Benjamin Dehay - Publications

Affiliations: 
Université de Bordeaux, Talence, Nouvelle-Aquitaine, France 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Arotcarena ML, Bourdenx M, Dutheil N, Thiolat ML, Doudnikoff E, Dovero S, Ballabio A, Fernagut PO, Meissner WG, Bezard E, Dehay B. Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies. Jci Insight. 4. PMID 31434803 DOI: 10.1172/jci.insight.129719  0.84
2018 Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, Martella G, Meringolo M, Dehay B, Doudnikoff E, Zachariou V, Goodchild RE, Mercuri NB, D'Amelio M, Pasqualetti M, et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models. Embo Molecular Medicine. PMID 30552094 DOI: 10.15252/emmm.201809283  0.84
2018 Prevot G, Soria FN, Thiolat ML, Daniel J, Verlhac JB, Blanchard-Desce M, Bezard E, Barthelemy P, Crauste-Manciet S, Dehay B. Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases. Bioconjugate Chemistry. PMID 30424597 DOI: 10.1021/acs.bioconjchem.8b00697  0.84
2018 Chansel-Debordeaux L, Bourdenx M, Dutheil N, Dovero S, Canron MH, Jimenez C, Bezard E, Dehay B. Systemic gene delivery by single-dose intracardiac administration of scAAV2/9 and scAAV2/rh10 variants in newborn rats. Human Gene Therapy Methods. PMID 30064266 DOI: 10.1089/hgtb.2017.192.r3  0.84
2017 Perez-Villalba A, Salomé Sirerol-Piquer M, Belenguer G, Soriano-Cantón R, Belén Muñoz-Manchado A, Villadiego J, Alarcón-Arís D, Soria FN, Dehay B, Bezard E, Vila M, Bortolozzi A, José Toledo-Aral J, Pérez-Sánchez F, Fariñas I. Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29217686 DOI: 10.1523/JNEUROSCI.2276-17.2017  0.84
2017 Soria FN, Engeln M, Martinez-Vicente M, Glangetas C, López-González MJ, Dovero S, Dehay B, Normand E, Vila M, Favereaux A, Georges F, Lo Bianco C, Bezard E, Fernagut PO. Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration. Human Molecular Genetics. PMID 28520872 DOI: 10.1093/hmg/ddx120  0.84
2017 Cavaliere F, Cerf L, Dehay B, Ramos-Gonzalez P, De Giorgi F, Bourdenx M, Bessede A, Obeso JA, Matute C, Ichas F, Bezard E. In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains. Neurobiology of Disease. 103: 101-112. PMID 28411117 DOI: 10.1016/j.nbd.2017.04.011  0.84
2017 Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ. U18666A, an Activator of Sterol Regulatory Element Binding Protein (SREBP) Pathway Modulates Presynaptic Dopaminergic Phenotype of SH-SY5Y Neuroblastoma Cells. Synapse (New York, N.Y.). PMID 28407359 DOI: 10.1002/syn.21980  0.84
2017 Bourdenx M, Dovero S, Thiolat ML, Bezard E, Dehay B. Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model. Scientific Reports. 7: 45831. PMID 28374864 DOI: 10.1038/srep45831  0.84
2017 Bourdenx M, Dehay B. [Autophagy and brain: the case of neurodegenerative diseases]. Medecine Sciences : M/S. 33: 268-274. PMID 28367813 DOI: 10.1051/medsci/20173303013  0.84
2017 Soria FN, Pampliega O, Bourdenx M, Meissner WG, Bezard E, Dehay B. Exosomes, an Unmasked Culprit in Neurodegenerative Diseases. Frontiers in Neuroscience. 11: 26. PMID 28197068 DOI: 10.3389/fnins.2017.00026  0.84
2017 Ysselstein D, Dehay B, Costantino IM, McCabe GP, Frosch MP, George JM, Bezard E, Rochet JC. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity. Acta Neuropathologica Communications. 5: 3. PMID 28069058 DOI: 10.1186/s40478-016-0403-7  0.84
2016 Bourdenx M, Dehay B. What lysosomes actually tell us about Parkinson's disease? Ageing Research Reviews. 32: 140-149. PMID 26947123 DOI: 10.1016/j.arr.2016.02.008  0.84
2016 Dehay B, Decressac M, Bourdenx M, Guadagnino I, Fernagut PO, Tamburrino A, Bassil F, Meissner WG, Bezard E. Targeting α-synuclein: Therapeutic options. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26926119 DOI: 10.1002/mds.26568  0.84
2016 Bourdenx M, Daniel J, Genin E, Soria FN, Blanchard-Desce M, Bezard E, Dehay B. Nanoparticles restore lysosomal acidification defects: Implication for Parkinson and other lysosomal-related diseases. Autophagy. 0. PMID 26761717 DOI: 10.1080/15548627.2015.1136769  0.84
2015 Bourdenx M, Dehay B, Bezard' E. Experimental modelling of -synuclein aggregation and spreading in synucleinopathies. Bulletin De L'Academie Nationale De Medecine. 199: 797-808. PMID 29901880  0.84
2015 Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ. Harnessing the Trophic and Modulatory Potential of Statins in a Dopaminergic Cell Line. Synapse (New York, N.Y.). PMID 26695835 DOI: 10.1002/syn.21881  0.84
2015 Dehay B, Vila M, Bezard E, Brundin P, Kordower JH. Alpha-synuclein propagation: New insights from animal models. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26347034 DOI: 10.1002/mds.26370  0.84
2015 Bourdenx M, Koulakiotis NS, Sanoudou D, Bezard E, Dehay B, Tsarbopoulos A. Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies. Progress in Neurobiology. PMID 26209472 DOI: 10.1016/j.pneurobio.2015.07.003  0.84
2015 Bourdenx M, Dovero S, Engeln M, Bido S, Bastide MF, Dutheil N, Vollenweider I, Baud L, Piron C, Grouthier V, Boraud T, Porras G, Li Q, Baekelandt V, Scheller D, ... ... Dehay B, et al. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression. Acta Neuropathologica Communications. 3: 46. PMID 26205255 DOI: 10.1186/s40478-015-0222-2  0.84
2015 Dehay B, Bourdenx M, Gorry P, Przedborski S, Vila M, Hunot S, Singleton A, Olanow CW, Merchant KM, Bezard E, Petsko GA, Meissner WG. Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations. The Lancet. Neurology. PMID 26050140 DOI: 10.1016/S1474-4422(15)00006-X  0.84
2014 Bourdenx M, Dehay B, Bezard E. Down-regulating α-synuclein for treating synucleopathies. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1463-5. PMID 25214445 DOI: 10.1002/mds.26028  0.84
2014 Bourdenx M, Bezard E, Dehay B. Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. Frontiers in Neuroanatomy. 8: 83. PMID 25177278 DOI: 10.3389/fnana.2014.00083  0.84
2014 Engeln M, Bastide MF, Toulmé E, Dehay B, Bourdenx M, Doudnikoff E, Li Q, Gross CE, Boué-Grabot E, Pisani A, Bezard E, Fernagut PO. Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-Dopa-Induced Dyskinesia. Biological Psychiatry. PMID 25146322 DOI: 10.1016/j.biopsych.2014.07.007  0.84
2014 Bourdenx M, Dutheil N, Bezard E, Dehay B. Systemic gene delivery to the central nervous system using Adeno-associated virus. Frontiers in Molecular Neuroscience. 7: 50. PMID 24917785 DOI: 10.3389/fnmol.2014.00050  0.84
2014 Fernagut PO, Dehay B, Maillard A, Bezard E, Perez P, Pavy-Le Traon A, Rascol O, Foubert-Samier A, Tison F, Meissner WG. Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies. Neurobiology of Disease. 67: 133-9. PMID 24727096 DOI: 10.1016/j.nbd.2014.03.021  0.84
2014 Bové J, Martínez-Vicente M, Dehay B, Perier C, Recasens A, Bombrun A, Antonsson B, Vila M. BAX channel activity mediates lysosomal disruption linked to Parkinson disease. Autophagy. 10: 889-900. PMID 24686337 DOI: 10.4161/auto.28286  0.44
2014 Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Annals of Neurology. 75: 351-62. PMID 24243558 DOI: 10.1002/ana.24066  0.84
2013 Dehay B, Martinez-Vicente M, Caldwell GA, Caldwell KA, Yue Z, Cookson MR, Klein C, Vila M, Bezard E. Lysosomal impairment in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 725-32. PMID 23580333 DOI: 10.1002/mds.25462  0.84
2012 Canron MH, Perret M, Vital A, Bézard E, Dehay B. Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate. Scientific Reports. 2: 910. PMID 23205271 DOI: 10.1038/srep00910  0.84
2012 Porras G, Berthet A, Dehay B, Li Q, Ladepeche L, Normand E, Dovero S, Martinez A, Doudnikoff E, Martin-Négrier ML, Chuan Q, Bloch B, Choquet D, Boué-Grabot E, Groc L, et al. PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking. The Journal of Clinical Investigation. 122: 3977-89. PMID 23041629 DOI: 10.1172/JCI59426  0.84
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Dehay B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490  0.44
2012 Dehay B, Martinez-Vicente M, Ramirez A, Perier C, Klein C, Vila M, Bezard E. Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove. Autophagy. 8: 1389-91. PMID 22885599 DOI: 10.4161/auto.21011  0.84
2012 Dehay B, Ramirez A, Martinez-Vicente M, Perier C, Canron MH, Doudnikoff E, Vital A, Vila M, Klein C, Bezard E. Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 9611-6. PMID 22647602 DOI: 10.1073/pnas.1112368109  0.84
2012 Dehay B, Dalkara D, Dovero S, Li Q, Bezard E. Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques. Scientific Reports. 2: 253. PMID 22355765 DOI: 10.1038/srep00253  0.84
2012 Berthet A, Bezard E, Porras G, Fasano S, Barroso-Chinea P, Dehay B, Martinez A, Thiolat ML, Nosten-Bertrand M, Giros B, Baufreton J, Li Q, Bloch B, Martin-Negrier ML. L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 681-91. PMID 22238104 DOI: 10.1523/JNEUROSCI.1541-11.2012  0.84
2011 Dehay B, Bezard E. New animal models of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1198-1205. PMID 22046592 DOI: 10.1002/mds.23546  0.84
2011 Vila M, Bové J, Dehay B, Rodríguez-Muela N, Boya P. Lysosomal membrane permeabilization in Parkinson disease. Autophagy. 7: 98-100. PMID 21045565  0.44
2010 Dehay B, Bové J, Rodríguez-Muela N, Perier C, Recasens A, Boya P, Vila M. Pathogenic lysosomal depletion in Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12535-44. PMID 20844148 DOI: 10.1523/JNEUROSCI.1920-10.2010  0.44
2010 Perier C, Bové J, Dehay B, Jackson-Lewis V, Rabinovitch PS, Przedborski S, Vila M. Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins. Annals of Neurology. 68: 184-92. PMID 20695011 DOI: 10.1002/ana.22034  0.84
2007 Perier C, Bové J, Wu DC, Dehay B, Choi DK, Jackson-Lewis V, Rathke-Hartlieb S, Bouillet P, Strasser A, Schulz JB, Przedborski S, Vila M. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 8161-6. PMID 17483459 DOI: 10.1073/pnas.0609874104  0.84
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