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Howard S Fox - Publications

Affiliations: 
1990- Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2008- University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Neuroscience Biology, Cell Biology, Immunology
Website:
https://www.unmc.edu/pharmacology/faculty/primary-faculty/fox/fox-bio.html

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu X, Niu M, Lamberty BG, Emanuel K, Ramachandran S, Trease AJ, Tabassum M, Lifson JD, Fox HS. Microglia and macrophages alterations in the CNS during acute SIV infection: A single-cell analysis in rhesus macaques. Plos Pathogens. 20: e1012168. PMID 39283947 DOI: 10.1371/journal.ppat.1012168  0.353
2024 Matt SM, Nolan R, Manikandan S, Agarwal Y, Channer B, Oteju O, Daniali M, Canagarajah JA, LuPone T, Mompho K, Runner K, Nickoloff-Bybel E, Li B, Niu M, Schlachetzki JCM, ... Fox HS, et al. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. Biorxiv : the Preprint Server For Biology. PMID 38915663 DOI: 10.1101/2024.06.09.598137  0.736
2024 Xu X, Niu M, Lamberty BG, Emanuel K, Trease AJ, Tabassum M, Lifson JD, Fox HS. Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 38617282 DOI: 10.1101/2024.04.04.588047  0.353
2024 Caocci M, Niu M, Fox HS, Burdo TH. HIV Infection Drives Foam Cell Formation via NLRP3 Inflammasome Activation. International Journal of Molecular Sciences. 25. PMID 38397063 DOI: 10.3390/ijms25042367  0.319
2022 Fox HS, Niu M, Morsey BM, Lamberty BG, Emanuel K, Periyasamy P, Callen S, Acharya A, Kubik G, Eudy J, Guda C, Dyavar SR, Fletcher CV, Byrareddy SN, Buch S. Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection. Frontiers in Immunology. 13: 1012884. PMID 36466814 DOI: 10.3389/fimmu.2022.1012884  0.3
2022 Trease AJ, Niu M, Morsey B, Guda C, Byrareddy SN, Buch S, Fox HS. Antiretroviral therapy restores the homeostatic state of microglia in SIV-infected rhesus macaques. Journal of Leukocyte Biology. PMID 35686500 DOI: 10.1002/JLB.3HI0422-635R  0.309
2022 Grabowska K, Macur K, Zieschang S, Zaman L, Haverland N, Schissel A, Morsey B, Fox HS, Ciborowski P. HIV-1 and methamphetamine alter galectins -1, -3, and -9 in human monocyte-derived macrophages. Journal of Neurovirology. PMID 35175539 DOI: 10.1007/s13365-021-01025-4  0.346
2020 Niu M, Morsey B, Lamberty BG, Emanuel K, Yu F, León-Rivera R, Berman JW, Gaskill PJ, Matt SM, Ciborowski PS, Fox HS. Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis. Viruses. 12. PMID 33198269 DOI: 10.3390/v12111297  0.766
2020 Avedissian SN, Dyavar SR, Fox HS, Fletcher CV. Pharmacologic approaches to HIV-associated neurocognitive disorders. Current Opinion in Pharmacology. 54: 102-108. PMID 33049585 DOI: 10.1016/j.coph.2020.09.003  0.304
2020 León-Rivera R, Morsey B, Niu M, Fox HS, Berman JW. Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities. Mbio. 11. PMID 32723919 DOI: 10.1128/Mbio.01037-20  0.615
2019 Zhang J, Fox H, Xiong H. Severer nodular lesion in white matter than in gray matter in simian immunodeficiency virus-infected monkey, but not closely correlated with viral infection. Journal of Biomedical Research. 1-9. PMID 32525497 DOI: 10.7555/Jbr.33.20180047  0.376
2019 Winston A, Antinori A, Cinque P, Fox HS, Gisslen M, Henrich TJ, Letendre S, Persaud D, Price RW, Spudich S. Defining cerebrospinal fluid HIV RNA escape: editorial review AIDS. Aids (London, England). 33: S107-S111. PMID 31790376 DOI: 10.1097/Qad.0000000000002252  0.339
2019 Pawlak K, Lech K, Vei A, Burch S, Zieschang S, Jaquet S, Yu F, Harwood E, Morsey B, Fox HS, Ciborowski P. Secreted Metabolome of Human Macrophages Exposed to Methamphetamine. Analytical Chemistry. PMID 31265257 DOI: 10.1021/Acs.Analchem.9B01952  0.307
2018 Lew BJ, McDermott TJ, Wiesman AI, O'Neill J, Mills MS, Robertson KR, Fox HS, Swindells S, Wilson TW. Neural dynamics of selective attention deficits in HIV-associated neurocognitive disorder. Neurology. PMID 30333162 DOI: 10.1212/Wnl.0000000000006504  0.328
2018 McMillan J, Szlachetka A, Zhou T, Morsey B, Lamberty B, Callen S, Gautam N, Alnouti Y, Edagwa B, Gendelman HE, Fox HS. Pharmacokinetic testing of a first generation cabotegravir prodrug in rhesus macaques. Aids (London, England). PMID 30289818 DOI: 10.1097/Qad.0000000000002032  0.315
2018 Spooner RK, Wiesman AI, Mills MS, O'Neill J, Robertson KR, Fox HS, Swindells S, Wilson TW. Aberrant oscillatory dynamics during somatosensory processing in HIV-infected adults. Neuroimage. Clinical. 20: 85-91. PMID 30094159 DOI: 10.1016/J.Nicl.2018.07.009  0.4
2018 Wiesman AI, O'Neill J, Mills MS, Robertson KR, Fox HS, Swindells S, Wilson TW. Aberrant occipital dynamics differentiate HIV-infected patients with and without cognitive impairment. Brain : a Journal of Neurology. PMID 29672678 DOI: 10.1093/Brain/Awy097  0.397
2018 Kevadiya BD, Woldstad C, Ottemann BM, Dash P, Sajja BR, Lamberty B, Morsey B, Kocher T, Dutta R, Bade AN, Liu Y, Callen SE, Fox HS, Byrareddy SN, McMillan JM, et al. Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution. Theranostics. 8: 256-276. PMID 29290806 DOI: 10.7150/Thno.22764  0.301
2017 Bortell N, Basova L, Najera JA, Morsey B, Fox HS, Marcondes MCG. Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 29280055 DOI: 10.1007/S11481-017-9772-3  0.427
2017 Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, et al. Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles. Biomaterials. 151: 53-65. PMID 29059541 DOI: 10.1016/J.Biomaterials.2017.10.023  0.379
2017 Stauch KL, Emanuel K, Lamberty BG, Morsey B, Fox HS. Central nervous system-penetrating antiretrovirals impair energetic reserve in striatal nerve terminals. Journal of Neurovirology. PMID 28895059 DOI: 10.1007/S13365-017-0573-5  0.336
2017 Bortell N, Flynn C, Conti B, Fox HS, Marcondes MCG. Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points. Mediators of Inflammation. 2017: 7582437. PMID 28811681 DOI: 10.1155/2017/7582437  0.392
2017 Ubaida-Mohien C, Lamberty B, Dickens AM, Mielke MM, Marcotte T, Sacktor N, Grant I, Letendre S, Franklin D, Cibrowski P, Tharakan R, McArthur JC, Fox H, Haughey NJ. Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients. Aids (London, England). 31: 1365-1378. PMID 28574961 DOI: 10.1097/Qad.0000000000001503  0.352
2017 Christensen B, Qin Z, Byrd DA, Yu F, Morgello S, Gelman BB, Moore DJ, Grant I, Singer EJ, Fox H, Baccaglini L. Measures of Physical and Mental Independence among HIV-positive Individuals: Impact of Substance Use Disorder. Aids Research and Human Retroviruses. PMID 28288515 DOI: 10.1089/Aid.2016.0269  0.369
2017 Hu G, Liao K, Yang L, Pendyala G, Kook Y, Fox HS, Buch S. Tat-Mediated Induction of miRs-34a & -138 Promotes Astrocytic Activation via Downregulation of SIRT1: Implications for Aging in HAND. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 28236278 DOI: 10.1007/S11481-017-9730-0  0.374
2017 Wilson TW, Proskovec AL, Heinrichs-Graham E, O'Neill J, Robertson KR, Fox HS, Swindells S. Aberrant Neuronal Dynamics during Working Memory Operations in the Aging HIV-Infected Brain. Scientific Reports. 7: 41568. PMID 28155864 DOI: 10.1038/Srep41568  0.319
2017 Fox H. E-104 Extracellular vesicle microRNA leads to neurotoxicity in SIV infection Jaids Journal of Acquired Immune Deficiency Syndromes. 74: 52. DOI: 10.1097/01.Qai.0000513847.10198.Dd  0.313
2016 Hu G, Yang L, Cai Y, Niu F, Mezzacappa F, Callen S, Fox HS, Buch S. Emerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications. Cell Death & Disease. 7: e2481. PMID 27882942 DOI: 10.1038/Cddis.2016.336  0.309
2016 Najera JA, Bustamante EA, Bortell N, Morsey B, Fox HS, Ravasi T, Marcondes MC. Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets. Bmc Immunology. 17: 7. PMID 27107567 DOI: 10.1186/S12865-016-0145-0  0.43
2016 Villeneuve LM, Purnell PR, Stauch KL, Callen SE, Buch SJ, Fox HS. HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution. Journal of Neurovirology. PMID 26843384 DOI: 10.1007/S13365-016-0424-9  0.401
2016 Ciborowski P, Fox HS. Proteomics and HIV. Proteomics. Clinical Applications. 10: 109. PMID 26836751 DOI: 10.1002/Prca.201670023  0.362
2016 Haverland NA, Villeneuve LM, Ciborowski P, Fox HS. The Proteomic Characterization of Plasma or Serum from HIV-Infected Patients. Methods in Molecular Biology (Clifton, N.J.). 1354: 293-310. PMID 26714720 DOI: 10.1007/978-1-4939-3046-3_20  0.381
2015 Pendyala G, Periyasamy P, Callen S, Fox HS, Lisco SJ, Buch SJ. Chronic SIV and morphine treatment increases heat shock protein 5 expression at the synapse. Journal of Neurovirology. 21: 592-8. PMID 26037114 DOI: 10.1007/S13365-015-0356-9  0.374
2015 Wilson TW, Heinrichs-Graham E, Becker KM, Aloi J, Robertson KR, Sandkovsky U, White ML, O'Neill J, Knott NL, Fox HS, Swindells S. Multimodal neuroimaging evidence of alterations in cortical structure and function in HIV-infected older adults. Human Brain Mapping. 36: 897-910. PMID 25376125 DOI: 10.1002/Hbm.22674  0.411
2015 Marcondes MC, Morsey B, Emanuel K, Lamberty BG, Flynn CT, Fox HS. CD8+ T cells maintain suppression of simian immunodeficiency virus in the central nervous system. The Journal of Infectious Diseases. 211: 40-4. PMID 25035516 DOI: 10.1093/Infdis/Jiu401  0.403
2014 Marcondes MC, Ojakian R, Bortell N, Flynn C, Conti B, Fox HS. Osteopontin expression in the brain triggers localized inflammation and cell death when immune cells are activated by pertussis toxin. Mediators of Inflammation. 2014: 358218. PMID 25525298 DOI: 10.1155/2014/358218  0.316
2014 Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE. TLR signaling controls lethal encephalitis in WNV-infected brain. Brain Research. 1574: 84-95. PMID 24928618 DOI: 10.1016/J.Brainres.2014.05.049  0.379
2014 Fox HS. The 20th scientific conference of the Society on NeuroImmune Pharmacology. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 1-2. PMID 24573530 DOI: 10.1007/S11481-014-9537-1  0.313
2014 Haverland NA, Fox HS, Ciborowski P. Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages. Journal of Proteome Research. 13: 2109-19. PMID 24564501 DOI: 10.1021/pr4012602  0.307
2013 Wilson TW, Fox HS, Robertson KR, Sandkovsky U, O'Neill J, Heinrichs-Graham E, Knott NL, Swindells S. Abnormal MEG oscillatory activity during visual processing in the prefrontal cortices and frontal eye-fields of the aging HIV brain. Plos One. 8: e66241. PMID 23840428 DOI: 10.1371/Journal.Pone.0066241  0.4
2013 Wilson TW, Heinrichs-Graham E, Robertson KR, Sandkovsky U, O'Neill J, Knott NL, Fox HS, Swindells S. Functional brain abnormalities during finger-tapping in HIV-infected older adults: a magnetoencephalography study. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 965-74. PMID 23749418 DOI: 10.1007/S11481-013-9477-1  0.376
2013 Marcondes MC, Spina C, Bustamante E, Fox H. Increased toll-like receptor signaling pathways characterize CD8+ cells in rapidly progressive SIV infection. Biomed Research International. 2013: 796014. PMID 23484159 DOI: 10.1155/2013/796014  0.411
2013 Gelman BB, Lisinicchia JG, Morgello S, Masliah E, Commins D, Achim CL, Fox HS, Kolson DL, Grant I, Singer E, Yiannoutsos CT, Sherman S, Gensler G, Moore DJ, Chen T, et al. Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort. Journal of Acquired Immune Deficiency Syndromes (1999). 62: 487-95. PMID 23242157 DOI: 10.1097/Qai.0B013E31827F1Bdb  0.373
2012 Harms R, Morsey B, Boyer CW, Fox HS, Sarvetnick N. Methamphetamine administration targets multiple immune subsets and induces phenotypic alterations suggestive of immunosuppression. Plos One. 7: e49897. PMID 23227154 DOI: 10.1371/Journal.Pone.0049897  0.302
2012 Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, et al. The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. Plos One. 7: e46178. PMID 23049970 DOI: 10.1371/Journal.Pone.0046178  0.434
2012 Hu G, Yao H, Chaudhuri AD, Duan M, Yelamanchili SV, Wen H, Cheney PD, Fox HS, Buch S. Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated neuronal dysfunction. Cell Death & Disease. 3: e381. PMID 22932723 DOI: 10.1038/Cddis.2012.114  0.385
2012 Pendyala G, Ninemire C, Fox HS. Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. Plos One. 7: e38909. PMID 22715419 DOI: 10.1371/Journal.Pone.0038909  0.332
2012 Pendyala G, Buescher JL, Fox HS. Methamphetamine and inflammatory cytokines increase neuronal Na+/K+-ATPase isoform 3: relevance for HIV associated neurocognitive disorders. Plos One. 7: e37604. PMID 22662178 DOI: 10.1371/Journal.Pone.0037604  0.415
2012 Fox HS, Gendelman HE. Commentary: Animal models of neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 301-5. PMID 22549136 DOI: 10.1007/S11481-012-9368-X  0.389
2012 Jagadish T, Pottiez G, Fox HS, Ciborowski P. Plasma gelsolin accumulates in macrophage nodules in brains of simian immunodeficiency virus infected rhesus macaques. Journal of Neurovirology. 18: 113-9. PMID 22403026 DOI: 10.1007/S13365-012-0085-2  0.438
2012 Winkler JM, Chaudhuri AD, Fox HS. Translating the brain transcriptome in neuroAIDS: from non-human primates to humans. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 372-9. PMID 22367717 DOI: 10.1007/S11481-012-9344-5  0.382
2012 Pottiez G, Jagadish T, Yu F, Letendre S, Ellis R, Duarte NA, Grant I, Gendelman HE, Fox HS, Ciborowski P. Plasma proteomic profiling in HIV-1 infected methamphetamine abusers. Plos One. 7: e31031. PMID 22359561 DOI: 10.1371/Journal.Pone.0031031  0.389
2012 Wiederin JL, Yu F, Donahoe RM, Fox HS, Ciborowski P, Gendelman HE. Changes in the plasma proteome follows chronic opiate administration in simian immunodeficiency virus infected rhesus macaques. Drug and Alcohol Dependence. 120: 105-12. PMID 21821369 DOI: 10.1016/J.Drugalcdep.2011.07.009  0.365
2011 Yelamanchili SV, Chaudhuri AD, Flynn CT, Fox HS. Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism. Molecular Neurodegeneration. 6: 52. PMID 21777416 DOI: 10.1186/1750-1326-6-52  0.301
2011 Kraft-Terry SD, Engebretsen IL, Bastola DK, Fox HS, Ciborowski P, Gendelman HE. Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage. Journal of Proteome Research. 10: 2852-62. PMID 21500866 DOI: 10.1021/Pr200124J  0.427
2011 Pendyala G, Trauger SA, Siuzdak G, Fox HS. Short communication: quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity. Aids Research and Human Retroviruses. 27: 179-82. PMID 20929344 DOI: 10.1089/Aid.2010.0090  0.349
2010 Yelamanchili SV, Chaudhuri AD, Chen LN, Xiong H, Fox HS. MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease. Cell Death & Disease. 1: e77. PMID 21170291 DOI: 10.1038/Cddis.2010.56  0.347
2010 Wiederin JL, Donahoe RM, Anderson JR, Yu F, Fox HS, Gendelman HE, Ciborowski PS. Plasma proteomic analysis of simian immunodeficiency virus infection of rhesus macaques. Journal of Proteome Research. 9: 4721-31. PMID 20677826 DOI: 10.1021/Pr1004345  0.369
2010 Marcondes MC, Flynn C, Watry DD, Zandonatti M, Fox HS. Methamphetamine increases brain viral load and activates natural killer cells in simian immunodeficiency virus-infected monkeys. The American Journal of Pathology. 177: 355-61. PMID 20489154 DOI: 10.2353/Ajpath.2010.090953  0.465
2010 Pendyala G, Fox HS. Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders. Genome Medicine. 2: 22. PMID 20353544 DOI: 10.1186/Gm143  0.351
2010 Fox HS. Advances in the "omics" for diagnosis, pathogenesis, and therapeutic development. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 1-3. PMID 20143174 DOI: 10.1007/S11481-010-9194-Y  0.374
2010 Pendyala G, Trauger SA, Siuzdak G, Fox HS. Quantitative plasma proteomic profiling identifies the vitamin E binding protein afamin as a potential pathogenic factor in SIV induced CNS disease. Journal of Proteome Research. 9: 352-8. PMID 19908921 DOI: 10.1021/Pr900685U  0.376
2009 Kraft-Terry SD, Buch SJ, Fox HS, Gendelman HE. A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection. Neuron. 64: 133-45. PMID 19840555 DOI: 10.1016/J.Neuron.2009.09.042  0.403
2009 Gersten M, Alirezaei M, Marcondes MC, Flynn C, Ravasi T, Ideker T, Fox HS. An integrated systems analysis implicates EGR1 downregulation in simian immunodeficiency virus encephalitis-induced neural dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12467-76. PMID 19812322 DOI: 10.1523/Jneurosci.3180-09.2009  0.442
2009 Marcondes MC, Flynn C, Huitron-Rezendiz S, Watry DD, Zandonatti M, Fox HS. Early antiretroviral treatment prevents the development of central nervous system abnormalities in simian immunodeficiency virus-infected rhesus monkeys. Aids (London, England). 23: 1187-95. PMID 19455015 DOI: 10.1097/Qad.0B013E32832C4Af0  0.425
2009 Pendyala G, Trauger SA, Kalisiak E, Ellis RJ, Siuzdak G, Fox HS. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys. Journal of Proteome Research. 8: 2253-60. PMID 19281240 DOI: 10.1021/Pr800854T  0.395
2009 Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb AL, Frausto RF, Bhan V, Kiosses WB, Whitton JL, Robertson GS, Crocker SJ. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy. 5: 152-8. PMID 19066443 DOI: 10.4161/Auto.5.2.7348  0.304
2008 Crews L, Lentz MR, Gonzalez RG, Fox HS, Masliah E. Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS. Journal of Neurovirology. 14: 327-39. PMID 18780234 DOI: 10.1080/13550280802132840  0.416
2008 Fox HS. Virus-host interaction in the simian immunodeficiency virus-infected brain. Journal of Neurovirology. 14: 286-91. PMID 18780229 DOI: 10.1080/13550280802132824  0.421
2008 Alirezaei M, Kiosses WB, Fox HS. Decreased neuronal autophagy in HIV dementia: a mechanism of indirect neurotoxicity. Autophagy. 4: 963-6. PMID 18772620 DOI: 10.4161/Auto.6805  0.401
2008 Alirezaei M, Kiosses WB, Flynn CT, Brady NR, Fox HS. Disruption of neuronal autophagy by infected microglia results in neurodegeneration. Plos One. 3: e2906. PMID 18682838 DOI: 10.1371/Journal.Pone.0002906  0.366
2008 Marcondes MC, Watry D, Zandonatti M, Flynn C, Taffe MA, Fox H. Chronic alcohol consumption generates a vulnerable immune environment during early SIV infection in rhesus macaques. Alcoholism, Clinical and Experimental Research. 32: 1583-92. PMID 18616669 DOI: 10.1111/J.1530-0277.2008.00730.X  0.381
2008 Burdo TH, Ellis RJ, Fox HS. Osteopontin is increased in HIV-associated dementia. The Journal of Infectious Diseases. 198: 715-22. PMID 18616394 DOI: 10.1086/590504  0.429
2008 Marcondes MC, Sopper S, Sauermann U, Burdo TH, Watry D, Zandonatti M, Fox HS. CD4 deficits and disease course acceleration can be driven by a collapse of the CD8 response in rhesus macaques infected with simian immunodeficiency virus. Aids (London, England). 22: 1441-52. PMID 18614867 DOI: 10.1097/Qad.0B013E3283052Fb5  0.329
2008 Wikoff WR, Pendyala G, Siuzdak G, Fox HS. Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. The Journal of Clinical Investigation. 118: 2661-9. PMID 18521184 DOI: 10.1172/Jci34138  0.405
2008 Marcondes MC, Lanigan CM, Burdo TH, Watry DD, Fox HS. Increased expression of monocyte CD44v6 correlates with the deveopment of encephalitis in rhesus macaques infected with simian immunodeficiency virus. The Journal of Infectious Diseases. 197: 1567-76. PMID 18471064 DOI: 10.1086/588002  0.416
2008 Gaskill PJ, Zandonatti M, Gilmartin T, Head SR, Fox HS. Macrophage-derived simian immunodeficiency virus exhibits enhanced infectivity by comparison with T-cell-derived virus. Journal of Virology. 82: 1615-21. PMID 18045942 DOI: 10.1128/Jvi.01757-07  0.73
2007 Persidsky Y, Fox H. Battle of animal models. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 171-7. PMID 18040841 DOI: 10.1007/S11481-006-9046-Y  0.347
2007 Pendyala G, Want EJ, Webb W, Siuzdak G, Fox HS. Biomarkers for neuroAIDS: the widening scope of metabolomics. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 72-80. PMID 18040828 DOI: 10.1007/S11481-006-9041-3  0.354
2007 Alirezaei M, Watry DD, Flynn CF, Kiosses WB, Masliah E, Williams BR, Kaul M, Lipton SA, Fox HS. Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11047-55. PMID 17928446 DOI: 10.1523/Jneurosci.2733-07.2007  0.369
2007 Huitron-Resendiz S, Marcondes MC, Flynn CT, Lanigan CM, Fox HS. Effects of simian immunodeficiency virus on the circadian rhythms of body temperature and gross locomotor activity. Proceedings of the National Academy of Sciences of the United States of America. 104: 15138-43. PMID 17846423 DOI: 10.1073/Pnas.0707171104  0.372
2007 Marcondes MC, Burdo TH, Sopper S, Huitron-Resendiz S, Lanigan C, Watry D, Flynn C, Zandonatti M, Fox HS. Enrichment and persistence of virus-specific CTL in the brain of simian immunodeficiency virus-infected monkeys is associated with a unique cytokine environment. Journal of Immunology (Baltimore, Md. : 1950). 178: 5812-9. PMID 17442965 DOI: 10.4049/Jimmunol.178.9.5812  0.373
2007 Burdo TH, Wood MR, Fox HS. Osteopontin prevents monocyte recirculation and apoptosis. Journal of Leukocyte Biology. 81: 1504-11. PMID 17369493 DOI: 10.1189/Jlb.1106711  0.377
2007 Marcondes MC, Penedo MC, Lanigan C, Hall D, Watry DD, Zandonatti M, Fox HS. Simian immunodeficiency virus-induced CD4+ T cell deficits in cytokine secretion profile are dependent on monkey origin. Viral Immunology. 19: 679-89. PMID 17201663 DOI: 10.1089/Vim.2006.19.679  0.404
2007 Marcondes MC, Burdo T, Lanigan C, Fox H, Watry D. Peripheral Markers of Encephalitis on Monocytes from SIV-infected Rhesus Monkeys Clinical Immunology. 123: S184. DOI: 10.1016/J.Clim.2007.03.169  0.351
2006 Berman JW, Carson MJ, Chang L, Cox BM, Fox HS, Gonzalez RG, Hanson GR, Hauser KF, Ho WZ, Hong JS, Major EO, Maragos WF, Masliah E, McArthur JC, Miller DB, et al. NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 351-99. PMID 18040811 DOI: 10.1007/S11481-006-9048-9  0.619
2006 Burdo TH, Katner SN, Taffe MA, Fox HS. Neuroimmunity, drugs of abuse, and neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 41-9. PMID 18040790 DOI: 10.1007/S11481-005-9001-3  0.399
2006 Chatterji U, Bobardt MD, Gaskill P, Sheeter D, Fox H, Gallay PA. Trim5α Accelerates Degradation of Cytosolic Capsid Associated with Productive HIV-1 Entry Journal of Biological Chemistry. 281: 37025-37033. PMID 17028189 DOI: 10.1074/Jbc.M606066200  0.694
2006 Roberts ES, Huitron-Resendiz S, Taffe MA, Marcondes MC, Flynn CT, Lanigan CM, Hammond JA, Head SR, Henriksen SJ, Fox HS. Host response and dysfunction in the CNS during chronic simian immunodeficiency virus infection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4577-85. PMID 16641237 DOI: 10.1523/Jneurosci.4504-05.2006  0.453
2005 Everall I, Salaria S, Roberts E, Corbeil J, Sasik R, Fox H, Grant I, Masliah E. Methamphetamine stimulates interferon inducible genes in HIV infected brain Journal of Neuroimmunology. 170: 158-171. PMID 16249037 DOI: 10.1016/J.Jneuroim.2005.09.009  0.397
2005 Burdo TH, Marcondes MC, Lanigan CM, Penedo MC, Fox HS. Susceptibility of Chinese rhesus monkeys to SIV infection. Aids (London, England). 19: 1704-6. PMID 16184046 DOI: 10.1097/01.Aids.0000186823.76230.33  0.392
2005 Marcondes MC, Furtado GC, Wensky A, Curotto de Lafaille MA, Fox HS, Lafaille JJ. Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis. The American Journal of Pathology. 166: 1749-60. PMID 15920160 DOI: 10.1016/S0002-9440(10)62485-6  0.562
2005 Gaskill PJ, Watry DD, Burdo TH, Fox HS. Development and characterization of positively selected brain-adapted SIV. Virology Journal. 2: 44. PMID 15890081 DOI: 10.1186/1743-422X-2-44  0.724
2005 Roberts ES, Masliah E, Fox HS. CD163 identifies a unique population of ramified microglia in HIV encephalitis (HIVE). Journal of Neuropathology and Experimental Neurology. 63: 1255-64. PMID 15624762 DOI: 10.1093/Jnen/63.12.1255  0.365
2004 Masliah E, Roberts ES, Langford D, Everall I, Crews L, Adame A, Rockenstein E, Fox HS. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis Journal of Neuroimmunology. 157: 163-175. PMID 15579294 DOI: 10.1016/J.Jneuroim.2004.08.026  0.381
2004 Roberts ES, Burudi EM, Flynn C, Madden LJ, Roinick KL, Watry DD, Zandonatti MA, Taffe MA, Fox HS. Acute SIV infection of the brain leads to upregulation of IL6 and interferon-regulated genes: expression patterns throughout disease progression and impact on neuroAIDS. Journal of Neuroimmunology. 157: 81-92. PMID 15579284 DOI: 10.1016/J.Jneuroim.2004.08.030  0.373
2004 Huitron-Resendiz S, De Rozières S, Sanchez-Alavez M, Bühler B, Lin YC, Lerner DL, Henriksen NW, Burudi M, Fox HS, Torbett BE, Henriksen S, Elder JH. Resolution and prevention of feline immunodeficiency virus-induced neurological deficits by treatment with the protease inhibitor TL-3. Journal of Virology. 78: 4525-32. PMID 15078933 DOI: 10.1128/Jvi.78.9.4525-4532.2004  0.303
2004 Weed MR, Gold LH, Polis I, Koob GF, Fox HS, Taffe MA. Impaired performance on a rhesus monkey neuropsychological testing battery following simian immunodeficiency virus infection. Aids Research and Human Retroviruses. 20: 77-89. PMID 15000701 DOI: 10.1089/088922204322749521  0.36
2004 Madden LJ, Zandonatti MA, Flynn CT, Taffe MA, Marcondes MC, Schmitz JE, Reimann KA, Henriksen SJ, Fox HS. CD8+ cell depletion amplifies the acute retroviral syndrome. Journal of Neurovirology. 10: 58-66. PMID 14982741 DOI: 10.1080/753312754  0.34
2003 Marcondes MC, Phillipson CA, Fox HS. Distinct clonal repertoire of brain CD8+ cells in simian immunodeficiency virus infection. Aids (London, England). 17: 1605-11. PMID 12853742 DOI: 10.1097/00002030-200307250-00004  0.426
2003 Roberts ES, Zandonatti MA, Watry DD, Madden LJ, Henriksen SJ, Taffe MA, Fox HS. Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. The American Journal of Pathology. 162: 2041-57. PMID 12759259 DOI: 10.1016/S0002-9440(10)64336-2  0.45
2003 Kim SH, Cleary MM, Fox HS, Chantry D, Sarvetnick N. CCR4-bearing T cells participate in autoimmune diabetes. The Journal of Clinical Investigation. 110: 1675-86. PMID 12464673 DOI: 10.1172/Jci15547  0.312
2002 Burudi EM, Marcondes MC, Watry DD, Zandonatti M, Taffe MA, Fox HS. Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains. Journal of Virology. 76: 12233-41. PMID 12414962 DOI: 10.1128/Jvi.76.23.12233-12241.2002  0.406
2002 Fox HS, Phillips TR. FIV and neuroAIDS. Journal of Neurovirology. 8: 155-7. PMID 12053270 DOI: 10.1080/13550280290049714  0.463
2002 Burudi EM, Fox HS. Simian immunodeficiency virus model of HIV-induced central nervous system dysfunction. Advances in Virus Research. 56: 435-68. PMID 11450309 DOI: 10.1016/S0065-3527(01)56035-2  0.439
2001 Marcondes MC, Burudi EM, Huitron-Resendiz S, Sanchez-Alavez M, Watry D, Zandonatti M, Henriksen SJ, Fox HS. Highly activated CD8(+) T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 5429-38. PMID 11673562 DOI: 10.4049/Jimmunol.167.9.5429  0.43
2001 Asensio VC, Maier J, Milner R, Boztug K, Kincaid C, Moulard M, Phillipson C, Lindsley K, Krucker T, Fox HS, Campbell IL. Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro. Journal of Virology. 75: 7067-77. PMID 11435587 DOI: 10.1128/Jvi.75.15.7067-7077.2001  0.477
2000 Fox HS, Weed MR, Huitron-Resendiz S, Baig J, Horn TF, Dailey PJ, Bischofberger N, Henriksen SJ. Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus-infected monkeys. The Journal of Clinical Investigation. 106: 37-45. PMID 10880046 DOI: 10.1172/Jci9102  0.416
2000 Lane TE, Liu MT, Chen BP, Asensio VC, Samawi RM, Paoletti AD, Campbell IL, Kunkel SL, Fox HS, Buchmeier MJ. A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination. Journal of Virology. 74: 1415-24. PMID 10627552 DOI: 10.1128/Jvi.74.3.1415-1424.2000  0.325
1999 Lane TE, Fox HS, Buchmeier MJ. Inhibition of nitric oxide synthase-2 reduces the severity of mouse hepatitis virus-induced demyelination: implications for NOS2/NO regulation of chemokine expression and inflammation. Journal of Neurovirology. 5: 48-54. PMID 10190690 DOI: 10.3109/13550289909029745  0.303
1998 Horn TF, Huitron-Resendiz S, Weed MR, Henriksen SJ, Fox HS. Early physiological abnormalities after simian immunodeficiency virus infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 15072-7. PMID 9844017 DOI: 10.1073/Pnas.95.25.15072  0.409
1998 Gold LH, Fox HS, Henriksen SJ, Buchmeier MJ, Weed MR, Taffe MA, Huitrón-Resendiz S, Horn TF, Bloom FE. Longitudinal analysis of behavioral, neurophysiological, viral and immunological effects of SIV infection in rhesus monkeys. Journal of Medical Primatology. 27: 104-12. PMID 9747951 DOI: 10.1111/J.1600-0684.1998.Tb00234.X  0.404
1998 Strelow LI, Watry DD, Fox HS, Nelson JA. Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIVmac variant. Journal of Neurovirology. 4: 269-80. PMID 9639070 DOI: 10.3109/13550289809114528  0.368
1998 Lee T, Laco GS, Torbett BE, Fox HS, Lerner DL, Elder JH, Wong CH. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 939-44. PMID 9448264 DOI: 10.1073/Pnas.95.3.939  0.346
1998 Fox H, Horn T, Miller-Wing A, Weed M, Gold L, Huitron-Resendiz S, Henriksen S. Immune and functional consequences of neurovirulent SIV infection Journal of Neuroimmunology. 90: 65. DOI: 10.1016/S0165-5728(98)91569-7  0.321
1997 Fox HS, Gold LH, Henriksen SJ, Bloom FE. Simian immunodeficiency virus: a model for neuroAIDS. Neurobiology of Disease. 4: 265-74. PMID 9361303 DOI: 10.1006/Nbdi.1997.0159  0.434
1997 Jacobson S, Henriksen SJ, Prospero-Garcia O, Phillips TR, Elder JH, Young WG, Bloom FE, Fox HS. Cortical neuronal cytoskeletal changes associated with FIV infection. Journal of Neurovirology. 3: 283-9. PMID 9291236 DOI: 10.3109/13550289709029469  0.411
1996 Phillips TR, Prospero-Garcia O, Wheeler DW, Wagaman PC, Lerner DL, Fox HS, Whalen LR, Bloom FE, Elder JH, Henriksen SJ. Neurologic dysfunctions caused by a molecular clone of feline immunodeficiency virus, FIV-PPR. Journal of Neurovirology. 2: 388-96. PMID 8972420 DOI: 10.3109/13550289609146904  0.399
1996 Prospéro-García O, Gold LH, Fox HS, Polis I, Koob GF, Bloom FE, Henriksen SJ. Microglia-passaged simian immunodeficiency virus induces neurophysiological abnormalities in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 93: 14158-63. PMID 8943077 DOI: 10.1073/Pnas.93.24.14158  0.374
1996 Lane TE, Buchmeier MJ, Watry DD, Fox HS. Expression of Inflammatory Cytokines and Inducible Nitric Oxide Synthase in Brains of SIV-Infected Rhesus Monkeys: Applications to HIV-Induced Central Nervous System Disease Molecular Medicine. 2: 27-37. DOI: 10.1007/Bf03402200  0.436
1995 Lerner DL, Wagaman PC, Phillips TR, Prospero-Garcia O, Henriksen SJ, Fox HS, Bloom FE, Elder JH. Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase. Proceedings of the National Academy of Sciences of the United States of America. 92: 7480-4. PMID 7638216 DOI: 10.1073/Pnas.92.16.7480  0.359
1995 Henriksen SJ, Prospero-Garcia O, Phillips TR, Fox HS, Bloom FE, Elder JH. Feline immunodeficiency virus as a model for study of lentivirus infection of the central nervous system. Current Topics in Microbiology and Immunology. 202: 167-86. PMID 7587362 DOI: 10.1007/978-3-642-79657-9_12  0.446
1995 Lane TE, Buchmeier MJ, Watry DD, Jakubowski DB, Fox HS. Serial passage of microglial SIV results in selection of homogeneous env quasispecies in the brain. Virology. 212: 458-65. PMID 7571415 DOI: 10.1006/Viro.1995.1503  0.455
1994 Phillips TR, Prospero-Garcia O, Puaoi DL, Lerner DL, Fox HS, Olmsted RA, Bloom FE, Henriksen SJ, Elder JH. Neurological abnormalities associated with feline immunodeficiency virus infection. The Journal of General Virology. 75: 979-87. PMID 8176384 DOI: 10.1099/0022-1317-75-5-979  0.422
1987 Martin GR, Silver LM, Fox HS, Joyner AL. Establishment of embryonic stem cell lines from preimplantation mouse embryos homozygous for lethal mutations in the t-complex. Developmental Biology. 121: 20-8. PMID 2883053 DOI: 10.1016/0012-1606(87)90134-5  0.642
1985 Fox HS, Martin GR, Lyon MF, Herrmann B, Frischauf AM, Lehrach H, Silver LM. Molecular probes define different regions of the mouse t complex. Cell. 40: 63-9. PMID 2981632 DOI: 10.1016/0092-8674(85)90309-5  0.537
1984 Fox HS, Silver LM, Martin GR. An alpha globin pseudogene is located within the mouse t complex. Immunogenetics. 19: 125-30. PMID 6321339 DOI: 10.1007/BF00387855  0.486
1984 Fox HS, Silver LM, Martin GR. An alpha globin pseudogene is located within the mouse t complex Immunogenetics. 19: 368-368. DOI: 10.1007/BF00345413  0.477
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