Kari A. Shirey, Ph.D. - Publications

Affiliations: 
2006 Miami University (Ohio), Oxford, OH 
Area:
Microbiology Biology, Immunology, Biochemistry

19/49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shirey KA, Lai W, Sunday ME, Cuttitta F, Blanco JCG, Vogel SN. Novel neuroendocrine role of γ-aminobutyric acid and gastrin-releasing peptide in the host response to influenza infection. Mucosal Immunology. PMID 36965691 DOI: 10.1016/j.mucimm.2023.03.004  0.324
2022 Gopalakrishnan A, Joseph J, Shirey KA, Keegan AD, Boukhvalova MS, Vogel SN, Blanco JCG. Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation. Frontiers in Immunology. 13: 968336. PMID 36052067 DOI: 10.3389/fimmu.2022.968336  0.432
2020 Richard K, Perkins DJ, Harberts EM, Song Y, Gopalakrishnan A, Shirey KA, Lai W, Vlk A, Mahurkar A, Nallar S, Hawkins LD, Ernst RK, Vogel SN. Dissociation of TRIF bias and adjuvanticity. Vaccine. PMID 32389496 DOI: 10.1016/J.Vaccine.2020.04.042  0.311
2017 Perrin-Cocon L, Aublin-Gex A, Sestito SE, Shirey KA, Patel MC, André P, Blanco JC, Vogel SN, Peri F, Lotteau V. TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection. Scientific Reports. 7: 40791. PMID 28106157 DOI: 10.1038/Srep40791  0.339
2016 Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, et al. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. Plos Pathogens. 12: e1005803. PMID 27482714 DOI: 10.1371/Journal.Ppat.1005803  0.369
2016 Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, et al. Novel strategies for targeting innate immune responses to influenza. Mucosal Immunology. PMID 26813341 DOI: 10.1038/Mi.2015.141  0.301
2014 Shirey KA, Lai W, Pletneva LM, Finkelman FD, Feola DJ, Blanco JC, Vogel SN. Agents that increase AAM differentiation blunt RSV-mediated lung pathology. Journal of Leukocyte Biology. 96: 951-5. PMID 25009233 DOI: 10.1189/Jlb.4Hi0414-226R  0.346
2013 Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, Gargan S, Quinn SR, Caamaño JH, Moynagh P, Vogel SN, O'Neill LA. Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15. The Journal of Biological Chemistry. 288: 25066-75. PMID 23873932 DOI: 10.1074/Jbc.M113.469122  0.307
2012 Polumuri SK, Jayakar GG, Shirey KA, Roberts ZJ, Perkins DJ, Pitha PM, Vogel SN. Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists. Journal of Immunology (Baltimore, Md. : 1950). 189: 50-60. PMID 22634618 DOI: 10.4049/Jimmunol.1003554  0.406
2012 Nhu QM, Shirey KA, Pennini ME, Stiltz J, Vogel SN. Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages. Innate Immunity. 18: 193-203. PMID 21239455 DOI: 10.1177/1753425910395044  0.448
2010 Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, Vogel SN. Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent. Mucosal Immunology. 3: 291-300. PMID 20404812 DOI: 10.1038/Mi.2010.6  0.481
2010 Cole LE, Laird MH, Seekatz A, Santiago A, Jiang Z, Barry E, Shirey KA, Fitzgerald KA, Vogel SN. Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling. Journal of Leukocyte Biology. 87: 275-81. PMID 19889726 DOI: 10.1189/Jlb.0909619  0.362
2008 Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD. Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. Science Signaling. 1: ra17. PMID 19109239 DOI: 10.1126/Scisignal.1164795  0.387
2008 Shirey KA, Cole LE, Keegan AD, Vogel SN. Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. Journal of Immunology (Baltimore, Md. : 1950). 181: 4159-67. PMID 18768873 DOI: 10.4049/Jimmunol.181.6.4159  0.398
2008 Cole LE, Santiago A, Barry E, Kang TJ, Shirey KA, Roberts ZJ, Elkins KL, Cross AS, Vogel SN. Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 180: 6885-91. PMID 18453609 DOI: 10.4049/Jimmunol.180.10.6885  0.439
2006 Shirey KA, Jung JY, Carlin JM. Up-regulation of gamma interferon receptor expression due to Chlamydia-toll-like receptor interaction does not enhance signal transducer and activator of transcription 1 signaling. Infection and Immunity. 74: 6877-84. PMID 17030574 DOI: 10.1128/Iai.00505-06  0.724
2006 Shirey KA, Carlin JM. Chlamydiae modulate gamma interferon, interleukin-1 beta, and tumor necrosis factor alpha receptor expression in HeLa cells. Infection and Immunity. 74: 2482-6. PMID 16552084 DOI: 10.1128/Iai.74.4.2482-2486.2006  0.662
2006 Shirey KA, Jung JY, Maeder GS, Carlin JM. Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 53-62. PMID 16426148 DOI: 10.1089/Jir.2006.26.53  0.714
2003 Robinson CM, Shirey KA, Carlin JM. Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 413-21. PMID 13678429 DOI: 10.1089/107999003322277829  0.55
Low-probability matches (unlikely to be authored by this person)
2017 Prantner D, Shirey KA, Lai W, Lu W, Cole AM, Vogel SN, Garzino-Demo A. The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection. Journal of Leukocyte Biology. PMID 28729359 DOI: 10.1189/Jlb.2A1215-567Rr  0.293
2007 Cole LE, Shirey KA, Barry E, Santiago A, Rallabhandi P, Elkins KL, Puche AC, Michalek SM, Vogel SN. Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages. Infection and Immunity. 75: 4127-37. PMID 17517865 DOI: 10.1128/Iai.01868-06  0.293
2011 Shirey KA, Nhu QM, Yim KC, Roberts ZJ, Teijaro JR, Farber DL, Blanco JC, Vogel SN. The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo. Journal of Leukocyte Biology. 89: 351-7. PMID 21084628 DOI: 10.1189/Jlb.0410216  0.288
2015 Piao W, Shirey KA, Ru LW, Lai W, Szmacinski H, Snyder GA, Sundberg EJ, Lakowicz JR, Vogel SN, Toshchakov VY. A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza. Cell Reports. 11: 1941-1952. PMID 26095366 DOI: 10.1016/J.Celrep.2015.05.035  0.287
2012 Rallabhandi P, Phillips RL, Boukhvalova MS, Pletneva LM, Shirey KA, Gioannini TL, Weiss JP, Chow JC, Hawkins LD, Vogel SN, Blanco JC. Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2. Mbio. 3. PMID 22872782 DOI: 10.1128/Mbio.00218-12  0.286
2023 Vlk AM, Prantner D, Shirey KA, Perkins DJ, Buzza MS, Thumbigere-Math V, Keegan AD, Vogel SN. M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice. Mbio. e0120823. PMID 37768050 DOI: 10.1128/mbio.01208-23  0.274
2014 Shirey KA, Lai W, Pletneva LM, Karp CL, Divanovic S, Blanco JC, Vogel SN. Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology. Mucosal Immunology. 7: 549-57. PMID 24064666 DOI: 10.1038/Mi.2013.71  0.273
2014 Patel MC, Shirey KA, Pletneva LM, Boukhvalova MS, Garzino-Demo A, Vogel SN, Blanco JC. Novel drugs targeting Toll-like receptors for antiviral therapy. Future Virology. 9: 811-829. PMID 25620999 DOI: 10.2217/Fvl.14.70  0.265
2019 Shirey KA, Perkins DJ, Lai W, Zhang W, Fernando LR, Gusovsky F, Blanco JCG, Vogel SN. Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection. Mbio. 10. PMID 31064834 DOI: 10.1128/Mbio.00810-19  0.265
2018 Shirey KA, Sunday ME, Lai W, Patel MC, Blanco JCG, Cuttitta F, Vogel SN. Novel role of gastric releasing peptide-mediated signaling in the host response to influenza infection. Mucosal Immunology. PMID 30327535 DOI: 10.1038/S41385-018-0081-9  0.263
2008 Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, Mohapatra SK, Crasta OR, Vogel SN, Cross AS, Hassel BA. An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 20816-21. PMID 19075243 DOI: 10.1073/Pnas.0807265105  0.239
2011 Cole LE, Mann BJ, Shirey KA, Richard K, Yang Y, Gearhart PJ, Chesko KL, Viscardi RM, Vogel SN. Role of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge. Journal of Leukocyte Biology. 90: 787-97. PMID 21750122 DOI: 10.1189/Jlb.0111014  0.225
2020 Shirey KA, Lai W, Brown LJ, Blanco JCG, Beadenkopf R, Wang Y, Vogel SN, Snyder GA. Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease. Innate Immunity. 26: 26-34. PMID 31955622 DOI: 10.1177/1753425919846281  0.222
2013 Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature. 497: 498-502. PMID 23636320 DOI: 10.1038/Nature12118  0.219
2012 Qualls JE, Subramanian C, Rafi W, Smith AM, Balouzian L, DeFreitas AA, Shirey KA, Reutterer B, Kernbauer E, Stockinger S, Decker T, Miyairi I, Vogel SN, Salgame P, Rock CO, et al. Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1. Cell Host & Microbe. 12: 313-23. PMID 22980328 DOI: 10.1016/J.Chom.2012.07.012  0.213
2022 Fink MY, Qi X, Shirey KA, Fanaroff R, Chapoval S, Viscardi RM, Vogel SN, Keegan AD. Mice Expressing Cosegregating Single Nucleotide Polymorphisms (D298G and N397I) in TLR4 Have Enhanced Responses to House Dust Mite Allergen. Journal of Immunology (Baltimore, Md. : 1950). 208: 2085-2097. PMID 35396219 DOI: 10.4049/jimmunol.2100926  0.203
2016 Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, et al. The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation. Infection and Immunity. PMID 27045038 DOI: 10.1128/Iai.01526-15  0.197
2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, ... ... Shirey KA, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 41: 14-20. PMID 25035950 DOI: 10.1016/J.Immuni.2014.06.008  0.188
2016 Keegan AD, Shirey KA, Bagdure D, Blanco J, Viscardi RM, Vogel SN. Enhanced allergic responsiveness after early childhood infection with respiratory viruses: are long-lived alternatively-activated macrophages the missing link? Pathogens and Disease. PMID 27178560 DOI: 10.1093/Femspd/Ftw047  0.18
2022 Vogel SN, Richard K, Shirey KA, Sylla FYD, Boukhvalova MS, Blanco JCG. Evidence for Interplay Between the Renin-Angiotensin System and Toll-Like Receptor 4 Signaling Pathways in the Induction of Virus-Induced Acute Lung Injury. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 36206057 DOI: 10.1089/jir.2022.0081  0.163
2021 Richard K, Piepenbrink KH, Shirey KA, Gopalakrishnan A, Nallar S, Prantner DJ, Perkins DJ, Lai W, Vlk A, Toshchakov VY, Feng C, Fanaroff R, Medvedev AE, Blanco JCG, Vogel SN. A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses. The Journal of Experimental Medicine. 218. PMID 33216117 DOI: 10.1084/jem.20200675  0.16
2021 Shirey KA, Blanco JCG, Vogel SN. Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury. Frontiers in Immunology. 12: 705080. PMID 34282358 DOI: 10.3389/fimmu.2021.705080  0.155
2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, ... ... Shirey KA, et al. Correction tp Macrophage activation and polarization: Nomenclature and experimental guidelines [Immunity, 41, 2014 (14-20)] Immunity. 41: 339-340. DOI: 10.1016/J.Immuni.2014.07.009  0.15
2012 Chen WH, Toapanta FR, Shirey KA, Zhang L, Giannelou A, Page C, Frieman MB, Vogel SN, Cross AS. Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza. Immunology Letters. 141: 227-34. PMID 22037624 DOI: 10.1016/J.Imlet.2011.10.009  0.141
2014 Blanco JC, Boukhvalova MS, Pletneva LM, Shirey KA, Vogel SN. A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology. Vaccine. 32: 1495-500. PMID 24252693 DOI: 10.1016/J.Vaccine.2013.11.032  0.138
2017 Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK. Host-based lipid inflammation drives pathogenesis in Francisella infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109289 DOI: 10.1073/Pnas.1712887114  0.128
2018 Patel MC, Shirey KA, Boukhvalova MS, Vogel SN, Blanco JCG. Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections. Mbio. 9. PMID 29535197 DOI: 10.1128/Mbio.00246-18  0.109
2020 Doran SJ, Henry RJ, Shirey KA, Barrett JP, Ritzel RM, Lai W, Blanco JC, Faden AI, Vogel SN, Loane DJ. Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function. Critical Care Medicine. PMID 32149839 DOI: 10.1097/Ccm.0000000000004273  0.096
2012 Marohn ME, Santiago AE, Shirey KA, Lipsky M, Vogel SN, Barry EM. Members of the Francisella tularensis phagosomal transporter subfamily of major facilitator superfamily transporters are critical for pathogenesis. Infection and Immunity. 80: 2390-401. PMID 22508856 DOI: 10.1128/Iai.00144-12  0.089
2010 Blanco JC, Boukhvalova MS, Shirey KA, Prince GA, Vogel SN. New insights for development of a safe and protective RSV vaccine. Human Vaccines. 6: 482-92. PMID 20671419 DOI: 10.4161/Hv.6.6.11562  0.06
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