain Research. 737: 295-300. PMID 8930379 DOI: 10.1016/0006-8993(96)00923-7 |
0.308 |
|
1996 |
Lundberg C, Björklund A. Host regulation of glial markers in intrastriatal grafts of conditionally immortalized neural stem cell lines. Neuroreport. 7: 847-52. PMID 8724658 |
0.305 |
|
1996 |
Lundberg C, Horellou P, Mallet J, Björklund A. Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: in vitro characterization and in vivo effects in the rat Parkinson model. Experimental Neurology. 139: 39-53. PMID 8635567 DOI: 10.1006/exnr.1996.0079 |
0.403 |
|
1995 |
Martínez-Serrano A, Lundberg C, Horellou P, Fischer W, Bentlage C, Campbell K, McKay RD, Mallet J, Björklund A. CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5668-80. PMID 7643209 DOI: 10.1523/Jneurosci.15-08-05668.1995 |
0.704 |
|
1994 |
Lundberg C, Wictorin K, Björklund A. Retrograde degenerative changes in the substantia nigra pars compacta following an excitotoxic lesion of the striatum. Brain Research. 644: 205-12. PMID 7914147 DOI: 10.1016/0006-8993(94)91681-0 |
0.666 |
|
1993 |
Campbell K, Kalén P, Lundberg C, Wictorin K, Rosengren E, Björklund A. Extracellular gamma-aminobutyric acid levels in the rat caudate-putamen: monitoring the neuronal and glial contribution by intracerebral microdialysis. Brain Research. 614: 241-50. PMID 8348317 DOI: 10.1016/0006-8993(93)91041-P |
0.68 |
|
1993 |
Campbell K, Kalén P, Wictorin K, Lundberg C, Mandel RJ, Björklund A. Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents. Neuroscience. 53: 403-15. PMID 8098510 DOI: 10.1016/0306-4522(93)90204-S |
0.695 |
|
1991 |
Horellou P, Lundberg C, Le Bourdellès B, Wictorin K, Brundin P, Kalén P, Björklund A, Mallet J. Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease. Journal De Physiologie. 85: 158-70. PMID 1687823 |
0.712 |
|
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