Jeffrey Milbrandt, MD, PhD - Publications

Genetics Washington University School of Medicine, St. Louis, MO, United States 
Axonal degeneration, peripheral neuropathy, Myelination, Schwann cell metabolism

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ko KW, Milbrandt J, DiAntonio A. SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration. The Journal of Cell Biology. 219. PMID 32609299 DOI: 10.1083/jcb.201912047  0.8
2020 Bramley JC, Yenkin AL, Zaydman MA, DiAntonio A, Milbrandt JD, Buchser WJ. Domain-centric database to uncover structure of minimally characterized viral genomes. Scientific Data. 7: 202. PMID 32587259 DOI: 10.1038/s41597-020-0536-1  0.8
2020 Lalli MA, Chen X, Langmade SJ, Fronick CC, Sawyer CS, Burcea LC, Fulton RS, Heinz M, Buchser WJ, Head RD, Mitra RD, Milbrandt J. Rapid and extraction-free detection of SARS-CoV-2 from saliva with colorimetric LAMP. Medrxiv : the Preprint Server For Health Sciences. PMID 32511508 DOI: 10.1101/2020.05.07.20093542  0.8
2020 Wang PL, Yim AKY, Kim KW, Avey D, Czepielewski RS, Colonna M, Milbrandt J, Randolph GJ. Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia. Nature Communications. 11: 2552. PMID 32439942 DOI: 10.1038/s41467-020-16355-w  0.56
2020 Mikulka CR, Dearborn JT, Benitez BA, Strickland A, Liu L, Milbrandt J, Sands MS. Cell-autonomous expression of the acid hydrolase galactocerebrosidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 32253319 DOI: 10.1073/pnas.1917675117  0.56
2020 Sasaki Y, Engber TM, Hughes RO, Figley MD, Wu T, Bosanac T, Devraj R, Milbrandt J, Krauss R, DiAntonio A. cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons. Experimental Neurology. 113252. PMID 32087251 DOI: 10.1016/j.expneurol.2020.113252  0.8
2019 Hackett AR, Strickland A, Milbrandt J. Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy. Glia. PMID 31758725 DOI: 10.1002/glia.23755  0.56
2019 Summers DW, Frey E, Walker LJ, Milbrandt J, DiAntonio A. DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration. Molecular Neurobiology. PMID 31696428 DOI: 10.1007/s12035-019-01796-2  0.8
2019 Geisler S, Doan RA, Cheng GC, Cetinkaya-Fisgin A, Huang SX, Höke A, Milbrandt J, DiAntonio A. Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program. Jci Insight. 4. PMID 31484833 DOI: 10.1172/jci.insight.129920  0.8
2019 Wan L, Essuman K, Anderson RG, Sasaki Y, Monteiro F, Chung EH, Osborne Nishimura E, DiAntonio A, Milbrandt J, Dangl JL, Nishimura MT. TIR domains of plant immune receptors are NAD-cleaving enzymes that promote cell death. Science (New York, N.Y.). 365: 799-803. PMID 31439793 DOI: 10.1126/science.aax1771  0.8
2019 Geisler S, Huang SX, Strickland A, Doan RA, Summers DW, Mao X, Park J, DiAntonio A, Milbrandt J. Gene therapy targeting SARM1 blocks pathological axon degeneration in mice. The Journal of Experimental Medicine. PMID 30642945 DOI: 10.1084/jem.20181040  0.8
2018 Karney-Grobe S, Russo A, Frey E, Milbrandt J, DiAntonio A. HSP90 is a chaperone for DLK and is required for axon injury signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30275300 DOI: 10.1073/pnas.1805351115  0.8
2018 Avey D, Sankararaman S, Yim AKY, Barve R, Milbrandt J, Mitra RD. Single-Cell RNA-Seq Uncovers a Robust Transcriptional Response to Morphine by Glia. Cell Reports. 24: 3619-3629.e4. PMID 30257220 DOI: 10.1016/j.celrep.2018.08.080  0.56
2018 Summers DW, Milbrandt J, DiAntonio A. Palmitoylation enables MAPK-dependent proteostasis of axon survival factors. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150401 DOI: 10.1073/pnas.1806933115  0.8
2018 Kim S, Maynard JC, Strickland A, Burlingame AL, Milbrandt J. Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN. Proceedings of the National Academy of Sciences of the United States of America. PMID 30012597 DOI: 10.1073/pnas.1805538115  0.56
2018 Sasaki Y, Hackett AR, Kim S, Strickland A, Milbrandt J. Dysregulation of NAD metabolism induces a Schwann cell dedifferentiation program. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29921717 DOI: 10.1523/JNEUROSCI.3304-17.2018  0.56
2018 Essuman K, Summers DW, Sasaki Y, Mao X, Yim AKY, DiAntonio A, Milbrandt J. TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes. Current Biology : Cb. PMID 29395922 DOI: 10.1016/j.cub.2017.12.024  0.8
2017 McGill BE, Barve RA, Maloney SE, Strickland A, Rensing N, Wang P, Wong M, Head R, Wozniak DF, Milbrandt J. Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29133437 DOI: 10.1523/JNEUROSCI.0936-17.2017  0.56
2017 Galindo R, Banks Greenberg M, Araki T, Sasaki Y, Mehta N, Milbrandt J, Holtzman DM. NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia. Annals of Clinical and Translational Neurology. 4: 722-738. PMID 29046881 DOI: 10.1002/acn3.450  0.56
2017 Beirowski B, Wong KM, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484008 DOI: 10.1073/pnas.1620761114  0.56
2017 Essuman K, Summers DW, Sasaki Y, Mao X, DiAntonio A, Milbrandt J. The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD(+) Cleavage Activity that Promotes Pathological Axonal Degeneration. Neuron. 93: 1334-1343.e5. PMID 28334607 DOI: 10.1016/j.neuron.2017.02.022  0.8
2017 Walker LJ, Summers DW, Sasaki Y, Brace EJ, Milbrandt J, DiAntonio A. MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2. Elife. 6. PMID 28095293 DOI: 10.7554/eLife.22540  0.8
2016 Gujar AD, Le S, Mao DD, Dadey DY, Turski A, Sasaki Y, Aum D, Luo J, Dahiya S, Yuan L, Rich KM, Milbrandt J, Hallahan DE, Yano H, Tran DD, et al. An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930300 DOI: 10.1073/pnas.1610921114  0.56
2016 Geisler S, Doan RA, Strickland A, Huang X, Milbrandt J, DiAntonio A. Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice. Brain : a Journal of Neurology. PMID 27797810 DOI: 10.1093/brain/aww251  0.8
2016 Sasaki Y, Nakagawa T, Mao X, DiAntonio A, Milbrandt J. NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD(+) depletion. Elife. 5. PMID 27735788 DOI: 10.7554/eLife.19749  0.8
2016 Summers DW, Gibson DA, DiAntonio A, Milbrandt J. SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27671644 DOI: 10.1073/pnas.1601506113  0.8
2016 Kim S, Maynard JC, Sasaki Y, Strickland A, Sherman DL, Brophy PJ, Burlingame AL, Milbrandt J. Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9633-9646. PMID 27629714 DOI: 10.1523/JNEUROSCI.1235-16.2016  0.64
2016 Musiek ES, Xiong DD, Patel T, Sasaki Y, Wang Y, Bauer AQ, Singh R, Finn SL, Culver JP, Milbrandt J, Holtzman DM. Nmnat1 protects neuronal function without altering phospho-tau pathology in a mouse model of tauopathy. Annals of Clinical and Translational Neurology. 3: 434-42. PMID 27547771 DOI: 10.1002/acn3.308  0.56
2016 Bhattacharya MR, Geisler S, Pittman SK, Doan RA, Weihl CC, Milbrandt J, DiAntonio A. TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4681-9. PMID 27122027 DOI: 10.1523/JNEUROSCI.2893-15.2016  0.64
2016 Gerdts J, Summers DW, Milbrandt J, DiAntonio A. Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism. Neuron. 89: 449-60. PMID 26844829 DOI: 10.1016/j.neuron.2015.12.023  0.64
2015 Goyal MS, Venkatesh S, Milbrandt J, Gordon JI, Raichle ME. Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development. Proceedings of the National Academy of Sciences of the United States of America. 112: 14105-14112. PMID 26578751 DOI: 10.1073/pnas.1511465112  0.64
2015 Sasaki Y, Margolin Z, Borgo B, Havranek JJ, Milbrandt J. Characterization of Leber's Congenital Amaurosis-associated NMNAT1 Mutants. The Journal of Biological Chemistry. PMID 26018082 DOI: 10.1074/jbc.M115.637850  0.64
2015 Gerdts J, Brace EJ, Sasaki Y, DiAntonio A, Milbrandt J. Neurobiology. SARM1 activation triggers axon degeneration locally via NAD⁺ destruction. Science (New York, N.Y.). 348: 453-7. PMID 25908823 DOI: 10.1126/science.1258366  0.64
2015 Frey E, Valakh V, Karney-Grobe S, Shi Y, Milbrandt J, DiAntonio A. An in vitro assay to study induction of the regenerative state in sensory neurons. Experimental Neurology. 263: 350-63. PMID 25447942 DOI: 10.1016/j.expneurol.2014.10.012  0.64
2014 Beirowski B, Babetto E, Golden JP, Chen YJ, Yang K, Gross RW, Patti GJ, Milbrandt J. Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance. Nature Neuroscience. 17: 1351-61. PMID 25195104 DOI: 10.1038/nn.3809  0.64
2014 Summers DW, DiAntonio A, Milbrandt J. Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9338-50. PMID 25009267 DOI: 10.1523/JNEUROSCI.0877-14.2014  0.64
2014 Dela Cruz JE, Sullivan DN, Varboncouer E, Milbrandt JC, Duong M, Burdette S, O'Keefe D, Scaife SL, Saleh KJ. Comparison of procedural sedation for the reduction of dislocated total hip arthroplasty. The Western Journal of Emergency Medicine. 15: 76-80. PMID 24696752 DOI: 10.5811/westjem.2013.7.15616  0.68
2014 Cottrell CE, Al-Kateb H, Bredemeyer AJ, Duncavage EJ, Spencer DH, Abel HJ, Lockwood CM, Hagemann IS, O'Guin SM, Burcea LC, Sawyer CS, Oschwald DM, Stratman JL, Sher DA, Johnson MR, ... ... Milbrandt J, et al. Validation of a next-generation sequencing assay for clinical molecular oncology. The Journal of Molecular Diagnostics : Jmd. 16: 89-105. PMID 24211365 DOI: 10.1016/j.jmoldx.2013.10.002  0.64
2013 Sharma MK, Phillips J, Agarwal S, Wiggins WS, Shrivastava S, Koul SB, Bhattacharjee M, Houchins CD, Kalakota RR, George B, Meyer RR, Spencer DH, Lockwood CM, Nguyen TT, Duncavage EJ, ... ... Milbrandt JD, et al. Clinical genomicist workstation. Amia Joint Summits On Translational Science Proceedings Amia Summit On Translational Science. 2013: 156-7. PMID 24303327  0.64
2013 Gerdts J, Summers DW, Sasaki Y, DiAntonio A, Milbrandt J. Sarm1-mediated axon degeneration requires both SAM and TIR interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13569-80. PMID 23946415 DOI: 10.1523/JNEUROSCI.1197-13.2013  0.64
2013 Babetto E, Beirowski B, Russler EV, Milbrandt J, DiAntonio A. The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Cell Reports. 3: 1422-9. PMID 23665224 DOI: 10.1016/j.celrep.2013.04.013  0.64
2013 Scott B, Sun CL, Mao X, Yu C, Vohra BP, Milbrandt J, Crowder CM. Role of oxygen consumption in hypoxia protection by translation factor depletion. The Journal of Experimental Biology. 216: 2283-92. PMID 23531825 DOI: 10.1242/jeb.082263  0.64
2013 Viader A, Sasaki Y, Kim S, Strickland A, Workman CS, Yang K, Gross RW, Milbrandt J. Aberrant Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy. Neuron. 77: 886-98. PMID 23473319 DOI: 10.1016/j.neuron.2013.01.012  0.64
2013 Chang LW, Viader A, Varghese N, Payton JE, Milbrandt J, Nagarajan R. An integrated approach to characterize transcription factor and microRNA regulatory networks involved in Schwann cell response to peripheral nerve injury. Bmc Genomics. 14: 84. PMID 23387820 DOI: 10.1186/1471-2164-14-84  0.64
2013 Zhu Y, Zhang L, Sasaki Y, Milbrandt J, Gidday JM. Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1. Investigative Ophthalmology & Visual Science. 54: 25-36. PMID 23211826 DOI: 10.1167/iovs.12-10861  0.64
2012 Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayum S, Russler EV, Cavalli V, Milbrandt J, DiAntonio A. SCG10 is a JNK target in the axonal degeneration pathway. Proceedings of the National Academy of Sciences of the United States of America. 109: E3696-705. PMID 23188802 DOI: 10.1073/pnas.1216204109  0.64
2012 Ito TE, Hasnie R, Crosby DL, Milbrandt JC, Ettema S, Duong M. Gastric volvulus complication in an infant with undiagnosed congenital diaphragmatic hernia presenting with acute respiratory distress. Pediatric Emergency Care. 28: 1078-80. PMID 23034498 DOI: 10.1097/PEC.0b013e31826cedaf  0.68
2012 Patel A, Harker N, Moreira-Santos L, Ferreira M, Alden K, Timmis J, Foster K, Garefalaki A, Pachnis P, Andrews P, Enomoto H, Milbrandt J, Pachnis V, Coles MC, Kioussis D, et al. Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Science Signaling. 5: ra55. PMID 22855506 DOI: 10.1126/scisignal.2002734  0.64
2012 Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V, DiAntonio A. Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron. 74: 1015-22. PMID 22726832 DOI: 10.1016/j.neuron.2012.04.028  0.64
2012 Dasgupta B, Ju JS, Sasaki Y, Liu X, Jung SR, Higashida K, Lindquist D, Milbrandt J. The AMPK β2 subunit is required for energy homeostasis during metabolic stress. Molecular and Cellular Biology. 32: 2837-48. PMID 22586267 DOI: 10.1128/MCB.05853-11  0.64
2012 Bhattacharya MR, Gerdts J, Naylor SA, Royse EX, Ebstein SY, Sasaki Y, Milbrandt J, DiAntonio A. A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5054-61. PMID 22496551 DOI: 10.1523/JNEUROSCI.4951-11.2012  0.64
2012 Misko AL, Sasaki Y, Tuck E, Milbrandt J, Baloh RH. Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4145-55. PMID 22442078 DOI: 10.1523/JNEUROSCI.6338-11.2012  0.64
2012 Griffen D, Callahan CD, Markwell S, de la Cruz J, Milbrandt JC, Harvey T. Application of statistical process control to physician-specific emergency department patient satisfaction scores: a novel use of the funnel plot. Academic Emergency Medicine : Official Journal of the Society For Academic Emergency Medicine. 19: 348-55. PMID 22435869 DOI: 10.1111/j.1553-2712.2012.01304.x  0.68
2012 Zhang Y, Bekku Y, Dzhashiashvili Y, Armenti S, Meng X, Sasaki Y, Milbrandt J, Salzer JL. Assembly and maintenance of nodes of ranvier rely on distinct sources of proteins and targeting mechanisms. Neuron. 73: 92-107. PMID 22243749 DOI: 10.1016/j.neuron.2011.10.016  0.64
2011 Viader A, Chang LW, Fahrner T, Nagarajan R, Milbrandt J. MicroRNAs modulate Schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17358-69. PMID 22131398 DOI: 10.1523/JNEUROSCI.3931-11.2011  0.64
2011 Viader A, Wright-Jin EC, Vohra BP, Heuckeroth RO, Milbrandt J. Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction. Plos One. 6: e27727. PMID 22110743 DOI: 10.1371/journal.pone.0027727  0.64
2011 Dyrstad BW, Pope D, Milbrandt JC, Beck RT, Weinhoeft AL, Idusuyi OB. Predictive measures of a resident's performance on written Orthopaedic Board scores. The Iowa Orthopaedic Journal. 31: 238-43. PMID 22096449  0.68
2011 Verghese PB, Sasaki Y, Yang D, Stewart F, Sabar F, Finn MB, Wroge CM, Mennerick S, Neil JJ, Milbrandt J, Holtzman DM. Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death. Proceedings of the National Academy of Sciences of the United States of America. 108: 19054-9. PMID 22058226 DOI: 10.1073/pnas.1107325108  0.64
2011 Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J. Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: E952-61. PMID 21949390 DOI: 10.1073/pnas.1104969108  0.64
2011 Viader A, Golden JP, Baloh RH, Schmidt RE, Hunter DA, Milbrandt J. Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10128-40. PMID 21752989 DOI: 10.1523/JNEUROSCI.0884-11.2011  0.64
2011 Froelich JM, Milbrandt JC, Novicoff WM, Saleh KJ, Allan DG. Surgical simulators and hip fractures: A role in residency training? Journal of Surgical Education. 68: 298-302. PMID 21708367 DOI: 10.1016/j.jsurg.2011.02.011  0.68
2011 Gerdts J, Sasaki Y, Vohra B, Marasa J, Milbrandt J. Image-based screening identifies novel roles for IkappaB kinase and glycogen synthase kinase 3 in axonal degeneration. The Journal of Biological Chemistry. 286: 28011-8. PMID 21685387 DOI: 10.1074/jbc.M111.250472  0.64
2011 Rylander LS, Milbrandt JC, Wallace AB, Allan DG. Radiographic Evaluation of Midterm Failure Rates Following Metal-on-Metal Hip Resurfacing Journal of Arthroplasty. 26: 897-902. PMID 21131164 DOI: 10.1016/j.arth.2010.09.001  0.68
2010 Chang J, Zhang B, Heath H, Galjart N, Wang X, Milbrandt J. Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus. Proceedings of the National Academy of Sciences of the United States of America. 107: 21836-41. PMID 21106760 DOI: 10.1073/pnas.1002130107  0.64
2010 Sasaki Y, Milbrandt J. Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons. The Journal of Biological Chemistry. 285: 41211-5. PMID 21071441 DOI: 10.1074/jbc.C110.193904  0.64
2010 Keene R, Froelich JM, Milbrandt JC, Idusuyi OB. Bilateral gluteal compartment syndrome following robotic-assisted prostatectomy Orthopedics. 33. PMID 21053878 DOI: 10.3928/01477447-20100924-25  0.68
2010 Rylander LS, Milbrandt JC, Armington E, Wilson M, Olysav DJ. Trace metal analysis following locked volar plating for unstable fractures of the distal radius. The Iowa Orthopaedic Journal. 30: 89-93. PMID 21045978  0.68
2010 Vohra BP, Sasaki Y, Miller BR, Chang J, DiAntonio A, Milbrandt J. Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13729-38. PMID 20943913 DOI: 10.1523/JNEUROSCI.2939-10.2010  0.64
2010 Froelich J, Idusuyi OB, Clark D, Kogler GF, Paliwal M, Dyrstad B, Milbrandt JC. Torsional stiffness of an intramedullary nail versus blade plate fixation for tibiotalocalcaneal arthrodesis: a biomechanical study. Journal of Surgical Orthopaedic Advances. 19: 109-113. PMID 20727307  0.68
2010 Sams JD, Milbrandt JC, Froelich JM, Rainville AD, Allan DG. Hospital Outcome After Emergent vs Elective Revision Total Hip Arthroplasty Journal of Arthroplasty. 25: 826-828. PMID 20378305 DOI: 10.1016/j.arth.2010.01.097  0.68
2010 Sidorova YA, Mätlik K, Paveliev M, Lindahl M, Piranen E, Milbrandt J, Arumäe U, Saarma M, Bespalov MM. Persephin signaling through GFRalpha1: the potential for the treatment of Parkinson's disease. Molecular and Cellular Neurosciences. 44: 223-32. PMID 20350599 DOI: 10.1016/j.mcn.2010.03.009  0.64
2010 Misko A, Jiang S, Wegorzewska I, Milbrandt J, Baloh RH. Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4232-40. PMID 20335458 DOI: 10.1523/JNEUROSCI.6248-09.2010  0.64
2010 Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RW, Johnson EM, Jain S. RET signaling is required for survival and normal function of nonpeptidergic nociceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3983-94. PMID 20237269 DOI: 10.1523/JNEUROSCI.5930-09.2010  0.64
2010 Jain S, Knoten A, Hoshi M, Wang H, Vohra B, Heuckeroth RO, Milbrandt J. Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice. The Journal of Clinical Investigation. 120: 778-90. PMID 20160347 DOI: 10.1172/JCI41619  0.64
2010 Kaneda MM, Sasaki Y, Lanza GM, Milbrandt J, Wickline SA. Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions. Biomaterials. 31: 3079-86. PMID 20092889 DOI: 10.1016/j.biomaterials.2010.01.006  0.64
2009 Luo W, Enomoto H, Rice FL, Milbrandt J, Ginty DD. Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling. Neuron. 64: 841-56. PMID 20064391 DOI: 10.1016/j.neuron.2009.11.003  0.64
2009 Kopec M, Milbrandt JC, Kohut N, Kern B, Allan DG. Effect of bone cement viscosity and set time on mantle area in total knee arthroplasty. American Journal of Orthopedics (Belle Mead, N.J.). 38: 519-522. PMID 20011741  0.68
2009 Kopec M, Milbrandt JC, Duellman T, Mangan D, Allan DG. Effect of hand packing versus cement gun pressurization on cement mantle in total knee arthroplasty Canadian Journal of Surgery. 52: 490-494. PMID 20011185  0.68
2009 Mai MC, Milbrandt JC, Hulsen J, Allan DG. Acetabular cup malalignment after total hip resurfacing arthroplasty: A case for elective revision? Orthopedics. 32. PMID 19902880 DOI: 10.3928/01477447-20090922-22  0.68
2009 Bhattacharyya S, Wei J, Melichian DS, Milbrandt J, Takehara K, Varga J. The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma. Plos One. 4: e7620. PMID 19888474 DOI: 10.1371/journal.pone.0007620  0.64
2009 Harris D, Dyrstad B, Eltrevoog H, Milbrandt JC, Allan DG. Are honors received during surgery clerkships useful in the selection of incoming orthopaedic residents? The Iowa Orthopaedic Journal. 29: 88-90. PMID 19742092  0.68
2009 Kopec MA, Pemberton A, Milbrandt JC, Allan G. Component version in modular total hip revision. The Iowa Orthopaedic Journal. 29: 5-10. PMID 19742077  0.68
2009 Canty AJ, Dietze J, Harvey M, Enomoto H, Milbrandt J, Ibáñez CF. Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10695-705. PMID 19710321 DOI: 10.1523/JNEUROSCI.2658-09.2009  0.64
2009 Song H, Zhang B, Watson MA, Humphrey PA, Lim H, Milbrandt J. Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis. Oncogene. 28: 3307-19. PMID 19597465 DOI: 10.1038/onc.2009.181  0.64
2009 Chang J, Baloh RH, Milbrandt J. The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. Journal of Cell Science. 122: 2274-82. PMID 19509051 DOI: 10.1242/jcs.048975  0.64
2009 Froelich J, Milbrandt JC, Allan DG. Impact of the 80-hour Workweek on Surgical Exposure and National In-Training Examination Scores in an Orthopedic Residency Program Journal of Surgical Education. 66: 85-88. PMID 19486871 DOI: 10.1016/j.jsurg.2008.12.007  0.68
2009 Sasaki Y, Vohra BP, Baloh RH, Milbrandt J. Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6526-34. PMID 19458223 DOI: 10.1523/JNEUROSCI.1429-09.2009  0.64
2009 Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, Jain S, Kulkarni S, Shashikant K, Deardorff MA, Uzielli ML, Dorsett D, Beebe DC, Jay PY, Heuckeroth RO, ... ... Milbrandt J, et al. Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. Plos One. 4: e5232. PMID 19412548 DOI: 10.1371/journal.pone.0005232  0.64
2009 Sasaki Y, Vohra BP, Lund FE, Milbrandt J. Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5525-35. PMID 19403820 DOI: 10.1523/JNEUROSCI.5469-08.2009  0.64
2009 Duellman TJ, Gaffigan C, Milbrandt JC, Allan DG. Multi-modal, pre-emptive analgesia decreases the length of hospital stay following total joint arthroplasty Orthopedics. 32: 167. PMID 19309064  0.68
2009 Miller BR, Press C, Daniels RW, Sasaki Y, Milbrandt J, DiAntonio A. A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration. Nature Neuroscience. 12: 387-9. PMID 19287387 DOI: 10.1038/nn.2290  0.64
2009 Press C, Milbrandt J. The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro. Journal of Neurochemistry. 109: 595-602. PMID 19245660 DOI: 10.1111/j.1471-4159.2009.06002.x  0.64
2009 Baloh RH, Strickland A, Ryu E, Le N, Fahrner T, Yang M, Nagarajan R, Milbrandt J. Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2312-21. PMID 19244508 DOI: 10.1523/JNEUROSCI.2168-08.2009  0.64
2009 Dasgupta B, Milbrandt J. AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Developmental Cell. 16: 256-70. PMID 19217427 DOI: 10.1016/j.devcel.2009.01.005  0.64
2008 Braun RM, Bertino RE, Milbrandt J, Bray M. Ultrasound imaging of carotid artery stenosis: Application of the society of radiologists in ultrasound consensus criteria to a single institution clinical practice Ultrasound Quarterly. 24: 161-166. PMID 18776789 DOI: 10.1097/RUQ.0b013e31818625b6  0.68
2008 Ryu EJ, Yang M, Gustin JA, Chang LW, Freimuth RR, Nagarajan R, Milbrandt J. Analysis of peripheral nerve expression profiles identifies a novel myelin glycoprotein, MP11. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7563-73. PMID 18650334 DOI: 10.1523/JNEUROSCI.1659-08.2008  0.64
2008 Encinas M, Rozen EJ, Dolcet X, Jain S, Comella JX, Milbrandt J, Johnson EM. Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death and Differentiation. 15: 1510-21. PMID 18497757 DOI: 10.1038/cdd.2008.76  0.64
2008 Chen Y, Stevens B, Chang J, Milbrandt J, Barres BA, Hell JW. NS21: re-defined and modified supplement B27 for neuronal cultures. Journal of Neuroscience Methods. 171: 239-47. PMID 18471889 DOI: 10.1016/j.jneumeth.2008.03.013  0.64
2008 Press C, Milbrandt J. Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4861-71. PMID 18463239 DOI: 10.1523/JNEUROSCI.0525-08.2008  0.64
2008 Brantley MA, Jain S, Barr EE, Johnson EM, Milbrandt J. Neurturin-mediated ret activation is required for retinal function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4123-35. PMID 18417692 DOI: 10.1523/JNEUROSCI.0249-08.2008  0.64
2008 Richardson TD, Pineda SJ, Strenge KB, Van Fleet TA, MacGregor M, Milbrandt JC, Espinosa JA, Freitag P. Serum titanium levels after instrumented spinal arthrodesis Spine. 33: 792-796. PMID 18379407 DOI: 10.1097/BRS.0b013e318169574d  0.68
2008 Gallitano-Mendel A, Wozniak DF, Pehek EA, Milbrandt J. Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1266-75. PMID 17637609 DOI: 10.1038/sj.npp.1301505  0.64
2007 Revollo JR, Körner A, Mills KF, Satoh A, Wang T, Garten A, Dasgupta B, Sasaki Y, Wolberger C, Townsend RR, Milbrandt J, Kiess W, Imai S. Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metabolism. 6: 363-75. PMID 17983582 DOI: 10.1016/j.cmet.2007.09.003  0.64
2007 Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J. Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11552-9. PMID 17959798 DOI: 10.1523/JNEUROSCI.5497-06.2007  0.64
2007 Gallitano-Mendel A, Izumi Y, Tokuda K, Zorumski CF, Howell MP, Muglia LJ, Wozniak DF, Milbrandt J. The immediate early gene early growth response gene 3 mediates adaptation to stress and novelty. Neuroscience. 148: 633-43. PMID 17692471 DOI: 10.1016/j.neuroscience.2007.05.050  0.64
2007 Gustin JA, Yang M, Johnson EM, Milbrandt J. Deciphering adaptor specificity in GFL-dependent RET-mediated proliferation and neurite outgrowth. Journal of Neurochemistry. 102: 1184-94. PMID 17663753 DOI: 10.1111/j.1471-4159.2007.04624.x  0.64
2007 Zhang B, Jain S, Song H, Fu M, Heuckeroth RO, Erlich JM, Jay PY, Milbrandt J. Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome. Development (Cambridge, England). 134: 3191-201. PMID 17652350 DOI: 10.1242/dev.005884  0.64
2007 Baloh RH, Salavaggione E, Milbrandt J, Pestronk A. Familial parkinsonism and ophthalmoplegia from a mutation in the mitochondrial DNA helicase twinkle. Archives of Neurology. 64: 998-1000. PMID 17620490 DOI: 10.1001/archneur.64.7.998  0.64
2007 Mullican SE, Zhang S, Konopleva M, Ruvolo V, Andreeff M, Milbrandt J, Conneely OM. Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia. Nature Medicine. 13: 730-5. PMID 17515897 DOI: 10.1038/nm1579  0.64
2007 Uesaka T, Jain S, Yonemura S, Uchiyama Y, Milbrandt J, Enomoto H. Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype. Development (Cambridge, England). 134: 2171-81. PMID 17507417 DOI: 10.1242/dev.001388  0.64
2007 Dasgupta B, Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proceedings of the National Academy of Sciences of the United States of America. 104: 7217-22. PMID 17438283 DOI: 10.1073/pnas.0610068104  0.64
2007 Lee KW, Cobb LJ, Paharkova-Vatchkova V, Liu B, Milbrandt J, Cohen P. Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3. Carcinogenesis. 28: 1653-8. PMID 17434920 DOI: 10.1093/carcin/bgm088  0.64
2007 Allan DG, Trammell R, Dyrstad B, Barnhart B, Milbrandt JC. Serum cobalt and chromium elevations following hip resurfacing with the Cormet 2000 device Journal of Surgical Orthopaedic Advances. 16: 12-18. PMID 17371641  0.68
2007 Pierchala BA, Tsui CC, Milbrandt J, Johnson EM. NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation. Journal of Neurochemistry. 100: 1169-76. PMID 17241133 DOI: 10.1111/j.1471-4159.2006.04292.x  0.64
2007 Baloh RH, Schmidt RE, Pestronk A, Milbrandt J. Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 422-30. PMID 17215403 DOI: 10.1523/JNEUROSCI.4798-06.2007  0.64
2006 Jain S, Golden JP, Wozniak D, Pehek E, Johnson EM, Milbrandt J. RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11230-8. PMID 17065462 DOI: 10.1523/JNEUROSCI.1876-06.2006  0.64
2006 Sasaki Y, Araki T, Milbrandt J. Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8484-91. PMID 16914673 DOI: 10.1523/JNEUROSCI.2320-06.2006  0.64
2006 Wang X, Baloh RH, Milbrandt J, Garcia KC. Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors. Structure (London, England : 1993). 14: 1083-92. PMID 16765900 DOI: 10.1016/j.str.2006.05.010  0.64
2006 Pierchala BA, Milbrandt J, Johnson EM. Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2777-87. PMID 16525057 DOI: 10.1523/JNEUROSCI.3420-05.2006  0.64
2006 Jain S, Encinas M, Johnson EM, Milbrandt J. Critical and distinct roles for key RET tyrosine docking sites in renal development. Genes & Development. 20: 321-33. PMID 16452504 DOI: 10.1101/gad.1387206  0.64
2006 Chang LW, Nagarajan R, Magee JA, Milbrandt J, Stormo GD. A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles. Genome Research. 16: 405-13. PMID 16449500 DOI: 10.1101/gr.4303406  0.64
2006 Sarateanu CS, Retuerto MA, Beckmann JT, McGregor L, Carbray J, Patejunas G, Nayak L, Milbrandt J, Rosengart TK. An Egr-1 master switch for arteriogenesis: studies in Egr-1 homozygous negative and wild-type animals. The Journal of Thoracic and Cardiovascular Surgery. 131: 138-45. PMID 16399305 DOI: 10.1016/j.jtcvs.2005.08.052  0.64
2006 Bermingham JR, Shearin H, Pennington J, O'Moore J, Jaegle M, Driegen S, van Zon A, Darbas A, Ozkaynak E, Ryu EJ, Milbrandt J, Meijer D. The claw paw mutation reveals a role for Lgi4 in peripheral nerve development. Nature Neuroscience. 9: 76-84. PMID 16341215 DOI: 10.1038/nn1598  0.64
2006 Naughton CK, Jain S, Strickland AM, Gupta A, Milbrandt J. Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate. Biology of Reproduction. 74: 314-21. PMID 16237148 DOI: 10.1095/biolreprod.105.047365  0.64
2006 Magee JA, Chang LW, Stormo GD, Milbrandt J. Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element. Endocrinology. 147: 590-8. PMID 16210365 DOI: 10.1210/en.2005-1001  0.64
2005 Le N, Nagarajan R, Wang JY, Svaren J, LaPash C, Araki T, Schmidt RE, Milbrandt J. Nab proteins are essential for peripheral nervous system myelination. Nature Neuroscience. 8: 932-40. PMID 16136673 DOI: 10.1038/nn1490  0.64
2005 Kim SJ, Qu Z, Milbrandt J, Zhuo M. A transcription factor for cold sensation! Molecular Pain. 1: 11. PMID 15813958 DOI: 10.1186/1744-8069-1-11  0.64
2005 Le N, Nagarajan R, Wang JY, Araki T, Schmidt RE, Milbrandt J. Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination. Proceedings of the National Academy of Sciences of the United States of America. 102: 2596-601. PMID 15695336 DOI: 10.1073/pnas.0407836102  0.64
2005 Skinner MA, Kalyanaraman S, Safford SD, Heuckeroth RO, Tourtellotte W, Goyeau D, Goodfellow P, Milbrandt JD, Freemerman A. A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-deficient mice. The American Journal of Pathology. 166: 265-74. PMID 15632018 DOI: 10.1016/S0002-9440(10)62250-X  0.64
2005 Leitner ML, Wang LH, Osborne PA, Golden JP, Milbrandt J, Johnson EM. Expression and function of GDNF family ligands and receptors in the carotid body. Experimental Neurology. 191: S68-79. PMID 15629763 DOI: 10.1016/j.expneurol.2004.08.013  0.64
2005 Ko SW, Vadakkan KI, Ao H, Gallitano-Mendel A, Wei F, Milbrandt J, Zhuo M. Selective contribution of Egr1 (zif/268) to persistent inflammatory pain. The Journal of Pain : Official Journal of the American Pain Society. 6: 12-20. PMID 15629414 DOI: 10.1016/j.jpain.2004.10.001  0.64
2004 Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J. GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 44: 623-36. PMID 15541311 DOI: 10.1016/j.neuron.2004.10.032  0.64
2004 Jain S, Naughton CK, Yang M, Strickland A, Vij K, Encinas M, Golden J, Gupta A, Heuckeroth R, Johnson EM, Milbrandt J. Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis. Development (Cambridge, England). 131: 5503-13. PMID 15469971 DOI: 10.1242/dev.01421  0.64
2004 Schalch P, Patejunas G, Retuerto M, Sarateanu S, Milbrandt J, Thakker G, Kim D, Carbray J, Crystal RG, Rosengart TK. Homozygous deletion of early growth response 1 gene and critical limb ischemia after vascular ligation in mice: evidence for a central role in vascular homeostasis. The Journal of Thoracic and Cardiovascular Surgery. 128: 595-601. PMID 15457161 DOI: 10.1016/j.jtcvs.2004.02.036  0.64
2004 Araki T, Sasaki Y, Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science (New York, N.Y.). 305: 1010-3. PMID 15310905 DOI: 10.1126/science.1098014  0.64
2004 Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, Noble PW, Yehualaeshet T, Lu B, Flavell RA, Milbrandt J, Homer RJ, Elias JA. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. The Journal of Experimental Medicine. 200: 377-89. PMID 15289506 DOI: 10.1084/jem.20040104  0.64
2004 Crowder RJ, Enomoto H, Yang M, Johnson EM, Milbrandt J. Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth. The Journal of Biological Chemistry. 279: 42072-81. PMID 15286081 DOI: 10.1074/jbc.M403726200  0.64
2004 Yan H, Bergner AJ, Enomoto H, Milbrandt J, Newgreen DF, Young HM. Neural cells in the esophagus respond to glial cell line-derived neurotrophic factor and neurturin, and are RET-dependent. Developmental Biology. 272: 118-33. PMID 15242795 DOI: 10.1016/j.ydbio.2004.04.025  0.64
2004 Young HM, Bergner AJ, Anderson RB, Enomoto H, Milbrandt J, Newgreen DF, Whitington PM. Dynamics of neural crest-derived cell migration in the embryonic mouse gut. Developmental Biology. 270: 455-73. PMID 15183726 DOI: 10.1016/j.ydbio.2004.03.015  0.64
2004 Jain S, Watson MA, DeBenedetti MK, Hiraki Y, Moley JF, Milbrandt J. Expression profiles provide insights into early malignant potential and skeletal abnormalities in multiple endocrine neoplasia type 2B syndrome tumors. Cancer Research. 64: 3907-13. PMID 15173001 DOI: 10.1158/0008-5472.CAN-03-3801  0.64
2004 Wanigasekara Y, Airaksinen MS, Heuckeroth RO, Milbrandt J, Keast JR. Neurturin signalling via GFRα2 is essential for innervation of glandular but not muscle targets of sacral parasympathetic ganglion neurons Molecular and Cellular Neuroscience. 25: 288-300. PMID 15019945 DOI: 10.1016/j.mcn.2003.10.019  0.64
2004 Encinas M, Crowder RJ, Milbrandt J, Johnson EM. Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. The Journal of Biological Chemistry. 279: 18262-9. PMID 14766744 DOI: 10.1074/jbc.M400505200  0.64
2004 Ethier I, Beaudry G, St-Hilaire M, Milbrandt J, Rouillard C, Lévesque D. The transcription factor NGFI-B (Nur77) and retinoids play a critical role in acute neuroleptic-induced extrapyramidal effect and striatal neuropeptide gene expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 335-46. PMID 14603264 DOI: 10.1038/sj.npp.1300318  0.64
2003 Wilson RK, Ley TJ, Cole FS, Milbrandt JD, Clifton S, Fulton L, Fewell G, Minx P, Sun H, McLellan M, Pohl C, Mardis ER. Mutational profiling in the human genome. Cold Spring Harbor Symposia On Quantitative Biology. 68: 23-9. PMID 15338599 DOI: 10.1101/sqb.2003.68.23  0.64
2003 Golden JP, Milbrandt J, Johnson EM. Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. Experimental Neurology. 184: 447-55. PMID 14637114 DOI: 10.1016/j.expneurol.2003.07.999  0.64
2003 Ley TJ, Minx PJ, Walter MJ, Ries RE, Sun H, McLellan M, DiPersio JF, Link DC, Tomasson MH, Graubert TA, McLeod H, Khoury H, Watson M, Shannon W, Trinkaus K, ... ... Milbrandt JD, et al. A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14275-80. PMID 14614138 DOI: 10.1073/pnas.2335924100  0.64
2003 Araki T, Milbrandt J. ZNRF proteins constitute a family of presynaptic E3 ubiquitin ligases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9385-94. PMID 14561866  0.64
2003 Song XJ, Li DQ, Farley W, Luo LH, Heuckeroth RO, Milbrandt J, Pflugfelder SC. Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca. Investigative Ophthalmology & Visual Science. 44: 4223-9. PMID 14507865 DOI: 10.1167/iovs.02-1319  0.64
2003 Magee JA, Abdulkadir SA, Milbrandt J. Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation. Cancer Cell. 3: 273-83. PMID 12676585 DOI: 10.1016/S1535-6108(03)00047-3  0.64
2003 Graumlich JF, Blough LS, McLaughlin RG, Milbrandt JC, Calderon CL, Agha SA, Scheibel LW. Healing pressure ulcers with collagen or hydrocolloid: a randomized, controlled trial. Journal of the American Geriatrics Society. 51: 147-54. PMID 12558709 DOI: 10.1046/j.1532-5415.2003.51051.x  0.68
2003 Clements M, Duncan D, Milbrandt J. Drosophila NAB (dNAB) is an orphan transcriptional co-repressor required for correct CNS and eye development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 67-81. PMID 12508226 DOI: 10.1002/dvdy.10209  0.64
2002 Chen B, Knowles CH, Scott M, Anand P, Williams NS, Milbrandt J, Tam PKH. Idiopathic slow transit constipation and megacolon are not associated with neurturin mutations Neurogastroenterology and Motility. 14: 513-517. PMID 12358679 DOI: 10.1046/j.1365-2982.2002.00354.x  0.64
2002 Modur V, Nagarajan R, Evers BM, Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. The Journal of Biological Chemistry. 277: 47928-37. PMID 12351634 DOI: 10.1074/jbc.M207509200  0.64
2002 Bettini M, Xi H, Milbrandt J, Kersh GJ. Thymocyte development in early growth response gene 1-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 1713-20. PMID 12165491  0.64
2002 Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J. Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 35: 267-82. PMID 12160745 DOI: 10.1016/S0896-6273(02)00774-2  0.64
2002 Tsui-Pierchala BA, Encinas M, Milbrandt J, Johnson EM. Lipid rafts in neuronal signaling and function. Trends in Neurosciences. 25: 412-7. PMID 12127758 DOI: 10.1016/S0166-2236(02)02215-4  0.64
2002 Tsui-Pierchala BA, Ahrens RC, Crowder RJ, Milbrandt J, Johnson EM. The long and short isoforms of Ret function as independent signaling complexes. The Journal of Biological Chemistry. 277: 34618-25. PMID 12091387 DOI: 10.1074/jbc.M203580200  0.64
2002 Nagarajan R, Le N, Mahoney H, Araki T, Milbrandt J. Deciphering peripheral nerve myelination by using Schwann cell expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 99: 8998-9003. PMID 12084938 DOI: 10.1073/pnas.132080999  0.64
2002 Rakowicz WP, Staples CS, Milbrandt J, Brunstrom JE, Johnson EM. Glial cell line-derived neurotrophic factor promotes the survival of early postnatal spinal motor neurons in the lateral and medial motor columns in slice culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3953-62. PMID 12019314  0.64
2002 Abdulkadir SA, Magee JA, Peters TJ, Kaleem Z, Naughton CK, Humphrey PA, Milbrandt J. Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Molecular and Cellular Biology. 22: 1495-503. PMID 11839815  0.4
2002 Tsui-Pierchala BA, Milbrandt J, Johnson EM. NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons. Neuron. 33: 261-73. PMID 11804573 DOI: 10.1016/S0896-6273(01)00585-2  0.64
2000 Milbrandt JC, Holder TM, Wilson MC, Salvi RJ, Caspary DM. GAD levels and muscimol binding in rat inferior colliculus following acoustic trauma. Hearing Research. 147: 251-60. PMID 10962189 DOI: 10.1016/S0378-5955(00)00135-0  0.68
2000 Wang DZ, Rose JA, Honings DS, Garwacki DJ, Milbrandt JC. Treating acute stroke patients with intravenous tPA: The OSF Stroke Network experience Stroke. 31: 77-81. PMID 10625719 DOI: 10.1161/01.STR.31.1.77  0.68
1999 Caspary DM, Holder TM, Hughes LF, Milbrandt JC, McKernan RM, Naritoku DK. Age-related changes in GABA(A) receptor subunit composition and function in rat auditory system. Neuroscience. 93: 307-12. PMID 10430494 DOI: 10.1016/S0306-4522(99)00121-9  0.68
1999 Ryu JR, Jobe PC, Milbrandt JC, Mishra PK, Clough RW, Browning RA, Dailey JW, Seo DO, Ko KH. Morphological deficits in noradrenergic neurons in GEPR-9s stem from abnormalities in both the locus coeruleus and its target tissues. Experimental Neurology. 156: 84-91. PMID 10192779 DOI: 10.1006/exnr.1998.7003  0.68
1999 Nakayama M, Caspary DM, Konrad HR, Milbrandt JC, Helfert RH. Age-related changes in [3H]strychnine binding in the vestibular nuclei of rats. Hearing Research. 127: 103-7. PMID 9925021 DOI: 10.1016/S0378-5955(98)00177-4  0.68
1998 Dailey JW, Reith ME, Steidley KR, Milbrandt JC, Jobe PC. Carbamazepine-induced release of serotonin from rat hippocampus in vitro. Epilepsia. 39: 1054-63. PMID 9776325 DOI: 10.1111/j.1528-1157.1998.tb01290.x  0.68
1997 Willott JF, Milbrandt JC, Bross LS, Caspary DM. Glycine immunoreactivity and receptor binding in the cochlear nucleus of C57BL/6J and CBA/CaJ mice: effects of cochlear impairment and aging. The Journal of Comparative Neurology. 385: 405-14. PMID 9300767 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<405::AID-CNE5>3.0.CO;2-7  0.68
1997 Milbrandt JC, Hunter C, Caspary DM. Alterations of GABAA receptor subunit mRNA levels in the aging Fischer 344 rat inferior colliculus. The Journal of Comparative Neurology. 379: 455-65. PMID 9067836 DOI: 10.1002/(SICI)1096-9861(19970317)379:3<455::AID-CNE10>3.0.CO;2-F  0.68
1996 Milbrandt JC, Albin RL, Turgeon SM, Caspary DM. GABAA receptor binding in the aging rat inferior colliculus. Neuroscience. 73: 449-58. PMID 8783261 DOI: 10.1016/0306-4522(96)00050-4  0.68
1995 Milbrandt JC, Caspary DM. Age-related reduction of [3H]strychnine binding sites in the cochlear nucleus of the Fischer 344 rat. Neuroscience. 67: 713-9. PMID 7675197 DOI: 10.1016/0306-4522(95)00082-T  0.68
1995 Caspary DM, Milbrandt JC, Helfert RH. Central auditory aging: GABA changes in the inferior colliculus. Experimental Gerontology. 30: 349-60. PMID 7556513 DOI: 10.1016/0531-5565(94)00052-5  0.68
1994 Raza A, Milbrandt JC, Arneric SP, Caspary DM. Age-related changes in brainstem auditory neurotransmitters: measures of GABA and acetylcholine function. Hearing Research. 77: 221-30. PMID 7928735 DOI: 10.1016/0378-5955(94)90270-4  0.68
1994 Milbrandt JC, Albin RL, Caspary DM. Age-related decrease in GABAB receptor binding in the Fischer 344 rat inferior colliculus. Neurobiology of Aging. 15: 699-703. PMID 7891824 DOI: 10.1016/0197-4580(94)90051-5  0.68
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