Year |
Citation |
Score |
2023 |
Pal R, Hui D, Menchen H, Zhao H, Mozziconacci O, Wilkins H, Blagg BSJ, Schöneich C, Swerdlow RH, Michaelis ML, Michaelis EK. Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target. Frontiers in Aging Neuroscience. 15: 1282855. PMID 38035268 DOI: 10.3389/fnagi.2023.1282855 |
0.717 |
|
2019 |
Agbas A, Krishnamurthy P, Michaelis ML, Michaelis EK. Mitochondrial Electron Transfer Cascade Enzyme Activity Assessment in Cultured Neurons and Select Brain Regions. Current Protocols in Toxicology. e73. PMID 30951613 DOI: 10.1002/Cptx.73 |
0.357 |
|
2016 |
Wilkins HM, Koppel S, Carl SM, Ramanujan S, Weidling I, Michaelis ML, Michaelis EK, Swerdlow RH. Oxaloacetate Enhances Neuronal Cell Bioenergetic Fluxes and Infrastructure. Journal of Neurochemistry. PMID 26811028 DOI: 10.1111/Jnc.13545 |
0.314 |
|
2014 |
Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. Human Molecular Genetics. 23: 6528-41. PMID 25027327 DOI: 10.1093/Hmg/Ddu371 |
0.355 |
|
2014 |
Jiang L, Bechtel MD, Bean JL, Winefield R, Williams TD, Zaidi A, Michaelis EK, Michaelis ML. Effects of gangliosides on the activity of the plasma membrane Ca2+-ATPase. Biochimica Et Biophysica Acta. 1838: 1255-65. PMID 24434060 DOI: 10.1016/J.Bbamem.2014.01.003 |
0.395 |
|
2012 |
Jiang L, Bechtel MD, Galeva NA, Williams TD, Michaelis EK, Michaelis ML. Decreases in plasma membrane Ca²âº-ATPase in brain synaptic membrane rafts from aged rats. Journal of Neurochemistry. 123: 689-99. PMID 22889001 DOI: 10.1111/J.1471-4159.2012.07918.X |
0.351 |
|
2012 |
Zhao H, Michaelis ML, Blagg BS. Hsp90 modulation for the treatment of Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 1-25. PMID 22840743 DOI: 10.1016/B978-0-12-394816-8.00001-5 |
0.321 |
|
2011 |
Hascup KN, Bao X, Hascup ER, Hui D, Xu W, Pomerleau F, Huettl P, Michaelis ML, Michaelis EK, Gerhardt GA. Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum. Asn Neuro. 3. PMID 21446915 DOI: 10.1042/An20110005 |
0.341 |
|
2011 |
Kim J, Choi IY, Michaelis ML, Lee P. Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI. Neuroimage. 56: 1286-92. PMID 21338698 DOI: 10.1016/J.Neuroimage.2011.02.039 |
0.308 |
|
2010 |
Wang X, Michaelis ML, Michaelis EK. Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Current Genomics. 11: 618-33. PMID 21629439 DOI: 10.2174/138920210793360943 |
0.379 |
|
2010 |
Jiang L, Fang J, Moore DS, Gogichaeva NV, Galeva NA, Michaelis ML, Zaidi A. Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis. Neurobiology of Aging. 31: 2146-59. PMID 19118924 DOI: 10.1016/J.Neurobiolaging.2008.11.005 |
0.337 |
|
2009 |
Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK. Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13929-44. PMID 19890003 DOI: 10.1523/Jneurosci.4413-09.2009 |
0.418 |
|
2009 |
Desino KE, Ansar S, Georg GI, Himes RH, Michaelis ML, Powell DR, Reiff EA, Telikepalli H, Audus KL. (3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent. Journal of Medicinal Chemistry. 52: 7537-43. PMID 19728715 DOI: 10.1021/Jm900254K |
0.304 |
|
2009 |
Zaidi A, Fernandes D, Bean JL, Michaelis ML. Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca(2+)-ATPase. Free Radical Biology & Medicine. 47: 1507-14. PMID 19715754 DOI: 10.1016/J.Freeradbiomed.2009.08.018 |
0.433 |
|
2009 |
Desino KE, Pignatello R, Guccione S, Basile L, Ansar S, Michaelis ML, Ramsay RR, Audus KL. TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability. Biochemical Pharmacology. 78: 1412-7. PMID 19679106 DOI: 10.1016/J.Bcp.2009.07.027 |
0.305 |
|
2009 |
Wang X, Zaidi A, Pal R, Garrett AS, Braceras R, Chen XW, Michaelis ML, Michaelis EK. Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. Bmc Neuroscience. 10: 12. PMID 19228403 DOI: 10.1186/1471-2202-10-12 |
0.427 |
|
2009 |
Lu Y, Ansar S, Michaelis ML, Blagg BS. Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line. Bioorganic & Medicinal Chemistry. 17: 1709-15. PMID 19138859 DOI: 10.1016/J.Bmc.2008.12.047 |
0.498 |
|
2009 |
Michaelis ML, Georg G, Telikepalli H, McIntosh M, Rajewski RA. Ongoing in vivo studies with cytoskeletal drugs in tau transgenic mice (Current Alzheimer Research 3, 3, (215-219)) Current Alzheimer Research. 6: 320. DOI: 10.2174/156720509788486635 |
0.323 |
|
2008 |
Seyb KI, Schuman ER, Ni J, Huang MM, Michaelis ML, Glicksman MA. Identification of small molecule inhibitors of beta-amyloid cytotoxicity through a cell-based high-throughput screening platform. Journal of Biomolecular Screening. 13: 870-8. PMID 18812568 DOI: 10.1177/1087057108323909 |
0.737 |
|
2008 |
Michaelis EK, Bao X, Pal R, Hascup K, McKerchar T, Xu W, Hui D, Agbas A, Wang X, Pinkston J, Pomerleau F, Huettl P, Fowler S, Michaelis M, Gerhardt G. P4-259: Transgenic expression of glutamate gehydrogenase 1 in neurons: An in vivo model of hyperglutamatergic nervous system and chronic neurodegeneration Alzheimer's & Dementia. 4: T747-T747. DOI: 10.1016/J.Jalz.2008.05.2328 |
0.368 |
|
2008 |
Michaelis ML, Ansar S, Chigurupati R, Menchen H, Blagg B, Rajewski R. P2-384: In vivo
effects of novel Hsp90 C-terminal inhibitors in Tau mutant mice Alzheimer's & Dementia. 4: T485-T485. DOI: 10.1016/J.Jalz.2008.05.1462 |
0.674 |
|
2007 |
Jiang L, Fernandes D, Mehta N, Bean JL, Michaelis ML, Zaidi A. Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion. Journal of Neurochemistry. 102: 378-88. PMID 17596212 DOI: 10.1111/J.1471-4159.2007.04480.X |
0.372 |
|
2007 |
Fernandes D, Zaidi A, Bean J, Hui D, Michaelis ML. RNA--induced silencing of the plasma membrane Ca2+-ATPase 2 in neuronal cells: effects on Ca2+ homeostasis and cell viability. Journal of Neurochemistry. 102: 454-65. PMID 17488275 DOI: 10.1111/J.1471-4159.2007.04592.X |
0.388 |
|
2007 |
Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT. p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide. Journal of Molecular Neuroscience : Mn. 31: 23-35. PMID 17416967 DOI: 10.1007/Bf02686115 |
0.766 |
|
2007 |
Butler D, Bendiske J, Michaelis ML, Karanian DA, Bahr BA. Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. European Journal of Pharmacology. 562: 20-7. PMID 17336290 DOI: 10.1016/J.Ejphar.2007.01.053 |
0.373 |
|
2007 |
Ansar S, Burlison JA, Hadden MK, Yu XM, Desino KE, Bean J, Neckers L, Audus KL, Michaelis ML, Blagg BS. A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorganic & Medicinal Chemistry Letters. 17: 1984-90. PMID 17276679 DOI: 10.1016/J.Bmcl.2007.01.017 |
0.445 |
|
2006 |
Michaelis ML, Georg G, Telikepalli H, McIntosh M, Rajewski RA. Ongoing in vivo studies with cytoskeletal drugs in tau transgenic mice. Current Alzheimer Research. 3: 215-9. PMID 16842098 DOI: 10.2174/156720506777632880 |
0.393 |
|
2006 |
Seyb KI, Ansar S, Bean J, Michaelis ML. beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton. Journal of Molecular Neuroscience : Mn. 28: 111-23. PMID 16679552 DOI: 10.1385/Jmn:28:2:111 |
0.78 |
|
2006 |
Michaelis EK, Pal R, Schoneich C, Wilkins HM, Swerdlow RH, Michaelis ML. P1-225: PROTECTION AGAINST AB-INDUCED NEURONAL DAMAGE BY AN HSP90 C-TERMINAL MODULATOR: IMPORTANCE OF PYRUVATE DEHYDROGENASE KINASE Alzheimer's & Dementia. 14: P364-P365. DOI: 10.1016/J.Jalz.2018.06.230 |
0.423 |
|
2005 |
Lushington GH, Zaidi A, Michaelis ML. Theoretically predicted structures of plasma membrane Ca(2+)-ATPase and their susceptibilities to oxidation. Journal of Molecular Graphics & Modelling. 24: 175-85. PMID 16169758 DOI: 10.1016/J.Jmgm.2005.07.003 |
0.333 |
|
2005 |
Michaelis ML, Seyb KI, Ansar S. Cytoskeletal integrity as a drug target. Current Alzheimer Research. 2: 227-9. PMID 15974922 DOI: 10.2174/1567205053585837 |
0.766 |
|
2005 |
Rice A, Liu Y, Michaelis ML, Himes RH, Georg GI, Audus KL. Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ. Journal of Medicinal Chemistry. 48: 832-8. PMID 15689167 DOI: 10.1021/Jm040114B |
0.323 |
|
2005 |
Michaelis ML, Ansar S, Chen Y, Reiff ER, Seyb KI, Himes RH, Audus KL, Georg GI. {beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents. The Journal of Pharmacology and Experimental Therapeutics. 312: 659-68. PMID 15375176 DOI: 10.1124/Jpet.104.074450 |
0.785 |
|
2004 |
Michaelis ML, Seyb KI, Ansar S, Bean JL, Georg G. P3-192 Parallels between ER-stress and Aβ-induced toxicity in primary neurons: involvement of the cytoskeletal network Neurobiology of Aging. 25: S410. DOI: 10.1016/S0197-4580(04)81344-7 |
0.754 |
|
2003 |
Pal R, Agbas A, Bao X, Hui D, Leary C, Hunt J, Naniwadekar A, Michaelis ML, Kumar KN, Michaelis EK. Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins. Brain Research. 994: 1-18. PMID 14642443 DOI: 10.1016/J.Brainres.2003.08.046 |
0.314 |
|
2003 |
Rice A, Michaelis ML, Georg G, Liu Y, Turunen B, Audus KL. Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors. Journal of Molecular Neuroscience : Mn. 20: 339-43. PMID 14501017 DOI: 10.1385/Jmn:20:3:339 |
0.329 |
|
2003 |
Michaelis ML. Drugs targeting Alzheimer's disease: some things old and some things new. The Journal of Pharmacology and Experimental Therapeutics. 304: 897-904. PMID 12604663 DOI: 10.1124/Jpet.102.035840 |
0.409 |
|
2003 |
Li G, Faibushevich A, Turunen BJ, Yoon SO, Georg G, Michaelis ML, Dobrowsky RT. Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons. Journal of Neurochemistry. 84: 347-62. PMID 12558997 DOI: 10.1046/J.1471-4159.2003.01526.X |
0.487 |
|
2002 |
Michaelis ML, Dobrowsky RT, Li G. Tau neurofibrillary pathology and microtubule stability. Journal of Molecular Neuroscience : Mn. 19: 289-93. PMID 12540054 DOI: 10.1385/Jmn:19:3:289 |
0.483 |
|
2002 |
Michaelis ML, Chen Y, Hill S, Reiff E, Georg G, Rice A, Audus K. Amyloid peptide toxicity and microtubule-stabilizing drugs. Journal of Molecular Neuroscience : Mn. 19: 101-5. PMID 12212764 DOI: 10.1007/S12031-002-0018-2 |
0.532 |
|
2001 |
Zaidi A, Cross AM, Bean JL, Michaelis ML. Modification of Synaptic Plasma Membrane Ca2+-ATPase in Ischemic Injury in an Animal Model of Global Ischemia Stroke. 32: 354-354. DOI: 10.1161/01.Str.32.Suppl_1.354-A |
0.372 |
|
2000 |
Ranciat-McComb NS, Bland KS, Huschenbett J, Ramonda L, Bechtel M, Zaidi A, Michaelis ML. Antisense oligonucleotide suppression of Na(+)/Ca(2+) exchanger activity in primary neurons from rat brain. Neuroscience Letters. 294: 13-6. PMID 11044575 DOI: 10.1016/S0304-3940(00)01524-X |
0.363 |
|
1999 |
Zaidi A, Michaelis ML. Effects of reactive oxygen species on brain synaptic plasma membrane Ca2+-ATPase Free Radical Biology and Medicine. 27: 810-821. PMID 10515585 DOI: 10.1016/S0891-5849(99)00128-8 |
0.37 |
|
1998 |
Huschenbett J, Zaidi A, Michaelis ML. Sensitivity of the synaptic membrane Na+/Ca2+ exchanger and the expressed NCX1 isoform to reactive oxygen species Biochimica Et Biophysica Acta - Biomembranes. 1374: 34-46. PMID 9814850 DOI: 10.1016/S0005-2736(98)00121-7 |
0.34 |
|
1998 |
Michaelis ML, Ranciat N, Chen Y, Bechtel M, Ragan R, Hepperle M, Liu Y, Georg G. Protection against beta-amyloid toxicity in primary neurons by paclitaxel (Taxol). Journal of Neurochemistry. 70: 1623-7. PMID 9523579 DOI: 10.1046/J.1471-4159.1998.70041623.X |
0.579 |
|
1997 |
Chen X, Michaelis ML, Michaelis EK. Effects of chronic ethanol treatment on the expression of calcium transport carriers and NMDA/glutamate receptor proteins in brain synaptic membranes. Journal of Neurochemistry. 69: 1559-69. PMID 9326285 DOI: 10.1046/J.1471-4159.1997.69041559.X |
0.329 |
|
1996 |
Michaelis ML, Bigelow DJ, Schöneich C, Williams TD, Ramonda L, Yin D, Hühmer AFR, Yao Y, Gao J, Squier TC. Decreased plasma membrane calcium transport activity in aging brain Life Sciences. 59: 405-412. PMID 8761328 DOI: 10.1016/0024-3205(96)00319-0 |
0.307 |
|
1996 |
Michaelis EK, Chen X, Joseph DB, Hurlbert M, Kumar KN, Michaelis ML. Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex. Journal of Neurochemistry. 67: 201-11. PMID 8666993 DOI: 10.1046/J.1471-4159.1996.67010201.X |
0.321 |
|
1996 |
Bland KS, Takahashi K, Islam S, Michaelis ML. Effects of NCX1 antisense oligodeoxynucleotides on cardiac myocytes and primary neurons in culture. Annals of the New York Academy of Sciences. 779: 119-20. PMID 8659818 DOI: 10.1111/J.1749-6632.1996.Tb44777.X |
0.325 |
|
1996 |
Michaelis ML, Huschenbett J. Chapter 6 Neuronal Calcium Regulation in Aging Brain Advances in Cell Aging and Gerontology. 1: 139-155. DOI: 10.1016/S1566-3124(08)60041-3 |
0.366 |
|
1995 |
Xia Y, Ragan RE, Seah EE, Michaelis ML, Michaelis EK. Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochemical Research. 20: 617-29. PMID 7643968 DOI: 10.1007/Bf01694545 |
0.378 |
|
1994 |
Michaelis ML. Ion transport systems and Ca2+ regulation in aging neurons Annals of the New York Academy of Sciences. 747: 407-418. PMID 7847687 DOI: 10.1111/J.1749-6632.1994.Tb44425.X |
0.326 |
|
1994 |
Michaelis ML, Walsh JL, Pal R, Hurlbert M, Hoel G, Bland K, Foye J, Kwong WH. Immunologic localization and kinetic characterization of a Na+/Ca2+ exchanger in neuronal and non-neuronal cells Brain Research. 661: 104-116. PMID 7834362 DOI: 10.1016/0006-8993(94)91187-8 |
0.433 |
|
1992 |
Michaelis ML, Nunley EW, Jayawickreme C, Hurlbert M, Schueler S, Guilly C. Purification of a Synaptic Membrane Na+/Ca2+ Antiporter and Immunoextraction with Antibodies to a 36‐kDa Protein Journal of Neurochemistry. 58: 147-157. PMID 1727427 DOI: 10.1111/J.1471-4159.1992.Tb09290.X |
0.316 |
|
1992 |
Michaelis EK, Michaelis ML. Molecular aspects of glutamate receptors and sodium-calcium exchange carriers in mammalian brain: implications for neuronal development and degeneration. Neurochemical Research. 17: 29-34. PMID 1371600 DOI: 10.1007/Bf00966862 |
0.372 |
|
1990 |
Hoel G, Michaelis ML, Freed WJ, Kleinman JE. Characterization of Na(+)-Ca2+ exchange activity in plasma membrane vesicles from postmortem human brain. Neurochemical Research. 15: 881-7. PMID 1703282 DOI: 10.1007/Bf00965907 |
0.301 |
|
1989 |
MICHAELIS ML. Ca2+ Handling Systems and Neuronal Aging Annals of the New York Academy of Sciences. 568: 89-94. PMID 2629587 DOI: 10.1111/J.1749-6632.1989.Tb12494.X |
0.333 |
|
1987 |
Michaelis ML, Michaelis EK, Nunley EW, Galton N. Effects of chronic alcohol administration on synaptic membrane Na+-Ca2+ exchange activity. Brain Research. 414: 239-44. PMID 3620929 DOI: 10.1016/0006-8993(87)90004-7 |
0.324 |
|
1987 |
Michaelis E, Roy S, Galton N, Cunningham M, LeCluyse E, Michaelis M. Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats Neurochemistry International. 11: 209-218. DOI: 10.1016/0197-0186(87)90011-8 |
0.32 |
|
1985 |
Michaelis ML, Kitos TE, Tehan T. Differential effects of ethanol on two synaptic membrane Ca2+ transport systems Alcohol. 2: 129-132. PMID 4015827 DOI: 10.1016/0741-8329(85)90029-1 |
0.318 |
|
1984 |
Michaelis EK, Magruder CD, Lampe RA, Galton N, Chang HH, Michaelis ML. Effects of amphipathic drugs on L'[3H]glutamate binding to synaptic membranes and the purified binding protein. Neurochemical Research. 9: 29-44. PMID 6325975 DOI: 10.1007/Bf00967657 |
0.325 |
|
1984 |
Michaelis ML, Johe K, Kitos TE. Age-dependent alterations in synaptic membrane systems for Ca2+ regulation Mechanisms of Ageing and Development. 25: 215-225. PMID 6144821 DOI: 10.1016/0047-6374(84)90142-8 |
0.338 |
|
1983 |
Michaelis ML, Michaelis EK, Tehan T. Alcohol effects on synaptic membrane calcium ion fluxes. Pharmacology, Biochemistry, and Behavior. 18: 19-23. PMID 6314374 DOI: 10.1016/0091-3057(83)90141-7 |
0.311 |
|
1983 |
Michaelis ML, Michaelis EK. Alcohol and local anesthetic effects on Na+-dependent Ca2+ fluxes in brain synaptic membrane vesicles. Biochemical Pharmacology. 32: 963-9. PMID 6301510 DOI: 10.1016/0006-2952(83)90612-3 |
0.312 |
|
1983 |
Michaelis EK, Michaelis ML, Stormann TM, Chittenden WL, Grubbs RD. Purification and molecular characterization of the brain synaptic membrane glutamate-binding protein. Journal of Neurochemistry. 40: 1742-53. PMID 6133916 DOI: 10.1111/J.1471-4159.1983.Tb08150.X |
0.31 |
|
1981 |
Michaelis ML, Michaelis EK. Effects of 2-chloroadenosine on electric potentials in brain synaptic membrane vesicles. Biochimica Et Biophysica Acta. 648: 55-62. PMID 7295731 DOI: 10.1016/0005-2736(81)90123-1 |
0.306 |
|
1981 |
Michaelis EK, Michaelis ML, Chang HH, Grubbs RD, Kuonen DR. Molecular characteristics of glutamate receptors in the mammalian brain. Molecular and Cellular Biochemistry. 38: 163-79. PMID 6117005 DOI: 10.1007/978-94-009-8027-3_10 |
0.331 |
|
1980 |
Michaelis EK, Michaelis ML, Belieu RM, Grubbs RD, Magruder C. Effects of in vitro ethanol addition on brain synaptic membrane glutamate binding Brain Research Bulletin. 5: 647-651. DOI: 10.1016/0361-9230(80)90107-0 |
0.303 |
|
1976 |
Michaelis EK, Michaelis ML. Concanavalin A binding to brain particulate preparations and its effect on adenylate cyclase. Life Sciences. 18: 1021-8. PMID 1271959 DOI: 10.1016/0024-3205(76)90425-2 |
0.301 |
|
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