Daniel D. Oprian, Ph.D. - Publications

Affiliations: 
Biochemistry Brandeis University, Waltham, MA, United States 
Area:
GPCR membrane protein crystallography

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Morehouse BR, Kumar RP, Matos JO, Yu Q, Bannister A, Malik K, Temme JS, Krauss IJ, Oprian DD. Direct evidence for an enzyme generated LPP intermediate in (+)-limonene synthase using a fluorinated GPP substrate analog. Acs Chemical Biology. PMID 31433159 DOI: 10.1021/acschembio.9b00514  0.84
2019 Ozdeslik RN, Olinski LE, Trieu MM, Oprian DD, Oancea E. Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097585 DOI: 10.1073/pnas.1902825116  0.84
2017 Kumar RP, Morehouse BR, Fofana J, Trieu MM, Zhou DH, Lorenz MO, Oprian DD. Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC. The Journal of Biological Chemistry. PMID 29118188 DOI: 10.1074/jbc.M117.812685  0.84
2017 Lamarche LB, Kumar RP, Trieu MM, Devine EL, Theobald DL, Oprian DD. Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetics Tool from the Choanoflagellate Salpingoeca rosetta. Biochemistry. PMID 28976747 DOI: 10.1021/acs.biochem.7b00519  1
2017 Trieu MM, Devine EL, Lamarche LB, Ammerman AE, Greco JA, Birge RR, Theobald DL, Oprian DD. Expression, Purification, and Spectral Tuning of RhoGC, a Retinylidene/Guanylyl Cyclase Fusion Protein and Optogenetics Tool from the Aquatic Fungus Blastocladiella emersonii. The Journal of Biological Chemistry. PMID 28473465 DOI: 10.1074/jbc.M117.789636  1
2017 Kumar RP, Morehouse BR, Matos JO, Malik K, Lin H, Krauss IJ, Oprian DD. Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis using Fluorinated Substrate Analogs. Biochemistry. PMID 28272876 DOI: 10.1021/acs.biochem.7b00144  0.84
2017 Morehouse BR, Kumar RP, Matos JO, Olsen SN, Entova S, Oprian DD. Functional and Structural Characterization of a (+)-Limonene Synthase from Citrus sinensis. Biochemistry. PMID 28272875 DOI: 10.1021/acs.biochem.7b00143  0.84
2016 Devine EL, Theobald DL, Oprian DD. Relocating the active-site lysine in rhodopsin: 2. Evolutionary intermediates. Biochemistry. PMID 27486845 DOI: 10.1021/acs.biochem.6b00478  1
2015 Chakrabarti KS, Agafonov RV, Pontiggia F, Otten R, Higgins MK, Schertler GF, Oprian DD, Kern D. Conformational Selection in a Protein-Protein Interaction Revealed by Dynamic Pathway Analysis. Cell Reports. PMID 26725117 DOI: 10.1016/j.celrep.2015.12.010  1
2015 Kumar RP, Ranaghan MJ, Ganjei AY, Oprian DD. Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF-Hands. Biochemistry. PMID 26584024 DOI: 10.1021/acs.biochem.5b01160  1
2014 D'Antona AM, Xie G, Sligar SG, Oprian DD. Assembly of an activated rhodopsin-transducin complex in nanoscale lipid bilayers. Biochemistry. 53: 127-34. PMID 24328127 DOI: 10.1021/bi4012995  1
2014 Frederiksen R, Boyer NP, Nickle B, Chakrabarti KS, Koutalos Y, Crouch RK, Oprian D, Cornwall MC. Correction to Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods [The Journal of General Physiology, 139,6 (2012), 493-505] Journal of General Physiology. 144: 487. DOI: 10.1085/jgp.20111068510152014c  1
2013 Ranaghan MJ, Kumar RP, Chakrabarti KS, Buosi V, Kern D, Oprian DD. A highly conserved cysteine of neuronal calcium-sensing proteins controls cooperative binding of Ca2+ to recoverin. The Journal of Biological Chemistry. 288: 36160-7. PMID 24189072 DOI: 10.1074/jbc.M113.524355  1
2013 Devine EL, Oprian DD, Theobald DL. Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 13351-5. PMID 23904486 DOI: 10.1073/pnas.1306826110  1
2012 Frederiksen R, Boyer NP, Nickle B, Chakrabarti KS, Koutalos Y, Crouch RK, Oprian D, Cornwall MC. Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods. The Journal of General Physiology. 139: 493-505. PMID 22641642 DOI: 10.1085/jgp.201110685  1
2012 Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J. Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proceedings of the National Academy of Sciences of the United States of America. 109: 119-24. PMID 22198838 DOI: 10.1073/pnas.1114089108  1
2011 Xie G, D'Antona AM, Edwards PC, Fransen M, Standfuss J, Schertler GF, Oprian DD. Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin. Biochemistry. 50: 10399-407. PMID 21995315 DOI: 10.1021/bi201126r  1
2011 Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, Schertler GF. The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature. 471: 656-60. PMID 21389983 DOI: 10.1038/nature09795  1
2007 Standfuss J, Xie G, Edwards PC, Burghammer M, Oprian DD, Schertler GF. Crystal structure of a thermally stable rhodopsin mutant. Journal of Molecular Biology. 372: 1179-88. PMID 17825322 DOI: 10.1016/j.jmb.2007.03.007  1
2007 Bayburt TH, Leitz AJ, Xie G, Oprian DD, Sligar SG. Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. The Journal of Biological Chemistry. 282: 14875-81. PMID 17395586 DOI: 10.1074/jbc.M701433200  1
2006 Chen J, Shi G, Concepcion FA, Xie G, Oprian D. Stable rhodopsin/arrestin complex leads to retinal degeneration in a transgenic mouse model of autosomal dominant retinitis pigmentosa Journal of Neuroscience. 26: 11929-11937. PMID 17108167 DOI: 10.1523/JNEUROSCI.3212-06.2006  1
2006 Higgins MK, Oprian DD, Schertler GF. Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase, inhibiting rhodopsin phosphorylation without affecting catalytic activity of the kinase. The Journal of Biological Chemistry. 281: 19426-32. PMID 16675451 DOI: 10.1074/jbc.M602203200  1
2006 Tam BM, Xie G, Oprian DD, Moritz OL. Mislocalized rhodopsin does not require activation to cause retinal degeneration and neurite outgrowth in Xenopus laevis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 203-9. PMID 16399688 DOI: 10.1523/JNEUROSCI.3849-05.2006  1
2005 Kono M, Crouch RK, Oprian DD. A dark and constitutively active mutant of the tiger salamander UV pigment. Biochemistry. 44: 799-804. PMID 15641808 DOI: 10.1021/bi047898f  1
2004 Kim JM, Altenbach C, Kono M, Oprian DD, Hubbell WL, Khorana HG. Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. Proceedings of the National Academy of Sciences of the United States of America. 101: 12508-13. PMID 15306683 DOI: 10.1073/pnas.0404519101  1
2004 Das J, Crouch RK, Ma JX, Oprian DD, Kono M. Role of the 9-methyl group of retinal in cone visual pigments. Biochemistry. 43: 5532-8. PMID 15122919 DOI: 10.1021/bi036097u  1
2003 Jin S, Cornwall MC, Oprian DD. Opsin activation as a cause of congenital night blindness. Nature Neuroscience. 6: 731-5. PMID 12778053 DOI: 10.1038/nn1070  1
2003 Jin S, McKee TD, Oprian DD. An improved rhodopsin/EGFP fusion protein for use in the generation of transgenic Xenopus laevis. Febs Letters. 542: 142-6. PMID 12729914 DOI: 10.1016/S0014-5793(03)00368-5  1
2003 Oprian DD. Phototaxis, chemotaxis and the missing link. Trends in Biochemical Sciences. 28: 167-9. PMID 12713898 DOI: 10.1016/S0968-0004(03)00056-2  1
2003 Gross AK, Rao VR, Oprian DD. Characterization of rhodopsin congenital night blindness mutant T94I. Biochemistry. 42: 2009-15. PMID 12590588 DOI: 10.1021/bi020613j  1
2003 Gross AK, Xie G, Oprian DD. Slow binding of retinal to rhodopsin mutants G90D and T94D. Biochemistry. 42: 2002-8. PMID 12590587 DOI: 10.1021/bi020612r  1
2003 Xie G, Gross AK, Oprian DD. An opsin mutant with increased thermal stability. Biochemistry. 42: 1995-2001. PMID 12590586 DOI: 10.1021/bi020611z  1
2002 Fasick JI, Applebury ML, Oprian DD. Spectral tuning in the mammalian short-wavelength sensitive cone pigments. Biochemistry. 41: 6860-5. PMID 12022891 DOI: 10.1021/bi0200413  1
2002 Abdulaev NG, Strassmaier TT, Ngo T, Chen R, Luecke H, Oprian DD, Ridge KD. Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity. Structure (London, England : 1993). 10: 515-25. PMID 11937056 DOI: 10.1016/S0969-2126(02)00752-9  1
2001 Ma J, Znoiko S, Othersen KL, Ryan JC, Das J, Isayama T, Kono M, Oprian DD, Corson DW, Cornwall MC, Cameron DA, Harosi FI, Makino CL, Crouch RK. A visual pigment expressed in both rod and cone photoreceptors. Neuron. 32: 451-61. PMID 11709156 DOI: 10.1016/S0896-6273(01)00482-2  1
2001 Ma JX, Kono M, Xu L, Das J, Ryan JC, Hazard ES, Oprian DD, Crouch RK. Salamander UV cone pigment: sequence, expression, and spectral properties. Visual Neuroscience. 18: 393-9. PMID 11497415 DOI: 10.1017/S0952523801183057  1
2000 Zhou G, Ferrer M, Chopra R, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Harrison SC, Wiley DC. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorganic & Medicinal Chemistry. 8: 2219-27. PMID 11026535 DOI: 10.1016/S0968-0896(00)00155-3  1
2000 Struthers M, Yu H, Oprian DD. G protein-coupled receptor activation: analysis of a highly constrained, "straitjacketed" rhodopsin. Biochemistry. 39: 7938-42. PMID 10891074 DOI: 10.1021/bi000771f  1
2000 Struthers M, Oprian DD. Mapping tertiary contacts between amino acid residues within rhodopsin. Methods in Enzymology. 315: 130-43. PMID 10736699  1
1999 Fasick JI, Lee N, Oprian DD. Spectral tuning in the human blue cone pigment. Biochemistry. 38: 11593-6. PMID 10512613 DOI: 10.1021/bi991600h  1
1999 Yu H, Oprian DD. Tertiary interactions between transmembrane segments 3 and 5 near the cytoplasmic side of rhodopsin. Biochemistry. 38: 12033-40. PMID 10508407 DOI: 10.1021/bi9909492  1
1999 Yu H, Kono M, Oprian DD. State-dependent disulfide cross-linking in rhodopsin. Biochemistry. 38: 12028-32. PMID 10508406 DOI: 10.1021/bi990948+  1
1999 Ferrer M, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Wiley DC, Harrison SC. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nature Structural Biology. 6: 953-60. PMID 10504731 DOI: 10.1038/13324  1
1999 Struthers M, Yu H, Kono M, Oprian DD. Tertiary interactions between the fifth and sixth transmembrane segments of rhodopsin. Biochemistry. 38: 6597-603. PMID 10350478 DOI: 10.1021/bi9902384  1
1998 Kono M, Yu H, Oprian DD. Disulfide bond exchange in rhodopsin. Biochemistry. 37: 1302-5. PMID 9477956 DOI: 10.1021/bi9721445  1
1997 Yang T, Snider BB, Oprian DD. Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 94: 13559-64. PMID 9391065 DOI: 10.1073/pnas.94.25.13559  1
1997 Rim J, Faurobert E, Hurley JB, Oprian DD. In vitro assay for trans-phosphorylation of rhodopsin by rhodopsin kinase. Biochemistry. 36: 7064-70. PMID 9188705 DOI: 10.1021/bi970470e  1
1997 Kochendoerfer GG, Wang Z, Oprian DD, Mathies RA. Resonance Raman examination of the wavelength regulation mechanism in human visual pigments. Biochemistry. 36: 6577-87. PMID 9184137 DOI: 10.1021/bi970322o  1
1996 Rao VR, Oprian DD. Activating mutations of rhodopsin and other G protein-coupled receptors. Annual Review of Biophysics and Biomolecular Structure. 25: 287-314. PMID 8800472 DOI: 10.1146/annurev.bb.25.060196.001443  1
1995 Yu H, Kono M, McKee TD, Oprian DD. A general method for mapping tertiary contacts between amino acid residues in membrane-embedded proteins. Biochemistry. 34: 14963-9. PMID 7578109  1
1995 Rim J, Oprian DD. Constitutive activation of opsin: interaction of mutants with rhodopsin kinase and arrestin. Biochemistry. 34: 11938-45. PMID 7547930 DOI: 10.1021/bi00037a035  1
1995 Oprian DD. Structure of the cGMP-gated channel Behavioral and Brain Sciences. 18: 482-483.  1
1994 Asenjo AB, Rim J, Oprian DD. Molecular determinants of human red/green color discrimination. Neuron. 12: 1131-8. PMID 8185948 DOI: 10.1016/0896-6273(94)90320-4  1
1994 Govardhan CP, Oprian DD. Active site-directed inactivation of constitutively active mutants of rhodopsin. The Journal of Biological Chemistry. 269: 6524-7. PMID 8120004  1
1994 Rao VR, Cohen GB, Oprian DD. Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness. Nature. 367: 639-42. PMID 8107847 DOI: 10.1038/367639a0  1
1993 Wang Z, Asenjo AB, Oprian DD. Identification of the Cl(-)-binding site in the human red and green color vision pigments. Biochemistry. 32: 2125-30. PMID 8443153  1
1993 Dryja TP, Berson EL, Rao VR, Oprian DD. Heterozygous missense mutation in the rhodopsin gene as a cause of congenital stationary night blindness. Nature Genetics. 4: 280-3. PMID 8358437 DOI: 10.1038/ng0793-280  1
1993 Cohen GB, Yang T, Robinson PR, Oprian DD. Constitutive activation of opsin: influence of charge at position 134 and size at position 296. Biochemistry. 32: 6111-5. PMID 8099498  1
1992 Oprian DD. Molecular determinants of spectral properties and signal transduction in the visual pigments. Current Opinion in Neurobiology. 2: 428-32. PMID 1525538 DOI: 10.1016/0959-4388(92)90175-K  1
1992 Cohen GB, Oprian DD, Robinson PR. Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296. Biochemistry. 31: 12592-601. PMID 1472495  1
1992 Robinson PR, Cohen GB, Zhukovsky EA, Oprian DD. Constitutively active mutants of rhodopsin. Neuron. 9: 719-25. PMID 1356370 DOI: 10.1016/0896-6273(92)90034-B  1
1992 Zhukovsky EA, Robinson PR, Oprian DD. Changing the location of the Schiff base counterion in rhodopsin. Biochemistry. 31: 10400-5. PMID 1329948  1
1992 Oprian DD. The ligand-binding domain of rhodopsin and other G protein-linked receptors. Journal of Bioenergetics and Biomembranes. 24: 211-7. PMID 1326517 DOI: 10.1007/BF00762679  1
1991 Zhukovsky EA, Robinson PR, Oprian DD. Transducin activation by rhodopsin without a covalent bond to the 11-cis-retinal chromophore. Science (New York, N.Y.). 251: 558-60. PMID 1990431  1
1991 Oprian DD, Asenjo AB, Lee N, Pelletier SL. Design, chemical synthesis, and expression of genes for the three human color vision pigments. Biochemistry. 30: 11367-72. PMID 1742276  1
1989 Zhukovsky EA, Oprian DD. Effect of carboxylic acid side chains on the absorption maximum of visual pigments. Science (New York, N.Y.). 246: 928-30. PMID 2573154  1
1988 Franke RR, Sakmar TP, Oprian DD, Khorana HG. A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. The Journal of Biological Chemistry. 263: 2119-22. PMID 3123487  1
1988 Braiman M, Bubis J, Doi T, Chen HB, Flitsch SL, Franke RR, Gilles-Gonzalez MA, Graham RM, Karnik SS, Khorana HG. Studies on light transduction by bacteriorhodopsin and rhodopsin. Cold Spring Harbor Symposia On Quantitative Biology. 53: 355-64. PMID 3076084  1
1987 Oprian DD, Molday RS, Kaufman RJ, Khorana HG. Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 8874-8. PMID 2962193  1
1986 Ferretti L, Karnik SS, Khorana HG, Nassal M, Oprian DD. Total synthesis of a gene for bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 83: 599-603. PMID 3456156 DOI: 10.1007/s12045-012-0134-4  1
1985 Yatsunami K, Pandya BV, Oprian DD, Khorana HG. cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. Proceedings of the National Academy of Sciences of the United States of America. 82: 1936-40. PMID 2984674  1
1985 Barrett DJ, Redmond TM, Wiggert B, Oprian DD, Chader GJ, Nickerson JM. cDNA clones encoding bovine interphotoreceptor retinoid binding protein. Biochemical and Biophysical Research Communications. 131: 1086-93. PMID 2413855 DOI: 10.1016/0006-291X(85)90202-5  1
1984 Yatsunami K, Pandya BV, Oprian DD, Khorana G. The cloning of the genes for the GTPase and cyclic GMP phosphodiesterase of rod outer segments Federation Proceedings. 43: no. 1800.  1
1983 Oprian DD, Gorsky LD, Coon MJ. Properties of the oxygenated form of liver microsomal cytochrome P-450. The Journal of Biological Chemistry. 258: 8684-91. PMID 6863307  1
1982 Oprian DD, Coon MJ. Oxidation-reduction states of FMN and FAD in NADPH-cytochrome P-450 reductase during reduction by NADPH. The Journal of Biological Chemistry. 257: 8935-44. PMID 6807985  1
1979 Oprian DD, Vatsis KP, Coon MJ. Kinetics of reduction of cytochrome P-450LM4 in a reconstituted liver microsomal enzyme system. The Journal of Biological Chemistry. 254: 8895-902. PMID 113404  1
1979 Vatsis KP, Oprian DD, Coon MJ. Kinetics of reduction of purified liver microsomal cytochrome P-450 in the reconstituted enzyme system studied by stopped flow spectrophotometry. Acta Biologica Et Medica Germanica. 38: 459-73. PMID 42251  1
1979 Coon MJ, Blake RC, Oprian DD, Ballou DP. Mechanistic studies with purified components of the liver microsomal hydroxylation system: spectral intermediates in reaction of cytochrome P-450 with peroxy compounds. Acta Biologica Et Medica Germanica. 38: 449-58. PMID 42250  1
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