Year |
Citation |
Score |
2020 |
Bekeova C, Anderson-Pullinger L, Boye K, Sharpadskaya Y, Seifert E. Mitochondrial Thioesterases: Localization, Regulation and Functional Relevance of Acyl‐CoA Thioesterase 2 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09470 |
0.342 |
|
2019 |
Bekeova C, Anderson-Pullinger L, Boye K, Boos F, Sharpadskaya Y, Herrmann JM, Seifert EL. Multiple mitochondrial thioesterases have distinct tissue and substrate specificity, and CoA regulation, suggesting unique functional roles. The Journal of Biological Chemistry. PMID 31676684 DOI: 10.1074/Jbc.Ra119.010901 |
0.361 |
|
2019 |
Debattisti V, Horn A, Singh R, Seifert EL, Hogarth MW, Mazala DA, Huang KT, Horvath R, Jaiswal JK, Hajnóczky G. Dysregulation of Mitochondrial Ca Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1. Cell Reports. 29: 1274-1286.e6. PMID 31665639 DOI: 10.1016/J.Celrep.2019.09.063 |
0.398 |
|
2018 |
Zhi L, Qin Q, Muqeem T, Seifert EL, Liu W, Zheng S, Li C, Zhang H. Loss of PINK1 causes age-dependent decrease of dopamine release and mitochondrial dysfunction. Neurobiology of Aging. 75: 1-10. PMID 30504091 DOI: 10.1016/J.Neurobiolaging.2018.10.025 |
0.308 |
|
2018 |
Gubbiotti MA, Seifert EL, Rodeck U, Hoek JB, Iozzo RV. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor, decorin. The Journal of Biological Chemistry. PMID 30049794 DOI: 10.1074/Jbc.Ra118.004563 |
0.315 |
|
2018 |
Seifert E, Anderson-Pullinger L, Sharpadskaya Y. Loss of Mitochondrial Phosphate Carrier in Skeletal Muscle: Dissociation of Muscle Dysfunction from Lower ADP Phosphorylating Potential Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3557 |
0.307 |
|
2018 |
Seifert EL, Anderson-Pullinger L, Debattisti V, Sharpadskaya Y, Hajnoczky G. Loss of mitochondrial phosphate carrier SLC25A3 in skeletal muscle provides evidence for compensatory but lower capacity phosphate uptake into mitochondria Biochimica Et Biophysica Acta. 1859. DOI: 10.1016/J.Bbabio.2018.09.290 |
0.348 |
|
2017 |
Silagi ES, Schoepflin ZR, Seifert EL, Merceron C, Schipani E, Shapiro IM, Risbud MV. Bicarbonate Recycling by HIF-1-dependent Carbonic Anhydrase isoforms 9 and 12 is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28940640 DOI: 10.1002/Jbmr.3293 |
0.301 |
|
2017 |
Gal A, Balicza P, Weaver D, Naghdi S, Joseph SK, Várnai P, Gyuris T, Horváth A, Nagy L, Seifert EL, Molnar MJ, Hajnóczky G. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans. Embo Molecular Medicine. PMID 28554942 DOI: 10.15252/Emmm.201607058 |
0.369 |
|
2017 |
Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell T, Bisetto S, Velasco-Velàzquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, et al. Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK-LKB1 signaling axis. Cancer Research. PMID 28522753 DOI: 10.1158/0008-5472.Can-16-0425 |
0.314 |
|
2017 |
Paillard M, Csordás G, Szanda G, Golenár T, Debattisti V, Bartok A, Wang N, Moffat C, Seifert EL, Spät A, Hajnóczky G. Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca(2+) Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU. Cell Reports. 18: 2291-2300. PMID 28273446 DOI: 10.1016/J.Celrep.2017.02.032 |
0.384 |
|
2017 |
Debattisti V, Csordas G, Seifert E, Hajnoczky G. Mitochondrial Calcium Uptake and Matrix Calcium Buffering in Skeletal Muscle Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.725 |
0.374 |
|
2017 |
Seifert E, Debattisti V, Hajnoczky G. Alternate Pathways for Inorganic Phosphate Uptake into Mitochondria Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2344 |
0.389 |
|
2016 |
Seifert EL, Gál A, Acoba MG, Li Q, Anderson-Pullinger L, Golenár T, Moffat C, Sondheimer N, Claypool SM, Hajnóczky G. Natural and induced mitochondrial phosphate carrier loss: differential dependence of mitochondrial metabolism and dynamics, and cell survival, on the extent of depletion. The Journal of Biological Chemistry. PMID 27780865 DOI: 10.1074/Jbc.M116.744714 |
0.38 |
|
2016 |
Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nature Communications. 7: 10955. PMID 26956930 DOI: 10.1038/Ncomms10955 |
0.388 |
|
2016 |
Seifert E, Gal A, Acoba MG, Claypool SM, Anderson-Pullinger L, Varnai P, Moffat C, Weaver D, Sondheimer N, Hajnoczky G. Novel Mutations in SLC25A3 Encoding the Mitochondrial Phosphate Carrier Biophysical Journal. 110: 474a. DOI: 10.1016/J.Bpj.2015.11.2536 |
0.372 |
|
2016 |
Antony AN, Paillard M, Moffat C, Juskeviciute E, Rubin E, Csordas G, Seifert E, Hajnoczky G, Hoek JB. MICU1 Regulation of Mitochondrial Calcium Uptake is Crucial for Liver Regeneration Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1672 |
0.376 |
|
2016 |
Paillard M, Antony AN, Moffat C, Juskeviciute E, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G. MICU1, the Ca2+ Sensing Regulator of the Mitochondrial Ca2+ Uniporter is Required for Adaptation to Postnatal Life Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1671 |
0.386 |
|
2016 |
Debattisti V, Paillard M, Csordas G, Seifert E, Hajnoczky G. Characterization of Mitochondrial Calcium Uptake in Skeletal Muscle Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1421 |
0.386 |
|
2016 |
Hajnóczky G, Paillard M, Csordás G, Debattisti V, Bartók Á, Moffat C, Seifert EL. Dependence of mitochondrial Ca2 + uptake on the molecular composition of the uniporter Biochimica Et Biophysica Acta. 1857. DOI: 10.1016/J.Bbabio.2016.04.383 |
0.35 |
|
2015 |
Picard M, McManus MJ, Gray JD, Nasca C, Moffat C, Kopinski PK, Seifert EL, McEwen BS, Wallace DC. Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences of the United States of America. 112: E6614-23. PMID 26627253 DOI: 10.1073/Pnas.1515733112 |
0.363 |
|
2015 |
Seifert EL, Ligeti E, Mayr JA, Sondheimer N, Hajnóczky G. The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease. Biochemical and Biophysical Research Communications. 464: 369-75. PMID 26091567 DOI: 10.1016/J.Bbrc.2015.06.031 |
0.373 |
|
2015 |
Seifert EL, Gál A, Várnai P, Moffat C, Weaver D, Sondheimer N, Hajnóczky G. Novel mutations in SLC25A3 encoding the mitochondrial phosphate carrier Mitochondrion. 24. DOI: 10.1016/J.Mito.2015.07.087 |
0.307 |
|
2015 |
Paillard M, Csordás G, Golenár T, Moffat C, Seifert E, Hajnóczky G. The Stoichiometry between MICU1 and MCU Determines the Different Mitochondrial Ca2+ Uptake Phenotypes in Heart and Liver Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.3318 |
0.372 |
|
2014 |
Fried NT, Moffat C, Seifert EL, Oshinsky ML. Functional mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of migraine. American Journal of Physiology. Cell Physiology. 307: C1017-30. PMID 25252946 DOI: 10.1152/Ajpcell.00332.2013 |
0.341 |
|
2014 |
Thrush AB, Zhang R, Chen W, Seifert EL, Quizi JK, McPherson R, Dent R, Harper ME. Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans. The Journal of Clinical Endocrinology and Metabolism. 99: 4223-30. PMID 25148230 DOI: 10.1210/Jc.2014-1726 |
0.353 |
|
2014 |
Moffat C, Bhatia L, Nguyen T, Lynch P, Wang M, Wang D, Ilkayeva OR, Han X, Hirschey MD, Claypool SM, Seifert EL. Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver. Journal of Lipid Research. 55: 2458-70. PMID 25114170 DOI: 10.1194/Jlr.M046961 |
0.353 |
|
2014 |
Hajnóczky G, Booth D, Csordás G, Debattisti V, Golenár T, Naghdi S, Niknejad N, Paillard M, Seifert EL, Weaver D. Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers. Current Opinion in Cell Biology. 29: 133-41. PMID 24999559 DOI: 10.1016/J.Ceb.2014.06.002 |
0.355 |
|
2014 |
Golenár T, Csordás G, Szanda G, Moffat C, Seifert EL, Spät A, Hajnóczky G. Control of Mitochondrial Ca2+ Uptake Threshold via the Micu1:Mcu Ratio Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3275 |
0.316 |
|
2013 |
Aguer C, Fiehn O, Seifert EL, Bézaire V, Meissen JK, Daniels A, Scott K, Renaud JM, Padilla M, Bickel DR, Dysart M, Adams SH, Harper ME. Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4213-25. PMID 23825224 DOI: 10.1096/Fj.13-234302 |
0.315 |
|
2013 |
Csordás G, Golenár T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F, Moffat C, Weaver D, de la Fuente Perez S, Bogorad R, Koteliansky V, Adijanto J, Mootha VK, Hajnóczky G. MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter. Cell Metabolism. 17: 976-87. PMID 23747253 DOI: 10.1016/J.Cmet.2013.04.020 |
0.343 |
|
2013 |
Seifert E, Moffat C, Strus E. Mouse Embryonic Fibroblasts Devoid of both Mitofusin1 and Mitofusin2 can Acutely Shift from Glycolytic to Oxidative Metabolism Biophysical Journal. 104: 659. DOI: 10.1016/J.Bpj.2012.11.3635 |
0.39 |
|
2013 |
Csordás G, Seifert EL, Golenár T, Moffat C, Perez SdlF, Weaver D, Bogorad R, Koteliansky V, Mootha VK, Hajnóczky G. MICU1-dependent Threshold and Cooperativity of Mitochondrial Ca2+ Uptake in the Liver Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3619 |
0.395 |
|
2013 |
Golenár T, Csordás G, Seifert EL, Moffat C, Perocchi F, Sancak Y, Weaver D, Mootha VK, Hajnóczky G. Reprogramming of Mitochondrial Ca2+ Handling in MICU1-Deficient HeLa Cells Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3618 |
0.334 |
|
2013 |
Noronha Antony A, Moffat C, Swarup A, Seifert E, Hoek JB. Substrate Oxidation Control of Respiratory Rates in Primary Hepatocytes Biophysical Journal. 104: 302a. DOI: 10.1016/J.Bpj.2012.11.1684 |
0.338 |
|
2012 |
Seifert EL, Bastianelli M, Aguer C, Moffat C, Estey C, Koch LG, Britton SL, Harper ME. Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 1624-34. PMID 22995392 DOI: 10.1152/Japplphysiol.01475.2011 |
0.396 |
|
2012 |
Estey C, Seifert EL, Aguer C, Moffat C, Harper ME. Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response. Experimental Gerontology. 47: 361-71. PMID 22406134 DOI: 10.1016/J.Exger.2012.02.008 |
0.336 |
|
2012 |
Seifert EL, Csordas G, Golenar T, Moffat C, Perocchi F, Mootha VK, Hajnoczky G. Changes in Mitochondrial Oxygen Consumption can Associate with Increases in Total Mitochondrial Calcium Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.890 |
0.374 |
|
2012 |
Csordás G, Golenár T, Seifert EL, Perocchi F, Mootha VK, Hajnózky G. MICU1 Serves as a Ca2+-Controlled Gatekeeper for the Mitochondrial Ca2+ Uniporter Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.889 |
0.318 |
|
2011 |
Mailloux RJ, Seifert EL, Bouillaud F, Aguer C, Collins S, Harper ME. Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3. The Journal of Biological Chemistry. 286: 21865-75. PMID 21515686 DOI: 10.1074/Jbc.M111.240242 |
0.356 |
|
2011 |
Lidell ME, Seifert EL, Westergren R, Heglind M, Gowing A, Sukonina V, Arani Z, Itkonen P, Wallin S, Westberg F, Fernandez-Rodriguez J, Laakso M, Nilsson T, Peng XR, Harper ME, et al. The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function. Diabetes. 60: 427-35. PMID 21270254 DOI: 10.2337/Db10-0409 |
0.346 |
|
2010 |
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Molecular Genetics. 19: 3734-46. PMID 20639397 DOI: 10.1093/Hmg/Ddq288 |
0.358 |
|
2010 |
Seifert EL, Fiehn O, Bezaire V, Bickel DR, Wohlgemuth G, Adams SH, Harper ME. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. Plos One. 5: e9834. PMID 20352092 DOI: 10.1371/Journal.Pone.0009834 |
0.343 |
|
2010 |
Bevilacqua L, Seifert EL, Estey C, Gerrits MF, Harper ME. Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice. Biochimica Et Biophysica Acta. 1797: 1389-97. PMID 20206124 DOI: 10.1016/J.Bbabio.2010.02.018 |
0.374 |
|
2010 |
Seifert EL, Estey C, Xuan JY, Harper ME. Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation. The Journal of Biological Chemistry. 285: 5748-58. PMID 20032466 DOI: 10.1074/Jbc.M109.026203 |
0.357 |
|
2009 |
Estey C, Seifert EL, Harper M. Mitochondrial uncoupling and remodelling during caloric restriction: Implications for oxidative stress and aging The Faseb Journal. 23. DOI: 10.20381/Ruor-12563 |
0.317 |
|
2008 |
Seifert EL, Bézaire V, Estey C, Harper ME. Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export. The Journal of Biological Chemistry. 283: 25124-31. PMID 18628202 DOI: 10.1074/Jbc.M803871200 |
0.363 |
|
2008 |
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW. SirT1 regulates energy metabolism and response to caloric restriction in mice. Plos One. 3: e1759. PMID 18335035 DOI: 10.1371/Journal.Pone.0001759 |
0.317 |
|
2008 |
Harper ME, Seifert EL. Thyroid hormone effects on mitochondrial energetics. Thyroid : Official Journal of the American Thyroid Association. 18: 145-56. PMID 18279015 DOI: 10.1089/Thy.2007.0250 |
0.307 |
|
2007 |
Bézaire V, Seifert EL, Harper ME. Uncoupling protein-3: clues in an ongoing mitochondrial mystery. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 312-24. PMID 17202247 DOI: 10.1096/Fj.06-6966Rev |
0.351 |
|
2002 |
Seifert EL, Mortola JP. Circadian pattern of ventilation during prolonged hypoxia in conscious rats. Respiratory Physiology & Neurobiology. 133: 23-34. PMID 12385728 DOI: 10.1016/S1569-9048(02)00132-5 |
0.551 |
|
2002 |
Mortola JP, Seifert EL. Circadian patterns of breathing. Respiratory Physiology & Neurobiology. 131: 91-100. PMID 12106998 DOI: 10.1016/S1569-9048(02)00040-X |
0.563 |
|
2002 |
Seifert EL, Mortola JP. The circadian pattern of breathing in conscious adult rats. Respiration Physiology. 129: 297-305. PMID 11788133 DOI: 10.1016/S0034-5687(01)00316-4 |
0.548 |
|
2002 |
Seifert EL, Mortola JP. Circadian pattern of ventilation during acute and chronic hypercapnia in conscious adult rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R244-51. PMID 11742844 DOI: 10.1152/Ajpregu.00290.2001 |
0.544 |
|
2000 |
Fenelon K, Seifert EL, Mortola JP. Hypoxic depression of circadian oscillations in sino-aortic denervated rats. Respiration Physiology. 122: 61-9. PMID 10936601 DOI: 10.1016/S0034-5687(00)00118-3 |
0.54 |
|
2000 |
Seifert EL, Mortola JP. Light-dark differences in the effects of ambient temperature on gaseous metabolism in newborn rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 88: 1853-8. PMID 10797150 DOI: 10.1152/Jappl.2000.88.5.1853 |
0.525 |
|
2000 |
Seifert EL, Knowles J, Mortola JP. Continuous circadian measurements of ventilation in behaving adult rats. Respiration Physiology. 120: 179-83. PMID 10773247 DOI: 10.1016/S0034-5687(00)00108-0 |
0.536 |
|
2000 |
Mortola JP, Seifert EL. Hypoxic depression of circadian rhythms in adult rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 88: 365-8. PMID 10657999 DOI: 10.1152/Jappl.2000.88.2.365 |
0.54 |
|
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