George Paul Hess, A.B., Ph.D. - Publications

Affiliations: 
Molecular Biology & Genetics Cornell University, Ithaca, NY, United States 
Area:
caged neurotransmitters, photolysis, kinetics, nicotinic acetylcholine, GABA(A), NMDA, glutamate, glycine, receptors, inhibitors, epilepsy
Website:
http://www.news.cornell.edu/stories/2015/09/george-hess-biochemist-dies-92

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Hess GP, Lewis RW, Chen Y. Caged neurotransmitters and other caged compounds: design and application. Cold Spring Harbor Protocols. 2014: pdb.top084152. PMID 25275116 DOI: 10.1101/pdb.top084152  1
2014 Hess GP, Lewis RW, Chen Y. Cell-flow technique. Cold Spring Harbor Protocols. 2014: pdb.prot084160. PMID 25275111 DOI: 10.1101/pdb.prot084160  1
2011 Lewis RW, Hess GP, Ganem B. Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. Future Medicinal Chemistry. 3: 243-50. PMID 21428818 DOI: 10.4155/fmc.10.302  1
2010 Ramakrishnan L, Hess GP. Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. Biochemistry. 49: 7892-901. PMID 20726514 DOI: 10.1021/bi901241g  1
2010 Lewis RW, Mabry J, Polisar JG, Eagen KP, Ganem B, Hess GP. Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. Biochemistry. 49: 4841-51. PMID 20450160 DOI: 10.1021/bi100119t  1
2010 Sivaprakasam K, Pagán OR, Hess GP. Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor. The Journal of Membrane Biology. 233: 1-12. PMID 20049590 DOI: 10.1007/s00232-009-9215-z  1
2009 Fan L, Lewis RW, Hess GP, Ganem B. A new synthesis of caged GABA compounds for studying GABAA receptors. Bioorganic & Medicinal Chemistry Letters. 19: 3932-3. PMID 19364648 DOI: 10.1016/j.bmcl.2009.03.065  1
2007 Shembekar VR, Chen Y, Carpenter BK, Hess GP. Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light. Biochemistry. 46: 5479-84. PMID 17425336 DOI: 10.1021/bi700280e  1
2006 Krivoshein AV, Hess GP. On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor. Biochemistry. 45: 11632-41. PMID 16981722 DOI: 10.1021/bi061207t  1
2005 Ramakrishnan L, Hess GP. Picrotoxin inhibition mechanism of a gamma-aminobutyric acid A receptor investigated by a laser-pulse photolysis technique. Biochemistry. 44: 8523-32. PMID 15938643 DOI: 10.1021/bi0477283  1
2005 Shembekar VR, Chen Y, Carpenter BK, Hess GP. A protecting group for carboxylic acids that can be photolyzed by visible light. Biochemistry. 44: 7107-14. PMID 15882049 DOI: 10.1021/bi047665o  1
2005 Hagen V, Benndorf K, Kaupp UB, Pavlos CM, Xu H, Toscano JP, Hess GP, Gillespie DC, Kim G, Kandler K. Control of Cellular Activity Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules. 155-251. DOI: 10.1002/3527605592.ch4  1
2004 Cui Y, Ulrich H, Hess GP. Selection of 2'-fluoro-modified RNA aptamers for alleviation of cocaine and MK-801 inhibition of the nicotinic acetylcholine receptor. The Journal of Membrane Biology. 202: 137-49. PMID 15798902 DOI: 10.1007/s00232-004-0725-4  1
2004 Cui Y, Rajasethupathy P, Hess GP. Selection of stable RNA molecules that can regulate the channel-opening equilibrium of the membrane-bound gamma-aminobutyric acid receptor. Biochemistry. 43: 16442-9. PMID 15610038 DOI: 10.1021/bi048667b  1
2004 Chen Y, Banerjee A, Hess GP. Mechanism-based discovery of small molecules that prevent noncompetitive inhibition by cocaine and MK-801 mediated by two different sites on the nicotinic acetylcholine receptor. Biochemistry. 43: 10149-56. PMID 15287742 DOI: 10.1021/bi049590u  1
2004 Ramakrishnan L, Hess GP. On the mechanism of a mutated and abnormally functioning gamma-aminobutyric acid (A) receptor linked to epilepsy. Biochemistry. 43: 7534-40. PMID 15182195 DOI: 10.1021/bi036181+  1
2004 Krivoshein AV, Hess GP. Mechanism-based approach to the successful prevention of cocaine inhibition of the neuronal (alpha 3 beta 4) nicotinic acetylcholine receptor. Biochemistry. 43: 481-9. PMID 14717603 DOI: 10.1021/bi034838l  1
2003 Banerjee A, Grewer C, Ramakrishnan L, Jäger J, Gameiro A, Breitinger HG, Gee KR, Carpenter BK, Hess GP. Toward the development of new photolabile protecting groups that can rapidly release bioactive compounds upon photolysis with visible light. The Journal of Organic Chemistry. 68: 8361-7. PMID 14575458 DOI: 10.1021/jo0300643  1
2003 Hess GP, Gameiro AM, Schoenfeld RC, Chen Y, Ulrich H, Nye JA, Sit B, Carroll FI, Ganem B. Reversing the action of noncompetitive inhibitors (MK-801 and cocaine) on a protein (nicotinic acetylcholine receptor)-mediated reaction. Biochemistry. 42: 6106-14. PMID 12755612 DOI: 10.1021/bi020677u  1
2003 Hess GP. Rapid chemical reaction techniques developed for use in investigations of membrane-bound proteins (neurotransmitter receptors). Biophysical Chemistry. 100: 493-506. PMID 12646386 DOI: 10.1016/S0301-4622(02)00301-0  1
2002 Wieboldt R, Ramesh D, Jabri E, Karplus PA, Carpenter BK, Hess GP. Synthesis and characterization of photolabile o-nitrobenzyl derivatives of urea. The Journal of Organic Chemistry. 67: 8827-31. PMID 12467395 DOI: 10.1021/jo0201373  1
2002 Li H, Nowak LM, Gee KR, Hess GP. Mechanism of glutamate receptor-channel function in rat hippocampal neurons investigated using the laser-pulse photolysis (LaPP) technique. Biochemistry. 41: 4753-9. PMID 11939769 DOI: 10.1021/bi0118916  1
2001 Breitinger HG, Geetha N, Hess GP. Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques. Biochemistry. 40: 8419-29. PMID 11444989 DOI: 10.1021/bi0106890  1
2000 Hess GP, Ulrich H, Breitinger HG, Niu L, Gameiro AM, Grewer C, Srivastava S, Ippolito JE, Lee SM, Jayaraman V, Coombs SE. Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801. Proceedings of the National Academy of Sciences of the United States of America. 97: 13895-900. PMID 11095713 DOI: 10.1073/pnas.240459497  1
2000 Breitinger HG, Wieboldt R, Ramesh D, Carpenter BK, Hess GP. Synthesis and characterization of photolabile derivatives of serotonin for chemical kinetic investigations of the serotonin 5-HT(3) receptor. Biochemistry. 39: 5500-8. PMID 10820023 DOI: 10.1021/bi992781q  1
2000 Grewer C, Jäger J, Carpenter BK, Hess GP. A new photolabile precursor of glycine with improved properties: A tool for chemical kinetic investigations of the glycine receptor. Biochemistry. 39: 2063-70. PMID 10684656 DOI: 10.1021/bi9919652  1
2000 Banerjee A, Carpenter BK, Hess GP. Development of new photolabile protecting groups that can rapidly release bioactive compounds on photolysis with visible light American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 41: 885-886.  1
1999 Jayaraman V, Usherwood PN, Hess GP. Inhibition of nicotinic acetylcholine receptor by philanthotoxin-343: kinetic investigations in the microsecond time region using a laser-pulse photolysis technique. Biochemistry. 38: 11406-14. PMID 10471291 DOI: 10.1021/bi991219x  1
1999 Jayaraman V, Thiran S, Hess GP. How fast does the gamma-aminobutyric acid receptor channel open? Kinetic investigations in the microsecond time region using a laser-pulse photolysis technique. Biochemistry. 38: 11372-8. PMID 10471287 DOI: 10.1021/bi990454c  1
1999 Grewer C, Hess GP. On the mechanism of inhibition of the nicotinic acetylcholine receptor by the anticonvulsant MK-801 investigated by laser-pulse photolysis in the microsecond-to-millisecond time region. Biochemistry. 38: 7837-46. PMID 10387024 DOI: 10.1021/bi9827767  1
1999 Gee KR, Niu L, Schaper K, Jayaraman V, Hess GP. Synthesis and photochemistry of a photolabile precursor of N-methyl-D-aspartate (NMDA) that is photolyzed in the microsecond time region and is suitable for chemical kinetic investigations of the NMDA receptor. Biochemistry. 38: 3140-7. PMID 10074369 DOI: 10.1021/bi9826557  1
1998 Ulrich H, Ippolito JE, Pagán OR, Eterović VA, Hann RM, Shi H, Lis JT, Eldefrawi ME, Hess GP. In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 95: 14051-6. PMID 9826651 DOI: 10.1073/pnas.95.24.14051  1
1998 Hess GP, Grewer C. Development and application of caged ligands for neurotransmitter receptors in transient kinetic and neuronal circuit mapping studies. Methods in Enzymology. 291: 443-73. PMID 9661164 DOI: 10.1016/S0076-6879(98)91028-X  1
1998 Gee KR, Carpenter BK, Hess GP. Synthesis, photochemistry, and biological characterization of photolabile protecting groups for carboxylic acids and neurotransmitters. Methods in Enzymology. 291: 30-50. PMID 9661143 DOI: 10.1016/S0076-6879(98)91005-9  1
1998 Hess GP. Laser-pulse photolysis studies of chemical reactions in the brain Proceedings of Spie - the International Society For Optical Engineering. 3273: 56-67. DOI: 10.1117/12.306110  1
1998 Ulrich H, Ippolito F, Pagan OR, Shi H, Lis JT, Hess GP. Cocaine-displaceable rna aptamers bound to the nicotinic acetylcholine receptor Faseb Journal. 12: A1303.  1
1997 Li H, Avery L, Denk W, Hess GP. Identification of chemical synapses in the pharynx of Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 94: 5912-6. PMID 9159174 DOI: 10.1073/pnas.94.11.5912  1
1997 Breitinger HG, Hess GP. Transient kinetic investigations of the inhibition of the 5-ht-4 serotonin receptor by nicotine Faseb Journal. 11: A969.  1
1997 Jayaraman V, Hess GP. Channel-opening kinetics of the y-amino butyric acid (GABA) receptor investigated by rapid chemical kinetic methods Faseb Journal. 11: A969.  1
1996 Hess GP. Determination of the chemical mechanism of neurotransmitter receptor-mediated reactions by rapid chemical kinetic methods. Archives of Physiology and Biochemistry. 104: 752-61. PMID 8980790 DOI: 10.1076/apab.104.6.752.12911  1
1996 Niu L, Vazquez RW, Nagel G, Friedrich T, Bamberg E, Oswald RE, Hess GP. Rapid chemical kinetic techniques for investigations of neurotransmitter receptors expressed in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 93: 12964-8. PMID 8917527 DOI: 10.1073/pnas.93.23.12964  1
1996 Niu L, Wieboldt R, Ramesh D, Carpenter BK, Hess GP. Synthesis and characterization of a caged receptor ligand suitable for chemical kinetic investigations of the glycine receptor in the 3-microseconds time domain. Biochemistry. 35: 8136-42. PMID 8679565 DOI: 10.1021/bi952364n  1
1996 Niu L, Gee KR, Schaper K, Hess GP. Synthesis and photochemical properties of a kainate precursor and activation of kainate and AMPA receptor channels on a microsecond time scale. Biochemistry. 35: 2030-6. PMID 8639688 DOI: 10.1021/bi9516485  1
1996 Niu L, Grewer C, Hess GP. Chemical kinetic investigations of neurotransmitter receptors on a cell Surface in the μs time region Techniques in Protein Chemistry. 7: 139-149. DOI: 10.1016/S1080-8914(96)80018-4  1
1995 Niu L, Abood LG, Hess GP. Cocaine: mechanism of inhibition of a muscle acetylcholine receptor studied by a laser-pulse photolysis technique. Proceedings of the National Academy of Sciences of the United States of America. 92: 12008-12. PMID 8618833 DOI: 10.1073/pnas.92.26.12008  1
1995 Hess GP, Niu L, Wieboldt R. Determination of the chemical mechanism of neurotransmitter receptor-mediated reactions by rapid chemical kinetic methods. Annals of the New York Academy of Sciences. 757: 23-39. PMID 7611678 DOI: 10.1111/j.1749-6632.1995.tb17462.x  1
1995 Gee KR, Niu L, Schaper K, Hess GP. Caged bioactive carboxylates. Synthesis, photolysis studies, and biological characterization of a new caged N-methyl-D-aspartic acid Journal of Organic Chemistry. 60: 4260-4263.  1
1994 Wieboldt R, Ramesh D, Carpenter BK, Hess GP. Synthesis and photochemistry of photolabile derivatives of gamma-aminobutyric acid for chemical kinetic investigations of the gamma-aminobutyric acid receptor in the millisecond time region. Biochemistry. 33: 1526-33. PMID 8312272  1
1994 Wieboldt R, Gee KR, Niu L, Ramesh D, Carpenter BK, Hess GP. Photolabile precursors of glutamate: synthesis, photochemical properties, and activation of glutamate receptors on a microsecond time scale. Proceedings of the National Academy of Sciences of the United States of America. 91: 8752-6. PMID 8090718 DOI: 10.1073/pnas.91.19.8752  1
1994 Walstrom KM, Hess GP. Mechanism for the channel-opening reaction of strychnine-sensitive glycine receptors on cultured embryonic mouse spinal cord cells. Biochemistry. 33: 7718-30. PMID 7516705 DOI: 10.1021/bi00190a027  1
1994 Gee KR, Wieboldt R, Hess GP. Synthesis and photochemistry of a new photolabile derivative of GABA. Neurotransmitter release and receptor activation in the microsecond time region Journal of the American Chemical Society. 116: 8366-8367. DOI: 10.1021/ja00097a054  1
1994 Chen HC, Hess GP. Expression and characteristics of nicotinic receptors in Xenopus oocytes Chinese Journal of Pharmacology and Toxicology. 8: 110-113.  1
1993 Niu L, Hess GP. An acetylcholine receptor regulatory site in BC3H1 cells: characterized by laser-pulse photolysis in the microsecond-to-millisecond time region. Biochemistry. 32: 3831-5. PMID 8471597  1
1993 Hess GP. Determination of the chemical mechanism of neurotransmitter receptor-mediated reactions by rapid chemical kinetic techniques. Biochemistry. 32: 989-1000. PMID 8381026  1
1993 Ramesh D, Wieboldt R, Niu L, Carpenter BK, Hess GP. Photolysis of a protecting group for the carboxyl function of neurotransmitters within 3 microseconds and with product quantum yield of 0.2. Proceedings of the National Academy of Sciences of the United States of America. 90: 11074-8. PMID 7902580 DOI: 10.1073/pnas.90.23.11074  1
1993 Ramesh D, Wieboldt R, Billington AP, Carpenter BK, Hess GP. Photolabile precursors of biological amides: Synthesis and characterization of caged o-nitrobenzyl derivatives of glutamine, asparagine, glycinamide, and γ-aminobutyramide Journal of Organic Chemistry. 58: 4599-4605. DOI: 10.1021/jo00069a021  1
1992 Matsubara N, Billington AP, Hess GP. How fast does an acetylcholine receptor channel open? Laser-pulse photolysis of an inactive precursor of carbamoylcholine in the microsecond time region with BC3H1 cells. Biochemistry. 31: 5507-14. PMID 1610795 DOI: 10.1021/bi00139a012  1
1992 Billington AP, Walstrom KM, Ramesh D, Guzikowski AP, Carpenter BK, Hess GP. Synthesis and photochemistry of photolabile N-glycine derivatives and effects of one on the glycine receptor. Biochemistry. 31: 5500-7. PMID 1377023 DOI: 10.1021/bi00139a011  1
1992 Geetha N, Hess GP. On the mechanism of the gamma-aminobutyric acid receptor in the mammalian (mouse) cerebral cortex. Chemical kinetic investigations with a 10-ms time resolution adapted to measurements of neuronal receptor function in single cells. Biochemistry. 31: 5488-99. PMID 1377022 DOI: 10.1021/bi00139a010  1
1992 Matsubara N, Hess GP. On the mechanism of a mammalian neuronal type nicotinic acetylcholine receptor investigated by a rapid chemical kinetic technique. Detection and characterization of a short-lived, previously unobserved, main receptor form in PC12 cells. Biochemistry. 31: 5477-87. PMID 1377021 DOI: 10.1021/bi00139a009  1
1991 Chandra S, Henderson JE, Morrison GH, Hess GP. Imaging acetylcholine-receptor-induced influx of inorganic ions at single-cell resolution with ion microscopy. Analytical Biochemistry. 197: 284-9. PMID 1785680 DOI: 10.1016/0003-2697(91)90393-8  0.44
1991 Matsubara N, Billington AP, Chen HC, Guzikowski AP, Johnson KW, Ramesh D, Sweet MT, Hess GP. Chemical kinetic investigations of the channel-opening process of neurotransmitter receptors. Advances in Experimental Medicine and Biology. 287: 75-82. PMID 1722073  1
1990 Wilcox M, Viola RW, Johnson KW, Billington AP, Carpenter BK, McCray JA, Guzikowski AP, Hess GP. Synthesis of photolabile "precursors" of amino acid neurotransmitters Journal of Organic Chemistry. 55: 1585-1589.  1
1989 Milburn T, Matsubara N, Billington AP, Udgaonkar JB, Walker JW, Carpenter BK, Webb WW, Marque J, Denk W, McCray JA. Synthesis, photochemistry, and biological activity of a caged photolabile acetylcholine receptor ligand. Biochemistry. 28: 49-55. PMID 2706267  1
1989 Jansen KU, Conroy WG, Claudio T, Fox TD, Fujita N, Hamill O, Lindstrom JM, Luther M, Nelson N, Ryan KA. Expression of the four subunits of the Torpedo californica nicotinic acetylcholine receptor in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 264: 15022-7. PMID 2670931  1
1988 Matsubara N, Hess GP. Application of fast reaction techniques to kinetic measurements of receptor function on cell surfaces. Advances in Experimental Medicine and Biology. 236: 163-72. PMID 2853562  1
1988 Sweet MT, Lindstrom J, Fujita N, Jansen K, Min CK, Claudio T, Nelson N, Fox TD, Hess GP. Chapter 10 Expression of Acetylcholine Receptor Subunits in Saccharomyces cerevisiae (Yeast) Current Topics in Membranes and Transport. 33: 197-218. DOI: 10.1016/S0070-2161(08)60900-4  1
1987 Udgaonkar JB, Hess GP. Acetylcholine receptor: channel-opening kinetics evaluated by rapid chemical kinetic and single-channel current measurements. Biophysical Journal. 52: 873-83. PMID 2447965 DOI: 10.1016/S0006-3495(87)83281-2  1
1987 Udgaonkar JB, Hess GP. Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique. Proceedings of the National Academy of Sciences of the United States of America. 84: 8758-62. PMID 2447583  1
1987 Hess GP, Udgaonkar JB, Olbricht WL. Chemical kinetic measurements of transmembrane processes using rapid reaction techniques: acetylcholine receptor. Annual Review of Biophysics and Biophysical Chemistry. 16: 507-34. PMID 2439099 DOI: 10.1146/annurev.bb.16.060187.002451  1
1987 Udgaonkar JB, Hess GP. Isosteric regulation of the acetylcholine receptor Trends in Pharmacological Sciences. 8: 190-192. DOI: 10.1016/0165-6147(87)90165-9  1
1987 Hess GP, Udgaonkar JB. Voltage-dependent inhibition of the acetylcholine receptor Trends in Pharmacological Sciences. 8: 335. DOI: 10.1016/0165-6147(87)90140-4  1
1986 Karpen JW, Sachs AB, Pasquale EB, Hess GP. Spectrophotometric detection of monovalent cation flux in cells: fluorescence microscope measurement of acetylcholine receptor-mediated ion flux in PC-12 cells. Analytical Biochemistry. 157: 353-9. PMID 3777439 DOI: 10.1016/0003-2697(86)90637-8  1
1986 Walker JW, McCray JA, Hess GP. Photolabile protecting groups for an acetylcholine receptor ligand. Synthesis and photochemistry of a new class of o-nitrobenzyl derivatives and their effects on receptor function. Biochemistry. 25: 1799-805. PMID 3707910  1
1986 Takeyasu K, Shiono S, Udgaonkar JB, Fujita N, Hess GP. Acetylcholine receptor: characterization of the voltage-dependent regulatory (inhibitory) site for acetylcholine in membrane vesicles from Torpedo californica electroplax. Biochemistry. 25: 1770-6. PMID 3707909  1
1986 Fujita N, Sweet MT, Fox TD, Nelson N, Claudio T, Lindstrom JM, Hess GP. Expression of cDNAs for acetylcholine receptor subunits in the yeast cell plasma membrane. Biochemical Society Symposium. 52: 41-56. PMID 3579969  1
1986 Udgaonkar JB, Hess GP. Acetylcholine receptor kinetics: chemical kinetics. The Journal of Membrane Biology. 93: 93-109. PMID 3543374 DOI: 10.1007/BF01870803  1
1986 Fujita N, Nelson N, Fox TD, Claudio T, Lindstrom J, Riezman H, Hess GP. Biosynthesis of the Torpedo californica acetylcholine receptor alpha subunit in yeast. Science (New York, N.Y.). 231: 1284-7. PMID 3511531 DOI: 10.1126/science.3511531  1
1986 Pasquale EB, Udgaonkar JB, Hess GP. Single-channel current recordings of acetylcholine receptors in electroplax isolated from the Electrophorus electricus Main and Sachs' electric organs. The Journal of Membrane Biology. 93: 195-204. PMID 2433452 DOI: 10.1007/BF01870811  1
1986 Huganir RL, Delcour AH, Greengard P, Hess GP. Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature. 321: 774-6. PMID 2423885 DOI: 10.1038/321774a0  1
1986 Delcour AH, Hess GP. Chemical kinetic measurements of the effect of trans- and cis-3,3'-Bis[(trimethylammonio)methyl]azobenzene bromide on acetylcholine receptor mediated ion translocation in Electrophorus electricus and Torpedo californica. Biochemistry. 25: 1793-8. PMID 2423118  1
1986 Karpen JW, Hess GP. Acetylcholine receptor inhibition by d-tubocurarine involves both a competitive and a noncompetitive binding site as determined by stopped-flow measurements of receptor-controlled ion flux in membrane vesicles. Biochemistry. 25: 1786-92. PMID 2423117  1
1986 Karpen JW, Hess GP. Cocaine, phencyclidine, and procaine inhibition of the acetylcholine receptor: characterization of the binding site by stopped-flow measurements of receptor-controlled ion flux in membrane vesicles. Biochemistry. 25: 1777-85. PMID 2423116  1
1985 Cash DJ, Aoshima H, Pasquale EB, Hess GP. Acetylcholine-receptor-mediated ion fluxes in Electrophorus electricus and Torpedo california membrane vesicles. Reviews of Physiology, Biochemistry and Pharmacology. 102: 73-117. PMID 2412273  1
1985 Karpen JW, Hess GP. D-tubocurarine inhibition of the acetylcholine receptor: Stopped-flow measurements of receptor-mediated ion flux in membrane vesicles Federation Proceedings. 44: NO. 475.  1
1984 Cash DJ, Hess GP. Acetylcholine receptor: dynamic properties. Biophysical Journal. 45: 8-10. PMID 19431574  1
1984 Shiono S, Takeyasu K, Udgaonkar JB, Delcour AH, Fujita N, Hess GP. Regulatory properties of acetylcholine receptor: evidence for two different inhibitory sites, one for acetylcholine and the other for a noncompetitive inhibitor of receptor function (procaine). Biochemistry. 23: 6889-93. PMID 6529587  1
1984 Hess GP, Kolb HA, Läuger P, Schoffeniels E, Schwarze W. Acetylcholine receptor (from Electrophorus electricus): a comparison of single-channel current recordings and chemical kinetic measurements. Proceedings of the National Academy of Sciences of the United States of America. 81: 5281-5. PMID 6089188  1
1983 Takeyasu K, Udgaonkar JB, Hess GP. Acetylcholine receptor: evidence for a voltage-dependent regulatory site for acetylcholine. Chemical kinetic measurements in membrane vesicles using a voltage clamp. Biochemistry. 22: 5973-8. PMID 6661421  1
1983 Pasquale EB, Takeyasu K, Udgaonkar JB, Cash DJ, Severski MC, Hess GP. Acetylcholine receptor: evidence for a regulatory binding site in investigations of suberyldicholine-induced transmembrane ion flux in Electrophorus electricus membrane vesicles. Biochemistry. 22: 5967-73. PMID 6661420  1
1983 Sachs AB, Leprince P, Karpen JW, Pasquale EB, Abood LG, Hess GP. Phencyclidine inhibition of the acetylcholine receptor: measurement of cation flux in a sympathetic neuronal cell line using 22Na+ and spectroscopic detection of Cs+. Archives of Biochemistry and Biophysics. 225: 500-4. PMID 6625597 DOI: 10.1016/0003-9861(83)90059-0  1
1983 Hess GP, Cash DJ, Aoshima H. Acetylcholine receptor-controlled ion translocation: chemical kinetic investigations of the mechanism. Annual Review of Biophysics and Bioengineering. 12: 443-73. PMID 6307118 DOI: 10.1146/annurev.bb.12.060183.002303  1
1983 Karpen JW, Sachs AB, Cash DJ, Pasquale EB, Hess GP. Direct spectrophotometric detection of cation flux in membrane vesicles: stopped-flow measurements of acetylcholine-receptor-mediated ion flux. Analytical Biochemistry. 135: 83-94. PMID 6230951 DOI: 10.1016/0003-2697(83)90734-0  1
1982 Sachs AB, Lenchitz B, Noble RL, Hess GP. A convenient large-scale method for the isolation of membrane vesicles permeable to a specific inorganic ion: isolation and characterization of functional acetylcholine receptor-containing vesicles from the electric organ of Electrophorus electricus. Analytical Biochemistry. 124: 185-90. PMID 7125221 DOI: 10.1016/0003-2697(82)90236-6  1
1982 Karpen JW, Aoshima H, Abood LG, Hess GP. Cocaine and phencyclidine inhibition of the acetylcholine receptor: analysis of the mechanisms of action based on measurements of ion flux in the millisecond-to-minute time region. Proceedings of the National Academy of Sciences of the United States of America. 79: 2509-13. PMID 6953408  1
1982 Hess GP, Pasquale EB, Walker JW, McNamee MG. Comparison of acetylcholine receptor-controlled cation flux in membrane vesicles from Torpedo californica and Electrophorus electricus: chemical kinetic measurements in the millisecond region. Proceedings of the National Academy of Sciences of the United States of America. 79: 963-7. PMID 6951180  1
1982 Hess GP, Pasquale EB, Karpen JW, Sachs AB, Takeyasu K, Cash DJ. Acetylcholine receptor-controlled ion translocation. A comparison of the effects of suberyldicholine, carbamoylcholine, and acetylcholine. Biochemical and Biophysical Research Communications. 107: 1583-8. PMID 6291537 DOI: 10.1016/S0006-291X(82)80181-2  1
1982 Delcour A, Cash DJ, Erlanger BF, Hess GP. Separation of cis- and trans-3,3′-bis(trimethylammoniomethyl)azobenzene salts (Bis Q salts) by reversed-phase high-performance liquid chromatography Journal of Chromatography A. 248: 461-468. DOI: 10.1016/S0021-9673(00)85058-X  1
1982 Hess GP. Can the acetylcholine receptor control the transfer of signals between cells of the nervous system? Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 363: 899.  1
1981 Ramseyer GO, Morrison GH, Aoshima H, Hess GP. Vidicon flame emission spectroscopy of Li+, Na+, and K+ fluxes mediated by acetylcholine receptor in Electrophorus electricus membrane vesicles. Analytical Biochemistry. 115: 34-41. PMID 7304950 DOI: 10.1016/0003-2697(81)90518-2  1
1981 Leprince P, Noble RL, Hess GP. Comparison of the interactions of a specific neurotoxin (alpha-bungarotoxin) with the acetylcholine receptor in Torpedo californica and Electrophorus electricus membrane preparations. Biochemistry. 20: 5565-70. PMID 7295693  1
1981 Aoshima H, Cash DJ, Hess GP. Mechanism of inactivation (desensitization) of acetylcholine receptor. Investigations by fast reaction techniques with membrane vesicles. Biochemistry. 20: 3467-74. PMID 7260051  1
1981 Walker JW, McNamee MG, Pasquale E, Cash DJ, Hess GP. Acetylcholine receptor inactivation in Torpedo californica electroplax membrane vesicles. Detection of two processes in the millisecond and second time regions. Biochemical and Biophysical Research Communications. 100: 86-90. PMID 7259763 DOI: 10.1016/S0006-291X(81)80066-6  1
1981 Cash DJ, Hess GP. Quenched flow technique with plasma membrane vesicles: acetylcholine receptor-mediated transmembrane ion flux. Analytical Biochemistry. 112: 39-51. PMID 7258627 DOI: 10.1016/0003-2697(81)90257-8  1
1981 Hess GP, Aoshima H, Cash DJ, Lenchitz B. Specific reaction rate of acetylcholine receptor-controlled ion translocation: a comparison of measurements with membrane vesicles and with muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 1361-5. PMID 6940163  1
1981 Cash DJ, Aoshima H, Hess GP. Acetylcholine-induced cation translocation across cell membranes and inactivation of the acetylcholine receptor: chemical kinetic measurements in the millisecond time region. Proceedings of the National Academy of Sciences of the United States of America. 78: 3318-22. PMID 6267581  1
1981 Kim PS, Hess GP. Acetylcholine receptor-controlled ion flux in electroplax membrane vesicles: identification and characterization of membrane properties that affect ion flux measurements. The Journal of Membrane Biology. 58: 203-11. PMID 6163857 DOI: 10.1007/BF01870906  1
1980 Hess GP, Cash DJ, Aoshima H. Kinetic mechanism of acetylcholine receptor-controlled ion flux: Flow quench kinetic measurements of acetylcholine-induced flux in membrane vesicles. Neurochemistry International. 2: 233-42. PMID 20487789 DOI: 10.1016/0197-0186(80)90030-3  1
1980 Epstein N, Hess GP, Kim PS, Noble RL. Inactivation (desensitization) of the acetylcholine receptor in Electrophorus electricus membrane vesicles by carbamylcholine: comparison between ion flux and alpha-bungarotoxin binding. The Journal of Membrane Biology. 56: 133-7. PMID 7441723 DOI: 10.1007/BF01875964  1
1980 Aoshima H, Cash DJ, Hess GP. Acetylcholine receptor-controlled ion flux in electroplax membrane vesicles: a minimal mechanism based on rate measurements in the millisecond to minute time region. Biochemical and Biophysical Research Communications. 92: 896-904. PMID 7362613 DOI: 10.1016/0006-291X(80)90787-1  1
1980 Cash DJ, Hess GP. Molecular mechanism of acetylcholine receptor-controlled ion translocation across cell membranes. Proceedings of the National Academy of Sciences of the United States of America. 77: 842-6. PMID 6928684  1
1980 Cash DJ, Aoshima H, Hess GP. Acetylcholine-induced receptor-controlled ion flux investigated by flow quench techniques. Biochemical and Biophysical Research Communications. 95: 1010-6. PMID 6251825  1
1979 Hess GP, Cash DJ, Aoshima H. Acetylcholine receptor-controlled ion fluxes in membrane vesicles investigated by fast reaction techniques. Nature. 282: 329-31. PMID 503209  1
1979 Goto S, Hess GP. Fluorescence studies on the interaction of dansyl-L-arginine with trypsin and trypsinogen. Journal of Biochemistry. 85: 961-5. PMID 457637  1
1979 Noble RL, Cooper MJ, Hess GP. Comparison of Bungarus caeruleus venom with the venom from which a putative cholinergic ionophore marker was isolated. International Journal of Peptide and Protein Research. 13: 142-5. PMID 429091  1
1979 Goto S, Hess GP. Presteady state kinetics of trypsin-catalyzed hydrolyses of dansyl-arginine derivatives. Journal of Biochemistry. 86: 619-25. PMID 41834  1
1979 Noble RL, Epstein N, Hess GP. Desensitization of the acetylcholine receptor in Torpedo californica and Electrophorus electricus membrane vesicles by carbamoylcholine: Comparison between ion flux and α-bungarotoxin binding Federation Proceedings. 38: No. 1495.  1
1978 Rübsamen H, Eldefrawi AT, Eldefrawi ME, Hess GP. Characterization of calcium-binding sites of the purified acetylcholine receptor and identification of the calcium-binding subunit. Biochemistry. 17: 3818-25. PMID 698199  0.44
1978 Hess GP, Lipkowitz S, Struve GE. Acetylcholine-receptor-mediated ion flux in electroplax membrane microsacs (vesicles): change in mechanism produced by asymmetrical distribution of sodium and potassium ions. Proceedings of the National Academy of Sciences of the United States of America. 75: 1703-7. PMID 273901  1
1977 Kohanski RA, Andrews JP, Wins P, Eldefrawi ME, Hess GP. A simple quantitative assay of 125I-labeled alpha-bungarotoxin binding to soluble and membrane-bound acetylcholine receptor protein. Analytical Biochemistry. 80: 531-9. PMID 889090 DOI: 10.1016/0003-2697(77)90676-5  1
1977 Bulger JE, Fu JL, Hindy EF, Silberstein RL, Hess GP. Allosteric interactions between the membrane-bound acetylcholine receptor and chemical mediators. Kinetic studies. Biochemistry. 16: 684-92. PMID 836808  1
1977 Fu JL, Donner DB, Moore DE, Hess GP. Allosteric interactions between the membrane-bound acetylcholine receptor and chemical mediators: equilibrium measurements. Biochemistry. 16: 678-84. PMID 836807  1
1977 Hess GP, Andrews JP. Functional acetylcholine receptor--electroplax membrane microsacs (vesicles): purification and characterization. Proceedings of the National Academy of Sciences of the United States of America. 74: 482-6. PMID 265515  1
1977 Andrews JP, Hess GP. Purification of acetylcholine receptor electroplax membrane vesicles Federation Proceedings. 36: No.2512.  1
1976 Hess GP, Andrews JP, Struve GE. Apparent cooperative effects in acetylcholine receptor-mediated ion flux electroplax membrane preparations. Biochemical and Biophysical Research Communications. 69: 830-7. PMID 1267819 DOI: 10.1016/0006-291X(76)90950-5  1
1976 Donner DB, Fu JJ, Hess GP. Equilibrium dialysis of the membrane-bound acetylcholine receptor: a simple method to avoid common errors. Analytical Biochemistry. 75: 454-63. PMID 984406 DOI: 10.1016/0003-2697(76)90100-7  1
1976 Rübsamen H, Hess GP, Eldefrawi AT, Eldefrawi ME. Interaction between calcium and ligand-binding sites of the purified acetylcholine receptor studied by use of a fluorescent lanthanide. Biochemical and Biophysical Research Communications. 68: 56-63. PMID 942851 DOI: 10.1016/0006-291X(76)90009-7  1
1976 Eldefrawi AT, Eldefrawi ME. Identification of a calcium-binding subunit of the acetylcholine receptor. Biochemical and Biophysical Research Communications. 70: 1020-7. PMID 938522 DOI: 10.1016/0013-4694(76)90219-4  1
1976 Andrews JP, Struve GE, Hess GP. Acetylcholine receptor mediated ion flux in electroplax preparation Biophysical Journal. 16: 213a.  1
1975 Moore DE, Hess GP. Acetylcholinesterase-catalyzed hydrolysis of an amide. Biochemistry. 14: 2386-9. PMID 1169963  1
1975 Hess GP, Bulger JE, Fu JJ, Hindy EF, Silberstein RJ. Allosteric interactions of the membrane-bound acetylcholine reception: kinetic studies with alpha-bungarotoxin. Biochemical and Biophysical Research Communications. 64: 1018-27. PMID 1147955 DOI: 10.1016/0006-291X(75)90149-7  1
1975 Holler E, Rupley JA, Hess GP. Productive and unproductive lysozyme-chitosaccharide complexes. Kinetic investigations. Biochemistry. 14: 2377-85. PMID 1138867  1
1975 Holler E, Rupley JA, Hess GP. Productive and unproductive lysozyme-chitosaccharide complexes. Equilibrium measurements. Biochemistry. 14: 1088-94. PMID 1125174  1
1975 Hess GP, Andrews JP, Struve GE, Goombs SE. Acetylcholine-receptor-mediated ion flux in electroplax membrane preparations. Proceedings of the National Academy of Sciences of the United States of America. 72: 4371-5. PMID 1060114  1
1975 Banerjee SK, Holler E, Hess GP, Rupley JA. Reaction of N-acetylglucosamine oligosaccharides with lysozyme. Temperature, pH, and solvent deuterium isotope effects; equilbrium, steady state, and pre-steady state measurements*. The Journal of Biological Chemistry. 250: 4355-67. PMID 236317  1
1974 Holler E, Rupley JA, Hess GP. The determination of the dissociation constants of productive and unproductive lysozyme substrate complexes. Febs Letters. 40: 25-8. PMID 4854710  1
1974 Davis LA, Hess GP. Determination of dissociation constants of crystalline-alpha-chymotrypsin complexes. Journal of Molecular Biology. 82: 27-33. PMID 4818483 DOI: 10.1016/0022-2836(74)90572-5  1
1974 Koehler KA, Hess GP. [A new, specific and reversible bifunctional alkylborinic acid inhibitor of acetylcholinesterase]. Biochemistry. 13: 5345-50. PMID 4433524  1
1974 Fu JL, Donner DB, Hess GP. Half-of-the-sites reactivity of the membrane-bound Electrophorus electricus acetylcholine receptor. Biochemical and Biophysical Research Communications. 60: 1072-80. PMID 4429562 DOI: 10.1016/0006-291X(74)90422-7  1
1974 Davis LA, Schejter A, Hess GP. Alkaline isomerization of oxidized cytochrome c. Equilibrium and kinetic measurements. The Journal of Biological Chemistry. 249: 2624-32. PMID 4362690  1
1973 Bulger JE, Hess GP. Evidence for separate initiation and inhibitory sites in the regulation of membrane potential of electroplax. I. Kinetic studies with alpha-bungarotoxin. Biochemical and Biophysical Research Communications. 54: 677-84. PMID 4756794  0.88
1972 Wright CS, Hess GP, Blow DM. Structure of crystalline methyl-chymotrypsin. Journal of Molecular Biology. 63: 295-303. PMID 4634509 DOI: 10.1016/0022-2836(72)90376-2  1
1972 Henderson R, Wright CS, Hess GP, Blow DM. -Chymotrypsin: what can we learn about catalysis from x-ray diffraction? Cold Spring Harbor Symposia On Quantitative Biology. 36: 63-70. PMID 4508173  1
1971 McConn J, Ku E, Himoe A, Brandt KG, Hess GP. Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. V. Determination of pre-steady state kinetic parameters for specific substrate esters by stopped flow techniques. The Journal of Biological Chemistry. 246: 2918-25. PMID 5554299  1
1971 Hess GP, Rupley JA. Structure and function of proteins. Annual Review of Biochemistry. 40: 1013-44. PMID 4333476 DOI: 10.1146/annurev.bi.40.070171.005053  0.36
1970 Holler E, Rupley JA, Hess GP. Kinetics of lysozyme-substrate interactions. Biochemical and Biophysical Research Communications. 40: 166-70. PMID 5456953  1
1970 Fresco JR, Hess GP, Russell RL, Brown JC, Dube S, Wootton JF, Spudich JA, Steitz TA. Shapiro's defection. Science (New York, N.Y.). 167: 1668. PMID 5416525 DOI: 10.1126/science.167.3926.1668  0.32
1970 Hess GP, McConn J, Ku E, McConkey G. Studies of the activity of chymotrypsin. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 257: 89-104. PMID 4399052  0.52
1969 Himoe A, Brandt KG, DeSa RJ, Hess GP. Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. IV. Pre-steady state kinetic approaches to the investigation of the catalytic hydrolysis of esters. The Journal of Biological Chemistry. 244: 3483-93. PMID 5798622  1
1969 Rossi GL, Holler E, Kumar S, Rupley JA, Hess GP. Labelling of the catalytic site of lysozyme. Biochemical and Biophysical Research Communications. 37: 757-66. PMID 5362279  1
1969 McConn J, Fasman GD, Hess GP. Conformation of the high pH form of chymotrypsin. Journal of Molecular Biology. 39: 551-62. PMID 5357213  0.52
1969 Holler E, Rupley JA, Hess GP. Kinetics of lysozyme-substrate interactions. Biochemical and Biophysical Research Communications. 37: 423-9. PMID 5349281  1
1968 McConn J, Ku E, Odell C, Czerlinski G, Hess GP. Conformation and activity of chymotrypsin: the pH-dependent, substrate-induced proton uptake. Science (New York, N.Y.). 161: 274-6. PMID 5657332  0.52
1967 Himoe A, Hess GP. Kinetic investigations of the alcohol release steps in the chymotrypsin-catalyzed hydrolysis of specific substrate esters. Biochemical and Biophysical Research Communications. 27: 494-9. PMID 6052480  0.72
1967 Brandt KG, Himoe A, Hess GP. Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. 3. Determination of individual rate constants and enzyme-substrate binding constants for specific amide and ester substrates. The Journal of Biological Chemistry. 242: 3973-82. PMID 6037555  1
1967 Himoe A, Brandt KG, Hess GP. Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. II. Characterization of the spectral changes of the enzyme at 290 m-mu and determination of over-all enzyme-substrate dissociation constants. The Journal of Biological Chemistry. 242: 3963-72. PMID 6037554  1
1967 Himoe A, Parks PC, Hess GP. Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. I. The pH dependence of the catalytic hydrolysis of N-acetyl-L-tryptophanamide by three forms of the enzyme at alkaline pH. The Journal of Biological Chemistry. 242: 919-29. PMID 6020443  0.72
1966 Himoe A, Hess GP. On the elucidation of the pH dependence of chymotrypsin catalyzed reactions at alkaline pH. Biochemical and Biophysical Research Communications. 23: 234-9. PMID 5960855  0.72
1966 Brandt KG, Parks PC, Czerlinski GH, Hess GP. On the elucidation of the pH dependence of the oxidation-reduction potential of cytochrome c at alkaline pH. The Journal of Biological Chemistry. 241: 4180-5. PMID 4958912  1
1965 LENARD J, JOHNSON SL, HYMAN RW, HESS GP. A CONTINUOUS, AUTOMATIC METHOD FOR THE STUDY OF RATE OF HYDROLYSIS OF PEPTIDES AND AMIDES. Analytical Biochemistry. 11: 30-41. PMID 14328643  1
1965 MOON AY, MERCOUROFF J, HESS GP. CHARACTERIZATION OF A REVERSIBLY FORMED ENZYME COMPLEX IN THE REACTION OF CHYMOTRYPSIN WITH DIISOPROPYL FLUOROPHOSPHATE. The Journal of Biological Chemistry. 240: 717-21. PMID 14275126  1
1965 Moon AY, Sturtevant JM, Hess GP. Kinetics of the reaction of alpha-chymotrypsin with diisopropyl fluorophosphate, with measurements of hydrogen ion release, enzyme inhibition, and spectral changes of enzyme at 290 mu. The Journal of Biological Chemistry. 240: 4204-12. PMID 5845823  1
1963 MERCOUROFF J, HESS GP. Interpretation of the ultraviolet spectrum of trans-cinnamoyl-alpha-chymotrypsin. Biochemical and Biophysical Research Communications. 11: 283-7. PMID 13934951  0.12
1961 NELSON WL, CIACCIO EI, HESS GP. A rapid method for the quantitative assay of proteolytic enzymes. Analytical Biochemistry. 2: 39-44. PMID 13728317  1
1958 WOOTTON JF, HESS GP. Studies of the enzymically active material in acetyltrypsin autolysates. Biochimica Et Biophysica Acta. 29: 435-7. PMID 13572368  0.32
1956 Sheehan JC, Goodman M, Hess GP. Peptide derivatives containing hydroxyamino acids Journal of the American Chemical Society. 78: 1367-1369. DOI: 10.1021/ja01588a029  1
1955 Sheehan JC, Hess GP. A New Method of Forming Peptide Bonds Journal of the American Chemical Society. 77: 1067-1068. DOI: 10.1021/ja01609a099  1
1952 CARPENTER FH, HESS GP, LI CH. Distribution studies on partial peptic hydrolysates of adrenocorticotropic hormone. The Journal of Biological Chemistry. 197: 7-16. PMID 12981028  1
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