Year |
Citation |
Score |
2021 |
Caba E, Sherman MD, Farizatto KLG, Alcira B, Wang HW, Giardina C, Shin DG, Sandefur CI, Bahr BA. Excitotoxic stimulation activates distinct pathogenic and protective expression signatures in the hippocampus. Journal of Cellular and Molecular Medicine. PMID 34414662 DOI: 10.1111/jcmm.16864 |
0.767 |
|
2021 |
Almeida MF, Piehler T, Carstens KE, Zhao M, Samadi M, Dudek SM, Norton CJ, Parisian CM, Farizatto KLG, Bahr BA. Distinct and dementia-related synaptopathy in the hippocampus after military blast exposures. Brain Pathology (Zurich, Switzerland). e12936. PMID 33629462 DOI: 10.1111/bpa.12936 |
0.317 |
|
2020 |
Almeida MF, Bahr BA, Kinsey ST. Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease. International Review of Neurobiology. 154: 303-324. PMID 32739009 DOI: 10.1016/bs.irn.2020.02.012 |
0.331 |
|
2019 |
Lamani M, Malamas MS, Farah SI, Shukla VG, Almeida MF, Weerts CM, Anderson J, Wood JT, Farizatto KLG, Bahr BA, Makriyannis A. Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology. Bioorganic & Medicinal Chemistry. 115096. PMID 31629610 DOI: 10.1016/J.Bmc.2019.115096 |
0.42 |
|
2019 |
Hwang J, Estick CM, Ikonne US, Butler D, Pait MC, Elliott LH, Ruiz S, Smith K, Rentschler KM, Mundell C, Almeida MF, Bear NS, Locklear JP, Abumohsen Y, Ivey CM, ... ... Bahr BA, et al. The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment. International Journal of Molecular Sciences. 20. PMID 31505809 DOI: 10.3390/ijms20184432 |
0.397 |
|
2019 |
Farizatto KLG, Almeida MF, Long RT, Bahr BA. Early Synaptic Alterations and Selective Adhesion Signaling in Hippocampal Dendritic Zones Following Organophosphate Exposure. Scientific Reports. 9: 6532. PMID 31024077 DOI: 10.1038/s41598-019-42934-z |
0.436 |
|
2018 |
Piehler T, Zander N, Banton R, Smith M, Romine H, Benjamin R, Byrnes K, Duckworth J, Bahr BA. Effects on Neurons and Hippocampal Slices by Single and Multiple Primary Blast Pressure Waves From Detonating Spherical Cyclotrimethylenetrinitramine (RDX) Explosive Charges. Military Medicine. 183: 269-275. PMID 29635567 DOI: 10.1093/Milmed/Usx158 |
0.396 |
|
2018 |
Simões AP, Silva CG, Marques JM, Pochmann D, Porciúncula LO, Ferreira S, Oses JP, Beleza RO, Real JI, Köfalvi A, Bahr BA, Lerma J, Cunha RA, Rodrigues RJ. Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation. Cell Death & Disease. 9: 297. PMID 29463792 DOI: 10.1038/s41419-018-0351-1 |
0.488 |
|
2017 |
Romine H, Rentschler KM, Smith K, Edwards A, Colvin C, Farizatto K, Pait MC, Butler D, Bahr BA. Potential Alzheimer's Disease Therapeutics Among Weak Cysteine Protease Inhibitors Exhibit Mechanistic Differences Regarding Extent of Cathepsin B Up-Regulation and Ability to Block Calpain. European Scientific Journal. 13: 38-59. PMID 29805718 DOI: 10.19044/esj.2017.c1p5 |
0.367 |
|
2017 |
Farizatto KLG, Bahr BA. Paraoxon: An Anticholinesterase That Triggers an Excitotoxic Cascade of Oxidative Stress, Adhesion Responses, and Synaptic Compromise. European Scientific Journal. 13: 29-37. PMID 29805717 DOI: 10.19044/esj.2017.c1p4 |
0.405 |
|
2017 |
Wang C, Telpoukhovskaia MA, Bahr BA, Chen X, Gan L. Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases. Current Opinion in Neurobiology. 48: 52-58. PMID 29028540 DOI: 10.1016/j.conb.2017.09.005 |
0.312 |
|
2017 |
Farizatto KLG, McEwan SA, Naidoo V, Nikas SP, Shukla VG, Almeida MF, Byrd A, Romine H, Karanian DA, Makriyannis A, Bahr BA. Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Paraoxon. Journal of Molecular Neuroscience : Mn. PMID 28803438 DOI: 10.1007/S12031-017-0963-4 |
0.781 |
|
2017 |
Farizatto KLG, Ikonne US, Almeida MF, Ferrari MFR, Bahr BA. Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways. Plos One. 12: e0182895. PMID 28797057 DOI: 10.1371/journal.pone.0182895 |
0.459 |
|
2016 |
Smith M, Piehler T, Benjamin R, Farizatto KL, Pait MC, Almeida MF, Ghukasyan VV, Bahr BA. Blast waves from detonated military explosive reduce GluR1 and synaptophysin levels in hippocampal slice cultures. Experimental Neurology. PMID 27720798 DOI: 10.1016/j.expneurol.2016.10.002 |
0.467 |
|
2016 |
Carrasco DI, Bahr BA, Seburn KL, Pinter MJ. Abnormal response of distal Schwann cells to denervation in a mouse model of motor neuron disease. Experimental Neurology. PMID 26853136 DOI: 10.1016/j.expneurol.2016.02.002 |
0.324 |
|
2016 |
Pait MC, Elliott L, Hafner-Ruiz S, Mundell C, Patterson W, Romine H, Ikonne U, Bahr BA. Development of Cathepsin B Positive Modulators to Treat Multi‐Proteinopathic Dementias: Exploiting the Lysosomal Avenue of Protein Clearance to Promote Synaptic Recovery The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.707.1 |
0.344 |
|
2015 |
Maltecca F, Baseggio E, Consolato F, Mazza D, Podini P, Young SM, Drago I, Bahr BA, Puliti A, Codazzi F, Quattrini A, Casari G. Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model. The Journal of Clinical Investigation. 125: 263-74. PMID 25485680 DOI: 10.1172/JCI74770 |
0.381 |
|
2015 |
Bahr BA. A One-Drug Strategy is Needed to Attenuate the Multi-Proteinopathy that Leadsto Age-Related Diseases Journal of Gerontology and Geriatric Research. 2015: 1-2. DOI: 10.4172/2167-7182.1000212 |
0.318 |
|
2013 |
Hoffmann DB, Williams SK, Bojcevski J, Müller A, Stadelmann C, Naidoo V, Bahr BA, Diem R, Fairless R. Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. Journal of Neuropathology and Experimental Neurology. 72: 745-57. PMID 23860028 DOI: 10.1097/NEN.0b013e31829c7370 |
0.303 |
|
2013 |
Melo CV, Okumoto S, Gomes JR, Baptista MS, Bahr BA, Frommer WB, Duarte CB. Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons. Neuroscience. 237: 66-86. PMID 23384605 DOI: 10.1016/J.Neuroscience.2013.01.054 |
0.473 |
|
2013 |
Bahr BA. Lysosomal enhancement as a treatment for the multi-proteinopathy of Alzheimer?s disease and other protein accumulation disorders Journal of Neurology and Neurophysiology. DOI: 10.4172/2155-9562.S1.015 |
0.4 |
|
2012 |
Viswanathan K, Hoover DJ, Hwang J, Wisniewski ML, Ikonne US, Bahr BA, Wright DL. Nonpeptidic lysosomal modulators derived from z-phe-ala-diazomethylketone for treating protein accumulation diseases. Acs Medicinal Chemistry Letters. 3: 920-4. PMID 24900408 DOI: 10.1021/Ml300197H |
0.383 |
|
2012 |
Bahr BA, Wisniewski ML, Butler D. Positive lysosomal modulation as a unique strategy to treat age-related protein accumulation diseases. Rejuvenation Research. 15: 189-97. PMID 22533430 DOI: 10.1089/rej.2011.1282 |
0.457 |
|
2012 |
Naidoo V, Karanian DA, Vadivel SK, Locklear JR, Wood JT, Nasr M, Quizon PM, Graves EE, Shukla V, Makriyannis A, Bahr BA. Equipotent inhibition of fatty acid amide hydrolase and monoacylglycerol lipase - dual targets of the endocannabinoid system to protect against seizure pathology. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 801-13. PMID 22270809 DOI: 10.1007/S13311-011-0100-Y |
0.793 |
|
2011 |
Wisniewski ML, Hwang J, Bahr BA. Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner. Biochimica Et Biophysica Acta. 1812: 1664-74. PMID 21978994 DOI: 10.1016/j.bbadis.2011.09.011 |
0.445 |
|
2011 |
Lobo AC, Gomes JR, Catarino T, Mele M, Fernandez P, Inácio AR, Bahr BA, Santos AE, Wieloch T, Carvalho AL, Duarte CB. Cleavage of the vesicular glutamate transporters under excitotoxic conditions. Neurobiology of Disease. 44: 292-303. PMID 21807096 DOI: 10.1016/J.Nbd.2011.07.010 |
0.425 |
|
2011 |
Butler D, Hwang J, Estick C, Nishiyama A, Kumar SS, Baveghems C, Young-Oxendine HB, Wisniewski ML, Charalambides A, Bahr BA. Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models. Plos One. 6: e20501. PMID 21695208 DOI: 10.1371/Journal.Pone.0020501 |
0.422 |
|
2011 |
Naidoo V, Nikas SP, Karanian DA, Hwang J, Zhao J, Wood JT, Alapafuja SO, Vadivel SK, Butler D, Makriyannis A, Bahr BA. A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. Journal of Molecular Neuroscience : Mn. 43: 493-502. PMID 21069475 DOI: 10.1007/S12031-010-9472-4 |
0.793 |
|
2010 |
Baptista MS, Melo CV, Armelão M, Herrmann D, Pimentel DO, Leal G, Caldeira MV, Bahr BA, Bengtson M, Almeida RD, Duarte CB. Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons. Plos One. 5: e10139. PMID 20405034 DOI: 10.1371/Journal.Pone.0010139 |
0.444 |
|
2010 |
Zhu C, Hallin U, Ozaki Y, Grandér R, Gatzinsky K, Bahr BA, Karlsson JO, Shibasaki F, Hagberg H, Blomgren K. Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. Brain, Behavior, and Immunity. 24: 822-30. PMID 19782128 DOI: 10.1016/j.bbi.2009.09.013 |
0.35 |
|
2010 |
Hwang J, Adamson C, Butler D, Janero DR, Makriyannis A, Bahr BA. Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality. Life Sciences. 86: 615-23. PMID 19527737 DOI: 10.1016/J.Lfs.2009.06.003 |
0.463 |
|
2009 |
Bahr BA. Lysosomal modulatory drugs for a broad strategy against protein accumulation disorders. Current Alzheimer Research. 6: 438-45. PMID 19874268 DOI: 10.2174/156720509789207903 |
0.433 |
|
2008 |
Kanju PM, Parameshwaran K, Sims C, Bahr BA, Shonesy BC, Suppiramaniam V. Ampakine CX516 ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Experimental Neurology. 214: 55-61. PMID 18687330 DOI: 10.1016/j.expneurol.2008.07.010 |
0.725 |
|
2008 |
Pin SS, Bahr BA. Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists. European Journal of Pharmacology. 587: 8-15. PMID 18420188 DOI: 10.1016/J.Ejphar.2008.02.083 |
0.743 |
|
2008 |
Yu W, Charych EI, Serwanski DR, Li RW, Ali R, Bahr BA, De Blas AL. Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses. Journal of Neurochemistry. 105: 2300-14. PMID 18315564 DOI: 10.1111/j.1471-4159.2008.05311.x |
0.411 |
|
2008 |
Ryzhikov S, Bahr BA. Gephyrin alterations due to protein accumulation stress are reduced by the lysosomal modulator Z-Phe-Ala-diazomethylketone. Journal of Molecular Neuroscience : Mn. 34: 131-9. PMID 18204977 DOI: 10.1007/s12031-007-9009-7 |
0.5 |
|
2008 |
Araújo IM, Gil JM, Carreira BP, Mohapel P, Petersen A, Pinheiro PS, Soulet D, Bahr BA, Brundin P, Carvalho CM. Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus. Journal of Neurochemistry. 105: 666-76. PMID 18088374 DOI: 10.1111/J.1471-4159.2007.05181.X |
0.363 |
|
2008 |
Bahr BA, Butler D, Hwang J. P2-387: Lysosomal modulation reduces Aβ accumulation and promotes synaptic integrity and functional recovery in APPSwInd and APPswe/PS1dE9 mice Alzheimer's & Dementia. 4: T486-T486. DOI: 10.1016/j.jalz.2008.05.1465 |
0.331 |
|
2007 |
Pin SS, Xu C, Bahr BA. Desensitization and re-sensitization of CGRP receptor function in human neuroblastoma SK-N-MC cells. European Journal of Pharmacology. 577: 7-16. PMID 17825280 DOI: 10.1016/J.Ejphar.2007.08.014 |
0.742 |
|
2007 |
Kanju PM, Parameshwaran K, Vaithianathan T, Sims CM, Huggins K, Bendiske J, Ryzhikov S, Bahr BA, Suppiramaniam V. Lysosomal dysfunction produces distinct alterations in synaptic alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid and N-methyl-D-aspartate receptor currents in hippocampus. Journal of Neuropathology and Experimental Neurology. 66: 779-88. PMID 17805008 DOI: 10.1097/nen.0b013e3181461ae7 |
0.808 |
|
2007 |
Romanko MJ, Zhu C, Bahr BA, Blomgren K, Levison SW. Death effector activation in the subventricular zone subsequent to perinatal hypoxia/ischemia. Journal of Neurochemistry. 103: 1121-31. PMID 17711427 DOI: 10.1111/J.1471-4159.2007.04820.X |
0.311 |
|
2007 |
Li X, Serwanski DR, Miralles CP, Bahr BA, De Blas AL. Two pools of Triton X-100-insoluble GABA(A) receptors are present in the brain, one associated to lipid rafts and another one to the post-synaptic GABAergic complex. Journal of Neurochemistry. 102: 1329-45. PMID 17663755 DOI: 10.1111/j.1471-4159.2007.04635.x |
0.302 |
|
2007 |
Williams J, Wood J, Pandarinathan L, Karanian DA, Bahr BA, Vouros P, Makriyannis A. Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. Analytical Chemistry. 79: 5582-93. PMID 17600384 DOI: 10.1021/Ac0624086 |
0.717 |
|
2007 |
Araújo IM, Carreira BP, Pereira T, Santos PF, Soulet D, Inácio A, Bahr BA, Carvalho AP, Ambrósio AF, Carvalho CM. Changes in calcium dynamics following the reversal of the sodium-calcium exchanger have a key role in AMPA receptor-mediated neurodegeneration via calpain activation in hippocampal neurons. Cell Death and Differentiation. 14: 1635-46. PMID 17585341 DOI: 10.1038/sj.cdd.4402171 |
0.385 |
|
2007 |
Karanian DA, Karim SL, Wood JT, Williams JS, Lin S, Makriyannis A, Bahr BA. Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. The Journal of Pharmacology and Experimental Therapeutics. 322: 1059-66. PMID 17545313 DOI: 10.1124/Jpet.107.120147 |
0.779 |
|
2007 |
Kosten TA, Karanian DA, Yeh J, Haile CN, Kim JJ, Kehoe P, Bahr BA. Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience. Neurobiology of Learning and Memory. 88: 167-76. PMID 17543553 DOI: 10.1016/J.Nlm.2007.03.011 |
0.742 |
|
2007 |
Parameshwaran K, Sims C, Kanju P, Vaithianathan T, Shonesy BC, Dhanasekaran M, Bahr BA, Suppiramaniam V. Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function. Synapse (New York, N.Y.). 61: 367-74. PMID 17372971 DOI: 10.1002/Syn.20386 |
0.675 |
|
2007 |
Butler D, Bendiske J, Michaelis ML, Karanian DA, Bahr BA. Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. European Journal of Pharmacology. 562: 20-7. PMID 17336290 DOI: 10.1016/J.Ejphar.2007.01.053 |
0.798 |
|
2007 |
Mansouri B, Henne WM, Oomman SK, Bliss R, Attridge J, Finckbone V, Zeitouni T, Hoffman T, Bahr BA, Strahlendorf HK, Strahlendorf JC. Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons. European Journal of Pharmacology. 557: 106-14. PMID 17188264 DOI: 10.1016/J.Ejphar.2006.11.032 |
0.465 |
|
2007 |
Chicoine LM, Bahr BA. Excitotoxic protection by polyanionic polysaccharide: evidence of a cell survival pathway involving AMPA receptor-MAPK Interactions. Journal of Neuroscience Research. 85: 294-302. PMID 17131415 DOI: 10.1002/jnr.21117 |
0.489 |
|
2006 |
Karanian DA, Bahr BA. Cannabinoid drugs and enhancement of endocannabinoid responses: strategies for a wide array of disease states. Current Molecular Medicine. 6: 677-84. PMID 17022737 DOI: 10.2174/156652406778194991 |
0.763 |
|
2006 |
Suppiramaniam V, Vaithianathan T, Manivannan K, Dhanasekaran M, Parameshwaran K, Bahr BA. Modulatory effects of dextran sulfate and fucoidan on binding and channel properties of AMPA receptors isolated from rat brain. Synapse (New York, N.Y.). 60: 456-64. PMID 16897725 DOI: 10.1002/Syn.20319 |
0.649 |
|
2006 |
Karanian DA, Baude AS, Brown QB, Parsons CG, Bahr BA. 3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism. Hippocampus. 16: 834-42. PMID 16897723 DOI: 10.1002/Hipo.20214 |
0.792 |
|
2006 |
Butler D, Nixon RA, Bahr BA. Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases. Autophagy. 2: 234-7. PMID 16874061 DOI: 10.4161/Auto.2729 |
0.423 |
|
2006 |
Bahr BA, Karanian DA, Makanji SS, Makriyannis A. Targeting the endocannabinoid system in treating brain disorders. Expert Opinion On Investigational Drugs. 15: 351-65. PMID 16548785 DOI: 10.1517/13543784.15.4.351 |
0.767 |
|
2006 |
Butler D, Bahr BA. Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy. Antioxidants & Redox Signaling. 8: 185-96. PMID 16487052 DOI: 10.1089/ars.2006.8.185 |
0.342 |
|
2005 |
Butler D, Brown QB, Chin DJ, Batey L, Karim S, Mutneja MS, Karanian DA, Bahr BA. Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation. Rejuvenation Research. 8: 227-37. PMID 16313222 DOI: 10.1089/Rej.2005.8.227 |
0.796 |
|
2005 |
Karanian DA, Brown QB, Makriyannis A, Kosten TA, Bahr BA. Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7813-20. PMID 16120783 DOI: 10.1523/Jneurosci.2347-05.2005 |
0.792 |
|
2005 |
Volbracht C, Chua BT, Ng CP, Bahr BA, Hong W, Li P. The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide. Journal of Neurochemistry. 93: 1280-92. PMID 15934947 DOI: 10.1111/J.1471-4159.2005.03122.X |
0.363 |
|
2005 |
Araújo IM, Xapelli S, Gil JM, Mohapel P, Petersén A, Pinheiro PS, Malva JO, Bahr BA, Brundin P, Carvalho CM. Proteolysis of NR2B by calpain in the hippocampus of epileptic rats. Neuroreport. 16: 393-6. PMID 15729144 DOI: 10.1097/00001756-200503150-00017 |
0.425 |
|
2005 |
Karanian DA, Brown QB, Makriyannis A, Bahr BA. Blocking cannabinoid activation of FAK and ERK1/2 compromises synaptic integrity in hippocampus. European Journal of Pharmacology. 508: 47-56. PMID 15680253 DOI: 10.1016/J.Ejphar.2004.12.009 |
0.777 |
|
2005 |
Vaithianathan T, Manivannan K, Kleene R, Bahr BA, Dey MP, Dityatev A, Suppiramaniam V. Single channel recordings from synaptosomal AMPA receptors. Cell Biochemistry and Biophysics. 42: 75-85. PMID 15673930 DOI: 10.1385/Cbb:42:1:075 |
0.678 |
|
2005 |
Zhu C, Wang X, Xu F, Bahr BA, Shibata M, Uchiyama Y, Hagberg H, Blomgren K. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death and Differentiation. 12: 162-76. PMID 15592434 DOI: 10.1038/sj.cdd.4401545 |
0.341 |
|
2004 |
Araújo IM, Verdasca MJ, Leal EC, Bahr BA, Ambrósio AF, Carvalho AP, Carvalho CM. Early calpain-mediated proteolysis following AMPA receptor activation compromises neuronal survival in cultured hippocampal neurons. Journal of Neurochemistry. 91: 1322-31. PMID 15584909 DOI: 10.1111/j.1471-4159.2004.02811.x |
0.457 |
|
2004 |
Munirathinam S, Bahr BA. Repeated contact with subtoxic soman leads to synaptic vulnerability in hippocampus. Journal of Neuroscience Research. 77: 739-46. PMID 15352221 DOI: 10.1002/jnr.20209 |
0.448 |
|
2004 |
Vaithianathan T, Matthias K, Bahr B, Schachner M, Suppiramaniam V, Dityatev A, Steinhaüser C. Neural cell adhesion molecule-associated polysialic acid potentiates alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor currents. The Journal of Biological Chemistry. 279: 47975-84. PMID 15317811 DOI: 10.1074/Jbc.M407138200 |
0.686 |
|
2004 |
Caba E, Bahr BA. Biphasic NF-kappaB activation in the excitotoxic hippocampus. Acta Neuropathologica. 108: 173-82. PMID 15138780 DOI: 10.1007/S00401-004-0876-5 |
0.777 |
|
2004 |
Chicoine LM, Suppiramaniam V, Vaithianathan T, Gianutsos G, Bahr BA. Sulfate- and size-dependent polysaccharide modulation of AMPA receptor properties. Journal of Neuroscience Research. 75: 408-16. PMID 14743454 DOI: 10.1002/Jnr.10871 |
0.682 |
|
2004 |
Parameshwaran K, Vaithiyanathan T, Kanju PM, Bahr BA, Suppiramaniam V. P3-302 Amyloid β1–42 peptide potently modulates synaptic ampa receptor channel properties Neurobiology of Aging. 25: S441. DOI: 10.1016/S0197-4580(04)81452-0 |
0.656 |
|
2004 |
Bahr BA, Caba E. S4-03-05 Degenerative and compensatory pathways determine the level of synaptopathogenesis resulting from protein deposition Neurobiology of Aging. 25: S71. DOI: 10.1016/S0197-4580(04)80241-0 |
0.759 |
|
2003 |
Ekdahl CT, Zhu C, Bonde S, Bahr BA, Blomgren K, Lindvall O. Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival. Neurobiology of Disease. 14: 513-23. PMID 14678767 DOI: 10.1016/j.nbd.2003.08.022 |
0.356 |
|
2003 |
Ferrand-Drake M, Zhu C, Gidö G, Hansen AJ, Karlsson JO, Bahr BA, Zamzami N, Kroemer G, Chan PH, Wieloch T, Blomgren K. Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia. Journal of Neurochemistry. 85: 1431-42. PMID 12787063 DOI: 10.1046/J.1471-4159.2003.01794.X |
0.348 |
|
2003 |
Bendiske J, Bahr BA. Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease? Journal of Neuropathology and Experimental Neurology. 62: 451-63. PMID 12769185 DOI: 10.1093/Jnen/62.5.451 |
0.813 |
|
2002 |
Munirathinam S, Rogers G, Bahr BA. Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptors elicits neuroprotection after trimethyltin exposure in hippocampus. Toxicology and Applied Pharmacology. 185: 111-8. PMID 12490135 DOI: 10.1006/taap.2002.9534 |
0.496 |
|
2002 |
Ekdahl CT, Mohapel P, Weber E, Bahr B, Blomgren K, Lindvall O. Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus. The European Journal of Neuroscience. 16: 1463-71. PMID 12405959 DOI: 10.1046/j.1460-9568.2002.02202.x |
0.367 |
|
2002 |
Bahr BA, Bendiske J. The neuropathogenic contributions of lysosomal dysfunction. Journal of Neurochemistry. 83: 481-9. PMID 12390510 DOI: 10.1046/J.1471-4159.2002.01192.X |
0.782 |
|
2002 |
Bendiske J, Caba E, Brown QB, Bahr BA. Intracellular deposition, microtubule destabilization, and transport failure: an "early" pathogenic cascade leading to synaptic decline. Journal of Neuropathology and Experimental Neurology. 61: 640-50. PMID 12125743 DOI: 10.1093/Jnen/61.7.640 |
0.776 |
|
2002 |
Caba E, Brown QB, Kawasaki B, Bahr BA. Peptidyl alpha-keto amide inhibitor of calpain blocks excitotoxic damage without affecting signal transduction events. Journal of Neuroscience Research. 67: 787-94. PMID 11891793 DOI: 10.1002/Jnr.10163 |
0.794 |
|
2002 |
Bahr BA, Bendiske J, Brown QB, Munirathinam S, Caba E, Rudin M, Urwyler S, Sauter A, Rogers G. Survival signaling and selective neuroprotection through glutamatergic transmission. Experimental Neurology. 174: 37-47. PMID 11869032 DOI: 10.1006/Exnr.2001.7852 |
0.799 |
|
2001 |
Wang X, Karlsson JO, Zhu C, Bahr BA, Hagberg H, Blomgren K. Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. Biology of the Neonate. 79: 172-9. PMID 11275647 DOI: 10.1159/000047087 |
0.345 |
|
2001 |
Suppiramaniam V, Bahr BA, Sinnarajah S, Owens K, Rogers G, Yilma S, Vodyanoy V. Member of the Ampakine class of memory enhancers prolongs the single channel open time of reconstituted AMPA receptors. Synapse (New York, N.Y.). 40: 154-8. PMID 11252027 DOI: 10.1002/syn.1037 |
0.69 |
|
2001 |
Hoffman KB, Murray BA, Lynch G, Munirathinam S, Bahr BA. Delayed and isoform-specific effect of NMDA exposure on neural cell adhesion molecules in hippocampus. Neuroscience Research. 39: 167-73. PMID 11223462 DOI: 10.1016/S0168-0102(00)00214-5 |
0.413 |
|
2001 |
Rohn TT, Head E, Su JH, Anderson AJ, Bahr BA, Cotman CW, Cribbs DH. Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. The American Journal of Pathology. 158: 189-98. PMID 11141492 DOI: 10.1016/S0002-9440(10)63957-0 |
0.358 |
|
2001 |
Blomgren K, Zhu C, Wang X, Karlsson JO, Leverin AL, Bahr BA, Mallard C, Hagberg H. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"? The Journal of Biological Chemistry. 276: 10191-8. PMID 11124942 DOI: 10.1074/jbc.M007807200 |
0.347 |
|
2000 |
Vanderklish PW, Bahr BA. The pathogenic activation of calpain: a marker and mediator of cellular toxicity and disease states. International Journal of Experimental Pathology. 81: 323-39. PMID 11168679 DOI: 10.1046/j.1365-2613.2000.00169.x |
0.394 |
|
2000 |
Rohn TT, Ivins KJ, Bahr BA, Cotman CW, Cribbs DH. A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis. Journal of Neurochemistry. 74: 2331-42. PMID 10820193 DOI: 10.1046/j.1471-4159.2000.0742331.x |
0.359 |
|
2000 |
Bahr BA. Integrin-type signaling has a distinct influence on NMDA-induced cytoskeletal disassembly. Journal of Neuroscience Research. 59: 827-32. PMID 10700020 DOI: 10.1002/(SICI)1097-4547(20000315)59:6<827::AID-JNR15>3.0.CO;2-Q |
0.48 |
|
1999 |
Sabatini DM, Barrow RK, Blackshaw S, Burnett PE, Lai MM, Field ME, Bahr BA, Kirsch J, Betz H, Snyder SH. Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science (New York, N.Y.). 284: 1161-4. PMID 10325225 DOI: 10.1126/Science.284.5417.1161 |
0.365 |
|
1999 |
Blomgren K, Hallin U, Andersson AL, Puka-Sundvall M, Bahr BA, McRae A, Saido TC, Kawashima S, Hagberg H. Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia. The Journal of Biological Chemistry. 274: 14046-52. PMID 10318818 DOI: 10.1074/jbc.274.20.14046 |
0.353 |
|
1999 |
Sinnarajah S, Suppiramaniam V, Kumar KP, Hall RA, Bahr BA, Vodyanoy V. Heparin modulates the single channel kinetics of reconstituted AMPA receptors from rat brain. Synapse (New York, N.Y.). 31: 203-9. PMID 10029238 DOI: 10.1002/(SICI)1098-2396(19990301)31:3<203::AID-SYN5>3.0.CO;2-W |
0.654 |
|
1998 |
Hoffman KB, Larson J, Bahr BA, Lynch G. Activation of NMDA receptors stimulates extracellular proteolysis of cell adhesion molecules in hippocampus. Brain Research. 811: 152-5. PMID 9804935 DOI: 10.1016/S0006-8993(98)00907-X |
0.448 |
|
1998 |
Bahr BA, Hoffman KB, Yang AJ, Hess US, Glabe CG, Lynch G. Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein. The Journal of Comparative Neurology. 397: 139-47. PMID 9671284 DOI: 10.1002/(Sici)1096-9861(19980720)397:1<139::Aid-Cne10>3.0.Co;2-K |
0.379 |
|
1998 |
Bahr BA, Vicente JS. Age-related phosphorylation and fragmentation events influence the distribution profiles of distinct tau isoforms in mouse brain. Journal of Neuropathology and Experimental Neurology. 57: 111-21. PMID 9600203 DOI: 10.1097/00005072-199802000-00002 |
0.324 |
|
1997 |
Edelstein CL, Ling H, Gengaro PE, Nemenoff RA, Bahr BA, Schrier RW. Effect of glycine on prelethal and postlethal increases in calpain activity in rat renal proximal tubules. Kidney International. 52: 1271-8. PMID 9350650 DOI: 10.1038/Ki.1997.452 |
0.374 |
|
1997 |
Kawasaki BT, Hoffman KB, Yamamoto RS, Bahr BA. Variants of the receptor/channel clustering molecule gephyrin in brain: distinct distribution patterns, developmental profiles, and proteolytic cleavage by calpain. Journal of Neuroscience Research. 49: 381-8. PMID 9260749 DOI: 10.1002/(SICI)1097-4547(19970801)49:3<381::AID-JNR13>3.0.CO;2-2 |
0.397 |
|
1997 |
Capaldi D, Rosario R, Esteban ET, Bahr BA. A 27-kDa matrix receptor from rat brain synaptosomes: selective recognition of the Arg-Gly-Asp-Ser domain and unique resistance to calcium-dependent proteolysis. Neuroscience Research. 28: 275-9. PMID 9237276 DOI: 10.1016/S0168-0102(97)00049-7 |
0.372 |
|
1997 |
Bahr BA, Staubli U, Xiao P, Chun D, Ji Z, Esteban ET, Lynch G. Arg-Gly-Asp-Ser-Selective Adhesion and the Stabilization of Long-Term Potentiation: Pharmacological Studies and the Characterization of a Candidate Matrix Receptor The Journal of Neuroscience. 17: 1320-1329. DOI: 10.1523/JNEUROSCI.17-04-01320.1997 |
0.41 |
|
1996 |
Hall RA, Vodyanoy V, Quan A, Sinnarajah S, Suppiramaniam V, Kessler M, Bahr BA. Effects of heparin on the properties of solubilized and reconstituted rat brain AMPA receptors. Neuroscience Letters. 217: 179-83. PMID 8916102 DOI: 10.1016/0304-3940(96)12984-0 |
0.663 |
|
1996 |
Bahr BA, Hoffman KB, Kessler M, Hennegriff M, Park GY, Yamamoto RS, Kawasaki BT, Vanderklish PW, Hall RA, Lynch G. Distinct distributions of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunits and a related 53,000 M(R) antigen (GR53) in brain tissue. Neuroscience. 74: 707-21. PMID 8884767 DOI: 10.1016/0306-4522(96)00133-9 |
0.397 |
|
1995 |
Bednarski E, Vanderklish P, Gall C, Saido TC, Bahr BA, Lynch G. Translational suppression of calpain I reduces NMDA-induced spectrin proteolysis and pathophysiology in cultured hippocampal slices. Brain Research. 694: 147-57. PMID 8974639 DOI: 10.1016/0006-8993(95)00851-G |
0.438 |
|
1995 |
Bahr BA, Kessler M, Rivera S, Vanderklish PW, Hall RA, Mutneja MS, Gall C, Hoffman KB. Stable maintenance of glutamate receptors and other synaptic components in long-term hippocampal slices. Hippocampus. 5: 425-39. PMID 8773255 DOI: 10.1002/hipo.450050505 |
0.473 |
|
1995 |
Bahr BA. Long-term hippocampal slices: a model system for investigating synaptic mechanisms and pathologic processes. Journal of Neuroscience Research. 42: 294-305. PMID 8583497 DOI: 10.1002/jnr.490420303 |
0.391 |
|
1995 |
Bahr BA, Tiriveedhi S, Park GY, Lynch G. Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices. The Journal of Pharmacology and Experimental Therapeutics. 273: 902-8. PMID 7538583 |
0.378 |
|
1994 |
del Cerro S, Arai A, Kessler M, Bahr BA, Vanderklish P, Rivera S, Lynch G. Stimulation of NMDA receptors activates calpain in cultured hippocampal slices. Neuroscience Letters. 167: 149-52. PMID 8177514 DOI: 10.1016/0304-3940(94)91049-9 |
0.423 |
|
1994 |
Bahr BA, Lam N, Lynch G. Changes in the concentrations of tau and other structural proteins in the brains of aged mice. Neuroscience Letters. 175: 49-52. PMID 7970209 DOI: 10.1016/0304-3940(94)91075-8 |
0.321 |
|
1994 |
Hall RA, Bahr BA. AMPA receptor development in rat telencephalon: [3H]AMPA binding and western blot studies. Journal of Neurochemistry. 63: 1658-65. PMID 7931321 DOI: 10.1046/J.1471-4159.1994.63051658.X |
0.367 |
|
1994 |
Bahr BA, Abai B, Gall CM, Vanderklish PW, Hoffman KB, Lynch G. Induction of beta-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin. Experimental Neurology. 129: 81-94. PMID 7925845 DOI: 10.1006/exnr.1994.1149 |
0.46 |
|
1994 |
Bahr BA, Neve RL, Sharp J, Geller AI, Lynch G. Rapid and stable gene expression in hippocampal slice cultures from a defective HSV-1 vector. Brain Research. Molecular Brain Research. 26: 277-85. PMID 7531803 DOI: 10.1016/0169-328X(94)90100-7 |
0.309 |
|
1993 |
Bahr BA, Godshall AC, Murray BA, Lynch G. Age-related changes in neural cell adhesion molecule (NCAM) isoforms in the mouse telencephalon. Brain Research. 628: 286-92. PMID 8313157 DOI: 10.1016/0006-8993(93)90966-Q |
0.348 |
|
1993 |
Vodyanoy V, Bahr BA, Suppiramaniam V, Hall RA, Baudry M, Lynch G. Single channel recordings of reconstituted AMPA receptors reveal low and high conductance states. Neuroscience Letters. 150: 80-4. PMID 7682309 DOI: 10.1016/0304-3940(93)90113-Y |
0.671 |
|
1993 |
Neve RL, Ivins KJ, Neve KA, Bahr BA, Vanderklish PW, Arai A, Lynch G. The Use of Antisense Intervention to Decipher the Role of the Neuronal Growth-Associated Protein GAP-43 Neuroprotocols. 2: 39-49. DOI: 10.1006/Ncmn.1993.1007 |
0.332 |
|
1992 |
Vanderklish P, Neve R, Bahr BA, Arai A, Hennegriff M, Larson J, Lynch G. Translational suppression of a glutamate receptor subunit impairs long-term potentiation. Synapse (New York, N.Y.). 12: 333-7. PMID 1465743 DOI: 10.1002/Syn.890120410 |
0.378 |
|
1992 |
Bahr BA, Vodyanoy V, Hall RA, Suppiramaniam V, Kessler M, Sumikawa K, Lynch G. Functional reconstitution of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors from rat brain. Journal of Neurochemistry. 59: 1979-82. PMID 1383430 DOI: 10.1111/j.1471-4159.1992.tb11038.x |
0.674 |
|
1992 |
Bahr BA, Godshall AC, Hall RA, Lynch G. Mouse telencephalon exhibits an age-related decrease in glutamate (AMPA) receptors but no change in nerve terminal markers. Brain Research. 589: 320-6. PMID 1327416 DOI: 10.1016/0006-8993(92)91293-N |
0.429 |
|
1991 |
Xiao P, Bahr BA, Staubli U, Vanderklish PW, Lynch G. Evidence that matrix recognition contributes to stabilization but not induction of LTP. Neuroreport. 2: 461-4. PMID 1912480 DOI: 10.1097/00001756-199108000-00013 |
0.319 |
|
1991 |
Sheppard A, Wu J, Bahr BA, Lynch G. Compartmentation and glycoprotein substrates of calpain in the developing rat brain. Synapse (New York, N.Y.). 9: 231-4. PMID 1776133 DOI: 10.1002/syn.890090310 |
0.37 |
|
1991 |
Bahr BA, Sheppard A, Lynch G. Fibronectin binding by brain synaptosomal membranes may not involve conventional integrins. Neuroreport. 2: 13-6. PMID 1768843 DOI: 10.1097/00001756-199101000-00003 |
0.36 |
|
1991 |
Bahr BA, Vanderklish PW, Ha LT, Tin MT, Lynch G. Spectrin breakdown products increase with age in telencephalon of mouse brain. Neuroscience Letters. 131: 237-40. PMID 1762696 DOI: 10.1016/0304-3940(91)90622-Z |
0.302 |
|
1989 |
Rogers GA, Parsons SM, Anderson DC, Nilsson LM, Bahr BA, Kornreich WD, Kaufman R, Jacobs RS, Kirtman B. Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogues of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol). Journal of Medicinal Chemistry. 32: 1217-30. PMID 2724295 DOI: 10.1021/Jm00126A013 |
0.305 |
|
1986 |
Bahr BA, Parsons SM. Demonstration of a receptor in Torpedo synaptic vesicles for the acetylcholine storage blocker L-trans-2-(4-phenyl[3,4-3H]-piperidino) cyclohexanol. Proceedings of the National Academy of Sciences of the United States of America. 83: 2267-70. PMID 3457385 DOI: 10.1073/Pnas.83.7.2267 |
0.314 |
|
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