John F. MacDonald - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
excitatory amino acids, LTP, excitotoxicity

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tian M, Xu J, Lei G, Lombroso PJ, Jackson MF, MacDonald JF. STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit. Scientific Reports. 6: 36684. PMID 27857196 DOI: 10.1038/srep36684  1
2015 Ostapchenko VG, Chen M, Guzman MS, Xie YF, Lavine N, Fan J, Beraldo FH, Martyn AC, Belrose JC, Mori Y, MacDonald JF, Prado VF, Prado MA, Jackson MF. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15157-69. PMID 26558786 DOI: 10.1523/JNEUROSCI.4081-14.2015  1
2014 Yang K, Lei G, Xie YF, MacDonald JF, Jackson MF. Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus. Hippocampus. 24: 1601-14. PMID 25087967 DOI: 10.1002/hipo.22339  1
2014 Xiang YY, Dong H, Yang BB, Macdonald JF, Lu WY. Interaction of acetylcholinesterase with neurexin-1β regulates glutamatergic synaptic stability in hippocampal neurons. Molecular Brain. 7: 15. PMID 24594013 DOI: 10.1186/1756-6606-7-15  1
2014 Yang K, Jackson MF, MacDonald JF. Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs). International Journal of Molecular Sciences. 15: 3003-24. PMID 24562329 DOI: 10.3390/ijms15023003  1
2013 Xie YF, Jackson MF, Macdonald JF. Optogenetics and synaptic plasticity. Acta Pharmacologica Sinica. 34: 1381-5. PMID 24162508 DOI: 10.1038/aps.2013.150  1
2013 Ostapchenko VG, Beraldo FH, Mohammad AH, Xie YF, Hirata PH, Magalhaes AC, Lamour G, Li H, Maciejewski A, Belrose JC, Teixeira BL, Fahnestock M, Ferreira ST, Cashman NR, Hajj GN, ... ... MacDonald JF, et al. The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16552-64. PMID 24133259 DOI: 10.1523/JNEUROSCI.3214-13.2013  1
2013 Vasefi MS, Yang K, Li J, Kruk JS, Heikkila JJ, Jackson MF, MacDonald JF, Beazely MA. Acute 5-HT7 receptor activation increases NMDA-evoked currents and differentially alters NMDA receptor subunit phosphorylation and trafficking in hippocampal neurons. Molecular Brain. 6: 24. PMID 23672716 DOI: 10.1186/1756-6606-6-24  1
2013 Xiang YY, Chen X, Li J, Wang S, Faclier G, Macdonald JF, Hogg JC, Orser BA, Lu WY. Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells. Anesthesiology. 118: 1065-75. PMID 23485993 DOI: 10.1097/ALN.0b013e31828e180e  1
2013 Trepanier C, Lei G, Xie YF, MacDonald JF. Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase. Scientific Reports. 3: 926. PMID 23378895 DOI: 10.1038/srep00926  1
2013 MacDonald JF, Belrose JC, Xie YF, Jackson MF. Nonselective cation channels and links to hippocampal ischemia, aging, and dementia. Advances in Experimental Medicine and Biology. 961: 433-47. PMID 23224901 DOI: 10.1007/978-1-4614-4756-6_37  1
2012 Xie Y, Jackson MF, MacDonald JF. Calcium-mediated paired pulse depression in juvenile rat dorsal striatum. Neural Regeneration Research. 7: 772-7. PMID 25737701 DOI: 10.3969/j.issn.1673-5374.2012.10.008  1
2012 Martyn AC, De Jaeger X, Magalhães AC, Kesarwani R, Gonçalves DF, Raulic S, Guzman MS, Jackson MF, Izquierdo I, Macdonald JF, Prado MA, Prado VF. Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: 17651-6. PMID 23045697 DOI: 10.1073/pnas.1215381109  1
2012 Belrose JC, Xie YF, Gierszewski LJ, MacDonald JF, Jackson MF. Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons. Molecular Brain. 5: 11. PMID 22487454 DOI: 10.1186/1756-6606-5-11  1
2012 Yang K, Trepanier C, Sidhu B, Xie YF, Li H, Lei G, Salter MW, Orser BA, Nakazawa T, Yamamoto T, Jackson MF, Macdonald JF. Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases. The Embo Journal. 31: 805-16. PMID 22187052 DOI: 10.1038/emboj.2011.453  1
2012 Trepanier CH, Jackson MF, MacDonald JF. Regulation of NMDA receptors by the tyrosine kinase Fyn. The Febs Journal. 279: 12-9. PMID 21985328 DOI: 10.1111/j.1742-4658.2011.08391.x  1
2011 Xie YF, Belrose JC, Lei G, Tymianski M, Mori Y, Macdonald JF, Jackson MF. Dependence of NMDA/GSK-3β mediated metaplasticity on TRPM2 channels at hippocampal CA3-CA1 synapses. Molecular Brain. 4: 44. PMID 22188973 DOI: 10.1186/1756-6606-4-44  1
2011 Chen X, Li M, Xiong ZG, Orser BA, Macdonald JF, Lu WY. An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 249-56. PMID 22162781  1
2011 Yang K, Belrose J, Trepanier CH, Lei G, Jackson MF, MacDonald JF. Fyn, a potential target for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 243-52. PMID 21799250 DOI: 10.3233/JAD-2011-110353  1
2011 Chen X, Whissell P, Orser BA, MacDonald JF. Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. Plos One. 6: e21970. PMID 21789198 DOI: 10.1371/journal.pone.0021970  1
2011 Li HB, Jackson MF, Yang K, Trepanier C, Salter MW, Orser BA, Macdonald JF. Plasticity of synaptic GluN receptors is required for the Src-dependent induction of long-term potentiation at CA3-CA1 synapses. Hippocampus. 21: 1053-61. PMID 20865743 DOI: 10.1002/hipo.20818  1
2011 Chen X, Li M, Xiong ZG, Orser BA, MacDonald JF, Lu WY. An anti-coagulation agent futhan preferentially targets GABA A receptors in lung epithelia: Implication in treating asthma International Journal of Physiology, Pathophysiology and Pharmacology. 3: 249-256.  1
2010 Xie YF, Macdonald JF, Jackson MF. TRPM2, calcium and neurodegenerative diseases. International Journal of Physiology, Pathophysiology and Pharmacology. 2: 95-103. PMID 21383889  1
2010 Chen X, Numata T, Li M, Mori Y, Orser BA, Jackson MF, Xiong ZG, MacDonald JF. The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations. Molecular Brain. 3: 38. PMID 21122141 DOI: 10.1186/1756-6606-3-38  1
2010 Chen X, Orser BA, MacDonald JF. Design and screening of ASIC inhibitors based on aromatic diamidines for combating neurological disorders. European Journal of Pharmacology. 648: 15-23. PMID 20854810 DOI: 10.1016/j.ejphar.2010.09.005  1
2010 Yang K, Lei G, Jackson MF, Macdonald JF. The involvement of PACAP/VIP system in the synaptic transmission in the hippocampus. Journal of Molecular Neuroscience : Mn. 42: 319-26. PMID 20414742 DOI: 10.1007/s12031-010-9372-7  1
2010 Martin LJ, Zurek AA, MacDonald JF, Roder JC, Jackson MF, Orser BA. Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5269-82. PMID 20392949 DOI: 10.1523/JNEUROSCI.4209-09.2010  1
2010 Chen X, Qiu L, Li M, Dürrnagel S, Orser BA, Xiong ZG, MacDonald JF. Diarylamidines: high potency inhibitors of acid-sensing ion channels. Neuropharmacology. 58: 1045-53. PMID 20114056 DOI: 10.1016/j.neuropharm.2010.01.011  1
2010 Bartos JA, Ulrich JD, Li H, Beazely MA, Chen Y, Macdonald JF, Hell JW. Postsynaptic clustering and activation of Pyk2 by PSD-95. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 449-63. PMID 20071509 DOI: 10.1523/JNEUROSCI.4992-08.2010  1
2009 Li GH, Jackson MF, Orser BA, Macdonald JF. Reciprocal and activity-dependent regulation of surface AMPA and NMDA receptors in cultured neurons. International Journal of Physiology, Pathophysiology and Pharmacology. 2: 47-56. PMID 21383896  1
2009 Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, Macdonald JF, Tymianski M. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nature Neuroscience. 12: 1300-7. PMID 19734892 DOI: 10.1038/nn.2395  1
2009 Zahir T, Chen YF, MacDonald JF, Leipzig N, Tator CH, Shoichet MS. Neural stem/progenitor cells differentiate in vitro to neurons by the combined action of dibutyryl cAMP and interferon-gamma. Stem Cells and Development. 18: 1423-32. PMID 19355840 DOI: 10.1089/scd.2008.0412  1
2009 Yang K, Trepanier CH, Li H, Beazely MA, Lerner EA, Jackson MF, MacDonald JF. Vasoactive intestinal peptide acts via multiple signal pathways to regulate hippocampal NMDA receptors and synaptic transmission. Hippocampus. 19: 779-89. PMID 19173226 DOI: 10.1002/hipo.20559  1
2009 Ju YH, Guzzo A, Chiu MW, Taylor P, Moran MF, Gurd JW, MacDonald JF, Orser BA. Distinct properties of murine alpha 5 gamma-aminobutyric acid type a receptors revealed by biochemical fractionation and mass spectroscopy. Journal of Neuroscience Research. 87: 1737-47. PMID 19156871 DOI: 10.1002/jnr.21991  1
2009 Olah ME, Jackson MF, Li H, Perez Y, Sun HS, Kiyonaka S, Mori Y, Tymianski M, MacDonald JF. Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. The Journal of Physiology. 587: 965-79. PMID 19124544 DOI: 10.1113/jphysiol.2008.162289  1
2009 Beazely MA, Lim A, Li H, Trepanier C, Chen X, Sidhu B, Macdonald JF. Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons. The Journal of Biological Chemistry. 284: 8054-63. PMID 19106110 DOI: 10.1074/jbc.M805384200  1
2008 Beazely MA, Weerapura M, MacDonald JF. Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons. Molecular Brain. 1: 20. PMID 19077273 DOI: 10.1186/1756-6606-1-20  1
2008 Thompson RJ, Jackson MF, Olah ME, Rungta RL, Hines DJ, Beazely MA, MacDonald JF, MacVicar BA. Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science (New York, N.Y.). 322: 1555-9. PMID 19056988 DOI: 10.1126/science.1165209  1
2008 Xu J, Weerapura M, Ali MK, Jackson MF, Li H, Lei G, Xue S, Kwan CL, Manolson MF, Yang K, Macdonald JF, Yu XM. Control of excitatory synaptic transmission by C-terminal Src kinase. The Journal of Biological Chemistry. 283: 17503-14. PMID 18445593 DOI: 10.1074/jbc.M800917200  1
2008 Li J, Xiang YY, Ye L, Tsui LC, Macdonald JF, Hu J, Lu WY. Nonsteroidal anti-inflammatory drugs upregulate function of wild-type and mutant CFTR. The European Respiratory Journal. 32: 334-43. PMID 18385167 DOI: 10.1183/09031936.00168007  1
2007 Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF. TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proceedings of the National Academy of Sciences of the United States of America. 104: 16323-8. PMID 17913893 DOI: 10.1073/pnas.0701149104  1
2007 Bonin RP, Martin LJ, MacDonald JF, Orser BA. Alpha5GABAA receptors regulate the intrinsic excitability of mouse hippocampal pyramidal neurons. Journal of Neurophysiology. 98: 2244-54. PMID 17715197 DOI: 10.1152/jn.00482.2007  1
2007 Li GH, Jackson MF, MacDonald JF. Weighted least squares fitting with multiple templates for detection of small spontaneous signals. Journal of Neuroscience Methods. 164: 139-48. PMID 17573118 DOI: 10.1016/j.jneumeth.2007.04.010  1
2007 Setiawan E, Jackson MF, MacDonald JF, Matthews SG. Effects of repeated prenatal glucocorticoid exposure on long-term potentiation in the juvenile guinea-pig hippocampus. The Journal of Physiology. 581: 1033-42. PMID 17412773 DOI: 10.1113/jphysiol.2006.127381  1
2007 Caraiscos VB, Bonin RP, Newell JG, Czerwinska E, Macdonald JF, Orser BA. Insulin increases the potency of glycine at ionotropic glycine receptors. Molecular Pharmacology. 71: 1277-87. PMID 17308032 DOI: 10.1124/mol.106.033563  1
2007 MacDonald JF, Jackson MF. Transient receptor potential channels of the melastatin family and ischemic responses of central neurons. Stroke; a Journal of Cerebral Circulation. 38: 665-9. PMID 17261711 DOI: 10.1161/01.STR.0000251671.77351.e2  1
2007 MacDonald JF, Jackson MF, Beazely MA. G protein-coupled receptors control NMDARs and metaplasticity in the hippocampus. Biochimica Et Biophysica Acta. 1768: 941-51. PMID 17261268 DOI: 10.1016/j.bbamem.2006.12.006  1
2006 MacDonald JF, Jackson MF, Beazely MA. Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors. Critical Reviews in Neurobiology. 18: 71-84. PMID 17725510  1
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, ... ... MacDonald JF, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  1
2006 Beazely MA, Tong A, Wei WL, Van Tol H, Sidhu B, MacDonald JF. D2-class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet-derived growth factor receptor-dependent. Journal of Neurochemistry. 98: 1657-63. PMID 16879713 DOI: 10.1111/j.1471-4159.2006.04064.x  1
2006 Cheng VY, Bonin RP, Chiu MW, Newell JG, MacDonald JF, Orser BA. Gabapentin increases a tonic inhibitory conductance in hippocampal pyramidal neurons. Anesthesiology. 105: 325-33. PMID 16871066 DOI: 10.1097/00000542-200608000-00015  1
2006 Cheng VY, Martin LJ, Elliott EM, Kim JH, Mount HT, Taverna FA, Roder JC, Macdonald JF, Bhambri A, Collinson N, Wafford KA, Orser BA. Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3713-20. PMID 16597725 DOI: 10.1523/JNEUROSCI.5024-05.2006  1
2006 Jackson MF, Konarski JZ, Weerapura M, Czerwinski W, MacDonald JF. Protein kinase C enhances glycine-insensitive desensitization of NMDA receptors independently of previously identified protein kinase C sites. Journal of Neurochemistry. 96: 1509-18. PMID 16417568 DOI: 10.1111/j.1471-4159.2006.03651.x  1
2006 MacDonald JF, Xiong ZG, Jackson MF. Paradox of Ca2+ signaling, cell death and stroke. Trends in Neurosciences. 29: 75-81. PMID 16376999 DOI: 10.1016/j.tins.2005.12.001  1
2005 Erdeljan P, Andrews MH, MacDonald JF, Matthews SG. Glucocorticoids and serotonin alter glucocorticoid receptor mRNA levels in fetal guinea-pig hippocampal neurons, in vitro. Reproduction, Fertility, and Development. 17: 743-9. PMID 16364229 DOI: 10.1071/RD05043  1
2005 Macdonald DS, Weerapura M, Beazely MA, Martin L, Czerwinski W, Roder JC, Orser BA, MacDonald JF. Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11374-84. PMID 16339032 DOI: 10.1523/JNEUROSCI.3871-05.2005  1
2005 Orser BA, Caraiscos VB, Elliott E, Cheng VY, Newell JG, MacDonald JF. Anesthetic sensitivity is reduced in hippocampal pyramidal neurons from GABAA receptor α5 subunit null mutant mice International Congress Series. 1283: 38-42. DOI: 10.1016/j.ics.2005.07.070  1
2005 Orser BA, Caraiscos VB, You-Ten EK, Cheng VY, Newell JG, MacDonald JF. The α5 GABAA receptor subunit confers resistance to isoflurane inhibition International Congress Series. 1283: 189-192. DOI: 10.1016/j.ics.2005.06.085  1
2005 MacDonald JF, Kotecha SA, Lu WY, Jackson MF. NMDA receptors: From protein-protein interactions to transactivation Synaptic Plasticity and Transsynaptic Signaling. 321-341. DOI: 10.1007/0-387-25443-9_19  1
2004 Caraiscos VB, Newell JG, You-Ten KE, Elliott EM, Rosahl TW, Wafford KA, MacDonald JF, Orser BA. Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8454-8. PMID 15456818 DOI: 10.1523/JNEUROSCI.2063-04.2004  1
2004 Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDonald JF, Wemmie JA, Price MP, Welsh MJ, Simon RP. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell. 118: 687-98. PMID 15369669 DOI: 10.1016/j.cell.2004.08.026  1
2004 Caraiscos VB, Elliott EM, You-Ten KE, Cheng VY, Belelli D, Newell JG, Jackson MF, Lambert JJ, Rosahl TW, Wafford KA, MacDonald JF, Orser BA. Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 3662-7. PMID 14993607 DOI: 10.1073/pnas.0307231101  1
2003 Arundine M, Chopra GK, Wrong A, Lei S, Aarts MM, MacDonald JF, Tymianski M. Enhanced vulnerability to NMDA toxicity in sublethal traumatic neuronal injury in vitro. Journal of Neurotrauma. 20: 1377-95. PMID 14748985 DOI: 10.1089/089771503322686166  1
2003 Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell. 115: 863-77. PMID 14697204 DOI: 10.1016/S0092-8674(03)01017-1  1
2003 Jackson MF, Joo DT, Al-Mahrouki AA, Orser BA, Macdonald JF. Desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors facilitates use-dependent inhibition by pentobarbital. Molecular Pharmacology. 64: 395-406. PMID 12869644 DOI: 10.1124/mol.64.2.395  1
2003 Kotecha SA, MacDonald JF. Signaling molecules and receptor transduction cascades that regulate NMDA receptor-mediated synaptic transmission. International Review of Neurobiology. 54: 51-106. PMID 12785285 DOI: 10.1016/S0074-7742(03)54003-X  1
2003 Chu XP, Zhu XM, Wei WL, Li GH, Simon RP, MacDonald JF, Xiong ZG. Acidosis decreases low Ca(2+)-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons. The Journal of Physiology. 550: 385-99. PMID 12777448 DOI: 10.1113/jphysiol.2003.043091  1
2003 Man HY, Wang Q, Lu WY, Ju W, Ahmadian G, Liu L, D'Souza S, Wong TP, Taghibiglou C, Lu J, Becker LE, Pei L, Liu F, Wymann MP, MacDonald JF, et al. Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons. Neuron. 38: 611-24. PMID 12765612 DOI: 10.1016/S0896-6273(03)00228-9  1
2003 Kotecha SA, Jackson MF, Al-Mahrouki A, Roder JC, Orser BA, MacDonald JF. Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons. The Journal of Biological Chemistry. 278: 27742-9. PMID 12740378 DOI: 10.1074/jbc.M301946200  1
2003 Yeung JY, Canning KJ, Zhu G, Pennefather P, MacDonald JF, Orser BA. Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. Molecular Pharmacology. 63: 2-8. PMID 12488530 DOI: 10.1124/mol.63.1.2  1
2002 Orser BA, Canning KJ, Macdonald JF. Mechanisms of general anesthesia. Current Opinion in Anaesthesiology. 15: 427-33. PMID 17019234 DOI: 10.1097/00001503-200208000-00004  1
2002 Kotecha SA, Oak JN, Jackson MF, Perez Y, Orser BA, Van Tol HH, MacDonald JF. A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron. 35: 1111-22. PMID 12354400 DOI: 10.1016/S0896-6273(02)00859-0  1
2002 Meng Y, Zhang Y, Tregoubov V, Janus C, Cruz L, Jackson M, Lu WY, MacDonald JF, Wang JY, Falls DL, Jia Z. Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron. 35: 121-33. PMID 12123613 DOI: 10.1016/S0896-6273(02)00758-4  1
2002 Caraiscos VB, Mihic SJ, MacDonald JF, Orser BA. Tyrosine kinases enhance the function of glycine receptors in rat hippocampal neurons and human alpha(1)beta glycine receptors. The Journal of Physiology. 539: 495-502. PMID 11882681 DOI: 10.1113/jphysiol.2001.013508  1
2001 Naik V, Matsumoto E, Houston P, Hamstra S, Yeung R, Mallon J, Martire T, Zwack RM, Campbell DC, Breen TW, Yip RW, Roy JD, Girard M, Drolet P, Guay J, ... ... MacDonald JF, et al. Learning fiberoptic intubation on a simple model transfers to the O.R. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. 48: A2-A50. PMID 27688127 DOI: 10.1007/BF03028184  1
2001 MacDonald JF, Ju W, Wang YT. LTP in a culture dish. Thescientificworldjournal. 1: 213-5. PMID 12805676 DOI: 10.1100/tsw.2001.47  1
2001 Alfaidy N, Xiong ZG, Myatt L, Lye SJ, MacDonald JF, Challis JR. Prostaglandin F2alpha potentiates cortisol production by stimulating 11beta-hydroxysteroid dehydrogenase 1: a novel feedback loop that may contribute to human labor. The Journal of Clinical Endocrinology and Metabolism. 86: 5585-92. PMID 11701739 DOI: 10.1210/jcem.86.11.7995  1
2001 Xiong ZG, Chu XP, MacDonald JF. Effect of lamotrigine on the Ca(2+)-sensing cation current in cultured hippocampal neurons. Journal of Neurophysiology. 86: 2520-6. PMID 11698539  1
2001 Lei S, Czerwinska E, Czerwinski W, Walsh MP, MacDonald JF. Regulation of NMDA receptor activity by F-actin and myosin light chain kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8464-72. PMID 11606635  1
2001 MacDonald JF, Kotecha SA, Lu WY, Jackson MF. Convergence of PKC-dependent kinase signal cascades on NMDA receptors. Current Drug Targets. 2: 299-312. PMID 11554554 DOI: 10.2174/1389450013348452  1
2001 Lei S, MacDonald JF. Gadolinium reduces AMPA receptor desensitization and deactivation in hippocampal neurons. Journal of Neurophysiology. 86: 173-82. PMID 11431499  1
2001 Toong S, Xiong ZG, Zavorin SI, Bai D, Orser BA, Thatcher GR, Reynolds JN, MacDonald JF. Modulation of AMPA receptors by a novel organic nitrate. Canadian Journal of Physiology and Pharmacology. 79: 422-9. PMID 11405246 DOI: 10.1139/cjpp-79-5-422  1
2001 Joo DT, Gong D, Sonner JM, Jia Z, MacDonald JF, Eger EI, Orser BA. Blockade of AMPA receptors and volatile anesthetics: reduced anesthetic requirements in GluR2 null mutant mice for loss of the righting reflex and antinociception but not minimum alveolar concentration. Anesthesiology. 94: 478-88. PMID 11374610  1
2001 Lei S, Orser BA, Thatcher GR, Reynolds JN, MacDonald JF. Positive allosteric modulators of AMPA receptors reduce proton-induced receptor desensitization in rat hippocampal neurons. Journal of Neurophysiology. 85: 2030-8. PMID 11353019  1
2001 Erdeljan P, MacDonald JF, Matthews SG. Glucocorticoids and serotonin alter glucocorticoid receptor (GR) but not mineralocorticoid receptor (MR) mRNA levels in fetal mouse hippocampal neurons, in vitro. Brain Research. 896: 130-6. PMID 11277981 DOI: 10.1016/S0006-8993(01)02075-3  1
2001 Bai D, Zhu G, Pennefather P, Jackson MF, MacDonald JF, Orser BA. Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Molecular Pharmacology. 59: 814-24. PMID 11259626  1
2001 Huang Y, Lu W, Ali DW, Pelkey KA, Pitcher GM, Lu YM, Aoto H, Roder JC, Sasaki T, Salter MW, MacDonald JF. CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron. 29: 485-96. PMID 11239437 DOI: 10.1016/S0896-6273(01)00220-3  1
2001 Lu W, Man H, Ju W, Trimble WS, MacDonald JF, Wang YT. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron. 29: 243-54. PMID 11182095 DOI: 10.1016/S0896-6273(01)00194-5  1
2000 Lu WY, Jackson MF, Bai D, Orser BA, MacDonald JF. In CA1 pyramidal neurons of the hippocampus protein kinase C regulates calcium-dependent inactivation of NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4452-61. PMID 10844014  1
2000 Xiong Z, O'Hanlon D, Becker LE, Roder J, MacDonald JF, Marks A. Enhanced calcium transients in glial cells in neonatal cerebellar cultures derived from S100B null mice. Experimental Cell Research. 257: 281-9. PMID 10837142 DOI: 10.1006/excr.2000.4902  1
2000 Lei S, Jackson MF, Jia Z, Roder J, Bai D, Orser BA, MacDonald JF. Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG. Nature Neuroscience. 3: 559-65. PMID 10816311 DOI: 10.1038/75729  1
2000 Taverna F, Xiong ZG, Brandes L, Roder JC, Salter MW, MacDonald JF. The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. The Journal of Biological Chemistry. 275: 8475-9. PMID 10722683 DOI: 10.1074/jbc.275.12.8475  1
2000 Sattler R, Xiong Z, Lu WY, MacDonald JF, Tymianski M. Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 22-33. PMID 10627577  1
1999 Bai D, Pennefather PS, MacDonald JF, Orser BA. The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10635-46. PMID 10594047  1
1999 Xiong ZG, MacDonald JF. Sensing of extracellular calcium by neurones. Canadian Journal of Physiology and Pharmacology. 77: 715-21. PMID 10566949  1
1999 Joo DT, Xiong Z, MacDonald JF, Jia Z, Roder J, Sonner J, Orser BA. Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice. Anesthesiology. 91: 1329-41. PMID 10551584 DOI: 10.1097/00000542-199911000-00025  1
1999 Xiong ZG, Pelkey KA, Lu WY, Lu YM, Roder JC, MacDonald JF, Salter MW. Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC37. PMID 10531471  1
1999 Lei S, Lu WY, Xiong ZG, Orser BA, Valenzuela CF, MacDonald JF. Platelet-derived growth factor receptor-induced feed-forward inhibition of excitatory transmission between hippocampal pyramidal neurons. The Journal of Biological Chemistry. 274: 30617-23. PMID 10521446 DOI: 10.1074/jbc.274.43.30617  1
1999 Sattler R, Xiong Z, Lu WY, Hafner M, MacDonald JF, Tymianski M. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science (New York, N.Y.). 284: 1845-8. PMID 10364559 DOI: 10.1126/science.284.5421.1845  1
1999 Lu WY, Xiong ZG, Lei S, Orser BA, Dudek E, Browning MD, MacDonald JF. G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors. Nature Neuroscience. 2: 331-8. PMID 10204539 DOI: 10.1038/7243  1
1998 Orser BA, McAdam LC, Roder S, MacDonald JF. General anaesthetics and their effects on GABA(A) receptor desensitization. Toxicology Letters. 100: 217-24. PMID 10049145 DOI: 10.1016/S0378-4274(98)00188-X  1
1998 MacDonald JF, Xiong XG, Lu WY, Raouf R, Orser BA. Modulation of NMDA receptors. Progress in Brain Research. 116: 191-208. PMID 9932378  1
1998 McAdam LC, MacDonald JF, Orser BA. Isobolographic analysis of the interactions between midazolam and propofol at GABA(A) receptors in embryonic mouse neurons. Anesthesiology. 89: 1444-54. PMID 9856719 DOI: 10.1097/00000542-199812000-00022  1
1998 Xiong ZG, Raouf R, Lu WY, Wang LY, Orser BA, Dudek EM, Browning MD, MacDonald JF. Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. Molecular Pharmacology. 54: 1055-63. PMID 9855634  1
1998 Lu WY, Xiong ZG, Orser BA, MacDonald JF. Multiple sites of action of neomycin, Mg2+ and spermine on the NMDA receptors of rat hippocampal CA1 pyramidal neurones. The Journal of Physiology. 512: 29-46. PMID 9729615 DOI: 10.1111/j.1469-7793.1998.029bf.x  1
1997 Jarvis CR, Xiong ZG, Plant JR, Churchill D, Lu WY, MacVicar BA, MacDonald JF. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of Neurophysiology. 78: 2363-71. PMID 9356388  1
1997 Wan Q, Xiong ZG, Man HY, Ackerley CA, Braunton J, Lu WY, Becker LE, MacDonald JF, Wang YT. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature. 388: 686-90. PMID 9262404 DOI: 10.1038/41792  1
1997 Xiong Z, Lu W, MacDonald JF. Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 7012-7. PMID 9192683  0.44
1997 Orser BA, Pennefather PS, MacDonald JF. Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors. Anesthesiology. 86: 903-17. PMID 9105235 DOI: 10.1097/00000542-199704000-00021  1
1996 MacDonald JF, Browning MD, Wang LY. Long-term enhancement of excitability and the regulation of glutamate receptors by protein kinases. Epilepsy Research. Supplement. 12: 275-82. PMID 9302526  0.52
1996 Valenzuela CF, Xiong Z, MacDonald JF, Weiner JL, Frazier CJ, Dunwiddie TV, Kazlauskas A, Whiting PJ, Harris RA. Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. The Journal of Biological Chemistry. 271: 16151-9. PMID 8663218 DOI: 10.1074/jbc.271.27.16151  1
1996 Orser BA, MacDonald JF. Reconciling differences between in vitro and in vivo effects of propofol. Anesthesiology. 84: 749-50. PMID 8659808  1
1995 Orser BA, Bertlik M, Wang LY, MacDonald JF. Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones. British Journal of Pharmacology. 116: 1761-8. PMID 8528557  1
1995 Wang LY, MacDonald JF. Modulation by magnesium of the affinity of NMDA receptors for glycine in murine hippocampal neurones. The Journal of Physiology. 486: 83-95. PMID 7562646  0.52
1995 Mody I, MacDonald JF. NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release. Trends in Pharmacological Sciences. 16: 356-9. PMID 7491714 DOI: 10.1016/S0165-6147(00)89070-7  1
1994 Taverna FA, Wang LY, MacDonald JF, Hampson DR. A transmembrane model for an ionotropic glutamate receptor predicted on the basis of the location of asparagine-linked oligosaccharides. The Journal of Biological Chemistry. 269: 14159-64. PMID 8188697  1
1994 Wang LY, Orser BA, Brautigan DL, MacDonald JF. Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature. 369: 230-2. PMID 8183343 DOI: 10.1038/369230a0  1
1994 Taverna FA, Cameron BR, Hampson DL, Wang LY, MacDonald JF. Sensitivity of AMPA receptors to pentobarbital. European Journal of Pharmacology. 267: R3-5. PMID 8088363 DOI: 10.1016/0922-4106(94)90161-9  1
1994 Wang LY, Dudek EM, Browning MD, MacDonald JF. Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C. The Journal of Physiology. 475: 431-7. PMID 8006827  0.52
1994 Orser BA, Wang LY, Pennefather PS, MacDonald JF. Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7747-60. PMID 7996209  1
1994 Hochman S, Jordan LM, MacDonald JF. N-methyl-D-aspartate receptor-mediated voltage oscillations in neurons surrounding the central canal in slices of rat spinal cord. Journal of Neurophysiology. 72: 565-77. PMID 7983519  1
1994 Ross SM, Taverna FA, Pickering DS, Wang LY, MacDonald JF, Pennefather PS, Hampson DR. Expression of functional metabotropic and ionotropic glutamate receptors in baculovirus-infected insect cells. Neuroscience Letters. 173: 139-42. PMID 7936400 DOI: 10.1016/0304-3940(94)90168-6  1
1994 Tymianski M, Wang LY, MacDonald JF. Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization. Brain Research. 648: 291-5. PMID 7922543 DOI: 10.1016/0006-8993(94)91129-0  1
1993 Pickering DS, Thomsen C, Suzdak PD, Fletcher EJ, Robitaille R, Salter MW, MacDonald JF, Huang XP, Hampson DR. A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover. Journal of Neurochemistry. 61: 85-92. PMID 8390570  1
1993 Wang LY, Taverna FA, Huang XP, MacDonald JF, Hampson DR. Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase. Science (New York, N.Y.). 259: 1173-5. PMID 8382377  1
1992 Sather W, Dieudonné S, MacDonald JF, Ascher P. Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. The Journal of Physiology. 450: 643-72. PMID 1359126  1
1992 Mody I, Heinemann U, MacDonald JF, Salter MW. Recruitment of NMDA receptors into synaptic transmission after kindling-induced epilepsy and its possible mechanism. Epilepsy Research. Supplement. 8: 307-10; discussion 3. PMID 1329821  1
1992 Reynolds JN, Prasad A, MacDonald JF. Ethanol modulation of GABA receptor-activated Cl- currents in neurons of the chick, rat and mouse central nervous system. European Journal of Pharmacology. 224: 173-81. PMID 1281777  0.48
1991 MacDonald JF, Brandes L, Deverill M, Mody I, Salter MW, Theriault E. Mammalian neurons in dissociated cultures form clusters in the presence of retinal pigment epithelium. Experimental Brain Research. 83: 643-55. PMID 2026204 DOI: 10.1007/BF00229842  1
1991 MacDonald JF, Bartlett MC, Mody I, Pahapill P, Reynolds JN, Salter MW, Schneiderman JH, Pennefather PS. Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones. The Journal of Physiology. 432: 483-508. PMID 1832184  1
1991 Wang LY, Salter MW, MacDonald JF. Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science (New York, N.Y.). 253: 1132-5. PMID 1653455  1
1990 MacDonald JF, Bartlett MC, Mody I, Reynolds JN, Salter MW. The PCP site of the NMDA receptor complex. Advances in Experimental Medicine and Biology. 268: 27-34. PMID 2150154  1
1990 Mody I, Reynolds JN, Salter MW, Carlen PL, MacDonald JF. Kindling-induced epilepsy alters calcium currents in granule cells of rat hippocampal slices. Brain Research. 531: 88-94. PMID 1963106 DOI: 10.1016/0006-8993(90)90761-Y  1
1990 MacDonald JF, Nowak LM. Mechanisms of blockade of excitatory amino acid receptor channels. Trends in Pharmacological Sciences. 11: 167-72. PMID 1692173 DOI: 10.1016/0165-6147(90)90070-O  1
1989 Spielman AI, Mody I, Brand JG, Whitney G, MacDonald JF, Salter MW. A method for isolating and patch-clamping single mammalian taste receptor cells. Brain Research. 503: 326-9. PMID 2605526 DOI: 10.1016/0006-8993(89)91684-3  1
1989 Schneiderman JH, MacDonald JF. Excitatory amino acid blockers differentially affect bursting of in vitro hippocampal neurons in two pharmacological models of epilepsy. Neuroscience. 31: 593-603. PMID 2574425 DOI: 10.1016/0306-4522(89)90425-9  1
1989 MacDonald JF, Mody I, Salter MW. Regulation of N-methyl-D-aspartate receptors revealed by intracellular dialysis of murine neurones in culture. The Journal of Physiology. 414: 17-34. PMID 2558167 DOI: 10.1113/jphysiol.1989.sp017674  1
1989 Mody I, Salter MW, MacDonald JF. Whole-cell voltage-clamp recordings in granule cells acutely isolated from hippocampal slices of adult or aged rats. Neuroscience Letters. 96: 70-5. PMID 2538782 DOI: 10.1016/0304-3940(89)90245-0  1
1989 MacDonald JF, Mody I, Salter MW, Pennefather P, Schneiderman JH. The regulation of NMDA receptors in the central nervous system. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 481-8. PMID 2473487 DOI: 10.1016/0278-5846(89)90135-8  1
1988 Pennefather PS, Heisler S, MacDonald JF. A potassium conductance contributes to the action of somatostatin-14 to suppress ACTH secretion. Brain Research. 444: 346-50. PMID 2896064 DOI: 10.1016/0006-8993(88)90944-4  1
1988 Mody I, Salter MW, MacDonald JF. Requirement of NMDA receptor/channels for intracellular high-energy phosphates and the extent of intraneuronal calcium buffering in cultured mouse hippocampal neurons. Neuroscience Letters. 93: 73-8. PMID 2850518 DOI: 10.1016/0304-3940(88)90015-8  1
1987 Krnjević K, Morris ME, MacDonald JF, Ropert N. Measurements of intracellular free Ca2+ in mammalian central neurons. Canadian Journal of Physiology and Pharmacology. 65: 940-8. PMID 3621054  1
1987 Schneiderman JH, MacDonald JF. Effects of reduced magnesium on hippocampal synchrony. Brain Research. 410: 174-8. PMID 2884020 DOI: 10.1016/S0006-8993(87)80042-2  1
1987 Barker JL, Dufy B, Harrison NL, Owen DG, MacDonald JF. Signal transduction mechanisms in cultured CNS neurons and clonal pituitary cells. Neuropharmacology. 26: 941-55. PMID 2443868 DOI: 10.1016/0028-3908(87)90073-6  1
1987 MacDonald JF, Miljkovic Z, Pennefather P. Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. Journal of Neurophysiology. 58: 251-66. PMID 2443623  0.52
1987 Barker JL, Dufy B, Harrington JW, Harrison NL, MacDermott AB, MacDonald JF, Owen DG, Vicini S. Signals transduced by gamma-aminobutyric acid in cultured central nervous system neurons and thyrotropin releasing hormone in clonal pituitary cells. Annals of the New York Academy of Sciences. 494: 1-38. PMID 2440362  1
1986 MacDonald JF, Schneiderman JH, Miljkovic Z. Excitatory amino acids and regenerative activity in cultured neurons. Advances in Experimental Medicine and Biology. 203: 425-37. PMID 2878568  1
1986 MacDonald JF, Schneiderman JH. Frequency-dependent decay of calcium spikes in cultured spinal cord neurons. Neuroscience. 19: 1335-47. PMID 2434879 DOI: 10.1016/0306-4522(86)90147-8  1
1985 Honey CR, Miljkovic Z, MacDonald JF. Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid. Neuroscience Letters. 61: 135-9. PMID 2417168 DOI: 10.1016/0304-3940(85)90414-8  1
1984 MacDonald JF, Schneiderman JH. L-aspartic acid potentiates 'slow' inward current in cultured spinal cord neurons. Brain Research. 296: 350-5. PMID 6322929 DOI: 10.1016/0006-8993(84)90072-6  1
1983 MacDonald JF, Schneiderman JH. Actions of verapamil on the excitability of cultured neurones. Canadian Journal of Physiology and Pharmacology. 61: 1467-72. PMID 6671159  1
1982 MacDonald JF, Barker JL. Multiple actions of picomolar concentrations of flurazepam on the excitability of cultured mouse spinal neurons. Brain Research. 246: 257-64. PMID 7127094  1
1982 MacDonald JF, Porietis AV, Wojtowicz JM. L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons. Brain Research. 237: 248-53. PMID 7074359 DOI: 10.1016/0006-8993(82)90575-3  1
1982 Barker JL, McBurney RN, MacDonald JF. Fluctuation analysis of neutral amino acid responses in cultured mouse spinal neurones. The Journal of Physiology. 322: 365-87. PMID 6279829  1
1982 MacDonald JF, Wojtowicz JM. The effects of L-glutamate and its analogues upon the membrane conductance of central murine neurones in culture. Canadian Journal of Physiology and Pharmacology. 60: 282-96. PMID 6122493  1
1981 Nistri A, MacDonald JF, Barker JL. Effects of ibotenic acid on amphibian and mammalian spinal neurones in vitro. Advances in Biochemical Psychopharmacology. 27: 245-52. PMID 6969536  1
1981 Barker JL, MacDonald JF, Mathers DA, McBurney RN, Oertel W. GABA receptor functions in cultured mouse spinal neurons. Advances in Biochemical Psychopharmacology. 29: 281-93. PMID 6266214  1
1981 Wojtowicz JM, Gysen M, MacDonald JF. Multiple reversal potentials for responses to L-glutamic acid. Brain Research. 213: 195-200. PMID 6113033 DOI: 10.1016/0006-8993(81)91261-0  1
1980 MacDonald JF, Barker JL. Two distinct inhibitory responses of cultured, mammalian spinal neurones to ibotenic acid. Canadian Journal of Physiology and Pharmacology. 58: 1135-7. PMID 7459705  1
1980 Barker JL, MacDonald JF. Picrotoxin convulsions involve synaptic and nonsynaptic mechanisms on cultured mouse spinal neurons. Science (New York, N.Y.). 208: 1054-6. PMID 7375918  1
1980 Gruol DL, Barker JL, Huang LY, MacDonald JF, Smith TG. Hydrogen ions have multiple effects on the excitability of cultured mammalian neurons. Brain Research. 183: 247-52. PMID 7357408  1
1980 MacDonald JF, Wojtowicz JM. Two conductance mechanisms activated by applications of L-glutamic, L-aspartic, DL-homocysteic, N-methyl-D-aspartic, and DL-kainic acids to cultured mammalian central neurones. Canadian Journal of Physiology and Pharmacology. 58: 1393-7. PMID 7011507  1
1980 Barker JL, Gruol DL, Huang LM, MacDonald JF, Smith TG. Peptide receptor functions on cultured spinal neurons. Advances in Biochemical Psychopharmacology. 22: 409-23. PMID 6104901  1
1979 Macdonald JF, Pearson JA. Inhibition of spinal interneuronal activity by repeated cutaneous stimulation: a possible substrate of flexor reflex habituation. Journal of Neurobiology. 10: 79-92. PMID 521811 DOI: 10.1002/neu.480100107  1
1979 Macdonald JF, Pearson JA. Some observations on habituation of the flexor reflex in the rat: the influence of strychnine, bicuculline, spinal transection, and decerebration. Journal of Neurobiology. 10: 67-78. PMID 521810 DOI: 10.1002/neu.480100106  1
1979 Krnjević K, Lamour Y, MacDonald JF, Nistri A. Effects of some divalent cations on motoneurones in cats. Canadian Journal of Physiology and Pharmacology. 57: 944-56. PMID 519537  1
1979 Krnjević K, Lamour Y, MacDonald JF, Nistri A. Depression of monosynaptic excitatory postsynaptic potentials by Mn2+ and Co2+ in cat spinal cord. Neuroscience. 4: 1331-9. PMID 492539  0.56
1979 Krnjević K, Lamour Y, MacDonald JF, Nistri A. Depression by manganese and cobalt of monosynaptic Ia excitatory postsynaptic potential in cat spinal cord [proceedings]. The Journal of Physiology. 289: 82P. PMID 458721  0.56
1979 Krnjević K, Lamour Y, MacDonald JF, Nistri A, Puil E, Werman R. Intracellular divalent cations and neuronal excitability. Canadian Journal of Physiology and Pharmacology. 57: 957-72. PMID 117890  1
1979 MacDonald JF, Barker JL, Paul SM, Marangos PJ, Skolnick P. Inosine may be an endogenous ligand for benzodiazepine receptors on cultured spinal neurons. Science (New York, N.Y.). 205: 715-7. PMID 37602  1
1978 Krnjević K, Lamour Y, MacDonald JF, Nistri A. Motoneuronal after-potentials and extracellular divalent cations. Canadian Journal of Physiology and Pharmacology. 56: 516-20. PMID 667728  1
1978 MacDonald JF, Berry MS. Further identification of multiple responses mediated by dopamine in the CNS of Planorbis corneus. Canadian Journal of Physiology and Pharmacology. 56: 7-18. PMID 638860  1
1978 MacDonald JF, Nistri A. A comparison of the action of glutamate, ibotenate and other related amino acids on feline spinal interneurones. The Journal of Physiology. 275: 449-65. PMID 633139  0.56
1978 Krnjević K, Lamour Y, MacDonald JF, Nistri A. Intracellular actions of monoamine transmitters. Canadian Journal of Physiology and Pharmacology. 56: 896-900. PMID 30529  1
1977 MacDonald JF, Nistri A. Actions of microiontophoretically applied ibotenate on cat spinal interneurones. Canadian Journal of Physiology and Pharmacology. 55: 965-7. PMID 902170  0.56
1977 MacDonald JF, Pearson JA. A progressive and cumulative suppression of the activity of spinal neurones in the nonspinal rat. Canadian Journal of Physiology and Pharmacology. 55: 125-9. PMID 843987  1
1977 MacDonald JF, Nistri A, Padjen AL. Neuronal depressant effects of diethylester derivatives of excitatory amino acids. Canadian Journal of Physiology and Pharmacology. 55: 1387-90. PMID 597786  0.56
1976 MacDonald JF. Pharmacology of dopamine receptors in the central nervous system of Planorbis corneus [proceedings]. The Journal of Physiology. 263: 205P-206P. PMID 1011152  1
1974 Pearson JA, Wills L, MacDonald JF. The effect of p-CPA and lesions of the dorsal raphe nucleus on habituation of the flexor withdrawal reflex. Brain Research. 77: 515-20. PMID 4277692 DOI: 10.1016/0006-8993(74)90642-8  1
1973 Pearson JA, MacDonald JF. Habituation and sensitization of the flexor reflex after asphyxiation of the spinal cord. Brain Research. 58: 427-35. PMID 4518841 DOI: 10.1016/0006-8993(73)90012-7  1
1973 Pearson JA, MacDonald JF. Habituation of the flexor reflex: inhibitory build-up or synaptic depression? Brain Research. 53: 451-4. PMID 4350327 DOI: 10.1016/0006-8993(73)90232-1  1
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