| Year |
Citation |
Score |
| 2021 |
Belelli D, Hales TG, Lambert JJ, Luscher B, Olsen R, Peters JA, Rudolph U, Sieghart W. GABA receptors in GtoPdb v.2021.3. Iuphar/Bps Guide to Pharmacology Cite. 2021. PMID 35005623 DOI: 10.2218/gtopdb/F72/2021.3 |
0.386 |
|
| 2020 |
Baptista-Hon DT, Smith M, Singleton S, Antonides LH, Nic Daeid N, McKenzie C, Hales TG. Activation of μ opioid receptors by MT-45 and its fluorinated derivatives. British Journal of Pharmacology. PMID 32246840 DOI: 10.1111/Bph.15064 |
0.338 |
|
| 2019 |
Hunter WN, Jones MJ, Dawson A, Hales TG. A structural rationale for N-methylbicuculline acting as a promiscuous competitive antagonist of inhibitory pentameric ligand gated ion channels. Chembiochem : a European Journal of Chemical Biology. PMID 31859406 DOI: 10.1002/Cbic.201900680 |
0.457 |
|
| 2019 |
Dawson A, Trumper P, de Souza JO, Parker H, Jones MJ, Hales TG, Hunter WN. Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj. 6: 1014-1023. PMID 31709057 DOI: 10.1107/S205225251901114X |
0.356 |
|
| 2019 |
Sharma KK, Hales TG, Rao VJ, NicDaeid N, McKenzie C. The search for the "next" euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning. Forensic Toxicology. 37: 1-16. PMID 30636980 DOI: 10.1007/S11419-018-0454-5 |
0.307 |
|
| 2019 |
Davies P, Hales TG, Jensen AA, Peters JA. ZAC (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f83/2019.4 |
0.312 |
|
| 2019 |
Belelli D, Hales TG, Lambert JJ, Luscher B, Olsen R, Peters JA, Rudolph U, Sieghart W. GABAA receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f72/2019.4 |
0.373 |
|
| 2019 |
Barnes NM, Hales TG, Lummis SCR, Niesler B, Peters JA. 5-HT3 receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f68/2019.4 |
0.508 |
|
| 2019 |
Smith M, Baptista-Hon D, Antonides L, McKenzie C, Daeid N, Hales T. Activation of the mu-opioid receptor by MT-45 and its synthetic and metabolic derivatives British Journal of Anaesthesia. 122: e51. DOI: 10.1016/J.Bja.2018.10.047 |
0.343 |
|
| 2019 |
Singleton S, Baptista-Hon D, Bull F, Hales T. Measuring the bias of morphine, oxycodone, and buprenorphine for G protein activation vs β-arrestin2 recruitment to the μ opioid receptor British Journal of Anaesthesia. 122: e48. DOI: 10.1016/J.Bja.2018.10.038 |
0.307 |
|
| 2018 |
Gottschald Chiodi C, Baptista-Hon DT, Hunter WN, Hales TG. Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA. The Journal of Biological Chemistry. PMID 30545943 DOI: 10.1074/Jbc.Ra118.006229 |
0.445 |
|
| 2018 |
Elajnaf T, Baptista-Hon DT, Hales TG. Potent Inactivation-Dependent Inhibition of Adult and Neonatal NaV1.5 Channels by Lidocaine and Levobupivacaine. Anesthesia and Analgesia. PMID 29958221 DOI: 10.1213/Ane.0000000000003597 |
0.32 |
|
| 2016 |
Baptista-Hon DT, Gulbinaite S, Hales TG. Loop G in the GABAA receptor α1 subunit influences gating efficacy. The Journal of Physiology. PMID 27981574 DOI: 10.1113/Jp273752 |
0.438 |
|
| 2016 |
Baptista-Hon DT, Krah A, Zachariae U, Hales TG. A role for loop G in the β1 strand in GABAA receptor activation. The Journal of Physiology. PMID 27195487 DOI: 10.1113/Jp272463 |
0.442 |
|
| 2015 |
House CD, Wang BD, Ceniccola K, Williams R, Simaan M, Olender J, Patel V, Baptista-Hon DT, Annunziata CM, Silvio Gutkind J, Hales TG, Lee NH. Voltage-gated Na(+) Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling. Scientific Reports. 5: 11541. PMID 26096612 DOI: 10.1038/Srep11541 |
0.695 |
|
| 2015 |
Morton RA, Baptista-Hon DT, Hales TG, Lovinger DM. Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors. British Journal of Pharmacology. 172: 4066-77. PMID 25989383 DOI: 10.1111/Bph.13197 |
0.79 |
|
| 2015 |
Vickery ON, Baptista-Hon DT, Seeliger D, Hales TG, Zachariae U. Investigating the Effect of Sodium and Voltage on δ-Opioid Receptors Biophysical Journal. 108: 414a. DOI: 10.1016/J.Bpj.2014.11.2272 |
0.38 |
|
| 2014 |
Baptista-Hon DT, Robertson FM, Robertson GB, Owen SJ, Rogers GW, Lydon EL, Lee NH, Hales TG. Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function. British Journal of Anaesthesia. 113: i39-i48. PMID 24852501 DOI: 10.1093/Bja/Aeu104 |
0.315 |
|
| 2013 |
Carland JE, Cooper MA, Livesey MR, Hales TG, Peters JA, Lambert JJ. Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor. The Journal of Biological Chemistry. 288: 31592-601. PMID 24030822 DOI: 10.1074/Jbc.M113.503300 |
0.502 |
|
| 2013 |
Baptista-Hon DT, Deeb TZ, Lambert JJ, Peters JA, Hales TG. The minimum M3-M4 loop length of neurotransmitter-activated pentameric receptors is critical for the structural integrity of cytoplasmic portals. The Journal of Biological Chemistry. 288: 21558-68. PMID 23740249 DOI: 10.1074/Jbc.M113.481689 |
0.721 |
|
| 2012 |
Othman NA, Gallacher M, Deeb TZ, Baptista-Hon DT, Perry DC, Hales TG. Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization. The Journal of Physiology. 590: 163-78. PMID 22083597 DOI: 10.1113/Jphysiol.2011.213249 |
0.73 |
|
| 2012 |
Baptista-Hon DT, Deeb TZ, Othman NA, Sharp D, Hales TG. The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine. British Journal of Pharmacology. 165: 693-704. PMID 21740409 DOI: 10.1111/J.1476-5381.2011.01582.X |
0.756 |
|
| 2011 |
Lam H, Maga M, Pradhan A, Evans CJ, Maidment NT, Hales TG, Walwyn W. Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2. Molecular Pain. 7: 24. PMID 21486473 DOI: 10.1186/1744-8069-7-24 |
0.459 |
|
| 2011 |
Morton RA, Luo G, Davis MI, Hales TG, Lovinger DM. Fluorophore assisted light inactivation (FALI) of recombinant 5-HT₃A receptor constitutive internalization and function. Molecular and Cellular Neurosciences. 47: 79-92. PMID 21338684 DOI: 10.1016/J.Mcn.2011.02.007 |
0.745 |
|
| 2010 |
House CD, Vaske CJ, Schwartz AM, Obias V, Frank B, Luu T, Sarvazyan N, Irby R, Strausberg RL, Hales TG, Stuart JM, Lee NH. Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion. Cancer Research. 70: 6957-67. PMID 20651255 DOI: 10.1158/0008-5472.Can-10-1169 |
0.694 |
|
| 2010 |
Wu DF, Othman NA, Sharp D, Mahendra A, Deeb TZ, Hales TG. A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function. The Journal of Physiology. 588: 603-16. PMID 19933756 DOI: 10.1113/Jphysiol.2009.181719 |
0.762 |
|
| 2010 |
Peters JA, Cooper MA, Carland JE, Livesey MR, Hales TG, Lambert JJ. Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors. The Journal of Physiology. 588: 587-96. PMID 19933751 DOI: 10.1113/Jphysiol.2009.183137 |
0.426 |
|
| 2010 |
House C, Vaske C, Schwartz A, Obias V, Sarvazyan N, Hales T, Stuart J, Lee N. Abstract 5292: Role of voltage-gated Na+ channels in the metastatic potential of colon cancer cells Cancer Research. 70: 5292-5292. DOI: 10.1158/1538-7445.Am10-5292 |
0.716 |
|
| 2009 |
Walwyn W, John S, Maga M, Evans CJ, Hales TG. Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons. Molecular Pharmacology. 76: 134-43. PMID 19357247 DOI: 10.1124/Mol.109.055913 |
0.486 |
|
| 2009 |
Deeb TZ, Sharp D, Hales TG. Direct subunit-dependent multimodal 5-hydroxytryptamine3 receptor antagonism by methadone. Molecular Pharmacology. 75: 908-17. PMID 19131665 DOI: 10.1124/Mol.108.053322 |
0.771 |
|
| 2009 |
Barnes NM, Hales TG, Lummis SC, Peters JA. The 5-HT3 receptor--the relationship between structure and function. Neuropharmacology. 56: 273-84. PMID 18761359 DOI: 10.1016/J.Neuropharm.2008.08.003 |
0.569 |
|
| 2009 |
Morton RA, Luo G, Davis MI, Hales TG, Lovinger DM. Ethanol and trafficking of 5-HT3A receptors Alcoholism: Clinical and Experimental Research. 33. DOI: 10.1111/J.1530-0277.2009.00957.X |
0.728 |
|
| 2008 |
Livesey MR, Cooper MA, Deeb TZ, Carland JE, Kozuska J, Hales TG, Lambert JJ, Peters JA. Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. The Journal of Biological Chemistry. 283: 19301-13. PMID 18474595 DOI: 10.1074/Jbc.M802406200 |
0.723 |
|
| 2008 |
Bollan KA, Baur R, Hales TG, Sigel E, Connolly CN. The promiscuous role of the epsilon subunit in GABAA receptor biogenesis. Molecular and Cellular Neurosciences. 37: 610-21. PMID 18206389 DOI: 10.1016/J.Mcn.2007.12.011 |
0.409 |
|
| 2008 |
Drisdel RC, Sharp D, Henderson T, Hales TG, Green WN. High affinity binding of epibatidine to serotonin type 3 receptors. The Journal of Biological Chemistry. 283: 9659-65. PMID 17702741 DOI: 10.1074/Jbc.M703672200 |
0.481 |
|
| 2007 |
Walwyn W, Evans CJ, Hales TG. Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5092-104. PMID 17494695 DOI: 10.1523/Jneurosci.1157-07.2007 |
0.404 |
|
| 2007 |
Deeb TZ, Carland JE, Cooper MA, Livesey MR, Lambert JJ, Peters JA, Hales TG. Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor. The Journal of Biological Chemistry. 282: 6172-82. PMID 17200121 DOI: 10.1074/Jbc.M607698200 |
0.757 |
|
| 2007 |
McCartney MR, Deeb TZ, Henderson TN, Hales TG. Tonically active GABAA receptors in hippocampal pyramidal neurons exhibit constitutive GABA-independent gating. Molecular Pharmacology. 71: 539-48. PMID 17090706 DOI: 10.1124/Mol.106.028597 |
0.752 |
|
| 2006 |
Peters JA, Carland JE, Cooper MA, Livesey MR, Deeb TZ, Hales TG, Lambert JJ. Novel structural determinants of single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors. Biochemical Society Transactions. 34: 882-6. PMID 17052220 DOI: 10.1042/Bst0340882 |
0.762 |
|
| 2006 |
Hales TG, Deeb TZ, Tang H, Bollan KA, King DP, Johnson SJ, Connolly CN. An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits. The Journal of Biological Chemistry. 281: 17034-43. PMID 16627470 DOI: 10.1074/Jbc.M603599200 |
0.755 |
|
| 2006 |
Hales TG, Dunlop JI, Deeb TZ, Carland JE, Kelley SP, Lambert JJ, Peters JA. Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 281: 8062-71. PMID 16407231 DOI: 10.1074/Jbc.M513222200 |
0.73 |
|
| 2005 |
Wagner DA, Goldschen-Ohm MP, Hales TG, Jones MV. Kinetics and spontaneous open probability conferred by the epsilon subunit of the GABAA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10462-8. PMID 16280584 DOI: 10.1523/Jneurosci.1658-05.2005 |
0.531 |
|
| 2005 |
Peters JA, Hales TG, Lambert JJ. Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor. Trends in Pharmacological Sciences. 26: 587-94. PMID 16194573 DOI: 10.1016/J.Tips.2005.09.011 |
0.483 |
|
| 2005 |
Walwyn W, Maidment NT, Sanders M, Evans CJ, Kieffer BL, Hales TG. Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons. Molecular Pharmacology. 68: 1688-98. PMID 16135785 DOI: 10.1124/Mol.105.014829 |
0.484 |
|
| 2005 |
Hales TG, Tang H, Bollan KA, Johnson SJ, King DP, McDonald NA, Cheng A, Connolly CN. The epilepsy mutation, gamma2(R43Q) disrupts a highly conserved inter-subunit contact site, perturbing the biogenesis of GABAA receptors. Molecular and Cellular Neurosciences. 29: 120-7. PMID 15866052 DOI: 10.1016/J.Mcn.2005.01.002 |
0.41 |
|
| 2004 |
Charles AC, Hales TG. From inhibition to excitation: functional effects of interaction between opioid receptors. Life Sciences. 76: 479-85. PMID 15556161 DOI: 10.1016/J.Lfs.2004.09.012 |
0.404 |
|
| 2004 |
Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ. The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance. Biochemical Society Transactions. 32: 547-52. PMID 15157181 DOI: 10.1042/Bst0320547 |
0.553 |
|
| 2003 |
Stewart A, Davies PA, Kirkness EF, Safa P, Hales TG. Introduction of the 5-HT3B subunit alters the functional properties of 5-HT3 receptors native to neuroblastoma cells. Neuropharmacology. 44: 214-23. PMID 12623220 DOI: 10.1016/S0028-3908(02)00376-3 |
0.505 |
|
| 2003 |
Charles AC, Mostovskaya N, Asas K, Evans CJ, Dankovich ML, Hales TG. Coexpression of delta-opioid receptors with micro receptors in GH3 cells changes the functional response to micro agonists from inhibitory to excitatory. Molecular Pharmacology. 63: 89-95. PMID 12488540 DOI: 10.1124/Mol.63.1.89 |
0.441 |
|
| 2003 |
Davies PA, Wang W, Hales TG, Kirkness EF. A novel class of ligand-gated ion channel is activated by Zn2+. The Journal of Biological Chemistry. 278: 712-7. PMID 12381728 DOI: 10.1074/Jbc.M208814200 |
0.412 |
|
| 2003 |
Stewart A, Davies PA, Kirkness EF, Safa P, Hales TG. Introduction of the 5-HT 3B subunit alters the functional properties of 5-HT 3 receptors native to neuroblastoma cells Neuropharmacology. 44: 214-223. DOI: 10.1016/S0028-3908(02)00376-3 |
0.411 |
|
| 2002 |
Davies PA, McCartney MR, Wang W, Hales TG, Kirkness EF. Alternative transcripts of the GABA(A) receptor epsilon subunit in human and rat. Neuropharmacology. 43: 467-75. PMID 12367593 DOI: 10.1016/S0028-3908(02)00153-3 |
0.44 |
|
| 2002 |
Irnaten M, Walwyn WM, Wang J, Venkatesan P, Evans C, Chang KS, Andresen MC, Hales TG, Mendelowitz D. Pentobarbital enhances GABAergic neurotransmission to cardiac parasympathetic neurons, which is prevented by expression of GABA(A) epsilon subunit. Anesthesiology. 97: 717-24. PMID 12218540 DOI: 10.1097/00000542-200209000-00027 |
0.401 |
|
| 2002 |
Davies PA, Kirkness EF, Hales TG. Evidence for the formation of functionally distinct alphabetagammaepsilon GABA(A) receptors. The Journal of Physiology. 537: 101-13. PMID 11711565 DOI: 10.1111/J.1469-7793.2001.0101K.X |
0.483 |
|
| 2001 |
Safa P, Boulter J, Hales TG. Functional properties of Cav1.3 (alpha1D) L-type Ca2+ channel splice variants expressed by rat brain and neuroendocrine GH3 cells. The Journal of Biological Chemistry. 276: 38727-37. PMID 11514547 DOI: 10.1074/Jbc.M103724200 |
0.334 |
|
| 2000 |
Hanna MC, Davies PA, Hales TG, Kirkness EF. Evidence for expression of heteromeric serotonin 5-HT(3) receptors in rodents. Journal of Neurochemistry. 75: 240-7. PMID 10854267 DOI: 10.1046/J.1471-4159.2000.0750240.X |
0.549 |
|
| 2000 |
Piros ET, Charles AC, Song L, Evans CJ, Hales TG. Cloned δ-opioid receptors in GH3 cells inhibit spontaneous Ca2+ oscillations and prolactin release through K(IR) channel activation Journal of Neurophysiology. 83: 2691-2698. PMID 10805669 DOI: 10.1152/Jn.2000.83.5.2691 |
0.377 |
|
| 2000 |
Davies PA, Hoffmann EB, Carlisle HJ, Tyndale RF, Hales TG. The influence of an endogenous beta3 subunit on recombinant GABA(A) receptor assembly and pharmacology in WSS-1 cells and transiently transfected HEK293 cells. Neuropharmacology. 39: 611-20. PMID 10728882 DOI: 10.1016/S0028-3908(99)00163-X |
0.46 |
|
| 1999 |
Tian J, Chau C, Hales TG, Kaufman DL. GABA(A) receptors mediate inhibition of T cell responses. Journal of Neuroimmunology. 96: 21-8. PMID 10227421 DOI: 10.1016/S0165-5728(98)00264-1 |
0.388 |
|
| 1999 |
Davies PA, Pistis M, Hanna MC, Peters JA, Lambert JJ, Hales TG, Kirkness EF. The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature. 397: 359-63. PMID 9950429 DOI: 10.1038/16941 |
0.584 |
|
| 1998 |
Bronstein JM, Hales TG, Tyndale RF, Charles AC. A conditionally immortalized glial cell line that expresses mature myelin proteins and functional GABA(A) receptors. Journal of Neurochemistry. 70: 483-91. PMID 9453541 DOI: 10.1046/J.1471-4159.1998.70020483.X |
0.429 |
|
| 1997 |
Davies PA, Kirkness EF, Hales TG. Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells. British Journal of Pharmacology. 120: 899-909. PMID 9138697 DOI: 10.1038/Sj.Bjp.0700987 |
0.414 |
|
| 1997 |
Davies PA, Hanna MC, Hales TG, Kirkness EF. Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit. Nature. 385: 820-3. PMID 9039914 DOI: 10.1038/385820A0 |
0.476 |
|
| 1996 |
Piros ET, Hales TG, Evans CJ. Functional analysis of cloned opioid receptors in transfected cell lines Neurochemical Research. 21: 1277-1285. PMID 8947917 DOI: 10.1007/Bf02532368 |
0.391 |
|
| 1995 |
Adodra S, Hales TG. Potentiation, activation and blockade of GABAA receptors of clonal murine hypothalamic GT1-7 neurones by propofol. British Journal of Pharmacology. 115: 953-60. PMID 7582526 DOI: 10.1111/J.1476-5381.1995.Tb15903.X |
0.419 |
|
| 1994 |
Hales TG, Sanderson MJ, Charles AC. GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GT1-7) neurons. Neuroendocrinology. 59: 297-308. PMID 8159279 DOI: 10.1159/000126671 |
0.421 |
|
| 1994 |
Tyndale RF, Hales TG, Olsen RW, Tobin AJ. Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5417-28. PMID 8083745 DOI: 10.1523/Jneurosci.14-09-05417.1994 |
0.452 |
|
| 1994 |
Hales T, Tyndale R. Few cell lines with GABAA mRNAs have functional receptors The Journal of Neuroscience. 14: 5429-5436. DOI: 10.1523/Jneurosci.14-09-05429.1994 |
0.441 |
|
| 1992 |
Hales TG, Lambert JJ. Modulation of GABAA and glycine receptors by chlormethiazole. European Journal of Pharmacology. 210: 239-46. PMID 1319334 DOI: 10.1016/0014-2999(92)90410-6 |
0.468 |
|
| 1992 |
Hales TG, Jones MV, Harrison NL. EVIDENCE FOR SUBUNIT DEPENDENT DIRECT ACTIVATION OF THE GABAA RECEPTOR BY ISOFLURANE Anesthesiology. 77: A698. DOI: 10.1097/00000542-199209001-00698 |
0.483 |
|
| 1992 |
Hales TG. DIRECT ACTIVATION OF GABAA RECEPTORS BY PROPOFOL MAY BE SUBUNIT SPECIFIC Anesthesiology. 77: A695. DOI: 10.1097/00000542-199209001-00695 |
0.381 |
|
| 1991 |
Hales TG, Lambert JJ. The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. British Journal of Pharmacology. 104: 619-28. PMID 1665745 DOI: 10.1111/J.1476-5381.1991.Tb12479.X |
0.442 |
|
| 1991 |
Hales TG, Lambert JJ. MODULATION OF THE GABAA RECEPTOR BY PROPOFOL Anesthesiology. 75: A587. DOI: 10.1097/00000542-199109001-00586 |
0.375 |
|
| 1990 |
Lambert JJ, Peters JA, Sturgess NC, Hales TG. Steroid modulation of the GABAA receptor complex: electrophysiological studies. Ciba Foundation Symposium. 153: 56-71; discussion 71. PMID 1963400 DOI: 10.1002/9780470513989.ch4 |
0.415 |
|
| 1989 |
Lambert JJ, Peters JA, Hales TG, Dempster J. The properties of 5-HT3 receptors in clonal cell lines studied by patch-clamp techniques. British Journal of Pharmacology. 97: 27-40. PMID 2720311 DOI: 10.1111/J.1476-5381.1989.Tb11920.X |
0.464 |
|
| 1988 |
Peters JA, Hales TG, Lambert JJ. Divalent cations modulate 5-HT3 receptor-induced currents in N1E-115 neuroblastoma cells. European Journal of Pharmacology. 151: 491-5. PMID 2463926 DOI: 10.1016/0014-2999(88)90550-X |
0.493 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2017 |
Bull FA, Baptista-Hon DT, Sneddon C, Wright L, Walwyn W, Hales TG. Src Kinase Inhibition Attenuates Morphine Tolerance without Affecting Reinforcement or Psychomotor Stimulation. Anesthesiology. PMID 28820778 DOI: 10.1097/Aln.0000000000001834 |
0.297 |
|
| 2017 |
Bull FA, Baptista-Hon DT, Lambert JJ, Walwyn W, Hales TG. Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src. Scientific Reports. 7: 9969. PMID 28855588 DOI: 10.1038/S41598-017-10360-8 |
0.293 |
|
| 2019 |
Colvin LA, Bull F, Hales TG. Perioperative opioid analgesia-when is enough too much? A review of opioid-induced tolerance and hyperalgesia. Lancet (London, England). 393: 1558-1568. PMID 30983591 DOI: 10.1016/S0140-6736(19)30430-1 |
0.292 |
|
| 1999 |
Charles AC, Piros ET, Evans CJ, Hales TG. L-type Ca2+ channels and K+ channels specifically modulate the frequency and amplitude of spontaneous Ca2+ oscillations and have distinct roles in prolactin release in GH3 cells. The Journal of Biological Chemistry. 274: 7508-15. PMID 10066818 DOI: 10.1074/Jbc.274.11.7508 |
0.279 |
|
| 1994 |
Tyndale R, Hales T, Olsen R, Tobin A. Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines The Journal of Neuroscience. 14: 5417-5428. DOI: 10.1523/JNEUROSCI.14-09-05417.1994 |
0.274 |
|
| 1995 |
Charles AC, Hales TG. Mechanisms of spontaneous calcium oscillations and action potentials in immortalized hypothalamic (GT1-7) neurons. Journal of Neurophysiology. 73: 56-64. PMID 7714589 DOI: 10.1152/Jn.1995.73.1.56 |
0.256 |
|
| 2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, ... ... Hales TG, et al. The Concise Guide to PHARMACOLOGY 2013/14: overview. British Journal of Pharmacology. 170: 1449-58. PMID 24528237 DOI: 10.1111/Bph.12444 |
0.248 |
|
| 2017 |
Wright L, Baptista-Hon D, Bull F, Dalgaty F, Gallacher M, Ibbotson SH, Hales TG. Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. Pain. PMID 29194091 DOI: 10.1097/J.Pain.0000000000001096 |
0.24 |
|
| 2018 |
Torrance N, Mansoor R, Wang H, Gilbert S, Macfarlane GJ, Serpell M, Baldacchino A, Hales TG, Donnan P, Wyper G, Smith BH, Colvin L. Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study. British Journal of Anaesthesia. 120: 1345-1355. PMID 29793600 DOI: 10.1016/J.Bja.2018.02.022 |
0.224 |
|
| 2021 |
Singleton S, Baptista-Hon DT, Edelsten E, McCaughey KS, Camplisson E, Hales TG. TRV130 partial agonism and capacity to induce anti-nociceptive tolerance revealed through reducing available μ-opioid receptor number. British Journal of Pharmacology. PMID 33555037 DOI: 10.1111/bph.15409 |
0.223 |
|
| 1998 |
Carlisle HJ, Hales TG, Schlinger BA. Characterization of neuronal zebra finch GABA(A) receptors: Steroid effects Journal of Comparative Physiology - a Sensory, Neural, and Behavioral Physiology. 182: 531-538. DOI: 10.1007/S003590050200 |
0.22 |
|
| 2019 |
Forget P, Aguirre JA, Bencic I, Borgeat A, Cama A, Condron C, Eintrei C, Eroles P, Gupta A, Hales TG, Ionescu D, Johnson M, Kabata P, Kirac I, Ma D, et al. How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence. Cancers. 11. PMID 31035321 DOI: 10.3390/Cancers11050592 |
0.216 |
|
| 2015 |
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K, Hales TG, Hemmings HC, Hollmann MW, Kurz A, Ma D, et al. Consensus statement from the BJA Workshop on Cancer and Anaesthesia. British Journal of Anaesthesia. 114: 2-3. PMID 25104229 DOI: 10.1093/Bja/Aeu262 |
0.209 |
|
| 2011 |
Hales TG. Arresting the development of morphine tolerance and dependence. British Journal of Anaesthesia. 107: 653-5. PMID 21997147 DOI: 10.1093/Bja/Aer294 |
0.204 |
|
| 2020 |
Meng W, Chan BW, Harris C, Freidin MB, Hebert HL, Adams MJ, Campbell A, Hayward C, Zheng H, Zhang X, Colvin LA, Hales TG, Palmer CNA, Williams FMK, McIntosh A, et al. A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank. Human Molecular Genetics. PMID 32246137 DOI: 10.1093/Hmg/Ddaa058 |
0.195 |
|
| 2023 |
Kuo CS, Dobi S, Gök C, Da Silva Costa A, Main A, Robertson-Gray O, Baptista-Hon D, Wypijewski KJ, Costello H, Hales TG, MacQuaide N, Smith GL, Fuller W. Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207887120. PMID 36745790 DOI: 10.1073/pnas.2207887120 |
0.174 |
|
| 2021 |
Lopez-Charcas O, Pukkanasut P, Velu SE, Brackenbury WJ, Hales TG, Besson P, Gomora JC, Roger S. Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers. Iscience. 24: 102270. PMID 33817575 DOI: 10.1016/j.isci.2021.102270 |
0.173 |
|
| 2011 |
Hales TG. Mechanisms of anaesthetics: lessons learned from creatures great and small. Anaesthesia. 66: 334-7. PMID 21453384 DOI: 10.1111/J.1365-2044.2011.06723.X |
0.17 |
|
| 2009 |
O'Brien TJ, Goodsaid F, Plack M, Harralson A, Harrouk W, Hales TG, Mandel HG, Perry DC, Kennedy K, Sarvazyan N, Chiappinelli VA. Development of an undergraduate pharmacogenomics curriculum. Pharmacogenomics. 10: 1979-86. PMID 19958096 DOI: 10.2217/Pgs.09.145 |
0.169 |
|
| 2023 |
Singleton S, Sneddon C, Bakina A, Lambert JJ, Hales TG. Early-life adversity increases morphine tolerance and persistent inflammatory hypersensitivity through upregulation of δ opioid receptors in mice. Pain. PMID 37171192 DOI: 10.1097/j.pain.0000000000002925 |
0.166 |
|
| 2016 |
Cui J, Zhao H, Ma D, Ciechanowicz S, Lee M, Kciuk O, Koelewyn A, Beale N, Russell R, Buck L, Fido D, Quinlan J, Warnaby C, Pocknall C, Milan Z, ... ... Hales T, et al. Abstracts from the BJA Research Forum York, November 12–13, 2015 Bja: British Journal of Anaesthesia. 116. DOI: 10.1093/Bja/Aev406 |
0.158 |
|
| 2023 |
Singleton S, Hales TG. Morphine-induced mechanical hypersensitivity in mice requires δ receptors, β-arrestin2 and c-Src activity. The Journal of Physiology. PMID 36859810 DOI: 10.1113/JP284003 |
0.155 |
|
| 2023 |
Abboussi O, Khan ZA, Ibork H, Zulu SS, Daniels W, Taghzouti K, Hales TG. CB2 agonist mitigates cocaine-induced reinstatement of place preference and modulates the inflammatory response in mice. Behavioural Pharmacology. PMID 38085651 DOI: 10.1097/FBP.0000000000000759 |
0.143 |
|
| 2022 |
McLeod GA, Sadler A, Hales TG. Traumatic needle damage to nerves during regional anesthesia: presentation of a novel mechanotransduction hypothesis. Regional Anesthesia and Pain Medicine. PMID 35878962 DOI: 10.1136/rapm-2022-103583 |
0.085 |
|
| 2021 |
Sharma S, Higgins C, Cameron P, Bimali I, Hales TG, Bennett MI, Colvin L, Smith BH. Validation of the Nepali version of the self-reported Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) in adults with chronic pain and predominantly low-literacy levels. The Journal of Pain. PMID 34583020 DOI: 10.1016/j.jpain.2021.09.004 |
0.037 |
|
| 2023 |
John S, Walwyn DR, DeFea K, Hales TG, Walwyn W. Editorial: Opioids in the time of the COVID-19 pandemic: from cellular mechanisms to public health policy. Frontiers in Pharmacology. 14: 1251958. PMID 37521481 DOI: 10.3389/fphar.2023.1251958 |
0.03 |
|
| 2023 |
Higgins C, Sharma S, Bimali I, Hales TG, Cameron PA, Smith BH, Colvin LA. Cross-sectional study examining the epidemiology of chronic pain in Nepal. Pain Reports. 8: e1067. PMID 36818647 DOI: 10.1097/PR9.0000000000001067 |
0.025 |
|
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