| Year |
Citation |
Score |
| 2020 |
Xie H, Yepuri N, Meng Q, Dhawan R, Leech CA, Chepurny OG, Holz GG, Cooney RN. Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation. Reviews in Endocrine & Metabolic Disorders. PMID 32851581 DOI: 10.1007/S11154-020-09584-3 |
0.309 |
|
| 2020 |
Borner T, Workinger JL, Tinsley IC, Fortin SM, Stein LM, Chepurny OG, Holz GG, Wierzba AJ, Gryko D, Nexø E, Shaulson ED, Bamezai A, Da Silva VAR, De Jonghe BC, Hayes MR, et al. Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis. Cell Reports. 31: 107768. PMID 32553160 DOI: 10.1016/J.Celrep.2020.107768 |
0.309 |
|
| 2019 |
Holz GG, Chepurny OG, Leech CA. "A-kinase" regulator runs amok to provide a paradigm shift in cAMP signaling. The Journal of Biological Chemistry. 294: 2247-2248. PMID 30765510 DOI: 10.1074/Jbc.H119.007622 |
0.319 |
|
| 2019 |
Chepurny OG, Matsoukas MT, Liapakis G, Leech CA, Milliken BT, Doyle RP, Holz GG. Non-conventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP. The Journal of Biological Chemistry. PMID 30622136 DOI: 10.1074/Jbc.Ra118.005682 |
0.314 |
|
| 2018 |
Wang D, Meng Q, Leech CA, Yepuri N, Zhang L, Holz GG, Wang C, Cooney RN. Alpha7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of Enteroendocrine L Cells In Vitro. Endocrinology. PMID 29992246 DOI: 10.1210/En.2018-00433 |
0.411 |
|
| 2018 |
Veluthakal R, Chepurny OG, Leech CA, Schwede F, Holz GG, Thurmond DC. Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets. Diabetes. PMID 29986926 DOI: 10.2337/Db17-1174 |
0.405 |
|
| 2018 |
Chepurny OG, Bonaccorso RL, Leech CA, Wöllert T, Langford GM, Schwede F, Roth CL, Doyle RP, Holz GG. Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors. Scientific Reports. 8: 3749. PMID 29491394 DOI: 10.1038/S41598-018-22106-1 |
0.379 |
|
| 2018 |
Mietlicki-Baase EG, Liberini CG, Workinger JL, Bonaccorso RL, Borner T, Reiner DJ, Koch-Laskowski K, McGrath LE, Lhamo R, Stein LM, De Jonghe BC, Holz GG, Roth CL, Doyle RP, Hayes MR. A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents. Diabetes, Obesity & Metabolism. PMID 29327400 DOI: 10.1111/Dom.13222 |
0.304 |
|
| 2016 |
Kolic J, Manning Fox JE, Chepurny OG, Spigelman AF, Ferdaoussi M, Schwede F, Holz GG, MacDonald PE. PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets. Molecular Metabolism. 5: 459-71. PMID 27408772 DOI: 10.1016/J.Molmet.2016.05.003 |
0.395 |
|
| 2016 |
Chepurny OG, Leech CA, Tomanik M, DiPoto MC, Li H, Han X, Meng Q, Cooney RN, Wu J, Holz GG. Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy. Scientific Reports. 6: 28934. PMID 27352904 DOI: 10.1038/Srep28934 |
0.34 |
|
| 2016 |
Chepurny OG, Holz GG, Roe MW, Leech CA. GPR119 agonist AS1269574 activates TRPA1 cation channels to stimulate GLP-1 secretion. Molecular Endocrinology (Baltimore, Md.). me20151306. PMID 27082897 DOI: 10.1210/Me.2015-1306 |
0.441 |
|
| 2015 |
Takeda Y, Shimayoshi T, Holz GG, Noma A. Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ mobilization under the control of glucagon-like peptide-1 in mouse pancreatic β-cells. American Journal of Physiology. Cell Physiology. ajpcell.00234.2015. PMID 26741144 DOI: 10.1152/Ajpcell.00234.2015 |
0.415 |
|
| 2015 |
Schwede F, Chepurny OG, Kaufholz M, Bertinetti D, Leech CA, Cabrera O, Zhu Y, Mei F, Cheng X, Manning Fox JE, MacDonald PE, Genieser HG, Herberg FW, Holz GG. Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion. Molecular Endocrinology (Baltimore, Md.). 29: 988-1005. PMID 26061564 DOI: 10.1210/Me.2014-1330 |
0.424 |
|
| 2014 |
Holz GG, Leech CA, Chepurny OG. New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice. Biochimica Et Biophysica Acta. 1842: 2593-600. PMID 24980705 DOI: 10.1016/J.Bbadis.2014.06.023 |
0.419 |
|
| 2014 |
Nadkarni P, Chepurny OG, Holz GG. Regulation of glucose homeostasis by GLP-1. Progress in Molecular Biology and Translational Science. 121: 23-65. PMID 24373234 DOI: 10.1016/B978-0-12-800101-1.00002-8 |
0.408 |
|
| 2013 |
Holz GG, Chepurny OG, Leech CA. Leptin-stimulated KATP channel trafficking: a new paradigm for β-cell stimulus-secretion coupling? Islets. 5: 229-32. PMID 24213304 DOI: 10.4161/Isl.26958 |
0.378 |
|
| 2013 |
Zippin JH, Chen Y, Straub SG, Hess KC, Diaz A, Lee D, Tso P, Holz GG, Sharp GW, Levin LR, Buck J. CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor. The Journal of Biological Chemistry. 288: 33283-91. PMID 24100033 DOI: 10.1074/Jbc.M113.510073 |
0.394 |
|
| 2013 |
Holz GG, Chepurny OG, Leech CA. Epac2A makes a new impact in β-cell biology. Diabetes. 62: 2665-6. PMID 23881198 DOI: 10.2337/Db13-0796 |
0.366 |
|
| 2013 |
Chepurny OG, Bertinetti D, Diskar M, Leech CA, Afshari P, Tsalkova T, Cheng X, Schwede F, Genieser HG, Herberg FW, Holz GG. Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag. Molecular Endocrinology (Baltimore, Md.). 27: 1267-82. PMID 23798572 DOI: 10.1210/Me.2013-1029 |
0.359 |
|
| 2013 |
Chen H, Tsalkova T, Chepurny OG, Mei FC, Holz GG, Cheng X, Zhou J. Identification and characterization of small molecules as potent and specific EPAC2 antagonists. Journal of Medicinal Chemistry. 56: 952-62. PMID 23286832 DOI: 10.1021/Jm3014162 |
0.321 |
|
| 2012 |
Tsalkova T, Mei FC, Li S, Chepurny OG, Leech CA, Liu T, Holz GG, Woods VL, Cheng X. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proceedings of the National Academy of Sciences of the United States of America. 109: 18613-8. PMID 23091014 DOI: 10.1073/Pnas.1210209109 |
0.363 |
|
| 2012 |
Smrcka AV, Brown JH, Holz GG. Role of phospholipase Cε in physiological phosphoinositide signaling networks. Cellular Signalling. 24: 1333-43. PMID 22286105 DOI: 10.1016/J.Cellsig.2012.01.009 |
0.322 |
|
| 2011 |
Leech CA, Dzhura I, Chepurny OG, Kang G, Schwede F, Genieser HG, Holz GG. Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells. Progress in Biophysics and Molecular Biology. 107: 236-47. PMID 21782840 DOI: 10.1016/J.Pbiomolbio.2011.07.005 |
0.464 |
|
| 2011 |
Dzhura I, Chepurny OG, Leech CA, Roe MW, Dzhura E, Xu X, Lu Y, Schwede F, Genieser HG, Smrcka AV, Holz GG. Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans. Islets. 3: 121-8. PMID 21478675 DOI: 10.4161/Isl.3.3.15507 |
0.43 |
|
| 2011 |
Holz GG, Dzhura I, Chepurny O, Leech CA, Dzhura E, Afshari P, Kelley GG, Roe MW, Rindler MJ, Xu X, Lu Y, Malik S, Smrcka AV. Phospholipase C-Epsilon Couples cAMP Production and Epac2 Activation to the Facilitation of Calcium-Induced Calcium Release (CICR) in Pancreatic Beta Cells Biophysical Journal. 100: 516a-517a. DOI: 10.1016/J.Bpj.2010.12.3022 |
0.39 |
|
| 2010 |
Leech CA, Chepurny OG, Holz GG. Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1. Vitamins and Hormones. 84: 279-302. PMID 21094904 DOI: 10.1016/B978-0-12-381517-0.00010-2 |
0.445 |
|
| 2010 |
Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG. Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice. The Journal of Physiology. 588: 4871-89. PMID 21041529 DOI: 10.1113/Jphysiol.2010.198424 |
0.39 |
|
| 2010 |
Leech CA, Dzhura I, Chepurny OG, Schwede F, Genieser HG, Holz GG. Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac. Islets. 2: 72-81. PMID 20428467 DOI: 10.4161/Isl.2.2.10582 |
0.393 |
|
| 2010 |
Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans. American Journal of Physiology. Endocrinology and Metabolism. 298: E622-33. PMID 20009023 DOI: 10.1152/Ajpendo.00630.2009 |
0.428 |
|
| 2010 |
Holz GG, Chepurny OG, Leech CA, Dzhura I, Kelley G, Roe MW, Dzhura E, Li X, Schwede F, Genieser H. A Permissive Role for Protein Kinase a in Support of Epac Agonist-Stimulated Human Islet Insulin Secretion Biophysical Journal. 98: 680a. DOI: 10.1016/J.Bpj.2009.12.3736 |
0.423 |
|
| 2009 |
Kelley GG, Chepurny OG, Schwede F, Genieser HG, Leech CA, Roe MW, Li X, Dzhura I, Dzhura E, Afshari P, Holz GG. Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM. Islets. 1: 260-5. PMID 21099281 DOI: 10.4161/Isl.1.3.9645 |
0.42 |
|
| 2009 |
Peyot ML, Gray JP, Lamontagne J, Smith PJ, Holz GG, Madiraju SR, Prentki M, Heart E. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. Plos One. 4: e6221. PMID 19593440 DOI: 10.1371/Journal.Pone.0006221 |
0.438 |
|
| 2009 |
Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM. The Journal of Biological Chemistry. 284: 10728-36. PMID 19244230 DOI: 10.1074/Jbc.M900166200 |
0.422 |
|
| 2009 |
Peyot ML, Gray JP, Lamontagne J, Smith PJS, Holz GG, Madiraju SRM, Prentki M, Heart E. Glucagon like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in normal rodent pancreatic beta-cells Canadian Journal of Diabetes. 33: 240. DOI: 10.1016/S1499-2671(09)33146-9 |
0.382 |
|
| 2008 |
Stanojevic V, Habener JF, Holz GG, Leech CA. Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cells. Biochemical and Biophysical Research Communications. 368: 614-9. PMID 18243136 DOI: 10.1016/J.Bbrc.2008.01.109 |
0.564 |
|
| 2008 |
Kang G, Leech CA, Chepurny OG, Coetzee WA, Holz GG. Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells. The Journal of Physiology. 586: 1307-19. PMID 18202100 DOI: 10.1113/Jphysiol.2007.143818 |
0.394 |
|
| 2008 |
Holz GG, Heart E, Leech CA. Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach". American Journal of Physiology. Cell Physiology. 294: C4-6. PMID 17989206 DOI: 10.1152/Ajpcell.00522.2007 |
0.421 |
|
| 2008 |
Holz GG, Chepurny OG, Schwede F. Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Cellular Signalling. 20: 10-20. PMID 17716863 DOI: 10.1016/J.Cellsig.2007.07.009 |
0.37 |
|
| 2007 |
Chepurny OG, Holz GG. A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts. Journal of Biomolecular Screening. 12: 740-6. PMID 17507637 DOI: 10.1177/1087057107301856 |
0.353 |
|
| 2006 |
Harbeck MC, Chepurny O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells. Science's Stke : Signal Transduction Knowledge Environment. 2006: pl6. PMID 16985238 DOI: 10.1126/Stke.3532006Pl6 |
0.323 |
|
| 2006 |
Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG. Cell physiology of cAMP sensor Epac. The Journal of Physiology. 577: 5-15. PMID 16973695 DOI: 10.1113/Jphysiol.2006.119644 |
0.42 |
|
| 2006 |
Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells. The Journal of Physiology. 573: 595-609. PMID 16613879 DOI: 10.1113/Jphysiol.2006.107391 |
0.431 |
|
| 2005 |
Landa LR, Harbeck M, Kaihara K, Chepurny O, Kitiphongspattana K, Graf O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. The Journal of Biological Chemistry. 280: 31294-302. PMID 15987680 DOI: 10.1074/Jbc.M505657200 |
0.412 |
|
| 2005 |
Kang G, Chepurny OG, Rindler MJ, Collis L, Chepurny Z, Li WH, Harbeck M, Roe MW, Holz GG. A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells. The Journal of Physiology. 566: 173-88. PMID 15860526 DOI: 10.1113/Jphysiol.2005.087510 |
0.434 |
|
| 2005 |
Holz GG, Chepurny OG. Diabetes outfoxed by GLP-1? Science's Stke : Signal Transduction Knowledge Environment. 2005: pe2. PMID 15671479 DOI: 10.1126/Stke.2682005Pe2 |
0.418 |
|
| 2004 |
Holz GG, Holz G. New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 36: 787-94. PMID 15655710 DOI: 10.1055/s-2004-826165 |
0.361 |
|
| 2004 |
Holz GG. Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell. Diabetes. 53: 5-13. PMID 14693691 DOI: 10.2337/Diabetes.53.1.5 |
0.451 |
|
| 2003 |
Holz GG, Chepurny OG. Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus. Current Medicinal Chemistry. 10: 2471-83. PMID 14529486 DOI: 10.2174/0929867033456648 |
0.426 |
|
| 2003 |
Ianus A, Holz GG, Theise ND, Hussain MA. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. The Journal of Clinical Investigation. 111: 843-50. PMID 12639990 DOI: 10.1172/Jci200316502 |
0.329 |
|
| 2003 |
Kang G, Holz GG. Amplification of exocytosis by Ca2+-induced Ca2+ release in INS-1 pancreatic beta cells. The Journal of Physiology. 546: 175-89. PMID 12509487 DOI: 10.1113/Jphysiol.2002.029959 |
0.357 |
|
| 2003 |
Kang G, Joseph JW, Chepurny OG, Monaco M, Wheeler MB, Bos JL, Schwede F, Genieser HG, Holz GG. Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells. The Journal of Biological Chemistry. 278: 8279-85. PMID 12496249 DOI: 10.1074/Jbc.M211682200 |
0.449 |
|
| 2003 |
Tsuboi T, da Silva Xavier G, Holz GG, Jouaville LS, Thomas AP, Rutter GA. Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells. The Biochemical Journal. 369: 287-99. PMID 12410638 DOI: 10.1042/Bj20021288 |
0.424 |
|
| 2002 |
Chepurny OG, Hussain MA, Holz GG. Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220. Endocrinology. 143: 2303-13. PMID 12021195 DOI: 10.1210/Endo.143.6.8870 |
0.407 |
|
| 2002 |
Chepurny OG, Holz GG. Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation. Cell and Tissue Research. 307: 191-201. PMID 11845326 DOI: 10.1007/S00441-001-0494-7 |
0.428 |
|
| 2001 |
Kang G, Chepurny OG, Holz GG. cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells. The Journal of Physiology. 536: 375-85. PMID 11600673 DOI: 10.1111/J.1469-7793.2001.0375C.Xd |
0.415 |
|
| 2000 |
Holz GG, Leech CA, Habener JF. Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic beta-cells. Biochimie. 82: 915-26. PMID 11086221 DOI: 10.1016/S0300-9084(00)01171-8 |
0.595 |
|
| 2000 |
Leech CA, Holz GG, Chepurny O, Habener JF. Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells. Biochemical and Biophysical Research Communications. 278: 44-7. PMID 11071853 DOI: 10.1006/Bbrc.2000.3763 |
0.587 |
|
| 2000 |
Skoglund G, Hussain MA, Holz GG. Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element. Diabetes. 49: 1156-64. PMID 10909973 DOI: 10.2337/Diabetes.49.7.1156 |
0.4 |
|
| 1999 |
Holz GG, Leech CA, Heller RS, Castonguay M, Habener JF. cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic beta-cells. A Ca2+ signaling system stimulated by the insulinotropic hormone glucagon-like peptide-1-(7-37). The Journal of Biological Chemistry. 274: 14147-56. PMID 10318832 DOI: 10.1074/Jbc.274.20.14147 |
0.587 |
|
| 1999 |
Seufert J, Kieffer TJ, Leech CA, Holz GG, Moritz W, Ricordi C, Habener JF. Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 84: 670-6. PMID 10022436 DOI: 10.1210/Jcem.84.2.5460 |
0.585 |
|
| 1998 |
Holz GG, Habener JF. Black widow spider alpha-latrotoxin: a presynaptic neurotoxin that shares structural homology with the glucagon-like peptide-1 family of insulin secretagogic hormones. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 121: 177-84. PMID 9972293 DOI: 10.1016/S0305-0491(98)10088-3 |
0.575 |
|
| 1997 |
Kieffer TJ, Heller RS, Leech CA, Holz GG, Habener JF. Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells. Diabetes. 46: 1087-93. PMID 9166685 DOI: 10.2337/Diab.46.6.1087 |
0.583 |
|
| 1996 |
Leech CA, Holz GG, Habener JF. Signal transduction of PACAP and GLP-1 in pancreatic beta cells. Annals of the New York Academy of Sciences. 805: 81-92; discussion 92. PMID 8993395 DOI: 10.1111/j.1749-6632.1996.tb17475.x |
0.592 |
|
| 1995 |
Leech CA, Holz GG, Habener JF. Pituitary adenylate cyclase-activating polypeptide induces the voltage-independent activation of inward membrane currents and elevation of intracellular calcium in HIT-T15 insulinoma cells. Endocrinology. 136: 1530-6. PMID 7895663 DOI: 10.1210/Endo.136.4.7895663 |
0.596 |
|
| 1995 |
Holz GG, Leech CA, Habener JF. Activation of a cAMP-regulated Ca(2+)-signaling pathway in pancreatic beta-cells by the insulinotropic hormone glucagon-like peptide-1. The Journal of Biological Chemistry. 270: 17749-57. PMID 7543091 DOI: 10.1074/Jbc.270.30.17749 |
0.598 |
|
| 1994 |
Leech CA, Holz GG. Application of patch clamp methods to the study of calcium currents and calcium channels. Methods in Cell Biology. 40: 135-51. PMID 8201974 DOI: 10.1016/S0091-679X(08)61113-9 |
0.359 |
|
| 1994 |
Leech CA, Holz GG, Habener JF. Voltage-independent calcium channels mediate slow oscillations of cytosolic calcium that are glucose dependent in pancreatic beta-cells. Endocrinology. 135: 365-72. PMID 8013370 DOI: 10.1210/Endo.135.1.8013370 |
0.577 |
|
| 1993 |
Holz GG, Kühtreiber WM, Habener JF. Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37). Nature. 361: 362-5. PMID 8381211 DOI: 10.1038/361362A0 |
0.573 |
|
| 1993 |
Holz GG, Leech CA, Kuhtreiber WM, Habener JF. Glucagon-like peptide 1 and glucose: Bidirectional signal transduction cross talk and the glucose competence concept Digestion. 54: 351. DOI: 10.1159/000201056 |
0.459 |
|
| 1992 |
Holz GG, Habener JF. Signal transduction crosstalk in the endocrine system: pancreatic beta-cells and the glucose competence concept. Trends in Biochemical Sciences. 17: 388-93. PMID 1455507 DOI: 10.1016/0968-0004(92)90006-U |
0.59 |
|
| 1989 |
Goad LJ, Berens RL, Marr JJ, Beach DH, Holz GG. The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro. Molecular and Biochemical Parasitology. 32: 179-89. PMID 2494453 DOI: 10.1016/0166-6851(89)90069-8 |
0.302 |
|
| 1989 |
Dunlap K, Holz GG, Lindgren CA, Moore JW. Calcium channels that regulate neurosecretion. Society of General Physiologists Series. 44: 239-50. PMID 2476855 |
0.481 |
|
| 1989 |
Holz GG, Kream RM, Spiegel A, Dunlap K. G proteins couple alpha-adrenergic and GABAb receptors to inhibition of peptide secretion from peripheral sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 657-66. PMID 2465394 DOI: 10.1523/Jneurosci.09-02-00657.1989 |
0.58 |
|
| 1988 |
Holz GG, Dunlap K, Kream RM. Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 463-71. PMID 2448433 DOI: 10.1523/Jneurosci.08-02-00463.1988 |
0.568 |
|
| 1987 |
Dunlap K, Holz GG, Rane SG. G proteins as regulators of ion channel function. Trends in Neurosciences. 10: 241-244. PMID 22241937 DOI: 10.1016/0166-2236(87)90166-4 |
0.542 |
|
| 1987 |
Rane SG, Holz GG, Dunlap K. Dihydropyridine inhibition of neuronal calcium current and substance P release. Pflã¼Gers Archiv : European Journal of Physiology. 409: 361-6. PMID 2442705 DOI: 10.1007/Bf00583789 |
0.583 |
|
| 1986 |
Holz GG, Shefner SA, Anderson EG. Serotonin decreases the duration of action potentials recorded from tetraethylammonium-treated bullfrog dorsal root ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 620-6. PMID 3485707 DOI: 10.1523/Jneurosci.06-03-00620.1986 |
0.537 |
|
| 1986 |
Holz GG, Rane SG, Dunlap K. GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Nature. 319: 670-2. PMID 2419757 DOI: 10.1038/319670A0 |
0.592 |
|
| 1985 |
Holz GG, Shefner SA, Anderson EG. Serotonin depolarizes type A and C primary afferents: an intracellular study in bullfrog dorsal root ganglion. Brain Research. 327: 71-9. PMID 3872695 DOI: 10.1016/0006-8993(85)91500-8 |
0.445 |
|
| 1984 |
Holz GG, Anderson EG. The actions of serotonin on frog primary afferent terminals and cell bodies. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 77: 13-21. PMID 6141866 DOI: 10.1016/0742-8413(84)90124-5 |
0.437 |
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| Show low-probability matches. |
