Charles A. Haynes - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Biomedical Engineering

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kalathottukaren MT, Creagh AL, Abbina S, Lu G, Karbarz MJ, Pandey A, Conley PB, Kizhakkedathu JN, Haynes C. Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors. Blood Advances. 2: 2104-2114. PMID 30135185 DOI: 10.1182/Bloodadvances.2016003616  0.32
2018 Mafi A, Abbina S, Kalathottukaren MT, Morrissey JH, Haynes C, Kizhakkedathu JN, Pfaendtner J, Chou KC. Design of Polyphosphate Inhibitors: a Molecular Dynamics Investigation on Polyethylene-glycol-linked Cationic Binding Groups. Biomacromolecules. PMID 29539260 DOI: 10.1021/Acs.Biomac.8B00327  0.323
2017 Kalathottukaren MT, Abbina S, Yu K, Shenoi RA, Creagh AL, Haynes C, Kizhakkedathu JN. A polymer therapeutic having universal heparin reversal activity: molecular design and functional mechanism. Biomacromolecules. PMID 28880550 DOI: 10.1021/Acs.Biomac.7B00994  0.357
2016 Vázquez-Villegas P, Ouellet E, González C, Ruiz-Ruiz F, Rito-Palomares M, Haynes CA, Aguilar O. A microdevice assisted approach for the preparation, characterization and selection of continuous aqueous two-phase systems: from micro to bench-scale. Lab On a Chip. PMID 27302418 DOI: 10.1039/C6Lc00333H  0.304
2016 Tauzin AS, Kwiatkowski KJ, Orlovsky NI, Smith CJ, Creagh AL, Haynes CA, Wawrzak Z, Brumer H, Koropatkin NM. Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont. Mbio. 7. PMID 27118585 DOI: 10.1128/Mbio.02134-15  0.351
2016 Yu K, Creagh AL, Haynes CA, Kizhakkedathu JN. Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry. Methods in Molecular Biology (Clifton, N.J.). 1367: 183-93. PMID 26537474 DOI: 10.1007/978-1-4939-3130-9_15  0.336
2015 Hughesman C, Fakhfakh K, Bidshahri R, Lund HL, Haynes C. A new general model for predicting melting thermodynamics of complementary and mismatched B-form duplexes containing locked nucleic acids: Application to probe design for digital PCR detection of somatic mutations Biochemistry. 54: 1338-1352. PMID 25654628 DOI: 10.1021/Bi500905B  0.316
2015 Ouellet E, Foley JH, Conway EM, Haynes C. Hi-Fi SELEX: A high-fidelity digital-PCR based therapeutic aptamer discovery platform Biotechnology and Bioengineering. 112: 1506-1522. DOI: 10.1002/Bit.25581  0.315
2014 Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN. Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants. Science Translational Medicine. 6: 260ra150. PMID 25355700 DOI: 10.1126/Scitranslmed.3009427  0.303
2014 Ouellet E, Lagally ET, Cheung KC, Haynes CA. A simple method for eliminating fixed-region interference of aptamer binding during SELEX. Biotechnology and Bioengineering. 111: 2265-79. PMID 24895227 DOI: 10.1002/Bit.25294  0.329
2014 Choy DYC, Creagh AL, Von Lieres E, Haynes C. A new mixed-mode model for interpreting and predicting protein elution during isoelectric chromatofocusing Biotechnology and Bioengineering. 111: 925-936. PMID 24293057 DOI: 10.1002/Bit.25166  0.352
2014 Choy DYC, Creagh AL, Haynes C. Improved isoelectric focusing chromatography on strong anion exchange media via a new model that custom designs mobile phases using simple buffers Biotechnology and Bioengineering. 111: 552-564. PMID 24166014 DOI: 10.1002/Bit.25122  0.31
2014 Koska J, Choy DYC, Francis P, Creagh AL, Haynes CA. Thermodynamic Modeling of Multi-Staged Extraction Systems for Chiral Separations through Coupled Analysis of Species Equilibria and Mass Transfer Separation Science and Technology (Philadelphia). 49: 635-646. DOI: 10.1080/01496395.2013.868489  0.306
2013 Yu K, Creagh AL, Haynes CA, Kizhakkedathu JN. Lectin interactions on surface-grafted glycostructures: influence of the spatial distribution of carbohydrates on the binding kinetics and rupture forces. Analytical Chemistry. 85: 7786-93. PMID 23931124 DOI: 10.1021/Ac401306B  0.332
2013 Ghosh P, Vahedipour K, Lin M, Vogel JH, Haynes CA, von Lieres E. Zonal rate model for axial and radial flow membrane chromatography. Part I: knowledge transfer across operating conditions and scales. Biotechnology and Bioengineering. 110: 1129-41. PMID 23097218 DOI: 10.1002/Bit.24771  0.327
2012 Francis P, Lieres Ev, Haynes C. Zonal rate model for stacked membrane chromatography part II: characterizing ion-exchange membrane chromatography under protein retention conditions. Biotechnology and Bioengineering. 109: 615-629. PMID 22012741 DOI: 10.1002/Bit.24349  0.356
2011 Francis P, von Lieres E, Haynes CA. Zonal rate model for stacked membrane chromatography. I: characterizing solute dispersion under flow-through conditions. Journal of Chromatography. A. 1218: 5071-8. PMID 21703630 DOI: 10.1016/J.Chroma.2011.05.017  0.302
2011 Hughesman CB, Turner RFB, Haynes CA. Role of the heat capacity change in understanding and modeling melting thermodynamics of complementary duplexes containing standard and nucleobase-modified LNA Biochemistry. 50: 5354-5368. PMID 21548576 DOI: 10.1021/Bi200223S  0.305
2010 Kizhakkedathu JN, Creagh AL, Shenoi RA, Rossi NA, Brooks DE, Chan T, Lam J, Dandepally SR, Haynes CA. High molecular weight polyglycerol-based multivalent mannose conjugates. Biomacromolecules. 11: 2567-75. PMID 20804173 DOI: 10.1021/Bm1004788  0.347
2009 Kavoosi M, Creagh AL, Turner RF, Kilburn DG, Haynes CA. Direct measurement of the kinetics of CBM9 fusion-tag bioprocessing using luminescence resonance energy transfer. Biotechnology Progress. 25: 874-81. PMID 19496182 DOI: 10.1002/Btpr.88  0.324
2009 Bordbar AK, Creagh AL, Mohammadi F, Haynes CA, Orvig C. Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin. Journal of Inorganic Biochemistry. 103: 643-7. PMID 19056126 DOI: 10.1016/J.Jinorgbio.2008.10.009  0.317
2008 Okon M, Moraes TF, Lario PI, Creagh AL, Haynes CA, Strynadka NC, McIntosh LP. Structural characterization of the type-III pilot-secretin complex from Shigella flexneri. Structure (London, England : 1993). 16: 1544-54. PMID 18940609 DOI: 10.1016/J.Str.2008.08.006  0.315
2008 Wilke MS, Heller M, Creagh AL, Haynes CA, McIntosh LP, Poole K, Strynadka NC. The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR. Proceedings of the National Academy of Sciences of the United States of America. 105: 14832-7. PMID 18812515 DOI: 10.1073/Pnas.0805489105  0.338
2007 Kavoosi M, Lam D, Bryan J, Kilburn DG, Haynes CA. Mechanically stable porous cellulose media for affinity purification of family 9 cellulose-binding module-tagged fusion proteins. Journal of Chromatography. A. 1175: 187-96. PMID 18023448 DOI: 10.1016/J.Chroma.2007.07.082  0.366
2007 Kavoosi M, Sanaie N, Dismer F, Hubbuch J, Kilburn DG, Haynes CA. A novel two-zone protein uptake model for affinity chromatography and its application to the description of elution band profiles of proteins fused to a family 9 cellulose binding module affinity tag. Journal of Chromatography. A. 1160: 137-49. PMID 17602694 DOI: 10.1016/J.Chroma.2007.05.107  0.372
2007 Clark AJ, Kotlicki A, Haynes CA, Whitehead LA. A new model of protein adsorption kinetics derived from simultaneous measurement of mass loading and changes in surface energy. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 5591-600. PMID 17425343 DOI: 10.1021/La0635350  0.332
2007 Kavoosi M, Creagh AL, Kilburn DG, Haynes CA. Strategy for selecting and characterizing linker peptides for CBM9-tagged fusion proteins expressed in Escherichia coli. Biotechnology and Bioengineering. 98: 599-610. PMID 17394253 DOI: 10.1002/Bit.21396  0.344
2007 Coad BR, Steels BM, Kizhakkedathu JN, Brooks DE, Haynes CA. The influence of grafted polymer architecture and fluid hydrodynamics on protein separation by entropic interaction chromatography. Biotechnology and Bioengineering. 97: 574-87. PMID 17154426 DOI: 10.1002/Bit.21283  0.318
2007 Sanaie N, Haynes CA. Modeling l‐dopa purification by chiral ligand‐exchange chromatography Aiche Journal. 53: 617-626. DOI: 10.1002/Aic.11111  0.328
2006 Sanaie N, Haynes CA. A multiple chemical equilibria approach to modeling and interpreting the separation of amino acid enantiomers by chiral ligand-exchange chromatography. Journal of Chromatography. A. 1132: 39-50. PMID 17002887 DOI: 10.1016/J.Chroma.2006.06.113  0.331
2006 Mazzola PG, Lam H, Kavoosi M, Haynes CA, Pessoa A, Penna TC, Wang DI, Blankschtein D. Affinity-tagged green fluorescent protein (GFP) extraction from a clarified E. coli cell lysate using a two-phase aqueous micellar system. Biotechnology and Bioengineering. 93: 998-1004. PMID 16470873 DOI: 10.1002/Bit.20806  0.349
2006 Sanaie N, Haynes CA. Interpreting the effects of temperature and solvent composition on separation of amino-acid racemates by chiral ligand-exchange chromatography. Journal of Chromatography. A. 1104: 164-72. PMID 16368103 DOI: 10.1016/J.Chroma.2005.11.111  0.321
2005 Lario PI, Pfuetzner RA, Frey EA, Creagh L, Haynes C, Maurelli AT, Strynadka NC. Structure and biochemical analysis of a secretin pilot protein. The Embo Journal. 24: 1111-21. PMID 15775974 DOI: 10.1038/Sj.Emboj.7600610  0.323
2005 Liu SM, Haynes CA. Energy landscapes for adsorption of a protein-like HP chain as a function of native-state stability. Journal of Colloid and Interface Science. 284: 7-13. PMID 15752778 DOI: 10.1016/J.Jcis.2004.09.064  0.304
2005 Pang P, Koska J, Coad BR, Brooks DE, Haynes CA. Entropic interaction chromatography: separating proteins on the basis of size using end-grafted polymer brushes. Biotechnology and Bioengineering. 90: 1-13. PMID 15706591 DOI: 10.1002/Bit.20430  0.342
2005 Creagh AL, Tiong JW, Tian MM, Haynes CA, Jefferies WA. Calorimetric studies of melanotransferrin (p97) and its interaction with iron. The Journal of Biological Chemistry. 280: 15735-41. PMID 15705575 DOI: 10.1074/Jbc.M414650200  0.314
2005 Lam H, Kavoosi M, Haynes CA, Wang DI, Blankschtein D. Affinity-enhanced protein partitioning in decyl beta-D-glucopyranoside two-phase aqueous micellar systems. Biotechnology and Bioengineering. 89: 381-92. PMID 15643631 DOI: 10.1002/Bit.20300  0.372
2004 Rodriguez B, Kavoosi M, Koska J, Creagh AL, Kilburn DG, Haynes CA. Inexpensive and generic affinity purification of recombinant proteins using a family 2a CBM fusion tag. Biotechnology Progress. 20: 1479-89. PMID 15458333 DOI: 10.1021/Bp0341904  0.336
2004 Tsai M, Sampaleanu LM, Greene C, Creagh L, Haynes C, Howell PL. A duck delta1 crystallin double loop mutant provides insight into residues important for argininosuccinate lyase activity. Biochemistry. 43: 11672-82. PMID 15362851 DOI: 10.1021/Bi0489006  0.309
2004 Bekker EG, Creagh AL, Sanaie N, Yumoto F, Lau GH, Tanokura M, Haynes CA, Murphy ME. Specificity of the synergistic anion for iron binding by ferric binding protein from Neisseria gonorrhoeae. Biochemistry. 43: 9195-203. PMID 15248777 DOI: 10.1021/Bi036143Q  0.339
2004 Liu SM, Haynes CA. Mesoscopic analysis of conformational and entropic contributions to nonspecific adsorption of HP copolymer chains using dynamic Monte Carlo simulations. Journal of Colloid and Interface Science. 275: 458-69. PMID 15178274 DOI: 10.1016/J.Jcis.2004.02.075  0.3
2004 Kavoosi M, Meijer J, Kwan E, Creagh AL, Kilburn DG, Haynes CA. Inexpensive one-step purification of polypeptides expressed in Escherichia coli as fusions with the family 9 carbohydrate-binding module of xylanase 10A from T. maritima. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 807: 87-94. PMID 15177165 DOI: 10.1016/J.Jchromb.2004.03.031  0.357
2002 McLean BW, Boraston AB, Brouwer D, Sanaie N, Fyfe CA, Warren RA, Kilburn DG, Haynes CA. Carbohydrate-binding modules recognize fine substructures of cellulose. The Journal of Biological Chemistry. 277: 50245-54. PMID 12191997 DOI: 10.1074/Jbc.M204433200  0.358
2002 Vogel JH, Anspach B, Kroner KH, Piret JM, Haynes CA. Controlled shear affinity filtration (CSAF): a new technology for integration of cell separation and protein isolation from mammalian cell cultures. Biotechnology and Bioengineering. 78: 806-14. PMID 12001173 DOI: 10.1002/Bit.10262  0.303
2001 Luo Y, Bertero MG, Frey EA, Pfuetzner RA, Wenk MR, Creagh L, Marcus SL, Lim D, Sicheri F, Kay C, Haynes C, Finlay BB, Strynadka NC. Structural and biochemical characterization of the type III secretion chaperones CesT and SigE. Nature Structural Biology. 8: 1031-6. PMID 11685226 DOI: 10.1038/Nsb717  0.326
2001 Koska J, Haynes CA. Modelling multiple chemical equilbria in chiral partition systems Chemical Engineering Science. 56: 5853-5864. DOI: 10.1016/S0009-2509(00)00419-X  0.307
2001 Koska J, Mui C, Haynes CA. Solvent effects in chiral ligand exchange systems Chemical Engineering Science. 56: 29-41. DOI: 10.1016/S0009-2509(00)00418-8  0.307
2000 McLean BW, Bray MR, Boraston AB, Gilkes NR, Haynes CA, Kilburn DG. Analysis of binding of the family 2a carbohydrate-binding module from Cellulomonas fimi xylanase 10A to cellulose: specificity and identification of functionally important amino acid residues. Protein Engineering. 13: 801-9. PMID 11161112 DOI: 10.1093/Protein/13.11.801  0.342
2000 Kormos J, Johnson PE, Brun E, Tomme P, McIntosh LP, Haynes CA, Kilburn DG. Binding site analysis of cellulose binding domain CBD(N1) from endoglucanse C of Cellulomonas fimi by site-directed mutagenesis. Biochemistry. 39: 8844-52. PMID 10913296 DOI: 10.1021/Bi000607S  0.327
2000 Brooks DE, Haynes CA, Hritcu D, Steels BM, Müller W. Size exclusion chromatography does not require pores Proceedings of the National Academy of Sciences of the United States of America. 97: 7064-7067. PMID 10852951 DOI: 10.1073/Pnas.120129097  0.326
1998 Tomme P, Boraston A, McLean B, Kormos J, Creagh AL, Sturch K, Gilkes NR, Haynes CA, Warren RA, Kilburn DG. Characterization and affinity applications of cellulose-binding domains. Journal of Chromatography. B, Biomedical Sciences and Applications. 715: 283-96. PMID 9792516 DOI: 10.1016/S0378-4347(98)00053-X  0.382
1998 Creagh AL, Koska J, Johnson PE, Tomme P, Joshi MD, McIntosh LP, Kilburn DG, Haynes CA. Stability and oligosaccharide binding of the N1 cellulose-binding domain of Cellulomonas fimi endoglucanase CenC. Biochemistry. 37: 3529-37. PMID 9521674 DOI: 10.1021/Bi971983O  0.379
1997 Hasenwinkle D, Jervis E, Kops O, Liu C, Lesnicki G, Haynes CA, Kilburn DG. Very high-level production and export in Escherichia coli of a cellulose binding domain for use in a generic secretion-affinity fusion system. Biotechnology and Bioengineering. 55: 854-63. PMID 18636596 DOI: 10.1002/(Sici)1097-0290(19970920)55:6<854::Aid-Bit4>3.0.Co;2-F  0.332
1997 Jervis EJ, Haynes CA, Kilburn DG. Surface diffusion of cellulases and their isolated binding domains on cellulose. The Journal of Biological Chemistry. 272: 24016-23. PMID 9295354 DOI: 10.1074/Jbc.272.38.24016  0.323
1997 Nikolova PV, Creagh AL, Duff SJB, Haynes CA. Thermostability And Irreversible Activity Loss Of Exoglucanase/Xylanase Cex From Cellulomonas Fimi Biochemistry. 36: 1381-1388. PMID 9063886 DOI: 10.1021/Bi962367F  0.316
1996 Tomme P, Gilkes NR, Guarna MM, Haynes CA, Hasenwinkle D, Jervis E, Johnson P, McIntosh L, Warren RA, Kilburn DG. Cellulose-binding domains. Versatile affinity tags for inexpensive large-scale purification, concentration, and immobilization of fusion proteins. Annals of the New York Academy of Sciences. 799: 418-24. PMID 8958104 DOI: 10.1111/J.1749-6632.1996.Tb33235.X  0.33
1996 Creagh AL, Ong E, Jervis E, Kilburn DG, Haynes CA. Binding of the cellulose-binding domain of exoglucanase Cex from Cellulomonas fimi to insoluble microcrystalline cellulose is entropically driven. Proceedings of the National Academy of Sciences of the United States of America. 93: 12229-34. PMID 8901562 DOI: 10.1073/Pnas.93.22.12229  0.358
1995 Haynes CA, Sherwood CS, Turner RFB. Characterization of an oligonucleotide-binding fluorescent ligand for application in affinity purification of dsDNA. Biotechnology and Bioengineering. 48: 25-35. PMID 18623457 DOI: 10.1002/Bit.260480106  0.345
1995 Haynes CA, Norde W. Structures and Stabilities of Adsorbed Proteins Journal of Colloid and Interface Science. 169: 313-328. DOI: 10.1006/Jcis.1995.1039  0.302
1995 Norde W, Gonzalez FG, Haynes CA. Protein adsorption on polystyrene latex particles. Polymers For Advanced Technologies. 6: 518-525. DOI: 10.1002/Pat.1995.220060713  0.318
1994 Haynes CA, Norde W. Globular proteins at solid/liquid interfaces Colloids and Surfaces B: Biointerfaces. 2: 517-566. DOI: 10.1016/0927-7765(94)80066-9  0.306
1994 Haynes CA, Sliwinsky E, Norde W. Structural and electrostatic properties of globular proteins at a polystyrene-water interface Journal of Colloid and Interface Science. 164: 394-409. DOI: 10.1006/Jcis.1994.1182  0.338
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