| Year |
Citation |
Score |
| 2023 |
Oh CK, Piña-Crespo J, Talantova M, Carnevale LN, Stoneham C, Lewinski M, Guatelli J, Lipton SA. Reply to: Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nature Chemical Biology. 19: 1306-1308. PMID 37798355 DOI: 10.1038/s41589-023-01425-z |
0.655 |
|
| 2022 |
Oh CK, Nakamura T, Beutler N, Zhang X, Piña-Crespo J, Talantova M, Ghatak S, Trudler D, Carnevale LN, McKercher SR, Bakowski MA, Diedrich JK, Roberts AJ, Woods AK, Chi V, ... ... Lipton SA, et al. Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nature Chemical Biology. PMID 36175661 DOI: 10.1038/s41589-022-01149-6 |
0.674 |
|
| 2022 |
Oh CK, Nakamura T, Beutler N, Zhang X, Piña-Crespo J, Talantova M, Ghatak S, Trudler D, Carnevale LN, McKercher SR, Bakowski MA, Diedrich JK, Roberts AJ, Woods AK, Chi V, ... ... Lipton SA, et al. Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 35411336 DOI: 10.1101/2022.04.05.487060 |
0.673 |
|
| 2021 |
Trudler D, Sanz-Blasco S, Eisele YS, Ghatak S, Bodhinathan K, Akhtar MW, Lynch WP, Piña-Crespo JC, Talantova M, Kelly JW, Lipton SA. α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33483428 DOI: 10.1523/JNEUROSCI.1871-20.2020 |
0.801 |
|
| 2020 |
Ghatak S, Dolatabadi N, Gao R, Wu Y, Scott H, Trudler D, Sultan A, Ambasudhan R, Nakamura T, Masliah E, Talantova M, Voytek B, Lipton SA. NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. Molecular Psychiatry. PMID 32467645 DOI: 10.1038/S41380-020-0776-7 |
0.324 |
|
| 2019 |
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA. Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control. Elife. 8. PMID 31782729 DOI: 10.7554/Elife.50333 |
0.36 |
|
| 2019 |
Nakamura T, Lipton SA. Nitric Oxide-Dependent Protein Posttranslational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases. Antioxidants & Redox Signaling. PMID 31657228 DOI: 10.1089/ars.2019.7916 |
0.309 |
|
| 2019 |
Okamoto SI, Prikhodko O, Pina-Crespo J, Adame A, McKercher SR, Brill LM, Nakanishi N, Oh CK, Nakamura T, Masliah E, Lipton SA. NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model. Neurobiology of Disease. PMID 30928642 DOI: 10.1016/J.Nbd.2019.03.029 |
0.716 |
|
| 2019 |
Trudler D, Lipton SA. Novel Direct Conversion of Microglia to Neurons. Trends in Molecular Medicine. PMID 30611669 DOI: 10.1016/j.molmed.2018.12.005 |
0.35 |
|
| 2019 |
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA. Author response: Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls Elife. DOI: 10.7554/Elife.50333.Sa2 |
0.332 |
|
| 2018 |
Ryan T, Bamm VV, Stykel MG, Coackley CL, Humphries KM, Jamieson-Williams R, Ambasudhan R, Mosser DD, Lipton SA, Harauz G, Ryan SD. Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein. Nature Communications. 9: 817. PMID 29483518 DOI: 10.1038/S41467-018-03241-9 |
0.588 |
|
| 2017 |
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, ... ... Lipton SA, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4 |
0.534 |
|
| 2017 |
Oh CK, Sultan A, Platzer J, Dolatabadi N, Soldner F, McClatchy DB, Diedrich JK, Yates JR, Ambasudhan R, Nakamura T, Jaenisch R, Lipton SA. S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models. Cell Reports. 21: 2171-2182. PMID 29166608 DOI: 10.1016/J.Celrep.2017.10.068 |
0.336 |
|
| 2017 |
Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, ... ... Lipton SA, et al. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nature Communications. 8: 1488. PMID 29133852 DOI: 10.1038/S41467-017-01563-8 |
0.722 |
|
| 2017 |
Nakamura T, Lipton SA. 'SNO'-Storms Compromise Protein Activity and Mitochondrial Metabolism in Neurodegenerative Disorders. Trends in Endocrinology and Metabolism: Tem. PMID 29097102 DOI: 10.1016/j.tem.2017.10.004 |
0.311 |
|
| 2017 |
Nagar S, Trudler D, McKercher SR, Piña-Crespo J, Nakanishi N, Okamoto SI, Lipton SA. Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency. Investigative Ophthalmology & Visual Science. 58: 3741-3749. PMID 28738418 DOI: 10.1167/iovs.17-21767 |
0.691 |
|
| 2017 |
Nagar S, Noveral SM, Trudler D, Lopez KM, McKercher SR, Han X, Yates JR, Piña-Crespo JC, Nakanishi N, Satoh T, Okamoto SI, Lipton SA. MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 28461502 DOI: 10.1073/Pnas.1613067114 |
0.701 |
|
| 2016 |
Lipton SA, Rezaie T, Nutter A, Lopez KM, Parker J, Kosaka K, Satoh T, McKercher SR, Masliah E, Nakanishi N. Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models. Cell Death & Disease. 7: e2499. PMID 27906174 DOI: 10.1038/Cddis.2016.389 |
0.331 |
|
| 2016 |
Sunico CR, Sultan A, Nakamura T, Dolatabadi N, Parker J, Shan B, Han X, Yates JR, Masliah E, Ambasudhan R, Nakanishi N, Lipton SA. Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821734 DOI: 10.1073/Pnas.1608784113 |
0.376 |
|
| 2016 |
Macrez R, Stys PK, Vivien D, Lipton SA, Docagne F. Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities. The Lancet. Neurology. 15: 1089-1102. PMID 27571160 DOI: 10.1016/S1474-4422(16)30165-X |
0.366 |
|
| 2016 |
Sanz-Blasco S, Piña-Crespo JC, Zhang X, McKercher SR, Lipton SA. Levetiracetam inhibits oligomeric Aβ-induced glutamate release from human astrocytes. Neuroreport. PMID 27183239 DOI: 10.1097/Wnr.0000000000000601 |
0.718 |
|
| 2016 |
Jiang J, Chan A, Ali S, Saha A, Haushalter KJ, Lam WM, Glasheen M, Parker J, Brenner M, Mahon SB, Patel HH, Ambasudhan R, Lipton SA, Pilz RB, Boss GR. Hydrogen Sulfide-Mechanisms of Toxicity and Development of an Antidote. Scientific Reports. 6: 20831. PMID 26877209 DOI: 10.1038/Srep20831 |
0.315 |
|
| 2016 |
Takahashi H, Xia P, Cui J, Talantova M, Bodhinathan K, Li W, Saleem S, Holland EA, Tong G, Piña-Crespo J, Zhang D, Nakanishi N, Larrick JW, McKercher SR, Nakamura T, ... ... Lipton SA, et al. Corrigendum: Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease. Scientific Reports. 6: 20750. PMID 26867695 DOI: 10.1038/srep20750 |
0.76 |
|
| 2016 |
Akhtar MW, Sanz-Blasco S, Dolatabadi N, Parker J, Chon K, Lee MS, Soussou W, McKercher SR, Ambasudhan R, Nakamura T, Lipton SA. Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation. Nature Communications. 7: 10242. PMID 26743041 DOI: 10.1038/Ncomms10242 |
0.749 |
|
| 2016 |
Nakamura T, Lipton SA. Protein S-Nitrosylation as a Therapeutic Target for Neurodegenerative Diseases. Trends in Pharmacological Sciences. 37: 73-84. PMID 26707925 DOI: 10.1016/j.tips.2015.10.002 |
0.341 |
|
| 2015 |
Chen S, Cui J, Jiang T, Olson ES, Cai QY, Yang M, Wu W, Guthrie JM, Robertson JD, Lipton SA, Ma L, Tsien RY, Gu Z. Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26681768 DOI: 10.1177/0271678X15621573 |
0.314 |
|
| 2015 |
Takahashi H, Xia P, Cui J, Talantova M, Bodhinathan K, Li W, Holland EA, Tong G, Piña-Crespo J, Zhang D, Nakanishi N, Larrick JW, McKercher SR, Nakamura T, Wang Y, ... Lipton SA, et al. Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease. Scientific Reports. 5: 14781. PMID 26477507 DOI: 10.1038/srep14781 |
0.794 |
|
| 2015 |
Nakato R, Ohkubo Y, Konishi A, Shibata M, Kaneko Y, Iwawaki T, Nakamura T, Lipton SA, Uehara T. Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress. Scientific Reports. 5: 14812. PMID 26446798 DOI: 10.1038/srep14812 |
0.341 |
|
| 2015 |
Nakanishi N, Kang YJ, Tu S, McKercher SR, Masliah E, Lipton SA. Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model. Journal of Molecular Neuroscience : Mn. PMID 26374431 DOI: 10.1007/S12031-015-0651-1 |
0.404 |
|
| 2015 |
Satoh T, Stalder R, McKercher SR, Williamson RE, Roth GP, Lipton SA. Nrf2 and HSF-1 Pathway Activation via Hydroquinone-Based Proelectrophilic Small Molecules is Regulated by Electrochemical Oxidation Potential. Asn Neuro. 7. PMID 26243592 DOI: 10.1177/1759091415593294 |
0.312 |
|
| 2015 |
Nakamura T, Lipton SA. Nitrosative Stress in the Nervous System: Guidelines for Designing Experimental Strategies to Study Protein S-Nitrosylation. Neurochemical Research. PMID 26118537 DOI: 10.1007/s11064-015-1640-z |
0.306 |
|
| 2015 |
Yang B, Qu M, Wang R, Chatterton JE, Liu XB, Zhu B, Narisawa S, Millan JL, Nakanishi N, Swoboda K, Lipton SA, Zhang D. The critical role of membralin in postnatal motor neuron survival and disease. Elife. 4. PMID 25977983 DOI: 10.7554/eLife.06500 |
0.34 |
|
| 2015 |
Nakamura T, Prikhodko OA, Pirie E, Nagar S, Akhtar MW, Oh CK, McKercher SR, Ambasudhan R, Okamoto SI, Lipton SA. Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiology of Disease. PMID 25796565 DOI: 10.1016/j.nbd.2015.03.017 |
0.377 |
|
| 2015 |
Zhang D, Lee B, Nutter A, Song P, Dolatabadi N, Parker J, Sanz-Blasco S, Newmeyer T, Ambasudhan R, McKercher SR, Masliah E, Lipton SA. Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid. Journal of Neurochemistry. 133: 898-908. PMID 25692407 DOI: 10.1111/Jnc.13074 |
0.373 |
|
| 2015 |
Okamoto SI, Lipton SA. S-Nitrosylation in neurogenesis and neuronal development. Biochimica Et Biophysica Acta. 1850: 1588-1593. PMID 25527866 DOI: 10.1016/j.bbagen.2014.12.013 |
0.316 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Lipton SA, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.307 |
|
| 2014 |
Tu S, Okamoto S, Lipton SA, Xu H. Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease. Molecular Neurodegeneration. 9: 48. PMID 25394486 DOI: 10.1186/1750-1326-9-48 |
0.383 |
|
| 2014 |
Choi MS, Nakamura T, Cho SJ, Han X, Holland EA, Qu J, Petsko GA, Yates JR, Liddington RC, Lipton SA. Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15123-31. PMID 25378175 DOI: 10.1523/Jneurosci.4751-13.2014 |
0.362 |
|
| 2014 |
Okamoto S, Nakamura T, Cieplak P, Chan SF, Kalashnikova E, Liao L, Saleem S, Han X, Clemente A, Nutter A, Sances S, Brechtel C, Haus D, Haun F, Sanz-Blasco S, ... ... Lipton SA, et al. S-nitrosylation-mediated redox transcriptional switch modulates neurogenesis and neuronal cell death. Cell Reports. 8: 217-28. PMID 25001280 DOI: 10.1016/J.Celrep.2014.06.005 |
0.597 |
|
| 2014 |
Ambasudhan R, Dolatabadi N, Nutter A, Masliah E, Mckercher SR, Lipton SA. Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells. The Journal of Comparative Neurology. 522: 2845-56. PMID 24756727 DOI: 10.1002/Cne.23617 |
0.312 |
|
| 2014 |
Molokanova E, Akhtar MW, Sanz-Blasco S, Tu S, Piña-Crespo JC, McKercher SR, Lipton SA. Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5023-8. PMID 24695719 DOI: 10.1523/Jneurosci.2907-13.2014 |
0.746 |
|
| 2014 |
Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, ... ... Lipton SA, et al. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research. 24: 126-9. PMID 24296783 DOI: 10.1038/Cr.2013.156 |
0.537 |
|
| 2014 |
Jeon GS, Nakamura T, Lee JS, Choi WJ, Ahn SW, Lee KW, Sung JJ, Lipton SA. Potential effect of S-nitrosylated protein disulfide isomerase on mutant SOD1 aggregation and neuronal cell death in amyotrophic lateral sclerosis. Molecular Neurobiology. 49: 796-807. PMID 24091828 DOI: 10.1007/s12035-013-8562-z |
0.376 |
|
| 2013 |
Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, ... ... Lipton SA, et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. Cell. 155: 1351-64. PMID 24290359 DOI: 10.1016/J.Cell.2013.11.009 |
0.587 |
|
| 2013 |
Nakanishi N, Ryan SD, Zhang X, Khan A, Holland T, Cho EG, Huang X, Liao FF, Xu H, Lipton SA, Tu S. Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14170-83. PMID 23986251 DOI: 10.1523/Jneurosci.4646-10.2013 |
0.585 |
|
| 2013 |
Sunico CR, Nakamura T, Rockenstein E, Mante M, Adame A, Chan SF, Newmeyer TF, Masliah E, Nakanishi N, Lipton SA. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Molecular Neurodegeneration. 8: 29. PMID 23985028 DOI: 10.1186/1750-1326-8-29 |
0.312 |
|
| 2013 |
Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8. PMID 23852340 DOI: 10.1038/Nm.3246 |
0.408 |
|
| 2013 |
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Lipton SA, et al. Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E2518-27. PMID 23776240 DOI: 10.1073/Pnas.1306832110 |
0.735 |
|
| 2013 |
Nakamura T, Tu S, Akhtar MW, Sunico CR, Okamoto S, Lipton SA. Aberrant protein s-nitrosylation in neurodegenerative diseases. Neuron. 78: 596-614. PMID 23719160 DOI: 10.1016/j.neuron.2013.05.005 |
0.322 |
|
| 2013 |
Haun F, Nakamura T, Shiu AD, Cho DH, Tsunemi T, Holland EA, La Spada AR, Lipton SA. S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease. Antioxidants & Redox Signaling. 19: 1173-84. PMID 23641925 DOI: 10.1089/ars.2012.4928 |
0.351 |
|
| 2013 |
Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, ... ... Lipton SA, et al. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nature Medicine. 19: 473-80. PMID 23524343 DOI: 10.1038/Nm.3117 |
0.361 |
|
| 2013 |
Shi ZQ, Sunico CR, McKercher SR, Cui J, Feng GS, Nakamura T, Lipton SA. S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America. 110: 3137-42. PMID 23382182 DOI: 10.1073/Pnas.1215501110 |
0.415 |
|
| 2013 |
Ambasudhan R, Parker J, Ainza C, Dolatabadi N, Ryan S, Le T, Lipton SA, Haas RH. A human reprogrammed-cell model of MELAS Mitochondrion. 13: 943-944. DOI: 10.1016/j.mito.2013.07.112 |
0.544 |
|
| 2012 |
Piña-Crespo JC, Talantova M, Cho EG, Soussou W, Dolatabadi N, Ryan SD, Ambasudhan R, McKercher S, Deisseroth K, Lipton SA. High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15837-42. PMID 23136422 DOI: 10.1523/Jneurosci.3735-12.2012 |
0.77 |
|
| 2012 |
Rezaie T, McKercher SR, Kosaka K, Seki M, Wheeler L, Viswanath V, Chun T, Joshi R, Valencia M, Sasaki S, Tozawa T, Satoh T, Lipton SA. Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration. Investigative Ophthalmology & Visual Science. 53: 7847-54. PMID 23081978 DOI: 10.1167/iovs.12-10793 |
0.301 |
|
| 2012 |
Akhtar MW, Sunico CR, Nakamura T, Lipton SA. Redox Regulation of Protein Function via Cysteine S-Nitrosylation and Its Relevance to Neurodegenerative Diseases. International Journal of Cell Biology. 2012: 463756. PMID 22956959 DOI: 10.1155/2012/463756 |
0.356 |
|
| 2012 |
Qu J, Nakamura T, Holland EA, McKercher SR, Lipton SA. S-nitrosylation of Cdk5: potential implications in amyloid-β-related neurotoxicity in Alzheimer disease. Prion. 6: 364-70. PMID 22874667 DOI: 10.4161/pri.21250 |
0.377 |
|
| 2012 |
Henson MA, Larsen RS, Lawson SN, Pérez-Otaño I, Nakanishi N, Lipton SA, Philpot BD. Genetic deletion of NR3A accelerates glutamatergic synapse maturation. Plos One. 7: e42327. PMID 22870318 DOI: 10.1371/Journal.Pone.0042327 |
0.369 |
|
| 2012 |
Nakamura T, Cho DH, Lipton SA. Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases. Experimental Neurology. 238: 12-21. PMID 22771760 DOI: 10.1016/j.expneurol.2012.06.032 |
0.388 |
|
| 2012 |
You H, Tsutsui S, Hameed S, Kannanayakal TJ, Chen L, Xia P, Engbers JD, Lipton SA, Stys PK, Zamponi GW. Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 1737-42. PMID 22307640 DOI: 10.1073/Pnas.1110789109 |
0.417 |
|
| 2011 |
Cho EG, Zaremba JD, McKercher SR, Talantova M, Tu S, Masliah E, Chan SF, Nakanishi N, Terskikh A, Lipton SA. MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model. Plos One. 6: e24027. PMID 21901155 DOI: 10.1371/Journal.Pone.0024027 |
0.6 |
|
| 2011 |
Satoh T, Rezaie T, Seki M, Sunico CR, Tabuchi T, Kitagawa T, Yanagitai M, Senzaki M, Kosegawa C, Taira H, McKercher SR, Hoffman JK, Roth GP, Lipton SA. Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes. Journal of Neurochemistry. 119: 569-78. PMID 21883218 DOI: 10.1111/j.1471-4159.2011.07449.x |
0.314 |
|
| 2011 |
Qu J, Nakamura T, Cao G, Holland EA, McKercher SR, Lipton SA. S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide. Proceedings of the National Academy of Sciences of the United States of America. 108: 14330-5. PMID 21844361 DOI: 10.1073/pnas.1105172108 |
0.322 |
|
| 2011 |
Nakamura T, Lipton SA. Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases. Cell Death and Differentiation. 18: 1478-86. PMID 21597461 DOI: 10.1038/cdd.2011.65 |
0.433 |
|
| 2011 |
Meng F, Yao D, Shi Y, Kabakoff J, Wu W, Reicher J, Ma Y, Moosmann B, Masliah E, Lipton SA, Gu Z. Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation. Molecular Neurodegeneration. 6: 34. PMID 21595948 DOI: 10.1186/1750-1326-6-34 |
0.326 |
|
| 2011 |
Kim J, Efe JA, Zhu S, Talantova M, Yuan X, Wang S, Lipton SA, Zhang K, Ding S. Direct reprogramming of mouse fibroblasts to neural progenitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 7838-43. PMID 21521790 DOI: 10.1073/Pnas.1103113108 |
0.318 |
|
| 2011 |
Larsen RS, Corlew RJ, Henson MA, Roberts AC, Mishina M, Watanabe M, Lipton SA, Nakanishi N, Pérez-Otaño I, Weinberg RJ, Philpot BD. NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticity. Nature Neuroscience. 14: 338-44. PMID 21297630 DOI: 10.1038/Nn.2750 |
0.344 |
|
| 2011 |
Krajewska M, Xu L, Xu W, Krajewski S, Kress CL, Cui J, Yang L, Irie F, Yamaguchi Y, Lipton SA, Reed JC. Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Research. 1370: 227-37. PMID 21075086 DOI: 10.1016/j.brainres.2010.11.015 |
0.312 |
|
| 2011 |
Hardingham GE, Lipton SA. Regulation of neuronal oxidative and nitrosative stress by endogenous protective pathways and disease processes. Antioxidants & Redox Signaling. 14: 1421-4. PMID 20977364 DOI: 10.1089/Ars.2010.3573 |
0.369 |
|
| 2011 |
Nakamura T, Lipton SA. S-nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases. Antioxidants & Redox Signaling. 14: 1479-92. PMID 20812868 DOI: 10.1089/ars.2010.3570 |
0.35 |
|
| 2010 |
Kwak YD, Ma T, Diao S, Zhang X, Chen Y, Hsu J, Lipton SA, Masliah E, Xu H, Liao FF. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. Molecular Neurodegeneration. 5: 49. PMID 21067594 DOI: 10.1186/1750-1326-5-49 |
0.346 |
|
| 2010 |
Piña-Crespo JC, Talantova M, Micu I, States B, Chen HS, Tu S, Nakanishi N, Tong G, Zhang D, Heinemann SF, Zamponi GW, Stys PK, Lipton SA. Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11501-5. PMID 20739572 DOI: 10.1523/Jneurosci.1593-10.2010 |
0.722 |
|
| 2010 |
Xia P, Chen HS, Zhang D, Lipton SA. Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11246-50. PMID 20720132 DOI: 10.1523/JNEUROSCI.2488-10.2010 |
0.427 |
|
| 2010 |
Xia K, Xiong H, Shin Y, Wang D, Deerinck T, Takahashi H, Ellisman MH, Lipton SA, Tong G, Descalzi G, Zhang D, Zhuo M, Zhang Z. Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety. Molecular Brain. 3: 23. PMID 20678225 DOI: 10.1186/1756-6606-3-23 |
0.355 |
|
| 2010 |
Nakamura T, Wang L, Wong CC, Scott FL, Eckelman BP, Han X, Tzitzilonis C, Meng F, Gu Z, Holland EA, Clemente AT, Okamoto S, Salvesen GS, Riek R, Yates JR, ... Lipton SA, et al. Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death. Molecular Cell. 39: 184-95. PMID 20670888 DOI: 10.1016/J.Molcel.2010.07.002 |
0.364 |
|
| 2010 |
Cho DH, Nakamura T, Lipton SA. Mitochondrial dynamics in cell death and neurodegeneration. Cellular and Molecular Life Sciences : Cmls. 67: 3435-47. PMID 20577776 DOI: 10.1007/s00018-010-0435-2 |
0.312 |
|
| 2010 |
Nakamura T, Cieplak P, Cho DH, Godzik A, Lipton SA. S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration. Mitochondrion. 10: 573-8. PMID 20447471 DOI: 10.1016/j.mito.2010.04.007 |
0.332 |
|
| 2010 |
Gu Z, Nakamura T, Lipton SA. Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases. Molecular Neurobiology. 41: 55-72. PMID 20333559 DOI: 10.1007/S12035-010-8113-9 |
0.391 |
|
| 2010 |
Nakamura T, Lipton SA. Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer's and Parkinson's diseases. Apoptosis : An International Journal On Programmed Cell Death. 15: 1354-63. PMID 20177970 DOI: 10.1007/s10495-010-0476-x |
0.354 |
|
| 2010 |
Nakamura T, Lipton SA. Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological strategies. Cell Calcium. 47: 190-7. PMID 20060165 DOI: 10.1016/j.ceca.2009.12.009 |
0.385 |
|
| 2010 |
Zhao LC, Yang B, Wang R, Lipton SA, Zhang D. Type C botulinum toxin causes degeneration of motoneurons in vivo. Neuroreport. 21: 14-8. PMID 19907349 DOI: 10.1097/WNR.0b013e328330dcca |
0.334 |
|
| 2010 |
Seki M, Soussou W, Manabe S, Lipton SA. Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity. Investigative Ophthalmology & Visual Science. 51: 1198-207. PMID 19815732 DOI: 10.1167/Iovs.09-4102 |
0.733 |
|
| 2010 |
Sanz-Blasco S, Piña-Crespo J, Talantova M, Lipton S. P2-288: Abeta-mediated glutamate release from astrocytes Alzheimer's & Dementia. 6: S398-S398. DOI: 10.1016/J.Jalz.2010.05.1338 |
0.689 |
|
| 2009 |
Okamoto S, Pouladi MA, Talantova M, Yao D, Xia P, Ehrnhoefer DE, Zaidi R, Clemente A, Kaul M, Graham RK, Zhang D, Vincent Chen HS, Tong G, Hayden MR, Lipton SA. Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. Nature Medicine. 15: 1407-13. PMID 19915593 DOI: 10.1038/Nm.2056 |
0.44 |
|
| 2009 |
Nakamura T, Lipton SA. According to GOSPEL: filling in the GAP(DH) of NO-mediated neurotoxicity. Neuron. 63: 3-6. PMID 19607786 DOI: 10.1016/j.neuron.2009.06.013 |
0.324 |
|
| 2009 |
Nakanishi N, Tu S, Shin Y, Cui J, Kurokawa T, Zhang D, Chen HS, Tong G, Lipton SA. Neuroprotection by the NR3A subunit of the NMDA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5260-5. PMID 19386922 DOI: 10.1523/JNEUROSCI.1067-09.2009 |
0.407 |
|
| 2009 |
Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science (New York, N.Y.). 324: 102-5. PMID 19342591 DOI: 10.1126/Science.1171091 |
0.368 |
|
| 2009 |
Bajpai R, Coppola G, Kaul M, Talantova M, Cimadamore F, Nilbratt M, Geschwind DH, Lipton SA, Terskikh AV. Molecular stages of rapid and uniform neuralization of human embryonic stem cells. Cell Death and Differentiation. 16: 807-25. PMID 19282867 DOI: 10.1038/Cdd.2009.18 |
0.3 |
|
| 2009 |
Lipton SA, Li H, Zaremba JD, McKercher SR, Cui J, Kang YJ, Nie Z, Soussou W, Talantova M, Okamoto S, Nakanishi N. Autistic phenotype from MEF2C knockout cells. Science (New York, N.Y.). 323: 208. PMID 19131610 DOI: 10.1126/Science.323.5911.208B |
0.747 |
|
| 2009 |
Nakamura T, Lipton SA. Cell death: protein misfolding and neurodegenerative diseases. Apoptosis : An International Journal On Programmed Cell Death. 14: 455-68. PMID 19130231 DOI: 10.1007/s10495-008-0301-y |
0.348 |
|
| 2008 |
Seki M, Lipton SA. Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma. Progress in Brain Research. 173: 495-510. PMID 18929130 DOI: 10.1016/S0079-6123(08)01134-5 |
0.415 |
|
| 2008 |
Li H, Radford JC, Ragusa MJ, Shea KL, McKercher SR, Zaremba JD, Soussou W, Nie Z, Kang YJ, Nakanishi N, Okamoto S, Roberts AJ, Schwarz JJ, Lipton SA. Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 9397-402. PMID 18599437 DOI: 10.1073/Pnas.0802876105 |
0.774 |
|
| 2008 |
Li Z, McKercher SR, Cui J, Nie Z, Soussou W, Roberts AJ, Sallmen T, Lipton JH, Talantova M, Okamoto S, Lipton SA. Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6557-68. PMID 18579729 DOI: 10.1523/Jneurosci.0134-08.2008 |
0.745 |
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| 2008 |
Lipton SA. NMDA receptor activity regulates transcription of antioxidant pathways. Nature Neuroscience. 11: 381-2. PMID 18368041 DOI: 10.1038/nn0408-381 |
0.406 |
|
| 2008 |
Tong G, Takahashi H, Tu S, Shin Y, Talantova M, Zago W, Xia P, Nie Z, Goetz T, Zhang D, Lipton SA, Nakanishi N. Modulation of NMDA receptor properties and synaptic transmission by the NR3A subunit in mouse hippocampal and cerebrocortical neurons. Journal of Neurophysiology. 99: 122-32. PMID 18003876 DOI: 10.1152/jn.01044.2006 |
0.62 |
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| 2008 |
Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, Kitajima C, Cui J, Kamins J, Okamoto S, Izumi M, Shirasawa T, Lipton SA. Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. Journal of Neurochemistry. 104: 1116-31. PMID 17995931 DOI: 10.1111/J.1471-4159.2007.05039.X |
0.35 |
|
| 2008 |
Nakagomi S, Barsoum MJ, Bossy-Wetzel E, Sütterlin C, Malhotra V, Lipton SA. A Golgi fragmentation pathway in neurodegeneration. Neurobiology of Disease. 29: 221-31. PMID 17964175 DOI: 10.1016/J.Nbd.2007.08.015 |
0.348 |
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| 2008 |
Nakamura T, Lipton SA. Emerging roles of S-nitrosylation in protein misfolding and neurodegenerative diseases. Antioxidants & Redox Signaling. 10: 87-101. PMID 17961071 DOI: 10.1089/ars.2007.1858 |
0.404 |
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| 2007 |
Fang J, Nakamura T, Cho DH, Gu Z, Lipton SA. S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 18742-7. PMID 18003920 DOI: 10.1073/Pnas.0705904104 |
0.33 |
|
| 2007 |
Stys PK, Lipton SA. White matter NMDA receptors: an unexpected new therapeutic target? Trends in Pharmacological Sciences. 28: 561-6. PMID 17961731 DOI: 10.1016/J.Tips.2007.10.003 |
0.339 |
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| 2007 |
Alirezaei M, Watry DD, Flynn CF, Kiosses WB, Masliah E, Williams BR, Kaul M, Lipton SA, Fox HS. Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11047-55. PMID 17928446 DOI: 10.1523/Jneurosci.2733-07.2007 |
0.377 |
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| 2007 |
Lipton SA. Pathologically activated therapeutics for neuroprotection. Nature Reviews. Neuroscience. 8: 803-8. PMID 17882256 DOI: 10.1038/nrn2229 |
0.358 |
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| 2007 |
Lipton SA, Gu Z, Nakamura T. Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders. International Review of Neurobiology. 82: 1-27. PMID 17678953 DOI: 10.1016/S0074-7742(07)82001-0 |
0.445 |
|
| 2007 |
Redmond DE, Bjugstad KB, Teng YD, Ourednik V, Ourednik J, Wakeman DR, Parsons XH, Gonzalez R, Blanchard BC, Kim SU, Gu Z, Lipton SA, Markakis EA, Roth RH, Elsworth JD, et al. Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 12175-80. PMID 17586681 DOI: 10.1073/Pnas.0704091104 |
0.314 |
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| 2007 |
Lipton SA. Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation. Current Drug Targets. 8: 621-32. PMID 17504105 DOI: 10.2174/138945007780618472 |
0.422 |
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| 2007 |
Nakamura T, Lipton SA. S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfolding. Cell Death and Differentiation. 14: 1305-14. PMID 17431424 DOI: 10.1038/sj.cdd.4402138 |
0.411 |
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| 2007 |
Nakamura T, Gu Z, Lipton SA. Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases. Aging Cell. 6: 351-9. PMID 17388798 DOI: 10.1111/J.1474-9726.2007.00284.X |
0.311 |
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| 2007 |
Lee JP, Jeyakumar M, Gonzalez R, Takahashi H, Lee PJ, Baek RC, Clark D, Rose H, Fu G, Clarke J, McKercher S, Meerloo J, Muller FJ, Park KI, Butters TD, ... ... Lipton SA, et al. Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. Nature Medicine. 13: 439-47. PMID 17351625 DOI: 10.1038/Nm1548 |
0.352 |
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| 2007 |
Berliocchi L, Corasaniti MT, Bagetta G, Lipton SA. Neuroinflammation in neuronal degeneration and repair. Cell Death and Differentiation. 14: 883-4. PMID 17256010 DOI: 10.1038/sj.cdd.4402097 |
0.308 |
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| 2007 |
Choi WT, Kaul M, Kumar S, Wang J, Kumar IM, Dong CZ, An J, Lipton SA, Huang Z. Neuronal apoptotic signaling pathways probed and intervened by synthetically and modularly modified (SMM) chemokines. The Journal of Biological Chemistry. 282: 7154-63. PMID 17218311 DOI: 10.1074/Jbc.M611599200 |
0.377 |
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| 2007 |
Takahashi H, Shin Y, Cho SJ, Zago WM, Nakamura T, Gu Z, Ma Y, Furukawa H, Liddington R, Zhang D, Tong G, Chen HS, Lipton SA. Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif. Neuron. 53: 53-64. PMID 17196530 DOI: 10.1016/J.Neuron.2006.11.023 |
0.309 |
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| 2007 |
Satoh T, Lipton SA. Redox regulation of neuronal survival mediated by electrophilic compounds. Trends in Neurosciences. 30: 37-45. PMID 17137643 DOI: 10.1016/j.tins.2006.11.004 |
0.304 |
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| 2007 |
Yuan H, Gerencser AA, Liot G, Lipton SA, Ellisman M, Perkins GA, Bossy-Wetzel E. Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons. Cell Death and Differentiation. 14: 462-71. PMID 17053808 DOI: 10.1038/Sj.Cdd.4402046 |
0.31 |
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| 2007 |
Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors. Molecular Pharmacology. 71: 112-22. PMID 17047094 DOI: 10.1124/mol.106.030700 |
0.345 |
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| 2007 |
Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA. HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death and Differentiation. 14: 296-305. PMID 16841089 DOI: 10.1038/Sj.Cdd.4402006 |
0.367 |
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| 2006 |
Kaul M, Lipton SA. Mechanisms of neuroimmunity and neurodegeneration associated with HIV-1 infection and AIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 138-51. PMID 18040780 DOI: 10.1007/S11481-006-9011-9 |
0.318 |
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| 2006 |
Wada A, Takahashi H, Lipton SA, Chen HS. NR3A modulates the outer vestibule of the "NMDA" receptor channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13156-66. PMID 17182766 DOI: 10.1523/JNEUROSCI.2552-06.2006 |
0.309 |
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| 2006 |
Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Gräber S, Kovacs I, Lee WD, Waggoner J, Cui J, White AD, Bossy B, Martinou JC, Youle RJ, Lipton SA, et al. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. The Embo Journal. 25: 3900-11. PMID 16874299 DOI: 10.1038/Sj.Emboj.7601253 |
0.353 |
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| 2006 |
Wang Y, Eu J, Washburn M, Gong T, Chen HS, James WL, Lipton SA, Stamler JS, Went GT, Porter S. The pharmacology of aminoadamantane nitrates. Current Alzheimer Research. 3: 201-4. PMID 16842096 DOI: 10.2174/156720506777632808 |
0.371 |
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| 2006 |
Kaul M, Lipton SA. Mechanisms of neuronal injury and death in HIV-1 associated dementia. Current Hiv Research. 4: 307-18. PMID 16842083 DOI: 10.2174/157016206777709384 |
0.331 |
|
| 2006 |
Chen HS, Lipton SA. The chemical biology of clinically tolerated NMDA receptor antagonists. Journal of Neurochemistry. 97: 1611-26. PMID 16805772 DOI: 10.1111/j.1471-4159.2006.03991.x |
0.424 |
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| 2006 |
Uehara T, Nakamura T, Yao D, Shi ZQ, Gu Z, Ma Y, Masliah E, Nomura Y, Lipton SA. S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature. 441: 513-7. PMID 16724068 DOI: 10.1038/Nature04782 |
0.33 |
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| 2006 |
Lipton SA. NMDA receptors, glial cells, and clinical medicine. Neuron. 50: 9-11. PMID 16600850 DOI: 10.1016/j.neuron.2006.03.026 |
0.376 |
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| 2006 |
Lipton SA. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nature Reviews. Drug Discovery. 5: 160-70. PMID 16424917 DOI: 10.1038/nrd1958 |
0.379 |
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| 2006 |
Satoh T, Okamoto SI, Cui J, Watanabe Y, Furuta K, Suzuki M, Tohyama K, Lipton SA. Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proceedings of the National Academy of Sciences of the United States of America. 103: 768-73. PMID 16407140 DOI: 10.1073/pnas.0505723102 |
0.372 |
|
| 2005 |
Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11542-52. PMID 16354912 DOI: 10.1523/Jneurosci.3831-05.2005 |
0.365 |
|
| 2005 |
Manabe S, Gu Z, Lipton SA. Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death. Investigative Ophthalmology & Visual Science. 46: 4747-53. PMID 16303975 DOI: 10.1167/Iovs.05-0128 |
0.403 |
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| 2005 |
Kaul M, Lipton SA. Experimental and potential future therapeutic approaches for HIV-1 associated dementia targeting receptors for chemokines, glutamate and erythropoietin. Neurotoxicity Research. 8: 167-86. PMID 16260394 DOI: 10.1007/Bf03033828 |
0.359 |
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| 2005 |
Gu Z, Cui J, Brown S, Fridman R, Mobashery S, Strongin AY, Lipton SA. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6401-8. PMID 16000631 DOI: 10.1523/Jneurosci.1563-05.2005 |
0.301 |
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| 2005 |
Lipton SA. The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism. Current Alzheimer Research. 2: 155-65. PMID 15974913 DOI: 10.2174/1567205053585846 |
0.419 |
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| 2005 |
Chen HS, Lipton SA. Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels. The Journal of Pharmacology and Experimental Therapeutics. 314: 961-71. PMID 15901795 DOI: 10.1124/jpet.105.085142 |
0.307 |
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| 2005 |
Brody SA, Nakanishi N, Tu S, Lipton SA, Geyer MA. A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle. Biological Psychiatry. 57: 1147-52. PMID 15866554 DOI: 10.1016/J.Biopsych.2005.01.024 |
0.368 |
|
| 2005 |
Kaul M, Zheng J, Okamoto S, Gendelman HE, Lipton SA. HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death and Differentiation. 12: 878-92. PMID 15832177 DOI: 10.1038/Sj.Cdd.4401623 |
0.344 |
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| 2004 |
Lipton SA. Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 101-10. PMID 15717010 DOI: 10.1602/neurorx.1.1.101 |
0.418 |
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| 2004 |
Lipton SA. Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurologic disorders. Journal of Alzheimer's Disease : Jad. 6: S61-74. PMID 15665416 DOI: 10.3233/Jad-2004-6S610 |
0.419 |
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| 2004 |
Chae HJ, Kim HR, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S, Banares S, Cui J, Digicaylioglu M, Ke N, Kitada S, Monosov E, Thomas M, Kress CL, Babendure JR, ... ... Lipton SA, et al. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Molecular Cell. 15: 355-66. PMID 15304216 DOI: 10.1016/J.Molcel.2004.06.038 |
0.311 |
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| 2004 |
Yao D, Gu Z, Nakamura T, Shi ZQ, Ma Y, Gaston B, Palmer LA, Rockenstein EM, Zhang Z, Masliah E, Uehara T, Lipton SA. Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 10810-4. PMID 15252205 DOI: 10.1073/Pnas.0404161101 |
0.332 |
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| 2004 |
Digicaylioglu M, Garden G, Timberlake S, Fletcher L, Lipton SA. Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I. Proceedings of the National Academy of Sciences of the United States of America. 101: 9855-60. PMID 15210945 DOI: 10.1073/pnas.0403172101 |
0.623 |
|
| 2004 |
Digicaylioglu M, Kaul M, Fletcher L, Dowen R, Lipton SA. Erythropoietin protects cerebrocortical neurons from HIV-1/gp120-induced damage. Neuroreport. 15: 761-3. PMID 15073510 DOI: 10.1097/00001756-200404090-00004 |
0.324 |
|
| 2004 |
Kaul M, Lipton SA. Signaling pathways to neuronal damage and apoptosis in human immunodeficiency virus type 1-associated dementia: Chemokine receptors, excitotoxicity, and beyond. Journal of Neurovirology. 10: 97-101. PMID 14982746 DOI: 10.1080/753312759 |
0.374 |
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| 2004 |
Bossy-Wetzel E, Talantova MV, Lee WD, Schölzke MN, Harrop A, Mathews E, Götz T, Han J, Ellisman MH, Perkins GA, Lipton SA. Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels. Neuron. 41: 351-65. PMID 14766175 DOI: 10.1016/S0896-6273(04)00015-7 |
0.367 |
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| 2004 |
Lipton SA, Chen HS. Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine. Cell Death and Differentiation. 11: 18-20. PMID 14647237 DOI: 10.1038/sj.cdd.4401344 |
0.336 |
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| 2003 |
Kermer P, Digicaylioglu MH, Kaul M, Zapata JM, Krajewska M, Stenner-Liewen F, Takayama S, Krajewski S, Lipton SA, Reed JC. BAG1 over-expression in brain protects against stroke. Brain Pathology (Zurich, Switzerland). 13: 495-506. PMID 14655755 DOI: 10.1111/J.1750-3639.2003.Tb00480.X |
0.365 |
|
| 2003 |
Cui J, Ma YP, Lipton SA, Pan ZH. Glycine receptors and glycinergic synaptic input at the axon terminals of mammalian retinal rod bipolar cells. The Journal of Physiology. 553: 895-909. PMID 14514876 DOI: 10.1113/jphysiol.2003.052092 |
0.305 |
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| 2003 |
Sucher NJ, Kohler K, Tenneti L, Wong HK, Gründer T, Fauser S, Wheeler-Schilling T, Nakanishi N, Lipton SA, Guenther E. N-methyl-D-aspartate receptor subunit NR3A in the retina: developmental expression, cellular localization, and functional aspects. Investigative Ophthalmology & Visual Science. 44: 4451-6. PMID 14507892 DOI: 10.1167/iovs.02-1259 |
0.389 |
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| 2003 |
Lipton SA. Possible role for memantine in protecting retinal ganglion cells from glaucomatous damage. Survey of Ophthalmology. 48: S38-46. PMID 12852433 DOI: 10.1016/S0039-6257(03)00008-0 |
0.429 |
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| 2003 |
Zhao C, Ma H, Bossy-Wetzel E, Lipton SA, Zhang Z, Feng GS. GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2. The Journal of Biological Chemistry. 278: 34641-53. PMID 12819203 DOI: 10.1074/Jbc.M304594200 |
0.308 |
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| 2003 |
Manabe S, Lipton SA. Divergent NMDA signals leading to proapoptotic and antiapoptotic pathways in the rat retina. Investigative Ophthalmology & Visual Science. 44: 385-92. PMID 12506100 DOI: 10.1167/iovs.02-0187 |
0.36 |
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| 2002 |
Okamoto S, Sherman K, Bai G, Lipton SA. Effect of the ubiquitous transcription factors, SP1 and MAZ, on NMDA receptor subunit type 1 (NR1) expression during neuronal differentiation. Brain Research. Molecular Brain Research. 107: 89-96. PMID 12425938 DOI: 10.1016/S0169-328X(02)00440-0 |
0.386 |
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| 2002 |
Wong HK, Liu XB, Matos MF, Chan SF, Pérez-Otaño I, Boysen M, Cui J, Nakanishi N, Trimmer JS, Jones EG, Lipton SA, Sucher NJ. Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain. The Journal of Comparative Neurology. 450: 303-17. PMID 12209845 DOI: 10.1002/cne.10314 |
0.349 |
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| 2002 |
Gu Z, Kaul M, Yan B, Kridel SJ, Cui J, Strongin A, Smith JW, Liddington RC, Lipton SA. S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. Science (New York, N.Y.). 297: 1186-90. PMID 12183632 DOI: 10.1126/Science.1073634 |
0.317 |
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| 2002 |
Lipton SA, Choi YB, Takahashi H, Zhang D, Li W, Godzik A, Bankston LA. Cysteine regulation of protein function--as exemplified by NMDA-receptor modulation. Trends in Neurosciences. 25: 474-80. PMID 12183209 DOI: 10.1016/S0166-2236(02)02245-2 |
0.303 |
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| 2002 |
Garden GA, Budd SL, Tsai E, Hanson L, Kaul M, D'Emilia DM, Friedlander RM, Yuan J, Masliah E, Lipton SA. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4015-24. PMID 12019321 DOI: 10.1523/Jneurosci.22-10-04015.2002 |
0.652 |
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| 2002 |
Sasaki YF, Rothe T, Premkumar LS, Das S, Cui J, Talantova MV, Wong HK, Gong X, Chan SF, Zhang D, Nakanishi N, Sucher NJ, Lipton SA. Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons. Journal of Neurophysiology. 87: 2052-63. PMID 11929923 DOI: 10.1152/jn.00531.2001 |
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| 2002 |
Okamoto S, Li Z, Ju C, Scholzke MN, Mathews E, Cui J, Salvesen GS, Bossy-Wetzel E, Lipton SA. Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 99: 3974-9. PMID 11904443 DOI: 10.1073/Pnas.022036399 |
0.4 |
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| 2002 |
Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature. 415: 793-8. PMID 11823786 DOI: 10.1038/nature715 |
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| 2001 |
Le DA, Lipton SA. Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging. Drugs & Aging. 18: 717-24. PMID 11735619 DOI: 10.2165/00002512-200118100-00001 |
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| 2001 |
Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature. 412: 641-7. PMID 11493922 DOI: 10.1038/35088074 |
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| 2001 |
Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature. 410: 988-94. PMID 11309629 DOI: 10.1038/35073667 |
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| 2001 |
Zhang D, Pan ZH, Awobuluyi M, Lipton SA. Structure and function of GABA(C) receptors: a comparison of native versus recombinant receptors. Trends in Pharmacological Sciences. 22: 121-32. PMID 11239575 DOI: 10.1016/S0165-6147(00)01625-4 |
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| 2001 |
Choi Y, Chen HV, Lipton SA. Three pairs of cysteine residues mediate both redox and zn2+ modulation of the nmda receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 392-400. PMID 11160420 DOI: 10.1523/Jneurosci.21-02-00392.2001 |
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| 2001 |
Perez-Otano I, Schulteis CT, Contractor A, Lipton SA, Trimmer JS, Sucher NJ, Heinemann SF. Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1228-37. PMID 11160393 DOI: 10.1523/Jneurosci.21-04-01228.2001 |
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| 2001 |
Traynelis SF, Lipton SA. Is tissue plasminogen activator a threat to neurons? Nature Medicine. 7: 17-8. PMID 11135603 DOI: 10.1038/83289 |
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| 2001 |
Lipton S. NO and regulation of NMDA receptor function European Neuropsychopharmacology. 11: S176-S177. DOI: 10.1016/S0924-977X(01)80115-2 |
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| 2000 |
Choi YB, Lipton SA. Redox modulation of the NMDA receptor. Cellular and Molecular Life Sciences : Cmls. 57: 1535-41. PMID 11092448 DOI: 10.1007/Pl00000638 |
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| 2000 |
Kikuchi M, Tenneti L, Lipton SA. Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5037-44. PMID 10864961 DOI: 10.1523/Jneurosci.20-13-05037.2000 |
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| 2000 |
Okamoto S, Krainc D, Sherman K, Lipton SA. Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation. Proceedings of the National Academy of Sciences of the United States of America. 97: 7561-6. PMID 10852968 DOI: 10.1073/Pnas.130502697 |
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| 2000 |
Budd SL, Tenneti L, Lishnak T, Lipton SA. Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 6161-6. PMID 10811898 DOI: 10.1073/pnas.100121097 |
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| 2000 |
Yeh MW, Kaul M, Zheng J, Nottet HS, Thylin M, Gendelman HE, Lipton SA. Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine. Journal of Immunology (Baltimore, Md. : 1950). 164: 4265-70. PMID 10754324 DOI: 10.4049/Jimmunol.164.8.4265 |
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| 2000 |
Tenneti L, Lipton SA. Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. Journal of Neurochemistry. 74: 134-42. PMID 10617114 DOI: 10.1046/j.1471-4159.2000.0740134.x |
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| 2000 |
Choi YB, Tenneti L, Le DA, Ortiz J, Bai G, Chen HS, Lipton SA. Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation. Nature Neuroscience. 3: 15-21. PMID 10607390 DOI: 10.1038/71090 |
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| 1999 |
Budd SL, Lipton SA. Signaling events in NMDA receptor-induced apoptosis in cerebrocortical cultures. Annals of the New York Academy of Sciences. 893: 261-4. PMID 10672244 DOI: 10.1111/J.1749-6632.1999.Tb07832.X |
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| 1999 |
Okamoto S, Sherman K, Lipton SA. Absence of binding activity of neuron-restrictive silencer factor is necessary, but not sufficient for transcription of NMDA receptor subunit type 1 in neuronal cells. Brain Research. Molecular Brain Research. 74: 44-54. PMID 10640675 DOI: 10.1016/S0169-328X(99)00250-8 |
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| 1999 |
Kim WK, Choi YB, Rayudu PV, Das P, Asaad W, Arnelle DR, Stamler JS, Lipton SA. Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO-. Neuron. 24: 461-9. PMID 10571239 DOI: 10.1016/S0896-6273(00)80859-4 |
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| 1999 |
Lipton SA. Neuronal protection and destruction by NO. Cell Death and Differentiation. 6: 943-51. PMID 10556970 DOI: 10.1038/sj.cdd.4400580 |
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| 1999 |
Stieg PE, Sathi S, Warach S, Le DA, Lipton SA. Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat. European Journal of Pharmacology. 375: 115-20. PMID 10443569 DOI: 10.1016/S0014-2999(99)00214-9 |
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| 1999 |
Choi YB, Lipton SA. Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor. Neuron. 23: 171-80. PMID 10402203 DOI: 10.1016/S0896-6273(00)80763-1 |
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| 1999 |
Kaul M, Lipton SA. Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 8212-6. PMID 10393974 DOI: 10.1073/pnas.96.14.8212 |
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| 1999 |
Nicotera P, Lipton SA. Excitotoxins in neuronal apoptosis and necrosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 583-91. PMID 10366188 DOI: 10.1097/00004647-199906000-00001 |
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| 1999 |
D'Emilia DM, Lipton SA. Ratio of S-nitrosohomocyst(e)ine to homocyst(e)ine or other thiols determines neurotoxicity in rat cerebrocortical cultures. Neuroscience Letters. 265: 103-6. PMID 10327179 DOI: 10.1016/S0304-3940(99)00210-4 |
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| 1999 |
Lipton SA. Redox sensitivity of NMDA receptors. Methods in Molecular Biology (Clifton, N.J.). 128: 121-30. PMID 10320978 DOI: 10.1385/1-59259-683-5:121 |
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| 1999 |
Lipton SA, Nakanishi N. Shakespeare in love--with NMDA receptors? Nature Medicine. 5: 270-1. PMID 10086378 DOI: 10.1038/6481 |
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| 1998 |
Budd SL, Lipton SA. Calcium tsunamis: do astrocytes transmit cell death messages via gap junctions during ischemia? Nature Neuroscience. 1: 431-2. PMID 10196536 DOI: 10.1038/2147 |
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| 1998 |
Krainc D, Bai G, Okamoto S, Carles M, Kusiak JW, Brent RN, Lipton SA. Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1. The Journal of Biological Chemistry. 273: 26218-24. PMID 9748305 DOI: 10.1074/Jbc.273.40.26218 |
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| 1998 |
Tenneti L, D'Emilia DM, Troy CM, Lipton SA. Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. Journal of Neurochemistry. 71: 946-59. PMID 9721720 DOI: 10.1046/j.1471-4159.1998.71030946.x |
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Lipton SA, Choi YB, Sucher NJ, Chen HS. Neuroprotective versus neurodestructive effects of NO-related species. Biofactors (Oxford, England). 8: 33-40. PMID 9699006 DOI: 10.1002/Biof.5520080107 |
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| 1998 |
Chen HS, Wang YF, Rayudu PV, Edgecomb P, Neill JC, Segal MM, Lipton SA, Jensen FE. Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation. Neuroscience. 86: 1121-32. PMID 9697119 DOI: 10.1016/S0306-4522(98)00163-8 |
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| 1998 |
Zurakowski D, Vorwerk CK, Gorla M, Kanellopoulos AJ, Chaturvedi N, Grosskreutz CL, Lipton SA, Dreyer EB. Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors. Vision Research. 38: 1489-94. PMID 9667013 DOI: 10.1016/S0042-6989(98)00003-0 |
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| 1998 |
Das S, Sasaki YF, Rothe T, Premkumar LS, Takasu M, Crandall JE, Dikkes P, Conner DA, Rayudu PV, Cheung W, Chen HS, Lipton SA, Nakanishi N. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A. Nature. 393: 377-81. PMID 9620802 DOI: 10.1038/30748 |
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| 1998 |
Lipton SA, Nicotera P. Calcium, free radicals and excitotoxins in neuronal apoptosis. Cell Calcium. 23: 165-71. PMID 9601612 DOI: 10.1016/S0143-4160(98)90115-4 |
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Lipton SA. Neuronal injury associated with HIV-1: approaches to treatment. Annual Review of Pharmacology and Toxicology. 38: 159-77. PMID 9597152 DOI: 10.1146/annurev.pharmtox.38.1.159 |
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| 1998 |
Soriano SG, Wang YF, Lipton SA, Dikkes P, Gutierrez-Ramos JC, Hickey PR. ICAM-1 dependent pathway is not involved in the development of neuronal apoptosis after transient focal cerebral ischemia. Brain Research. 780: 337-41. PMID 9507184 DOI: 10.1016/S0006-8993(97)01298-5 |
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Lipton SA, Nicotera P. Excitotoxicity, free radicals, necrosis, and apoptosis Neuroscientist. 4: 345-352. DOI: 10.1177/107385849800400516 |
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Le D, Das S, Wang YF, Yoshizawa T, Sasaki YF, Takasu M, Nemes A, Mendelsohn M, Dikkes P, Lipton SA, Nakanishi N. Enhanced neuronal death from focal ischemia in AMPA-receptor transgenic mice. Brain Research. Molecular Brain Research. 52: 235-41. PMID 9495544 DOI: 10.1016/S0169-328X(97)00261-1 |
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Sucher NJ, Lipton SA, Dreyer EB. Molecular basis of glutamate toxicity in retinal ganglion cells. Vision Research. 37: 3483-93. PMID 9425525 DOI: 10.1016/S0042-6989(97)00047-3 |
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Tenneti L, D'Emilia DM, Lipton SA. Suppression of neuronal apoptosis by S-nitrosylation of caspases. Neuroscience Letters. 236: 139-42. PMID 9406756 DOI: 10.1016/S0304-3940(97)00780-5 |
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Lipton SA. Neuropathogenesis of acquired immunodeficiency syndrome dementia. Current Opinion in Neurology. 10: 247-53. PMID 9229134 DOI: 10.1097/00019052-199706000-00014 |
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Lipton SA, Kim WK, Choi YB, Kumar S, D'Emilia DM, Rayudu PV, Arnelle DR, Stamler JS. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 5923-8. PMID 9159176 DOI: 10.1073/Pnas.94.11.5923 |
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Chen HS, Lipton SA. Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. The Journal of Physiology. 499: 27-46. PMID 9061638 DOI: 10.1113/Jphysiol.1997.Sp021909 |
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Lipton SA. Janus faces of NF-kappa B: neurodestruction versus neuroprotection. Nature Medicine. 3: 20-2. PMID 8986730 DOI: 10.1038/nm0197-20 |
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Lipton SA. AIDS dementia as a form of excitotoxicity: potential therapy with NMDA open-channel blockers and redox congeners of nitric oxide Electroencephalography and Clinical Neurophysiology. 102: P2. DOI: 10.1016/S0013-4694(97)86208-6 |
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Lipton SA. 60 – NO-Related Species: Neuroprotection versus Neurodestruction Primer On Cerebrovascular Diseases. 210-213. DOI: 10.1016/B978-012743170-3.50061-3 |
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| 1996 |
Bonfoco E, Zhivotovsky B, Rossi AD, Aguilar-Santelises M, Orrenius S, Lipton SA, Nicotera P. BCL-2 delay apoptosis and PARP cleavage induced by NO donors in GT1-7 cells. Neuroreport. 8: 273-6. PMID 9051794 DOI: 10.1097/00001756-199612200-00054 |
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| 1996 |
Pan ZH, Segal MM, Lipton SA. Nitric oxide-related species inhibit evoked neurotransmission but enhance spontaneous miniature synaptic currents in central neuronal cultures. Proceedings of the National Academy of Sciences of the United States of America. 93: 15423-8. PMID 8986827 DOI: 10.1073/Pnas.93.26.15423 |
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| 1996 |
Sucher NJ, Awobuluyi M, Choi YB, Lipton SA. NMDA receptors: from genes to channels. Trends in Pharmacological Sciences. 17: 348-55. PMID 8979769 DOI: 10.1016/S0165-6147(96)10046-8 |
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Lipton SA. Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species. Brain Pathology (Zurich, Switzerland). 6: 507-17. PMID 8944320 DOI: 10.1111/J.1750-3639.1996.Tb00879.X |
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| 1996 |
Bonfoco E, Leist M, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P. Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation. Journal of Neurochemistry. 67: 2484-93. PMID 8931482 DOI: 10.1046/J.1471-4159.1996.67062484.X |
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Lipton SA, Choi YB, Sucher NJ, Pan ZH, Stamler JS. Redox state, NMDA receptors and NO-related species. Trends in Pharmacological Sciences. 17: 186-7;discussion 187. PMID 8669124 DOI: 10.1016/0165-6147(96)20028-8 |
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Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 114: 299-305. PMID 8600890 DOI: 10.1001/Archopht.1996.01100130295012 |
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Lipton SA. Neuronal apoptosis versus necrosis induced by glutamate or free radicals Apoptosis. 1: 5-10. DOI: 10.1007/Bf00142073 |
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| 1995 |
Dreyer EB, Lipton SA. The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid. The European Journal of Neuroscience. 7: 2502-7. PMID 8845955 DOI: 10.1111/j.1460-9568.1995.tb01048.x |
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| 1995 |
Pan ZH, Bähring R, Grantyn R, Lipton SA. Differential modulation by sulfhydryl redox agents and glutathione of GABA- and glycine-evoked currents in rat retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1384-91. PMID 7869105 DOI: 10.1523/Jneurosci.15-02-01384.1995 |
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| 1995 |
Pan ZH, Lipton SA. Multiple GABA receptor subtypes mediate inhibition of calcium influx at rat retinal bipolar cell terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2668-79. PMID 7722621 DOI: 10.1523/Jneurosci.15-04-02668.1995 |
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| 1995 |
Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME. N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience. 64: 653-64. PMID 7715778 DOI: 10.1016/0306-4522(94)00462-E |
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| 1995 |
Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proceedings of the National Academy of Sciences of the United States of America. 92: 7162-6. PMID 7638161 DOI: 10.1073/Pnas.92.16.7162 |
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Dreyer EB, Zhang D, Lipton SA. Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death. Neuroreport. 6: 942-4. PMID 7612888 DOI: 10.1097/00001756-199504190-00029 |
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Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15: 961-73. PMID 7576644 DOI: 10.1016/0896-6273(95)90186-8 |
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Kater SB, Lipton SA. Neurotransmitter regulation of neuronal outgrowth, plasticity and survival in the year 2001. Trends in Neurosciences. 18: 71-2. PMID 7537415 DOI: 10.1016/0166-2236(95)80025-W |
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| 1995 |
Dreyer EB, Leifer D, Heng JE, McConnell JE, Gorla M, Levin LA, Barnstable CJ, Lipton SA. An astrocytic binding site for neuronal Thy-1 and its effect on neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 92: 11195-9. PMID 7479964 DOI: 10.1073/pnas.92.24.11195 |
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| 1995 |
Zhang D, Sucher NJ, Lipton SA. Co-expression of AMPA/kainate receptor-operated channels with high and low Ca2+ permeability in single rat retinal ganglion cells. Neuroscience. 67: 177-88. PMID 7477898 DOI: 10.1016/0306-4522(94)00627-H |
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| 1994 |
Lipton SA. HIV-related neuronal injury. Potential therapeutic intervention with calcium channel antagonists and NMDA antagonists. Molecular Neurobiology. 8: 181-96. PMID 7999315 DOI: 10.1007/BF02780669 |
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Dreyer EB, Pan ZH, Storm S, Lipton SA. Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death. Neuroreport. 5: 629-31. PMID 7912962 DOI: 10.1097/00001756-199401000-00024 |
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| 1994 |
Lipton SA, Rosenberg PA. Excitatory amino acids as a final common pathway for neurologic disorders. The New England Journal of Medicine. 330: 613-22. PMID 7905600 DOI: 10.1056/NEJM199403033300907 |
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Lipton SA, Singel DJ, Stamler JS. Nitric oxide in the central nervous system. Progress in Brain Research. 103: 359-64. PMID 7886218 DOI: 10.1016/S0079-6123(08)61149-8 |
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Lipton SA, Yeh M, Dreyer EB. Update on current models of HIV-related neuronal injury: platelet-activating factor, arachidonic acid and nitric oxide. Advances in Neuroimmunology. 4: 181-8. PMID 7874385 DOI: 10.1016/S0960-5428(06)80255-X |
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Lipton SA, Stamler JS. Actions of redox-related congeners of nitric oxide at the NMDA receptor. Neuropharmacology. 33: 1229-33. PMID 7870283 DOI: 10.1016/0028-3908(94)90021-3 |
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Lipton SA. AIDS-related dementia and calcium homeostasis. Annals of the New York Academy of Sciences. 747: 205-24. PMID 7847672 DOI: 10.1111/j.1749-6632.1994.tb44411.x |
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Lipton SA. Ca2+, N-methyl-D-aspartate receptors, and AIDS-related neuronal injury. International Review of Neurobiology. 36: 1-27. PMID 7822116 DOI: 10.1016/S0074-7742(08)60301-3 |
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Lipton SA. Neuronal injury associated with HIV-1 and potential treatment with calcium-channel and NMDA antagonists. Developmental Neuroscience. 16: 145-51. PMID 7705221 DOI: 10.1159/000112101 |
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Sullivan JM, Traynelis SF, Chen HS, Escobar W, Heinemann SF, Lipton SA. Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron. 13: 929-36. PMID 7524561 DOI: 10.1016/0896-6273(94)90258-5 |
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Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 364: 626-32. PMID 8394509 DOI: 10.1038/364626A0 |
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Pellegrini JW, Lipton SA. Delayed administration of memantine prevents N-methyl-D-aspartate receptor-mediated neurotoxicity. Annals of Neurology. 33: 403-7. PMID 8098195 DOI: 10.1002/ana.410330414 |
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Lipton SA. Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide. Trends in Neurosciences. 16: 527-32. PMID 7509524 DOI: 10.1016/0166-2236(93)90198-U |
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| 1992 |
Lipton SA. 7-Chlorokynurenate Ameliorates Neuronal Injury Mediated by HIV Envelope Protein gp120 in Rodent Retinal Cultures. The European Journal of Neuroscience. 4: 1411-1415. PMID 12106405 DOI: 10.1111/j.1460-9568.1992.tb00167.x |
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Lipton SA. Memantine prevents HIV coat protein-induced neuronal injury in vitro. Neurology. 42: 1403-5. PMID 1620355 DOI: 10.1212/Wnl.42.7.1403 |
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| 1992 |
Lei SZ, Zhang D, Abele AE, Lipton SA. Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity. Brain Research. 598: 196-202. PMID 1486480 DOI: 10.1016/0006-8993(92)90183-A |
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Chen HS, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, Lipton SA. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4427-36. PMID 1432103 DOI: 10.1523/Jneurosci.12-11-04427.1992 |
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Lipton SA. Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120. Neuroreport. 3: 913-5. PMID 1421098 DOI: 10.1097/00001756-199210000-00023 |
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Frosch MP, Lipton SA, Dichter MA. Desensitization of GABA-activated currents and channels in cultured cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3042-53. PMID 1379634 DOI: 10.1523/Jneurosci.12-08-03042.1992 |
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| 1992 |
Lei SZ, Pan ZH, Aggarwal SK, Chen HS, Hartman J, Sucher NJ, Lipton SA. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron. 8: 1087-99. PMID 1376999 DOI: 10.1016/0896-6273(92)90130-6 |
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Lipton SA. Models of neuronal injury in AIDS: another role for the NMDA receptor? Trends in Neurosciences. 15: 75-9. PMID 1373919 DOI: 10.1016/0166-2236(92)90013-X |
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| 1992 |
Zhang D, Lipton SA. L-homocysteic acid selectively activates N-methyl-D-aspartate receptors of rat retinal ganglion cells. Neuroscience Letters. 139: 173-7. PMID 1351663 DOI: 10.1016/0304-3940(92)90545-I |
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| 1991 |
Budson AE, Jackson PS, Lipton SA. GDP beta S antagonizes whole-cell current responses to excitatory amino acids. Brain Research. 548: 346-8. PMID 1868345 DOI: 10.1016/0006-8993(91)91147-S |
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Levy DI, Sucher NJ, Lipton SA. Glutathione prevents N-methyl-D-aspartate receptor-mediated neurotoxicity. Neuroreport. 2: 345-7. PMID 1832987 DOI: 10.1097/00001756-199106000-00011 |
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| 1991 |
Sucher NJ, Cheng TP, Lipton SA. Cryopreservation of postnatal rat retinal ganglion cells: persistence of voltage- and ligand-gated ionic currents. Neuroscience. 43: 135-50. PMID 1717883 DOI: 10.1016/0306-4522(91)90423-L |
0.307 |
|
| 1991 |
Sucher NJ, Lei SZ, Lipton SA. Calcium channel antagonists attenuate NMDA receptor-mediated neurotoxicity of retinal ganglion cells in culture. Brain Research. 551: 297-302. PMID 1680525 DOI: 10.1016/0006-8993(91)90944-Q |
0.386 |
|
| 1991 |
Lipton SA, Sucher NJ, Kaiser PK, Dreyer EB. Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron. 7: 111-8. PMID 1676893 DOI: 10.1016/0896-6273(91)90079-F |
0.404 |
|
| 1991 |
Sucher NJ, Aizenman E, Lipton SA. N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 966-71. PMID 1672708 DOI: 10.1523/Jneurosci.11-04-00966.1991 |
0.633 |
|
| 1991 |
Lipton SA. HIV-related neurotoxicity. Brain Pathology (Zurich, Switzerland). 1: 193-9. PMID 1669708 DOI: 10.1111/j.1750-3639.1991.tb00659.x |
0.403 |
|
| 1991 |
Sucher NJ, Lipton SA. Redox modulatory site of the NMDA receptor-channel complex: regulation by oxidized glutathione. Journal of Neuroscience Research. 30: 582-91. PMID 1666131 DOI: 10.1002/jnr.490300316 |
0.407 |
|
| 1991 |
Lipton SA. Calcium channel antagonists and human immunodeficiency virus coat protein-mediated neuronal injury. Annals of Neurology. 30: 110-4. PMID 1656845 DOI: 10.1002/ana.410300121 |
0.349 |
|
| 1990 |
Aizenman E, Loring RH, Lipton SA. Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin. Brain Research. 517: 209-14. PMID 2375991 DOI: 10.1016/0006-8993(90)91028-F |
0.588 |
|
| 1990 |
Dreyer EB, Kaiser PK, Offermann JT, Lipton SA. HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists Science. 248: 364-367. PMID 2326646 DOI: 10.1126/Science.2326646 |
0.31 |
|
| 1990 |
Sucher NJ, Cheng TP, Lipton SA. Neural nicotinic acetylcholine responses in sensory neurons from postnatal rat. Brain Research. 533: 248-54. PMID 2289141 DOI: 10.1016/0006-8993(90)91346-I |
0.323 |
|
| 1990 |
Kaiser PK, Offermann JT, Lipton SA. Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. Neurology. 40: 1757-61. PMID 2234433 DOI: 10.1212/Wnl.40.11.1757 |
0.306 |
|
| 1990 |
Kaiser PK, Lipton SA. VIP-mediated increase in cAMP prevents tetrodotoxin-induced retinal ganglion cell death in vitro. Neuron. 5: 373-81. PMID 2169272 DOI: 10.1016/0896-6273(90)90173-D |
0.339 |
|
| 1990 |
Sucher NJ, Wong LA, Lipton SA. Redox modulation of NMDA receptor-mediated Ca2+ flux in mammalian central neurons. Neuroreport. 1: 29-32. PMID 2151794 DOI: 10.1097/00001756-199009000-00009 |
0.353 |
|
| 1990 |
Levy DI, Lipton SA. Comparison of delayed administration of competitive and uncompetitive antagonists in preventing NMDA receptor-mediated neuronal death Neurology. 40: 852-855. PMID 1970428 DOI: 10.1212/Wnl.40.5.852 |
0.433 |
|
| 1990 |
Levy DI, Sucher NJ, Lipton SA. Redox modulation of NMDA receptor-mediated toxicity in mammalian central neurons Neuroscience Letters. 110: 291-296. PMID 1970145 DOI: 10.1016/0304-3940(90)90862-4 |
0.448 |
|
| 1989 |
Loring RH, Aizenman E, Lipton SA, Zigmond RE. Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 2423-31. PMID 2746336 DOI: 10.1523/Jneurosci.09-07-02423.1989 |
0.576 |
|
| 1989 |
Aizenman E, Lipton SA, Loring RH. Selective modulation of NMDA responses by reduction and oxidation. Neuron. 2: 1257-63. PMID 2696504 DOI: 10.1016/0896-6273(89)90310-3 |
0.628 |
|
| 1989 |
Aizenman E, Karschin A, Lipton SA. Two pharmacological classes of quisqualate-induced electrical responses in rat retinal ganglion cells in vitro. European Journal of Pharmacology. 174: 9-22. PMID 2575535 DOI: 10.1016/0014-2999(89)90868-6 |
0.584 |
|
| 1989 |
Lipton SA. Growth Factors for Neuronal Survival and Process Regeneration: Implications in the Mammalian Central Nervous System Archives of Neurology. 46: 1241-1248. PMID 2573331 DOI: 10.1001/archneur.1989.00520470113038 |
0.349 |
|
| 1989 |
Karschin A, Lipton SA. Calcium channels in solitary retinal ganglion cells from post-natal rat Journal of Physiology. 418: 379-396. PMID 2559971 DOI: 10.1113/Jphysiol.1989.Sp017847 |
0.312 |
|
| 1989 |
Lipton SA, Kater SB. Neurotransmitter regulation of neuronal outgrowth, plasticity and survival. Trends in Neurosciences. 12: 265-70. PMID 2475939 DOI: 10.1016/0166-2236(89)90026-X |
0.367 |
|
| 1988 |
Lipton SA, Wagner JA, Madison RD, D'Amore PA. Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture Proceedings of the National Academy of Sciences of the United States of America. 85: 2388-2392. PMID 3353388 DOI: 10.1073/Pnas.85.7.2388 |
0.3 |
|
| 1988 |
Lipton SA, Frosch MP, Phillips MD, Tauck DL, Aizenman E. Nicotinic antagonists enhance process outgrowth by rat retinal ganglion cells in culture. Science (New York, N.Y.). 239: 1293-6. PMID 3344435 DOI: 10.1126/Science.3344435 |
0.581 |
|
| 1988 |
Lipton SA. Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture Journal of Neuroscience. 8: 3857-3868. PMID 2903915 DOI: 10.1523/Jneurosci.08-10-03857.1988 |
0.311 |
|
| 1988 |
Hahn JS, Aizenman E, Lipton SA. Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801. Proceedings of the National Academy of Sciences of the United States of America. 85: 6556-60. PMID 2901101 DOI: 10.1073/Pnas.85.17.6556 |
0.637 |
|
| 1988 |
Aizenman E, Frosch MP, Lipton SA. Responses mediated by excitatory amino acid receptors in solitary retinal ganglion cells from rat. The Journal of Physiology. 396: 75-91. PMID 2842491 DOI: 10.1113/Jphysiol.1988.Sp016951 |
0.598 |
|
| 1988 |
Karschin A, Aizenman E, Lipton SA. The interaction of agonists and noncompetitive antagonists at the excitatory amino acid receptors in rat retinal ganglion cells in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2895-906. PMID 2842467 DOI: 10.1523/Jneurosci.08-08-02895.1988 |
0.621 |
|
| 1987 |
Lipton SA, Aizenman E, Loring RH. Neural nicotinic acetylcholine responses in solitary mammalian retinal ganglion cells. Pflã¼Gers Archiv : European Journal of Physiology. 410: 37-43. PMID 3684508 DOI: 10.1007/Bf00581893 |
0.577 |
|
| 1987 |
Lipton SA. Bursting of calcium-activated cation-selective channels is associated with neurite regeneration in a mammalian central neuron Neuroscience Letters. 82: 21-28. PMID 2447529 DOI: 10.1016/0304-3940(87)90165-0 |
0.335 |
|
| 1986 |
Lipton SA. Blockade of electrical activity promotes the death of mammalian retinal ganglion cells in culture Proceedings of the National Academy of Sciences of the United States of America. 83: 9774-9778. PMID 3025849 DOI: 10.1073/Pnas.83.24.9774 |
0.373 |
|
| 1981 |
Lipton SA, Dowling JE. Chapter 21 The Relation between Ca2+ and Cyclic GMP in Rod Photoreceptors Current Topics in Membranes and Transport. 15: 381-392. DOI: 10.1016/S0070-2161(08)60512-2 |
0.384 |
|
| 1979 |
Lipton SA, Ostroy SE, Dowling JE. Ca2+ and photoreceptor adaptation. Nature. 281: 407-8. PMID 481607 DOI: 10.1038/281407c0 |
0.444 |
|
| 1977 |
Lipton SA, Ostroy SE, Dowling JE. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels. The Journal of General Physiology. 70: 747-70. PMID 412914 DOI: 10.1085/Jgp.70.6.747 |
0.49 |
|
| 1977 |
Lipton SA, Rasmussen H, Dowling JE. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins. The Journal of General Physiology. 70: 771-91. PMID 201724 DOI: 10.1085/Jgp.70.6.771 |
0.493 |
|
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