Karen S. Wilcox - Publications

University of Utah, Salt Lake City, UT 
basic mechanisms of epilepsy, anticonvulsant drug development

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Batot G, Metcalf CS, Bell LA, Pauletti A, Wilcox KS, Bröer S. A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus. Journal of Visualized Experiments : Jove. PMID 35816000 DOI: 10.3791/63673  0.37
2021 West PJ, Thomson K, Billingsley P, Pruess T, Rueda C, Saunders GW, Smith MD, Metcalf CS, Wilcox KS. Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs. Experimental Neurology. 349: 113954. PMID 34922908 DOI: 10.1016/j.expneurol.2021.113954  0.36
2021 Barker-Haliski M, Knox K, Zierath D, Koneval Z, Metcalf C, Wilcox KS, White HS. Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital. Epilepsia. PMID 34080183 DOI: 10.1111/epi.16955  0.535
2021 Galanopoulou AS, Löscher W, Lubbers L, O'Brien TJ, Staley K, Vezzani A, D'Ambrosio R, White HS, Sontheimer H, Wolf JA, Twyman R, Whittemore V, Wilcox KS, Klein B. Antiepileptogenesis and disease modification: Progress, challenges, and the path forward-Report of the Preclinical Working Group of the 2018 NINDS-sponsored antiepileptogenesis and disease modification workshop. Epilepsia Open. PMID 34033232 DOI: 10.1002/epi4.12490  0.474
2021 Pernici CD, Mensah JA, Dahle EJ, Johnson KJ, Handy L, Buxton L, Smith MD, West PJ, Metcalf CS, Wilcox KS. Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program. Epilepsia. PMID 34002394 DOI: 10.1111/epi.16925  0.331
2021 Thomson KE, West PJ, Metcalf CS, Wilcox KS. Response: Usefulness of the post-kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects. Epilepsia. PMID 33778946 DOI: 10.1111/epi.16884  0.311
2020 Fumeaux NF, Ebrahim S, Coughlin BF, Kadambi A, Azmi A, Xu JX, Abou Jaoude M, Nagaraj SB, Thomson KE, Newell TG, Metcalf CS, Wilcox KS, Kimchi EY, Moraes MFD, Cash SS. Accurate detection of spontaneous seizures using a generalized linear model with external validation. Epilepsia. PMID 32761902 DOI: 10.1111/Epi.16628  0.443
2020 Thomson KE, Metcalf CS, Newell TG, Huff J, Edwards SF, West PJ, Wilcox KS. Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats. Epilepsia. PMID 32420627 DOI: 10.1111/Epi.16531  0.436
2020 Li X, Himes RA, Prosser LC, Christie CF, Watt E, Edwards SF, Metcalf C, West P, Wilcox K, Chan SSL, Chou CJ. Discovery of the first Vitamin K analog as a potential treatment of pharmacoresistant seizures. Journal of Medicinal Chemistry. PMID 32390424 DOI: 10.1021/acs.jmedchem.0c00168  0.454
2020 Clarkson C, Smeal RM, Hasenoehrl MG, White JA, Rubio ME, Wilcox KS. Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy. Experimental Neurology. 113196. PMID 31935368 DOI: 10.1016/J.Expneurol.2020.113196  0.755
2019 Wilcox KS, West PJ, Metcalf CS. The Current Approach of the Epilepsy Therapy Screening Program Contract Site for Identifying Improved Therapies for the Treatment of Pharmacoresistant Seizures in Epilepsy. Neuropharmacology. 107811. PMID 31790717 DOI: 10.1016/j.neuropharm.2019.107811  0.433
2019 Patel DC, Wallis G, Fujinami RS, Wilcox KS, Smith MD. Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus. Epilepsia Open. 4: 431-442. PMID 31440724 DOI: 10.1002/epi4.12351  0.306
2019 Isom LL, Wilcox KS, Brooks-Kayal A. Mechanisms of Epilepsy and Neuronal Synchronization Gordon Research Conference Power Hour Summary. Epilepsy Currents. 1535759719858342. PMID 31282199 DOI: 10.1177/1535759719858342  0.361
2019 Loewen JL, Albertini G, Dahle EJ, Sato H, Smolders IJ, Massie A, Wilcox KS. Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity. Experimental Neurology. PMID 31022385 DOI: 10.1016/j.expneurol.2019.04.010  0.495
2018 Umpierre AD, West PJ, White JA, Wilcox KS. Conditional Knockout of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30504280 DOI: 10.1523/JNEUROSCI.1148-18.2018  0.718
2018 West PJ, Saunders GW, Billingsley P, Smith MD, White HS, Metcalf CS, Wilcox KS. Recurrent epileptiform discharges in the medial entorhinal cortex of kainate-treated rats are differentially sensitive to antiseizure drugs. Epilepsia. PMID 30328622 DOI: 10.1111/epi.14563  0.644
2017 Patel DC, Wilcox KS, Metcalf CS. Novel Targets for Developing Antiseizure and, Potentially, Antiepileptogenic Drugs. Epilepsy Currents. 17: 293-298. PMID 29225544 DOI: 10.5698/1535-7597.17.5.293  0.449
2017 Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J, Morrison J, Nehlig A, Prasad A, Wilcox KS, et al. Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research? Epilepsy & Behavior : E&B. PMID 29097123 DOI: 10.1016/J.Yebeh.2017.09.016  0.363
2017 Remigio GJ, Loewen JL, Heuston S, Helgeson C, Steve White H, Wilcox KS, West PJ. Corneal kindled C57BL/6 mice exhibit saturated dentate gyrus long-term potentiation and associated memory deficits in the absence of overt neuron loss. Neurobiology of Disease. PMID 28624414 DOI: 10.1016/J.Nbd.2017.06.006  0.439
2017 Patel DC, Wallis G, Dahle EJ, McElroy PB, Thomson KE, Tesi RJ, Szymkowski DE, West PJ, Smeal RM, Patel M, Fujinami RS, White HS, Wilcox KS. Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy. Eneuro. 4. PMID 28497109 DOI: 10.1523/ENEURO.0105-17.2017  0.607
2017 Klein BD, Jacobson CA, Metcalf CS, Smith MD, Wilcox KS, Hampson AJ, Kehne JH. Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP). Neurochemical Research. PMID 28478594 DOI: 10.1007/S11064-017-2287-8  0.486
2017 Metcalf CS, West PJ, Thomson KE, Edwards SF, Smith MD, White HS, Wilcox KS. Development and pharmacologic characterization of the rat 6 Hz model of partial seizures. Epilepsia. PMID 28449218 DOI: 10.1111/Epi.13764  0.626
2017 Barker-Haliski ML, Johnson K, Billingsley P, Huff J, Handy LJ, Khaleel R, Lu Z, Mau MJ, Pruess TH, Rueda C, Saunders G, Underwood TK, Vanegas F, Smith MD, West PJ, ... Wilcox KS, et al. Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy. Neurochemical Research. PMID 28303498 DOI: 10.1007/s11064-017-2227-7  0.474
2016 Barker-Haliski ML, Heck TD, Dahle EJ, Vanegas F, Pruess TH, Wilcox KS, White HS. Acute treatment with minocycline, but not valproic acid, improves long-term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy. Epilepsia. PMID 27739576 DOI: 10.1111/Epi.13577  0.571
2016 Meisler MH, Helman G, Hammer MF, Fureman BE, Gaillard WD, Goldin AL, Hirose S, Ishii A, Kroner BL, Lossin C, Mefford HC, Parent JM, Patel M, Schreiber J, Stewart R, ... ... Wilcox K, et al. SCN8A encephalopathy: Research progress and prospects. Epilepsia. PMID 27270488 DOI: 10.1111/Epi.13422  0.304
2016 Libbey JE, Hanak TJ, Doty DJ, Wilcox KS, Fujinami RS. NBQX, a highly selective competitive antagonist of AMPA and KA ionotropic glutamate receptors, increases seizures and mortality following picornavirus infection. Experimental Neurology. PMID 27072529 DOI: 10.1016/J.Expneurol.2016.04.010  0.522
2016 Loewen JL, Barker-Haliski ML, Dahle EJ, White HS, Wilcox KS. Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy. Journal of Neuropathology and Experimental Neurology. PMID 26945036 DOI: 10.1093/Jnen/Nlw008  0.611
2016 Umpierre AD, Bennett IV, Nebeker LD, Newell TG, Tian BB, Thomson KE, White HS, White JA, Wilcox KS. Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures. Experimental Neurology. PMID 26896834 DOI: 10.1016/J.Expneurol.2016.02.014  0.773
2015 Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC. sec-Butylpropylacetamide (SPD) has antimigraine properties. Cephalalgia : An International Journal of Headache. PMID 26568161 DOI: 10.1177/0333102415612773  0.547
2015 Smeal RM, Fujinami R, White HS, Wilcox KS. Decrease in CA3 inhibitory network activity during Theiler's virus encephalitis. Neuroscience Letters. 609: 210-215. PMID 26477780 DOI: 10.1016/J.Neulet.2015.10.032  0.629
2015 Wilcox KS, Gee JM, Gibbons MB, Tvrdik P, White JA. Altered structure and function of astrocytes following status epilepticus. Epilepsy & Behavior : E&B. 49: 17-9. PMID 26219575 DOI: 10.1016/J.Yebeh.2015.05.002  0.825
2015 Bhuyan P, Patel DC, Wilcox KS, Patel M. Oxidative stress in murine Theiler's virus-induced temporal lobe epilepsy. Experimental Neurology. 271: 329-334. PMID 26079647 DOI: 10.1016/j.expneurol.2015.06.012  0.475
2015 Gee JM, Gibbons MB, Taheri M, Palumbos S, Morris SC, Smeal RM, Flynn KF, Economo MN, Cizek CG, Capecchi MR, Tvrdik P, Wilcox KS, White JA. Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation. Frontiers in Molecular Neuroscience. 8: 10. PMID 25926768 DOI: 10.3389/Fnmol.2015.00010  0.788
2015 Barker-Haliski ML, Dahle EJ, Heck TD, Pruess TH, Vanegas F, Wilcox KS, White HS. Evaluating an etiologically relevant platform for therapy development for temporal lobe epilepsy: effects of carbamazepine and valproic acid on acute seizures and chronic behavioral comorbidities in the Theiler's murine encephalomyelitis virus mouse model. The Journal of Pharmacology and Experimental Therapeutics. 353: 318-29. PMID 25755209 DOI: 10.1124/Jpet.114.222513  0.618
2015 Wilcox KS, Gee JM, Gibbons MB, Tvrdik P, White JA. Altered structure and function of astrocytes following status epilepticus Epilepsy and Behavior. 49: 17-19. DOI: 10.1016/j.yebeh.2015.05.002  0.768
2014 Gibbons MB, Wilcox KS. Could Astrocytes Be Used to Beat Epilepsy? Experiments in dnSNARE Mice Drum Up New Hope. Epilepsy Currents / American Epilepsy Society. 14: 277-8. PMID 25346638 DOI: 10.5698/1535-7597-14.5.277  0.402
2014 Gee JM, Smith NA, Fernandez FR, Economo MN, Brunert D, Rothermel M, Morris SC, Talbot A, Palumbos S, Ichida JM, Shepherd JD, West PJ, Wachowiak M, Capecchi MR, Wilcox KS, et al. Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse. Neuron. 83: 1058-72. PMID 25155958 DOI: 10.1016/J.Neuron.2014.07.024  0.77
2014 Simonato M, Brooks-Kayal AR, Engel J, Galanopoulou AS, Jensen FE, Moshé SL, O'Brien TJ, Pitkanen A, Wilcox KS, French JA. The challenge and promise of anti-epileptic therapy development in animal models. The Lancet. Neurology. 13: 949-60. PMID 25127174 DOI: 10.1016/S1474-4422(14)70076-6  0.425
2014 Wilcox KS, Vezzani A. Does brain inflammation mediate pathological outcomes in epilepsy? Advances in Experimental Medicine and Biology. 813: 169-83. PMID 25012376 DOI: 10.1007/978-94-017-8914-1_14  0.501
2014 West PJ, Saunders GW, Remigio GJ, Wilcox KS, White HS. Antiseizure drugs differentially modulate θ-burst induced long-term potentiation in C57BL/6 mice. Epilepsia. 55: 214-23. PMID 24447124 DOI: 10.1111/Epi.12524  0.553
2014 Umpierre AD, Remigio GJ, Dahle EJ, Bradford K, Alex AB, Smith MD, West PJ, White HS, Wilcox KS. Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler's virus model of temporal lobe epilepsy. Neurobiology of Disease. 64: 98-106. PMID 24412221 DOI: 10.1016/J.Nbd.2013.12.015  0.604
2014 Cusick M, Libbey J, Patel D, Wilcox K, Fujinami R. Acute seizures during viral encephalitis are due to IL-6-producing macrophages Journal of Neuroimmunology. 275: 98-99. DOI: 10.1016/J.Jneuroim.2014.08.264  0.36
2013 McComsey DF, Smith-Swintosky VL, Parker MH, Brenneman DE, Malatynska E, White HS, Klein BD, Wilcox KS, Milewski ME, Herb M, Finley MF, Liu Y, Lubin ML, Qin N, Reitz AB, et al. Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112). Journal of Medicinal Chemistry. 56: 9019-30. PMID 24205976 DOI: 10.1021/Jm400894U  0.598
2013 Vargas JR, Takahashi DK, Thomson KE, Wilcox KS. The expression of kainate receptor subunits in hippocampal astrocytes after experimentally induced status epilepticus. Journal of Neuropathology and Experimental Neurology. 72: 919-32. PMID 24042195 DOI: 10.1097/Nen.0B013E3182A4B266  0.815
2013 Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. Issues related to development of new antiseizure treatments. Epilepsia. 54: 24-34. PMID 23909851 DOI: 10.1111/Epi.12296  0.711
2013 Srivastava AK, Alex AB, Wilcox KS, White HS. Rapid loss of efficacy to the antiseizure drugs lamotrigine and carbamazepine: a novel experimental model of pharmacoresistant epilepsy. Epilepsia. 54: 1186-94. PMID 23750799 DOI: 10.1111/Epi.12234  0.64
2013 Gibbons MB, Smeal RM, Takahashi DK, Vargas JR, Wilcox KS. Contributions of astrocytes to epileptogenesis following status epilepticus: opportunities for preventive therapy? Neurochemistry International. 63: 660-9. PMID 23266599 DOI: 10.1016/j.neuint.2012.12.008  0.815
2012 Smeal RM, Stewart KA, Iacob E, Fujinami RS, White HS, Wilcox KS. The activity within the CA3 excitatory network during Theiler's virus encephalitis is distinct from that observed during chronic epilepsy. Journal of Neurovirology. 18: 30-44. PMID 22328242 DOI: 10.1007/S13365-012-0082-5  0.603
2012 White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia. 53: 134-46. PMID 22150444 DOI: 10.1111/J.1528-1167.2011.03338.X  0.622
2011 Libbey JE, Kennett NJ, Wilcox KS, White HS, Fujinami RS. Once initiated, viral encephalitis-induced seizures are consistent no matter the treatment or lack of interleukin-6. Journal of Neurovirology. 17: 496-9. PMID 21833798 DOI: 10.1007/S13365-011-0050-5  0.589
2011 Libbey JE, Kennett NJ, Wilcox KS, White HS, Fujinami RS. Lack of correlation of central nervous system inflammation and neuropathology with the development of seizures following acute virus infection. Journal of Virology. 85: 8149-57. PMID 21680509 DOI: 10.1128/Jvi.00730-11  0.596
2011 Simeone TA, Wilcox KS, White HS. cAMP-dependent protein kinase A activity modulates topiramate potentiation of GABA(A) receptors. Epilepsy Research. 96: 176-9. PMID 21665439 DOI: 10.1016/J.Eplepsyres.2011.05.009  0.743
2011 Libbey JE, Kennett NJ, Wilcox KS, White HS, Fujinami RS. Interleukin-6, produced by resident cells of the central nervous system and infiltrating cells, contributes to the development of seizures following viral infection. Journal of Virology. 85: 6913-22. PMID 21543484 DOI: 10.1128/Jvi.00458-11  0.596
2011 Simeone TA, Wilcox KS, White HS. Topiramate modulation of β(1)- and β(3)-homomeric GABA(A) receptors. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 44-52. PMID 21421049 DOI: 10.1016/J.Phrs.2011.03.004  0.752
2011 Alex AB, Saunders GW, Dalpé-Charron A, Reilly CA, Wilcox KS. CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors. Neurotoxicology. 32: 392-9. PMID 21396956 DOI: 10.1016/j.neuro.2011.03.002  0.352
2010 Stewart KA, Wilcox KS, Fujinami RS, White HS. Development of postinfection epilepsy after Theiler's virus infection of C57BL/6 mice. Journal of Neuropathology and Experimental Neurology. 69: 1210-9. PMID 21107134 DOI: 10.1097/Nen.0B013E3181Ffc420  0.611
2010 Takahashi DK, Vargas JR, Wilcox KS. Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus. Neurobiology of Disease. 40: 573-85. PMID 20691786 DOI: 10.1016/j.nbd.2010.07.018  0.816
2010 Libbey JE, Kirkman NJ, Wilcox KS, White HS, Fujinami RS. Role for complement in the development of seizures following acute viral infection. Journal of Virology. 84: 6452-60. PMID 20427530 DOI: 10.1128/Jvi.00422-10  0.598
2010 Stewart KA, Wilcox KS, Fujinami RS, White HS. Theiler's virus infection chronically alters seizure susceptibility. Epilepsia. 51: 1418-28. PMID 20002148 DOI: 10.1111/J.1528-1167.2009.02405.X  0.617
2010 Kirkman NJ, Libbey JE, Wilcox KS, White HS, Fujinami RS. Innate but not adaptive immune responses contribute to behavioral seizures following viral infection. Epilepsia. 51: 454-64. PMID 19845729 DOI: 10.1111/J.1528-1167.2009.02390.X  0.589
2010 Brenner R, Wilcox KS. Potassium channelopathies of epilepsy Epilepsia. 51: 60. DOI: 10.1111/J.1528-1167.2010.02846.X  0.42
2009 Otto JF, Singh NA, Dahle EJ, Leppert MF, Pappas CM, Pruess TH, Wilcox KS, White HS. Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions. Epilepsia. 50: 1752-9. PMID 19453707 DOI: 10.1111/J.1528-1167.2009.02100.X  0.803
2009 Singh NA, Otto JF, Leppert MF, White HS, Wilcox KS. Mouse models of benign familial neonatal convulsions (BFNC): Mutations in KCNQ (Kv7) genes Neuromethods. 40: 107-120. DOI: 10.1007/978-1-60327-263-6_7  0.718
2008 Smeal RM, Keefe KA, Wilcox KS. Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum. The European Journal of Neuroscience. 28: 2041-52. PMID 19046385 DOI: 10.1111/J.1460-9568.2008.06505.X  0.358
2008 Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. The Journal of Physiology. 586: 3405-23. PMID 18483067 DOI: 10.1113/Jphysiol.2008.154971  0.82
2008 Foreman MM, Hanania T, Stratton SC, Wilcox KS, White HS, Stables JP, Eller M. In vivo pharmacological effects of JZP-4, a novel anticonvulsant, in models for anticonvulsant, antimania and antidepressant activity. Pharmacology, Biochemistry, and Behavior. 89: 523-34. PMID 18377968 DOI: 10.1016/J.Pbb.2008.02.007  0.58
2008 Libbey JE, Kirkman NJ, Smith MC, Tanaka T, Wilcox KS, White HS, Fujinami RS. Seizures following picornavirus infection. Epilepsia. 49: 1066-74. PMID 18325012 DOI: 10.1111/J.1528-1167.2008.01535.X  0.615
2008 Smith MD, Saunders GW, Clausen RP, Frølund B, Krogsgaard-Larsen P, Larsson OM, Schousboe A, Wilcox KS, White HS. Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC). Epilepsy Research. 79: 6-13. PMID 18262393 DOI: 10.1016/J.Eplepsyres.2007.12.009  0.542
2007 White HS, Smith MD, Wilcox KS. Mechanisms of action of antiepileptic drugs. International Review of Neurobiology. 81: 85-110. PMID 17433919 DOI: 10.1016/S0074-7742(06)81006-8  0.565
2007 Smith MD, Adams AC, Saunders GW, White HS, Wilcox KS. Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro. Epilepsy Research. 74: 97-106. PMID 17395429 DOI: 10.1016/J.Eplepsyres.2007.02.001  0.614
2007 West PJ, Dalpé-Charron A, Wilcox KS. Differential contribution of kainate receptors to excitatory postsynaptic currents in superficial layer neurons of the rat medial entorhinal cortex. Neuroscience. 146: 1000-12. PMID 17395391 DOI: 10.1016/j.neuroscience.2007.02.035  0.376
2007 Smith M, Wilcox KS, White HS. Discovery of antiepileptic drugs. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 4: 12-7. PMID 17199014 DOI: 10.1016/J.Nurt.2006.11.009  0.57
2007 Smeal RM, Gaspar RC, Keefe KA, Wilcox KS. A rat brain slice preparation for characterizing both thalamostriatal and corticostriatal afferents. Journal of Neuroscience Methods. 159: 224-35. PMID 16899300 DOI: 10.1016/J.Jneumeth.2006.07.007  0.35
2006 Simeone TA, Otto JF, Wilcox KS, White HS. Felbamate is a subunit selective modulator of recombinant gamma-aminobutyric acid type A receptors expressed in Xenopus oocytes. European Journal of Pharmacology. 552: 31-5. PMID 17056029 DOI: 10.1016/J.Ejphar.2006.09.002  0.769
2006 Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology. 51: 933-46. PMID 16890251 DOI: 10.1016/J.Neuropharm.2006.06.006  0.4
2006 Alex AB, Baucum AJ, Wilcox KS. Effect of Conantokin G on NMDA receptor-mediated spontaneous EPSCs in cultured cortical neurons. Journal of Neurophysiology. 96: 1084-92. PMID 16760339 DOI: 10.1152/Jn.01325.2005  0.345
2006 Simeone TA, Wilcox KS, White HS. Subunit selectivity of topiramate modulation of heteromeric GABA(A) receptors. Neuropharmacology. 50: 845-57. PMID 16490221 DOI: 10.1016/J.Neuropharm.2005.12.006  0.748
2006 Otto JF, Yang Y, Frankel WN, White HS, Wilcox KS. A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2053-9. PMID 16481438 DOI: 10.1523/Jneurosci.1575-05.2006  0.787
2006 White HS, Smith-Yockman M, Srivastava A, Wilcox KS. Therapeutic Assays for the Identification and Characterization of Antiepileptic and Antiepileptogenic Drugs Models of Seizures and Epilepsy. 539-549. DOI: 10.1016/B978-012088554-1/50046-3  0.413
2004 Otto JF, Yang Y, Frankel WN, Wilcox KS, White HS. Mice carrying the szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the m-channel. Epilepsia. 45: 1009-16. PMID 15329063 DOI: 10.1111/J.0013-9580.2004.65703.X  0.798
2004 Barton ME, White HS, Wilcox KS. The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs. Epilepsy Research. 59: 13-24. PMID 15135163 DOI: 10.1016/J.Eplepsyres.2003.12.011  0.56
2003 Kaplan MP, Wilcox KS, Dichter MA. Differences in multiple forms of short-term plasticity between excitatory and inhibitory hippocampal neurons in culture. Synapse (New York, N.Y.). 50: 41-52. PMID 12872293 DOI: 10.1002/Syn.10244  0.747
2003 Aaron GB, Wilcox KS, Dichter MA. Different patterns of synaptic transmission revealed between hippocampal CA3 stratum oriens and stratum lucidum interneurons and their pyramidal cell targets. Neuroscience. 117: 169-81. PMID 12605903 DOI: 10.1016/S0306-4522(02)00832-1  0.759
2003 Isoherranen N, Yagen B, Woodhead JH, Spiegelstein O, Blotnik S, Wilcox KS, Finnell RH, Bennett GD, White HS, Bialer M. Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. British Journal of Pharmacology. 138: 602-13. PMID 12598414 DOI: 10.1038/Sj.Bjp.0705076  0.6
2003 Chapman DE, Keefe KA, Wilcox KS. Evidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatum. Journal of Neurophysiology. 89: 69-80. PMID 12522160 DOI: 10.1152/Jn.00342.2002  0.405
2002 Isoherranen N, White HS, Finnell RH, Yagen B, Woodhead JH, Bennett GD, Wilcox KS, Barton ME, Bialer M. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug. Epilepsia. 43: 115-26. PMID 11903457 DOI: 10.1046/J.1528-1157.2002.25801.X  0.611
2002 Otto JF, Kimball MM, Wilcox KS. Effects of the anticonvulsant retigabine on cultured cortical neurons: changes in electroresponsive properties and synaptic transmission. Molecular Pharmacology. 61: 921-7. PMID 11901232 DOI: 10.1124/Mol.61.4.921  0.757
1998 Kendrick SJ, Dichter MA, Wilcox KS. Characterization of desensitization in recombinant N-methyl-D-aspartate receptors: comparison with native receptors in cultured hippocampal neurons. Brain Research. Molecular Brain Research. 57: 10-20. PMID 9630479 DOI: 10.1016/S0169-328X(98)00054-0  0.599
1998 Lee JE, Wilcox K, Jacobson KA, Dichter M, Liang BT. Adenosine receptor subtypes and cardioprotection Drug Development Research. 45: 394-401. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<394::Aid-Ddr40>3.0.Co;2-J  0.554
1996 Wilcox KS, Fitzsimonds RM, Johnson B, Dichter MA. Glycine regulation of synaptic NMDA receptors in hippocampal neurons. Journal of Neurophysiology. 76: 3415-24. PMID 8930282 DOI: 10.1152/Jn.1996.76.5.3415  0.785
1996 Cao Y, Wilcox KS, Martin CE, Rachinsky TL, Eberwine J, Dichter MA. Presence of mRNA for glutamic acid decarboxylase in both excitatory and inhibitory neurons. Proceedings of the National Academy of Sciences of the United States of America. 93: 9844-9. PMID 8790419 DOI: 10.1073/Pnas.93.18.9844  0.599
1996 Cummings DD, Wilcox KS, Dichter MA. Calcium-dependent paired-pulse facilitation of miniature EPSC frequency accompanies depression of EPSCs at hippocampal synapses in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5312-23. PMID 8757244 DOI: 10.1523/Jneurosci.16-17-05312.1996  0.578
1994 Wilcox KS, Dichter MA. Paired pulse depression in cultured hippocampal neurons is due to a presynaptic mechanism independent of GABAB autoreceptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1775-88. PMID 8126570 DOI: 10.1523/Jneurosci.14-03-01775.1994  0.622
1994 Wilcox KS, Buchhalter J, Dichter MA. Properties of inhibitory and excitatory synapses between hippocampal neurons in very low density cultures. Synapse (New York, N.Y.). 18: 128-51. PMID 7839312 DOI: 10.1002/Syn.890180206  0.632
1989 Wilcox KS, Grant SJ, Burkhart BA, Christoph GR. In vitro electrophysiology of neurons in the lateral dorsal tegmental nucleus. Brain Research Bulletin. 22: 557-60. PMID 2713729 DOI: 10.1016/0361-9230(89)90111-1  0.311
1988 Wilcox KS, Gutnick MJ, Christoph GR. Electrophysiological properties of neurons in the lateral habenula nucleus: an in vitro study. Journal of Neurophysiology. 59: 212-25. PMID 3343602 DOI: 10.1152/Jn.1988.59.1.212  0.319
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