Year |
Citation |
Score |
2021 |
Wu T, Zhu J, Strickland A, Ko KW, Sasaki Y, Dingwall CB, Yamada Y, Figley MD, Mao X, Neiner A, Bloom AJ, DiAntonio A, Milbrandt J. Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss. Cell Reports. 37: 109872. PMID 34686345 DOI: 10.1016/j.celrep.2021.109872 |
0.604 |
|
2021 |
DiAntonio A, Milbrandt J, Figley MD. The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems. Frontiers in Immunology. 12: 752898. PMID 34630431 DOI: 10.3389/fimmu.2021.752898 |
0.533 |
|
2021 |
Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, et al. SARM1 is a metabolic sensor activated by an increased NMN/NAD ratio to trigger axon degeneration. Neuron. PMID 33657413 DOI: 10.1016/j.neuron.2021.02.009 |
0.576 |
|
2021 |
Shen C, Vohra M, Zhang P, Mao X, Figley MD, Zhu J, Sasaki Y, Wu H, DiAntonio A, Milbrandt J. Multiple domain interfaces mediate SARM1 autoinhibition. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33468661 DOI: 10.1073/pnas.2023151118 |
0.566 |
|
2020 |
Figley MD, DiAntonio A. The SARM1 axon degeneration pathway: control of the NAD metabolome regulates axon survival in health and disease. Current Opinion in Neurobiology. 63: 59-66. PMID 32311648 DOI: 10.1016/j.conb.2020.02.012 |
0.563 |
|
2020 |
Sasaki Y, Engber TM, Hughes RO, Figley MD, Wu T, Bosanac T, Devraj R, Milbrandt J, Krauss R, DiAntonio A. cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons. Experimental Neurology. 113252. PMID 32087251 DOI: 10.1016/J.Expneurol.2020.113252 |
0.584 |
|
2015 |
Figley MD, Gitler AD. Neurodegeneration: A Leg Up on TDP-43. Current Biology : Cb. 25: R728-31. PMID 26294190 DOI: 10.1016/J.Cub.2015.06.064 |
0.607 |
|
2014 |
Figley MD, Bieri G, Kolaitis RM, Taylor JP, Gitler AD. Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8083-97. PMID 24920614 DOI: 10.1523/JNEUROSCI.0543-14.2014 |
0.574 |
|
2014 |
Figley MD, Thomas A, Gitler AD. Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis. Neurobiology of Aging. 35: 936.e1-4. PMID 24269018 DOI: 10.1016/J.Neurobiolaging.2013.09.024 |
0.564 |
|
2013 |
Figley MD, Gitler AD. Yeast genetic screen reveals novel therapeutic strategy for ALS. Rare Diseases (Austin, Tex.). 1: e24420. PMID 25002991 DOI: 10.4161/rdis.24420 |
0.666 |
|
2012 |
Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/Ng.2434 |
0.49 |
|
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