John Orlowski - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Animal Physiology Biology, Neuroscience Biology, Pharmacology

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Freeman SA, Grinstein S, Orlowski J. Determinants, Maintenance and Function of Organellar pH. Physiological Reviews. PMID 35981302 DOI: 10.1152/physrev.00009.2022  0.311
2022 Dong Y, Li H, Ilie A, Gao Y, Boucher A, Zhang XC, Orlowski J, Zhao Y. Structural basis of autoinhibition of the human NHE3-CHP1 complex. Science Advances. 8: eabn3925. PMID 35613257 DOI: 10.1126/sciadv.abn3925  0.308
2021 Dong Y, Gao Y, Ilie A, Kim D, Boucher A, Li B, Zhang XC, Orlowski J, Zhao Y. Structure and mechanism of the human NHE1-CHP1 complex. Nature Communications. 12: 3474. PMID 34108458 DOI: 10.1038/s41467-021-23496-z  0.367
2020 Petitjean H, Fatima T, Mouchbahani-Constance S, Davidova A, Ferland CE, Orlowski J, Sharif-Naeini R. Loss of SLC9A6/NHE6 impairs nociception in a mouse model of Christianson Syndrome. Pain. PMID 32569089 DOI: 10.1097/J.Pain.0000000000001961  0.329
2020 Ilie A, Boucher A, Park J, Berghuis AM, McKinney RA, Orlowski J. Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome. The Journal of Biological Chemistry. PMID 32277048 DOI: 10.1074/Jbc.Ra120.012614  0.404
2019 Rajah A, Boudreau CG, Ilie A, Wee TL, Tang K, Borisov AZ, Orlowski J, Brown CM. Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX. Scientific Reports. 9: 11430. PMID 31391572 DOI: 10.1038/S41598-019-47722-3  0.378
2019 Gao AYL, Ilie A, Chang PKY, Orlowski J, McKinney RA. A Christianson syndrome-linked deletion mutation (Δ287ES288) in SLC9A6 impairs hippocampal neuronal plasticity. Neurobiology of Disease. 104490. PMID 31175985 DOI: 10.1016/J.Nbd.2019.104490  0.36
2018 Ilie A, Gao AYL, Boucher A, Park J, Berghuis AM, Hoffer MJV, Hilhorst-Hofstee Y, Anne McKinney R, Orlowski J. A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome. Neurobiology of Disease. PMID 30296617 DOI: 10.1016/j.nbd.2018.10.002  0.317
2017 Orlowski J. SMAD5 signaling: more than meets the nuclei. Cell Research. PMID 28809394 DOI: 10.1038/Cr.2017.101  0.315
2015 Jinadasa T, Josephson CB, Boucher A, Orlowski J. Determinants of Cation Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and Adjoining Exofacial Re-entrant Loop 5 of Na+/H+ Exchanger NHE1. The Journal of Biological Chemistry. 290: 18173-86. PMID 26063808 DOI: 10.1074/Jbc.M115.642199  0.766
2014 Jinadasa T, Szabó EZ, Numat M, Orlowski J. Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na(+)/H(+) exchanger NHE5 to the cell surface. The Journal of Biological Chemistry. 289: 20879-97. PMID 24936055 DOI: 10.1074/Jbc.M114.555284  0.743
2014 Ilie A, Weinstein E, Boucher A, McKinney RA, Orlowski J. Impaired posttranslational processing and trafficking of an endosomal Na+/H+ exchanger NHE6 mutant (Δ(370)WST(372)) associated with X-linked intellectual disability and autism. Neurochemistry International. 73: 192-203. PMID 24090639 DOI: 10.1016/J.Neuint.2013.09.020  0.484
2013 Hayashi H, Tamura A, Krishnan D, Tsukita S, Suzuki Y, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S, Alexander RT. Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3. Plos One. 8: e55623. PMID 23405179 DOI: 10.1371/Journal.Pone.0055623  0.476
2013 Deane EC, Ilie AE, Sizdahkhani S, Das Gupta M, Orlowski J, McKinney RA. Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 595-610. PMID 23303939 DOI: 10.1523/Jneurosci.2583-12.2013  0.424
2013 Lukashova V, Jinadasa T, Ilie A, Verbich D, Cooper E, Orlowski J. The Na(+)/H (+) exchanger NHE5 is sorted to discrete intracellular vesicles in the central and peripheral nervous systems. Advances in Experimental Medicine and Biology. 961: 397-410. PMID 23224898 DOI: 10.1007/978-1-4614-4756-6_34  0.778
2012 Zaun HC, Shrier A, Orlowski J. N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane. The Journal of Biological Chemistry. 287: 36883-95. PMID 22984264 DOI: 10.1074/Jbc.M112.394700  0.469
2012 Fonseca BD, Diering GH, Bidinosti MA, Dalal K, Alain T, Balgi AD, Forestieri R, Nodwell M, Rajadurai CV, Gunaratnam C, Tee AR, Duong F, Andersen RJ, Orlowski J, Numata M, et al. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. The Journal of Biological Chemistry. 287: 17530-45. PMID 22474287 DOI: 10.1074/Jbc.M112.359638  0.392
2011 Orlowski J, Grinstein S. Na+/H+ exchangers. Comprehensive Physiology. 1: 2083-100. PMID 23733698 DOI: 10.1002/Cphy.C110020  0.509
2011 Lukashova V, Szabó EZ, Jinadasa T, Mokhov A, Litchfield DW, Orlowski J. CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. The Journal of Biological Chemistry. 286: 11456-68. PMID 21296876 DOI: 10.1074/jbc.M110.182881  0.727
2011 Alexander RT, Jaumouillé V, Yeung T, Furuya W, Peltekova I, Boucher A, Zasloff M, Orlowski J, Grinstein S. Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. The Embo Journal. 30: 679-91. PMID 21245831 DOI: 10.1038/Emboj.2010.356  0.408
2010 Kintner DB, Chen X, Currie J, Chanana V, Ferrazzano P, Baba A, Matsuda T, Cohen M, Orlowski J, Chiu SY, Taunton J, Sun D. Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia. The Journal of Biological Chemistry. 285: 35155-68. PMID 20817726 DOI: 10.1074/Jbc.M110.101212  0.448
2010 Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG. BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction. The Journal of Biological Chemistry. 285: 8104-13. PMID 20080968 DOI: 10.1074/Jbc.M109.055079  0.522
2008 Zaun HC, Shrier A, Orlowski J. Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform. The Journal of Biological Chemistry. 283: 12456-67. PMID 18321853 DOI: 10.1074/Jbc.M800267200  0.494
2008 Hayashi H, Aharonovitz O, Alexander RT, Touret N, Furuya W, Orlowski J, Grinstein S. Na+/H+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis. American Journal of Physiology. Cell Physiology. 294: C526-34. PMID 18094149 DOI: 10.1152/Ajpcell.00219.2007  0.509
2007 Orlowski J, Grinstein S. Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Current Opinion in Cell Biology. 19: 483-92. PMID 17646094 DOI: 10.1016/J.Ceb.2007.06.001  0.432
2007 Alexander RT, Malevanets A, Durkan AM, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S. Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3. The Journal of Biological Chemistry. 282: 7376-84. PMID 17218318 DOI: 10.1074/Jbc.M608557200  0.433
2005 Alexander RT, Furuya W, Szászi K, Orlowski J, Grinstein S. Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proceedings of the National Academy of Sciences of the United States of America. 102: 12253-8. PMID 16103375 DOI: 10.1073/Pnas.0409197102  0.462
2005 Lin PJ, Williams WP, Luu Y, Molday RS, Orlowski J, Numata M. Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7. Journal of Cell Science. 118: 1885-97. PMID 15840657 DOI: 10.1242/Jcs.02315  0.476
2005 Szabó EZ, Numata M, Lukashova V, Iannuzzi P, Orlowski J. beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. Proceedings of the National Academy of Sciences of the United States of America. 102: 2790-5. PMID 15699339 DOI: 10.1073/Pnas.0407444102  0.776
2005 Kocinsky HS, Girardi AC, Biemesderfer D, Nguyen T, Mentone S, Orlowski J, Aronson PS. Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites. American Journal of Physiology. Renal Physiology. 289: F249-58. PMID 15687252 DOI: 10.1152/Ajprenal.00082.2004  0.435
2004 Hayashi H, Szászi K, Coady-Osberg N, Furuya W, Bretscher AP, Orlowski J, Grinstein S. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. The Journal of General Physiology. 123: 491-504. PMID 15078917 DOI: 10.1085/Jgp.200308979  0.49
2004 Orlowski J, Grinstein S. Diversity of the mammalian sodium/proton exchanger SLC9 gene family. PflüGers Archiv : European Journal of Physiology. 447: 549-65. PMID 12845533 DOI: 10.1007/S00424-003-1110-3  0.477
2002 Szaszi K, Paulsen A, Szabo EZ, Numata M, Grinstein S, Orlowski J. Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. The Journal of Biological Chemistry. 277: 42623-32. PMID 12205089 DOI: 10.1074/Jbc.M206629200  0.811
2002 Hayashi H, Szászi K, Coady-Osberg N, Orlowski J, Kinsella JL, Grinstein S. A slow pH-dependent conformational transition underlies a novel mode of activation of the epithelial Na+/H+ exchanger-3 isoform. The Journal of Biological Chemistry. 277: 11090-6. PMID 11792708 DOI: 10.1074/Jbc.M111868200  0.387
2001 Khadilkar A, Iannuzzi P, Orlowski J. Identification of Sites in the Second Exomembrane Loop and Ninth Transmembrane Helix of the Mammalian Na+/H+ Exchanger Important for Drug Recognition and Cation Translocation Journal of Biological Chemistry. 276: 43792-43800. PMID 11564737 DOI: 10.1074/Jbc.M106659200  0.346
2001 Szászi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J. Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. The Journal of Biological Chemistry. 276: 40761-8. PMID 11522794 DOI: 10.1074/Jbc.M106724200  0.515
2001 Aharonovitz O, Kapus A, Szászi K, Coady-Osberg N, Jancelewicz T, Orlowski J, Grinstein S. Modulation of Na+/H+ exchange activity by Cl- American Journal of Physiology - Cell Physiology. 281. PMID 11401835 DOI: 10.1152/Ajpcell.2001.281.1.C133  0.527
2001 Numata M, Orlowski J. Molecular Cloning and Characterization of a Novel (Na+,K +)/H+ Exchanger Localized to the trans-Golgi Network Journal of Biological Chemistry. 276: 17387-17394. PMID 11279194 DOI: 10.1074/Jbc.M101319200  0.507
2000 Denker SP, Huang DC, Orlowski J, Furthmayr H, Barber DL. Direct binding of the Na-H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H+ translocation Molecular Cell. 6: 1425-1436. PMID 11163215 DOI: 10.1016/S1097-2765(00)00139-8  0.407
2000 Szászi K, Grinstein S, Orlowski J, Kapus A. Regulation of the epithelial Na+/H+ exchanger isoform by the cytoskeleton Cellular Physiology and Biochemistry. 10: 265-272. PMID 11125205 DOI: 10.1159/000016358  0.549
2000 Aharonovitz O, Zaun HC, Balla T, York JD, Orlowski J, Grinstein S. Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. The Journal of Cell Biology. 150: 213-24. PMID 10893269 DOI: 10.1083/Jcb.150.1.213  0.547
2000 Szászi K, Kurashima K, Kapus A, Paulsen A, Kaibuchi K, Grinstein S, Orlowski J. RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation. The Journal of Biological Chemistry. 275: 28599-606. PMID 10893221 DOI: 10.1016/S1095-6433(00)80283-4  0.456
2000 Albrecht FE, Xu J, Moe OW, Hopfer U, Simonds WF, Orlowski J, Jose PA. Regulation of NHE3 activity by G protein subunits in renal brush-border membranes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R1064-73. PMID 10749796 DOI: 10.1152/Ajpregu.2000.278.4.R1064  0.341
2000 Szabó EZ, Numata M, Shull GE, Orlowski J. Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells. The Journal of Biological Chemistry. 275: 6302-7. PMID 10692428 DOI: 10.1074/Jbc.275.9.6302  0.808
1999 Chow CW, Khurana S, Woodside M, Grinstein S, Orlowski J. The epithelial Na(+)/H(+) exchanger, NHE3, is internalized through a clathrin-mediated pathway. The Journal of Biological Chemistry. 274: 37551-8. PMID 10608808 DOI: 10.1074/Jbc.274.53.37551  0.505
1999 Kurashia K, D'Souza S, Szászi K, Ramjeesingh R, Orlowski J, Grinstein S. The apical Na+/H+ exchanger isoform NHE3 is regulated by the actin cytoskeleton Journal of Biological Chemistry. 274: 29843-29849. PMID 10514464 DOI: 10.1074/Jbc.274.42.29843  0.457
1999 Orlowski J. Na+/H+ exchangers. Molecular diversity and relevance to heart Annals of the New York Academy of Sciences. 874: 346-353. PMID 10415546 DOI: 10.1111/J.1749-6632.1999.Tb09250.X  0.402
1999 Chow CW, Woodside M, Demaurex N, Yu FH, Plant P, Rotin D, Grinstein S, Orlowski J. Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia. The Journal of Biological Chemistry. 274: 10481-8. PMID 10187839 DOI: 10.1074/Jbc.274.15.10481  0.458
1999 Petrecca K, Atanasiu R, Grinstein S, Orlowski J, Shrier A. Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. The American Journal of Physiology. 276: H709-17. PMID 9950874 DOI: 10.1152/Ajpheart.1999.276.2.H709  0.454
1999 Baird NR, Orlowski J, Szabó EZ, Zaun HC, Schultheis PJ, Menon AG, Shull GE. Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain. The Journal of Biological Chemistry. 274: 4377-82. PMID 9933641 DOI: 10.1074/Jbc.274.7.4377  0.776
1998 Kurashima K, Szabó EZ, Lukacs G, Orlowski J, Grinstein S. Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway. The Journal of Biological Chemistry. 273: 20828-36. PMID 9694828 DOI: 10.1074/Jbc.273.33.20828  0.799
1998 Shrode LD, Gan BS, D'Souza SJA, Orlowski J, Grinstein S. Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage American Journal of Physiology - Cell Physiology. 275. PMID 9688597 DOI: 10.1152/Ajpcell.1998.275.2.C431  0.501
1998 Barr KJ, Garrill A, Jones DH, Orlowski J, Kidder GM. Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse. Molecular Reproduction and Development. 50: 146-53. PMID 9590530 DOI: 10.1002/(Sici)1098-2795(199806)50:2<146::Aid-Mrd4>3.0.Co;2-K  0.453
1998 Numata M, Petrecca K, Lake N, Orlowski J. Identification of a mitochondrial Na+/H+ exchanger. The Journal of Biological Chemistry. 273: 6951-9. PMID 9507001 DOI: 10.1074/Jbc.273.12.6951  0.466
1998 D'Souza S, Garcia-Cabado A, Yu F, Teter K, Lukacs G, Skorecki K, Moore HP, Orlowski J, Grinstein S. The epithelial sodium-hydrogen antiporter Na+/H+ exchanger 3 accumulates and is functional in recycling endosomes. The Journal of Biological Chemistry. 273: 2035-43. PMID 9442041 DOI: 10.1074/Jbc.273.4.2035  0.549
1997 Kurashima K, Yu FH, Cabado AG, Szabó EZ, Grinstein S, Orlowski J. Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms. The Journal of Biological Chemistry. 272: 28672-9. PMID 9353335 DOI: 10.1074/Jbc.272.45.28672  0.802
1997 Orlowski J, Grinstein S. Na+/H+ exchangers of mammalian cells. The Journal of Biological Chemistry. 272: 22373-6. PMID 9278382 DOI: 10.1074/Jbc.272.36.22373  0.475
1997 Demaurex N, Romanek RR, Orlowski J, Grinstein S. ATP dependence of Na+/H+ exchange. Nucleotide specificity and assessment of the role of phospholipids. The Journal of General Physiology. 109: 117-28. PMID 9041442 DOI: 10.1085/Jgp.109.2.117  0.487
1997 Robertson MA, Woodside M, Foskett JK, Orlowski J, Grinstein S. Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells. The Journal of Biological Chemistry. 272: 287-94. PMID 8995260 DOI: 10.1074/Jbc.272.1.287  0.548
1996 Lake N, Orlowski J. Cellular Studies of the Taurine Transporter Advances in Experimental Medicine and Biology. 403: 371-376. PMID 8915373 DOI: 10.1007/978-1-4899-0182-8_39  0.373
1996 Lin X, Voyno-Yasenetskaya TA, Hooley R, Lin CY, Orlowski J, Barber DL. Galpha12 differentially regulates Na+-H+ exchanger isoforms. The Journal of Biological Chemistry. 271: 22604-10. PMID 8798430 DOI: 10.1074/Jbc.271.37.22604  0.531
1996 Orlowski J, Kandasamy RA. Delineation of Transmembrane Domains of the Na+/H+ Exchanger That Confer Sensitivity to Pharmacological Antagonists Journal of Biological Chemistry. 271: 19922-19927. PMID 8702706 DOI: 10.1074/Jbc.271.33.19922  0.437
1996 Azarani A, Goltzman D, Orlowski J. Structurally diverse N-terminal peptides of parathyroid hormone (PTH) and PTH-related peptide (PTHRP) inhibit the Na+/H+ exchanger NHE3 isoform by binding to the PTH/PTHRP receptor type I and activating distinct signaling pathways. Journal of Biological Chemistry. 271: 14931-14936. PMID 8663042 DOI: 10.1074/Jbc.271.25.14931  0.418
1996 Cabado AG, Yu FH, Kapus A, Lukacs G, Grinstein S, Orlowski J. Distinct structural domains confer cAMP sensitivity and ATP dependence to the Na+/H+ exchanger NHE3 isoform. The Journal of Biological Chemistry. 271: 3590-9. PMID 8631966 DOI: 10.1074/Jbc.271.7.3590  0.516
1996 Kandasamy RA, Orlowski J. Genomic Organization and Glucocorticoid Transcriptional Activation of the Rat Na/H Exchanger Nhe3 Gene Journal of Biological Chemistry. 271: 10551-10559. PMID 8631855 DOI: 10.1074/Jbc.271.18.10551  0.387
1995 Klanke CA, Su YR, Callen DF, Wang Z, Meneton P, Baird N, Kandasamy RA, Orlowski J, Otterud BE, Leppert M, Shull GE, Menon AG. Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1 Genomics. 25: 615-622. PMID 7759094 DOI: 10.1016/0888-7543(95)80002-4  0.343
1995 Azarani A, Goltzman D, Orlowski J. Parathyroid Hormone and Parathyroid Hormone-related Peptide Inhibit the Apical Na+/H+ Exchanger NHE-3 Isoform in Renal Cells (OK) via a Dual Signaling Cascade Involving Protein Kinase A and C Journal of Biological Chemistry. 270: 20004-20010. PMID 7650018 DOI: 10.1074/Jbc.270.34.20004  0.529
1995 Wakabayashi S, Ikeda T, Noël J, Schmitt B, Orlowski J, Pouysségur J, Shigekawa M. Cytoplasmic Domain of the Ubiquitous Na+/H+ Exchanger NHE1 Can Confer Ca2+ Responsiveness to the Apical Isoform NHE3 Journal of Biological Chemistry. 270: 26460-26465. PMID 7592862 DOI: 10.1074/Jbc.270.44.26460  0.447
1995 Azarani A, Orlowski J, Goltzman D. Parathyroid Hormone and Parathyroid Hormone-related Peptide Activate the Na+/H+ Exchanger NHE-1 Isoform in Osteoblastic Cells (UMR-106) via a cAMP-dependent Pathway Journal of Biological Chemistry. 270: 23166-23172. PMID 7559463 DOI: 10.1074/Jbc.270.39.23166  0.51
1995 Demaurex N, Orlowski J, Brisseau G, Woodside M, Grinstein S. The mammalian Na+/H+ antiporters NHE-1, NHE-2, and NHE-3 are electroneutral and voltage independent, but can couple to an H+ conductance. The Journal of General Physiology. 106: 85-111. PMID 7494140 DOI: 10.1085/Jgp.106.1.85  0.474
1995 Kandasamy RA, Yu FH, Harris R, Boucher A, Hanrahan JW, Orlowski J. Plasma membrane Na+/H+ exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways. The Journal of Biological Chemistry. 270: 29209-16. PMID 7493949 DOI: 10.1074/Jbc.270.49.29209  0.52
1993 Feng J, Orlowski J, Lingrel JB. Identification of a functional thyroid hormone response element in the upstream flanking region of the human Na,K-ATPase beta 1 gene. Nucleic Acids Research. 21: 2619-26. PMID 8392703 DOI: 10.1093/Nar/21.11.2619  0.379
1993 Giannella RA, Orlowski J, Jump ML, Lingrel JB. Na(+)-K(+)-ATPase gene expression in rat intestine and Caco-2 cells: response to thyroid hormone. The American Journal of Physiology. 265: G775-82. PMID 8238361 DOI: 10.1152/Ajpgi.1993.265.4.G775  0.357
1990 Lingrel JB, Orlowski J, Shull MM, Price EM. Molecular genetics of Na,K-ATPase. Progress in Nucleic Acid Research and Molecular Biology. 38: 37-89. PMID 2158121 DOI: 10.1016/S0079-6603(08)60708-4  0.417
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