Alvin Shrier - Publications

Affiliations: 
Physiology McGill University, Montreal, QC, Canada 
Area:
General Biophysics, Physiology Biology, Bioinformatics Biology

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Biasci V, Sacconi L, Cytrynbaum EN, Pijnappels DA, De Coster T, Shrier A, Glass L, Bub G. Universal mechanisms for self-termination of rapid cardiac rhythm. Chaos (Woodbury, N.Y.). 30: 121107. PMID 33380016 DOI: 10.1063/5.0033813  0.311
2019 Tomek J, Bueno-Orovio A, Passini E, Zhou X, Minchole A, Britton O, Bartolucci C, Severi S, Shrier A, Virag L, Varro A, Rodriguez B. Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block. Elife. 8. PMID 31868580 DOI: 10.7554/Elife.48890  0.318
2019 Ng CA, Perry MD, Liang W, Smith NJ, Foo B, Shrier A, Lukacs GL, Hill AP, Vandenberg JI. High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants. Heart Rhythm. PMID 31557540 DOI: 10.1016/J.Hrthm.2019.09.020  0.321
2019 Cytrynbaum EN, MacKay V, Nahman-Lévesque O, Dobbs M, Bub G, Shrier A, Glass L. Double-wave reentry in excitable media. Chaos (Woodbury, N.Y.). 29: 073103. PMID 31370409 DOI: 10.1063/1.5092982  0.398
2019 Foo B, Barbier C, Guo K, Vasantharuban J, Lukacs GL, Shrier A. Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression. Scientific Reports. 9: 6066. PMID 30988392 DOI: 10.1038/S41598-019-42331-6  0.315
2019 Caldwell BA, Romero Seplvuda M, Bub G, Shrier A. Optogenetic Control of Re-Entrant Waves Demonstrated in Human Induced Stem Cell Derived Cardiomyocytes (hiPSC-CMs) Biophysical Journal. 116: 100a. DOI: 10.1016/J.Bpj.2018.11.576  0.311
2017 You MJ, Langfield P, Campanari L, Dobbs M, Shrier A, Glass L. Demonstration of cardiac rotor and source mapping techniques in embryonic chick monolayers. Chaos (Woodbury, N.Y.). 27: 093938. PMID 28964155 DOI: 10.1063/1.5001459  0.399
2017 Valinsky WC, Touyz RM, Shrier A. Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells. Biochimica Et Biophysica Acta. PMID 28483640 DOI: 10.1016/J.Bbagen.2017.05.004  0.329
2017 Campanari L, You MJ, Langfield P, Glass L, Shrier A. Varieties of reentrant dynamics. Chaos (Woodbury, N.Y.). 27: 041101. PMID 28456163 DOI: 10.1063/1.4979602  0.395
2016 Hantouche C, Williamson B, Valinsky WC, Solomon J, Shrier A, Young JC. Bag1 Promotes TRC8-Dependent Degradation of Misfolded hERG Potassium Channels. The Journal of Biological Chemistry. PMID 27998983 DOI: 10.1074/Jbc.M116.752618  0.332
2016 Guevara MR, Shrier A, Orlowski J, Glass L. George Ralph Mines (1886-1914): the dawn of cardiac nonlinear dynamics. The Journal of Physiology. 594: 2361-71. PMID 27126414 DOI: 10.1113/Jp270891  0.313
2016 Quail T, Shrier A, Glass L. Predicting the Onset of Alternating Rhythms in Noisy Cardiac Systems Biophysical Journal. 110: 479a. DOI: 10.1016/J.Bpj.2015.11.2561  0.365
2016 Valinsky WC, Touyz RM, Shrier A. Acid-Induced Chloride Current in Distal Convoluted Tubule Biophysical Journal. 110: 353a. DOI: 10.1016/J.Bpj.2015.11.1904  0.309
2015 Quail T, Shrier A, Glass L. Predicting the onset of period-doubling bifurcations in noisy cardiac systems. Proceedings of the National Academy of Sciences of the United States of America. 112: 9358-63. PMID 26170301 DOI: 10.1073/Pnas.1424320112  0.395
2015 Glass L, Shrier A. Functional characterization of oscillatory and excitable media. Bulletin of Mathematical Biology. 77: 782-95. PMID 25266320 DOI: 10.1007/S11538-014-0015-Y  0.356
2014 Quail T, Shrier A, Glass L. Spatial symmetry breaking determines spiral wave chirality. Physical Review Letters. 113: 158101. PMID 25375745 DOI: 10.1103/Physrevlett.113.158101  0.36
2013 Apaja PM, Foo B, Okiyoneda T, Valinsky WC, Barriere H, Atanasiu R, Ficker E, Lukacs GL, Shrier A. Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane. Molecular Biology of the Cell. 24: 3787-804. PMID 24152733 DOI: 10.1091/Mbc.E13-07-0417  0.347
2013 Shajahan TK, Borek B, Shrier A, Glass L. Spiral–pacemaker interactions in a mathematical model of excitable medium New Journal of Physics. 15: 023028. DOI: 10.1088/1367-2630/15/2/023028  0.726
2012 Quail T, McVicar N, Aguilar M, Kim MY, Hodge A, Glass L, Shrier A. Chaotic dynamics in cardiac aggregates induced by potassium channel block. Chaos (Woodbury, N.Y.). 22: 033140. PMID 23020479 DOI: 10.1063/1.4748854  0.405
2012 Borek B, Shajahan TK, Gabriels J, Hodge A, Glass L, Shrier A. Pacemaker interactions induce reentrant wave dynamics in engineered cardiac culture. Chaos (Woodbury, N.Y.). 22: 033132. PMID 23020471 DOI: 10.1063/1.4747709  0.746
2012 Apaja PM, Okiyondea T, Barriere H, Lam H, Atanasiu R, Foo B, Ficker E, Lukacs GL, Shrier A. hERG Quality Control at the Plasma Membrane Biophysical Journal. 102: 677a. DOI: 10.1016/J.Bpj.2011.11.3683  0.311
2011 Shajahan TK, Borek B, Shrier A, Glass L. Scaling properties of conduction velocity in heterogeneous excitable media. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 84: 046208. PMID 22181246 DOI: 10.1103/Physreve.84.046208  0.736
2011 Glass L, Lerma C, Shrier A. New methods for the analysis of heartbeat behavior in risk stratification. Frontiers in Physiology. 2: 88. PMID 22144963 DOI: 10.3389/Fphys.2011.00088  0.336
2010 Walker VE, Wong MJ, Atanasiu R, Hantouche C, Young JC, Shrier A. Hsp40 chaperones promote degradation of the HERG potassium channel. The Journal of Biological Chemistry. 285: 3319-29. PMID 19940115 DOI: 10.1074/Jbc.M109.024000  0.342
2009 Kim MY, Aguilar M, Hodge A, Vigmond E, Shrier A, Glass L. Stochastic and spatial influences on drug-induced bifurcations in cardiac tissue culture. Physical Review Letters. 103: 058101. PMID 19792536 DOI: 10.1103/Physrevlett.103.058101  0.381
2009 Walker V, Young J, Shrier A. hERG Trafficking is Dependent on a Cytosolic Chaperone Network Biophysical Journal. 96: 105a. DOI: 10.1016/J.Bpj.2008.12.452  0.332
2009 Lam HD, Atanasiu R, Okiyoneda T, Barriere H, Lukacs GL, Shrier A. Reduced Cell Surface Stability Of Rescued Herg Trafficking Mutants Biophysical Journal. 96: 331a. DOI: 10.1016/J.Bpj.2008.12.1669  0.358
2008 Zaun HC, Shrier A, Orlowski J. Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform. The Journal of Biological Chemistry. 283: 12456-67. PMID 18321853 DOI: 10.1074/Jbc.M800267200  0.312
2007 Walker VE, Atanasiu R, Lam H, Shrier A. Co-chaperone FKBP38 promotes HERG trafficking. The Journal of Biological Chemistry. 282: 23509-16. PMID 17569659 DOI: 10.1074/Jbc.M701006200  0.356
2006 Han W, Nattel S, Noguchi T, Shrier A. C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2. The Journal of Biological Chemistry. 281: 27134-44. PMID 16820361 DOI: 10.1074/Jbc.M604843200  0.319
2006 Steinberg BE, Glass L, Shrier A, Bub G. The role of heterogeneities and intercellular coupling in wave propagation in cardiac tissue. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1299-311. PMID 16608709 DOI: 10.1098/Rsta.2006.1771  0.439
2005 Akhavan A, Atanasiu R, Noguchi T, Han W, Holder N, Shrier A. Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization. Journal of Cell Science. 118: 2803-12. PMID 15961404 DOI: 10.1242/Jcs.02423  0.319
2005 Bub G, Shrier A, Glass L. Global organization of dynamics in oscillatory heterogeneous excitable media. Physical Review Letters. 94: 028105. PMID 15698236 DOI: 10.1103/Physrevlett.94.028105  0.369
2004 Bub G, Shrier A, Glass L. Global organization of dynamics in cultured cardiac monolayers. Chaos (Woodbury, N.Y.). 14: S14. PMID 15568898 DOI: 10.1063/1.1821772  0.305
2003 Bub G, Tateno K, Shrier A, Glass L. Spontaneous initiation and termination of complex rhythms in cardiac cell culture. Journal of Cardiovascular Electrophysiology. 14: S229-36. PMID 14760928 DOI: 10.1046/J.1540.8167.90315.X  0.353
2003 González H, Nagai Y, Bub G, Glass L, Shrier A. Reentrant waves in a ring of embryonic chick ventricular cells imaged with a Ca2+ sensitive dye. Bio Systems. 71: 71-80. PMID 14568208 DOI: 10.1016/S0303-2647(03)00111-4  0.438
2003 Akhavan A, Atanasiu R, Shrier A. Identification of a COOH-terminal segment involved in maturation and stability of human ether-a-go-go-related gene potassium channels. The Journal of Biological Chemistry. 278: 40105-12. PMID 12885765 DOI: 10.1074/Jbc.M307837200  0.359
2002 Bub G, Shrier A. Propagation through heterogeneous substrates in simple excitable media models. Chaos (Woodbury, N.Y.). 12: 747-753. PMID 12779603 DOI: 10.1063/1.1502481  0.365
2002 Li GR, Lau CP, Shrier A. Heterogeneity of sodium current in atrial vs epicardial ventricular myocytes of adult guinea pig hearts. Journal of Molecular and Cellular Cardiology. 34: 1185-94. PMID 12392892 DOI: 10.1006/Jmcc.2002.2053  0.383
2002 Melnyk P, Zhang L, Shrier A, Nattel S. Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1123-33. PMID 12181143 DOI: 10.1152/Ajpheart.00934.2001  0.335
2002 Bub G, Shrier A, Glass L. Spiral wave generation in heterogeneous excitable media. Physical Review Letters. 88: 058101. PMID 11863783 DOI: 10.1103/Physrevlett.88.058101  0.397
2001 Baroudi G, Pouliot V, Denjoy I, Guicheney P, Shrier A, Chahine M. Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G). Circulation Research. 88: E78-83. PMID 11420310 DOI: 10.1161/Hh1201.093270  0.356
2000 Petrecca K, Miller DM, Shrier A. Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8736-44. PMID 11102480 DOI: 10.1523/Jneurosci.20-23-08736.2000  0.607
2000 Nagai Y, González H, Shrier A, Glass L. Paroxysmal starting and stopping of circulating waves in excitable media. Physical Review Letters. 84: 4248-51. PMID 10990657 DOI: 10.1103/Physrevlett.84.4248  0.418
2000 Li D, Melnyk P, Feng J, Wang Z, Petrecca K, Shrier A, Nattel S. Effects of experimental heart failure on atrial cellular and ionic electrophysiology. Circulation. 101: 2631-8. PMID 10840016 DOI: 10.1161/01.Cir.101.22.2631  0.587
2000 Pond AL, Scheve BK, Benedict AT, Petrecca K, Van Wagoner DR, Shrier A, Nerbonne JM. Expression of distinct ERG proteins in rat, mouse, and human heart. Relation to functional I(Kr) channels Journal of Biological Chemistry. 275: 5997-6006. PMID 10681594 DOI: 10.1074/Jbc.275.8.5997  0.614
2000 González H, Nagai Y, Bub G, Glass L, Shrier A. Resetting and Annihilating Reentrant Waves in a Ring of Cardiac Tissue: Theory and Experiment Progress of Theoretical Physics Supplement. 139: 83-89. DOI: 10.1143/Ptps.139.83  0.364
1999 Petrecca K, Atanasiu R, Grinstein S, Orlowski J, Shrier A. Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. The American Journal of Physiology. 276: H709-17. PMID 9950874 DOI: 10.1152/Ajpheart.1999.276.2.H709  0.61
1999 Petrecca K, Atanasiu R, Akhavan A, Shrier A. N-linked glycosylation sites determine HERG channel surface membrane expression. The Journal of Physiology. 515: 41-8. PMID 9925876 DOI: 10.1111/J.1469-7793.1999.041Ad.X  0.594
1998 Petrecca K, Shrier A. Spatial distribution of nerve processes and beta-adrenoreceptors in the rat atrioventricular node. Journal of Anatomy. 192: 517-28. PMID 9723979 DOI: 10.1046/J.1469-7580.1998.19240517.X  0.577
1998 Bub G, Glass L, Publicover NG, Shrier A. Bursting calcium rotors in cultured cardiac myocyte monolayers Proceedings of the National Academy of Sciences of the United States of America. 95: 10283-10287. PMID 9707639 DOI: 10.1073/Pnas.95.17.10283  0.417
1998 Paquette T, Clay JR, Ogbaghebriel A, Shrier A. Effects of divalent cations on the E-4031-sensitive repolarization current, I(Kr), in rabbit ventricular myocytes. Biophysical Journal. 74: 1278-85. PMID 9512025 DOI: 10.1016/S0006-3495(98)77841-5  0.356
1998 Orlowski J, Petrecca K, Atanasiu R, Grinstein S, Shrier A. Molecular and cellular characterization of the myocardial Na+/H+ exchanger Pathophysiology. 5: 37. DOI: 10.1016/S0928-4680(98)80419-7  0.508
1997 Kunysz AM, Shrier A, Glass L. Bursting behavior during fixed-delay stimulation of spontaneously beating chick heart cell aggregates. The American Journal of Physiology. 273: C331-46. PMID 9252472 DOI: 10.1152/Ajpcell.1997.273.1.C331  0.393
1997 Yehia AR, Shrier A, Lo KC, Guevara MR. Transient outward current contributes to Wenckebach-like rhythms in isolated rabbit ventricular cells. The American Journal of Physiology. 273: H1-11. PMID 9249468 DOI: 10.1152/Ajpheart.1997.273.1.H1  0.366
1997 Petrecca K, Amellal F, Laird DW, Cohen SA, Shrier A. Sodium channel distribution within the rabbit atrioventricular node as analysed by confocal microscopy. The Journal of Physiology. 501: 263-74. PMID 9192299 DOI: 10.1111/J.1469-7793.1997.263Bn.X  0.6
1997 Kunysz A, Shrier A, Glass L. The Challenge of Complex Dynamics for Theoretical Models of Cardiac Activity Journal of Theoretical Medicine. 1: 79-90. DOI: 10.1080/10273669708833009  0.386
1996 Munk AA, Adjemian RA, Zhao J, Ogbaghebriel A, Shrier A. Electrophysiological properties of morphologically distinct cells isolated from the rabbit atrioventricular node. The Journal of Physiology. 493: 801-18. PMID 8799901 DOI: 10.1113/Jphysiol.1996.Sp021424  0.332
1995 Kunysz AM, Munk AA, Shrier A. Phase resetting and dynamics in isolated atrioventricular nodal cell clusters. Chaos (Woodbury, N.Y.). 5: 184-192. PMID 12780172 DOI: 10.1063/1.166066  0.323
1995 Clay JR, Kristof AS, Shenasa J, Brochu RM, Shrier A. A review of the effects of three cardioactive agents on the electrical activity from embryonic chick heart cell aggregates: TTX, ACh, and E-4031. Progress in Biophysics and Molecular Biology. 62: 185-202. PMID 7892502 DOI: 10.1016/0079-6107(94)90011-6  0.314
1995 Kunysz A, Glass L, Shrier A. Overdrive suppression of spontaneously beating chick heart cell aggregates: experiment and theory. The American Journal of Physiology. 269: H1153-64. PMID 7573512 DOI: 10.1152/Ajpheart.1995.269.3.H1153  0.335
1994 Ogbaghebriel A, Shrier A. Inhibition of metabolism abolishes transient outward current in rabbit atrial myocytes. The American Journal of Physiology. 266: H182-90. PMID 8304498 DOI: 10.1152/Ajpheart.1994.266.1.H182  0.312
1994 Kowtha VC, Kunysz A, Clay JR, Glass L, Shrier A. Ionic mechanisms and nonlinear dynamics of embryonic chick heart cell aggregates. Progress in Biophysics and Molecular Biology. 61: 255-81. PMID 8073123 DOI: 10.1016/0079-6107(94)90002-7  0.341
1993 Brochu RM, Clay JR, Shrier A. Pacemaker current in single cells and in aggregates of cells dissociated from the embryonic chick heart. The Journal of Physiology. 454: 503-15. PMID 1474500 DOI: 10.1113/Jphysiol.1992.Sp019276  0.327
1992 Zeng W, Glass L, Shrier A. The topology of phase response curves induced by single and paired stimuli in spontaneously oscillating chick heart cell aggregates. Journal of Biological Rhythms. 7: 89-104. PMID 1611132 DOI: 10.1177/074873049200700201  0.308
1991 Zeng WZ, Glass L, Shrier A. Evolution of rhythms during periodic stimulation of embryonic chick heart cell aggregates. Circulation Research. 69: 1022-33. PMID 1934330 DOI: 10.1161/01.Res.69.4.1022  0.344
1991 Hill CE, Shrier A. Voltage-dependent inactivation of the potassium current of embryonic chick hepatocytes Canadian Journal of Physiology and Pharmacology. 69: 739-745. PMID 1913320 DOI: 10.1139/Y91-110  0.325
1990 Zeng WZ, Courtemanche M, Sehn L, Shrier A, Glass L. Theoretical computation of phase locking in embryonic atrial heart cell aggregates Journal of Theoretical Biology. 145: 225-244. PMID 2402157 DOI: 10.1016/S0022-5193(05)80128-6  0.33
1990 Guevara MR, Shrier A. Rhythms produced by high-amplitude periodic stimulation of spontaneously beating aggregates of embryonic chick ventricular myocytes. Annals of the New York Academy of Sciences. 591: 11-22. PMID 2375574 DOI: 10.1111/J.1749-6632.1990.Tb15077.X  0.327
1990 Shrier A, Clay JR, Brochu RM. Effects of tetrodotoxin on heart cell aggregates. Phase resetting and annihilation of activity. Biophysical Journal. 58: 623-9. PMID 2207254 DOI: 10.1016/S0006-3495(90)82405-X  0.354
1990 Wanzhen Z, Morissette J, Brochu R, Glass L, Shrier A. NASPE young investigator awardee-1990. Complex rhythms resulting from overdrive suppression in electrically stimulated heart cell aggregates. Pacing and Clinical Electrophysiology : Pace. 13: 1678-85. PMID 1704522 DOI: 10.1111/J.1540-8159.1990.Tb06871.X  0.354
1989 Clay JR, Hill CE, Roitman D, Shrier A. Repolarization current in embryonic chick atrial heart cells. The Journal of Physiology. 403: 525-37. PMID 3253425 DOI: 10.1113/Jphysiol.1988.Sp017262  0.371
1989 Cooper E, Shrier A. Inactivation of A currents and A channels on rat nodose neurons in culture Journal of General Physiology. 94: 881-910. PMID 2592953 DOI: 10.1085/Jgp.94.5.881  0.333
1988 Guevara MR, Shrier A, Glass L. Phase-locked rhythms in periodically stimulated heart cell aggregates. The American Journal of Physiology. 254: H1-10. PMID 3337247 DOI: 10.1152/Ajpheart.1988.254.1.H1  0.314
1987 Guevara MR, Shrier A, Glass L. Phase resetting of spontaneously beating embryonic ventricular heart cell aggregates. The American Journal of Physiology. 251: H1298-305. PMID 3789182 DOI: 10.1152/Ajpheart.1986.251.6.H1298  0.328
1987 Guevara MR, Shrier A. Phase resetting in a model of cardiac Purkinje fiber. Biophysical Journal. 52: 165-75. PMID 3663827 DOI: 10.1016/S0006-3495(87)83204-6  0.317
1987 Glass L, Guevara MR, Shrier A. Universal bifurcations and the classification of cardiac arrhythmias. Annals of the New York Academy of Sciences. 504: 168-78. PMID 3477114 DOI: 10.1111/J.1749-6632.1987.Tb48731.X  0.392
1987 Glass L, Goldberger AL, Courtemanche M, Shrier A. Nonlinear Dynamics, Chaos and Complex Cardiac Arrhythmias Proceedings of the Royal Society a: Mathematical, Physical and Engineering Sciences. 413: 9-26. DOI: 10.1098/Rspa.1987.0097  0.393
1986 Bacaner MB, Clay JR, Shrier A, Brochu RM. Potassium channel blockade: A mechanism for suppressing ventricular fibrillation. Proceedings of the National Academy of Sciences of the United States of America. 83: 2223-7. PMID 2421289 DOI: 10.1073/Pnas.83.7.2223  0.369
1984 Clay JR, Guevara MR, Shrier A. Phase resetting of the rhythmic activity of embryonic heart cell aggregates. Experiment and theory. Biophysical Journal. 45: 699-714. PMID 6722263 DOI: 10.1016/S0006-3495(84)84212-5  0.342
1983 Colizza D, Guevara MR, Shrier A. A comparative study of collagenase- and trypsin-dissociated embryonic heart cells: reaggregation, electrophysiology, and pharmacology. Canadian Journal of Physiology and Pharmacology. 61: 408-19. PMID 6305468 DOI: 10.1139/Y83-062  0.352
1983 Glass L, Guevara MR, Shrier A, Perez R. Bifurcation and chaos in a periodically stimulated cardiac oscillator Physica D: Nonlinear Phenomena. 7: 89-101. DOI: 10.1016/0167-2789(83)90119-7  0.32
1983 Shrier A, Clay J, Guevara M, Glass L. Ionic current analysis of phase resetting in embryonic heart cell aggregates☆ Journal of Molecular and Cellular Cardiology. 15: 84-84. DOI: 10.1016/0022-2828(83)91023-4  0.345
1982 Guevara MR, Glass L, Shrier A. Phase locking, period-doubling bifurcations, and irregular dynamics in periodically stimulated cardiac cells. Science (New York, N.Y.). 214: 1350-3. PMID 7313693 DOI: 10.1126/Science.7313693  0.35
1982 Shrier A, Clay JR. Comparison of the pacemaker properties of chick embryonic atrial and ventricular heart cells. The Journal of Membrane Biology. 69: 49-56. PMID 7120363 DOI: 10.1007/Bf01871241  0.387
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