Walker S Jackson, Ph.D. - Publications

Affiliations: 
German Center for Neurodegenerative Diseases, Bonn 
Area:
prion diseases, FFI, CJD, transgenic mice

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mehra S, Bourkas ME, Kaczmarczyk L, Stuart E, Arshad H, Griffin JK, Frost KL, Walsh DJ, Supattapone S, Booth SA, Jackson WS, Watts JC. Convergent generation of atypical prions in knockin mouse models of genetic prion disease. The Journal of Clinical Investigation. 134. PMID 39087478 DOI: 10.1172/JCI176344  0.557
2024 Arifin MI, Hannaoui S, Ng RA, Zeng D, Zemlyankina I, Ahmed-Hassan H, Schatzl HM, Kaczmarczyk L, Jackson WS, Benestad SL, Gilch S. Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein. Plos Pathogens. 20: e1012350. PMID 38950080 DOI: 10.1371/journal.ppat.1012350  0.526
2024 Walsh DJ, Rees JR, Mehra S, Bourkas MEC, Kaczmarczyk L, Stuart E, Jackson WS, Watts JC, Supattapone S. Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease. Plos Pathogens. 20: e1012087. PMID 38557815 DOI: 10.1371/journal.ppat.1012087  0.451
2024 Jackson WS, Bauer S, Kaczmarczyk L, Magadi SS. Selective Vulnerability to Neurodegenerative Disease: Insights from Cell Type-Specific Translatome Studies. Biology. 13. PMID 38392286 DOI: 10.3390/biology13020067  0.456
2023 Walsh DJ, Rees JR, Mehra S, Bourkas MEC, Kaczmarczyk L, Stuart E, Jackson WS, Watts JC, Supattapone S. Anti-prion drugs do not improve survival in knock-in models of inherited prion disease. Biorxiv : the Preprint Server For Biology. PMID 37808761 DOI: 10.1101/2023.09.28.559951  0.486
2023 Jackson WS. Etiology matters: genetic and acquired prion diseases engage different mechanisms at a presymptomatic stage. Neural Regeneration Research. 18: 2707-2708. PMID 37449633 DOI: 10.4103/1673-5374.373684  0.321
2023 Arifin MI, Kaczmarczyk L, Zeng D, Hannaoui S, Lee C, Chang SC, Mitchell G, McKenzie D, Beekes M, Jackson W, Gilch S. Heterozygosity for cervid S138N polymorphism results in subclinical CWD in gene-targeted mice and progressive inhibition of prion conversion. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221060120. PMID 37014866 DOI: 10.1073/pnas.2221060120  0.514
2023 Bauer S, Chen CY, Jonson M, Kaczmarczyk L, Magadi SS, Jackson WS. Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington's disease mice. Acta Neuropathologica Communications. 11: 17. PMID 36670467 DOI: 10.1186/s40478-022-01500-x  0.382
2023 Vallabh SM, Zou D, Pitstick R, O'Moore J, Peters J, Silvius D, Kriz J, Jackson WS, Carlson GA, Minikel EV, Cabin DE. Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease. Journal of Virology. e0167222. PMID 36651748 DOI: 10.1128/jvi.01672-22  0.46
2022 Bauer S, Dittrich L, Kaczmarczyk L, Schleif M, Benfeitas R, Jackson WS. Translatome profiling in fatal familial insomnia implicates TOR signaling in somatostatin neurons. Life Science Alliance. 5. PMID 36192034 DOI: 10.26508/lsa.202201530  0.446
2022 Kaczmarczyk L, Schleif M, Dittrich L, Williams RH, Koderman M, Bansal V, Rajput A, Schulte T, Jonson M, Krost C, Testaquadra FJ, Bonn S, Jackson WS. Distinct translatome changes in specific neural populations precede electroencephalographic changes in prion-infected mice. Plos Pathogens. 18: e1010747. PMID 35960762 DOI: 10.1371/journal.ppat.1010747  0.458
2022 Thackray AM, Lam B, McNulty EE, Nalls AV, Mathiason CK, Magadi SS, Jackson WS, Andréoletti O, Marrero-Winkens C, Schätzl H, Bujdoso R. Clearance of variant Creutzfeldt-Jakob disease prions in vivo by the Hsp70 disaggregase system. Brain : a Journal of Neurology. PMID 35446941 DOI: 10.1093/brain/awac144  0.442
2021 Kaczmarczyk L, Reichenbach N, Blank N, Jonson M, Dittrich L, Petzold GC, Jackson WS. Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background. Scientific Reports. 11: 5412. PMID 33686166 DOI: 10.1038/s41598-021-84887-2  0.352
2020 Poll S, Mittag M, Musacchio F, Justus LC, Giovannetti EA, Steffen J, Wagner J, Zohren L, Schoch S, Schmidt B, Jackson WS, Ehninger D, Fuhrmann M. Memory trace interference impairs recall in a mouse model of Alzheimer's disease. Nature Neuroscience. PMID 32514139 DOI: 10.1038/S41593-020-0652-4  0.301
2019 Kaczmarczyk L, Bansal V, Rajput A, Rahman RU, Krzyżak W, Degen J, Poll S, Fuhrmann M, Bonn S, Jackson WS. Tagger-A Swiss army knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice. Plos Biology. 17: e3000374. PMID 31393866 DOI: 10.1371/Journal.Pbio.3000374  0.335
2018 Rakers C, Schleif M, Blank N, Matušková H, Ulas T, Händler K, Torres SV, Schumacher T, Tai K, Schultze JL, Jackson WS, Petzold GC. Stroke target identification guided by astrocyte transcriptome analysis. Glia. PMID 30585358 DOI: 10.1002/Glia.23544  0.373
2018 Linsenmeier L, Mohammadi B, Wetzel S, Puig B, Jackson WS, Hartmann A, Uchiyama K, Sakaguchi S, Endres K, Tatzelt J, Saftig P, Glatzel M, Altmeppen HC. Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein. Molecular Neurodegeneration. 13: 18. PMID 29625583 DOI: 10.1186/S13024-018-0248-6  0.464
2018 Xie K, Ryan DP, Pearson BL, Henzel KS, Neff F, Vidal RO, Hennion M, Lehmann I, Schleif M, Schröder S, Adler T, Rathkolb B, Rozman J, Schütz AL, Prehn C, ... ... Jackson WS, et al. Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29467291 DOI: 10.1073/Pnas.1707337115  0.387
2017 Thackray AM, Cardova A, Wolf H, Pradl L, Vorberg I, Jackson WS, Bujdoso R. Genetic human prion disease modelled in PrP transgenic Drosophila. The Biochemical Journal. PMID 28814578 DOI: 10.1042/Bcj20170462  0.579
2017 Dittrich L, Petese A, Jackson WS. The natural Disc1-deletion present in several inbred mouse strains does not affect sleep. Scientific Reports. 7: 5665. PMID 28720848 DOI: 10.1016/J.Sleep.2017.11.228  0.326
2016 Kaczmarczyk L, Mende Y, Zevnik B, Jackson WS. Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9. Plos One. 11: e0154604. PMID 27128441 DOI: 10.1371/Journal.Pone.0154604  0.528
2015 Jackson WS, Kaczmarczyk L. Astonishing advances in mouse genetic tools for biomedical research. Swiss Medical Weekly. 145: w14186. PMID 26513700 DOI: 10.4414/Smw.2015.14186  0.369
2015 Bujdoso R, Landgraf M, Jackson WS, Thackray AM. Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response. World Journal of Virology. 4: 188-97. PMID 26279981 DOI: 10.5501/Wjv.V4.I3.188  0.596
2015 Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S. Requirements for mutant and wild-type prion protein misfolding in vitro. Biochemistry. 54: 1180-7. PMID 25584902 DOI: 10.1021/bi501495j  0.388
2014 Jackson WS, Krost C. Peculiarities of prion diseases. Plos Pathogens. 10: e1004451. PMID 25411777 DOI: 10.1371/Journal.Ppat.1004451  0.57
2014 Jackson WS, Krost C, Borkowski AW, Kaczmarczyk L. Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain. Plos One. 9: e95958. PMID 24752288 DOI: 10.1371/Journal.Pone.0095958  0.513
2014 Jackson WS. Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein. Disease Models & Mechanisms. 7: 21-9. PMID 24396151 DOI: 10.1242/Dmm.012146  0.548
2013 Jackson WS, Borkowski AW, Watson NE, King OD, Faas H, Jasanoff A, Lindquist S. Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases. Proceedings of the National Academy of Sciences of the United States of America. 110: 14759-64. PMID 23959875 DOI: 10.1073/Pnas.1312006110  0.716
2010 Faas H, Jackson WS, Borkowski AW, Wang X, Ma J, Lindquist S, Jasanoff A. Context-dependent perturbation of neural systems in transgenic mice expressing a cytosolic prion protein. Neuroimage. 49: 2607-17. PMID 19835963 DOI: 10.1016/J.Neuroimage.2009.10.009  0.602
2009 Steele AD, Zhou Z, Jackson WS, Zhu C, Auluck P, Moskowitz MA, Chesselet MF, Lindquist S. Context dependent neuroprotective properties of prion protein (PrP). Prion. 3: 240-9. PMID 19901559 DOI: 10.4161/Pri.3.4.10135  0.708
2009 Jackson WS, Borkowski AW, Faas H, Steele AD, King OD, Watson N, Jasanoff A, Lindquist S. Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice. Neuron. 63: 438-50. PMID 19709627 DOI: 10.1016/J.Neuron.2009.07.026  0.701
2008 Heikenwalder M, Kurrer MO, Margalith I, Kranich J, Zeller N, Haybaeck J, Polymenidou M, Matter M, Bremer J, Jackson WS, Lindquist S, Sigurdson CJ, Aguzzi A. Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. Immunity. 29: 998-1008. PMID 19100703 DOI: 10.1016/J.Immuni.2008.10.014  0.599
2008 Steele AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King OD, Raymond GJ, Aguzzi A, Lindquist S. Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 13626-31. PMID 18757733 DOI: 10.1073/Pnas.0806319105  0.722
2007 Steele AD, Hetz C, Yi CH, Jackson WS, Borkowski AW, Yuan J, Wollmann RH, Lindquist S. Prion pathogenesis is independent of caspase-12. Prion. 1: 243-7. PMID 19164919 DOI: 10.4161/Pri.1.4.5551  0.704
2007 Jackson WS, Lindquist S. Illuminating aggregate heterogeneity in neurodegenerative disease. Nature Methods. 4: 1000-1. PMID 18049468 DOI: 10.1038/Nmeth1207-1000  0.54
2007 Steele AD, King OD, Jackson WS, Hetz CA, Borkowski AW, Thielen P, Wollmann R, Lindquist S. Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13022-7. PMID 18032675 DOI: 10.1523/Jneurosci.3290-07.2007  0.712
2007 Steele AD, Jackson WS, King OD, Lindquist S. The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proceedings of the National Academy of Sciences of the United States of America. 104: 1983-8. PMID 17261803 DOI: 10.1073/Pnas.0610779104  0.682
2003 Jackson WS, Tallaksen-Greene SJ, Albin RL, Detloff PJ. Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context. Human Molecular Genetics. 12: 1621-9. PMID 12812988 DOI: 10.1093/Hmg/Ddg163  0.321
2001 Lin CH, Tallaksen-Greene S, Chien WM, Cearley JA, Jackson WS, Crouse AB, Ren S, Li XJ, Albin RL, Detloff PJ. Neurological abnormalities in a knock-in mouse model of Huntington's disease. Human Molecular Genetics. 10: 137-44. PMID 11152661 DOI: 10.1093/Hmg/10.2.137  0.428
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