Roya Khosravi-Far - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Oncology, Molecular Biology, Pathology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bucur O, Stancu AL, Muraru MS, Melet A, Petrescu SM, Khosravi-Far R. PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor. Discoveries (Craiova, Romania). 2. PMID 26280018 DOI: 10.15190/d.2014.8  0.306
2017 Esposti MD, Matarrese P, Tinari A, Longo A, Recalchi S, Khosravi-Far R, Malorni W, Misasi R, Garofalo T, Sorice M. Changes in membrane lipids drive increased endocytosis following Fas ligation. Apoptosis. 22: 681-695. PMID 28299505 DOI: 10.1007/S10495-017-1362-6  0.37
2015 Bucur O, Gaidos G, Yatawara A, Pennarun B, Rupasinghe C, Roux J, Andrei S, Guo B, Panaitiu A, Pellegrini M, Mierke DF, Khosravi-Far R. A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death. Scientific Reports. 5: 9893. PMID 25962125 DOI: 10.1038/Srep09893  0.432
2014 Gunda V, Bucur O, Varnau J, Borre PV, Bernasconi MJ, Khosravi-Far R, Parangi S. Blocks to thyroid cancer cell apoptosis can be overcome by inhibition of the MAPK and PI3K/AKT pathways. Cell Death and Disease. 5. PMID 24603332 DOI: 10.1038/Cddis.2014.78  0.482
2014 Sandra F, Khosravi-Far R. Ser81 Survivin Induced Protein Kinase A (PKA)-dependent Phosphatidylinositol 3-kinase (PI3K) Activity The Indonesian Biomedical Journal. 6: 157. DOI: 10.18585/Inabj.V6I3.28  0.384
2013 Pennarun B, Gaidos G, Bucur O, Tinari A, Rupasinghe C, Jin T, Dewar R, Song K, Santos MT, Malorni W, Mierke D, Khosravi-Far R. killerFLIP: a novel lytic peptide specifically inducing cancer cell death. Cell Death & Disease. 4: e894. PMID 24176852 DOI: 10.1038/Cddis.2013.401  0.41
2013 Bucur O, Stancu AL, Goganau I, Petrescu SM, Pennarun B, Bertomeu T, Dewar R, Khosravi-Far R. Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells. Plos One. 8: e77390. PMID 24155950 DOI: 10.1371/Journal.Pone.0077390  0.4
2013 Nadler M, Zabolian R, Ndebele K, bertomeu t, Bucur O, Pennarun B, Khosravi-Far R. Abstract 3058: miRNA networks mediate the tumor suppressive function of FOXO proteins. Cancer Research. 73: 3058-3058. DOI: 10.1158/1538-7445.Am2013-3058  0.326
2013 Gunda V, Bucur O, Varnau J, Lawler J, Khosravi-Far R, Parangi S. TRAIL Induced Apoptosis is Enhanced by Inhibition of the MAPK and PI3K/AKT Pathways in Thyroid Cancer Cells Journal of Surgical Research. 179: 244. DOI: 10.1016/J.Jss.2012.10.458  0.444
2012 Bucur O, Stancu AL, Khosravi-Far R, Almasan A. Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications. Cell Death & Disease. 3: e263. PMID 22297295 DOI: 10.1038/Cddis.2012.2  0.394
2011 Singh A, Plati J, Khosravi-Far R. Harnessing the tumor suppressor function of FOXO as an alternative therapeutic approach in cancer. Current Drug Targets. 12: 1311-21. PMID 21443464 DOI: 10.2174/138945011796150271  0.392
2011 Kazerounian S, Duquette M, Reyes MA, Lawler JT, Song K, Perruzzi C, Primo L, Khosravi-Far R, Bussolino F, Rabinovitz I, Lawler J. Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase. Blood. 117: 4658-66. PMID 21378271 DOI: 10.1182/Blood-2010-09-305284  0.312
2011 Plati J, Bucur O, Khosravi-Far R. Apoptotic cell signaling in cancer progression and therapy. Integrative Biology. 3: 279-296. PMID 21340093 DOI: 10.1039/C0Ib00144A  0.488
2011 Dewar R, Chen ST, Yeckes-Rodin H, Miller K, Khosravi-Far R. Bortezomib treatment causes remission in a Ph+ALL patient and reveals FoxO as a theranostic marker. Cancer Biology & Therapy. 11: 552-558. PMID 21282974 DOI: 10.4161/Cbt.11.6.14675  0.342
2011 Sandra F, Khosravi-Far R. Phosphorylated-Survivin at Ser81 Induced Protein Kinase A (PKA): A Back Loop The Indonesian Biomedical Journal. 3: 138. DOI: 10.18585/Inabj.V3I2.145  0.39
2010 Weisberg E, Choi HG, Ray A, Barrett R, Zhang J, Sim T, Zhou W, Seeliger M, Cameron M, Azam M, Fletcher JA, Debiec-Rychter M, Mayeda M, Moreno D, Kung AL, ... ... Khosravi-Far R, et al. Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants. Blood. 115: 4206-16. PMID 20299508 DOI: 10.1182/Blood-2009-11-251751  0.301
2010 Singh A, Ye M, Bucur O, Zhu S, Tanya Santos M, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R. Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. Molecular Biology of the Cell. 21: 1140-52. PMID 20110348 DOI: 10.1091/Mbc.E09-09-0795  0.369
2010 Sandra F, Khosravi-Far R. Survivin S81A Enhanced TRAIL's Activity in Inducing Apoptosis The Indonesian Biomedical Journal. 2: 7-113. DOI: 10.18585/Inabj.V2I3.124  0.47
2010 Singh A, Ye M, Song K, Bucur O, Khosravi-Far R. Abstract 4514: Proteasome inhibition causes regression of leukemia in part through regulation of forkhead tumor suppressors Cancer Research. 70: 4514-4514. DOI: 10.1158/1538-7445.Am10-4514  0.456
2010 Jin T, Kurakin A, Song K, Wang J, Santos T, Khosravi-Far R. Abstract 2909: ApoFLIP: A bioactive peptide that restarts the apoptotic machinery in cancer cells Cancer Research. 70: 2909-2909. DOI: 10.1158/1538-7445.Am10-2909  0.439
2010 Bucur O, Stancu AL, Petrescu SM, Khosravi-Far R. Abstract 205: Bortezomib and paclitaxel synergistically induce apoptosis in chronic myelogenous leukemia cells Cancer Research. 70: 205-205. DOI: 10.1158/1538-7445.Am10-205  0.411
2009 Jagani Z, Song K, Kutok JL, Dewar MR, Melet A, Santos T, Grassian A, Ghaffari S, Wu C, Yeckes-Rodin H, Rodin HY, Ren R, Miller K, Khosravi-Far R. Proteasome inhibition causes regression of leukemia and abrogates BCR-ABL-induced evasion of apoptosis in part through regulation of forkhead tumor suppressors. Cancer Research. 69: 6546-55. PMID 19654305 DOI: 10.1158/0008-5472.Can-09-0605  0.462
2009 Ren B, Song K, Parangi S, Jin T, Ye M, Humphreys R, Duquette M, Zhang X, Benhaga N, Lawler J, Khosravi-Far R. A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. Cancer Research. 69: 3856-65. PMID 19366809 DOI: 10.1158/0008-5472.Can-08-2940  0.44
2008 Esposti MD, Tour J, Ouasti S, Ivanova S, Matarrese P, Malorni W, Khosravi-Far R. Fas Death Receptor Enhances Endocytic Membrane Traffic Converging into the Golgi Region Molecular Biology of the Cell. 20: 600-615. PMID 19037097 DOI: 10.1091/Mbc.E08-09-0925  0.351
2008 Song K, Mariappan R, Khosravi-Far R. Analysis of TNF-related apoptosis-inducing ligand in vivo through bone marrow transduction and transplantation. Methods in Enzymology. 446: 315-31. PMID 18603131 DOI: 10.1016/S0076-6879(08)01619-4  0.346
2008 Khosravi-Far R, Zakeri Z, Lockshin RA, Piacentini M. Methods in enzymolology book on cell death. Methods in Enzymology. 446: xxi-xxii. PMID 18603112 DOI: 10.1016/S0076-6879(08)01626-1  0.325
2008 Ndebele K, Gona P, Jin TG, Benhaga N, Chalah A, Degli-Esposti M, Khosravi-Far R. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3. Apoptosis : An International Journal On Programmed Cell Death. 13: 845-56. PMID 18491232 DOI: 10.1007/S10495-008-0219-4  0.441
2008 Plati J, Bucur O, Khosravi-Far R. Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunities. Journal of Cellular Biochemistry. 104: 1124-49. PMID 18459149 DOI: 10.1002/jcb.21707  0.34
2008 Matarrese P, Manganelli V, Garofalo T, Tinari A, Gambardella L, Ndebele K, Khosravi-Far R, Sorice M, Esposti MD, Malorni W. Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells. Biochemical Journal. 413: 467-478. PMID 18442358 DOI: 10.1042/Bj20071704  0.414
2008 Jagani Z, Khosravi-Far R. Cancer stem cells and impaired apoptosis. Advances in Experimental Medicine and Biology. 615: 331-44. PMID 18437901 DOI: 10.1007/978-1-4020-6554-5_15  0.369
2008 Melet A, Song K, Bucur O, Jagani Z, Grassian AR, Khosravi-Far R. Apoptotic pathways in tumor progression and therapy. Advances in Experimental Medicine and Biology. 615: 47-79. PMID 18437891 DOI: 10.1007/978-1-4020-6554-5_4  0.419
2008 Chalah A, Khosravi-Far R. The mitochondrial death pathway. Advances in Experimental Medicine and Biology. 615: 25-45. PMID 18437890 DOI: 10.1007/978-1-4020-6554-5_3  0.372
2008 Jagani Z, Singh A, Khosravi-Far R. FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis. Biochimica Et Biophysica Acta. 1785: 63-84. PMID 17980712 DOI: 10.1016/J.Bbcan.2007.10.003  0.459
2007 Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. Plos One. 2: e1161. PMID 18000534 DOI: 10.1371/Journal.Pone.0001161  0.352
2007 Zhang X, Zhang L, Yang H, Huang X, Otu H, Libermann TA, DeWolf WC, Khosravi-Far R, Olumi AF. c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells. Cancer Research. 67: 9425-34. PMID 17909052 DOI: 10.1158/0008-5472.Can-07-1310  0.42
2007 Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. The Embo Journal. 26: 3410-22. PMID 17599062 DOI: 10.1038/Sj.Emboj.7601779  0.423
2007 Ouasti S, Matarrese P, Paddon R, Khosravi-Far R, Sorice M, Tinari A, Malorni W, Esposti MD. Death receptor ligation triggers membrane scrambling between Golgi and mitochondria Cell Death & Differentiation. 14: 453-461. PMID 17008914 DOI: 10.1038/Sj.Cdd.4402043  0.403
2007 Zhang X, Yang H, Zhang L, Huang X, Otu H, Libermann T, Khosravi-Far R, DeWolf WC, Olumi AF. 661: C-FOS Promotes Trail-Induced Apoptosis by Repressing C-Flip(L) Journal of Urology. 177: 222-222. DOI: 10.1016/S0022-5347(18)30901-7  0.348
2006 Song K, Benhaga N, Anderson RL, Khosravi-Far R. Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo Cancer Research. 66: 6304-6311. PMID 16778207 DOI: 10.1158/0008-5472.Can-05-3501  0.422
2006 Ren B, Yee KO, Lawler J, Khosravi-Far R. Regulation of tumor angiogenesis by thrombospondin-1. Biochimica Et Biophysica Acta. 1765: 178-88. PMID 16406676 DOI: 10.1016/J.Bbcan.2005.11.002  0.366
2006 Abe K, Kurakin A, Mohseni-Maybodi M, Kay B, Khosravi-Far R. The complexity of TNF-related apoptosis-inducing ligand Annals of the New York Academy of Sciences. 926: 52-63. PMID 11193041 DOI: 10.1111/J.1749-6632.2000.Tb05598.X  0.466
2005 Sandra F, Esposti MD, Ndebele K, Gona P, Knight D, Rosenquist M, Khosravi-Far R. Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alters Mitochondrial Membrane Lipids Cancer Research. 65: 8286-8297. PMID 16166305 DOI: 10.1158/0008-5472.Can-04-1913  0.439
2005 Goonesinghe A, Mundy ES, Smith M, Khosravi-Far R, Martinou J, Esposti MD. Pro-apoptotic Bid induces membrane perturbation by inserting selected lysolipids into the bilayer. Biochemical Journal. 387: 109-118. PMID 15500442 DOI: 10.1042/Bj20041389  0.41
2004 Khosravi-Far R, Esposti MD. Death receptor signals to mitochondria. Cancer Biology & Therapy. 3: 1051-1057. PMID 15640619 DOI: 10.4161/Cbt.3.11.1173  0.432
2004 Jin TG, Kurakin A, Benhaga N, Abe K, Mohseni M, Sandra F, Song K, Kay BK, Khosravi-Far R. Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5. The Journal of Biological Chemistry. 279: 55594-601. PMID 15485835 DOI: 10.1074/Jbc.M401056200  0.424
2004 Zhang X, Jin TG, Yang H, DeWolf WC, Khosravi-Far R, Olumi AF. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer. Cancer Research. 64: 7086-91. PMID 15466204 DOI: 10.1158/0008-5472.Can-04-1498  0.433
2004 Parangi S, Ben R, Zhang X, Galardi E, Duquette M, Peruzzi C, Lawler J, Khosravi-Far R. Proapoptotic and survival signaling pathways plays a role in thrombospondin type I repeat mediated apoptosis in human microvascular endothelial cells Journal of the American College of Surgeons. 199: 85-86. DOI: 10.1016/J.Jamcollsurg.2004.05.185  0.47
2003 Ghaffari S, Jagani Z, Kitidis C, Lodish HF, Khosravi-Far R. Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 100: 6523-8. PMID 12750477 DOI: 10.1073/Pnas.0731871100  0.459
2002 Pandey A, Dan I, Kristiansen TZ, Watanabe NM, Voldby J, Kajikawa E, Khosravi-Far R, Blagoev B, Mann M. Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. Oncogene. 21: 3939-48. PMID 12032833 DOI: 10.1038/Sj.Onc.1205478  0.362
2001 Pal S, Datta K, Khosravi-Far R, Mukhopadhyay D. Role of Protein Kinase Cζ in Ras-mediated Transcriptional Activation of Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression Journal of Biological Chemistry. 276: 2395-2403. PMID 11060301 DOI: 10.1074/Jbc.M007818200  0.343
1996 Whitehead IP, Khosravi-Far R, Kirk H, Trigo-Gonzalez G, Der CJ, Kayt R. Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors Journal of Biological Chemistry. 271: 18643-18650. PMID 8702517 DOI: 10.1074/Jbc.271.31.18643  0.32
1996 Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Molecular and Cellular Biology. 16: 3923-33. PMID 8668210 DOI: 10.1128/Mcb.16.7.3923  0.351
1996 Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. The Journal of Biological Chemistry. 271: 6497-501. PMID 8626452 DOI: 10.1074/Jbc.271.11.6497  0.361
1995 Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Molecular and Cellular Biology. 15: 6443-53. PMID 7565796 DOI: 10.1128/Mcb.15.11.6443  0.337
1994 Khosravi-Far R, Der CJ. The Ras signal transduction pathway. Cancer Metastasis Reviews. 13: 67-89. PMID 8143346 DOI: 10.1007/Bf00690419  0.389
1994 Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic ras Molecular and Cellular Biology. 14: 6848-6857. PMID 7935402 DOI: 10.1128/Mcb.14.10.6848  0.356
1992 Tisdale EJ, Bourne JR, Khosravi-Far R, Der CJ, Balch WE. GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex. The Journal of Cell Biology. 119: 749-61. PMID 1429835 DOI: 10.1083/Jcb.119.4.749  0.311
1991 Khosravi-Far R, Lutz RJ, Cox AD, Conroy L, Bourne JR, Sinensky M, Balch WE, Buss JE, Der CJ. Isoprenoid modification of rab proteins terminating in CC or CXC motifs. Proceedings of the National Academy of Sciences of the United States of America. 88: 6264-8. PMID 1648736 DOI: 10.1073/Pnas.88.14.6264  0.305
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