Steven Finkbeiner - Publications

University of California, San Francisco, San Francisco, CA 
Molecular Mechanisms of Synaptic Plasticity and Neurodegeneration

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/JCI80339  0.52
2016 Zhang X, Abels ER, Redzic JS, Margulis J, Finkbeiner S, Breakefield XO. Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington's Disease: Background and Evaluation in Cell Culture. Cellular and Molecular Neurobiology. PMID 26951563 DOI: 10.1007/s10571-016-0350-7  0.52
2016 Shaby BA, Skibinski G, Ando M, LaDow ES, Finkbeiner S. A three-groups model for high-throughput survival screens. Biometrics. PMID 26821783 DOI: 10.1111/biom.12479  0.52
2016 Possin KL, Sanchez PE, Anderson-Bergman C, Fernandez R, Kerchner GA, Johnson ET, Davis A, Lo I, Bott NT, Kiely T, Fenesy MC, Miller BL, Kramer JH, Finkbeiner S. Cross-species translation of the Morris maze for Alzheimer's disease. The Journal of Clinical Investigation. PMID 26784542 DOI: 10.1172/JCI78464  0.52
2016 Haston KM, Finkbeiner S. Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases. Annual Review of Pharmacology and Toxicology. 56: 489-510. PMID 26514199 DOI: 10.1146/annurev-pharmtox-010715-103548  0.52
2015 Lee JM, Kim KH, Shin A, Chao MJ, Abu Elneel K, Gillis T, Mysore JS, Kaye JA, Zahed H, Kratter IH, Daub AC, Finkbeiner S, Li H, Roach JC, Goodman N, et al. Sequence-Level Analysis of the Major European Huntington Disease Haplotype. American Journal of Human Genetics. 97: 435-44. PMID 26320893 DOI: 10.1016/j.ajhg.2015.07.017  0.52
2015 Campioni MR, Finkbeiner S. Going retro: ancient viral origins of cognition. Neuron. 86: 346-8. PMID 25905805 DOI: 10.1016/j.neuron.2015.04.008  0.52
2015 Finkbeiner S, Frumkin M, Kassner PD. Cell-based screening: extracting meaning from complex data. Neuron. 86: 160-74. PMID 25856492 DOI: 10.1016/j.neuron.2015.02.023  0.52
2015 Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EMH, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-7826. DOI: 10.1073/pnas.1509744112  0.52
2014 Vieira FG, LaDow E, Moreno A, Kidd JD, Levine B, Thompson K, Gill A, Finkbeiner S, Perrin S. Dexpramipexole is ineffective in two models of ALS related neurodegeneration. Plos One. 9: e91608. PMID 25526593 DOI: 10.1371/journal.pone.0091608  0.52
2014 Ochaba J, Lukacsovich T, Csikos G, Zheng S, Margulis J, Salazar L, Mao K, Lau AL, Yeung SY, Humbert S, Saudou F, Klionsky DJ, Finkbeiner S, Zeitlin SO, Marsh JL, et al. Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: 16889-94. PMID 25385587 DOI: 10.1073/pnas.1420103111  0.52
2014 Mason AR, Ziemann A, Finkbeiner S. Targeting the low-hanging fruit of neurodegeneration. Neurology. 83: 1470-3. PMID 25313376 DOI: 10.1212/WNL.0000000000000894  0.52
2014 Sieber BA, Landis S, Koroshetz W, Bateman R, Siderowf A, Galpern WR, Dunlop J, Finkbeiner S, Sutherland M, Wang H, Lee VM, Orr HT, Gwinn K, Ludwig K, Taylor A, et al. Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference. Annals of Neurology. 76: 469-72. PMID 25164235 DOI: 10.1002/ana.24261  0.52
2014 Margulis J, Finkbeiner S. Proteostasis in striatal cells and selective neurodegeneration in Huntington's disease. Frontiers in Cellular Neuroscience. 8: 218. PMID 25147502 DOI: 10.3389/fncel.2014.00218  0.52
2014 Barmada SJ, Serio A, Arjun A, Bilican B, Daub A, Ando DM, Tsvetkov A, Pleiss M, Li X, Peisach D, Shaw C, Chandran S, Finkbeiner S. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models. Nature Chemical Biology. 10: 677-85. PMID 24974230 DOI: 10.1038/nchembio.1563  0.52
2014 Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, et al. Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. Plos One. 9: e87133. PMID 24551051 DOI: 10.1371/journal.pone.0087133  0.52
2014 Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 124: 981-99. PMID 24509083 DOI: 10.1172/JCI72723  0.52
2014 Skibinski G, Nakamura K, Cookson MR, Finkbeiner S. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 418-33. PMID 24403142 DOI: 10.1523/JNEUROSCI.2712-13.2014  0.52
2014 You SC, Geschwind MD, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess CP, Kramer JH, Possin KL. Executive functions in premanifest Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 405-9. PMID 24375511 DOI: 10.1002/mds.25762  0.52
2014 Kim HJ, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM, Finkbeiner S, Gitler AD, Bonini NM. Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Nature Genetics. 46: 152-60. PMID 24336168 DOI: 10.1038/ng.2853  0.52
2013 Korb E, Finkbeiner S. PML in the Brain: From Development to Degeneration. Frontiers in Oncology. 3: 242. PMID 24062991 DOI: 10.3389/fonc.2013.00242  0.52
2013 Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2: e00508. PMID 24040509 DOI: 10.7554/eLife.00508  0.52
2013 Finkbeiner S. Startups on the menu Nature Biotechnology. 31: 680. PMID 23929335  0.52
2013 Tsvetkov AS, Arrasate M, Barmada S, Ando DM, Sharma P, Shaby BA, Finkbeiner S. Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration. Nature Chemical Biology. 9: 586-92. PMID 23873212 DOI: 10.1038/nchembio.1308  0.52
2013 Vashishtha M, Ng CW, Yildirim F, Gipson TA, Kratter IH, Bodai L, Song W, Lau A, Labadorf A, Vogel-Ciernia A, Troncosco J, Ross CA, Bates GP, Krainc D, Sadri-Vakili G, ... Finkbeiner S, et al. Targeting H3K4 trimethylation in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E3027-36. PMID 23872847 DOI: 10.1073/pnas.1311323110  0.52
2013 Korb E, Wilkinson CL, Delgado RN, Lovero KL, Finkbeiner S. Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity. Nature Neuroscience. 16: 874-83. PMID 23749147 DOI: 10.1038/nn.3429  0.52
2013 Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Finkbeiner S, et al. Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2. PMID 23740897 DOI: 10.1126/scitranslmed.3005065  0.52
2013 Tsvetkov AS, Ando DM, Finkbeiner S. Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins. Methods in Molecular Biology (Clifton, N.J.). 1017: 1-20. PMID 23719904 DOI: 10.1007/978-1-62703-438-8_1  0.52
2013 Aron R, Tsvetkov A, Finkbeiner S. NUB1 snubs huntingtin toxicity. Nature Neuroscience. 16: 523-5. PMID 23619755 DOI: 10.1038/nn.3380  0.52
2013 Kaye JA, Finkbeiner S. Modeling Huntington's disease with induced pluripotent stem cells. Molecular and Cellular Neurosciences. 56: 50-64. PMID 23459227 DOI: 10.1016/j.mcn.2013.02.005  0.52
2013 Skibinski G, Finkbeiner S. Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease. Febs Letters. 587: 1139-46. PMID 23458259 DOI: 10.1016/j.febslet.2013.02.043  0.52
2013 Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, ... ... Finkbeiner S, et al. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 110: 4697-702. PMID 23401527 DOI: 10.1073/pnas.1300398110  0.52
2012 Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/ng.2434  0.52
2012 Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/JCI63113  0.52
2012 Wray S, Self M, Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, ... ... Finkbeiner S, et al. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. Plos One. 7: e43099. PMID 22952635 DOI: 10.1371/journal.pone.0043099  0.52
2012 Sontag EM, Lotz GP, Agrawal N, Tran A, Aron R, Yang G, Necula M, Lau A, Finkbeiner S, Glabe C, Marsh JL, Muchowski PJ, Thompson LM. Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11109-19. PMID 22875942 DOI: 10.1523/JNEUROSCI.0895-12.2012  0.52
2012 Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Finkbeiner S, et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8. PMID 22451909 DOI: 10.1073/pnas.1202922109  0.52
2012 Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein. The Journal of Biological Chemistry. 287: 16017-28. PMID 22433867 DOI: 10.1074/jbc.M111.252577  0.52
2012 Sharma P, Ando DM, Daub A, Kaye JA, Finkbeiner S. High-throughput screening in primary neurons. Methods in Enzymology. 506: 331-60. PMID 22341232 DOI: 10.1016/B978-0-12-391856-7.00041-X  0.52
2012 Peters-Libeu C, Miller J, Rutenber E, Newhouse Y, Krishnan P, Cheung K, Hatters D, Brooks E, Widjaja K, Tran T, Mitra S, Arrasate M, Mosquera LA, Taylor D, Weisgraber KH, ... Finkbeiner S, et al. Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. Journal of Molecular Biology. 421: 587-600. PMID 22306738 DOI: 10.1016/j.jmb.2012.01.034  0.52
2012 Arrasate M, Finkbeiner S. Protein aggregates in Huntington's disease. Experimental Neurology. 238: 1-11. PMID 22200539 DOI: 10.1016/j.expneurol.2011.12.013  0.52
2011 Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Finkbeiner S, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/nchembio.694  0.52
2011 Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, et al. A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 7: 1273-94. PMID 21997368 DOI: 10.4161/auto.7.11.17661  0.52
2011 Korb E, Finkbeiner S. Arc in synaptic plasticity: from gene to behavior. Trends in Neurosciences. 34: 591-8. PMID 21963089 DOI: 10.1016/j.tins.2011.08.007  0.52
2011 Gittis AH, Hang GB, LaDow ES, Shoenfeld LR, Atallah BV, Finkbeiner S, Kreitzer AC. Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. Neuron. 71: 858-68. PMID 21903079 DOI: 10.1016/j.neuron.2011.06.035  0.52
2011 Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, et al. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. The Journal of Biological Chemistry. 286: 20710-26. PMID 21489994 DOI: 10.1074/jbc.M110.213538  0.52
2011 Finkbeiner S. Huntington's Disease. Cold Spring Harbor Perspectives in Biology. 3. PMID 21441583 DOI: 10.1101/cshperspect.a007476  0.52
2011 Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. A compact beta model of huntingtin toxicity. The Journal of Biological Chemistry. 286: 8188-96. PMID 21209075 DOI: 10.1074/jbc.M110.192013  0.52
2010 Barmada SJ, Finkbeiner S. Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways. Reviews in the Neurosciences. 21: 251-72. PMID 21086759  0.52
2010 Finkbeiner S. Bridging the Valley of Death of therapeutics for neurodegeneration. Nature Medicine. 16: 1227-32. PMID 21052079 DOI: 10.1038/nm.2222  0.52
2010 Barmada S, Finkbeiner S. Bringing SOD1 into the fold. Nature Neuroscience. 13: 1303-4. PMID 20975748 DOI: 10.1038/nn1110-1303  0.52
2010 Peebles CL, Yoo J, Thwin MT, Palop JJ, Noebels JL, Finkbeiner S. Arc regulates spine morphology and maintains network stability in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 18173-8. PMID 20921410 DOI: 10.1073/pnas.1006546107  0.52
2010 Kratter IH, Finkbeiner S. PolyQ disease: too many Qs, too much function? Neuron. 67: 897-9. PMID 20869586 DOI: 10.1016/j.neuron.2010.09.012  0.52
2010 Tsvetkov AS, Miller J, Arrasate M, Wong JS, Pleiss MA, Finkbeiner S. A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model. Proceedings of the National Academy of Sciences of the United States of America. 107: 16982-7. PMID 20833817 DOI: 10.1073/pnas.1004498107  0.52
2010 Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, Finkbeiner S, Cui B, Mucke L. Tau reduction prevents Abeta-induced defects in axonal transport. Science (New York, N.Y.). 330: 198. PMID 20829454 DOI: 10.1126/science.1194653  0.52
2010 Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10541-50. PMID 20685997 DOI: 10.1523/JNEUROSCI.0146-10.2010  0.52
2010 Ramdzan YM, Nisbet RM, Miller J, Finkbeiner S, Hill AF, Hatters DM. Conformation sensors that distinguish monomeric proteins from oligomers in live cells. Chemistry & Biology. 17: 371-9. PMID 20416508 DOI: 10.1016/j.chembiol.2010.03.011  0.52
2010 Landles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP. Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. The Journal of Biological Chemistry. 285: 8808-23. PMID 20086007 DOI: 10.1074/jbc.M109.075028  0.52
2010 Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S. Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 639-49. PMID 20071528 DOI: 10.1523/JNEUROSCI.4988-09.2010  0.52
2010 Sathasivam K, Lane A, Legleiter J, Warley A, Woodman B, Finkbeiner S, Paganetti P, Muchowski PJ, Wilson S, Bates GP. Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease. Human Molecular Genetics. 19: 65-78. PMID 19825844 DOI: 10.1093/hmg/ddp467  0.52
2010 Tsvetkov AS, Finkbeiner S. Reply to Rubinsztein and Nixon: Potent and reliable autophagy induction in neurons Proceedings of the National Academy of Sciences of the United States of America. 107: E182. DOI: 10.1073/pnas.1014950107  0.52
2010 Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S. Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis (Journal of Neuroscience (2010) (639-649)) Journal of Neuroscience. 30.  0.52
2009 Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron. 64: 828-40. PMID 20064390 DOI: 10.1016/j.neuron.2009.11.020  0.52
2009 Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, ... ... Finkbeiner S, et al. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of Cell Biology. 187: 1083-99. PMID 20026656 DOI: 10.1083/jcb.200909067  0.52
2009 Daub A, Sharma P, Finkbeiner S. High-content screening of primary neurons: ready for prime time. Current Opinion in Neurobiology. 19: 537-43. PMID 19889533 DOI: 10.1016/j.conb.2009.10.002  0.52
2009 Mitra S, Tsvetkov AS, Finkbeiner S. Protein turnover and inclusion body formation. Autophagy. 5: 1037-8. PMID 19838079 DOI: 10.4161/auto.5.7.9291  0.52
2009 Legleiter J, Lotz GP, Miller J, Ko J, Ng C, Williams GL, Finkbeiner S, Patterson PH, Muchowski PJ. Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment. The Journal of Biological Chemistry. 284: 21647-58. PMID 19491400 DOI: 10.1074/jbc.M109.016923  0.52
2009 Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE. Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. Human Molecular Genetics. 18: 1937-50. PMID 19279159 DOI: 10.1093/hmg/ddp115  0.52
2009 Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1525-37. PMID 19193899 DOI: 10.1523/JNEUROSCI.5575-08.2009  0.52
2009 Mitra S, Tsvetkov AS, Finkbeiner S. Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease. The Journal of Biological Chemistry. 284: 4398-403. PMID 19074152 DOI: 10.1074/jbc.M806269200  0.52
2008 Finkbeiner S, Mitra S. The ubiquitin-proteasome pathway in Huntington's disease. Thescientificworldjournal. 8: 421-33. PMID 18454252 DOI: 10.1100/tsw.2008.60  0.52
2007 Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/j.neuron.2007.07.025  0.52
2007 Peebles CL, Finkbeiner S. RNA decay back in play. Nature Neuroscience. 10: 1083-4. PMID 17726472 DOI: 10.1038/nn0907-1083  0.52
2007 Rao VR, Finkbeiner S. NMDA and AMPA receptors: old channels, new tricks. Trends in Neurosciences. 30: 284-91. PMID 17418904 DOI: 10.1016/j.tins.2007.03.012  0.52
2006 Beal MF, Bossy-Wetzel E, Finkbeiner S, Fiskum G, Giasson B, Johnson C, Khachaturian ZS, Lee VM, Nicholls D, Reddy H, Reynolds I, Teplow DB, Thal LJ, Trojanowski JQ, Walsh DM, et al. Common threads in neurodegenerative disorders of aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 322-6. PMID 19595906 DOI: 10.1016/j.jalz.2006.08.008  0.52
2006 Finkbeiner S, Cuervo AM, Morimoto RI, Muchowski PJ. Disease-modifying pathways in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10349-57. PMID 17035516 DOI: 10.1523/JNEUROSCI.3829-06.2006  0.52
2006 Rao VR, Pintchovski SA, Chin J, Peebles CL, Mitra S, Finkbeiner S. AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc. Nature Neuroscience. 9: 887-95. PMID 16732277 DOI: 10.1038/nn1708  0.52
2006 Bradley J, Carter SR, Rao VR, Wang J, Finkbeiner S. Splice variants of the NR1 subunit differentially induce NMDA receptor-dependent gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1065-76. PMID 16436592 DOI: 10.1523/JNEUROSCI.3347-05.2006  0.52
2005 Peters-Libeu C, Newhouse Y, Krishnan P, Cheung K, Brooks E, Weisgraber K, Finkbeiner S. Crystallization and diffraction properties of the Fab fragment of 3B5H10, an antibody specific for disease-causing polyglutamine stretches. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 1065-8. PMID 16511236 DOI: 10.1107/S1744309105036547  0.52
2005 Arrasate M, Finkbeiner S. Automated microscope system for determining factors that predict neuronal fate. Proceedings of the National Academy of Sciences of the United States of America. 102: 3840-5. PMID 15738408 DOI: 10.1073/pnas.0409777102  0.52
2004 Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature. 431: 805-10. PMID 15483602 DOI: 10.1038/nature02998  0.52
2004 Brooks E, Arrasate M, Cheung K, Finkbeiner SM. Using antibodies to analyze polyglutamine stretches. Methods in Molecular Biology (Clifton, N.J.). 277: 103-28. PMID 15201452 DOI: 10.1385/1-59259-804-8:103  0.52
2003 Rao VR, Finkbeiner S. Secrets of a secretase: N-cadherin proteolysis regulates CBP function. Cell. 114: 533-5. PMID 13678577 DOI: 10.1016/S0092-8674(03)00686-X  0.52
2002 Bradley J, Finkbeiner S. An evaluation of specificity in activity-dependent gene expression in neurons. Progress in Neurobiology. 67: 469-77. PMID 12385865 DOI: 10.1016/S0301-0082(02)00047-3  0.52
2002 Humbert S, Bryson EA, Cordelières FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME, Saudou F. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Developmental Cell. 2: 831-7. PMID 12062094 DOI: 10.1016/S1534-5807(02)00188-0  0.52
2001 Finkbeiner S. New roles for introns: sites of combinatorial regulation of Ca2+- and cyclic AMP-dependent gene transcription Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001: PE1. PMID 11752669  0.52
2000 Finkbeiner S. Calcium regulation of the brain-derived neurotrophic factor gene Cellular and Molecular Life Sciences. 57: 394-401. PMID 10823240  0.52
2000 Finkbeiner S. CREB couples neurotrophin signals to survival messages Neuron. 25: 11-14. PMID 10707967  0.52
1999 Curtis J, Finkbeiner S. Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth Journal of Neuroscience Research. 58: 88-95. PMID 10491574 DOI: 10.1002/(SICI)1097-4547(19991001)58:1<88::AID-JNR9>3.0.CO;2-R  0.52
1998 Finkbeiner S, Dalva MB. To fear or not to fear: what was the question? A potential role for Ras-GRF in memory. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 691-5. PMID 9819557 DOI: 10.1002/(SICI)1521-1878(199809)20:9<691::AID-BIES1>3.0.CO;2-K  0.52
1998 Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95: 55-66. PMID 9778247 DOI: 10.1016/S0092-8674(00)81782-1  0.52
1998 Finkbeiner S, Greenberg ME. Ca2+ channel-regulated neuronal gene expression. Journal of Neurobiology. 37: 171-89. PMID 9777740 DOI: 10.1002/(SICI)1097-4695(199810)37:1<171::AID-NEU13>3.0.CO;2-H  0.52
1998 Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron. 20: 709-26. PMID 9581763 DOI: 10.1016/S0896-6273(00)81010-7  0.52
1997 Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME. CREB: a major mediator of neuronal neurotrophin responses. Neuron. 19: 1031-47. PMID 9390517  0.52
1997 Finkbeiner S, Greenberg ME. Spatial features of calcium-regulated gene expression. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 657-60. PMID 9264245 DOI: 10.1002/bies.950190803  0.52
1996 Finkbeiner S, Greenberg ME. Ca(2+)-dependent routes to Ras: mechanisms for neuronal survival, differentiation, and plasticity? Neuron. 16: 233-6. PMID 8789937 DOI: 10.1016/S0896-6273(00)80040-9  0.52
1996 Finkbeiner S. Neurotrophins and the synapse Neuroscientist. 2: 139-142.  0.52
1993 Finkbeiner SM. Glial calcium Glia. 9: 83-104. PMID 8244537  0.52
1992 van den Pol AN, Finkbeiner SM, Cornell-Bell AH. Calcium excitability and oscillations in suprachiasmatic nucleus neurons and glia in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2648-64. PMID 1351936  0.52
1992 Finkbeiner S. Calcium waves in astrocytes-filling in the gaps Neuron. 8: 1101-1108. PMID 1351732 DOI: 10.1016/0896-6273(92)90131-V  0.52
1991 Goldman RS, Finkbeiner SM, Smith SJ. Endothelin induces a sustained rise in intracellular calcium in hippocampal astrocytes Neuroscience Letters. 123: 4-8. PMID 1905789 DOI: 10.1016/0304-3940(91)90144-I  0.52
1991 Cornell-Bell AH, Finkbeiner SM. Ca2+ waves in astrocytes Cell Calcium. 12: 185-204. PMID 1647876 DOI: 10.1016/0143-4160(91)90020-F  0.52
1990 Cornell-Bell AH, Finkbeiner SM, Cooper MS, Smith SJ. Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling. Science (New York, N.Y.). 247: 470-3. PMID 1967852 DOI: 10.1126/SCIENCE.1967852  0.52
1989 Keana JF, McBurney RN, Scherz MW, Fischer JB, Hamilton PN, Smith SM, Server AC, Finkbeiner S, Stevens CF, Jahr C. Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties. Proceedings of the National Academy of Sciences of the United States of America. 86: 5631-5. PMID 2546162  0.52
1988 Goldman RS, Finkbeiner SM. Therapeutic use of magnesium sulfate in selected causes of cerebral ischemia and seizure New England Journal of Medicine. 319: 1224-1225. PMID 3173462  0.52
1988 Finkbeiner S, Stevens CF. Applications of quantitative measurements for assessing glutamate neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 85: 4071-4. PMID 2453886  0.52
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