Shinichi Kano, MD, PhD - Publications

Affiliations: 
2002-2007 Immunology The University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 
 2007-2018 Psychiatry and Behavioral Sciences Johns Hopkins University, Baltimore, MD 
 2019- Psychiatry and Behavioral Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Leitzel O, Francis-Oliveira J, Khedr SM, Ariste L, Robel S, Kano SI, Arrant A, Niwa M. Adolescent stress accelerates postpartum novelty recognition impairment in 5xFAD mice. Frontiers in Neuroscience. 18: 1366199. PMID 38812977 DOI: 10.3389/fnins.2024.1366199  0.634
2024 Niwa M, Lockhart S, Wood DJ, Yang K, Francis-Oliveira J, Kin K, Ahmed A, Wand GS, Kano SI, Payne JL, Sawa A. Prolonged HPA axis dysregulation in postpartum depression associated with adverse early life experiences: A cross-species translational study. Nature. Mental Health. 2: 593-604. PMID 38736646 DOI: 10.1038/s44220-024-00217-1  0.684
2023 Kin K, Francis-Oliveira J, Kano SI, Niwa M. Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway in mice. Nature Communications. 14: 2975. PMID 37221211 DOI: 10.1038/s41467-023-38799-6  0.669
2023 Zhu X, Sakamoto S, Ishii C, Smith MD, Ito K, Obayashi M, Unger L, Hasegawa Y, Kurokawa S, Kishimoto T, Li H, Hatano S, Wang TH, Yoshikai Y, Kano SI, et al. Dectin-1 signaling on colonic γδ T cells promotes psychosocial stress responses. Nature Immunology. PMID 36941398 DOI: 10.1038/s41590-023-01447-8  0.54
2023 Kin K, Kano SI, Niwa M. Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway. Biorxiv : the Preprint Server For Biology. PMID 36711960 DOI: 10.1101/2023.01.03.522598  0.669
2023 Matoba K, Dohi E, Choi EY, Kano SI. Glutathione S-transferases Control astrocyte activation and neuronal health during neuroinflammation. Frontiers in Molecular Biosciences. 9: 1080140. PMID 36685285 DOI: 10.3389/fmolb.2022.1080140  0.792
2022 Hayes LN, An K, Carloni E, Li F, Vincent E, Trippaers C, Paranjpe M, Dölen G, Goff LA, Ramos A, Kano SI, Sawa A. Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry. Nature. PMID 36171283 DOI: 10.1038/s41586-022-05274-z  0.79
2021 Sakamoto S, Mallah D, Medeiros DJ, Dohi E, Imai T, Rose IV, Matoba K, Zhu X, Kamiya A, Kano SI. Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice. Febs Open Bio. PMID 34043886 DOI: 10.1002/2211-5463.13204  0.735
2021 Kano SI, Yang K, Sawa A. Making Sense of Extracellular Vesicles in Body Fluids: Promise and Challenge. Schizophrenia Bulletin. PMID 33748856 DOI: 10.1093/schbul/sbab009  0.306
2020 Sagata N, Kano SI, Ohgidani M, Inamine S, Sakai Y, Kato H, Masuda K, Nakahara T, Nakahara-Kido M, Ohga S, Furue M, Sawa A, Kanba S, Kato TA. Forskolin rapidly enhances neuron-like morphological change of directly induced-neuronal cells from neurofibromatosis type 1 patients. Neuropsychopharmacology Reports. PMID 33037790 DOI: 10.1002/npr2.12144  0.493
2019 Kano SI, Sawa A. Reply to Brune M and Theiss C: Remaining questions in the relationship between T. gondii infection and major mental illness. Molecular Psychiatry. PMID 31641217 DOI: 10.1038/s41380-019-0556-4  0.34
2019 Yang K, Kondo MA, Jaaro-Peled H, Cash-Padgett T, Kano SI, Ishizuka K, Pevsner J, Tomoda T, Sawa A, Niwa M. The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood. Schizophrenia Research. PMID 31204062 DOI: 10.1016/J.Schres.2019.05.032  0.786
2019 Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A. Glutathione -transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. Science Signaling. 12. PMID 30783009 DOI: 10.1126/Scisignal.Aar2124  0.751
2018 Kano SI, Dohi E, Rose IVL. Extracellular Vesicles for Research on Psychiatric Disorders. Schizophrenia Bulletin. PMID 30239909 DOI: 10.1093/Schbul/Sby127  0.741
2018 Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, et al. Host-parasite interaction associated with major mental illness. Molecular Psychiatry. PMID 30127472 DOI: 10.1038/S41380-018-0217-Z  0.769
2018 Akamine S, Sagata N, Sakai Y, Kato TA, Nakahara T, Matsushita Y, Togao O, Hiwatashi A, Sanefuji M, Ishizaki Y, Torisu H, Saitsu H, Matsumoto N, Hara T, Sawa A, ... Kano S, et al. Early-onset epileptic encephalopathy and severe developmental delay in an association with de novo double mutations inand. Epilepsia Open. 3: 81-85. PMID 29588991 DOI: 10.1002/epi4.12085  0.446
2018 Fukudome D, Hayes LN, Faust TE, Foss CA, Kondo MA, Lee BJ, Saito A, Kano SI, Coughlin JM, Kamiya A, Pomper MG, Sawa A, Niwa M. Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances. Schizophrenia Research. PMID 29398205 DOI: 10.1016/J.Schres.2018.01.015  0.762
2017 Dohi E, Choi EY, Rose IVL, Murata AS, Chow S, Niwa M, Kano SI. Behavioral Changes in Mice Lacking Interleukin-33. Eneuro. 4. PMID 29379874 DOI: 10.1523/ENEURO.0147-17.2017  0.754
2017 Sagata N, Kato TA, Kano SI, Ohgidani M, Shimokawa N, Sato-Kasai M, Hayakawa K, Kuwano N, Wilson AM, Ishizuka K, Kato S, Nakahara T, Nakahara-Kido M, Setoyama D, Sakai Y, et al. Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study. Scientific Reports. 7: 13905. PMID 29066822 DOI: 10.1038/S41598-017-14440-7  0.628
2016 Niwa M, Lee RS, Tanaka T, Okada K, Kano SI, Sawa A. A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons. Human Molecular Genetics. PMID 26908623 DOI: 10.1093/Hmg/Ddw019  0.738
2016 Lo B, Chang D, Kano S. Alternative Human Cell Models for Neuropsychiatric Research: Induced Neuronal Cells, Olfactory Epithelium, and Related Resources Handbook of Behavioral Neuroscience. 23: 407-422. DOI: 10.1016/B978-0-12-800981-9.00024-9  0.392
2015 Passeri E, Jones-Brando L, Bordón C, Sengupta S, Wilson AM, Primerano A, Rapoport JL, Ishikuza K, Kano SI, Yolken RH, Sawa A. Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls. Microbes and Infection / Institut Pasteur. PMID 26432947 DOI: 10.1016/J.Micinf.2015.09.023  0.5
2015 Passeri E, Wilson AM, Primerano A, Kondo MA, Sengupta S, Srivastava R, Koga M, Obie C, Zandi PP, Goes FS, Valle D, Rapoport JL, Sawa A, Kano SI, Ishizuka K. Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities. Neuroscience Research. PMID 26260244 DOI: 10.1016/J.Neures.2015.07.011  0.773
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300  0.781
2014 Patil SA, Kano S, Sawa A, Maegawa GH. Using small molecules to increase the direct conversion of culture fibroblasts from MPS II patients into induced-neuronal (iN) cells Molecular Genetics and Metabolism. 111: S84-S85. DOI: 10.1016/J.Ymgme.2013.12.202  0.475
2013 Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/J.Neures.2013.09.010  0.607
2013 Tezuka T, Tamura M, Kondo MA, Sakaue M, Okada K, Takemoto K, Fukunari A, Miwa K, Ohzeki H, Kano S, Yasumatsu H, Sawa A, Kajii Y. Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis. Neurobiology of Disease. 59: 63-8. PMID 23867234 DOI: 10.1016/j.nbd.2013.07.003  0.732
2013 Kondo MA, Tajinda K, Colantuoni C, Hiyama H, Seshadri S, Huang B, Pou S, Furukori K, Hookway C, Jaaro-Peled H, Kano SI, Matsuoka N, Harada K, Ni K, Pevsner J, et al. Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control. Translational Psychiatry. 3: e243. PMID 23549417 DOI: 10.1038/Tp.2013.19  0.783
2013 Mor E, Kano S, Colantuoni C, Sawa A, Navon R, Shomron N. MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiology of Disease. 55: 1-10. PMID 23542694 DOI: 10.1016/J.Nbd.2013.03.011  0.486
2013 Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano S, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 61: 679-93. PMID 23382131 DOI: 10.1002/Glia.22461  0.493
2013 Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science (New York, N.Y.). 339: 335-9. PMID 23329051 DOI: 10.1126/Science.1226931  0.768
2013 Kano S, Colantuoni C, Han F, Zhou Z, Yuan Q, Wilson A, Takayanagi Y, Lee Y, Rapoport J, Eaton W, Cascella N, Ji H, Goldman D, Sawa A. Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia. Molecular Psychiatry. 18: 740-2. PMID 22925834 DOI: 10.1038/Mp.2012.120  0.497
2013 Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Molecular Psychiatry. 18: 10-1. PMID 22349781 DOI: 10.1038/Mp.2012.6  0.747
2012 Mouri A, Koseki T, Narusawa S, Niwa M, Mamiya T, Kano S, Sawa A, Nabeshima T. Mouse strain differences in phencyclidine-induced behavioural changes. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 767-79. PMID 21733237 DOI: 10.1017/S146114571100085X  0.677
2011 Kano S, Nwulia E, Niwa M, Chen Y, Sawa A, Cascella N. Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia. Neuroscience Research. 71: 289-93. PMID 21801761 DOI: 10.1016/J.Neures.2011.07.1818  0.737
2011 Ozeki Y, Pickard BS, Kano S, Malloy MP, Zeledon M, Sun DQ, Fujii K, Wakui K, Shirayama Y, Fukushima Y, Kunugi H, Hashimoto K, Muir WJ, Blackwood DH, Sawa A. A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression. Neuroscience Research. 69: 154-60. PMID 20955740 DOI: 10.1016/J.Neures.2010.10.003  0.768
2010 Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/Pnas.0909284107  0.794
2010 Ishizuka K, Kano S, Colantuoni C, Schretlen D, Cascella NG, Sawa A. A translational approach for schizophrenia: Systematic cell/tissue engineering combined with detailed phenotypic characterization and molecular brain imaging Neuroscience Research. 68: e18. DOI: 10.1016/J.Neures.2010.07.315  0.629
2010 Horiuchi Y, Ishii S, Kano S, Ishizuka K, Okada Y, Colantuoni C, Valle D, Cascella NG, Akamatsu W, Sawa A, Okano H. Generation of induced pluripotent stem cells from patients with schizophrenia Neuroscience Research. 68: e314. DOI: 10.1016/J.Neures.2010.07.1395  0.621
2008 Kano S, Sato K, Morishita Y, Vollstedt S, Kim S, Bishop K, Honda K, Kubo M, Taniguchi T. The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells. Nature Immunology. 9: 34-41. PMID 18059273 DOI: 10.1038/ni1538  0.447
2007 Kano S, Sato K, Vollstedt S, Kim S, Honda K, Kubo M, Taniguchi T. 70 Requirement of IL-12RB1 Induction by IRF1 for IL-12 Responsiveness and TH1 Differentiation Cytokine. 39: 20. DOI: 10.1016/J.CYTO.2007.07.075  0.426
2005 Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, Kano S, Honda K, Ohba Y, Mak TW, Taniguchi T. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature. 434: 243-9. PMID 15665823 DOI: 10.1038/nature03308  0.514
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