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Renato Xavier Santos - Publications

Affiliations: 
Center for Neuroscience and Cell Biology University of Coimbra, Coimbra, Coimbra, Portugal 
Website:
http://www.cnbc.pt/research/areaA3_2m.asp

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kondak C, Leith M, Baddeley TC, Santos RX, Harrington CR, Wischik CM, Riedel G, Klein J. Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice. International Journal of Molecular Sciences. 24. PMID 37445987 DOI: 10.3390/ijms241310810  0.397
2016 Candeias E, Duarte AI, Sebastião I, Fernandes MA, Plácido AI, Carvalho C, Correia S, Santos RX, Seiça R, Santos MS, Oliveira CR, Moreira PI. Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology. Molecular Neurobiology. PMID 27730513 DOI: 10.1007/S12035-016-0155-1  0.756
2014 Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Seiça R, Santos MS, Moreira PI. Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes. Molecular and Cellular Biochemistry. 394: 13-22. PMID 24833464 DOI: 10.1007/S11010-014-2076-5  0.791
2014 Plácido AI, Pereira CM, Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Oliveira CR, Moreira PI. The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease. Biochimica Et Biophysica Acta. 1842: 1444-53. PMID 24832819 DOI: 10.1016/J.Bbadis.2014.05.003  0.737
2014 Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Duarte AI, Santos MS, Moreira PI. Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats. Biochimica Et Biophysica Acta. 1842: 1154-66. PMID 24747740 DOI: 10.1016/J.Bbadis.2014.04.011  0.755
2014 Santos RX, Moreira PI. Mtor is a potential therapeutic target for alzheimer's disease Advances in Cognitive and Behavioral Sciences. 183-207.  0.536
2013 Correia SC, Carvalho C, Cardoso S, Santos RX, Plácido AI, Candeias E, Duarte AI, Moreira PI. Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question! Current Pharmaceutical Design. 19: 6809-22. PMID 23530518 DOI: 10.2174/1381612811319380013  0.754
2013 Carvalho C, Machado N, Mota PC, Correia SC, Cardoso S, Santos RX, Santos MS, Oliveira CR, Moreira PI. Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies. Journal of Alzheimer's Disease : Jad. 35: 623-35. PMID 23478310 DOI: 10.3233/Jad-130005  0.729
2013 Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido A, Santos MS, Oliveira CR, Moreira PI. Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochimica Et Biophysica Acta. 1832: 527-41. PMID 23314196 DOI: 10.1016/J.Bbadis.2013.01.008  0.766
2013 Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxidants & Redox Signaling. 18: 2444-57. PMID 23216311 DOI: 10.1089/Ars.2012.5039  0.82
2013 Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Current Alzheimer Research. 10: 406-19. PMID 23061885 DOI: 10.2174/1567205011310040006  0.809
2013 Cardoso S, Santos RX, Correia SC, Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance. Neurobiology of Disease. 49: 1-12. PMID 22940631 DOI: 10.1016/J.Nbd.2012.08.008  0.78
2013 Cardoso S, Correia SC, Santos RX, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins. Current Molecular Medicine. 13: 586-601. PMID 22934852 DOI: 10.2174/1566524011313040010  0.802
2013 Carvalho C, Santos RX, Cardoso S, Correia SC, Moreira PI. Chronic hypoxia, type 2 diabetes and Alzheimer's disease: A dangerous triad Hypoxia: Causes, Types and Management. 21-34.  0.708
2012 Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Plácido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. Iubmb Life. 64: 951-7. PMID 23129399 DOI: 10.1002/Iub.1098  0.773
2012 Correia SC, Santos RX, Cardoso S, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Alzheimer disease as a vascular disorder: where do mitochondria fit? Experimental Gerontology. 47: 878-86. PMID 22824543 DOI: 10.1016/J.Exger.2012.07.006  0.777
2012 Carvalho C, Cardoso S, Correia SC, Santos RX, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes. 61: 1234-42. PMID 22427376 DOI: 10.2337/Db11-1186  0.779
2012 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Advances in Experimental Medicine and Biology. 724: 205-21. PMID 22411245 DOI: 10.1007/978-1-4614-0653-2_16  0.834
2012 Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, Oliveira CR, Moreira PI. Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Research. 1441: 64-78. PMID 22290178 DOI: 10.1016/J.Brainres.2011.12.063  0.766
2012 Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radical Research. 46: 565-76. PMID 22149654 DOI: 10.3109/10715762.2011.648188  0.791
2012 Correia SC, Santos RX, Cardoso SM, Santos MS, Oliveira CR, Moreira PI. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α. Neurobiology of Disease. 45: 206-18. PMID 21854848 DOI: 10.1016/J.Nbd.2011.08.005  0.77
2011 Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Current Pharmaceutical Design. 17: 3381-9. PMID 21902670 DOI: 10.2174/138161211798072490  0.811
2011 Santos RX, Correia SC, Cardoso S, Carvalho C, Santos MS, Moreira PI. Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease. Journal of Neurochemistry. 117: 927-36. PMID 21447003 DOI: 10.1111/J.1471-4159.2011.07262.X  0.721
2011 Santos RX, Correia SC, Carvalho C, Cardoso S, Santos MS, Moreira PI. Mitophagy in neurodegeneration: an opportunity for therapy? Current Drug Targets. 12: 790-9. PMID 21269269 DOI: 10.2174/138945011795528813  0.798
2011 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Research Reviews. 10: 264-73. PMID 21262392 DOI: 10.1016/J.Arr.2011.01.001  0.801
2011 Cardoso S, Carvalho C, Santos R, Correia S, Santos MS, Seiça R, Oliveira CR, Moreira PI. Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters. Synapse (New York, N.Y.). 65: 457-66. PMID 20853444 DOI: 10.1002/Syn.20863  0.698
2011 Cardoso S, Santos RX, Carvalho C, Correia S, Santos MS, Moreira PI. Mitochondrial Uncoupling Proteins and Oxidative Stress: Implications for Diabetes and Neurodegeneration Free Radicals and Antioxidants. 1: 4-14. DOI: 10.5530/Ax.2011.2.3  0.795
2011 Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Zhu X, Smith MA, Perry G. Association of mitochondrial signaling in Alzheimer's disease and hypoxia Molecular Aspects of Neurodegeneration and Neuroprotection. 50-61. DOI: 10.2174/978160805092511101010050  0.811
2011 Cardoso S, Carvalho C, Correia S, Santos RX, Santos MS, Moreira PI. Mitochondrial uncoupling proteins - therapeutic targets in neurodegeneration? Neurodegeneration: Theory, Disorders and Treatments. 107-124.  0.738
2011 Carvalho C, Correia SC, Santos RX, Cardoso S, Santos MS, Moreira PI. Diabetes, mitochondria and brain endothelium dysfunction: A dangerous triad for neurodegeneration? Mitochondria: Structure, Functions and Dysfunctions. 553-577.  0.729
2010 Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Frontiers in Aging Neuroscience. 2. PMID 20838473 DOI: 10.3389/Fnagi.2010.00138  0.836
2010 Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. International Journal of Clinical and Experimental Pathology. 3: 570-81. PMID 20661404  0.829
2010 Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1209-18. PMID 20586699 DOI: 10.1586/Ern.10.84  0.808
2010 Santos RX, Cardoso S, Correia S, Carvalho C, Santos MS, Moreira PI. Targeting autophagy in the brain: a promising approach? Central Nervous System Agents in Medicinal Chemistry. 10: 158-68. PMID 20518730 DOI: 10.2174/187152410791196350  0.763
2010 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. Journal of Alzheimer's Disease : Jad. 20: S475-85. PMID 20463394 DOI: 10.3233/Jad-2010-100669  0.827
2010 Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 20: S401-12. PMID 20463393 DOI: 10.3233/Jad-2010-100666  0.835
2010 Correia SC, Santos RX, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI. Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease? Current Aging Science. 3: 113-26. PMID 20167003 DOI: 10.2174/1874609811003020113  0.765
2010 Correia SC, Santos RX, Santos MS, Moreira PI. Mitochondrial reactive oxygen species preconditioning protects brain cells against hyperglycemia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1901  0.76
2009 Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel, Switzerland). 2: 250-286. PMID 27713238 DOI: 10.3390/Ph2030250  0.804
2009 Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. Journal of Bioenergetics and Biomembranes. 41: 433-40. PMID 19830532 DOI: 10.1007/S10863-009-9247-1  0.84
2009 Carvalho C, Santos RX, Cardoso S, Correia S, Oliveira PJ, Santos MS, Moreira PI. Doxorubicin: the good, the bad and the ugly effect. Current Medicinal Chemistry. 16: 3267-85. PMID 19548866 DOI: 10.2174/092986709788803312  0.685
2009 Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. Journal of Alzheimer's Disease : Jad. 18: 483-507. PMID 19542630 DOI: 10.3233/Jad-2009-1155  0.792
2009 Santos RX, Cardoso S, Silva S, Correia S, Carvalho C, Crisóstomo J, Rodrigues L, Amaral C, Louro T, Matafome P, Santos MS, Proença T, Duarte AI, Seiça R, Moreira PI. Food deprivation promotes oxidative imbalance in rat brain. Journal of Food Science. 74: H8-H14. PMID 19200099 DOI: 10.1111/J.1750-3841.2008.00982.X  0.695
2008 Cardoso S, Santos RX, Carvalho C, Correia S, Pereira GC, Pereira SS, Oliveira PJ, Santos MS, Proença T, Moreira PI. Doxorubicin increases the susceptibility of brain mitochondria to Ca(2+)-induced permeability transition and oxidative damage. Free Radical Biology & Medicine. 45: 1395-402. PMID 18775776 DOI: 10.1016/J.Freeradbiomed.2008.08.008  0.762
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