James W. Murrough - Publications

Affiliations: 
Psychiatry Icahn School of Medicine at Mount Sinai, New York, NY, United States 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wilkinson ST, Farmer C, Ballard E, Mathew SJ, Grunebaum MF, Murrough JW, Sos P, Wang G, Gueorguieva R, Zarate CA. Impact of midazolam vs. saline on effect size estimates in controlled trials of ketamine as a rapid-acting antidepressant. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30653192 DOI: 10.1038/s41386-019-0317-8  0.44
2019 Oh KY, Van Dam NT, Doucette JT, Murrough JW. Effects of chronic physical disease and systemic inflammation on suicide risk in patients with depression: a hospital-based case-control study. Psychological Medicine. 1-9. PMID 30606276 DOI: 10.1017/S0033291718003902  0.56
2018 Mathew SJ, Wilkinson ST, Altinay M, Asghar-Ali A, Chang LC, Collins KA, Dale RM, Hu B, Krishnan K, Kellner CH, Malone DA, Murrough JW, Ostroff RB, Sanacora G, Shao M, et al. ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol. Contemporary Clinical Trials. PMID 30572160 DOI: 10.1016/j.cct.2018.12.009  0.44
2018 Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Gruenbaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, et al. Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Translational Psychiatry. 8: 280. PMID 30552317 DOI: 10.1038/s41398-018-0311-7  0.92
2018 Tan A, Costi S, Morris LS, Van Dam NT, Kautz M, Whitton AE, Friedman AK, Collins KA, Ahle G, Chadha N, Do B, Pizzagalli DA, Iosifescu DV, Nestler EJ, Han MH, ... Murrough JW, et al. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. PMID 30385872 DOI: 10.1038/s41380-018-0283-2  0.56
2018 Stern ER, Shahab R, Grimaldi SJ, Leibu E, Murrough JW, Fleysher L, Parides MK, Coffey BJ, Burdick KE, Goodman WK. High-dose ondansetron reduces activation of interoceptive and sensorimotor brain regions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30116006 DOI: 10.1038/s41386-018-0174-x  0.44
2018 Murrough JW, Huryk KM, Mao X, Iacoviello B, Collins K, Nierenberg AA, Kang G, Shungu DC, Iosifescu DV. A pilot study of minocycline for the treatment of bipolar depression: Effects on cortical glutathione and oxidative stress in vivo. Journal of Affective Disorders. 230: 56-64. PMID 29407539 DOI: 10.1016/j.jad.2017.12.067  0.44
2017 Sayed S, Van Dam NT, Horn SR, Kautz MM, Parides M, Costi S, Collins KA, Iacoviello B, Iosifescu DV, Mathé AA, Southwick SM, Feder A, Charney DS, Murrough JW. A randomized dose-ranging study of neuropeptide Y in patients with posttraumatic stress disorder. The International Journal of Neuropsychopharmacology. PMID 29186416 DOI: 10.1093/ijnp/pyx109  0.92
2017 Murrough JW, Charney DS. Corticotropin-Releasing Factor Type 1 Receptor Antagonists for Stress-Related Disorders: Time to Call It Quits? Biological Psychiatry. 82: 858-860. PMID 29129198 DOI: 10.1016/j.biopsych.2017.10.012  0.92
2017 Fava M, Freeman MP, Flynn M, Hoeppner BB, Shelton R, Iosifescu DV, Murrough JW, Mischoulon D, Cusin C, Rapaport M, Dunlop BW, Trivedi MH, Jha M, Sanacora G, Hermes G, et al. Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD). Brain Stimulation. PMID 29030111 DOI: 10.1016/j.brs.2017.09.010  0.44
2017 Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA, Sanacora G. The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis. The American Journal of Psychiatry. appiajp201717040472. PMID 28969441 DOI: 10.1176/appi.ajp.2017.17040472  0.44
2017 Murrough JW, Wade E, Sayed S, Ahle G, Kiraly DD, Welch A, Collins KA, Soleimani L, Iosifescu DV, Charney DS. Dextromethorphan/quinidine pharmacotherapy in patients with treatment resistant depression: A proof of concept clinical trial. Journal of Affective Disorders. 218: 277-283. PMID 28478356 DOI: 10.1016/j.jad.2017.04.072  0.92
2017 Murrough JW, Abdallah CG, Mathew SJ. Targeting glutamate signalling in depression: progress and prospects. Nature Reviews. Drug Discovery. PMID 28303025 DOI: 10.1038/nrd.2017.16  0.44
2017 Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, et al. Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. Lancet (London, England). PMID 28088338 DOI: 10.1016/S0140-6736(16)31714-7  0.6
2016 Kautz M, Charney DS, Murrough JW. Neuropeptide Y, resilience, and PTSD therapeutics. Neuroscience Letters. PMID 27913193 DOI: 10.1016/j.neulet.2016.11.061  0.92
2016 Abdallah CG, Averill LA, Collins KA, Geha P, Schwartz J, Averill C, DeWilde KE, Wong E, Anticevic A, Tang CY, Iosifescu DV, Charney DS, Murrough JW. Ketamine Treatment and Global Brain Connectivity in Major Depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27604566 DOI: 10.1038/npp.2016.186  0.92
2016 Friedman AK, Juarez B, Ku SM, Zhang H, Calizo RC, Walsh JJ, Chaudhury D, Zhang S, Hawkins A, Dietz DM, Murrough JW, Ribadeneira M, Wong EH, Neve RL, Han MH. KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nature Communications. 7: 11671. PMID 27216573 DOI: 10.1038/ncomms11671  0.92
2016 Murrough JW, Abdallah CG, Anticevic A, Collins KA, Geha P, Averill LA, Schwartz J, DeWilde KE, Averill C, Jia-Wei Yang G, Wong E, Tang CY, Krystal JH, Iosifescu DV, Charney DS. Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder. Human Brain Mapping. PMID 27144347 DOI: 10.1002/hbm.23235  0.92
2016 Schwartz J, Murrough JW, Iosifescu DV. Ketamine for treatment-resistant depression: recent developments and clinical applications. Evidence-Based Mental Health. PMID 27053196 DOI: 10.1136/eb-2016-102355  0.44
2015 Costi S, Van Dam NT, Murrough JW. Current Status of Ketamine and Related Therapies for Mood and Anxiety Disorders. Current Behavioral Neuroscience Reports. 2: 216-225. PMID 26783510 DOI: 10.1007/s40473-015-0052-3  0.56
2015 Lener MS, Kundu P, Wong E, Dewilde KE, Tang CY, Balchandani P, Murrough JW. Cortical abnormalities and association with symptom dimensions across the depressive spectrum. Journal of Affective Disorders. 190: 529-536. PMID 26571102 DOI: 10.1016/j.jad.2015.10.027  0.92
2015 Murrough JW, Yaqubi S, Sayed S, Charney DS. Emerging drugs for the treatment of anxiety. Expert Opinion On Emerging Drugs. 20: 393-406. PMID 26012843 DOI: 10.1517/14728214.2015.1049996  0.92
2015 DeWilde KE, Levitch CF, Murrough JW, Mathew SJ, Iosifescu DV. The promise of ketamine for treatment-resistant depression: current evidence and future directions. Annals of the New York Academy of Sciences. 1345: 47-58. PMID 25649308 DOI: 10.1111/nyas.12646  0.92
2015 Murrough JW, Burdick KE, Levitch CF, Perez AM, Brallier JW, Chang LC, Foulkes A, Charney DS, Mathew SJ, Iosifescu DV. Neurocognitive effects of ketamine and association with antidepressant response in individuals with treatment-resistant depression: a randomized controlled trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1084-90. PMID 25374095 DOI: 10.1038/npp.2014.298  0.92
2015 Wan LB, Levitch CF, Perez AM, Brallier JW, Iosifescu DV, Chang LC, Foulkes A, Mathew SJ, Charney DS, Murrough JW. Ketamine safety and tolerability in clinical trials for treatment-resistant depression. The Journal of Clinical Psychiatry. 76: 247-52. PMID 25271445 DOI: 10.4088/JCP.13m08852  0.92
2014 Hodes GE, Pfau ML, Leboeuf M, Golden SA, Christoffel DJ, Bregman D, Rebusi N, Heshmati M, Aleyasin H, Warren BL, Lebonté B, Horn S, Lapidus KA, Stelzhammer V, Wong EH, ... ... Murrough JW, et al. Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress. Proceedings of the National Academy of Sciences of the United States of America. 111: 16136-41. PMID 25331895 DOI: 10.1073/pnas.1415191111  0.92
2014 Lapidus KA, Levitch CF, Perez AM, Brallier JW, Parides MK, Soleimani L, Feder A, Iosifescu DV, Charney DS, Murrough JW. A randomized controlled trial of intranasal ketamine in major depressive disorder. Biological Psychiatry. 76: 970-6. PMID 24821196 DOI: 10.1016/j.biopsych.2014.03.026  0.92
2014 Iacoviello BM, Wu G, Alvarez E, Huryk K, Collins KA, Murrough JW, Iosifescu DV, Charney DS. Cognitive-emotional training as an intervention for major depressive disorder. Depression and Anxiety. 31: 699-706. PMID 24753225 DOI: 10.1002/da.22266  0.92
2014 Feder A, Parides MK, Murrough JW, Perez AM, Morgan JE, Saxena S, Kirkwood K, Aan Het Rot M, Lapidus KA, Wan LB, Iosifescu D, Charney DS. Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial. Jama Psychiatry. 71: 681-8. PMID 24740528 DOI: 10.1001/jamapsychiatry.2014.62  0.92
2014 Lapidus KA, Gabbay V, Mao X, Johnson A, Murrough JW, Mathew SJ, Shungu DC. In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neuroscience Letters. 569: 74-9. PMID 24704328 DOI: 10.1016/j.neulet.2014.03.056  0.44
2014 Price RB, Iosifescu DV, Murrough JW, Chang LC, Al Jurdi RK, Iqbal SZ, Soleimani L, Charney DS, Foulkes AL, Mathew SJ. Effects of ketamine on explicit and implicit suicidal cognition: a randomized controlled trial in treatment-resistant depression. Depression and Anxiety. 31: 335-43. PMID 24668760 DOI: 10.1002/da.22253  0.92
2014 Iacoviello BM, Wu G, Abend R, Murrough JW, Feder A, Fruchter E, Levinstein Y, Wald I, Bailey CR, Pine DS, Neumeister A, Bar-Haim Y, Charney DS. Attention bias variability and symptoms of posttraumatic stress disorder. Journal of Traumatic Stress. 27: 232-9. PMID 24604631 DOI: 10.1002/jts.21899  0.92
2014 Ivanov I, Murrough JW, Bansal R, Hao X, Peterson BS. Cerebellar morphology and the effects of stimulant medications in youths with attention deficit-hyperactivity disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 718-26. PMID 24077064 DOI: 10.1038/npp.2013.257  0.92
2013 Murrough JW, Wan LB, Iacoviello B, Collins KA, Solon C, Glicksberg B, Perez AM, Mathew SJ, Charney DS, Iosifescu DV, Burdick KE. Neurocognitive effects of ketamine in treatment-resistant major depression: association with antidepressant response. Psychopharmacology. PMID 24022236 DOI: 10.1007/s00213-013-3255-x  0.92
2013 Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM, Iqbal S, Pillemer S, Foulkes A, Shah A, Charney DS, Mathew SJ. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. The American Journal of Psychiatry. 170: 1134-42. PMID 23982301 DOI: 10.1176/appi.ajp.2013.13030392  0.92
2013 Murrough JW, Perez AM, Pillemer S, Stern J, Parides MK, aan het Rot M, Collins KA, Mathew SJ, Charney DS, Iosifescu DV. Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biological Psychiatry. 74: 250-6. PMID 22840761 DOI: 10.1016/j.biopsych.2012.06.022  0.92
2012 Kellner CH, Greenberg RM, Murrough JW, Bryson EO, Briggs MC, Pasculli RM. ECT in treatment-resistant depression. The American Journal of Psychiatry. 169: 1238-44. PMID 23212054 DOI: 10.1176/appi.ajp.2012.12050648  0.92
2012 Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ. Neurobiology of resilience. Nature Neuroscience. 15: 1475-84. PMID 23064380 DOI: 10.1038/nn.3234  0.92
2012 Murrough JW, Charney DS. Is there anything really novel on the antidepressant horizon? Current Psychiatry Reports. 14: 643-9. PMID 22996298 DOI: 10.1007/s11920-012-0321-8  0.92
2012 Neumeister A, Normandin MD, Murrough JW, Henry S, Bailey CR, Luckenbaugh DA, Tuit K, Zheng MQ, Galatzer-Levy IR, Sinha R, Carson RE, Potenza MN, Huang Y. Positron emission tomography shows elevated cannabinoid CB1 receptor binding in men with alcohol dependence. Alcoholism, Clinical and Experimental Research. 36: 2104-9. PMID 22551199 DOI: 10.1111/j.1530-0277.2012.01815.x  0.92
2012 Mathew SJ, Shah A, Lapidus K, Clark C, Jarun N, Ostermeyer B, Murrough JW. Ketamine for treatment-resistant unipolar depression: current evidence. Cns Drugs. 26: 189-204. PMID 22303887 DOI: 10.2165/11599770-000000000-00000  0.44
2012 Shungu DC, Weiduschat N, Murrough JW, Mao X, Pillemer S, Dyke JP, Medow MS, Natelson BH, Stewart JM, Mathew SJ. Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology. Nmr in Biomedicine. 25: 1073-87. PMID 22281935 DOI: 10.1002/nbm.2772  0.92
2011 Murrough JW, Czermak C, Henry S, Nabulsi N, Gallezot JD, Gueorguieva R, Planeta-Wilson B, Krystal JH, Neumaier JF, Huang Y, Ding YS, Carson RE, Neumeister A. The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding. Archives of General Psychiatry. 68: 892-900. PMID 21893657 DOI: 10.1001/archgenpsychiatry.2011.91  0.92
2011 Murrough JW, Huang Y, Hu J, Henry S, Williams W, Gallezot JD, Bailey CR, Krystal JH, Carson RE, Neumeister A. Reduced amygdala serotonin transporter binding in posttraumatic stress disorder. Biological Psychiatry. 70: 1033-8. PMID 21855859 DOI: 10.1016/j.biopsych.2011.07.003  0.92
2011 Murrough JW, Iacoviello B, Neumeister A, Charney DS, Iosifescu DV. Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategies Neurobiology of Learning and Memory. 96: 553-563. PMID 21704176 DOI: 10.1016/j.nlm.2011.06.006  0.92
2011 Murrough JW, Perez AM, Mathew SJ, Charney DS. A case of sustained remission following an acute course of ketamine in treatment-resistant depression. The Journal of Clinical Psychiatry. 72: 414-5. PMID 21450159 DOI: 10.4088/JCP.10l06447blu  0.92
2011 Murrough JW, Charney DS. The serotonin transporter and emotionality: risk, resilience, and new therapeutic opportunities. Biological Psychiatry. 69: 510-2. PMID 21353836 DOI: 10.1016/j.biopsych.2011.01.019  0.92
2011 Mathew SJ, Vythilingam M, Murrough JW, Zarate CA, Feder A, Luckenbaugh DA, Kinkead B, Parides MK, Trist DG, Bani MS, Bettica PU, Ratti EM, Charney DS. A selective neurokinin-1 receptor antagonist in chronic PTSD: a randomized, double-blind, placebo-controlled, proof-of-concept trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 221-9. PMID 21194898 DOI: 10.1016/j.euroneuro.2010.11.012  0.92
2011 Murrough JW, Henry S, Hu J, Gallezot JD, Planeta-Wilson B, Neumaier JF, Neumeister A. Reduced ventral striatal/ventral pallidal serotonin1B receptor binding potential in major depressive disorder. Psychopharmacology. 213: 547-53. PMID 20480149 DOI: 10.1007/s00213-010-1881-0  0.92
2010 Murrough JW, Charney DS. Cracking the moody brain: lifting the mood with ketamine. Nature Medicine. 16: 1384-5. PMID 21135850 DOI: 10.1038/nm1210-1384  0.92
2010 Murrough JW, Mao X, Collins KA, Kelly C, Andrade G, Nestadt P, Levine SM, Mathew SJ, Shungu DC. Increased ventricular lactate in chronic fatigue syndrome measured by 1H MRS imaging at 3.0 T. II: comparison with major depressive disorder. Nmr in Biomedicine. 23: 643-50. PMID 20661876 DOI: 10.1002/nbm.1512  0.92
2010 aan het Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS, Mathew SJ. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression. Biological Psychiatry. 67: 139-45. PMID 19897179 DOI: 10.1016/j.biopsych.2009.08.038  0.92
2010 Mathew SJ, Murrough JW, aan het Rot M, Collins KA, Reich DL, Charney DS. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 71-82. PMID 19288975 DOI: 10.1017/S1461145709000169  0.92
2009 New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. A Functional Magnetic Resonance Imaging Study of Deliberate Emotion Regulation in Resilience and Posttraumatic Stress Disorder Biological Psychiatry. 66: 656-664. PMID 19589502 DOI: 10.1016/j.biopsych.2009.05.020  0.92
2009 Price RB, Shungu DC, Mao X, Nestadt P, Kelly C, Collins KA, Murrough JW, Charney DS, Mathew SJ. Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder. Biological Psychiatry. 65: 792-800. PMID 19058788 DOI: 10.1016/j.biopsych.2008.10.025  0.92
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