Hans Scholer - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Genetics, Molecular Biology, Animal Physiology Biology

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vega-Sendino M, Lüttmann FF, Olbrich T, Chen Y, Kuenne C, Stein P, Tillo D, Carey GI, Zhong J, Savy V, Radonova L, Lu T, Saykali B, Kim KP, Domingo CN, et al. The homeobox transcription factor DUXBL controls exit from totipotency. Nature Genetics. PMID 38509386 DOI: 10.1038/s41588-024-01692-z  0.313
2024 Park J, Kim J, Shin B, Schöler HR, Kim J, Kim KP. Inducing Pluripotency in Somatic Cells: Historical Perspective and Recent Advances. International Journal of Stem Cells. PMID 38281813 DOI: 10.15283/ijsc23148  0.408
2023 MacCarthy CM, Wu G, Malik V, Menuchin-Lasowski Y, Velychko T, Keshet G, Fan R, Bedzhov I, Church GM, Jauch R, Cojocaru V, Schöler HR, Velychko S. Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell. PMID 38141611 DOI: 10.1016/j.stem.2023.11.010  0.39
2023 Mavrommatis L, Jeong HW, Kindler U, Gomez-Giro G, Kienitz MC, Stehling M, Psathaki OE, Zeuschner D, Bixel MG, Han D, Morosan-Puopolo G, Gerovska D, Yang JH, Kim JB, Arauzo-Bravo MJ, et al. Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors. Elife. 12. PMID 37963071 DOI: 10.7554/eLife.87081  0.397
2023 Hu H, Ho DHH, Tan DS, MacCarthy CM, Yu CH, Weng M, Schöler HR, Jauch R. Evaluation of the determinants for improved pluripotency induction and maintenance by engineered SOX17. Nucleic Acids Research. PMID 37607832 DOI: 10.1093/nar/gkad597  0.362
2023 Xu G, Fatima A, Breitbach M, Kuzmenkin A, Fügemann CJ, Ivanyuk D, Kim KP, Cantz T, Pfannkuche K, Schöler HR, Fleischmann BK, Hescheler J, Šarić T. Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells. International Journal of Molecular Sciences. 24. PMID 37047520 DOI: 10.3390/ijms24076546  0.429
2023 Jeong D, Lee Y, Lee SW, Ham S, Lee M, Choi NY, Wu G, Scholer HR, Ko K. Homogeneity of XEN Cells Is Critical for Generation of Chemically Induced Pluripotent Stem Cells. Molecules and Cells. PMID 36852435 DOI: 10.14348/molcells.2023.2127  0.511
2022 Kim M, Park J, Kim S, Han DW, Shin B, Schöler H, Kim J, Kim KP. Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors. International Journal of Stem Cells. PMID 36581370 DOI: 10.15283/ijsc22177  0.479
2022 Sathyanarayanan A, Ing-Simmons E, Chen R, Jeong HW, Ozguldez HO, Fan R, Duethorn B, Kim KP, Kim YS, Stehling M, Brinkmann H, Schöler HR, Adams RH, Vaquerizas JM, Bedzhov I. Early developmental plasticity enables the induction of an intermediate extraembryonic cell state. Science Advances. 8: eabl9583. PMID 36332016 DOI: 10.1126/sciadv.abl9583  0.368
2022 Seo BJ, Hong TK, Yoon SH, Song JH, Uhm SJ, Song H, Hong K, Schöler HR, Do JT. Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal. International Journal of Stem Cells. PMID 36310027 DOI: 10.15283/ijsc22138  0.422
2022 Speicher AM, Korn L, Csatári J, Gonzalez-Cano L, Heming M, Thomas C, Schroeter CB, Schafflick D, Li X, Gola L, Engler A, Kaehne T, Vallier L, Meuth SG, Meyer Zu Hörste G, et al. Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123476119. PMID 36251998 DOI: 10.1073/pnas.2123476119  0.367
2022 Nam D, Park MR, Lee H, Bae SC, Gerovska D, Araúzo-Bravo MJ, Zaehres H, Schöler HR, Kim JB. Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis. Cells. 11. PMID 35883684 DOI: 10.3390/cells11142242  0.336
2022 Doeser MC, Krygin J, Röpke A, Han D, Wedlich-Söldner R, Schöler HR, Pavenstädt H, Kim KP. Generation of a human iPSC line (MPIi008-A) from a patient with Denys-Drash syndrome. Stem Cell Research. 62: 102826. PMID 35667217 DOI: 10.1016/j.scr.2022.102826  0.394
2022 Xiong L, Tolen EA, Choi J, Velychko S, Caizzi L, Velychko T, Adachi K, MacCarthy CM, Lidschreiber M, Cramer P, Schöler HR. Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. Elife. 11. PMID 35621159 DOI: 10.7554/eLife.71533  0.381
2022 Han D, Wu G, Chen R, Drexler HCA, MacCarthy CM, Kim KP, Adachi K, Gerovska D, Mavrommatis L, Bedzhov I, Araúzo-Bravo MJ, Schöler HR. A balanced Oct4 interactome is crucial for maintaining pluripotency. Science Advances. 8: eabe4375. PMID 35171666 DOI: 10.1126/sciadv.abe4375  0.346
2021 Harberts J, Bours K, Siegmund M, Hedrich C, Glatza M, Schöler HR, Haferkamp U, Pless O, Zierold R, Blick RH. Culturing human iPSC-derived neural progenitor cells on nanowire arrays: mapping the impact of nanowire length and array pitch on proliferation, viability, and membrane deformation. Nanoscale. PMID 34842880 DOI: 10.1039/d1nr04352h  0.39
2021 Mall EM, Lecanda A, Drexler HCA, Raz E, Schöler HR, Schlatt S. Heading towards a dead end: The role of DND1 in germ line differentiation of human iPSCs. Plos One. 16: e0258427. PMID 34653201 DOI: 10.1371/journal.pone.0258427  0.398
2021 Kagiwada S, Aramaki S, Wu G, Shin B, Kutejova E, Obridge D, Adachi K, Wrana JL, Hübner K, Schöler HR. YAP creates epiblast responsiveness to inductive signals for germ cell fate. Development (Cambridge, England). PMID 34528691 DOI: 10.1242/dev.199732  0.465
2021 Salewskij K, Gross-Thebing T, Ing-Simmons E, Duethorn B, Rieger B, Fan R, Chen R, Govindasamy N, Brinkmann H, Kremer L, Kuempel-Rink N, Mildner K, Zeuschner D, Stehling M, Dejosez M, et al. Ronin governs the metabolic capacity of the embryonic lineage for post-implantation development. Embo Reports. e53048. PMID 34515391 DOI: 10.15252/embr.202153048  0.337
2021 Aramaki S, Kagiwada S, Wu G, Obridge D, Adachi K, Kutejova E, Lickert H, Hübner K, Schöler HR. Residual pluripotency is required for inductive germ cell segregation. Embo Reports. e52553. PMID 34156139 DOI: 10.15252/embr.202152553  0.406
2021 Kim KP, Han DW, Kim J, Schöler HR. Biological importance of OCT transcription factors in reprogramming and development. Experimental & Molecular Medicine. PMID 34117345 DOI: 10.1038/s12276-021-00637-4  0.39
2021 Kim KP, Li C, Bunina D, Jeong HW, Ghelman J, Yoon J, Shin B, Park H, Han DW, Zaugg JB, Kim J, Kuhlmann T, Adams RH, Noh KM, Goldman SA, et al. Donor cell memory confers a metastable state of directly converted cells. Cell Stem Cell. PMID 33848472 DOI: 10.1016/j.stem.2021.02.023  0.327
2021 Tan DS, Chen Y, Gao Y, Bednarz A, Wei Y, Malik V, Ho DH, Weng M, Ho SY, Srivastava Y, Velychko S, Yang X, Fan L, Kim J, Graumann J, et al. Directed evolution of an enhanced POU reprogramming factor for cell fate engineering. Molecular Biology and Evolution. PMID 33720298 DOI: 10.1093/molbev/msab075  0.394
2021 Hermann A, Wu G, Nedvetsky PI, Brücher VC, Egbring C, Bonse J, Höffken V, Wennmann DO, Marks M, Krahn MP, Schöler H, Heiduschka P, Pavenstädt H, Kremerskothen J. The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice. Cell Death & Disease. 12: 117. PMID 33483469 DOI: 10.1038/s41419-021-03409-0  0.312
2020 Kim KP, Yoon J, Kim J, Röpke A, Shin B, Wook Han D, Greber B, Schöler HR. Generation of a human iPSC line (MPIi007-A) from a patient with Metachromatic leukodystrophy. Stem Cell Research. 48: 101993. PMID 32950023 DOI: 10.1016/j.scr.2020.101993  0.414
2020 Kim KP, Yoon J, Shin B, Röpke A, Han DW, Schöler HR. Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease. Stem Cell Research. 46: 101839. PMID 32446239 DOI: 10.1016/j.scr.2020.101839  0.404
2020 Choi NY, Bang JS, Park YS, Lee M, Hwang HS, Ko K, Myung SC, Tapia N, Schöler HR, Kim GJ, Ko K. Generation of human androgenetic induced pluripotent stem cells. Scientific Reports. 10: 3614. PMID 32109236 DOI: 10.1038/s41598-020-60363-1  0.415
2019 Velychko S, Adachi K, Kim KP, Hou Y, MacCarthy CM, Wu G, Schöler HR. Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs. Cell Stem Cell. PMID 31708402 DOI: 10.1016/j.stem.2019.10.002  0.451
2019 Chen K, Long Q, Xing G, Wang T, Wu Y, Li L, Qi J, Zhou Y, Ma B, Schöler HR, Nie J, Pei D, Liu X. Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming. The Embo Journal. e99165. PMID 31571238 DOI: 10.15252/Embj.201899165  0.33
2019 Park MR, Wong MS, Araúzo-Bravo MJ, Lee H, Nam D, Park SY, Seo HD, Lee SM, Zeilhofer HF, Zaehres H, Schöler HR, Kim JB. Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model. Plos One. 14: e0221085. PMID 31404112 DOI: 10.1371/journal.pone.0221085  0.304
2019 Velychko S, Kang K, Kim SM, Kwak TH, Kim KP, Park C, Hong K, Chung C, Hyun JK, MacCarthy CM, Wu G, Schöler HR, Han DW. Fusion of Reprogramming Factors Alters the Trajectory of Somatic Lineage Conversion. Cell Reports. 27: 30-39.e4. PMID 30943410 DOI: 10.1016/j.celrep.2019.03.023  0.454
2018 Im JH, Hwang SI, Kim JW, Park SJ, Kang KR, You JS, Kim KP, Moon SH, Cha HJ, Chung HM, Schöler HR, Hyun JK, Han DW. Inhibition of BET selectively eliminates undifferentiated pluripotent stem cells. Science Bulletin. 63: 477-487. PMID 36658808 DOI: 10.1016/j.scib.2018.02.023  0.449
2018 Lee Y, Kim CY, Lee HJ, Kim JG, Han DW, Ko K, Walter J, Chung HM, Schöler HR, Bae YM, Ko K. Two-Step Generation of Oligodendrocyte Progenitor Cells From Mouse Fibroblasts for Spinal Cord Injury. Frontiers in Cellular Neuroscience. 12: 198. PMID 30090058 DOI: 10.3389/fncel.2018.00198  0.304
2018 Lee SW, Wu G, Choi NY, Lee HJ, Bang JS, Lee Y, Lee M, Ko K, Schöler HR, Ko K. Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells without Microenvironment of Feeder Cells. Molecules and Cells. PMID 29991673 DOI: 10.14348/molcells.2018.2294  0.523
2018 Lim KT, Kim J, Hwang SI, Zhang L, Han H, Bae D, Kim KP, Hu YP, Schöler HR, Lee I, Hui L, Han DW. Direct Conversion of Mouse Fibroblasts into Cholangiocyte Progenitor Cells. Stem Cell Reports. PMID 29606616 DOI: 10.1016/J.Stemcr.2018.03.002  0.468
2017 Totonchi M, Hassani SN, Sharifi-Zarchi A, Tapia N, Adachi K, Arand J, Greber B, Sabour D, Araúzo-Bravo MJ, Walter J, Pakzad M, Gourabi H, Schöler HR, Baharvand H. Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation. Stem Cell Reports. PMID 28919260 DOI: 10.1016/j.stemcr.2017.08.006  0.418
2017 Kessel KU, Bluemke A, Schöler HR, Zaehres H, Schlenke P, Dorn I. Emergence of CD43-Expressing Hematopoietic Progenitors from Human Induced Pluripotent Stem Cells. Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie. 44: 143-150. PMID 28626365 DOI: 10.1159/000477357  0.471
2017 Ursu A, Schöler HR, Waldmann H. Small-molecule phenotypic screening with stem cells. Nature Chemical Biology. 13: 560-563. PMID 28514421 DOI: 10.1038/Nchembio.2383  0.418
2017 Hallmann AL, Araúzo-Bravo MJ, Mavrommatis L, Ehrlich M, Röpke A, Brockhaus J, Missler M, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H, Hargus G. Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein. Scientific Reports. 7: 42991. PMID 28256506 DOI: 10.1038/Srep42991  0.343
2017 Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, et al. Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28246330 DOI: 10.1073/Pnas.1614412114  0.359
2017 Wu G, Lei L, Schöler HR. Totipotency in the mouse. Journal of Molecular Medicine (Berlin, Germany). PMID 28102431 DOI: 10.1007/s00109-017-1509-5  0.365
2016 Choi HW, Joo JY, Hong YJ, Kim JS, Song H, Lee JW, Wu G, Schöler HR, Do JT. Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency. Stem Cell Reports. 7: 911-926. PMID 28157483 DOI: 10.1016/j.stemcr.2016.09.012  0.531
2016 Jerabek S, Ng CK, Wu G, Arauzo-Bravo MJ, Kim KP, Esch D, Malik V, Chen Y, Velychko S, MacCarthy CM, Yang X, Cojocaru V, Schöler HR, Jauch R. Changing POU dimerization preferences converts Oct6 into a pluripotency inducer. Embo Reports. PMID 28007765 DOI: 10.15252/Embr.201642958  0.306
2016 Chen K, Long Q, Wang T, Zhao D, Zhou Y, Qi J, Wu Y, Li S, Chen C, Zeng X, Yang J, Zhou Z, Qin W, Liu X, Li Y, et al. Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. Embo Reports. PMID 27702986 DOI: 10.15252/Embr.201642402  0.374
2016 Kim SM, Lim KT, Kwak TH, Lee SC, Im JH, Hali S, Hwang SI, Kim D, Hwang J, Kim KP, Chung HJ, Kim JB, Ko K, Chung HM, Lee HT, et al. Corrigendum to "Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status" [Stem Cell Res. 16(2) (2016) 460-468]. Stem Cell Research. 17: 203. PMID 27594676 DOI: 10.1016/j.scr.2016.06.009  0.456
2016 Tapia N, Schöler HR. Molecular Obstacles to Clinical Translation of iPSCs. Cell Stem Cell. PMID 27452174 DOI: 10.1016/j.stem.2016.06.017  0.359
2016 Kim SM, Kim JW, Kwak TH, Park SW, Kim KP, Park H, Lim KT, Kang K, Kim J, Yang JH, Han H, Lee I, Hyun JK, Bae YM, Schöler HR, et al. Generation of Integration-free Induced Neural Stem Cells from Mouse Fibroblasts. The Journal of Biological Chemistry. PMID 27189941 DOI: 10.1074/Jbc.M115.713578  0.366
2016 Hallmann AL, Araúzo-Bravo MJ, Zerfass C, Senner V, Ehrlich M, Psathaki OE, Han DW, Tapia N, Zaehres H, Schöler HR, Kuhlmann T, Hargus G. Comparative transcriptome analysis in induced neural stem cells reveals defined neural cell identities in vitro and after transplantation into the adult rodent brain. Stem Cell Research. 16: 776-781. PMID 27153350 DOI: 10.1016/j.scr.2016.04.015  0.451
2016 Illich DJ, Zhang M, Ursu A, Osorno R, Kim KP, Yoon J, Araúzo-Bravo MJ, Wu G, Esch D, Sabour D, Colby D, Grassme KS, Chen J, Greber B, Höing S, et al. Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Reports. PMID 27149845 DOI: 10.1016/J.Celrep.2016.03.073  0.378
2016 Ursu A, Illich DJ, Takemoto Y, Porfetye AT, Zhang M, Brockmeyer A, Janning P, Watanabe N, Osada H, Vetter IR, Ziegler S, Schöler HR, Waldmann H. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chemical Biology. PMID 27049670 DOI: 10.1016/J.Chembiol.2016.02.015  0.481
2016 Hermann A, Kim JB, Srimasorn S, Zaehres H, Reinhardt P, Schöler HR, Storch A. Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors. Stem Cells International. 2016: 4736159. PMID 26977154 DOI: 10.1155/2016/4736159  0.343
2016 Wu G, Schöler HR. Lineage Segregation in the Totipotent Embryo. Current Topics in Developmental Biology. 117: 301-17. PMID 26969985 DOI: 10.1016/bs.ctdb.2015.10.014  0.306
2016 Lee HJ, Choi NY, Lee SW, Ko K, Hwang TS, Han DW, Lim J, Schöler HR, Ko K. Epigenetic alteration of imprinted genes during neural differentiation of germline-derived pluripotent stem cells. Epigenetics. 0. PMID 26962997 DOI: 10.1080/15592294.2016.1146852  0.407
2016 Kim SM, Lim KT, Kwak TH, Lee SC, Im JH, Hali S, In Hwang S, Kim D, Hwang J, Kim KP, Chung HJ, Kim JB, Ko K, Chung HM, Lee HT, et al. Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status. Stem Cell Research. 16: 460-468. PMID 26930613 DOI: 10.1016/j.scr.2016.02.025  0.419
2016 Lee H, Nam D, Choi JK, Araúzo-Bravo MJ, Kwon SY, Zaehres H, Lee T, Park CY, Kang HW, Schöler HR, Kim JB. Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene. Scientific Reports. 6: 20708. PMID 26846167 DOI: 10.1038/srep20708  0.351
2015 Russell R, Ilg M, Lin Q, Wu G, Lechel A, Bergmann W, Eiseler T, Linta L, Kumar P P, Klingenstein M, Adachi K, Hohwieler M, Sakk O, Raab S, Moon A, et al. A Dynamic Role of TBX3 in the Pluripotency Circuitry. Stem Cell Reports. 5: 1155-1170. PMID 26651606 DOI: 10.1016/j.stemcr.2015.11.003  0.45
2015 Kim J, Kim KP, Lim KT, Lee SC, Yoon J, Song G, Hwang SI, Schöler HR, Cantz T, Han DW. Generation of integration-free induced hepatocyte-like cells from mouse fibroblasts. Scientific Reports. 5: 15706. PMID 26503743 DOI: 10.1038/srep15706  0.333
2015 Tapia N, MacCarthy C, Esch D, Gabriele Marthaler A, Tiemann U, Araúzo-Bravo MJ, Jauch R, Cojocaru V, Schöler HR. Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency. Scientific Reports. 5: 13533. PMID 26314899 DOI: 10.1038/Srep13533  0.375
2015 Sugawa F, Araúzo-Bravo MJ, Yoon J, Kim KP, Aramaki S, Wu G, Stehling M, Psathaki OE, Hübner K, Schöler HR. Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile. The Embo Journal. 34: 1009-24. PMID 25750208 DOI: 10.15252/embj.201488049  0.355
2015 Joo JY, Choi HW, Kim MJ, Zaehres H, Tapia N, Stehling M, Jung KS, Tae Do J, Schöler HR. ERRATUM: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions. Scientific Reports. 5: 8180. PMID 25677799 DOI: 10.1038/srep08180  0.422
2015 Zhang M, Schulte JS, Heinick A, Piccini I, Rao J, Quaranta R, Zeuschner D, Malan D, Kim KP, Röpke A, Sasse P, Araúzo-Bravo M, Seebohm G, Schöler H, Fabritz L, et al. Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation. Stem Cells (Dayton, Ohio). 33: 1456-69. PMID 25639979 DOI: 10.1002/Stem.1964  0.428
2015 Kim JS, Choi HW, Araúzo-Bravo MJ, Schöler HR, Do JT. Reactivation of the inactive X chromosome and post-transcriptional reprogramming of Xist in iPSCs. Journal of Cell Science. 128: 81-7. PMID 25380819 DOI: 10.1242/jcs.154294  0.47
2015 Dorn I, Klich K, Arauzo-Bravo MJ, Radstaak M, Santourlidis S, Ghanjati F, Radke TF, Psathaki OE, Hargus G, Kramer J, Einhaus M, Kim JB, Kögler G, Wernet P, Schöler HR, et al. Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin. Haematologica. 100: 32-41. PMID 25326431 DOI: 10.3324/haematol.2014.108068  0.481
2015 López-Iglesias P, Alcaina Y, Tapia N, Sabour D, Arauzo-Bravo MJ, Sainz de la Maza D, Berra E, O'Mara AN, Nistal M, Ortega S, Donovan PJ, Schöler HR, De Miguel MP. Hypoxia induces pluripotency in primordial germ cells by HIF1α stabilization and Oct4 deregulation. Antioxidants & Redox Signaling. 22: 205-23. PMID 25226357 DOI: 10.1089/ars.2014.5871  0.523
2014 Joo JY, Choi HW, Kim MJ, Zaehres H, Tapia N, Stehling M, Jung KS, Do JT, Schöler HR. Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions. Scientific Reports. 4: 7477. PMID 25515008 DOI: 10.1038/srep07477  0.498
2014 Hemmer K, Zhang M, van Wüllen T, Sakalem M, Tapia N, Baumuratov A, Kaltschmidt C, Kaltschmidt B, Schöler HR, Zhang W, Schwamborn JC. Induced neural stem cells achieve long-term survival and functional integration in the adult mouse brain. Stem Cell Reports. 3: 423-31. PMID 25241741 DOI: 10.1016/j.stemcr.2014.06.017  0.408
2014 Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, et al. Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain. Cell Reports. 8: 1697-703. PMID 25220454 DOI: 10.1016/j.celrep.2014.08.014  0.494
2014 Fischedick G, Wu G, Adachi K, Araúzo-Bravo MJ, Greber B, Radstaak M, Köhler G, Tapia N, Iacone R, Anastassiadis K, Schöler HR, Zaehres H. Nanog induces hyperplasia without initiating tumors. Stem Cell Research. 13: 300-15. PMID 25173648 DOI: 10.1016/j.scr.2014.08.001  0.314
2014 Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ. Germ cell nuclear factor regulates gametogenesis in developing gonads. Plos One. 9: e103985. PMID 25140725 DOI: 10.1371/journal.pone.0103985  0.351
2014 Kim KP, Schöler HR. CellNet--where your cells are standing. Cell. 158: 699-701. PMID 25126778 DOI: 10.1016/j.cell.2014.08.001  0.439
2014 Sterneckert JL, Reinhardt P, Schöler HR. Investigating human disease using stem cell models. Nature Reviews. Genetics. 15: 625-39. PMID 25069490 DOI: 10.1038/nrg3764  0.363
2014 Frankenberg SR, Frank D, Harland R, Johnson AD, Nichols J, Niwa H, Schöler HR, Tanaka E, Wylie C, Brickman JM. The POU-er of gene nomenclature. Development (Cambridge, England). 141: 2921-3. PMID 25053425 DOI: 10.1242/Dev.108407  0.315
2014 Tiemann U, Marthaler AG, Adachi K, Wu G, Fischedick GU, Araúzo-Bravo MJ, Schöler HR, Tapia N. Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Stem Cell Reports. 2: 351-65. PMID 24672757 DOI: 10.1016/j.stemcr.2014.01.005  0.422
2014 Kim SM, Flaßkamp H, Hermann A, Araúzo-Bravo MJ, Lee SC, Lee SH, Seo EH, Lee SH, Storch A, Lee HT, Schöler HR, Tapia N, Han DW. Direct conversion of mouse fibroblasts into induced neural stem cells. Nature Protocols. 9: 871-81. PMID 24651499 DOI: 10.1038/nprot.2014.056  0.511
2014 Singhal N, Esch D, Stehling M, Schöler HR. BRG1 Is Required to Maintain Pluripotency of Murine Embryonic Stem Cells. Bioresearch Open Access. 3: 1-8. PMID 24570840 DOI: 10.1089/biores.2013.0047  0.499
2014 Lojewski X, Hermann A, Wegner F, Araúzo-Bravo MJ, Hallmeyer-Elgner S, Kirsch M, Schwarz J, Schöler HR, Storch A. Human adult white matter progenitor cells are multipotent neuroprogenitors similar to adult hippocampal progenitors Stem Cells Translational Medicine. 3: 458-469. PMID 24558163 DOI: 10.5966/sctm.2013-0117  0.414
2014 Hassani SN, Totonchi M, Gourabi H, Schöler HR, Baharvand H. Signaling roadmap modulating naive and primed pluripotency. Stem Cells and Development. 23: 193-208. PMID 24147644 DOI: 10.1089/scd.2013.0368  0.482
2014 Jerabek S, Merino F, Schöler HR, Cojocaru V. OCT4: dynamic DNA binding pioneers stem cell pluripotency. Biochimica Et Biophysica Acta. 1839: 138-54. PMID 24145198 DOI: 10.1016/J.Bbagrm.2013.10.001  0.417
2014 Hassani SN, Totonchi M, Sharifi-Zarchi A, Mollamohammadi S, Pakzad M, Moradi S, Samadian A, Masoudi N, Mirshahvaladi S, Farrokhi A, Greber B, Araúzo-Bravo MJ, Sabour D, Sadeghi M, Salekdeh GH, et al. Inhibition of TGFβ signaling promotes ground state pluripotency. Stem Cell Reviews. 10: 16-30. PMID 24036899 DOI: 10.1007/s12015-013-9473-0  0.311
2013 Offen N, Flemming J, Kamawal H, Ahmad R, Wolber W, Geis C, Zaehres H, Schöler HR, Ehrenreich H, Müller AM, Sirén AL. Effects of erythropoietin in murine-induced pluripotent cell-derived panneural progenitor cells. Molecular Medicine (Cambridge, Mass.). 19: 399-408. PMID 24408113 DOI: 10.2119/molmed.2013.00136  0.515
2013 Marthaler AG, Tiemann U, Araúzo-Bravo MJ, Wu G, Zaehres H, Hyun JK, Han DW, Schöler HR, Tapia N. Reprogramming to pluripotency through a somatic stem cell intermediate. Plos One. 8: e85138. PMID 24386457 DOI: 10.1371/journal.pone.0085138  0.468
2013 Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, et al. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports. 1: 248-65. PMID 24319661 DOI: 10.1016/J.Stemcr.2013.08.002  0.406
2013 Kossack N, Terwort N, Wistuba J, Ehmcke J, Schlatt S, Schöler H, Kliesch S, Gromoll J. A combined approach facilitates the reliable detection of human spermatogonia in vitro Human Reproduction. 28: 3012-3025. PMID 24001715 DOI: 10.1093/Humrep/Det336  0.57
2013 Eggenschwiler R, Loya K, Wu G, Sharma AD, Sgodda M, Zychlinski D, Herr C, Steinemann D, Teckman J, Bals R, Ott M, Schambach A, Schöler HR, Cantz T. Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy. Stem Cells Translational Medicine. 2: 641-54. PMID 23926210 DOI: 10.5966/sctm.2013-0017  0.345
2013 Han DW, Tapia N, Araúzo-Bravo MJ, Lim KT, Kim KP, Ko K, Lee HT, Schöler HR. Sox2 Level Is a Determinant of Cellular Reprogramming Potential. Plos One. 8: e67594. PMID 23825671 DOI: 10.1371/journal.pone.0067594  0.475
2013 Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, et al. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. Plos One. 8: e59252. PMID 23533608 DOI: 10.1371/Journal.Pone.0059252  0.317
2013 Pijnappel WW, Esch D, Baltissen MP, Wu G, Mischerikow N, Bergsma AJ, van der Wal E, Han DW, Bruch Hv, Moritz S, Lijnzaad P, Altelaar AF, Sameith K, Zaehres H, Heck AJ, et al. A central role for TFIID in the pluripotent transcription circuitry. Nature. 495: 516-9. PMID 23503660 DOI: 10.1038/Nature11970  0.331
2013 Zhang M, Schöler HR, Greber B. Rapid and efficient generation of neurons from human pluripotent stem cells in a multititre plate format. Journal of Visualized Experiments : Jove. e4335. PMID 23486189 DOI: 10.3791/4335  0.302
2013 Ruiz S, Gore A, Li Z, Panopoulos AD, Montserrat N, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Schöler HR, Zhang K, Izpisua Belmonte JC. Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. Nature Communications. 4: 1382. PMID 23340422 DOI: 10.1038/ncomms2381  0.44
2013 Hoss M, Šarić T, Denecke B, Peinkofer G, Bovi M, Groll J, Ko K, Salber J, Halbach M, Schöler HR, Zenke M, Neuss S. Expansion and differentiation of germline-derived pluripotent stem cells on biomaterials. Tissue Engineering. Part A. 19: 1067-80. PMID 23234562 DOI: 10.1089/ten.TEA.2012.0185  0.444
2013 Mosca E, Cocola C, Sabour D, Pelucchi P, Bertalot G, Palumbo O, Carella M, Götte M, Schöler HR, Reinbold R, Zucchi I, Milanesi L. Overlapping genes may control reprogramming of mouse somatic cells into induced pluripotent stem cells (iPSCs) and breast cancer stem cells. In Silico Biology. 10: 207-21. PMID 22430355 DOI: 10.3233/ISB-2010-0437  0.46
2013 Dorn I, Klich K, Radstaak M, Psathaki K, Arauzo-Bravo M, Burr B, Kim JB, Kramer J, Schöler H, Zaehres H, Schlenke P. Red blood cell generation from human induced pluripotent stem cells of different donor cell type origin Experimental Hematology. 41. DOI: 10.1016/J.Exphem.2013.05.110  0.546
2012 Choi HW, Kim JS, Jang HJ, Choi S, Kim JH, Schöler HR, Do JT. Reestablishment of the inactive X chromosome to the ground state through cell fusion-induced reprogramming. Cellular and Molecular Life Sciences : Cmls. 69: 4067-77. PMID 26250157 DOI: 10.1007/s00018-012-1139-6  0.503
2012 Tapia N, Reinhardt P, Duemmler A, Wu G, Araúzo-Bravo MJ, Esch D, Greber B, Cojocaru V, Rascon CA, Tazaki A, Kump K, Voss R, Tanaka EM, Schöler HR. Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nature Communications. 3: 1279. PMID 23232409 DOI: 10.1038/Ncomms2229  0.454
2012 Höing S, Rudhard Y, Reinhardt P, Glatza M, Stehling M, Wu G, Peiker C, Böcker A, Parga JA, Bunk E, Schwamborn JC, Slack M, Sterneckert J, Schöler HR. Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell. 11: 620-32. PMID 23064101 DOI: 10.1016/j.stem.2012.07.005  0.382
2012 Hesse M, Raulf A, Pilz GA, Haberlandt C, Klein AM, Jabs R, Zaehres H, Fügemann CJ, Zimmermann K, Trebicka J, Welz A, Pfeifer A, Röll W, Kotlikoff MI, Steinhäuser C, et al. Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle. Nature Communications. 3: 1076. PMID 23011130 DOI: 10.1038/Ncomms2089  0.451
2012 Ruiz S, Diep D, Gore A, Panopoulos AD, Montserrat N, Plongthongkum N, Kumar S, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Kan NG, Schöler HR, Mercola M, et al. Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 16196-201. PMID 22991473 DOI: 10.1073/Pnas.1202352109  0.468
2012 Sabour D, Schöler HR. Reprogramming and the mammalian germline: the Weismann barrier revisited. Current Opinion in Cell Biology. 24: 716-23. PMID 22947493 DOI: 10.1016/j.ceb.2012.08.006  0.45
2012 Frank S, Zhang M, Schöler HR, Greber B. Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions. Plos One. 7: e41958. PMID 22860038 DOI: 10.1371/journal.pone.0041958  0.409
2012 Tapia N, Han DW, Schöler HR. Restoring stem cell function in aged tissues by direct reprogramming? Cell Stem Cell. 10: 653-6. PMID 22704502 DOI: 10.1016/j.stem.2012.04.010  0.377
2012 Han DW, Tapia N, Hermann A, Hemmer K, Höing S, Araúzo-Bravo MJ, Zaehres H, Wu G, Frank S, Moritz S, Greber B, Yang JH, Lee HT, Schwamborn JC, Storch A, et al. Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell. 10: 465-72. PMID 22445517 DOI: 10.1016/j.stem.2012.02.021  0.505
2012 van de Kamp J, Kramann R, Anraths J, Schöler HR, Ko K, Knüchel R, Zenke M, Neuss S, Schneider RK. Epithelial morphogenesis of germline-derived pluripotent stem cells on organotypic skin equivalents in vitro. Differentiation; Research in Biological Diversity. 83: 138-47. PMID 22364881 DOI: 10.1016/j.diff.2011.11.014  0.421
2012 Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL. Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex. Gastroenterology. 142: 907-17. PMID 22245845 DOI: 10.1053/J.Gastro.2012.01.004  0.54
2012 Löhle M, Hermann A, Glass H, Kempe A, Schwarz SC, Kim JB, Poulet C, Ravens U, Schwarz J, Schöler HR, Storch A. Differentiation efficiency of induced pluripotent stem cells depends on the number of reprogramming factors. Stem Cells (Dayton, Ohio). 30: 570-9. PMID 22213586 DOI: 10.1002/Stem.1016  0.333
2012 Hauser S, Widera D, Qunneis F, Müller J, Zander C, Greiner J, Strauss C, Lüningschrör P, Heimann P, Schwarze H, Ebmeyer J, Sudhoff H, Araúzo-Bravo MJ, Greber B, Zaehres H, et al. Isolation of novel multipotent neural crest-derived stem cells from adult human inferior turbinate. Stem Cells and Development. 21: 742-56. PMID 22128806 DOI: 10.1089/Scd.2011.0419  0.537
2012 Sterneckert J, Höing S, Schöler HR. Concise review: Oct4 and more: the reprogramming expressway. Stem Cells (Dayton, Ohio). 30: 15-21. PMID 22009686 DOI: 10.1002/stem.765  0.515
2012 Ko K, Wu G, Araúzo-Bravo MJ, Kim J, Francine J, Greber B, Mühlisch J, Joo JY, Sabour D, Frühwald MC, Tapia N, Schöler HR. Autologous pluripotent stem cells generated from adult mouse testicular biopsy. Stem Cell Reviews. 8: 435-44. PMID 21858421 DOI: 10.1007/s12015-011-9307-x  0.431
2012 Kleger A, Weidgang C, Tata P, Müller M, Schöler H, Seufferlein T, Liebau S. Tbx3 directs cell fate decision towards mesendoderm, pancreas and liver in mouse embryonic stem cells Zeitschrift Fur Gastroenterologie. 50. DOI: 10.1055/S-0032-1323939  0.523
2011 Bernemann C, Greber B, Ko K, Sterneckert J, Han DW, Araúzo-Bravo MJ, Schöler HR. Distinct developmental ground states of epiblast stem cell lines determine different pluripotency features. Stem Cells (Dayton, Ohio). 29: 1496-503. PMID 21898681 DOI: 10.1002/stem.709  0.465
2011 Wu G, Liu N, Rittelmeyer I, Sharma AD, Sgodda M, Zaehres H, Bleidissel M, Greber B, Gentile L, Han DW, Rudolph C, Steinemann D, Schambach A, Ott M, Schöler HR, et al. Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells. Plos Biology. 9: e1001099. PMID 21765802 DOI: 10.1371/journal.pbio.1001099  0.471
2011 Moon JH, Heo JS, Kim JS, Jun EK, Lee JH, Kim A, Kim J, Whang KY, Kang YK, Yeo S, Lim HJ, Han DW, Kim DW, Oh S, Yoon BS, et al. Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1. Cell Research. 21: 1305-15. PMID 21709693 DOI: 10.1038/cr.2011.107  0.556
2011 Ko K, Reinhardt P, Tapia N, Schneider RK, Araúzo-Bravo MJ, Han DW, Greber B, Kim J, Kliesch S, Zenke M, Schöler HR. Brief report: evaluating the potential of putative pluripotent cells derived from human testis. Stem Cells (Dayton, Ohio). 29: 1304-9. PMID 21656609 DOI: 10.1002/stem.671  0.347
2011 Tapia N, Araúzo-Bravo MJ, Ko K, Schöler HR. Concise review: challenging the pluripotency of human testis-derived ESC-like cells. Stem Cells (Dayton, Ohio). 29: 1165-9. PMID 21648019 DOI: 10.1002/stem.669  0.439
2011 Tiemann U, Sgodda M, Warlich E, Ballmaier M, Schöler HR, Schambach A, Cantz T. Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 426-35. PMID 21548079 DOI: 10.1002/cyto.a.21072  0.494
2011 Schöler HR. Reprogramming cell fate: a scientific journey from viral enhancers to the master gene regulator Oct4 - an interview with Hans R. Schöler. The International Journal of Developmental Biology. 54: 1685-95. PMID 21404189 DOI: 10.1387/ijdb.103248mb  0.474
2011 Psathaki OE, Hübner K, Sabour D, Sebastiano V, Wu G, Sugawa F, Wieacker P, Pennekamp P, Schöler HR. Ultrastructural characterization of mouse embryonic stem cell-derived oocytes and granulosa cells. Stem Cells and Development. 20: 2205-15. PMID 21244227 DOI: 10.1089/scd.2010.0575  0.589
2011 Nowak-Imialek M, Kues WA, Petersen B, Lucas-Hahn A, Herrmann D, Haridoss S, Oropeza M, Lemme E, Schöler HR, Carnwath JW, Niemann H. Oct4-enhanced green fluorescent protein transgenic pigs: a new large animal model for reprogramming studies. Stem Cells and Development. 20: 1563-75. PMID 21126163 DOI: 10.1089/scd.2010.0399  0.535
2011 Sabour D, Araúzo-Bravo MJ, Hübner K, Ko K, Greber B, Gentile L, Stehling M, Schöler HR. Identification of genes specific to mouse primordial germ cells through dynamic global gene expression. Human Molecular Genetics. 20: 115-25. PMID 20940145 DOI: 10.1093/hmg/ddq450  0.568
2010 Han DW, Greber B, Wu G, Tapia N, Araúzo-Bravo MJ, Ko K, Bernemann C, Stehling M, Schöler HR. Direct reprogramming of fibroblasts into epiblast stem cells. Nature Cell Biology. 13: 66-71. PMID 21131959 DOI: 10.1038/ncb2136  0.543
2010 Wu G, Gentile L, Fuchikami T, Sutter J, Psathaki K, Esteves TC, Araúzo-Bravo MJ, Ortmeier C, Verberk G, Abe K, Schöler HR. Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2. Development (Cambridge, England). 137: 4159-69. PMID 21098565 DOI: 10.1242/dev.056630  0.398
2010 Zaehres H, Kim JB, Schöler HR. Induced pluripotent stem cells. Methods in Enzymology. 476: 309-25. PMID 20691874 DOI: 10.1016/S0076-6879(10)76018-3  0.501
2010 Ko K, Araúzo-Bravo MJ, Tapia N, Kim J, Lin Q, Bernemann C, Han DW, Gentile L, Reinhardt P, Greber B, Schneider RK, Kliesch S, Zenke M, Schöler HR. Human adult germline stem cells in question. Nature. 465: E1; discussion E3. PMID 20577160 DOI: 10.1038/nature09089  0.394
2010 Zaehres H, Kögler G, Arauzo-Bravo MJ, Bleidissel M, Santourlidis S, Weinhold S, Greber B, Kim JB, Buchheiser A, Liedtke S, Eilken HM, Graffmann N, Zhao X, Meyer J, Reinhardt P, et al. Induction of pluripotency in human cord blood unrestricted somatic stem cells. Experimental Hematology. 38: 809-18, 818.e1-2. PMID 20541586 DOI: 10.1016/j.exphem.2010.05.009  0.359
2010 Ko K, Araúzo-Bravo MJ, Kim J, Stehling M, Schöler HR. Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells. Nature Protocols. 5: 921-8. PMID 20431537 DOI: 10.1038/nprot.2010.44  0.515
2010 Fernandéz-Taboada E, Moritz S, Zeuschner D, Stehling M, Schöler HR, Saló E, Gentile L. Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation. Development (Cambridge, England). 137: 1055-65. PMID 20215344 DOI: 10.1242/Dev.042564  0.431
2010 Greber B, Wu G, Bernemann C, Joo JY, Han DW, Ko K, Tapia N, Sabour D, Sterneckert J, Tesar P, Schöler HR. Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell. 6: 215-26. PMID 20207225 DOI: 10.1016/j.stem.2010.01.003  0.445
2010 Loya K, Eggenschwiler R, Ko K, Sgodda M, André F, Bleidissel M, Schöler HR, Cantz T. Hepatic differentiation of pluripotent stem cells. Biological Chemistry. 390: 1047-55. PMID 19642877 DOI: 10.1515/BC.2009.120  0.534
2010 Zeuschner D, Mildner K, Zaehres H, Schöler HR. Induced pluripotent stem cells at nanoscale. Stem Cells and Development. 19: 615-20. PMID 19527182 DOI: 10.1089/scd.2009.0159  0.53
2009 Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, Hao E, Schöler HR, Hayek A, Ding S. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (Dayton, Ohio). 27: 2992-3000. PMID 19839055 DOI: 10.1002/Stem.240  0.418
2009 Kim JB, Zaehres H, Araúzo-Bravo MJ, Schöler HR. Generation of induced pluripotent stem cells from neural stem cells. Nature Protocols. 4: 1464-70. PMID 19798081 DOI: 10.1038/nprot.2009.173  0.421
2009 Haase A, Olmer R, Schwanke K, Wunderlich S, Merkert S, Hess C, Zweigerdt R, Gruh I, Meyer J, Wagner S, Maier LS, Han DW, Glage S, Miller K, Fischer P, et al. Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell. 5: 434-41. PMID 19796623 DOI: 10.1016/j.stem.2009.08.021  0.448
2009 Kim JB, Sebastiano V, Wu G, Araúzo-Bravo MJ, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K, Bernemann C, Ortmeier C, Zenke M, et al. Oct4-induced pluripotency in adult neural stem cells. Cell. 136: 411-9. PMID 19203577 DOI: 10.1016/j.cell.2009.01.023  0.498
2008 Adjaye JA, Byskov AG, Cibelli JB, De Maria R, Minger S, Sampaolesi M, Testa G, Verfaillie C, Zernicka-Goetz M, Schöler H, Boiani M, Crosetto N, Redi CA. Pluripotency and differentiation in embryos and stem cells. The International Journal of Developmental Biology. 52: 801-9. PMID 18956312 DOI: 10.1387/Ijdb.082695Ja  0.621
2008 Schöler HR. Commentary: highlight on stem cell research. Biological Chemistry. 389: 789. PMID 18681825 DOI: 10.1515/BC.2008.091  0.394
2008 Cantz T, Bleidissel M, Stehling M, Schöler HR. In vitro differentiation of reprogrammed murine somatic cells into hepatic precursor cells. Biological Chemistry. 389: 889-96. PMID 18627307 DOI: 10.1515/BC.2008.107  0.474
2008 Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature. 454: 646-50. PMID 18594515 DOI: 10.1038/nature07061  0.52
2008 Sharma AD, Cantz T, Vogel A, Schambach A, Haridass D, Iken M, Bleidissel M, Manns MP, Schöler HR, Ott M. Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation. Cell Transplantation. 17: 313-23. PMID 18522234 DOI: 10.3727/096368908784153896  0.429
2008 Graumann J, Hubner NC, Kim JB, Ko K, Moser M, Kumar C, Cox J, Schöler H, Mann M. Stable isotope labeling by amino acids in cell culture (SILAC) and proteome quantitation of mouse embryonic stem cells to a depth of 5,111 proteins. Molecular & Cellular Proteomics : McP. 7: 672-83. PMID 18045802 DOI: 10.1074/Mcp.M700460-Mcp200  0.549
2008 Zaehres H, Schöler HR. Induction of pluripotency: from mouse to human. Cell. 131: 834-5. PMID 18045526 DOI: 10.1016/j.cell.2007.11.020  0.449
2008 Zaehres H, Do JT, Singhal N, Tapia N, Han DW, Schöler H. Genetic modulation of self renewal factors for induced reprogramming of somatic cells Cell Research. 18. DOI: 10.1038/Cr.2008.106  0.36
2007 Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S, Scholer HR, Tomilin A, Jaenisch R. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell. 1: 403-15. PMID 18159219 DOI: 10.1016/J.Stem.2007.07.020  0.505
2007 Cavaleri FM, Balbach ST, Gentile L, Jauch A, Böhm-Steuer B, Han YM, Schöler HR, Boiani M. Subsets of cloned mouse embryos and their non-random relationship to development and nuclear reprogramming. Mechanisms of Development. 125: 153-66. PMID 18054470 DOI: 10.1016/j.mod.2007.09.007  0.4
2007 Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T, Anastassiadis K, Spitzer J, Hardt SE, Schöler H, Feitsma H, Rottbauer W, Blum M, Meijlink F, et al. Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development Circulation. 115: 1830-1838. PMID 17372176 DOI: 10.1161/Circulationaha.106.637819  0.305
2007 Ko K, Schöler HR. Embryonic stem cells as a potential source of gametes. Seminars in Reproductive Medicine. 24: 322-9. PMID 17123227 DOI: 10.1055/s-2006-952157  0.479
2006 Hübner K, Kehler J, Schöler HR. Oocytes. Methods in Enzymology. 418: 284-307. PMID 17141042 DOI: 10.1016/S0076-6879(06)18017-9  0.768
2006 Ehmcke J, Hübner K, Schöler HR, Schlatt S. Spermatogonia: origin, physiology and prospects for conservation and manipulation of the male germ line. Reproduction, Fertility, and Development. 18: 7-12. PMID 16478597  0.482
2006 Tolkunova E, Cavaleri F, Eckardt S, Reinbold R, Christenson LK, Schöler HR, Tomilin A. The caudal-related protein cdx2 promotes trophoblast differentiation of mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 139-44. PMID 16210407 DOI: 10.1634/Stemcells.2005-0240  0.499
2005 Boiani M, Schöler HR. Regulatory networks in embryo-derived pluripotent stem cells. Nature Reviews. Molecular Cell Biology. 6: 872-84. PMID 16227977 DOI: 10.1038/nrm1744  0.512
2005 Kehler J, Hübner K, Garrett S, Schöler HR. Generating oocytes and sperm from embryonic stem cells. Seminars in Reproductive Medicine. 23: 222-33. PMID 16059828 DOI: 10.1055/S-2005-872450  0.776
2005 Boiani M, Gentile L, Gambles VV, Cavaleri F, Redi CA, Schöler HR. Variable reprogramming of the pluripotent stem cell marker Oct4 in mouse clones: distinct developmental potentials in different culture environments. Stem Cells (Dayton, Ohio). 23: 1089-104. PMID 15955835 DOI: 10.1634/stemcells.2004-0352  0.551
2005 Do JT, Schöler HR. Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells (Dayton, Ohio). 22: 941-9. PMID 15536185 DOI: 10.1634/stemcells.22-6-941  0.54
2005 Guo Y, Einhorn L, Kelley M, Hirota K, Yodoi J, Reinbold R, Scholer H, Ramsey H, Hromas R. Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin. Stem Cells (Dayton, Ohio). 22: 259-64. PMID 15153603 DOI: 10.1634/Stemcells.22-3-259  0.431
2004 Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, Boiani M, Lomelí H, Nagy A, McLaughlin KJ, Schöler HR, Tomilin A. Oct4 is required for primordial germ cell survival. Embo Reports. 5: 1078-83. PMID 15486564 DOI: 10.1038/Sj.Embor.7400279  0.754
2004 Catena R, Tiveron C, Ronchi A, Porta S, Ferri A, Tatangelo L, Cavallaro M, Favaro R, Ottolenghi S, Reinbold R, Schöler H, Nicolis SK. Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells. The Journal of Biological Chemistry. 279: 41846-57. PMID 15262984 DOI: 10.1074/Jbc.M405514200  0.576
2004 Pan G, Qin B, Liu N, Schöler HR, Pei D. Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation. The Journal of Biological Chemistry. 279: 37013-20. PMID 15218026 DOI: 10.1074/Jbc.M405117200  0.396
2004 Fiester A, Scholer H, Caplan A. Stem cell therapies: time to talk to the animals. Cloning and Stem Cells. 6: 3-4. PMID 15107240 DOI: 10.1089/15362300460743772  0.449
2004 Boiani M, Kehler J, Schöler HR. Activity of the Germline-Specific Oct4 -GFP Transgene in Normal and Clone Mouse Embryos Methods of Molecular Biology. 254: 1-34. PMID 15041753 DOI: 10.1385/1-59259-741-6:001  0.692
2003 Boiani M, Eckardt S, Leu NA, Schöler HR, McLaughlin KJ. Pluripotency deficit in clones overcome by clone-clone aggregation: epigenetic complementation? The Embo Journal. 22: 5304-12. PMID 14517267 DOI: 10.1093/emboj/cdg507  0.421
2003 Cavaleri F, Schöler HR. Nanog: a new recruit to the embryonic stem cell orchestra. Cell. 113: 551-2. PMID 12787492 DOI: 10.1016/s0092-8674(03)00394-5  0.497
2003 Ohbo K, Yoshida S, Ohmura M, Ohneda O, Ogawa T, Tsuchiya H, Kuwana T, Kehler J, Abe K, Schöler HR, Suda T. Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Developmental Biology. 258: 209-25. PMID 12781694 DOI: 10.1016/S0012-1606(03)00111-8  0.751
2003 Hübner K, Fuhrmann G, Christenson LK, Kehler J, Reinbold R, De La Fuente R, Wood J, Strauss JF, Boiani M, Schöler HR. Derivation of oocytes from mouse embryonic stem cells. Science (New York, N.Y.). 300: 1251-6. PMID 12730498 DOI: 10.1126/Science.1083452  0.767
2002 Pan GJ, Chang ZY, Schöler HR, Pei D. Stem cell pluripotency and transcription factor Oct4. Cell Research. 12: 321-9. PMID 12528890 DOI: 10.1038/Sj.Cr.7290134  0.516
2002 Honaramooz A, Snedaker A, Boiani M, Schöler H, Dobrinski I, Schlatt S. Sperm from neonatal mammalian testes grafted in mice Nature. 418: 778-781. PMID 12181567 DOI: 10.1038/Nature00918  0.397
2002 Szabó PE, Hübner K, Schöler H, Mann JR. Allele-specific expression of imprinted genes in mouse migratory primordial germ cells. Mechanisms of Development. 115: 157-60. PMID 12049782 DOI: 10.1016/S0925-4773(02)00087-4  0.429
2002 Boiani M, Eckardt S, Schöler HR, McLaughlin KJ. Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes & Development. 16: 1209-19. PMID 12023300 DOI: 10.1101/gad.966002  0.474
2002 Guo Y, Costa R, Ramsey H, Starnes T, Vance G, Robertson K, Kelley M, Reinbold R, Scholer H, Hromas R. The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proceedings of the National Academy of Sciences of the United States of America. 99: 3663-7. PMID 11891324 DOI: 10.1073/Pnas.062041099  0.486
2000 Kirchhof N, Carnwath JW, Lemme E, Anastassiadis K, Schöler H, Niemann H. Expression Pattern of Oct-4 in Preimplantation Embryos of Different Species Biology of Reproduction. 63: 1698-1705. PMID 11090438 DOI: 10.1095/Biolreprod63.6.1698  0.468
2000 Anderson R, Copeland TK, Schöler H, Heasman J, Wylie C. The onset of germ cell migration in the mouse embryo. Mechanisms of Development. 91: 61-68. PMID 10704831 DOI: 10.1016/S0925-4773(99)00271-3  0.516
1998 Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Schöler H, Smith A. Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 Cell. 95: 379-391. PMID 9814708 DOI: 10.1016/S0092-8674(00)81769-9  0.613
1998 Kues WA, Carnwath JW, Niemann H, Schöler H, Paul D. A vector-based selection system for totipotent porcine cell lines Theriogenology. 49: 239. DOI: 10.1016/S0093-691X(98)90592-1  0.364
1997 Brehm A, Ohbo K, Schöler H. The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain. Molecular and Cellular Biology. 17: 154-162. PMID 8972195 DOI: 10.1128/Mcb.17.1.154  0.401
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