Andy Y. Shih, Ph.D. - Publications

Affiliations: 
Neurophysics University of California, San Diego, La Jolla, CA 
Area:
Vascular system

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Watson AN, Berthiaume AA, Faino AV, McDowell KP, Bhat NR, Hartmann DA, Shih AY. Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19900543. PMID 31987006 DOI: 10.1177/0271678X19900543  1
2019 O'Herron P, Summers PM, Shih AY, Kara P, Woodward JJ. In Vivo Two-Photon Imaging of Neuronal and Brain Vascular Responses in Mice Chronically Exposed to Ethanol. Alcohol (Fayetteville, N.Y.). PMID 31857103 DOI: 10.1016/j.alcohol.2019.12.001  1
2019 Berthiaume AA, Shih AY. Sharpening the tools for pericyte research. Nature Neuroscience. 22: 1041-1043. PMID 31235904 DOI: 10.1038/s41593-019-0437-9  1
2018 Berthiaume AA, Hartmann DA, Majesky MW, Bhat NR, Shih AY. Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis. Frontiers in Aging Neuroscience. 10: 210. PMID 30065645 DOI: 10.3389/fnagi.2018.00210  1
2018 Shih AY, Hyacinth HI, Hartmann DA, van Veluw SJ. Rodent Models of Cerebral Microinfarct and Microhemorrhage. Stroke. PMID 29459393 DOI: 10.1161/STROKEAHA.117.016995  0.96
2018 Berthiaume AA, Grant RI, McDowell KP, Underly RG, Hartmann DA, Levy M, Bhat NR, Shih AY. Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain. Cell Reports. 22: 8-16. PMID 29298435 DOI: 10.1016/j.celrep.2017.12.016  1
2017 Mateo C, Knutsen PM, Tsai PS, Shih AY, Kleinfeld D. Entrainment of Arteriole Vasomotor Fluctuations by Neural Activity Is a Basis of Blood-Oxygenation-Level-Dependent "Resting-State" Connectivity. Neuron. PMID 29107517 DOI: 10.1016/j.neuron.2017.10.012  1
2017 Hartmann DA, Hyacinth HI, Liao FF, Shih AY. Does pathology of small venules contribute to cerebral microinfarcts and dementia? Journal of Neurochemistry. PMID 28950410 DOI: 10.1111/jnc.14228  0.96
2017 Grant RI, Hartmann DA, Underly RG, Berthiaume AA, Bhat NR, Shih AY. Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17732229. PMID 28933255 DOI: 10.1177/0271678X17732229  1
2017 Hyacinth HI, Sugihara CL, Spencer TL, Archer DR, Shih AY. Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17732275. PMID 28925802 DOI: 10.1177/0271678X17732275  0.32
2017 Underly RG, Shih AY. Photothrombotic Induction of Capillary Ischemia in the Mouse Cortex during in vivo Two-photon Imaging. Bio-Protocol. 7. PMID 28835908 DOI: 10.21769/BioProtoc.2378  1
2017 Summers PM, Hartmann DA, Hui ES, Nie X, Deardorff RL, McKinnon ET, Helpern JA, Jensen JH, Shih AY. Functional deficits induced by cortical microinfarcts. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X16685573. PMID 28090802 DOI: 10.1177/0271678X16685573  1
2017 Underly RG, Levy M, Hartmann DA, Grant RI, Watson AN, Shih AY. Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 129-140. PMID 28053036 DOI: 10.1523/JNEUROSCI.2891-16.2017  1
2015 Taylor ZJ, Hui ES, Watson AN, Nie X, Deardorff RL, Jensen JH, Helpern JA, Shih AY. Microvascular basis for growth of small infarcts following occlusion of single penetrating arterioles in mouse cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661182 DOI: 10.1177/0271678X15608388  1
2015 Hartmann DA, Underly RG, Grant RI, Watson AN, Lindner V, Shih AY. Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice. Neurophotonics. 2: 041402. PMID 26158016 DOI: 10.1117/1.NPh.2.4.041402  1
2015 Shih AY, Rühlmann C, Blinder P, Devor A, Drew PJ, Friedman B, Knutsen PM, Lyden PD, Matéo C, Mellander L, Nishimura N, Schaffer CB, Tsai PS, Kleinfeld D. Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Microcirculation (New York, N.Y. : 1994). 22: 204-18. PMID 25705966 DOI: 10.1111/micc.12195  1
2015 Hartmann DA, Underly RG, Watson AN, Shih AY. A murine toolbox for imaging the neurovascular unit. Microcirculation (New York, N.Y. : 1994). 22: 168-82. PMID 25352367 DOI: 10.1111/micc.12176  1
2014 Summers PM, Taylor ZJ, Shih AY. Two-photon imaging of cerebral vasodynamics in awake mice during health and disease Advances in Intravital Microscopy: From Basic to Clinical Research. 25-43. DOI: 10.1007/978-94-017-9361-2_2  1
2014 Shih AY, Driscoll JD, Pesavento MJ, Kleinfeld D. Two-photon microscopy to measure blood flow and concurrent brain cell activity Neuromethods. 85: 273-290. DOI: 10.1007/978-1-62703-785-3_16  1
2014 Shih AY, Drew PJ, Kleinfeld D. Imaging vasodynamics in the Awake mouse brain with two-photon microscopy Neuromethods. 88: 55-73. DOI: 10.1007/978-1-4939-0724-3_4  1
2013 Taylor ZJ, Shih AY. Targeted Occlusion of Individual Pial Vessels of Mouse Cortex. Bio-Protocol. 3. PMID 27547784  1
2013 Shih AY, Nishimura N, Nguyen J, Friedman B, Lyden PD, Schaffer CB, Kleinfeld D. Optically induced occlusion of single blood vessels in rodent neocortex. Cold Spring Harbor Protocols. 2013: 1153-60. PMID 24298038 DOI: 10.1101/pdb.prot079509  1
2013 Driscoll JD, Shih AY, Drew PJ, Cauwenberghs G, Kleinfeld D. Two-photon imaging of blood flow in the rat cortex. Cold Spring Harbor Protocols. 2013: 759-67. PMID 23906919 DOI: 10.1101/pdb.prot076513  1
2013 Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D. The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nature Neuroscience. 16: 55-63. PMID 23242312 DOI: 10.1038/nn.3278  1
2012 Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D. A polished and reinforced thinned-skull window for long-term imaging of the mouse brain. Journal of Visualized Experiments : Jove. PMID 22433225 DOI: 10.3791/3742  1
2012 Shih AY, Driscoll JD, Drew PJ, Nishimura N, Schaffer CB, Kleinfeld D. Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1277-309. PMID 22293983 DOI: 10.1038/jcbfm.2011.196  1
2011 Kleinfeld D, Blinder P, Drew PJ, Driscoll JD, Muller A, Tsai PS, Shih AY. A guide to delineate the logic of neurovascular signaling in the brain. Frontiers in Neuroenergetics. 3: 1. PMID 21559095 DOI: 10.3389/fnene.2011.00001  1
2011 Drew PJ, Shih AY, Kleinfeld D. Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8473-8. PMID 21536897 DOI: 10.1073/pnas.1100428108  1
2011 Driscoll JD, Shih AY, Iyengar S, Field JJ, White GA, Squier JA, Cauwenberghs G, Kleinfeld D. Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy. Journal of Neurophysiology. 105: 3106-13. PMID 21471395 DOI: 10.1152/jn.00649.2010  1
2010 Drew PJ, Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai PS, Kleinfeld D. Chronic optical access through a polished and reinforced thinned skull. Nature Methods. 7: 981-4. PMID 20966916 DOI: 10.1038/nmeth.1530  1
2010 Blinder P, Shih AY, Rafie C, Kleinfeld D. Topological basis for the robust distribution of blood to rodent neocortex. Proceedings of the National Academy of Sciences of the United States of America. 107: 12670-5. PMID 20616030 DOI: 10.1073/pnas.1007239107  1
2010 Valmianski I, Shih AY, Driscoll JD, Matthews DW, Freund Y, Kleinfeld D. Automatic identification of fluorescently labeled brain cells for rapid functional imaging. Journal of Neurophysiology. 104: 1803-11. PMID 20610792 DOI: 10.1152/jn.00484.2010  1
2010 Drew PJ, Blinder P, Cauwenberghs G, Shih AY, Kleinfeld D. Rapid determination of particle velocity from space-time images using the Radon transform. Journal of Computational Neuroscience. 29: 5-11. PMID 19459038 DOI: 10.1007/s10827-009-0159-1  1
2010 Devor A, Shih AY, Tsai PS, Blinder P, Tian P, Teng IC, Kleinfeld D. Two-photon laser scanning microscopy as a tool to study cortical vasodynamics under normal and ischemic conditions Imaging the Brain With Optical Methods. 245-261. DOI: 10.1007/978-1-4419-0452-2_11  1
2009 Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. The Journal of Clinical Investigation. 119: 3373-83. PMID 19809162 DOI: 10.1172/JCI39378  1
2009 Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. Acute vascular disruption and aquaporin 4 loss after stroke. Stroke; a Journal of Cerebral Circulation. 40: 2182-90. PMID 19372455 DOI: 10.1161/STROKEAHA.108.523720  1
2009 Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 738-51. PMID 19174826 DOI: 10.1038/jcbfm.2008.166  1
2009 Tsai PS, Blinder P, Drew P, Driscoll J, Jeong D, Kaufhold JP, Shih A, Valmianski I, Kleinfeld D. Topology, dynamics, and control in cortical blood flow elucidated with optical techniques Proceedings of Spie - the International Society For Optical Engineering. 7397. DOI: 10.1117/12.829588  1
2009 Kleinfeld D, Friedman B, Lyden PD, Shih AY. Targeted occlusion to surface and deep vessels in neocortex via linear and nonlinear optical absorption Animal Models of Acute Neurological Injuries. 169-185. DOI: 10.1007/978-1-60327-185-1_14  1
2007 Shih AY, Erb H, Murphy TH. Dopamine activates Nrf2-regulated neuroprotective pathways in astrocytes and meningeal cells. Journal of Neurochemistry. 101: 109-19. PMID 17394461 DOI: 10.1111/j.1471-4159.2006.04345.x  1
2007 Pacchioni AM, Vallone J, Melendez RI, Shih A, Murphy TH, Kalivas PW. Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity. Brain Research. 1127: 26-35. PMID 17113054 DOI: 10.1016/j.brainres.2006.10.036  1
2006 Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10514-23. PMID 17035536 DOI: 10.1523/JNEUROSCI.3178-06.2006  1
2006 Sun X, Shih AY, Johannssen HC, Erb H, Li P, Murphy TH. Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface. The Journal of Biological Chemistry. 281: 17420-31. PMID 16624809 DOI: 10.1074/jbc.M601567200  1
2006 Shih AY, Fernandes HB, Choi FY, Kozoriz MG, Liu Y, Li P, Cowan CM, Klegeris A. Policing the police: astrocytes modulate microglial activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3887-8. PMID 16611803 DOI: 10.1523/JNEUROSCI.0936-06.2006  1
2005 Shih AY, Li P, Murphy TH. A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10321-35. PMID 16267240 DOI: 10.1523/JNEUROSCI.4014-05.2005  1
2005 Shih AY, Imbeault S, Barakauskas V, Erb H, Jiang L, Li P, Murphy TH. Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. The Journal of Biological Chemistry. 280: 22925-36. PMID 15840590 DOI: 10.1074/jbc.M414635200  1
2003 Lee JM, Shih AY, Murphy TH, Johnson JA. NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. The Journal of Biological Chemistry. 278: 37948-56. PMID 12842875 DOI: 10.1074/jbc.M305204200  1
2003 Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, Murphy TH. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3394-406. PMID 12716947  1
2001 Shih AY, Murphy TH. xCt cystine transporter expression in HEK293 cells: pharmacology and localization. Biochemical and Biophysical Research Communications. 282: 1132-7. PMID 11302733 DOI: 10.1006/bbrc.2001.4703  1
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