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Changiz Taghibiglou, Pharm. D., Ph.D. - Publications

Affiliations: 
University of Saskatchewan, Saskatoon, SK, Canada 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sekar S, Marks WN, Gopalakrishnan V, Greba Q, Snutch TP, Howland JG, Taghibiglou C. Evidence for Altered Insulin Signaling in the Brains of Genetic Absence Epilepsy Rats from Strasbourg. Clinical and Experimental Pharmacology & Physiology. PMID 32304254 DOI: 10.1111/1440-1681.13326  0.552
2019 Sekar S, Taghibiglou C. Nuclear accumulation of GAPDH, GluA2 and p53 in Post-mortem Substantia Nigral region of Patients with Parkinson's Disease. Neuroscience Letters. 134641. PMID 31759082 DOI: 10.1016/J.Neulet.2019.134641  0.317
2018 Mohammad H, Sekar S, Wei Z, Moien-Afshari F, Taghibiglou C. Perampanel but Not Amantadine Prevents Behavioral Alterations and Epileptogenesis in Pilocarpine Rat Model of Status Epilepticus. Molecular Neurobiology. PMID 30039334 DOI: 10.1007/S12035-018-1230-6  0.394
2017 Sekar S, Taghibiglou C. Elevated nuclear phosphatase and tensin homolog (PTEN) and altered insulin signaling in substantia nigral region of patients with Parkinson's disease. Neuroscience Letters. 666: 139-143. PMID 29288045 DOI: 10.1016/J.Neulet.2017.12.049  0.311
2017 Sekar S, Omran E, Gopalakrishnan V, Howland JG, Snutch TP, Taghibiglou C. Elevated sterol regulatory elementary binding protein 1 and GluA2 levels in the hippocampal nuclear fraction of Genetic Absence Epilepsy Rats from Strasbourg. Epilepsy Research. 136: 1-4. PMID 28719803 DOI: 10.1016/J.Eplepsyres.2017.07.004  0.558
2015 Pham N, Sawyer TW, Wang Y, Jazii FR, Vair C, Taghibiglou C. Primary blast-induced traumatic brain injury in rats leads to increased prion protein in plasma: a potential biomarker for blast-induced traumatic brain injury. Journal of Neurotrauma. 32: 58-65. PMID 25058115 DOI: 10.1089/Neu.2014.3471  0.579
2014 Pham N, Dhar A, Khalaj S, Desai K, Taghibiglou C. Down regulation of brain cellular prion protein in an animal model of insulin resistance: possible implication in increased prevalence of stroke in pre-diabetics/diabetics. Biochemical and Biophysical Research Communications. 448: 151-6. PMID 24780399 DOI: 10.1016/J.Bbrc.2014.04.071  0.396
2013 Cho T, Ryu JK, Taghibiglou C, Ge Y, Chan AW, Liu L, Lu J, McLarnon JG, Wang YT. Long-term potentiation promotes proliferation/survival and neuronal differentiation of neural stem/progenitor cells. Plos One. 8: e76860. PMID 24146937 DOI: 10.1371/Journal.Pone.0076860  0.715
2013 Zhang S, Taghibiglou C, Girling K, Dong Z, Lin SZ, Lee W, Shyu WC, Wang YT. Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7997-8008. PMID 23637190 DOI: 10.1523/Jneurosci.5661-12.2013  0.675
2012 Bradley CA, Peineau S, Taghibiglou C, Nicolas CS, Whitcomb DJ, Bortolotto ZA, Kaang BK, Cho K, Wang YT, Collingridge GL. A pivotal role of GSK-3 in synaptic plasticity. Frontiers in Molecular Neuroscience. 5: 13. PMID 22363262 DOI: 10.3389/Fnmol.2012.00013  0.6
2011 Yang K, Xiong W, Yang G, Kojic L, Taghibiglou C, Wang YT, Cynader M. The regulatory role of long-term depression in juvenile and adult mouse ocular dominance plasticity. Scientific Reports. 1: 203. PMID 22355718 DOI: 10.1038/Srep00203  0.546
2011 Taghibiglou C, Lu J, Mackenzie IR, Wang YT, Cashman NR. Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide. Biochemical and Biophysical Research Communications. 413: 159-63. PMID 21871872 DOI: 10.1016/J.Bbrc.2011.08.011  0.542
2009 Taghibiglou C, Martin HG, Lai TW, Cho T, Prasad S, Kojic L, Lu J, Liu Y, Lo E, Zhang S, Wu JZ, Li YP, Wen YH, Imm JH, Cynader MS, et al. Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries. Nature Medicine. 15: 1399-406. PMID 19966780 DOI: 10.1038/Nm.2064  0.75
2009 Taghibiglou C, Bradley CA, Gaertner T, Li Y, Wang Y, Wang YT. Mechanisms involved in cholesterol-induced neuronal insulin resistance. Neuropharmacology. 57: 268-76. PMID 19523477 DOI: 10.1016/J.Neuropharm.2009.05.013  0.702
2009 Taghibiglou C, Martin HG, Rose JK, Ivanova N, Lin CH, Lau HL, Rai S, Wang YT, Rankin CH. Essential role of SBP-1 activation in oxygen deprivation induced lipid accumulation and increase in body width/length ratio in Caenorhabditis elegans. Febs Letters. 583: 831-4. PMID 19187779 DOI: 10.1016/J.Febslet.2009.01.045  0.688
2008 Bradley CA, Taghibiglou C, Collingridge GL, Wang YT. Mechanisms involved in the reduction of GABAA receptor alpha1-subunit expression caused by the epilepsy mutation A322D in the trafficking-competent receptor. The Journal of Biological Chemistry. 283: 22043-50. PMID 18534981 DOI: 10.1074/Jbc.M801708200  0.537
2008 Peineau S, Bradley C, Taghibiglou C, Doherty A, Bortolotto ZA, Wang YT, Collingridge GL. The role of GSK-3 in synaptic plasticity. British Journal of Pharmacology. 153: S428-37. PMID 18311157 DOI: 10.1038/Bjp.2008.2  0.599
2007 Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T, Matthews P, Isaac JT, Bortolotto ZA, Wang YT, Collingridge GL. LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron. 53: 703-17. PMID 17329210 DOI: 10.1016/J.Neuron.2007.01.029  0.744
2006 Mielke JG, Taghibiglou C, Wang YT. Endogenous insulin signaling protects cultured neurons from oxygen-glucose deprivation-induced cell death. Neuroscience. 143: 165-73. PMID 16978790 DOI: 10.1016/J.Neuroscience.2006.07.055  0.442
2005 Mielke JG, Taghibiglou C, Liu L, Zhang Y, Jia Z, Adeli K, Wang YT. A biochemical and functional characterization of diet-induced brain insulin resistance. Journal of Neurochemistry. 93: 1568-78. PMID 15935073 DOI: 10.1111/J.1471-4159.2005.03155.X  0.582
2005 Qiu W, Taghibiglou C, Avramoglu RK, Van Iderstine SC, Naples M, Ashrafpour H, Mhapsekar S, Sato R, Adeli K. Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance. Biochemistry. 44: 3041-9. PMID 15723548 DOI: 10.1021/Bi047803+  0.344
2004 Wang Y, Ju W, Liu L, Fam S, D'Souza S, Taghibiglou C, Salter M, Wang YT. alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor (AMPAR) endocytosis is essential for N-methyl-D-aspartate-induced neuronal apoptosis. The Journal of Biological Chemistry. 279: 41267-70. PMID 15319422 DOI: 10.1074/Jbc.C400199200  0.758
2004 Ahmadian G, Ju W, Liu L, Wyszynski M, Lee SH, Dunah AW, Taghibiglou C, Wang Y, Lu J, Wong TP, Sheng M, Wang YT. Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. The Embo Journal. 23: 1040-50. PMID 14976558 DOI: 10.1038/Sj.Emboj.7600126  0.755
2003 Man HY, Wang Q, Lu WY, Ju W, Ahmadian G, Liu L, D'Souza S, Wong TP, Taghibiglou C, Lu J, Becker LE, Pei L, Liu F, Wymann MP, MacDonald JF, et al. Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons. Neuron. 38: 611-24. PMID 12765612 DOI: 10.1016/S0896-6273(03)00228-9  0.748
2002 Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism: Clinical and Experimental. 51: 409-18. PMID 11912545 DOI: 10.1053/Meta.2002.30954  0.34
2002 Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K. Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Biochemical Pharmacology. 63: 349-60. PMID 11853686 DOI: 10.1016/S0006-2952(01)00918-2  0.316
2001 Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends in Cardiovascular Medicine. 11: 170-6. PMID 11597827 DOI: 10.1016/S1050-1738(01)00084-6  0.329
2000 Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. The Journal of Biological Chemistry. 275: 8416-25. PMID 10722675 DOI: 10.1074/Jbc.275.12.8416  0.346
2000 Mangaloglu L, Van-Iderstine S, Chen B, Taghibiglou C, Cheung R, Adeli K. Effect of atorvastatin (Lipitorâ„¢) on VLDL-APOB and VLDL-triglyceride overproduction in vivo in an insulin resistant hamster model Clinical Biochemistry. 33: 233. DOI: 10.1016/S0021-9150(00)80202-6  0.301
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