Paul J. Harrison, MA, BM, BCh, DM (Oxon), FRCPsych - Publications

Affiliations: 
Psychiatry University of Oxford, Oxford, United Kingdom 

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Atkinson LZ, Colbourne L, Smith A, Harmer CH, Nobre AC, Rendell J, Jones H, Hinds C, Mould A, Tunbridge EM, Cipriani A, Geddes JR, Saunders KEA, Harrison PJ. The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study. Trials. 20: 120. PMID 30755265 DOI: 10.1186/s13063-019-3175-0  0.92
2018 Gordon-Smith K, Saunders K, Geddes JR, Harrison PJ, Hinds C, Craddock N, Jones I, Jones L. Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network. Journal of Affective Disorders. 246: 789-793. PMID 30623825 DOI: 10.1016/j.jad.2018.12.099  0.56
2018 Deakin IH, Godlewska BR, Walker MA, Huang GJ, Schwab MH, Nave KA, Law AJ, Harrison PJ. Altered hippocampal gene expression and structure in transgenic mice overexpressing neuregulin 1 (Nrg1) type I. Translational Psychiatry. 8: 229. PMID 30348978 DOI: 10.1038/s41398-018-0288-2  1
2018 Strawbridge RJ, Ward J, Lyall LM, Tunbridge EM, Cullen B, Graham N, Ferguson A, Johnston KJA, Lyall DM, Mackay D, Cavanagh J, Howard DM, Adams MJ, Deary I, Escott-Price V, ... ... Harrison PJ, et al. Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression. Translational Psychiatry. 8: 178. PMID 30181555 DOI: 10.1038/s41398-018-0236-1  0.92
2018 Ang G, McKillop LE, Purple R, Blanco-Duque C, Peirson SN, Foster RG, Harrison PJ, Sprengel R, Davies KE, Oliver PL, Bannerman DM, Vyazovskiy VV. Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders. Translational Psychiatry. 8: 154. PMID 30108203 DOI: 10.1038/s41398-018-0199-2  0.68
2018 Strawbridge RJ, Ward J, Cullen B, Tunbridge EM, Hartz S, Bierut L, Horton A, Bailey MES, Graham N, Ferguson A, Lyall DM, Mackay D, Pidgeon LM, Cavanagh J, Pell JP, ... ... Harrison PJ, et al. Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry. 8: 39. PMID 29391395 DOI: 10.1038/s41398-017-0079-1  0.92
2017 Harrison PJ, Geddes JR, Tunbridge EM. The Emerging Neurobiology of Bipolar Disorder. Trends in Neurosciences. PMID 29169634 DOI: 10.1016/j.tins.2017.10.006  0.92
2017 García-Bea A, Bermudez I, Harrison PJ, Lane TA. A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding. Journal of Psychopharmacology (Oxford, England). 269881117715597. PMID 28655286 DOI: 10.1177/0269881117715597  0.52
2017 Sanderson DJ, Lee A, Sprengel R, Seeburg PH, Harrison PJ, Bannerman DM. Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia. Scientific Reports. 7: 1765. PMID 28496171 DOI: 10.1038/s41598-017-01925-8  0.68
2017 Houghton KT, Forrest A, Awad A, Atkinson LZ, Stockton S, Harrison PJ, Geddes JR, Cipriani A. Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis. Bmj Open. 7: e013433. PMID 28348186 DOI: 10.1136/bmjopen-2016-013433  0.56
2017 Boerner T, Bygrave A, Chen J, Fernando A, Jackson S, Barkus C, Sprengel R, Seeburg PH, Harrison PJ, Gilmour G, Bannerman DM, Sanderson DJ. The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice. The European Journal of Neuroscience. PMID 28186680 DOI: 10.1111/ejn.13539  0.68
2016 Barkus C, Korn C, Stumpenhorst K, Laatikainen LM, Ballard D, Lee S, Sharp T, Harrison PJ, Bannerman DM, Weinberger DR, Chen J, Tunbridge EM. Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly-Specific, Novel Mouse Model of Altered COMT Activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27388330 DOI: 10.1038/npp.2016.119  0.92
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Harrison PJ, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/j.biopsych.2016.05.004  0.72
2016 Cipriani A, Saunders K, Attenburrow MJ, Stefaniak J, Panchal P, Stockton S, Lane TA, Tunbridge EM, Geddes JR, Harrison PJ. A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development. Molecular Psychiatry. PMID 27240535 DOI: 10.1038/mp.2016.86  0.92
2016 García-Bea A, Walker MA, Hyde TM, Kleinman JE, Harrison PJ, Lane TA. Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study. Schizophrenia Research. PMID 27130562 DOI: 10.1016/j.schres.2016.04.015  1
2016 Harrison PJ, Cipriani A, Harmer CJ, Nobre AC, Saunders K, Goodwin GM, Geddes JR. Innovative approaches to bipolar disorder and its treatment. Annals of the New York Academy of Sciences. 1366: 76-89. PMID 27111134 DOI: 10.1111/nyas.13048  1
2016 Harrison PJ, Cader MZ, Geddes JR. Reprogramming psychiatry: stem cells and bipolar disorder. Lancet (London, England). 387: 823-5. PMID 26972063 DOI: 10.1016/S0140-6736(16)00235-X  0.56
2016 Saunders KE, Cipriani A, Rendell J, Attenburrow MJ, Nelissen N, Bilderbeck AC, Vasudevan SR, Churchill G, Goodwin GM, Nobre AC, Harmer CJ, Harrison PJ, Geddes JR. Oxford Lithium Trial (OxLith) of the early affective, cognitive, neural and biochemical effects of lithium carbonate in bipolar disorder: study protocol for a randomised controlled trial. Trials. 17: 116. PMID 26936776 DOI: 10.1186/s13063-016-1230-7  1
2016 Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM. Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D-amino acid oxidase knockout (Dao(-/-) ) mice. The European Journal of Neuroscience. PMID 26833794 DOI: 10.1111/ejn.13192  0.92
2015 Geddes JR, Gardiner A, Rendell J, Voysey M, Tunbridge E, Hinds C, Yu LM, Hainsworth J, Attenburrow MJ, Simon J, Goodwin GM, Harrison PJ. Comparative evaluation of quetiapine plus lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in bipolar depression (CEQUEL): a 2 × 2 factorial randomised trial. The Lancet. Psychiatry. PMID 26687300 DOI: 10.1016/S2215-0366(15)00450-2  1
2015 Tunbridge EM, Dunn G, Murray RM, Evans N, Lister R, Stumpenhorst K, Harrison PJ, Morrison PD, Freeman D. Genetic moderation of the effects of cannabis: Catechol-O-methyltransferase (COMT) affects the impact of Δ9-tetrahydrocannabinol (THC) on working memory performance but not on the occurrence of psychotic experiences. Journal of Psychopharmacology (Oxford, England). PMID 26464454 DOI: 10.1177/0269881115609073  1
2015 Sheaves B, Porcheret K, Tsanas A, Espie CA, Foster RG, Freeman D, Harrison PJ, Wulff K, Goodwin GM. Insomnia, Nightmares, and Chronotype as Markers of Risk for Severe Mental Illness: Results from a Student Population. Sleep. PMID 26350467 DOI: 10.5665/sleep.5342  1
2015 Harrison PJ. Molecular neurobiological clues to the pathogenesis of bipolar disorder. Current Opinion in Neurobiology. 36: 1-6. PMID 26210959 DOI: 10.1016/j.conb.2015.07.002  1
2015 Freeman D, Sheaves B, Goodwin GM, Yu LM, Harrison PJ, Emsley R, Bostock S, Foster RG, Wadekar V, Hinds C, Espie CA. Effects of cognitive behavioural therapy for insomnia on the mental health of university students: study protocol for a randomized controlled trial. Trials. 16: 236. PMID 26016697 DOI: 10.1186/s13063-015-0756-4  1
2015 Pritchett D, Jagannath A, Brown LA, Tam SK, Hasan S, Gatti S, Harrison PJ, Bannerman DM, Foster RG, Peirson SN. Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light. Plos One. 10: e0125523. PMID 25950516 DOI: 10.1371/journal.pone.0125523  1
2015 Pritchett D, Hasan S, Tam SK, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Bannerman DM, Peirson SN. d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption. The European Journal of Neuroscience. 41: 1167-79. PMID 25816902 DOI: 10.1111/ejn.12880  1
2015 Cousijn H, Tunbridge EM, Rolinski M, Wallis G, Colclough GL, Woolrich MW, Nobre AC, Harrison PJ. Modulation of hippocampal theta and hippocampal-prefrontal cortex function by a schizophrenia risk gene. Human Brain Mapping. 36: 2387-95. PMID 25757652 DOI: 10.1002/hbm.22778  1
2015 Harrison PJ. GABA circuitry, cells and molecular regulation in schizophrenia: Life in the graveyard. Schizophrenia Research. PMID 25694185 DOI: 10.1016/j.schres.2015.02.003  1
2015 Harrison PJ. Recent genetic findings in schizophrenia and their therapeutic relevance. Journal of Psychopharmacology (Oxford, England). 29: 85-96. PMID 25315827 DOI: 10.1177/0269881114553647  1
2015 De Filippis B, Lyon L, Taylor A, Lane T, Burnet PW, Harrison PJ, Bannerman DM. The role of group II metabotropic glutamate receptors in cognition and anxiety: comparative studies in GRM2(-/-), GRM3(-/-) and GRM2/3(-/-) knockout mice. Neuropharmacology. 89: 19-32. PMID 25158312 DOI: 10.1016/j.neuropharm.2014.08.010  1
2015 Freeman D, Dunn G, Murray RM, Evans N, Lister R, Antley A, Slater M, Godlewska B, Cornish R, Williams J, Di Simplicio M, Igoumenou A, Brenneisen R, Tunbridge EM, Harrison PJ, et al. How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to paranoia. Schizophrenia Bulletin. 41: 391-9. PMID 25031222 DOI: 10.1093/schbul/sbu098  1
2015 Harrison PJ. The current and potential impact of genetics and genomics on neuropsychopharmacology. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 671-81. PMID 23528807 DOI: 10.1016/j.euroneuro.2013.02.005  1
2014 Barkus C, Sanderson DJ, Rawlins JN, Walton ME, Harrison PJ, Bannerman DM. What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit. Molecular Psychiatry. 19: 1060-70. PMID 25224260 DOI: 10.1038/mp.2014.91  1
2014 Cousijn H, Eissing M, Fernández G, Fisher SE, Franke B, Zwiers M, Harrison PJ, Arias-Vásquez A. No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure. Schizophrenia Research. 159: 329-32. PMID 25217366 DOI: 10.1016/j.schres.2014.08.007  1
2014 Tao R, Cousijn H, Jaffe AE, Burnet PW, Edwards F, Eastwood SL, Shin JH, Lane TA, Walker MA, Maher BJ, Weinberger DR, Harrison PJ, Hyde TM, Kleinman JE. Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706. Jama Psychiatry. 71: 1112-20. PMID 25162540 DOI: 10.1001/jamapsychiatry.2014.1079  1
2014 Schweimer JV, Coullon GS, Betts JF, Burnet PW, Engle SJ, Brandon NJ, Harrison PJ, Sharp T. Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo. The European Journal of Neuroscience. 40: 2999-3009. PMID 25040393 DOI: 10.1111/ejn.12667  1
2014 Cousijn H, Haegens S, Wallis G, Near J, Stokes MG, Harrison PJ, Nobre AC. Resting GABA and glutamate concentrations do not predict visual gamma frequency or amplitude. Proceedings of the National Academy of Sciences of the United States of America. 111: 9301-6. PMID 24927588 DOI: 10.1073/pnas.1321072111  1
2014 Betts JF, Schweimer JV, Burnham KE, Burnet PW, Sharp T, Harrison PJ. D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine. Frontiers in Synaptic Neuroscience. 6: 11. PMID 24822045 DOI: 10.3389/fnsyn.2014.00011  1
2014 Haegens S, Cousijn H, Wallis G, Harrison PJ, Nobre AC. Inter- and intra-individual variability in alpha peak frequency. Neuroimage. 92: 46-55. PMID 24508648 DOI: 10.1016/j.neuroimage.2014.01.049  1
2014 Carter CS, Bullmore ET, Harrison P. Is there a flame in the brain in psychosis? Biological Psychiatry. 75: 258-9. PMID 24439553 DOI: 10.1016/j.biopsych.2013.10.023  1
2014 Coutinho E, Harrison P, Vincent A. Do neuronal autoantibodies cause psychosis? A neuroimmunological perspective. Biological Psychiatry. 75: 269-75. PMID 24090795 DOI: 10.1016/j.biopsych.2013.07.040  1
2013 Lane TA, Boerner T, Bannerman DM, Kew JN, Tunbridge EM, Sharp T, Harrison PJ. Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice. Bmc Neuroscience. 14: 102. PMID 24053122 DOI: 10.1186/1471-2202-14-102  1
2013 Laatikainen LM, Sharp T, Harrison PJ, Tunbridge EM. Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. Plos One. 8: e61839. PMID 23613951 DOI: 10.1371/journal.pone.0061839  1
2013 Tunbridge EM, Farrell SM, Harrison PJ, Mackay CE. Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest. Neuroimage. 68: 49-54. PMID 23228511 DOI: 10.1016/j.neuroimage.2012.11.059  1
2012 Laatikainen LM, Sharp T, Bannerman DM, Harrison PJ, Tunbridge EM. Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition. Journal of Psychopharmacology (Oxford, England). 26: 1561-8. PMID 22815336 DOI: 10.1177/0269881112454228  1
2012 Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. Proceedings of the National Academy of Sciences of the United States of America. 109: 12165-70. PMID 22689948 DOI: 10.1073/pnas.1206118109  1
2012 Matthews PR, Eastwood SL, Harrison PJ. Reduced myelin basic protein and actin-related gene expression in visual cortex in schizophrenia. Plos One. 7: e38211. PMID 22675524 DOI: 10.1371/journal.pone.0038211  1
2012 Pritchett D, Wulff K, Oliver PL, Bannerman DM, Davies KE, Harrison PJ, Peirson SN, Foster RG. Evaluating the links between schizophrenia and sleep and circadian rhythm disruption. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 1061-75. PMID 22569850 DOI: 10.1007/s00702-012-0817-8  1
2012 Tunbridge EM, Huber A, Farrell SM, Stumpenhorst K, Harrison PJ, Walton ME. The role of catechol-O-methyltransferase in reward processing and addiction. Cns & Neurological Disorders Drug Targets. 11: 306-23. PMID 22483300  1
2012 Farrell SM, Tunbridge EM, Braeutigam S, Harrison PJ. COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition. Biological Psychiatry. 71: 538-44. PMID 22364739 DOI: 10.1016/j.biopsych.2011.12.023  1
2012 Cousijn H, Rijpkema M, Harteveld A, Harrison PJ, Fernández G, Franke B, Arias-Vásquez A. Schizophrenia risk gene ZNF804A does not influence macroscopic brain structure: an MRI study in 892 volunteers. Molecular Psychiatry. 17: 1155-7. PMID 22270476 DOI: 10.1038/mp.2011.181  1
2012 Matthews PR, Harrison PJ. A morphometric, immunohistochemical, and in situ hybridization study of the dorsal raphe nucleus in major depression, bipolar disorder, schizophrenia, and suicide. Journal of Affective Disorders. 137: 125-34. PMID 22129767 DOI: 10.1016/j.jad.2011.10.043  1
2012 Deakin IH, Nissen W, Law AJ, Lane T, Kanso R, Schwab MH, Nave KA, Lamsa KP, Paulsen O, Bannerman DM, Harrison PJ. Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 22: 1520-9. PMID 21878485 DOI: 10.1093/cercor/bhr223  1
2012 Harrison PJ, Pritchett D, Stumpenhorst K, Betts JF, Nissen W, Schweimer J, Lane T, Burnet PW, Lamsa KP, Sharp T, Bannerman DM, Tunbridge EM. Genetic mouse models relevant to schizophrenia: taking stock and looking forward. Neuropharmacology. 62: 1164-7. PMID 21864547 DOI: 10.1016/j.neuropharm.2011.08.009  1
2011 Harrison PJ, Baldwin DS, Barnes TR, Burns T, Ebmeier KP, Ferrieer IN, Nutt DJ. No psychiatry without psychopharmacology. The British Journal of Psychiatry : the Journal of Mental Science. 199: 263-5. PMID 22187725 DOI: 10.1192/bjp.bp.111.094334  1
2011 Lyon L, Burnet PW, Kew JN, Corti C, Rawlins JN, Lane T, De Filippis B, Harrison PJ, Bannerman DM. Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2616-28. PMID 21832989 DOI: 10.1038/npp.2011.145  1
2011 Tunbridge EM, Harrison PJ. Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders. Current Topics in Behavioral Neurosciences. 8: 119-40. PMID 21769726 DOI: 10.1007/7854_2010_97  1
2011 Gittins RA, Harrison PJ. A morphometric study of glia and neurons in the anterior cingulate cortex in mood disorder. Journal of Affective Disorders. 133: 328-32. PMID 21497910 DOI: 10.1016/j.jad.2011.03.042  1
2011 Lyon L, Borel M, Carrión M, Kew JN, Corti C, Harrison PJ, Burnet PW, Paulsen O, Rodríguez-Moreno A. Hippocampal mossy fiber long-term depression in Grm2/3 double knockout mice. Synapse (New York, N.Y.). 65: 945-54. PMID 21360593 DOI: 10.1002/syn.20923  1
2011 Kleinman JE, Law AJ, Lipska BK, Hyde TM, Ellis JK, Harrison PJ, Weinberger DR. Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains. Biological Psychiatry. 69: 140-5. PMID 21183009 DOI: 10.1016/j.biopsych.2010.10.032  1
2011 Harrison PJ. Using our brains: the findings, flaws, and future of postmortem studies of psychiatric disorders. Biological Psychiatry. 69: 102-3. PMID 21183008 DOI: 10.1016/j.biopsych.2010.09.008  1
2011 Burnet PW, Anderson PN, Chen L, Nikiforova N, Harrison PJ, Wood MJ. D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNA. Molecular and Cellular Neurosciences. 46: 167-75. PMID 20828614 DOI: 10.1016/j.mcn.2010.08.018  1
2011 Tunbridge EM, Eastwood SL, Harrison PJ. Changed relative to what? Housekeeping genes and normalization strategies in human brain gene expression studies. Biological Psychiatry. 69: 173-9. PMID 20673871 DOI: 10.1016/j.biopsych.2010.05.023  1
2011 Harrison PJ, Lewis DA, Kleinman JE. Neuropathology of Schizophrenia Schizophrenia: Third Edition. 372-392. DOI: 10.1002/9781444327298.ch18  1
2011 Weinberger DR, Harrison PJ. Preface to the 3rd Edition Schizophrenia: Third Edition. XII. DOI: 10.1002/9781444327298  1
2010 Harrison PJ, Laatikainen LM, Tunbridge EM, Eastwood SL. Human brain weight is correlated with expression of the 'housekeeping genes' beta-2-microglobulin (β2M) and TATA-binding protein (TBP). Neuropathology and Applied Neurobiology. 36: 498-504. PMID 20831744 DOI: 10.1111/j.1365-2990.2010.01098.x  1
2010 Eastwood SL, Walker M, Hyde TM, Kleinman JE, Harrison PJ. The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain. Human Molecular Genetics. 19: 2487-96. PMID 20360304 DOI: 10.1093/hmg/ddq130  1
2010 Arabadzisz D, Diaz-Heijtz R, Knuesel I, Weber E, Pilloud S, Dettling AC, Feldon J, Law AJ, Harrison PJ, Pryce CR. Primate early life stress leads to long-term mild hippocampal decreases in corticosteroid receptor expression. Biological Psychiatry. 67: 1106-9. PMID 20132928 DOI: 10.1016/j.biopsych.2009.12.016  1
2010 Sikka P, Walker R, Cockayne R, Wood MJ, Harrison PJ, Burnet PW. D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO). Journal of Neuroscience Research. 88: 1829-40. PMID 20091774 DOI: 10.1002/jnr.22332  1
2010 Eastwood SL, Harrison PJ. Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder. Biological Psychiatry. 67: 1010-6. PMID 20079890 DOI: 10.1016/j.biopsych.2009.12.004  1
2010 Verrall L, Burnet PW, Betts JF, Harrison PJ. The neurobiology of D-amino acid oxidase and its involvement in schizophrenia. Molecular Psychiatry. 15: 122-37. PMID 19786963 DOI: 10.1038/mp.2009.99  1
2009 Deakin IH, Law AJ, Oliver PL, Schwab MH, Nave KA, Harrison PJ, Bannerman DM. Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice. Neuroreport. 20: 1523-8. PMID 19829162 DOI: 10.1097/WNR.0b013e328330f6e7  1
2009 Bristow GC, Lane TA, Walker M, Chen L, Sei Y, Hyde TM, Kleinman JE, Harrison PJ, Eastwood SL. Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype. Brain Research. 1301: 197-206. PMID 19747464 DOI: 10.1016/j.brainres.2009.08.090  1
2009 Eastwood SL, Hodgkinson CA, Harrison PJ. DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release. Molecular Psychiatry. 14: 556-7. PMID 19455170 DOI: 10.1038/mp.2009.13  1
2009 Law AJ, Pei Q, Feldon J, Pryce CR, Harrison PJ. Gene expression in the anterior cingulate cortex and amygdala of adolescent marmoset monkeys following parental separations in infancy. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 761-72. PMID 19102816 DOI: 10.1017/S1461145708009723  1
2009 Law AJ, Pei Q, Walker M, Gordon-Andrews H, Weickert CS, Feldon J, Pryce CR, Harrison PJ. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1381-94. PMID 18615010 DOI: 10.1038/npp.2008.106  1
2008 Lyon L, Kew JN, Corti C, Harrison PJ, Burnet PW. Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice. Synapse (New York, N.Y.). 62: 842-50. PMID 18720515 DOI: 10.1002/syn.20553  1
2008 Craddock N, Antebi D, Attenburrow MJ, Bailey A, Carson A, Cowen P, Craddock B, Eagles J, Ebmeier K, Farmer A, Fazel S, Ferrier N, Geddes J, Goodwin G, Harrison P, et al. Wake-up call for British psychiatry. The British Journal of Psychiatry : the Journal of Mental Science. 193: 6-9. PMID 18700211 DOI: 10.1192/bjp.bp.108.053561  1
2008 Burnet PW, Eastwood SL, Bristow GC, Godlewska BR, Sikka P, Walker M, Harrison PJ. D-amino acid oxidase activity and expression are increased in schizophrenia. Molecular Psychiatry. 13: 658-60. PMID 18560437 DOI: 10.1038/mp.2008.47  1
2008 Harrison PJ, Lyon L, Sartorius LJ, Burnet PW, Lane TA. The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia. Journal of Psychopharmacology (Oxford, England). 22: 308-22. PMID 18541626 DOI: 10.1177/0269881108089818  1
2008 Burnet PW, Hutchinson L, von Hesling M, Gilbert EJ, Brandon NJ, Rutter AR, Hutson PH, Harrison PJ. Expression of D-serine and glycine transporters in the prefrontal cortex and cerebellum in schizophrenia. Schizophrenia Research. 102: 283-94. PMID 18400471 DOI: 10.1016/j.schres.2008.02.009  1
2008 Sartorius LJ, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE, Lipska BK. Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2626-34. PMID 18256595 DOI: 10.1038/sj.npp.1301669  1
2008 Harrison PJ. Metabotropic glutamate receptor agonists for schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 192: 86-7. PMID 18245019 DOI: 10.1192/bjp.bp.107.045088  1
2008 Tunbridge EM, Harrison PJ, Warden DR, Johnston C, Refsum H, Smith AD. Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 996-9. PMID 18189241 DOI: 10.1002/ajmg.b.30700  1
2008 Harrison PJ, Tunbridge EM. Catechol-O-methyltransferase (COMT): a gene contributing to sex differences in brain function, and to sexual dimorphism in the predisposition to psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3037-45. PMID 17805313 DOI: 10.1038/sj.npp.1301543  1
2008 Eastwood SL, Harrison PJ. Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 933-45. PMID 17507910 DOI: 10.1038/sj.npp.1301457  1
2008 Craddock N, Antebi D, Attenburrow MJ, Bailey T, Carson A, Cowen P, Craddock B, Eagles J, Ebmeier K, Farmer A, Fazel S, Ferrier N, Geddes J, Goodwin G, Harrison P, et al. Authors' reply British Journal of Psychiatry. 193: 517. DOI: 10.1192/bjp.193.6.517  1
2007 Harrison PJ. Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1. Novartis Foundation Symposium. 288: 246-55; discussion 2. PMID 18494263 DOI: 10.1002/9780470994030.ch17  1
2007 Verrall L, Walker M, Rawlings N, Benzel I, Kew JN, Harrison PJ, Burnet PW. d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. The European Journal of Neuroscience. 26: 1657-69. PMID 17880399 DOI: 10.1111/j.1460-9568.2007.05769.x  1
2007 Tan W, Wang Y, Gold B, Chen J, Dean M, Harrison PJ, Weinberger DR, Law AJ. Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia. The Journal of Biological Chemistry. 282: 24343-51. PMID 17565985 DOI: 10.1074/jbc.M702953200  1
2007 Sisodiya S, Cross JH, Blümcke I, Chadwick D, Craig J, Crino PB, Debenham P, Delanty N, Elmslie F, Gardiner M, Golden J, Goldstein D, Greenberg DA, Guerrini R, Hanna M, ... ... Harrison P, et al. Genetics of epilepsy: epilepsy research foundation workshop report. Epileptic Disorders : International Epilepsy Journal With Videotape. 9: 194-236. PMID 17525034 DOI: 10.1684/epd.2007.0107  1
2007 Harrison PJ. Schizophrenia susceptibility genes and neurodevelopment. Biological Psychiatry. 61: 1119-20. PMID 17481418 DOI: 10.1016/j.biopsych.2007.02.021  1
2007 Tunbridge EM, Lane TA, Harrison PJ. Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 834-9. PMID 17477346 DOI: 10.1002/ajmg.b.30539  1
2007 Pooley EC, Fineberg N, Harrison PJ. The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis. Molecular Psychiatry. 12: 556-61. PMID 17264842 DOI: 10.1038/sj.mp.4001951  1
2007 Eastwood SL, Lyon L, George L, Andrieux A, Job D, Harrison PJ. Altered expression of synaptic protein mRNAs in STOP (MAP6) mutant mice. Journal of Psychopharmacology (Oxford, England). 21: 635-44. PMID 17050659 DOI: 10.1177/0269881106068825  1
2007 Tunbridge EM, Weickert CS, Kleinman JE, Herman MM, Chen J, Kolachana BS, Harrison PJ, Weinberger DR. Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cerebral Cortex (New York, N.Y. : 1991). 17: 1206-12. PMID 16835293 DOI: 10.1093/cercor/bhl032  1
2007 Harrison PJ. The genetics of schizophrenia: Recent progress and lessons for epilepsy Epileptic Disorders. 9: 203-204.  1
2006 Harrison PJ, West VA. Six degrees of separation: on the prior probability that schizophrenia susceptibility genes converge on synapses, glutamate and NMDA receptors. Molecular Psychiatry. 11: 981-3. PMID 17063182 DOI: 10.1038/sj.mp.4001886  1
2006 Eastwood SL, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Synaptophysin protein and mRNA expression in the human hippocampal formation from birth to old age. Hippocampus. 16: 645-54. PMID 16807900 DOI: 10.1002/hipo.20194  1
2006 Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 6747-52. PMID 16618933 DOI: 10.1073/pnas.0602002103  1
2006 Eastwood SL, Harrison PJ. Cellular basis of reduced cortical reelin expression in schizophrenia. The American Journal of Psychiatry. 163: 540-2. PMID 16513881 DOI: 10.1176/appi.ajp.163.3.540  1
2006 Tunbridge EM, Harrison PJ, Weinberger DR. Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biological Psychiatry. 60: 141-51. PMID 16476412 DOI: 10.1016/j.biopsych.2005.10.024  1
2006 Harrison PJ, Law AJ. Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biological Psychiatry. 60: 132-40. PMID 16442083 DOI: 10.1016/j.biopsych.2005.11.002  1
2006 Sartorius LJ, Nagappan G, Lipska BK, Lu B, Sei Y, Ren-Patterson R, Li Z, Weinberger DR, Harrison PJ. Alternative splicing of human metabotropic glutamate receptor 3. Journal of Neurochemistry. 96: 1139-48. PMID 16417579 DOI: 10.1111/j.1471-4159.2005.03609.x  1
2006 Cullen TJ, Walker MA, Eastwood SL, Esiri MM, Harrison PJ, Crow TJ. Anomalies of asymmetry of pyramidal cell density and structure in dorsolateral prefrontal cortex in schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 188: 26-31. PMID 16388066 DOI: 10.1192/bjp.bp.104.008169  1
2006 Tunbridge EM, Weinberger DR, Harrison PJ. A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype. Molecular Psychiatry. 11: 116-7. PMID 16247488 DOI: 10.1038/sj.mp.4001767  1
2005 Eastwood SL, Salih T, Harrison PJ. Differential expression of calcineurin A subunit mRNA isoforms during rat hippocampal and cerebellar development. The European Journal of Neuroscience. 22: 3017-24. PMID 16367768 DOI: 10.1111/j.1460-9568.2005.04518.x  1
2005 McCabe DJH, Harrison P, Mackie IJ, Sidhu PS, Purdy G, Lawrie AS, Watt H, Machin SJ, Brown MM. Increased platelet count and leucocyte-platelet complex formation in acute symptomatic compared with asymptomatic severe carotid stenosis Journal of Neurology, Neurosurgery and Psychiatry. 76: 1249-1254. PMID 16107361 DOI: 10.1136/jnnp.2004.051003  1
2005 Eastwood SL, Harrison PJ. Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia. Schizophrenia Research. 79: 181-8. PMID 16076548 DOI: 10.1016/j.schres.2005.07.001  1
2005 Syed A, Chatfield M, Matthews F, Harrison P, Brayne C, Esiri MM. Depression in the elderly: pathological study of raphe and locus ceruleus. Neuropathology and Applied Neurobiology. 31: 405-13. PMID 16008824 DOI: 10.1111/j.1365-2990.2005.00662.x  1
2005 Sodhi MS, Airey DC, Lambert W, Burnet PW, Harrison PJ, Sanders-Bush E. A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Molecular Pharmacology. 68: 711-9. PMID 15917433 DOI: 10.1124/mol.105.014134  1
2005 Eastwood SL, Burnet PW, Harrison PJ. Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia. Biological Psychiatry. 57: 702-10. PMID 15820226 DOI: 10.1016/j.biopsych.2004.12.029  0.8
2005 Eastwood SL, Harrison PJ. Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophrenia Research. 73: 159-72. PMID 15653259 DOI: 10.1016/j.schres.2004.05.010  0.76
2005 Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DC, Hinds MG. Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands. The Journal of Biological Chemistry. 280: 4738-44. PMID 15550399 DOI: 10.1074/jbc.M411434200  0.36
2005 Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Molecular Psychiatry. 10: 40-68; image 5. PMID 15263907 DOI: 10.1038/sj.mp.4001558  0.48
2004 Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ. Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. The American Journal of Psychiatry. 161: 1848-55. PMID 15465982 DOI: 10.1176/appi.ajp.161.10.1848  1
2004 Law AJ, Shannon Weickert C, Hyde TM, Kleinman JE, Harrison PJ. Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience. 127: 125-36. PMID 15219675 DOI: 10.1016/j.neuroscience.2004.04.026  1
2004 Tunbridge EM, Bannerman DM, Sharp T, Harrison PJ. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5331-5. PMID 15190105 DOI: 10.1523/JNEUROSCI.1124-04.2004  1
2004 Law AJ, Hutchinson LJ, Burnet PW, Harrison PJ. Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex. Journal of Neuroscience Research. 76: 376-82. PMID 15079866 DOI: 10.1002/jnr.20092  1
2004 Pooley EC, Fairburn CG, Cooper Z, Sodhi MS, Cowen PJ, Harrison PJ. A 5-HT2C receptor promoter polymorphism (HTR2C - 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 126: 124-7. PMID 15048662 DOI: 10.1002/ajmg.b.20143  1
2004 Burnet PW, Eastwood SL, Harrison PJ. Laser-assisted microdissection: methods for the molecular analysis of psychiatric disorders at a cellular resolution. Biological Psychiatry. 55: 107-11. PMID 14732588  0.8
2004 Tunbridge E, Burnet PW, Sodhi MS, Harrison PJ. Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression. Synapse (New York, N.Y.). 51: 112-8. PMID 14618678 DOI: 10.1002/syn.10286  1
2003 Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Changes in NMDA receptor subunit mRNAs and cyclophilin mRNA during development of the human hippocampus. Annals of the New York Academy of Sciences. 1003: 426-30. PMID 14684479 DOI: 10.1196/annals.1300.043  1
2003 Harrison PJ, Law AJ, Eastwood SL. Glutamate receptors and transporters in the hippocampus in schizophrenia. Annals of the New York Academy of Sciences. 1003: 94-101. PMID 14684437 DOI: 10.1196/annals.1300.006  1
2003 Law AJ, Harrison PJ. The distribution and morphology of prefrontal cortex pyramidal neurons identified using anti-neurofilament antibodies SMI32, N200 and FNP7. Normative data and a comparison in subjects with schizophrenia, bipolar disorder or major depression. Journal of Psychiatric Research. 37: 487-99. PMID 14563380 DOI: 10.1016/S0022-3956(03)00075-X  1
2003 Harrison PJ, Freemantle N, Geddes JR. Meta-analysis of brain weight in schizophrenia. Schizophrenia Research. 64: 25-34. PMID 14511798  0.56
2003 Harris LW, Sharp T, Gartlon J, Jones DN, Harrison PJ. Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism. The European Journal of Neuroscience. 18: 1706-10. PMID 14511349 DOI: 10.1046/j.1460-9568.2003.02902.x  1
2003 Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. The European Journal of Neuroscience. 18: 1197-205. PMID 12956718 DOI: 10.1046/j.1460-9568.2003.02850.x  1
2003 Eastwood SL, Harrison PJ. Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis. Molecular Psychiatry. 8: 769, 821-31. PMID 12931209 DOI: 10.1038/sj.mp.4001371  0.76
2003 Eastwood SL, Law AJ, Everall IP, Harrison PJ. The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology. Molecular Psychiatry. 8: 148-55. PMID 12610647 DOI: 10.1038/sj.mp.4001233  1
2002 East SZ, Burnet PW, Kerwin RW, Harrison PJ. An RT-PCR study of 5-HT(6) and 5-HT(7) receptor mRNAs in the hippocampal formation and prefrontal cortex in schizophrenia. Schizophrenia Research. 57: 15-26. PMID 12165372 DOI: 10.1016/S0920-9964(01)00323-1  1
2002 East SZ, Burnet PW, Leslie RA, Roberts JC, Harrison PJ. 5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585. Synapse (New York, N.Y.). 45: 191-9. PMID 12112397 DOI: 10.1002/syn.10097  0.8
2002 Meller R, Harrison PJ, Sharp T. Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells. European Journal of Pharmacology. 445: 13-9. PMID 12065189 DOI: 10.1016/S0014-2999(02)01718-1  1
2002 Roberts JC, Reavill C, East SZ, Harrison PJ, Patel S, Routledge C, Leslie RA. The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585. Brain Research. 934: 49-57. PMID 11937069 DOI: 10.1016/S0006-8993(02)02360-0  1
2002 Meller R, Harrison PJ, Elliott JM, Sharp T. In vitro evidence that 5-hydroxytryptamine increases efflux of glial glutamate via 5-HT(2A) receptor activation. Journal of Neuroscience Research. 67: 399-405. PMID 11813245 DOI: 10.1002/jnr.10126  1
2001 Harrison PJ, Eastwood SL. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia. Hippocampus. 11: 508-19. PMID 11732704 DOI: 10.1002/hipo.1067  0.76
2001 Eastwood SL, Harrison PJ. Synaptic pathology in the anterior cingulate cortex in schizophrenia and mood disorders. A review and a Western blot study of synaptophysin, GAP-43 and the complexins. Brain Research Bulletin. 55: 569-78. PMID 11576753  0.76
2001 Eastwood SL, Cotter D, Harrison PJ. Cerebellar synaptic protein expression in schizophrenia. Neuroscience. 105: 219-29. PMID 11483314  0.76
2001 Sodhi MS, Burnet PW, Makoff AJ, Kerwin RW, Harrison PJ. RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia. Molecular Psychiatry. 6: 373-9. PMID 11443520 DOI: 10.1038/sj.mp.4000920  1
2001 Highley JR, Walker MA, Esiri MM, McDonald B, Harrison PJ, Crow TJ. Schizophrenia and the frontal lobes: post-mortem stereological study of tissue volume. The British Journal of Psychiatry : the Journal of Mental Science. 178: 337-43. PMID 11282813  0.32
2001 Burnet PW, Miller R, Lewis LJ, Pei Q, Sharp T, Harrison PJ. Electroconvulsive shock increases tachykinin NK(1) receptors, but not the encoding mRNA, in rat cortex. European Journal of Pharmacology. 413: 213-9. PMID 11226395 DOI: 10.1016/S0014-2999(01)00777-4  1
2000 Harrison PJ. Serotonin 2A receptor polymorphisms and [(3)H]Ketanserin binding. The American Journal of Psychiatry. 157: 1710-1. PMID 11007744 DOI: 10.1176/appi.ajp.157.10.1710  1
2000 Rabiner EA, Gunn RN, Castro ME, Sargent PA, Cowen PJ, Koepp MJ, Meyer JH, Bench CJ, Harrison PJ, Pazos A, Sharp T, Grasby PM. beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 285-93. PMID 10942852 DOI: 10.1016/S0893-133X(00)00109-3  1
2000 Castro ME, Harrison PJ, Pazos A, Sharp T. Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain. Journal of Neurochemistry. 75: 755-62. PMID 10899952 DOI: 10.1046/j.1471-4159.2000.0750755.x  1
2000 Eastwood SL, Harrison PJ. Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs. Molecular Psychiatry. 5: 425-32. PMID 10889554  0.76
2000 Eastwood SL, Harrison PJ. Complexin I and II mRNAs in the human hippocampus. Molecular Psychiatry. 5: 341. PMID 10889540  0.76
2000 Eastwood SL, Burnet PW, Harrison PJ. Expression of complexin I and II mRNAs and their regulation by antipsychotic drugs in the rat forebrain. Synapse (New York, N.Y.). 36: 167-77. PMID 10819897 DOI: 10.1002/(SICI)1098-2396(20000601)36:3<167::AID-SYN2>3.0.CO;2-D  0.8
2000 Eastwood SL, Cairns NJ, Harrison PJ. Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex. The British Journal of Psychiatry : the Journal of Mental Science. 176: 236-42. PMID 10755070  0.76
2000 Burnet PW, Harrison PJ. Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia. Biological Psychiatry. 47: 80-3. PMID 10650452  0.8
1999 Burnet PW, Sharp T, LeCorre SM, Harrison PJ. Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock. Neuroscience Letters. 277: 79-82. PMID 10624814  0.92
1999 Eastwood SL, Harrison PJ. Detection and quantification of hippocampal synaptophysin messenger RNA in schizophrenia using autoclaved, formalin-fixed, paraffin wax-embedded sections. Neuroscience. 93: 99-106. PMID 10430474  0.76
1999 Burnet PW, Smith KA, Cowen PJ, Fairburn CG, Harrison PJ. Allelic variation of the 5-HT2C receptor (HTR2C) in bulimia nervosa and binge eating disorder. Psychiatric Genetics. 9: 101-4. PMID 10412190  0.8
1998 Eastwood SL, Harrison PJ. Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia. Neuroscience. 86: 437-48. PMID 9881859  0.76
1998 Harrison PJ, Eastwood SL. Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia. Lancet. 352: 1669-73. PMID 9853440 DOI: 10.1016/S0140-6736(98)03341-8  0.76
1998 Heffernan JM, Eastwood SL, Nagy Z, Sanders MW, McDonald B, Harrison PJ. Temporal cortex synaptophysin mRNA is reduced in Alzheimer's disease and is negatively correlated with the severity of dementia. Experimental Neurology. 150: 235-9. PMID 9527892 DOI: 10.1006/exnr.1997.6772  1
1997 Geddes JR, Harrison PJ. Closing the gap between research and practice. The British Journal of Psychiatry : the Journal of Mental Science. 171: 220-5. PMID 9337970  0.56
1997 Harrison PJ, Burnet PW, Falkai P, Bogerts B, Eastwood SL. Gene expression and neuronal activity in schizophrenia: a study of polyadenylated mRNA in the hippocampal formation and cerebral cortex. Schizophrenia Research. 26: 93-102. PMID 9323338  0.8
1997 Burnet PW, Harrison PJ, Goodwin GM, Battersby S, Ogilvie AD, Olesen J, Russell MB. Allelic variation in the serotonin 5-HT2C receptor gene and migraine. Neuroreport. 8: 2651-3. PMID 9295094  0.8
1997 Kouzmenko AP, Hayes WL, Pereira AM, Dean B, Burnet PW, Harrison PJ. 5-HT2A receptor polymorphism and steady state receptor expression in schizophrenia. Lancet. 349: 1815. PMID 9269223 DOI: 10.1016/S0140-6736(05)61695-9  0.8
1997 Le Corre SM, Burnet PW, Meller R, Sharp T, Harrison PJ. Critical issues in the antisense inhibition of brain gene expression in vivo: experiences targetting the 5-HT1A receptor. Neurochemistry International. 31: 349-62. PMID 9246678  0.92
1997 Eastwood SL, Heffernan J, Harrison PJ. Chronic haloperidol treatment differentially affects the expression of synaptic and neuronal plasticity-associated genes. Molecular Psychiatry. 2: 322-9. PMID 9246673  0.76
1997 Le Corre S, Sharp T, Young AH, Harrison PJ. Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy. Psychopharmacology. 130: 368-74. PMID 9160853  0.92
1997 Burnet PW, Eastwood SL, Harrison PJ. [3H]WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with [3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia. Neurochemistry International. 30: 565-74. PMID 9152998  0.8
1997 Porter RH, Eastwood SL, Harrison PJ. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Research. 751: 217-31. PMID 9099808  0.76
1997 Harrison PJ, Burnet PW. The 5-HT2A (serotonin2A) receptor gene in the aetiology, pathophysiology and pharmacotherapy of schizophrenia. Journal of Psychopharmacology (Oxford, England). 11: 18-20. PMID 9097886  0.8
1997 Eastwood SL, Kerwin RW, Harrison PJ. Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia. Biological Psychiatry. 41: 636-43. PMID 9066986 DOI: 10.1016/S0006-3223(96)00220-X  1
1997 Eastwood SL, Burnet PW, Harrison PJ. GluR2 glutamate receptor subunit flip and flop isoforms are decreased in the hippocampal formation in schizophrenia: a reverse transcriptase-polymerase chain reaction (RT-PCR) study. Brain Research. Molecular Brain Research. 44: 92-8. PMID 9030702  0.8
1996 Harrison PJ, Wighton-Benn WH, Heffernan JM, Sanders MW, Pearson RC. Amyloid precursor protein mRNAs in Alzheimer's disease. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 409-15. PMID 9117555 DOI: 10.1006/neur.1996.0055  1
1996 Porter RH, Burnet PW, Eastwood SL, Harrison PJ. Contrasting effects of electroconvulsive shock on mRNAs encoding the high affinity kainate receptor subunits (KA1 and KA2) and cyclophilin in the rat. Brain Research. 710: 97-102. PMID 8963683  0.8
1996 Burnet PW, Eastwood SL, Harrison PJ. 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 442-55. PMID 8914117 DOI: 10.1016/S0893-133X(96)00053-X  0.8
1996 Eastwood SL, Porter RH, Harrison PJ. The effect of chronic haloperidol treatment on glutamate receptor subunit (GluR1, GluR2, KA1, KA2, NR1) mRNAs and glutamate binding protein mRNA in rat forebrain. Neuroscience Letters. 212: 163-6. PMID 8843098  0.76
1996 McGowan S, Eastwood SL, Mead A, Burnet PW, Smith C, Flanigan TP, Harrison PJ. Hippocampal and cortical G protein (Gs alpha, G(o) alpha and Gi2 alpha) mRNA expression after electroconvulsive shock or lithium carbonate treatment. European Journal of Pharmacology. 306: 249-55. PMID 8813638  0.8
1996 Burnet PW, Chen CP, McGowan S, Franklin M, Harrison PJ. The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain. Neuroscience. 73: 531-40. PMID 8783268  0.8
1996 Harrison PJ, Geddes JR. Schizophrenia and the 5-HT2A receptor gene. Lancet. 347: 1274. PMID 8622497  0.56
1995 Harrison PJ, Geddes JR. Psychiatry. Molecules, mice, and meta-analyses. Lancet. 346: s19. PMID 9454036  0.56
1995 Harrison PJ, Heath PR, Eastwood SL, Burnet PW, McDonald B, Pearson RC. The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins. Neuroscience Letters. 200: 151-4. PMID 9064599  0.8
1995 Eastwood SL, Harrison PJ. Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography. Neuroscience. 69: 339-43. PMID 8552231  0.76
1995 Zaidel DW, Esiri MM, Eastwood SL, Harrison PJ. Asymmetrical hippocampal circuitry and schizophrenia. Lancet. 345: 656-7. PMID 7898213  0.76
1995 Burnet PW, Eastwood SL, Lacey K, Harrison PJ. The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain. Brain Research. 676: 157-68. PMID 7796165 DOI: 10.1016/0006-8993(95)00104-X  1
1995 Burnet PW, Mead A, Eastwood SL, Lacey K, Harrison PJ, Sharp T. Repeated ECS differentially affects rat brain 5-HT1A and 5-HT2A receptor expression. Neuroreport. 6: 901-4. PMID 7612879  1
1995 Eastwood SL, McDonald B, Burnet PW, Beckwith JP, Kerwin RW, Harrison PJ. Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. Brain Research. Molecular Brain Research. 29: 211-23. PMID 7609609 DOI: 10.1016/0169-328X(94)00247-C  1
1995 Burnet PW, Harrison PJ. Genetic variation of the 5-HT2A receptor and response to clozapine. Lancet. 346: 909. PMID 7564705  0.8
1995 Eastwood SL, Burnet PW, Harrison PJ. Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia. Neuroscience. 66: 309-19. PMID 7477874  0.8
1994 Eastwood SL, Story P, Burnet PW, Heath P, Harrison PJ. Differential changes in glutamate receptor subunit messenger RNAs in rat brain after haloperidol treatment. Journal of Psychopharmacology (Oxford, England). 8: 196-203. PMID 22298625 DOI: 10.1177/026988119400800402  0.8
1994 Harrison PJ, Barton AJ, Procter AW, Bowen DM, Pearson RC. The effects of Alzheimer's disease, other dementias, and premortem course on beta-amyloid precursor protein messenger RNA in frontal cortex. Journal of Neurochemistry. 62: 635-44. PMID 8294927  1
1994 Eastwood SL, Burnet PW, Harrison PJ. Striatal synaptophysin expression and haloperidol-induced synaptic plasticity. Neuroreport. 5: 677-80. PMID 8199336  0.8
1994 Harrison PJ, Burnet PW. Antisense as an explanatory, experimental and therapeutic tool for psychiatric disorders. Psychological Medicine. 24: 275-9. PMID 8084926  0.8
1994 Eastwood SL, Burnet PW, McDonald B, Clinton J, Harrison PJ. Synaptophysin gene expression in human brain: a quantitative in situ hybridization and immunocytochemical study. Neuroscience. 59: 881-92. PMID 8058126 DOI: 10.1016/0306-4522(94)90292-5  0.76
1994 Eastwood SL, Burnet PW, Beckwith J, Kerwin RW, Harrison PJ. AMPA glutamate receptors and their flip and flop mRNAs in human hippocampus. Neuroreport. 5: 1325-8. PMID 7919190  1
1994 Procter AW, Francis PT, Holmes C, Webster MT, Qume M, Stratmann GC, Doshi R, Mann DM, Harrison PJ, Pearson RC. beta-Amyloid precursor protein isoforms show correlations with neurones but not with glia of demented subjects. Acta Neuropathologica. 88: 545-52. PMID 7879601 DOI: 10.1007/s004010050197  1
1994 Burnet PW, Eastwood SL, Harrison PJ. Detection and quantitation of 5-HT1A and 5-HT2A receptor mRNAs in human hippocampus using a reverse transcriptase-polymerase chain reaction (RT-PCR) technique and their correlation with binding site densities and age. Neuroscience Letters. 178: 85-9. PMID 7529388  0.8
1991 Harrison PJ, Barton AJ, Najlerahim A, McDonald B, Pearson RC. Regional and neuronal reductions of polyadenylated messenger RNA in Alzheimer's disease. Psychological Medicine. 21: 855-66. PMID 1685790  0.32
1991 Harrison PJ, Barton AJ, Najlerahim A, McDonald B, Pearson RC. Increased muscarinic receptor messenger RNA in Alzheimer's disease temporal cortex demonstrated by in situ hybridization histochemistry. Brain Research. Molecular Brain Research. 9: 15-21. PMID 1673214  0.32
1991 Harrison PJ, McLaughlin D, Kerwin RW. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet. 337: 450-2. PMID 1671470 DOI: 10.1016/0140-6736(91)93392-M  1
1991 Harrison PJ, Barton AJ, McDonald B, Pearson RC. Alzheimer's disease: specific increases in a G protein subunit (Gs alpha) mRNA in hippocampal and cortical neurons. Brain Research. Molecular Brain Research. 10: 71-81. PMID 1647485  0.32
1990 Barton AJ, Harrison PJ, Najlerahim A, Heffernan J, McDonald B, Robinson JR, Davies DC, Harrison WJ, Mitra P, Hardy JA. Increased tau messenger RNA in Alzheimer's disease hippocampus. The American Journal of Pathology. 137: 497-502. PMID 2119143  1
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