Pierre-Olivier Fernagut - Publications

Institute of Neurodegenerative Diseases Université de Bordeaux, Talence, Nouvelle-Aquitaine, France 

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lopez-Cuina M, Guérin P, Dutheil N, Martin C, Lasserre TL, Fernagut PO, Meissner WG, Bezard E. GRK2-Targeted Knockdown as Therapy for Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 37093618 DOI: 10.1002/mds.29422  0.412
2023 Decourt M, Balado E, Francheteau M, Solinas M, Benoît-Marand M, Fernagut PO. Premorbid performances determine the deleterious effects of nigrostriatal degeneration and pramipexole on behavioural flexibility. Npj Parkinson's Disease. 9: 31. PMID 36859454 DOI: 10.1038/s41531-023-00475-3  0.367
2021 Mallet D, Dufourd T, Decourt M, Carcenac C, Bossù P, Verlin L, Fernagut PO, Benoit-Marand M, Spalletta G, Barbier EL, Carnicella S, Sgambato V, Fauvelle F, Boulet S. A metabolic biomarker for early stage of Parkinson's disease in patients and animal models. The Journal of Clinical Investigation. PMID 34914634 DOI: 10.1172/JCI146400  0.373
2021 Theis H, Probst C, Fernagut PO, van Eimeren T. Unlucky punches: the vulnerability-stress model for the development of impulse control disorders in Parkinson's disease. Npj Parkinson's Disease. 7: 112. PMID 34880241 DOI: 10.1038/s41531-021-00253-z  0.321
2021 Bassil F, Delamarre A, Canron MH, Dutheil N, Vital A, Négrier-Leibreich ML, Bezard E, Fernagut PO, Meissner WG. Impaired brain insulin signalling in Parkinson's disease. Neuropathology and Applied Neurobiology. PMID 34405431 DOI: 10.1111/nan.12760  0.516
2021 Decourt M, Jiménez-Urbieta H, Benoit-Marand M, Fernagut PO. Neuropsychiatric and Cognitive Deficits in Parkinson's Disease and Their Modeling in Rodents. Biomedicines. 9. PMID 34204380 DOI: 10.3390/biomedicines9060684  0.37
2021 Sun X, Yu X, Zhang L, Zhao W, Wang M, Zhang Y, Li X, Gao R, Breger LS, Dovero S, Porras G, Fernagut PO, Dehay B, Bezard E, Qin C. Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE. Heliyon. 7: e06302. PMID 33665452 DOI: 10.1016/j.heliyon.2021.e06302  0.509
2021 Fridjonsdottir E, Shariatgorji R, Nilsson A, Vallianatou T, Odell LR, Schembri LS, Svenningsson P, Fernagut PO, Crossman AR, Bezard E, Andrén PE. Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia. Science Advances. 7. PMID 33523980 DOI: 10.1126/sciadv.abe5948  0.537
2020 Deffains M, Canron MH, Teil M, Li Q, Dehay B, Bezard E, Fernagut PO. L-DOPA regulates α-synuclein accumulation in experimental parkinsonism. Neuropathology and Applied Neurobiology. PMID 33275784 DOI: 10.1111/nan.12678  0.596
2020 Yu Z, Shi M, Stewart T, Fernagut PO, Huang Y, Tian C, Dehay B, Atik A, Yang D, De Giorgi F, Ichas F, Canron MH, Ceravolo R, Frosini D, Kim HJ, et al. Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction. Brain : a Journal of Neurology. PMID 32428221 DOI: 10.1093/Brain/Awaa110  0.416
2020 Lopez-Cuina M, Guerin PA, Canron MH, Delamarre A, Dehay B, Bezard E, Meissner WG, Fernagut PO. Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32291831 DOI: 10.1002/Mds.28034  0.618
2019 Meissner WG, Fernagut PO, Dehay B, Péran P, Traon AP, Foubert-Samier A, Lopez Cuina M, Bezard E, Tison F, Rascol O. Multiple System Atrophy: Recent Developments and Future Perspectives. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31692132 DOI: 10.1002/Mds.27894  0.594
2019 Arotcarena ML, Bourdenx M, Dutheil N, Thiolat ML, Doudnikoff E, Dovero S, Ballabio A, Fernagut PO, Meissner WG, Bezard E, Dehay B. Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies. Jci Insight. 4. PMID 31434803 DOI: 10.1172/Jci.Insight.129719  0.633
2019 Fernagut PO. Dopamine and eating behavior disorders in Parkinson's disease: A complex recipe. Movement Disorders : Official Journal of the Movement Disorder Society. 34: 767-768. PMID 31206832 DOI: 10.1002/Mds.27703  0.411
2019 Li Q, Fernagut PO, Bezard E. l-Dopa-free learned dyskinetic behavior in a Parkinson's primate model. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31083822 DOI: 10.1002/Mds.27715  0.55
2018 Jiménez-Urbieta H, Gago B, Quiroga-Varela A, Rodríguez-Chinchilla T, Merino-Galán L, Oregi A, Belloso-Iguerategui A, Delgado-Alvarado M, Navalpotro-Gómez I, Marin C, Fernagut PO, Rodríguez-Oroz MC. Pramipexole-induced impulsivity in mildparkinsonian rats: a model of impulse control disorders in Parkinson's disease. Neurobiology of Aging. 75: 126-135. PMID 30572183 DOI: 10.1016/J.Neurobiolaging.2018.11.021  0.5
2018 Lopez-Cuina M, Fernagut PO, Canron MH, Vital A, Lannes B, De Paula AM, Streichenberger N, Guehl D, Damier P, Eusebio A, Houeto JL, Tison F, Tranchant C, Viallet F, Witjas T, et al. Deep brain stimulation does not enhance neuroinflammation in multiple system atrophy. Neurobiology of Disease. 118: 155-160. PMID 30026036 DOI: 10.1016/J.Nbd.2018.07.016  0.453
2018 Al Sagheer T, Haida O, Balbous A, Francheteau M, Matas E, Fernagut PO, Jaber M. Motor impairments correlate with social deficits and restricted neuronal loss in an environmental model of autism. The International Journal of Neuropsychopharmacology. PMID 29762671 DOI: 10.1093/Ijnp/Pyy043  0.335
2018 Marques A, Durif F, Fernagut PO. Impulse control disorders in Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29511827 DOI: 10.1007/S00702-018-1870-8  0.498
2017 Bassil F, Guerin PA, Dutheil N, Li Q, Klugmann M, Meissner WG, Bezard E, Fernagut PO. Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28556404 DOI: 10.1002/Mds.27041  0.648
2017 Bastide MF, Glangetas C, Doudnikoff E, Li Q, Bourdenx M, Fernagut PO, Dumont ÉC, Georges F, Bézard E. Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia. Scientific Reports. 7: 2348. PMID 28539659 DOI: 10.1038/S41598-017-02572-9  0.636
2017 Soria FN, Engeln M, Martinez-Vicente M, Glangetas C, López-González MJ, Dovero S, Dehay B, Normand E, Vila M, Favereaux A, Georges F, Lo Bianco C, Bezard E, Fernagut PO. Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration. Human Molecular Genetics. PMID 28520872 DOI: 10.1093/Hmg/Ddx120  0.77
2017 Laurens B, Vergnet S, Lopez MC, Foubert-Samier A, Tison F, Fernagut PO, Meissner WG. Multiple System Atrophy - State of the Art. Current Neurology and Neuroscience Reports. 17: 41. PMID 28378233 DOI: 10.1007/S11910-017-0751-0  0.432
2017 Bassil F, Canron MH, Vital A, Bezard E, Li Y, Greig NH, Gulyani S, Kapogiannis D, Fernagut PO, Meissner WG. Insulin resistance and exendin-4 treatment for multiple system atrophy. Brain : a Journal of Neurology. PMID 28334990 DOI: 10.1093/Brain/Awx044  0.522
2017 Voon V, Napier TC, Frank MJ, Sgambato-Faure V, Grace AA, Rodriguez-Oroz M, Obeso J, Bezard E, Fernagut PO. Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update. The Lancet. Neurology. 16: 238-250. PMID 28229895 DOI: 10.1016/S1474-4422(17)30004-2  0.611
2016 Bassil F, Fernagut PO, Bezard E, Pruvost A, Leste-Lasserre T, Hoang QQ, Ringe D, Petsko GA, Meissner WG. Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482103 DOI: 10.1073/Pnas.1609291113  0.583
2016 Engeln M, Ansquer S, Dugast E, Bezard E, Belin D, Fernagut PO. Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy. Neuropharmacology. PMID 27216859 DOI: 10.1016/J.Neuropharm.2016.05.013  0.787
2016 Dehay B, Decressac M, Bourdenx M, Guadagnino I, Fernagut PO, Tamburrino A, Bassil F, Meissner WG, Bezard E. Targeting α-synuclein: Therapeutic options. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26926119 DOI: 10.1002/Mds.26568  0.618
2016 Arcuri L, Viaro R, Bido S, Longo F, Calcagno M, Fernagut PO, Zaveri NT, Calò G, Bezard E, Morari M. Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease. Neurobiology of Disease. PMID 26804029 DOI: 10.1016/J.Nbd.2016.01.016  0.64
2015 Perez-Lloret S, Flabeau O, Fernagut PO, Pavy-Le Traon A, Rey MV, Foubert-Samier A, Tison F, Rascol O, Meissner WG. Current Concepts in the Treatment of Multiple System Atrophy. Movement Disorders Clinical Practice. 2: 6-16. PMID 30363880 DOI: 10.1002/Mdc3.12145  0.339
2015 Bassil F, Monvoisin A, Canron MH, Vital A, Meissner WG, Tison F, Fernagut PO. Region-Specific Alterations of Matrix Metalloproteinase Activity in Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26260627 DOI: 10.1002/Mds.26329  0.375
2015 Bastide MF, Meissner WG, Picconi B, Fasano S, Fernagut PO, Feyder M, Francardo V, Alcacer C, Ding Y, Brambilla R, Fisone G, Jon Stoessl A, Bourdenx M, Engeln M, Navailles S, et al. Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease. Progress in Neurobiology. PMID 26209473 DOI: 10.1016/J.Pneurobio.2015.07.002  0.771
2015 Bourdenx M, Dovero S, Engeln M, Bido S, Bastide MF, Dutheil N, Vollenweider I, Baud L, Piron C, Grouthier V, Boraud T, Porras G, Li Q, Baekelandt V, Scheller D, ... ... Fernagut PO, et al. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression. Acta Neuropathologica Communications. 3: 46. PMID 26205255 DOI: 10.1186/S40478-015-0222-2  0.791
2014 Bastide MF, de la Crompe B, Doudnikoff E, Fernagut PO, Gross CE, Mallet N, Boraud T, Bézard E. Inhibiting Lateral Habenula Improves L-DOPA-induced Dyskinesia. Biological Psychiatry. PMID 25442003 DOI: 10.1016/J.Biopsych.2014.08.022  0.539
2014 Engeln M, Bastide MF, Toulmé E, Dehay B, Bourdenx M, Doudnikoff E, Li Q, Gross CE, Boué-Grabot E, Pisani A, Bezard E, Fernagut PO. Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-Dopa-Induced Dyskinesia. Biological Psychiatry. PMID 25146322 DOI: 10.1016/J.Biopsych.2014.07.007  0.76
2014 Engeln M, De Deurwaerdère P, Li Q, Bezard E, Fernagut PO. Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia. Cerebral Cortex (New York, N.Y. : 1991). PMID 24770706 DOI: 10.1093/cercor/bhu076  0.765
2014 Fernagut PO, Dehay B, Maillard A, Bezard E, Perez P, Pavy-Le Traon A, Rascol O, Foubert-Samier A, Tison F, Meissner WG. Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies. Neurobiology of Disease. 67: 133-9. PMID 24727096 DOI: 10.1016/J.Nbd.2014.03.021  0.61
2014 Vitrac C, Péron S, Frappé I, Fernagut PO, Jaber M, Gaillard A, Benoit-Marand M. Dopamine control of pyramidal neuron activity in the primary motor cortex via D2 receptors. Frontiers in Neural Circuits. 8: 13. PMID 24616667 DOI: 10.3389/Fncir.2014.00013  0.361
2014 Bassil F, Fernagut PO, Bezard E, Meissner WG. Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification? Progress in Neurobiology. 118: 1-18. PMID 24582776 DOI: 10.1016/J.Pneurobio.2014.02.005  0.551
2014 Flabeau O, Meissner WG, Ozier A, Berger P, Tison F, Fernagut PO. Breathing variability and brainstem serotonergic loss in a genetic model of multiple system atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 388-95. PMID 24442757 DOI: 10.1002/Mds.25804  0.346
2014 Bezard E, Fernagut PO. Premotor parkinsonism models. Parkinsonism & Related Disorders. 20: S17-9. PMID 24262174 DOI: 10.1016/S1353-8020(13)70007-5  0.552
2014 Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Annals of Neurology. 75: 351-62. PMID 24243558 DOI: 10.1002/Ana.24066  0.646
2014 Bastide MF, Dovero S, Charron G, Porras G, Gross CE, Fernagut PO, Bézard E. Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia. Neurobiology of Disease. 62: 179-92. PMID 24103779 DOI: 10.1016/J.Nbd.2013.09.020  0.463
2013 Engeln M, Fasano S, Ahmed SH, Cador M, Baekelandt V, Bezard E, Fernagut PO. Levodopa gains psychostimulant-like properties after nigral dopaminergic loss. Annals of Neurology. 74: 140-4. PMID 23494678 DOI: 10.1002/Ana.23881  0.786
2013 Engeln M, Ahmed SH, Vouillac C, Tison F, Bezard E, Fernagut PO. Reinforcing properties of Pramipexole in normal and parkinsonian rats. Neurobiology of Disease. 49: 79-86. PMID 22940424 DOI: 10.1016/J.Nbd.2012.08.005  0.755
2012 Fernagut PO, Vital A, Canron MH, Tison F, Meissner WG. Ambiguous mechanisms of dysphagia in multiple system atrophy. Brain : a Journal of Neurology. 135: e205; author reply e. PMID 21824966 DOI: 10.1093/Brain/Awr185  0.349
2011 Fantin M, Morari M, Tison F, Fernagut PO. NR2B subunit blockade does not affect motor symptoms induced by 3-nitropropionic acid. Neurological Research. 33: 444-7. PMID 21535946 DOI: 10.1179/1743132810Y.0000000002  0.333
2011 Leger F, Fernagut PO, Canron MH, Léoni S, Vital C, Tison F, Bezard E, Vital A. Protein aggregation in the aging retina. Journal of Neuropathology and Experimental Neurology. 70: 63-8. PMID 21157377 DOI: 10.1097/Nen.0B013E31820376Cc  0.495
2010 Fernagut PO, Li Q, Dovero S, Chan P, Wu T, Ravenscroft P, Hill M, Chen Z, Bezard E. Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. Plos One. 5: e14053. PMID 21124922 DOI: 10.1371/Journal.Pone.0014053  0.6
2010 Fernagut PO, Barraud Q, Bezard E, Ghorayeb I, Tison F. Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism. Neurological Research. 32: 1050-3. PMID 20810027 DOI: 10.1179/016164110X12807570509934  0.633
2009 Voon V, Fernagut PO, Wickens J, Baunez C, Rodriguez M, Pavon N, Juncos JL, Obeso JA, Bezard E. Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders. The Lancet. Neurology. 8: 1140-9. PMID 19909912 DOI: 10.1016/S1474-4422(09)70287-X  0.606
2009 Vital A, Fernagut PO, Canron MH, Joux J, Bezard E, Martin-Negrier ML, Vital C, Tison F. The nigrostriatal pathway in Creutzfeldt-Jakob disease. Journal of Neuropathology and Experimental Neurology. 68: 809-15. PMID 19535991 DOI: 10.1097/Nen.0B013E3181Abdae8  0.606
2008 Chou AP, Maidment N, Klintenberg R, Casida JE, Li S, Fitzmaurice AG, Fernagut PO, Mortazavi F, Chesselet MF, Bronstein JM. Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome. The Journal of Biological Chemistry. 283: 34696-703. PMID 18818210 DOI: 10.1074/Jbc.M802210200  0.476
2005 Fleming SM, Fernagut PO, Chesselet MF. Genetic mouse models of parkinsonism: strengths and limitations. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 495-503. PMID 16389313 DOI: 10.1602/Neurorx.2.3.495  0.518
2005 Fernagut PO, Ghorayeb I, Diguet E, Tison F. In vivo models of multiple system atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. 20: S57-63. PMID 16092092 DOI: 10.1002/Mds.20541  0.43
2005 Chesselet MF, Fernagut PO, Fleming S. Parkinson's disease models: From toxins to genes Drug Discovery Today: Disease Models. 2: 299-303. DOI: 10.1016/J.Ddmod.2005.11.008  0.469
2004 Fleming SM, Salcedo J, Fernagut PO, Rockenstein E, Masliah E, Levine MS, Chesselet MF. Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9434-40. PMID 15496679 DOI: 10.1523/Jneurosci.3080-04.2004  0.407
2004 Fernagut PO, Chesselet MF. Alpha-synuclein and transgenic mouse models. Neurobiology of Disease. 17: 123-30. PMID 15474350 DOI: 10.1016/J.Nbd.2004.07.001  0.404
2004 Zhu C, Vourc'h P, Fernagut PO, Fleming SM, Lacan S, Dicarlo CD, Seaman RL, Chesselet MF. Variable effects of chronic subcutaneous administration of rotenone on striatal histology. The Journal of Comparative Neurology. 478: 418-26. PMID 15384065 DOI: 10.1002/Cne.20305  0.397
2004 Diguet E, Fernagut PO, Wei X, Du Y, Rouland R, Gross C, Bezard E, Tison F. Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease. The European Journal of Neuroscience. 19: 3266-76. PMID 15217383 DOI: 10.1111/j.0953-816X.2004.03372.x  0.531
2004 Fleming SM, Zhu C, Fernagut PO, Mehta A, DiCarlo CD, Seaman RL, Chesselet MF. Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone. Experimental Neurology. 187: 418-29. PMID 15144868 DOI: 10.1016/J.Expneurol.2004.01.023  0.4
2004 Diguet E, Fernagut PO, Normand E, Centelles L, Mulle C, Tison F. Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history. Neurobiology of Disease. 15: 667-75. PMID 15056475 DOI: 10.1016/J.Nbd.2003.12.010  0.351
2003 Stefanova N, Puschban Z, Fernagut PO, Brouillet E, Tison F, Reindl M, Jellinger KA, Poewe W, Wenning GK. Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy). Acta Neuropathologica. 106: 157-66. PMID 12764627 DOI: 10.1007/S00401-003-0717-Y  0.321
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