Nathaniel Heintz - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Moya MV, Kim RD, Rao MN, Cotto BA, Pickett SB, Sferrazza CE, Heintz N, Schmidt EF. Unique molecular features and cellular responses differentiate two populations of motor cortical layer 5b neurons in a preclinical model of ALS. Cell Reports. 38: 110556. PMID 35320722 DOI: 10.1016/j.celrep.2022.110556  0.796
2022 Montalban E, Giralt A, Taing L, Schut EHS, Supiot LF, Castell L, Nakamura Y, de Pins B, Pelosi A, Goutebroze L, Tuduri P, Wang W, Neiburga KD, Vestito L, Castel J, ... ... Heintz N, et al. Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects. Molecular Psychiatry. PMID 35177825 DOI: 10.1038/s41380-022-01439-4  0.484
2021 Karayol R, Medrihan L, Warner-Schmidt JL, Fait BW, Rao MN, Holzner EB, Greengard P, Heintz N, Schmidt EF. Serotonin receptor 4 in the hippocampus modulates mood and anxiety. Molecular Psychiatry. PMID 33441982 DOI: 10.1038/s41380-020-00994-y  0.623
2020 Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E. Amygdala inhibitory neurons as loci for translation in emotional memories. Nature. PMID 33029009 DOI: 10.1038/s41586-020-2793-8  0.64
2020 Roussarie JP, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, Kasturia S, Albornoz C, Wang W, Schmidt EF, Dannenfelser R, Tadych A, Brichta L, Barnea-Cramer A, Heintz N, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. PMID 32603655 DOI: 10.1016/J.Neuron.2020.06.010  0.564
2020 Antolin-Fontes B, Li K, Ables JL, Riad MH, Görlich A, Williams M, Wang C, Lipford SM, Dao M, Liu J, Molina H, Heintz N, Kenny PJ, Ibañez-Tallon I. The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. PMID 32098843 DOI: 10.1073/Pnas.1916132117  0.752
2020 Shrestha P, Ayata P, Herrero-Vidal P, Longo F, Gastone A, LeDoux JE, Heintz N, Klann E. Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation. Nature Neuroscience. PMID 31959934 DOI: 10.1038/S41593-019-0568-Z  0.642
2019 Piccolo FM, Liu Z, Dong P, Hsu C, Stoyanova EI, Rao A, Tjian R, Heintz N. Author response: MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions Elife. DOI: 10.7554/Elife.51449.Sa2  0.304
2018 Xu X, Stoyanova EI, Lemiesz AE, Xing J, Mash DC, Heintz N. Species and cell-type properties of classically defined human and rodent neurons and glia. Elife. 7. PMID 30320555 DOI: 10.7554/Elife.37551  0.305
2018 Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell Reports. 23: 2225-2235. PMID 29791834 DOI: 10.1016/J.Celrep.2018.04.054  0.773
2018 Nakayama H, Ibañez-Tallon I, Heintz N. Cell-type specific contributions of medial prefrontal neurons to flexible behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29650697 DOI: 10.1523/JNEUROSCI.3537-17.2018  0.7
2018 Xu X, Stoyanova EI, Lemiesz AE, Xing J, Mash DC, Heintz N. Author response: Species and cell-type properties of classically defined human and rodent neurons and glia Elife. DOI: 10.7554/Elife.37551.041  0.341
2017 Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/Pnas.1717506114  0.75
2017 Mellén M, Ayata P, Heintz N. 5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847947 DOI: 10.1073/pnas.1708044114  0.771
2017 Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/J.Celrep.2017.03.048  0.59
2016 Li K, Nakajima M, Ibañez-Tallon I, Heintz N. A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. PMID 27641503 DOI: 10.1016/J.Cell.2016.08.067  0.722
2015 Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G. Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12869-89. PMID 26377473 DOI: 10.1523/Jneurosci.1164-15.2015  0.534
2015 Shrestha P, Mousa A, Heintz N. Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors. Elife. 4. PMID 26371510 DOI: 10.7554/Elife.08752  0.432
2015 Shrestha P, Mousa A, Heintz N. Author response: Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors Elife. DOI: 10.7554/Elife.08752.014  0.491
2014 Nakajima M, Görlich A, Heintz N. Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons. Cell. 159: 295-305. PMID 25303526 DOI: 10.1016/J.Cell.2014.09.020  0.57
2014 McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/Journal.Pgen.1004626  0.351
2014 Anthony TE, Dee N, Bernard A, Lerchner W, Heintz N, Anderson DJ. Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell. 156: 522-36. PMID 24485458 DOI: 10.1016/J.Cell.2013.12.040  0.78
2013 Gerfen CR, Paletzki R, Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron. 80: 1368-83. PMID 24360541 DOI: 10.1016/j.neuron.2013.10.016  0.341
2013 Fishell G, Heintz N. The neuron identity problem: form meets function. Neuron. 80: 602-12. PMID 24183013 DOI: 10.1016/j.neuron.2013.10.035  0.402
2013 Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF. Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. Plos One. 8: e69208. PMID 23861962 DOI: 10.1371/Journal.Pone.0069208  0.402
2013 Lanoue V, Usardi A, Sigoillot SM, Talleur M, Iyer K, Mariani J, Isope P, Vodjdani G, Heintz N, Selimi F. The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons. Molecular Psychiatry. 18: 943-50. PMID 23628982 DOI: 10.1038/Mp.2013.46  0.411
2013 Schmidt EF, Kus L, Gong S, Heintz N. BAC transgenic mice and the GENSAT database of engineered mouse strains. Cold Spring Harbor Protocols. 2013. PMID 23457350 DOI: 10.1101/pdb.top073692  0.635
2013 Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD. Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes & Development. 27: 565-78. PMID 23431030 DOI: 10.1101/Gad.207654.112  0.427
2013 Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2732-53. PMID 23407934 DOI: 10.1523/Jneurosci.4762-12.2013  0.401
2012 Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell. 151: 1417-30. PMID 23260135 DOI: 10.1016/J.Cell.2012.11.022  0.4
2012 Dougherty JD, Zhang J, Feng H, Gong S, Heintz N. Mouse transgenesis in a single locus with independent regulation for multiple fluorophores. Plos One. 7: e40511. PMID 22808177 DOI: 10.1371/Journal.Pone.0040511  0.372
2012 Heller EA, Zhang W, Selimi F, Earnheart JC, ?limak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N. The biochemical anatomy of cortical inhibitory synapses. Plos One. 7: e39572. PMID 22768092 DOI: 10.1371/Journal.Pone.0039572  0.731
2012 Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ. Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9124-32. PMID 22764222 DOI: 10.1523/Jneurosci.0229-12.2012  0.316
2012 Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/Pnas.1209293109  0.772
2012 Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N. Identification of the cortical neurons that mediate antidepressant responses. Cell. 149: 1152-63. PMID 22632977 DOI: 10.1016/J.Cell.2012.03.038  0.789
2012 Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR. Reprogramming axonal behavior by axon-specific viral transduction. Gene Therapy. 19: 947-55. PMID 22278412 DOI: 10.1038/Gt.2011.217  0.55
2011 Yang Z, Jiang H, Chaichanasakul T, Gong S, Yang XW, Heintz N, Lin S. Corrigendum to " Modified bacterial artificial chromosomes for zebrafish transgenesis" Methods 39 (2006) 183-188 Methods. 53: 327. DOI: 10.1016/J.Ymeth.2010.11.001  0.417
2010 Morishita H, Miwa JM, Heintz N, Hensch TK. Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (New York, N.Y.). 330: 1238-40. PMID 21071629 DOI: 10.1126/Science.1195320  0.705
2010 Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468: 263-9. PMID 21068835 DOI: 10.1038/Nature09582  0.329
2010 Gong S, Kus L, Heintz N. Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nature Protocols. 5: 1678-96. PMID 20885380 DOI: 10.1038/nprot.2010.131  0.324
2010 Dougherty JD, Schmidt EF, Nakajima M, Heintz N. Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Research. 38: 4218-30. PMID 20308160 DOI: 10.1093/Nar/Gkq130  0.701
2010 Groh A, Meyer HS, Schmidt EF, Heintz N, Sakmann B, Krieger P. Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cerebral Cortex (New York, N.Y. : 1991). 20: 826-36. PMID 19643810 DOI: 10.1093/Cercor/Bhp152  0.579
2009 Siegert S, Scherf BG, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address book for retinal cell types. Nature Neuroscience. 12: 1197-204. PMID 19648912 DOI: 10.1038/nn.2370  0.387
2009 Selimi F, Cristea IM, Heller E, Chait BT, Heintz N. Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. Plos Biology. 7: e83. PMID 19402746 DOI: 10.1371/Journal.Pbio.1000083  0.543
2009 Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (New York, N.Y.). 324: 929-30. PMID 19372393 DOI: 10.1126/science.1169786  0.383
2009 Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 4477-82. PMID 19246390 DOI: 10.1073/Pnas.0813109106  0.779
2009 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types (DOI:10.1016/j.cell.2008.10.029) Cell. 139: 1022. DOI: 10.1016/j.cell.2009.11.011  0.773
2008 Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Research : Official Journal of the International Society For Autism Research. 1: 147-58. PMID 19360662 DOI: 10.1002/Aur.22  0.308
2008 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 135: 749-62. PMID 19013282 DOI: 10.1016/J.Cell.2008.10.029  0.786
2008 Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell. 135: 738-48. PMID 19013281 DOI: 10.1016/J.Cell.2008.10.028  0.419
2008 Anthony TE, Heintz N. Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Development. 3: 30. PMID 18986511 DOI: 10.1186/1749-8104-3-30  0.75
2008 Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/J.Neuron.2008.09.009  0.704
2008 Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10460-71. PMID 18923023 DOI: 10.1523/Jneurosci.2518-08.2008  0.315
2008 Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nature Neuroscience. 11: 932-9. PMID 18622401 DOI: 10.1038/Nn.2153  0.343
2007 Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9817-23. PMID 17855595 DOI: 10.1523/JNEUROSCI.2707-07.2007  0.368
2007 Gorokhova S, Bibert S, Geering K, Heintz N. A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase. Human Molecular Genetics. 16: 2394-410. PMID 17606467 DOI: 10.1093/Hmg/Ddm167  0.647
2007 Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S, Vaughan M, Hicks DG, Heintz N, Cowell JK. Defining the expression pattern of the LGI1 gene in BAC transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 328-37. PMID 17565425 DOI: 10.1007/s00335-007-9024-6  0.367
2007 Chang SY, Zagha E, Kwon ES, Ozaita A, Bobik M, Martone ME, Ellisman MH, Heintz N, Rudy B. Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain. The Journal of Comparative Neurology. 502: 953-72. PMID 17444489 DOI: 10.1002/Cne.21353  0.397
2007 Anthony TE, Heintz N. The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. The Journal of Comparative Neurology. 500: 368-83. PMID 17111379 DOI: 10.1002/Cne.21179  0.754
2007 Heintz N, Hatten ME, Gong S, Myriam H, Schaefer A, Doyle J, Stevens T, Dougherty J, Greengard P. Molecular definition of CNS cell types and their physiologic responses in health and disease. The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a201-c  0.688
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/J.Neuron.2006.07.025  0.766
2006 Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011  0.49
2005 Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy. 1: 11-22. PMID 16874045 DOI: 10.4161/Auto.1.1.1513  0.304
2005 Selimi F, Heintz N. How neurons keep in touch. Nature Neuroscience. 8: 1417-8. PMID 16251974 DOI: 10.1038/nn1105-1417  0.341
2005 Hatten ME, Heintz N. Large-scale genomic approaches to brain development and circuitry. Annual Review of Neuroscience. 28: 89-108. PMID 16022591 DOI: 10.1146/annurev.neuro.26.041002.131436  0.341
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/J.Neuron.2005.03.025  0.558
2005 Anthony TE, Heintz N. Cre-ating somatic cell genetic mosaics in the mouse. Cell. 121: 322-3. PMID 15882615 DOI: 10.1016/J.Cell.2005.04.019  0.76
2005 Anthony TE, Mason HA, Gridley T, Fishell G, Heintz N. Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes & Development. 19: 1028-33. PMID 15879553 DOI: 10.1101/Gad.1302105  0.775
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/Ng0904-921  0.305
2004 Ibañez-Tallon I, Wen H, Miwa JM, Xing J, Tekinay AB, Ono F, Brehm P, Heintz N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron. 43: 305-11. PMID 15294139 DOI: 10.1016/J.Neuron.2004.07.015  0.772
2004 Ibañez-Tallon I, Pagenstecher A, Fliegauf M, Olbrich H, Kispert A, Ketelsen UP, North A, Heintz N, Omran H. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Human Molecular Genetics. 13: 2133-41. PMID 15269178 DOI: 10.1093/Hmg/Ddh219  0.31
2004 Heintz N. Gene expression nervous system atlas (GENSAT). Nature Neuroscience. 7: 483. PMID 15114362 DOI: 10.1038/nn0504-483  0.307
2004 Anthony TE, Klein C, Fishell G, Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 41: 881-90. PMID 15046721 DOI: 10.1016/S0896-6273(04)00140-0  0.764
2003 Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15077-82. PMID 14657337 DOI: 10.1073/Pnas.2436255100  0.305
2003 Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 425: 917-25. PMID 14586460 DOI: 10.1038/nature02033  0.372
2002 Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/Gr.476202  0.489
2002 Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N. A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron. 35: 921-33. PMID 12372286 DOI: 10.1016/S0896-6273(02)00861-9  0.337
2002 Ibañez-Tallon I, Gorokhova S, Heintz N. Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Human Molecular Genetics. 11: 715-21. PMID 11912187 DOI: 10.1093/Hmg/11.6.715  0.623
2002 Ibañez-Tallon I, Miwa JM, Wang HL, Adams NC, Crabtree GW, Sine SM, Heintz N. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron. 33: 893-903. PMID 11906696 DOI: 10.1016/S0896-6273(02)00632-3  0.721
2001 Heintz N. BAC to the future: the use of bac transgenic mice for neuroscience research. Nature Reviews. Neuroscience. 2: 861-70. PMID 11733793 DOI: 10.1038/35104049  0.319
2001 Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5  0.469
2000 Heintz N. One-hit neuronal death. Nature. 406: 137, 139. PMID 10910338 DOI: 10.1038/35018196  0.322
2000 Heintz N, Zoghbi HY. Insights from mouse models into the molecular basis of neurodegeneration. Annual Review of Physiology. 62: 779-802. PMID 10845111 DOI: 10.1146/annurev.physiol.62.1.779  0.335
2000 Doughty ML, De Jager PL, Korsmeyer SJ, Heintz N. Neurodegeneration in Lurcher mice occurs via multiple cell death pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3687-94. PMID 10804210 DOI: 10.1523/Jneurosci.20-10-03687.2000  0.337
2000 Heintz N. Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis. Human Molecular Genetics. 9: 937-43. PMID 10767317 DOI: 10.1093/Hmg/9.6.937  0.39
1999 Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896  0.54
1999 Heintz N, De Jager PL. GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice. Annals of the New York Academy of Sciences. 868: 502-14. PMID 10414327 DOI: 10.1111/j.1749-6632.1999.tb11319.x  0.402
1999 Miwa JM, Ibanez-Tallon I, Crabtree GW, Sánchez R, Sali A, Role LW, Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron. 23: 105-14. PMID 10402197 DOI: 10.1016/S0896-6273(00)80757-6  0.805
1998 De Jager PL, Heintz N. The lurcher mutation and ionotropic glutamate receptors: contributions to programmed neuronal death in vivo. Brain Pathology (Zurich, Switzerland). 8: 795-807. PMID 9804384 DOI: 10.1111/J.1750-3639.1998.Tb00201.X  0.374
1998 Gubbay J, Doyle JP, Skinner M, Heintz N. Changing patterns of gene expression identify multiple steps during regression of rat prostate in vivo. Endocrinology. 139: 2935-43. PMID 9607804 DOI: 10.1210/Endo.139.6.6075  0.306
1997 Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/Nbt0997-859  0.491
1997 Rousselot P, Heintz N, Nottebohm F. Expression of brain lipid binding protein in the brain of the adult canary and its implications for adult neurogenesis. The Journal of Comparative Neurology. 385: 415-26. PMID 9300768 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<415::AID-CNE6>3.0.CO;2-6  0.31
1997 Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388: 769-73. PMID 9285588 DOI: 10.1038/42009  0.385
1997 Arnold DB, Heintz N. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 8842-7. PMID 9238065 DOI: 10.1073/pnas.94.16.8842  0.344
1997 Cheng SS, Heintz N. Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2400-7. PMID 9065501 DOI: 10.1523/Jneurosci.17-07-02400.1997  0.375
1997 Hatten ME, Alder J, Zimmerman K, Heintz N. Genes involved in cerebellar cell specification and differentiation. Current Opinion in Neurobiology. 7: 40-7. PMID 9039803 DOI: 10.1016/S0959-4388(97)80118-3  0.369
1996 Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192 DOI: 10.1101/Gad.10.19.2389  0.612
1996 Heintz N. Ataxia telangiectasia: cell signaling, cell death and the cell cycle. Current Opinion in Neurology. 9: 137-40. PMID 8782982 DOI: 10.1097/00019052-199604000-00014  0.333
1996 Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807  0.517
1996 Zheng C, Heintz N, Hatten ME. CNS gene encoding astrotactin, which supports neuronal migration along glial fibers. Science (New York, N.Y.). 272: 417-9. PMID 8602532 DOI: 10.1126/Science.272.5260.417  0.385
1995 Zuo J, De Jager PL, Norman DJ, Heintz N. Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6. Genome Research. 5: 381-92. PMID 8750197 DOI: 10.1101/Gr.5.4.381  0.315
1995 Hatten ME, Heintz N. Mechanisms of neural patterning and specification in the developing cerebellum. Annual Review of Neuroscience. 18: 385-408. PMID 7605067 DOI: 10.1146/annurev.ne.18.030195.002125  0.389
1995 Feng L, Heintz N. Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development (Cambridge, England). 121: 1719-30. PMID 7600988  0.312
1994 Feng L, Hatten ME, Heintz N. Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron. 12: 895-908. PMID 8161459 DOI: 10.1016/0896-6273(94)90341-7  0.38
1994 Martinelli R, Heintz N. H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. Molecular and Cellular Biology. 14: 8322-32. PMID 7969168 DOI: 10.1128/Mcb.14.12.8322  0.327
1994 Arnold D, Feng L, Kim J, Heintz N. A strategy for the analysis of gene expression during neural development. Proceedings of the National Academy of Sciences of the United States of America. 91: 9970-4. PMID 7937928 DOI: 10.1073/pnas.91.21.9970  0.597
1994 Baird DH, Hatten ME, Heintz N, Mason CA. Micromethods for Analyzing Axon-Target Interactions in Vitro Neuroprotocols. 4: 106-115. DOI: 10.1006/ncmn.1994.1013  0.307
1993 McKinney JD, Chang F, Heintz N, Cross FR. Negative regulation of FAR1 at the Start of the yeast cell cycle. Genes & Development. 7: 833-43. PMID 8491380 DOI: 10.1101/Gad.7.5.833  0.326
1991 Fletcher C, Norman DJ, Heintz N. Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics. 9: 647-55. PMID 2037292 DOI: 10.1016/0888-7543(91)90358-L  0.303
1991 Gao WO, Heintz N, Hatten ME. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron. 6: 705-15. PMID 2025426 DOI: 10.1016/0896-6273(91)90168-Y  0.379
1991 Heintz N. The regulation of histone gene expression during the cell cycle. Biochimica Et Biophysica Acta. 1088: 327-39. PMID 2015297 DOI: 10.1016/0167-4781(91)90122-3  0.318
1991 La Bella F, Heintz N. Histone gene transcription factor binding in extracts of normal human cells. Molecular and Cellular Biology. 11: 5825-31. PMID 1944265 DOI: 10.1128/Mcb.11.12.5825  0.341
1991 Roberts SB, Segil N, Heintz N. Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science (New York, N.Y.). 253: 1022-6. PMID 1887216 DOI: 10.1126/Science.1887216  0.329
1991 McKinney JD, Heintz N. Transcriptional regulation in the eukaryotic cell cycle. Trends in Biochemical Sciences. 16: 430-5. PMID 1776174 DOI: 10.1016/0968-0004(91)90170-Z  0.324
1991 Segil N, Roberts SB, Heintz N. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science (New York, N.Y.). 254: 1814-6. PMID 1684878 DOI: 10.1126/Science.1684878  0.315
1990 Ross ME, Fletcher C, Mason CA, Hatten ME, Heintz N. Meander tail reveals a discrete developmental unit in the mouse cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 87: 4189-92. PMID 2349228 DOI: 10.1073/pnas.87.11.4189  0.353
1989 Gallinari P, La Bella F, Heintz N. Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element. Molecular and Cellular Biology. 9: 1566-75. PMID 2725515 DOI: 10.1128/Mcb.9.4.1566  0.317
1989 La Bella F, Gallinari P, McKinney J, Heintz N. Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro. Genes & Development. 3: 1982-90. PMID 2620829 DOI: 10.1101/Gad.3.12A.1982  0.321
1988 O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485 DOI: 10.1126/Science.3413485  0.441
1988 LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460 DOI: 10.1101/Gad.2.1.32  0.661
1988 Dailey L, Roberts SB, Heintz N. Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2. Genes & Development. 2: 1700-12. PMID 3071490 DOI: 10.1101/Gad.2.12B.1700  0.333
1987 Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0  0.478
1987 Simon MC, Kitchener K, Kao HT, Hickey E, Weber L, Voellmy R, Heintz N, Nevins JR. Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Molecular and Cellular Biology. 7: 2884-90. PMID 2959854 DOI: 10.1128/Mcb.7.8.2884  0.318
1986 Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962 DOI: 10.1073/Pnas.83.19.7241  0.471
1986 Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588 DOI: 10.1128/mcb.6.10.3329-3340.1986  0.653
1985 Kao HT, Capasso O, Heintz N, Nevins JR. Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Molecular and Cellular Biology. 5: 628-33. PMID 3872994 DOI: 10.1128/MCB.5.4.628  0.341
1985 Capasso O, Heintz N. Regulated expression of mammalian histone H4 genes in vivo requires a trans-acting transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 82: 5622-6. PMID 3862085 DOI: 10.1073/Pnas.82.17.5622  0.349
1984 Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823  0.416
1984 Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888 DOI: 10.1128/mcb.4.12.2723-2734.1984  0.659
1983 Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409  0.473
1983 Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359 DOI: 10.1073/PNAS.80.15.4770  0.335
1983 Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835 DOI: 10.1128/mcb.3.4.539-550.1983  0.638
1981 Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1  0.456
1981 Roeder RG, Heintz N, Honda B, Lee D, Luse D, Matsui T, Segall J, Shastry B. Initiation of Eukaryotic Gene Transcription in Vitro Biochemical Society Transactions. 9: 120P-120P. DOI: 10.1042/bst009120p  0.393
1980 Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7  0.367
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