Neil L. Harrison - Publications

Affiliations: 
Columbia University, New York, NY 
 University of California, San Francisco, San Francisco, CA 
 University of Chicago, Chicago, IL 
 Weill Cornell Medical College, New York, NY, United States 
Area:
GABA-A receptors

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li M, Cabrera-Garcia D, Salling MC, Au E, Yang G, Harrison NL. Alcohol reduces the activity of somatostatin interneurons in the mouse prefrontal cortex: a neural basis for its disinhibitory effect? Neuropharmacology. 108501. PMID 33636191 DOI: 10.1016/j.neuropharm.2021.108501  0.732
2020 Salling MC, Harrison NL. Constitutive Genetic Deletion of Increases Alcohol Preference during Adolescence. Brain Sciences. 10. PMID 33105624 DOI: 10.3390/brainsci10110763  0.729
2018 Salling MC, Jane Skelly M, Avegno E, Regan S, Zeric T, Nichols E, Harrison NL. Alcohol consumption during adolescence in a mouse model of binge drinking alters the intrinsic excitability and function of the prefrontal cortex through a reduction in the hyperpolarization-activated cation current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29915134 DOI: 10.1523/Jneurosci.0550-18.2018  0.738
2017 McCracken LM, Lowes DC, Salling MC, Carreau-Vollmer C, Odean NN, Blednov YA, Betz H, Harris RA, Harrison NL. Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784756 DOI: 10.1073/Pnas.1703839114  0.766
2017 Harrison NL, Skelly MJ, Grosserode EP, Lowes DC, Zeric T, Phister S, Salling MC. Effects of acute alcohol on excitability in the CNS. Neuropharmacology. PMID 28479395 DOI: 10.1016/J.Neuropharm.2017.04.007  0.746
2017 Yocum GT, Turner DL, Danielsson J, Barajas MB, Zhang Y, Xu D, Harrison N, Homanics GE, Farber DL, Emala CW. GABAA Receptor α4 Subunit Knockout Enhances Lung Inflammation and Airway Reactivity in a Murine Asthma Model. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00107.2017. PMID 28473323 DOI: 10.1152/Ajplung.00107.2017  0.345
2016 Avegno EM, Salling MC, Borgkvist A, Mrejeru A, Whitebirch AC, Margolis EB, Sulzer D, Harrison NL. Voluntary adolescent drinking enhances excitation by low levels of alcohol in a subset of dopaminergic neurons in the ventral tegmental area. Neuropharmacology. PMID 27475082 DOI: 10.1016/J.Neuropharm.2016.07.031  0.745
2016 Canetta S, Bolkan S, Padilla-Coreano N, Song LJ, Sahn R, Harrison NL, Gordon JA, Brown A, Kellendonk C. Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons. Molecular Psychiatry. PMID 26830140 DOI: 10.1038/Mp.2015.222  0.322
2015 Dixon CL, Harrison NL, Lynch JW, Keramidas A. Zolpidem and eszopiclone prime α1β2γ2 GABAA receptors for longer duration of activity. British Journal of Pharmacology. 172: 3522-36. PMID 25817320 DOI: 10.1111/Bph.13142  0.413
2015 Mrejeru A, Martí-Prats L, Avegno EM, Harrison NL, Sulzer D. A subset of ventral tegmental area dopamine neurons responds to acute ethanol. Neuroscience. 290: 649-58. PMID 25660505 DOI: 10.1016/J.Neuroscience.2014.12.081  0.345
2015 Gallos G, Yocum GT, Siviski ME, Yim PD, Fu XW, Poe MM, Cook JM, Harrison N, Perez-Zoghbi J, Emala CW. Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L931-42. PMID 25659897 DOI: 10.1152/Ajplung.00107.2014  0.392
2015 Gallo EF, Salling MC, Feng B, Morón JA, Harrison NL, Javitch JA, Kellendonk C. Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1609-18. PMID 25578797 DOI: 10.1038/Npp.2015.11  0.739
2015 Salling MC, Avegno EA, Santoro B, Siegelbaum SA, Harrison NL. P-60EXCESSIVE ALCOHOL CONSUMPTION DURING ADOLESCENCE IN MICE LEADS TO PERSISTENT ALTERATIONS IN PREFRONTAL CORTEX EXCITABILITY AND FUNCTION Alcohol and Alcoholism. 50: i60.3-i60. DOI: 10.1093/Alcalc/Agv080.60  0.725
2015 Avegno EM, Mrejeru A, Salling M, Sulzer D, Harrison NL. SY02-2DRINKING HISTORY ENHANCES DOPAMINE NEURONAL RESPONSE TO ETHANOL Alcohol and Alcoholism. 50: i35.2-i35. DOI: 10.1093/Alcalc/Agv076.129  0.728
2014 Salling MC, Harrison NL. Strychnine-sensitive glycine receptors on pyramidal neurons in layers II/III of the mouse prefrontal cortex are tonically activated. Journal of Neurophysiology. 112: 1169-78. PMID 24872538 DOI: 10.1152/Jn.00714.2013  0.805
2013 Varodayan FP, Harrison NL. HSF1 transcriptional activity mediates alcohol induction of Vamp2 expression and GABA release. Frontiers in Integrative Neuroscience. 7: 89. PMID 24376402 DOI: 10.3389/Fnint.2013.00089  0.74
2013 Pignataro L, Varodayan FP, Tannenholz LE, Protiva P, Harrison NL. Brief alcohol exposure alters transcription in astrocytes via the heat shock pathway. Brain and Behavior. 3: 114-33. PMID 23533150 DOI: 10.1002/Brb3.125  0.69
2012 Cazorla M, Shegda M, Ramesh B, Harrison NL, Kellendonk C. Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2398-409. PMID 22396414 DOI: 10.1523/Jneurosci.6056-11.2012  0.38
2011 Varodayan FP, Pignataro L, Harrison NL. Alcohol induces synaptotagmin 1 expression in neurons via activation of heat shock factor 1. Neuroscience. 193: 63-71. PMID 21816209 DOI: 10.1016/J.Neuroscience.2011.07.035  0.724
2011 Blednov YA, Borghese CM, McCracken ML, Benavidez JM, Geil CR, Osterndorff-Kahanek E, Werner DF, Iyer S, Swihart A, Harrison NL, Homanics GE, Harris RA. Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. The Journal of Pharmacology and Experimental Therapeutics. 336: 145-54. PMID 20876231 DOI: 10.1124/Jpet.110.171645  0.411
2011 Werner DF, Swihart A, Rau V, Jia F, Borghese CM, McCracken ML, Iyer S, Fanselow MS, Oh I, Sonner JM, Eger EI, Harrison NL, Harris RA, Homanics GE. Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane. The Journal of Pharmacology and Experimental Therapeutics. 336: 134-44. PMID 20807777 DOI: 10.1124/Jpet.110.170431  0.522
2010 Keramidas A, Harrison NL. The activation mechanism of alpha1beta2gamma2S and alpha3beta3gamma2S GABAA receptors. The Journal of General Physiology. 135: 59-75. PMID 20038526 DOI: 10.1085/jgp.200910317  0.467
2009 Rau V, Iyer SV, Oh I, Chandra D, Harrison N, Eger EI, Fanselow MS, Homanics GE, Sonner JM. Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane. Anesthesia and Analgesia. 109: 1816-22. PMID 19923508 DOI: 10.1213/Ane.0B013E3181Bf6Ae6  0.491
2009 Belelli D, Harrison NL, Maguire J, Macdonald RL, Walker MC, Cope DW. Extrasynaptic GABAA receptors: form, pharmacology, and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12757-63. PMID 19828786 DOI: 10.1523/Jneurosci.3340-09.2009  0.53
2009 Pignataro L, Varodayan FP, Tannenholz LE, Harrison NL. The regulation of neuronal gene expression by alcohol. Pharmacology & Therapeutics. 124: 324-35. PMID 19781570 DOI: 10.1016/J.Pharmthera.2009.09.002  0.704
2009 Jia F, Goldstein PA, Harrison NL. The modulation of synaptic GABA(A) receptors in the thalamus by eszopiclone and zolpidem. The Journal of Pharmacology and Experimental Therapeutics. 328: 1000-6. PMID 19033556 DOI: 10.1124/Jpet.108.146084  0.728
2009 Werner DF, Swihart AR, Ferguson C, Lariviere WR, Harrison NL, Homanics GE. Alcohol-induced tolerance and physical dependence in mice with ethanol insensitive alpha1 GABA A receptors. Alcoholism, Clinical and Experimental Research. 33: 289-99. PMID 19032579 DOI: 10.1111/J.1530-0277.2008.00832.X  0.404
2009 Ying SW, Werner DF, Homanics GE, Harrison NL, Goldstein PA. Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms. Neuropharmacology. 56: 438-47. PMID 18948126 DOI: 10.1016/J.Neuropharm.2008.09.015  0.747
2009 Keramidas A, Harrison N. Functional Characteristics of alpha3beta3gamma2 and alpha1beta2gamma2 GABA-A receptors Biophysical Journal. 96: 487a. DOI: 10.1016/J.BPJ.2008.12.2513  0.453
2008 Jia F, Chandra D, Homanics GE, Harrison NL. Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus. The Journal of Pharmacology and Experimental Therapeutics. 326: 475-82. PMID 18477766 DOI: 10.1124/Jpet.108.139303  0.461
2008 Keramidas A, Harrison NL. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of General Physiology. 131: 163-81. PMID 18227274 DOI: 10.1085/jgp.200709871  0.449
2008 Trudell JR, Yue ME, Bertaccini EJ, Jenkins A, Harrison NL. Molecular modeling and mutagenesis reveals a tetradentate binding site for Zn2+ in GABA(A) alphabeta receptors and provides a structural basis for the modulating effect of the gamma subunit. Journal of Chemical Information and Modeling. 48: 344-9. PMID 18197653 DOI: 10.1021/ci700324a  0.628
2008 Jia F, Yue M, Chandra D, Keramidas A, Goldstein PA, Homanics GE, Harrison NL. Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 106-15. PMID 18171928 DOI: 10.1523/Jneurosci.3996-07.2008  0.746
2008 Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL. Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus. The Journal of Pharmacology and Experimental Therapeutics. 324: 1127-35. PMID 18094320 DOI: 10.1124/Jpet.107.134569  0.758
2008 Chandra D, Werner DF, Liang J, Suryanarayanan A, Harrison NL, Spigelman I, Olsen RW, Homanics GE. Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice. Alcoholism, Clinical and Experimental Research. 32: 10-8. PMID 18076749 DOI: 10.1111/J.1530-0277.2007.00563.X  0.44
2008 Trudell JR, Yue ME, Bertaccini EJ, Jenkins A, Harrison NL. ChemInform Abstract: Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn2+in GABAAαβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit. Cheminform. 39. DOI: 10.1002/CHIN.200821214  0.49
2007 Pignataro L, Miller AN, Ma L, Midha S, Protiva P, Herrera DG, Harrison NL. Alcohol regulates gene expression in neurons via activation of heat shock factor 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12957-66. PMID 18032669 DOI: 10.1523/Jneurosci.4142-07.2007  0.32
2007 Harrison NL. Mechanisms of sleep induction by GABA(A) receptor agonists. The Journal of Clinical Psychiatry. 68: 6-12. PMID 17539703  0.469
2007 Jia F, Pignataro L, Harrison NL. GABAA receptors in the thalamus: alpha4 subunit expression and alcohol sensitivity. Alcohol (Fayetteville, N.Y.). 41: 177-85. PMID 17521848 DOI: 10.1016/j.alcohol.2007.03.010  0.446
2007 Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI, Homanics GE. Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane. Anesthesiology. 106: 107-13. PMID 17197852 DOI: 10.1097/00000542-200701000-00019  0.413
2006 Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE. GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol. Proceedings of the National Academy of Sciences of the United States of America. 103: 15230-5. PMID 17005728 DOI: 10.1073/Pnas.0604304103  0.479
2006 Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL. An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 208-18. PMID 16807363 DOI: 10.1124/Jpet.106.104406  0.549
2006 Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319: 219-27. PMID 16785315 DOI: 10.1124/Jpet.106.106161  0.431
2006 Keramidas A, Kash TL, Harrison NL. The pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor. The Journal of Physiology. 575: 11-22. PMID 16763005 DOI: 10.1113/jphysiol.2005.102756  0.705
2006 Elsen FP, Liljelund P, Werner DF, Olsen RW, Homanics GE, Harrison NL. GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice. Brain Research. 1078: 60-70. PMID 16490182 DOI: 10.1016/J.Brainres.2006.01.036  0.468
2006 Ying SW, Abbas SY, Harrison NL, Goldstein PA. Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons. The European Journal of Neuroscience. 23: 465-80. PMID 16420453 DOI: 10.1111/J.1460-9568.2005.04587.X  0.68
2005 Jia F, Pignataro L, Schofield CM, Yue M, Harrison NL, Goldstein PA. An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons. Journal of Neurophysiology. 94: 4491-501. PMID 16162835 DOI: 10.1152/Jn.00421.2005  0.828
2005 Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL. Emerging molecular mechanisms of general anesthetic action. Trends in Pharmacological Sciences. 26: 503-10. PMID 16126282 DOI: 10.1016/J.Tips.2005.08.006  0.696
2005 Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA. Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol. The Journal of Pharmacology and Experimental Therapeutics. 315: 517-25. PMID 16033909 DOI: 10.1124/Jpet.105.091801  0.651
2005 Sonner JM, Vissel B, Royle G, Maurer A, Gong D, Baron NV, Harrison N, Fanselow M, Eger EI. The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene. Anesthesia and Analgesia. 101: 143-8, table of cont. PMID 15976221 DOI: 10.1213/01.Ane.0000152615.53435.B4  0.422
2005 Hall AC, Stevens RJ, Betts BA, Yeung WY, Kelley JC, Harrison NL. Subunit-dependent block by isoflurane of wild-type and mutant alpha(1)S270H GABA(A) receptor currents in Xenopus oocytes. Neuroscience Letters. 382: 332-7. PMID 15925114 DOI: 10.1016/j.neulet.2005.03.029  0.528
2005 Schofield CM, Harrison NL. Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit. Brain Research. 1032: 30-5. PMID 15680938 DOI: 10.1016/J.Brainres.2004.11.002  0.817
2005 Homanics GE, Elsen FP, Ying SW, Jenkins A, Ferguson C, Sloat B, Yuditskaya S, Goldstein PA, Kralic JE, Morrow AL, Harrison NL. A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse. Genes, Brain, and Behavior. 4: 10-9. PMID 15660664 DOI: 10.1111/J.1601-183X.2004.00090.X  0.782
2005 Jenkins A, Kash TL, Schofield CM, Trudell JR, Harrison NL. Structural elements governing activation and modulation of GABAA receptors International Congress Series. 1283: 26-31. DOI: 10.1016/j.ics.2005.07.075  0.784
2004 Kash TL, Kim T, Trudell JR, Harrison NL. Evaluation of a proposed mechanism of ligand-gated ion channel activation in the GABAA and glycine receptors. Neuroscience Letters. 371: 230-4. PMID 15519763 DOI: 10.1016/j.neulet.2004.09.002  0.734
2004 Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 12543-8. PMID 15310843 DOI: 10.1073/Pnas.0404700101  0.3
2004 Schofield CM, Trudell JR, Harrison NL. Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation. Biochemistry. 43: 10058-63. PMID 15287733 DOI: 10.1021/Bi036159G  0.798
2004 Ma L, Song L, Radoi GE, Harrison NL. Transcriptional regulation of the mouse gene encoding the alpha-4 subunit of the GABAA receptor. The Journal of Biological Chemistry. 279: 40451-61. PMID 15265862 DOI: 10.1074/jbc.M406827200  0.449
2004 Kash TL, Trudell JR, Harrison NL. Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor. Biochemical Society Transactions. 32: 540-6. PMID 15157180 DOI: 10.1042/BST0320540  0.656
2004 Hall AC, Rowan KC, Stevens RJ, Kelley JC, Harrison NL. The effects of isoflurane on desensitized wild-type and alpha 1(S270H) gamma-aminobutyric acid type A receptors. Anesthesia and Analgesia. 98: 1297-304, table of c. PMID 15105205 DOI: 10.1213/01.ANE.0000111108.78745.AD  0.54
2004 Castaldo P, Stefanoni P, Miceli F, Coppola G, Del Giudice EM, Bellini G, Pascotto A, Trudell JR, Harrison NL, Annunziato L, Taglialatela M. A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists. The Journal of Biological Chemistry. 279: 25598-604. PMID 15066993 DOI: 10.1074/jbc.M311021200  0.464
2004 Kash TL, Dizon MJ, Trudell JR, Harrison NL. Charged residues in the beta2 subunit involved in GABAA receptor activation. The Journal of Biological Chemistry. 279: 4887-93. PMID 14610076 DOI: 10.1074/jbc.M311441200  0.68
2003 Barberi T, Klivenyi P, Calingasan NY, Lee H, Kawamata H, Loonam K, Perrier AL, Bruses J, Rubio ME, Topf N, Tabar V, Harrison NL, Beal MF, Moore MA, Studer L. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nature Biotechnology. 21: 1200-7. PMID 14502203 DOI: 10.1038/Nbt870  0.334
2003 Nishikawa K, Harrison NL. The actions of sevoflurane and desflurane on the gamma-aminobutyric acid receptor type A: effects of TM2 mutations in the alpha and beta subunits. Anesthesiology. 99: 678-84. PMID 12960553 DOI: 10.1097/00000542-200309000-00024  0.466
2003 Schofield CM, Jenkins A, Harrison NL. A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor. The Journal of Biological Chemistry. 278: 34079-83. PMID 12826676 DOI: 10.1074/Jbc.M302416200  0.808
2003 Ruscito BJ, Harrison NL. Hemoglobin metabolites mimic benzodiazepines and are possible mediators of hepatic encephalopathy. Blood. 102: 1525-8. PMID 12714506 DOI: 10.1182/Blood-2003-03-0739  0.761
2003 Topf N, Jenkins A, Baron N, Harrison NL. Effects of isoflurane on gamma-aminobutyric acid type A receptors activated by full and partial agonists. Anesthesiology. 98: 306-11. PMID 12552186 DOI: 10.1097/00000542-200302000-00007  0.671
2003 Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL. Coupling of agonist binding to channel gating in the GABA(A) receptor. Nature. 421: 272-5. PMID 12529644 DOI: 10.1038/nature01280  0.743
2003 Kash TL, Jenkins A, Harrison NL. Molecular volume determines the activity of the halogenated alkane bromoform at wild-type and mutant GABA(A) receptors. Brain Research. 960: 36-41. PMID 12505655 DOI: 10.1016/S0006-8993(02)03748-4  0.779
2002 Goldstein PA, Elsen FP, Ying SW, Ferguson C, Homanics GE, Harrison NL. Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit. Journal of Neurophysiology. 88: 3208-17. PMID 12466441 DOI: 10.1152/Jn.00885.2001  0.724
2002 Jenkins A, Andreasen A, Trudell JR, Harrison NL. Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure. Neuropharmacology. 43: 669-78. PMID 12367612 DOI: 10.1016/S0028-3908(02)00175-2  0.667
2002 Krasowski MD, Hong X, Hopfinger AJ, Harrison NL. 4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor. Journal of Medicinal Chemistry. 45: 3210-21. PMID 12109905 DOI: 10.1021/jm010461a  0.418
2002 Nishikawa K, Jenkins A, Paraskevakis I, Harrison NL. Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations. Neuropharmacology. 42: 337-45. PMID 11897112 DOI: 10.1016/S0028-3908(01)00189-7  0.657
2002 Bertaccini EJ, Trudell JR, Jenkins A, Harrison NL. Docking of Anesthetics to a GABA Receptor Model Reproduces In Vitro Potency Order Anesthesiology. 96: A116. DOI: 10.1097/00000542-200209002-00116  0.624
2001 Krasowski MD, Nishikawa K, Nikolaeva N, Lin A, Harrison NL. Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics. Neuropharmacology. 41: 952-64. PMID 11747900 DOI: 10.1016/S0028-3908(01)00141-1  0.514
2001 Kung AY, Rick C, O'Shea S, Harrison NL, McGehee DS. Expression of glycine receptors in rat sensory neurons vs. HEK293 cells yields different functional properties. Neuroscience Letters. 309: 202-6. PMID 11514076 DOI: 10.1016/S0304-3940(01)02066-3  0.795
2001 Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC. Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia. Anesthesiology. 94: 1050-7. PMID 11465597 DOI: 10.1097/00000542-200106000-00020  0.596
2001 Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors. Neuroscience Letters. 305: 77-80. PMID 11356312 DOI: 10.1016/S0304-3940(01)01646-9  0.532
2001 Krasowski MD, Jenkins A, Flood P, Kung AY, Hopfinger AJ, Harrison NL. General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility. The Journal of Pharmacology and Experimental Therapeutics. 297: 338-51. PMID 11259561  0.612
2001 Jenkins A, Greenblatt EP, Faulkner HJ, Bertaccini E, Light A, Lin A, Andreasen A, Viner A, Trudell JR, Harrison NL. Evidence for a common binding cavity for three general anesthetics within the GABAA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC136. PMID 11245705 DOI: 10.1523/Jneurosci.21-06-J0002.2001  0.583
2001 Krasowski MD, Harris RA, Harrison NL. Allosteric Modulation of GABAA Receptor Function by General Anesthetics and Alcohols Handbook of Experimental Pharmacology. 150: 141-172. DOI: 10.1007/978-3-642-56833-6_5  0.416
2000 Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected]. Neuroscience Letters. 293: 155-8. PMID 11036184 DOI: 10.1016/S0304-3940(00)01503-2  0.543
2000 Ueno S, Lin A, Nikolaeva N, Trudell JR, Mihic SJ, Harris RA, Harrison NL. Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. British Journal of Pharmacology. 131: 296-302. PMID 10991923 DOI: 10.1038/Sj.Bjp.0703504  0.513
2000 O'Shea SM, Harrison NL. Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor alpha 2 subunit define agonist efficacy and potency. The Journal of Biological Chemistry. 275: 22764-8. PMID 10801806 DOI: 10.1074/jbc.M001299200  0.82
2000 Krasowski MD, Harrison NL. The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations. British Journal of Pharmacology. 129: 731-43. PMID 10683198 DOI: 10.1038/sj.bjp.0703087  0.511
2000 O'Shea SM, Wong LC, Harrison NL. Propofol increases agonist efficacy at the GABA(A) receptor. Brain Research. 852: 344-8. PMID 10678761 DOI: 10.1016/S0006-8993(99)02151-4  0.824
2000 Jenkins A, Harrison N. Room 224-226, 10/18/2000 10: 30 AM - 12: 00 PM (PD) Halothane Action at the GABAA Receptor is Determined by Side Chain Volume at α270  Anesthesiology. 93: A-809. DOI: 10.1097/00000542-200009001-00809  0.482
2000 Harrison N, Andreasen A, Viner A, Light A, Jenkins A. Room D, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Multiple Mutations Are Required to Remove Chloroform Sensitivity from GABAAReceptors  Anesthesiology. 93: A-754. DOI: 10.1097/00000542-200009001-00754  0.429
1999 Koltchine VV, Finn SE, Jenkins A, Nikolaeva N, Lin A, Harrison NL. Agonist gating and isoflurane potentiation in the human gamma-aminobutyric acid type A receptor determined by the volume of a second transmembrane domain residue. Molecular Pharmacology. 56: 1087-93. PMID 10531417 DOI: 10.1124/Mol.56.5.1087  0.649
1999 Krasowski MD, Harrison NL. General anaesthetic actions on ligand-gated ion channels. Cellular and Molecular Life Sciences : Cmls. 55: 1278-303. PMID 10487207 DOI: 10.1007/s000180050371  0.308
1999 Ueno S, Wick MJ, Ye Q, Harrison NL, Harris RA. Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes. British Journal of Pharmacology. 127: 377-82. PMID 10385236 DOI: 10.1038/Sj.Bjp.0702563  0.485
1999 Homanics GE, Harrison NL, Quinlan JJ, Krasowski MD, Rick CE, de Blas AL, Mehta AK, Kist F, Mihalek RM, Aul JJ, Firestone LL. Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor. Neuropharmacology. 38: 253-65. PMID 10218866 DOI: 10.1016/S0028-3908(98)00177-4  0.479
1998 Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA. Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proceedings of the National Academy of Sciences of the United States of America. 95: 6504-9. PMID 9600996 DOI: 10.1073/Pnas.95.11.6504  0.413
1998 Rick CE, Ye Q, Finn SE, Harrison NL. Neurosteroids act on the GABA(A) receptor at sites on the N-terminal side of the middle of TM2. Neuroreport. 9: 379-83. PMID 9512375 DOI: 10.1097/00001756-199802160-00004  0.525
1998 Krasowski MD, Finn SE, Ye Q, Harrison NL. Trichloroethanol modulation of recombinant GABAA, glycine and GABA rho 1 receptors. The Journal of Pharmacology and Experimental Therapeutics. 284: 934-42. PMID 9495852  0.45
1998 Krasowski MD, Koltchine VV, Rick CE, Ye Q, Finn SE, Harrison NL. Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane. Molecular Pharmacology. 53: 530-8. PMID 9495821 DOI: 10.1124/Mol.53.3.530  0.534
1998 Krasowski MD, Rick CE, Harrison NL, Firestone LL, Homanics GE. A deficit of functional GABA(A) receptors in neurons of beta 3 subunit knockout mice. Neuroscience Letters. 240: 81-4. PMID 9486477 DOI: 10.1016/S0304-3940(97)00929-4  0.427
1998 Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. The Journal of Biological Chemistry. 273: 3314-9. PMID 9452448 DOI: 10.1074/Jbc.273.6.3314  0.351
1998 Koltchine VV, Nikoleava N, Harrison NL, Krasowski MD. SEVOFLURANE AND ISOFLURANE SHARE A COMMON SITE ON THE GABA-A RECEPTOR Anesthesiology. 89: 697A. DOI: 10.1097/00000542-199809130-00003  0.491
1998 Harrison N, Mihic S, Ye Q, Wick M, Krasowski &, Finn S, Harris R. SITES FOR ISOFLURANE ACTION ON INHIBITORY AMINO ACID RECEPTORS REVEALED BY MUTAGENESIS? Anesthesia & Analgesia. 86: 456S. DOI: 10.1097/00000539-199802001-00454  0.397
1997 Lavoie AM, Tingey JJ, Harrison NL, Pritchett DB, Twyman RE. Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform. Biophysical Journal. 73: 2518-26. PMID 9370445 DOI: 10.1016/S0006-3495(97)78280-8  0.517
1997 Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389: 385-9. PMID 9311780 DOI: 10.1038/38738  0.553
1997 Krasowski MD, O'Shea SM, Rick CE, Whiting PJ, Hadingham KL, Czajkowski C, Harrison NL. Alpha subunit isoform influences GABA(A) receptor modulation by propofol. Neuropharmacology. 36: 941-9. PMID 9257938 DOI: 10.1016/S0028-3908(97)00074-9  0.836
1997 Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proceedings of the National Academy of Sciences of the United States of America. 94: 4143-8. PMID 9108119 DOI: 10.1073/Pnas.94.8.4143  0.384
1997 Harrison N, Mihic &, Ye Q, Koltchine V, Finn S, Krasowski M, Wick M, Harris R. A703 CRITICAL AMINO ACID RESIDUES FOR THE ALLOSTERIC ACTIONS OF ISOFLURANE AND ENFLURANE IN THE HUMAN GABA sub A RECEPTOR Anesthesiology. 87: 703A. DOI: 10.1097/00000542-199709001-00703  0.436
1997 Harrison N, Mihic &, Ye Q, Finn S, Wick M, Koltchine V, Mascia M, Harris R. A616 MOLECULAR SITES OF ACTION OF n-ALKANOLS IN THE HUMAN GLYCINE RECEPTOR? Anesthesiology. 87: 616A. DOI: 10.1097/00000542-199709001-00616  0.318
1997 Harrison N, Mihic &, Wick M, Finn S, Ye Q, Harris R. A615 MOLECULAR SITES OF ACTION OF n-ALKANOLS IN THE HUMAN GABA sub A RECEPTOR? Anesthesiology. 87: 615A. DOI: 10.1097/00000542-199709001-00615  0.417
1997 Krasowski &, Finn S, Koltchine V, Ye Q, Harrison N. A614 DISTINCT MOLECULAR SITES OF ACTION OF ISOFLURANE AND PROPOFOL IN THE HUMAN GABA sub A RECEPTOR Anesthesiology. 87: 614A. DOI: 10.1097/00000542-199709001-00614  0.435
1997 Krasowski &, Finn S, Koltchine V, Ye Q, Harrison N. A613 ETOMIDATE AND ISOFLURANE EXERT THEIR ACTIONS ON THE HUMAN GABA sub A RECEPTOR AT DIFFERENT SITES Anesthesiology. 87: 613A. DOI: 10.1097/00000542-199709001-00613  0.437
1996 Koltchine VV, Ye Q, Finn SE, Harrison NL. Chimeric GABAA/glycine receptors: expression and barbiturate pharmacology. Neuropharmacology. 35: 1445-56. PMID 9014160 DOI: 10.1016/S0028-3908(96)00088-3  0.448
1995 Jones MV, Harrison NL, Pritchett DB, Hales TG. Modulation of the GABAA receptor by propofol is independent of the gamma subunit. The Journal of Pharmacology and Experimental Therapeutics. 274: 962-8. PMID 7636760  0.456
1994 Zimmerman SA, Jones MV, Harrison NL. Potentiation of gamma-aminobutyric acidA receptor Cl- current correlates with in vivo anesthetic potency. The Journal of Pharmacology and Experimental Therapeutics. 270: 987-91. PMID 7932211  0.426
1994 Bloomenthal AB, Goldwater E, Pritchett DB, Harrison NL. Biphasic modulation of the strychnine-sensitive glycine receptor by Zn2+. Molecular Pharmacology. 46: 1156-9. PMID 7808436  0.364
1994 Bloomenthal AB, Goldwater E, Kugler JL, Jones MV, Hara M, Levitin M, Carter D, Pritchett DB, Harrison NL. General Anesthetic Modulation of Amino Acid Transmitter Receptors Anesthesiology. 81: A1486. DOI: 10.1097/00000542-199409001-01485  0.376
1993 Lovinger DM, Zimmerman SA, Levitin M, Jones MV, Harrison NL. Trichloroethanol potentiates synaptic transmission mediated by gamma-aminobutyric acidA receptors in hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 264: 1097-103. PMID 8383736  0.44
1993 Harrison NL, Kugler JL, Jones MV, Greenblatt EP, Pritchett DB. Positive modulation of human gamma-aminobutyric acid type A and glycine receptors by the inhalation anesthetic isoflurane. Molecular Pharmacology. 44: 628-32. PMID 7690453  0.417
1993 Jones MV, Harrison NL. Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons. Journal of Neurophysiology. 70: 1339-49. PMID 7506753 DOI: 10.1152/Jn.1993.70.4.1339  0.465
1992 Bleakman D, Harrison NL, Colmers WF, Miller RJ. Investigations into neuropeptide Y-mediated presynaptic inhibition in cultured hippocampal neurones of the rat. British Journal of Pharmacology. 107: 334-40. PMID 1358389 DOI: 10.1111/J.1476-5381.1992.Tb12747.X  0.368
1992 Lambert NA, Levitin M, Harrison NL. Induction of giant depolarizing potentials by zinc in area CA1 of the rat hippocampus does not result from block of GABAB receptors. Neuroscience Letters. 135: 215-8. PMID 1352630 DOI: 10.1016/0304-3940(92)90439-E  0.45
1992 Jones MV, Brooks PA, Harrison NL. Enhancement of gamma-aminobutyric acid-activated Cl- currents in cultured rat hippocampal neurones by three volatile anaesthetics. The Journal of Physiology. 449: 279-93. PMID 1326046 DOI: 10.1113/Jphysiol.1992.Sp019086  0.518
1992 Lovinger DM, Harrison NL, Lambert NA. The actions of 3-aminopropanephosphinic acid at GABAB receptors in rat hippocampus. European Journal of Pharmacology. 211: 337-41. PMID 1319911 DOI: 10.1016/0014-2999(92)90390-P  0.487
1992 Lovinger DM, Harrison NL, Jones MV, Zimmerman SA. TRICHLOROETHANOL POTENTIATION OF GABAA RECEPTOR-MEDIATED ION CURRENT AND INHIBITORY SYNAPTIC CURRENT IN HIPPOCAMPAL NEURONS Anesthesiology. 77: A762. DOI: 10.1097/00000542-199209001-00762  0.421
1992 Zimmerman SA, Schwartz EB, Talukder G, Harrison NL. METHOHEXITAL (BREVITAL) AND CHLOROFORM ENHANCE GABA-ACTIVATED CHLORIDE CURRENTS IN CULTURED RAT HIPPOCAMPAL NEURONS AT CLINICALLY RELEVANT CONCENTRATIONS Anesthesiology. 77: A702. DOI: 10.1097/00000542-199209001-00702  0.31
1992 Hales TG, Jones MV, Harrison NL. EVIDENCE FOR SUBUNIT DEPENDENT DIRECT ACTIVATION OF THE GABAA RECEPTOR BY ISOFLURANE Anesthesiology. 77: A698. DOI: 10.1097/00000542-199209001-00698  0.441
1992 Harrison NL, Brooks PA, Hornberger LA, Radke HK, Jones MV. The effects of some volatile anaesthetics on responses to exogenous GABA and inhibitory postsynaptic currents in cultured rat hippocampal neurons Journal of Physiology. 446: 258P.  0.328
1991 Lambert NA, Harrison NL, Teyler TJ. Baclofen-induced disinhibition in area CA1 of rat hippocampus is resistant to extracellular Ba2+. Brain Research. 547: 349-52. PMID 1679368 DOI: 10.1016/0006-8993(91)90985-5  0.373
1991 Lambert NA, Harrison NL, Teyler TJ. Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus. Neuroscience Letters. 124: 101-4. PMID 1677456 DOI: 10.1016/0304-3940(91)90831-D  0.366
1991 Harrison NL, Jones MV, Brooks PA. THREE VOLATILE ANESTHETICS ENHANCE GABA-ACTIVATED CHLORIDE CURRENTS IN CULTURED RAT HIPPOCAMPAL NEURONS AT CLINICALLY RELEVANT CONCENTRATIONS Anesthesiology. 75: A1040. DOI: 10.1097/00000542-199109001-01039  0.425
1991 Jones MV, Hornberger LA, Harrison NL. CLINICAL CONCENTRATIONS OF THREE VOLATILE ANESTHETICS PROLONG GABA-MEDIATED INHIBITORY POSTSYNAPTIC CURRENTS AT SYNAPSES BETWEEN CULTURED RAT HIPPOCAMPAL NEURONS Anesthesiology. 75: A580. DOI: 10.1097/00000542-199109001-00579  0.321
1990 Harrison NL, Lovinger DM, Lambert NA, Teyler TJ, Prager R, Ong J, Kerr DI. The actions of 2-hydroxy-saclofen at presynaptic GABAB receptors in the rat hippocampus. Neuroscience Letters. 119: 272-6. PMID 2177868 DOI: 10.1016/0304-3940(90)90851-Y  0.429
1990 Ong J, Harrison NL, Hall RG, Barker JL, Johnston GA, Kerr DI. 3-Aminopropanephosphinic acid is a potent agonist at peripheral and central presynaptic GABAB receptors. Brain Research. 526: 138-42. PMID 1964105 DOI: 10.1016/0006-8993(90)90260-I  0.658
1990 Lambert NA, Harrison NL. Analogs of cyclic AMP decrease gamma-aminobutyric acidA receptor-mediated chloride current in cultured rat hippocampal neurons via an extracellular site. The Journal of Pharmacology and Experimental Therapeutics. 255: 90-4. PMID 1698973  0.386
1990 Jones MV, Brooks PA, Harrison NL. A710 ENHANCEMENT OF GABA-ACTIVATED CHLORIDE CONDUCTANCE IN CULTURED RAT HIPPOCAMPAL NEURONS BY ENFLURANE Anesthesiology. 73: NA. DOI: 10.1097/00000542-199009001-00708  0.399
1989 Lambert NA, Harrison NL, Kerr DI, Ong J, Prager RH, Teyler TJ. Blockade of the late IPSP in rat CA1 hippocampal neurons by 2-hydroxy-saclofen. Neuroscience Letters. 107: 125-8. PMID 2559366 DOI: 10.1016/0304-3940(89)90803-3  0.451
1989 Harrison NL, Lambert NA. Modification of GABAA receptor function by an analog of cyclic AMP. Neuroscience Letters. 105: 137-42. PMID 2484725 DOI: 10.1016/0304-3940(89)90025-6  0.405
1989 Harrison NL, Meyers DE, Owen DG, Barker JL. MECHANISTIC STUDIES OK ANESTHETIC STEROIDS AND BARBITURATES Anesthesiology. 71: A594. DOI: 10.1097/00000542-198909001-00594  0.495
1988 Silva NL, Mariani AP, Harrison NL, Barker JL. 5,7-Dihydroxytryptamine identifies living dopaminergic neurons in mesencephalic cultures. Proceedings of the National Academy of Sciences of the United States of America. 85: 7346-50. PMID 3050994  0.458
1988 Barker JL, Harrison NL. Outward rectification of inhibitory postsynaptic currents in cultured rat hippocampal neurones. The Journal of Physiology. 403: 41-55. PMID 2908121  0.52
1988 Harrison NL, Lange GD, Barker JL. Pre- and post-synaptic aspects of GABA-mediated synaptic inhibition in cultured rat hippocampal neurons. Advances in Biochemical Psychopharmacology. 45: 73-85. PMID 2902747  0.526
1988 Harrison NL, Lange GD, Barker JL. (-)-Baclofen activates presynaptic GABAB receptors on GABAergic inhibitory neurons from embryonic rat hippocampus. Neuroscience Letters. 85: 105-9. PMID 2834671 DOI: 10.1016/0304-3940(88)90437-5  0.601
1987 Harrison NL, Vicini S, Barker JL. A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 604-9. PMID 3819824 DOI: 10.1523/Jneurosci.07-02-00604.1987  0.587
1987 Harrison NL, Majewska MD, Harrington JW, Barker JL. Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex. The Journal of Pharmacology and Experimental Therapeutics. 241: 346-53. PMID 3033209  0.621
1987 Barker JL, Harrison NL, Lange GD, Owen DG. Potentiation of gamma-aminobutyric-acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones. The Journal of Physiology. 386: 485-501. PMID 2445967 DOI: 10.1113/Jphysiol.1987.Sp016547  0.648
1987 Barker JL, Dufy B, Harrison NL, Owen DG, MacDonald JF. Signal transduction mechanisms in cultured CNS neurons and clonal pituitary cells. Neuropharmacology. 26: 941-55. PMID 2443868 DOI: 10.1016/0028-3908(87)90073-6  0.643
1987 Barker JL, Dufy B, Harrington JW, Harrison NL, MacDermott AB, MacDonald JF, Owen DG, Vicini S. Signals transduced by gamma-aminobutyric acid in cultured central nervous system neurons and thyrotropin releasing hormone in clonal pituitary cells. Annals of the New York Academy of Sciences. 494: 1-38. PMID 2440362 DOI: 10.1111/J.1749-6632.1987.Tb29477.X  0.6
1987 Harrison NL. Progesterone metabolites enhance GABA activities Trends in Pharmacological Sciences. 8: 334. DOI: 10.1016/0165-6147(87)90139-8  0.45
1986 Horne AL, Harrison NL, Turner JP, Simmonds MA. Spontaneous paroxysmal activity induced by zero magnesium and bicuculline: suppression by NMDA antagonists and GABA mimetics. European Journal of Pharmacology. 122: 231-8. PMID 3519245 DOI: 10.1016/0014-2999(86)90107-X  0.694
1986 Barker JL, Harrison NL, Meyers DE, Majewska MD. Steroid modulation of GABAA receptor-coupled Cl- conductance. Clinical Neuropharmacology. 9: 392-4. PMID 2436770  0.506
1986 Barker JL, Harrison NL, Mariani AP. Benzodiazepine pharmacology of cultured mammalian CNS neurons. Life Sciences. 39: 1959-68. PMID 2431243 DOI: 10.1016/0024-3205(86)90319-X  0.621
1986 Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science (New York, N.Y.). 232: 1004-7. PMID 2422758 DOI: 10.1126/Science.2422758  0.664
1985 Harrison NL, Simmonds MA. Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. British Journal of Pharmacology. 84: 381-91. PMID 2858237 DOI: 10.1111/J.1476-5381.1985.Tb12922.X  0.589
1984 Harrison NL, Simmonds MA. Modulation of the GABA receptor complex by a steroid anaesthetic. Brain Research. 323: 287-92. PMID 6098342 DOI: 10.1016/0006-8993(84)90299-3  0.687
1984 Simmonds MA, Turner JP, Harrison NL. Interactions of steroids with the GABA-A receptor complex Neuropharmacology. 23: 877-878. DOI: 10.1016/0028-3908(84)90290-9  0.674
1983 Harrison NL, Simmonds MA. Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro. British Journal of Pharmacology. 80: 387-94. PMID 6317133 DOI: 10.1111/J.1476-5381.1983.Tb10045.X  0.647
1983 Harrison NL, Simmonds MA. The picrotoxin-like action of a convulsant benzodiazepine, Ro5-3663. European Journal of Pharmacology. 87: 155-8. PMID 6301850 DOI: 10.1016/0014-2999(83)90064-X  0.662
1982 Harrison NL, Simmonds MA. Sodium valproate enhances responses to GABA receptor activation only at high concentrations. Brain Research. 250: 201-4. PMID 6291721 DOI: 10.1016/0006-8993(82)90971-4  0.678
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