Carlos A. Zarate, M.D. - Publications

Affiliations: 
National Institute of Mental Health, Bethesda, MD, United States 
Area:
Depression, Ketamine

238 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Grunebaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, ... ... Zarate CA, et al. Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Translational Psychiatry. 9: 108. PMID 30837454 DOI: 10.1038/s41398-019-0442-5  0.48
2019 Reed JL, Nugent AC, Furey ML, Szczepanik JE, Evans JW, Zarate CA. Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 30826253 DOI: 10.1016/j.bpsc.2019.01.005  0.6
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/pnas.1816071116  0.36
2019 Ballard ED, Reed JL, Szczepanik J, Evans JW, Yarrington JS, Dickstein DP, Nock MK, Nugent AC, Zarate CA. Functional Imaging of the Implicit Association of the Self With Life and Death. Suicide & Life-Threatening Behavior. PMID 30761601 DOI: 10.1111/sltb.12543  0.92
2019 Park LT, Zarate CA. Depression in the Primary Care Setting. The New England Journal of Medicine. 380: 559-568. PMID 30726688 DOI: 10.1056/NEJMcp1712493  0.48
2019 Wilkinson ST, Farmer C, Ballard E, Mathew SJ, Grunebaum MF, Murrough JW, Sos P, Wang G, Gueorguieva R, Zarate CA. Impact of midazolam vs. saline on effect size estimates in controlled trials of ketamine as a rapid-acting antidepressant. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30653192 DOI: 10.1038/s41386-019-0317-8  0.48
2018 Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Gruenbaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, ... ... Zarate CA, et al. Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Translational Psychiatry. 8: 280. PMID 30552317 DOI: 10.1038/s41398-018-0311-7  0.48
2018 Nugent AC, Wills KE, Gilbert JR, Zarate CA. Synaptic potentiation and rapid antidepressant response to ketamine in treatment-resistant major depression: A replication study. Psychiatry Research. Neuroimaging. 283: 64-66. PMID 30551012 DOI: 10.1016/j.pscychresns.2018.09.001  0.6
2018 Kadriu B, Musazzi L, Henter ID, Graves M, Popoli M, Zarate CA. Glutamatergic Neurotransmission: Pathway to Developing Novel Rapid-Acting Antidepressant Treatments. The International Journal of Neuropsychopharmacology. PMID 30445512 DOI: 10.1093/ijnp/pyy094  0.36
2018 Duncan WC, Slonena EE, Hejazi NS, Brutsche N, Park LT, Henter ID, Ballard ED, Zarate CA. Are 24-hour motor activity patterns associated with continued rapid response to ketamine? Neuropsychiatric Disease and Treatment. 14: 2739-2748. PMID 30410340 DOI: 10.2147/NDT.S172089  0.92
2018 Saligan LN, Farmer C, Ballard ED, Kadriu B, Zarate CA. Disentangling the association of depression on the anti-fatigue effects of ketamine. Journal of Affective Disorders. 244: 42-45. PMID 30312839 DOI: 10.1016/j.jad.2018.10.089  0.92
2018 Park L, Furey M, Nugent AC, Farmer C, Ellis J, Szczepanik J, Lener MS, Zarate CA. Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder. The International Journal of Neuropsychopharmacology. PMID 30184133 DOI: 10.1093/ijnp/pyy051  0.6
2018 Moaddel R, Shardell M, Khadeer M, Lovett J, Kadriu B, Ravichandran S, Morris PJ, Yuan P, Thomas CJ, Gould TD, Ferrucci L, Zarate CA. Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects. Psychopharmacology. PMID 30116859 DOI: 10.1007/s00213-018-4992-7  0.36
2018 Ballard ED, Yarrington JS, Farmer CA, Richards E, Machado-Vieira R, Kadriu B, Niciu MJ, Yuan P, Park L, Zarate CA. Characterizing the course of suicidal ideation response to ketamine. Journal of Affective Disorders. 241: 86-93. PMID 30099268 DOI: 10.1016/j.jad.2018.07.077  0.92
2018 Reed JL, Nugent AC, Furey ML, Szczepanik JE, Evans JW, Zarate CA. Ketamine normalizes brain activity during emotionally valenced attentional processing in depression. Neuroimage. Clinical. 20: 92-101. PMID 30094160 DOI: 10.1016/j.nicl.2018.07.006  0.6
2018 Richards EM, Zanotti-Fregonara P, Fujita M, Newman L, Farmer C, Ballard ED, Machado-Vieira R, Yuan P, Niciu MJ, Lyoo CH, Henter ID, Salvadore G, Drevets WC, Kolb H, Innis RB, ... Zarate CA, et al. PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects. Ejnmmi Research. 8: 57. PMID 29971587 DOI: 10.1186/s13550-018-0401-9  0.92
2018 Evans JW, Lally N, An L, Li N, Nugent AC, Banerjee D, Snider SL, Shen J, Roiser JP, Zarate CA. 7T H-MRS in major depressive disorder: a Ketamine Treatment Study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29748628 DOI: 10.1038/s41386-018-0057-1  0.6
2018 Ballard ED, Zarate CA. Preventing suicide: A multicausal model requires multimodal research and intervention. Bipolar Disorders. PMID 29729077 DOI: 10.1111/bdi.12656  0.92
2018 Gilbert JR, Yarrington JS, Wills KE, Nugent AC, Zarate CA. Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling. The International Journal of Neuropsychopharmacology. PMID 29668918 DOI: 10.1093/ijnp/pyy041  0.6
2018 Kadriu B, Yuan S, Farmer C, Nugent AC, Lener MS, Niciu MJ, Park M, Yazdian A, Ballard ED, Henn FA, Henter ID, Park LT, Zarate CA. Clinical Trial of the Potassium Channel Activator Diazoxide for Major Depressive Disorder Halted Due to Intolerability. Journal of Clinical Psychopharmacology. PMID 29601316 DOI: 10.1097/JCP.0000000000000866  0.92
2018 Evans JW, Szczepanik J, Brutsché N, Park LT, Nugent AC, Zarate CA. Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration. Biological Psychiatry. PMID 29580569 DOI: 10.1016/j.biopsych.2018.01.027  0.6
2018 Niciu MJ, Shovestul BJ, Jaso BA, Farmer C, Luckenbaugh DA, Brutsche NE, Park LT, Ballard ED, Zarate CA. Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression. Journal of Affective Disorders. 232: 310-315. PMID 29501990 DOI: 10.1016/j.jad.2018.02.049  0.92
2018 Nugent AC, Ballard ED, Gould TD, Park LT, Moaddel R, Brutsche NE, Zarate CA. Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects. Molecular Psychiatry. PMID 29487402 DOI: 10.1038/s41380-018-0028-2  0.92
2018 Henter ID, de Sousa RT, Zarate CA. Glutamatergic Modulators in Depression. Harvard Review of Psychiatry. PMID 29465478 DOI: 10.1097/HRP.0000000000000183  0.32
2018 Ballard ED, Yarrington JS, Farmer CA, Lener MS, Kadriu B, Lally N, Williams D, Machado-Vieira R, Niciu MJ, Park L, Zarate CA. Parsing the heterogeneity of depression: An exploratory factor analysis across commonly used depression rating scales. Journal of Affective Disorders. 231: 51-57. PMID 29448238 DOI: 10.1016/j.jad.2018.01.027  0.92
2017 Nugent AC, Zarate CA. Using Neuroimaging to Decipher the Mechanism of Action of Ketamine: A Pathway to Novel Therapeutics? Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2: 549-551. PMID 29560906 DOI: 10.1016/j.bpsc.2017.08.006  0.6
2017 Niciu MJ, Iadarola ND, Banerjee D, Luckenbaugh DA, Park M, Lener M, Park L, Ionescu DF, Ballard ED, Brutsche NE, Akula N, McMahon FJ, Machado-Vieira R, Nugent AC, Zarate CA. The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder. Journal of Psychopharmacology (Oxford, England). 269881117732514. PMID 29039254 DOI: 10.1177/0269881117732514  0.92
2017 Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA, Sanacora G. The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis. The American Journal of Psychiatry. appiajp201717040472. PMID 28969441 DOI: 10.1176/appi.ajp.2017.17040472  0.92
2017 Duncan WC, Ballard ED, Zarate CA. Ketamine-Induced Glutamatergic Mechanisms of Sleep and Wakefulness: Insights for Developing Novel Treatments for Disturbed Sleep and Mood. Handbook of Experimental Pharmacology. PMID 28939975 DOI: 10.1007/164_2017_51  0.92
2017 Szczepanik JE, Furey ML, Nugent AC, Henter ID, Zarate CA, Lejuez CW. Altered interaction with environmental reinforcers in major depressive disorder: Relationship to anhedonia. Behaviour Research and Therapy. 97: 170-177. PMID 28806614 DOI: 10.1016/j.brat.2017.08.003  0.6
2017 Ballard ED, Snider SL, Nugent AC, Luckenbaugh DA, Park L, Zarate CA. Active suicidal ideation during clinical antidepressant trials. Psychiatry Research. 257: 303-308. PMID 28787656 DOI: 10.1016/j.psychres.2017.07.065  0.92
2017 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KSS, Fang Y, Huang XP, Mayo CL, Albuquerque EX, ... ... Zarate CA, et al. Zanos et al. reply. Nature. 546: E4-E5. PMID 28640272 DOI: 10.1038/nature22085  0.36
2017 Nugent AC, Miller FG, Henter ID, Zarate CA. The Ethics of Clinical Trials Research in Severe Mood Disorders. Bioethics. PMID 28503892 DOI: 10.1111/bioe.12349  0.6
2017 Ballard ED, Wills K, Lally N, Richards EM, Luckenbaugh DA, Walls T, Ameli R, Niciu MJ, Brutsche NE, Park L, Zarate CA. Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials. Journal of Affective Disorders. 218: 195-200. PMID 28477497 DOI: 10.1016/j.jad.2017.04.057  0.92
2017 Duncan WC, Slonena E, Hejazi NS, Brutsche N, Yu KC, Park L, Ballard ED, Zarate CA. Motor-Activity Markers of Circadian Timekeeping Are Related to Ketamine's Rapid Antidepressant Properties. Biological Psychiatry. PMID 28457485 DOI: 10.1016/j.biopsych.2017.03.011  0.92
2017 Park LT, Lener MS, Hopkins M, Iadorola N, Machado-Vieira R, Ballard E, Nugent A, Zarate CA. A Double-Blind, Placebo-Controlled, Pilot Study of Riluzole Monotherapy for Acute Bipolar Depression. Journal of Clinical Psychopharmacology. PMID 28338546 DOI: 10.1097/JCP.0000000000000693  0.48
2017 Pennybaker SJ, Luckenbaugh DA, Park LT, Marquardt CA, Zarate CA. Ketamine and Psychosis History: Antidepressant Efficacy and Psychotomimetic Effects Postinfusion. Biological Psychiatry. PMID 28262250 DOI: 10.1016/j.biopsych.2016.08.041  0.56
2017 Lener MS, Kadriu B, Zarate CA. Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression. Drugs. PMID 28194724 DOI: 10.1007/s40265-017-0702-8  0.4
2016 Vande Voort JL, Ballard ED, Luckenbaugh DA, Bernert RA, Richards EM, Niciu MJ, Park LT, Machado-Vieira R, Duncan WC, Zarate CA. Antisuicidal Response Following Ketamine Infusion Is Associated With Decreased Nighttime Wakefulness in Major Depressive Disorder and Bipolar Disorder. The Journal of Clinical Psychiatry. PMID 27929610 DOI: 10.4088/JCP.15m10440  0.92
2016 Lepow L, Luckenbaugh DA, Park L, Henter ID, Zarate CA. Case series: Antidepressant effects of low-affinity and low-trapping NMDA receptor antagonists did not predict response to ketamine in seven subjects. Journal of Psychiatric Research. 86: 55-57. PMID 27914292 DOI: 10.1016/j.jpsychires.2016.10.023  0.56
2016 Machado-Vieira R, Zanetti MV, Otaduy MC, De Sousa RT, Soeiro-de-Souza MG, Costa AC, Carvalho AF, Leite CC, Busatto GF, Zarate CA, Gattaz WF. Increased Brain Lactate During Depressive Episodes and Reversal Effects by Lithium Monotherapy in Drug-Naive Bipolar Disorder: A 3-T 1H-MRS Study. Journal of Clinical Psychopharmacology. PMID 27902528 DOI: 10.1097/JCP.0000000000000616  0.48
2016 Zarate CA, Machado-Vieira R. GSK-3: a key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput. Bipolar Disorders. PMID 27900801 DOI: 10.1111/bdi.12452  0.48
2016 Pennybaker SJ, Niciu MJ, Luckenbaugh DA, Zarate CA. Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion. Journal of Affective Disorders. PMID 27839782 DOI: 10.1016/j.jad.2016.10.026  0.56
2016 Bernert RA, Luckenbaugh DA, Duncan WC, Iwata NG, Ballard ED, Zarate CA. Sleep architecture parameters as a putative biomarker of suicidal ideation in treatment-resistant depression. Journal of Affective Disorders. 208: 309-315. PMID 27810712 DOI: 10.1016/j.jad.2016.08.050  0.92
2016 Henter ID, de Sousa RT, Gold PW, Brunoni AR, Zarate CA, Machado-Vieira R. Mood Therapeutics: Novel Pharmacological Approaches for Treating Depression. Expert Review of Clinical Pharmacology. PMID 27781556 DOI: 10.1080/17512433.2017.1253472  0.48
2016 Nugent AC, Luber B, Carver FW, Robinson SE, Coppola R, Zarate CA. Deriving frequency-dependent spatial patterns in MEG-derived resting state sensorimotor network: A novel multiband ICA technique. Human Brain Mapping. PMID 27770478 DOI: 10.1002/hbm.23417  0.6
2016 Park M, Newman LE, Gold PW, Luckenbaugh DA, Yuan P, Machado-Vieira R, Zarate CA. Change in cytokine levels is not associated with rapid antidepressant response to ketamine in treatment-resistant depression. Journal of Psychiatric Research. 84: 113-118. PMID 27718369 DOI: 10.1016/j.jpsychires.2016.09.025  0.48
2016 Berg HE, Ballard ED, Luckenbaugh DA, Nugent AC, Ionescu DF, Zarate CA. Recognition of emotional facial expressions in anxious and nonanxious depression. Comprehensive Psychiatry. 70: 1-8. PMID 27624417 DOI: 10.1016/j.comppsych.2016.06.007  0.48
2016 Machado-Vieira R, Luckenbaugh DA, Ballard ED, Henter ID, Tohen M, Suppes T, Zarate CA. Increased Activity or Energy as a Primary Criterion for the Diagnosis of Bipolar Mania in DSM-5: Findings From the STEP-BD Study. The American Journal of Psychiatry. appiajp201615091132. PMID 27523498 DOI: 10.1176/appi.ajp.2016.15091132  0.92
2016 de Sousa RT, Loch AA, Carvalho AF, Brunoni AR, Haddad MR, Henter ID, Zarate CA, Machado-Vieira R. Genetic Studies on the Tripartite Glutamate Synapse in the Pathophysiology and Therapeutics of Mood Disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27510426 DOI: 10.1038/npp.2016.149  0.48
2016 Lamers F, Cui L, Hickie IB, Roca C, Machado-Vieira R, Zarate CA, Merikangas KR. Familial aggregation and heritability of the melancholic and atypical subtypes of depression. Journal of Affective Disorders. 204: 241-246. PMID 27450632 DOI: 10.1016/j.jad.2016.06.040  0.48
2016 Lener MS, Niciu MJ, Ballard ED, Park M, Park LT, Nugent AC, Zarate CA. Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine. Biological Psychiatry. PMID 27449797 DOI: 10.1016/j.biopsych.2016.05.005  0.48
2016 Szczepanik J, Nugent AC, Drevets WC, Khanna A, Zarate CA, Furey ML. Amygdala response to explicit sad face stimuli at baseline predicts antidepressant treatment response to scopolamine in major depressive disorder. Psychiatry Research. 254: 67-73. PMID 27366831 DOI: 10.1016/j.pscychresns.2016.06.005  0.48
2016 Nugent AC, Robinson SE, Coppola R, Zarate CA. Preliminary differences in resting state MEG functional connectivity pre- and post-ketamine in major depressive disorder. Psychiatry Research. 254: 56-66. PMID 27362845 DOI: 10.1016/j.pscychresns.2016.06.006  0.6
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Zarate CA, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/j.biopsych.2016.05.004  0.48
2016 Ballard ED, Vande Voort JL, Bernert RA, Luckenbaugh DA, Richards EM, Niciu MJ, Furey ML, Duncan WC, Zarate CA. Nocturnal Wakefulness Is Associated With Next-Day Suicidal Ideation in Major Depressive Disorder and Bipolar Disorder. The Journal of Clinical Psychiatry. 77: 825-831. PMID 27337418 DOI: 10.4088/JCP.15m09943  0.48
2016 Ballard ED, Vande Voort JL, Luckenbaugh DA, Machado-Vieira R, Tohen M, Zarate CA. Acute risk factors for suicide attempts and death: prospective findings from the STEP-BD study. Bipolar Disorders. PMID 27233466 DOI: 10.1111/bdi.12397  0.48
2016 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, ... ... Zarate CA, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. PMID 27144355 DOI: 10.1038/nature17998  0.48
2016 Jaso BA, Niciu MJ, Iadarola ND, Lally N, Richards EM, Park M, Ballard ED, Nugent AC, Machado-Vieira R, Zarate CA. THERAPEUTIC MODULATION OF GLUTAMATE RECEPTORS IN MAJOR DEPRESSIVE DISORDER. Current Neuropharmacology. PMID 26997505  0.92
2016 Nugent AC, Iadarola ND, Miller FG, Luckenbaugh DA, Zarate CA. Safety of research into severe and treatment-resistant mood disorders: analysis of outcome data from 12 years of clinical trials at the US National Institute of Mental Health. The Lancet. Psychiatry. PMID 26971192 DOI: 10.1016/S2215-0366(16)00006-7  0.48
2016 Saligan LN, Luckenbaugh DA, Slonena EE, Machado-Vieira R, Zarate CA. An assessment of the anti-fatigue effects of ketamine from a double-blind, placebo-controlled, crossover study in bipolar disorder. Journal of Affective Disorders. 194: 115-119. PMID 26807672 DOI: 10.1016/j.jad.2016.01.009  0.48
2016 Richards EM, Mathews DC, Luckenbaugh DA, Ionescu DF, Machado-Vieira R, Niciu MJ, Duncan WC, Nolan NM, Franco-Chaves JA, Hudzik T, Maciag C, Li S, Cross A, Smith MA, Zarate CA. A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression. Psychopharmacology. PMID 26728893 DOI: 10.1007/s00213-015-4195-4  0.48
2015 Park M, Niciu MJ, Zarate CA. Novel Glutamatergic Treatments for Severe Mood Disorders. Current Behavioral Neuroscience Reports. 2: 198-208. PMID 26824031 DOI: 10.1007/s40473-015-0050-5  0.48
2015 Machado-Vieira R, Henter ID, Zarate CA. New Targets for Rapid Antidepressant Action. Progress in Neurobiology. PMID 26724279 DOI: 10.1016/j.pneurobio.2015.12.001  0.48
2015 Zarate CA, Niciu MJ. Ketamine for depression: evidence, challenges and promise. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 14: 348-50. PMID 26407791 DOI: 10.1002/wps.20269  0.48
2015 de Sousa RT, Streck EL, Forlenza OV, Brunoni AR, Zanetti MV, Ferreira GK, Diniz BS, Portela LV, Carvalho AF, Zarate CA, Gattaz WF, Machado-Vieira R. Regulation of leukocyte tricarboxylic acid cycle in drug-naïve Bipolar Disorder. Neuroscience Letters. 605: 65-8. PMID 26297865 DOI: 10.1016/j.neulet.2015.08.022  0.48
2015 Zanos P, Piantadosi SC, Wu HQ, Pribut HJ, Dell MJ, Can A, Snodgrass HR, Zarate CA, Schwarcz R, Gould TD. The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition. The Journal of Pharmacology and Experimental Therapeutics. 355: 76-85. PMID 26265321 DOI: 10.1124/jpet.115.225664  0.48
2015 Saligan LN, Luckenbaugh DA, Slonena EE, Machado-Vieira R, Zarate CA. Development of a clinician-administered National Institutes of Health-Brief Fatigue Inventory: A measure of fatigue in the context of depressive disorders. Journal of Psychiatric Research. 68: 99-105. PMID 26228407 DOI: 10.1016/j.jpsychires.2015.06.012  0.56
2015 Ballard ED, Luckenbaugh DA, Richards EM, Walls TL, Brutsché NE, Ameli R, Niciu MJ, Vande Voort JL, Zarate CA. Assessing measures of suicidal ideation in clinical trials with a rapid-acting antidepressant. Journal of Psychiatric Research. 68: 68-73. PMID 26228403 DOI: 10.1016/j.jpsychires.2015.06.003  0.92
2015 Schaffer A, Isometsä ET, Azorin JM, Cassidy F, Goldstein T, Rihmer Z, Sinyor M, Tondo L, Moreno DH, Turecki G, Reis C, Kessing LV, Ha K, Weizman A, Beautrais A, ... ... Zarate CA, et al. A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. The Australian and New Zealand Journal of Psychiatry. PMID 26175498 DOI: 10.1177/0004867415594428  0.48
2015 Xu AJ, Niciu MJ, Lundin NB, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Machado-Vieira R, Zarate CA. Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression. Neural Plasticity. 2015: 858251. PMID 26137324 DOI: 10.1155/2015/858251  0.48
2015 Lally N, An L, Banerjee D, Niciu MJ, Luckenbaugh DA, Richards EM, Roiser JP, Shen J, Zarate CA, Nugent AC. Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation. Journal of Magnetic Resonance Imaging : Jmri. PMID 26059603 DOI: 10.1002/jmri.24970  0.48
2015 Zarate CA, Machado-Vieira R. Potential Pathways Involved in the Rapid Antidepressant Effects of Nitrous Oxide. Biological Psychiatry. 78: 2-4. PMID 26051637 DOI: 10.1016/j.biopsych.2015.04.007  0.48
2015 Nugent AC, Robinson SE, Coppola R, Furey ML, Zarate CA. Group differences in MEG-ICA derived resting state networks: Application to major depressive disorder. Neuroimage. 118: 1-12. PMID 26032890 DOI: 10.1016/j.neuroimage.2015.05.051  0.48
2015 Iadarola ND, Niciu MJ, Richards EM, Vande Voort JL, Ballard ED, Lundin NB, Nugent AC, Machado-Vieira R, Zarate CA. Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review. Therapeutic Advances in Chronic Disease. 6: 97-114. PMID 25954495 DOI: 10.1177/2040622315579059  0.48
2015 Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA. Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25820840 DOI: 10.1093/ijnp/pyv028  0.6
2015 Machado-Vieira R, Zanetti MV, Teixeira AL, Uno M, Valiengo LL, Soeiro-de-Souza MG, Oba-Shinjo SM, de Sousa RT, Zarate CA, Gattaz WF, Marie SK. Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 468-73. PMID 25726893 DOI: 10.1016/j.euroneuro.2015.02.002  0.48
2015 Lally N, Nugent AC, Luckenbaugh DA, Niciu MJ, Roiser JP, Zarate CA. Neural correlates of change in major depressive disorder anhedonia following open-label ketamine. Journal of Psychopharmacology (Oxford, England). 29: 596-607. PMID 25691504 DOI: 10.1177/0269881114568041  0.48
2015 Ionescu DF, Nugent AC, Luckenbaugh DA, Niciu MJ, Richards EM, Zarate CA, Furey ML. Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography. Acta Neuropsychiatrica. 27: 143-52. PMID 25600154 DOI: 10.1017/neu.2014.46  0.48
2015 Luckenbaugh DA, Ameli R, Brutsche NE, Zarate CA. Rating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales. Journal of Psychiatric Research. 61: 40-5. PMID 25592045 DOI: 10.1016/j.jpsychires.2014.12.015  0.56
2015 Teixeira AL, de Souza RT, Zanetti MV, Brunoni AR, Busatto GF, Zarate CA, Gattaz WF, Machado-Vieira R. Increased plasma levels of soluble TNF receptors 1 and 2 in bipolar depression and impact of lithium treatment. Human Psychopharmacology. 30: 52-6. PMID 25572309 DOI: 10.1002/hup.2450  0.48
2015 Nugent AC, Martinez A, D'Alfonso A, Zarate CA, Theodore WH. The relationship between glucose metabolism, resting-state fMRI BOLD signal, and GABAA-binding potential: a preliminary study in healthy subjects and those with temporal lobe epilepsy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 583-91. PMID 25564232 DOI: 10.1038/jcbfm.2014.228  0.48
2015 Monteggia LM, Zarate C. Antidepressant actions of ketamine: from molecular mechanisms to clinical practice. Current Opinion in Neurobiology. 30: 139-43. PMID 25562451 DOI: 10.1016/j.conb.2014.12.004  0.48
2015 Ballard ED, Lally N, Nugent AC, Furey ML, Luckenbaugh DA, Zarate CA. Neural correlates of suicidal ideation and its reduction in depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25550331 DOI: 10.1093/ijnp/pyu069  0.92
2015 Ortiz R, Ulrich H, Zarate CA, Machado-Vieira R. Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 57: 117-31. PMID 25445063 DOI: 10.1016/j.pnpbp.2014.10.016  0.48
2015 Ionescu DF, Luckenbaugh DA, Niciu MJ, Richards EM, Zarate CA. A single infusion of ketamine improves depression scores in patients with anxious bipolar depression. Bipolar Disorders. 17: 438-43. PMID 25400146 DOI: 10.1111/bdi.12277  0.48
2015 Schaffer A, Isometsä ET, Tondo L, H Moreno D, Turecki G, Reis C, Cassidy F, Sinyor M, Azorin JM, Kessing LV, Ha K, Goldstein T, Weizman A, Beautrais A, Chou YH, ... ... Zarate CA, et al. International Society for Bipolar Disorders Task Force on Suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disorders. 17: 1-16. PMID 25329791 DOI: 10.1111/bdi.12271  0.48
2015 Brunoni AR, Machado-Vieira R, Zarate CA, Vieira EL, Valiengo L, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. Assessment of non-BDNF neurotrophins and GDNF levels after depression treatment with sertraline and transcranial direct current stimulation in a factorial, randomized, sham-controlled trial (SELECT-TDCS): an exploratory analysis. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 56: 91-6. PMID 25172025 DOI: 10.1016/j.pnpbp.2014.08.009  0.48
2015 Moaddel R, Luckenbaugh DA, Xie Y, Villaseñor A, Brutsche NE, Machado-Vieira R, Ramamoorthy A, Lorenzo MP, Garcia A, Bernier M, Torjman MC, Barbas C, Zarate CA, Wainer IW. D-serine plasma concentration is a potential biomarker of (R, S)-ketamine antidepressant response in subjects with treatment-resistant depression Psychopharmacology. 232: 399-409. PMID 25056852 DOI: 10.1007/s00213-014-3669-0  0.48
2015 Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA. Pretreatment differences in BOLD response to emotional faces correlate with Antidepress ant response to scopolamine International Journal of Neuropsychopharmacology. 18: 1-10. DOI: 10.1093/ijnp/pyv028  0.48
2015 Ballard ED, Lally N, Nugent AC, Furey ML, Luckenbaugh DA, Zarate CA. Neural correlates of suicidal ideation and its reduction in depression International Journal of Neuropsychopharmacology. 18. DOI: 10.1093/ijnp/pyu069  0.48
2015 de Sousa RT, Streck EL, Forlenza OV, Brunoni AR, Zanetti MV, Ferreira GK, Diniz BS, Portela LV, Carvalho AF, Zarate CA, Gattaz WF, Machado-Vieira R. Regulation of leukocyte tricarboxylic acid cycle in drug-naïve Bipolar Disorder Neuroscience Letters. 605: 65-68. DOI: 10.1016/j.neulet.2015.08.022  0.48
2015 Saligan LN, Luckenbaugh DA, Slonena EE, Machado-Vieira R, Zarate CA. Development of a clinician-administered National Institutes of Health-Brief Fatigue Inventory: A measure of fatigue in the context of depressive disorders Journal of Psychiatric Research. 68: 99-105. DOI: 10.1016/j.jpsychires.2015.06.012  0.48
2015 Ballard ED, Luckenbaugh DA, Richards EM, Walls TL, Brutsché NE, Ameli R, Niciu MJ, Vande Voort JL, Zarate CA. Assessing measures of suicidal ideation in clinical trials with arapid-acting antidepressant Journal of Psychiatric Research. 68: 68-73. DOI: 10.1016/j.jpsychires.2015.06.003  0.48
2015 Luckenbaugh DA, Ameli R, Brutsche NE, Zarate CA. Rating depression over brief time intervals with the Hamilton Depression Rating Scale: Standard vs. abbreviated scales Journal of Psychiatric Research. 61: 40-45. DOI: 10.1016/j.jpsychires.2014.12.015  0.48
2014 Niciu MJ, Mathews DC, Ionescu DF, Richards EM, Furey ML, Yuan P, Nugent AC, Henter ID, Machado-Vieira R, Zarate CA. Biomarkers in mood disorders research: developing new and improved therapeutics. Revista De Psiquiatria Clinica. 41: 131-134. PMID 26082563  0.6
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Furey ML, Zarate CA. Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25539512 DOI: 10.1093/ijnp/pyu039  0.48
2014 Ortiz R, Niciu MJ, Lukkahati N, Saligan LN, Nugent AC, Luckenbaugh DA, Machado-Vieira R, Zarate CA. Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression. Journal of Affective Disorders. 172: 307-311. PMID 25451430 DOI: 10.1016/j.jad.2014.09.015  0.48
2014 Singh NS, Zarate CA, Moaddel R, Bernier M, Wainer IW. What is hydroxynorketamine and what can it bring to neurotherapeutics? Expert Review of Neurotherapeutics. 14: 1239-42. PMID 25331415 DOI: 10.1586/14737175.2014.971760  0.48
2014 Ionescu DF, Niciu MJ, Richards EM, Zarate CA. Pharmacologic treatment of dimensional anxious depression: a review. The Primary Care Companion For Cns Disorders. 16. PMID 25317369 DOI: 10.4088/PCC.13r01621  0.48
2014 Lally N, Nugent AC, Luckenbaugh DA, Ameli R, Roiser JP, Zarate CA. Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression. Translational Psychiatry. 4: e469. PMID 25313512 DOI: 10.1038/tp.2014.105  0.6
2014 Ionescu DF, Luckenbaugh DA, Niciu MJ, Richards EM, Slonena EE, Vande Voort JL, Brutsche NE, Zarate CA. Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine. The Journal of Clinical Psychiatry. 75: e932-8. PMID 25295436 DOI: 10.4088/JCP.14m09049  0.48
2014 Ballard ED, Ionescu DF, Vande Voort JL, Niciu MJ, Richards EM, Luckenbaugh DA, Brutsché NE, Ameli R, Furey ML, Zarate CA. Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety. Journal of Psychiatric Research. 58: 161-6. PMID 25169854 DOI: 10.1016/j.jpsychires.2014.07.027  0.48
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Furey ML, Zarate CA. Riluzole likely lacks antidepressant efficacy in ketamine non-responders. Journal of Psychiatric Research. 58: 197-9. PMID 25139008 DOI: 10.1016/j.jpsychires.2014.07.022  0.48
2014 de Sousa RT, Machado-Vieira R, Zarate CA, Manji HK. Targeting mitochondrially mediated plasticity to develop improved therapeutics for bipolar disorder. Expert Opinion On Therapeutic Targets. 18: 1131-47. PMID 25056514 DOI: 10.1517/14728222.2014.940893  0.48
2014 Ameli R, Luckenbaugh DA, Gould NF, Holmes MK, Lally N, Ballard ED, Zarate CA. SHAPS-C: the Snaith-Hamilton pleasure scale modified for clinician administration. Peerj. 2: e429. PMID 25024906 DOI: 10.7717/peerj.429  0.48
2014 Lundin NB, Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Brutsche NE, Machado-Vieira R, Zarate CA. Baseline vitamin B12 and folate levels do not predict improvement in depression after a single infusion of ketamine. Pharmacopsychiatry. 47: 141-4. PMID 24955551 DOI: 10.1055/s-0034-1377042  0.48
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Guevara S, Machado-Vieira R, Richards EM, Brutsche NE, Nolan NM, Zarate CA. Clinical predictors of ketamine response in treatment-resistant major depression. The Journal of Clinical Psychiatry. 75: e417-23. PMID 24922494 DOI: 10.4088/JCP.13m08698  0.48
2014 de Sousa RT, Zanetti MV, Busatto GF, Mouro MG, Zarate CA, Gattaz WF, Higa EM, Machado-Vieira R. Lithium increases nitric oxide levels in subjects with bipolar disorder during depressive episodes. Journal of Psychiatric Research. 55: 96-100. PMID 24768108 DOI: 10.1016/j.jpsychires.2014.03.023  0.48
2014 Ellis JS, Zarate CA, Luckenbaugh DA, Furey ML. Antidepressant treatment history as a predictor of response to scopolamine: Clinical implications Journal of Affective Disorders. 162: 39-42. PMID 24767003 DOI: 10.1016/j.jad.2014.03.010  0.48
2014 Ballard ED, Ionescu DF, Vande Voort JL, Slonena EE, Franco-Chaves JA, Zarate CA, Grillon C. Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt. Journal of Affective Disorders. 162: 34-8. PMID 24767002 DOI: 10.1016/j.jad.2014.03.027  0.48
2014 Brunoni AR, Machado-Vieira R, Zarate CA, Vieira EL, Vanderhasselt MA, Nitsche MA, Valiengo L, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: results from a factorial, randomized, sham-controlled trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1144-51. PMID 24702987 DOI: 10.1016/j.euroneuro.2014.03.006  0.48
2014 Umhau JC, Schwandt M, Solomon MG, Yuan P, Nugent A, Zarate CA, Drevets WC, Hall SD, George DT, Heilig M. Cerebrospinal fluid monocyte chemoattractant protein-1 in alcoholics: support for a neuroinflammatory model of chronic alcoholism. Alcoholism, Clinical and Experimental Research. 38: 1301-6. PMID 24689518 DOI: 10.1111/acer.12367  0.48
2014 Villaseñor A, Ramamoorthy A, Silva Dos Santos M, Lorenzo MP, Laje G, Zarate C, Barbas C, Wainer IW. A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: Evidence for a response-related difference in mitochondrial networks British Journal of Pharmacology. 171: 2230-2242. PMID 24684390 DOI: 10.1111/bph.12494  0.48
2014 Luckenbaugh DA, Niciu MJ, Ionescu DF, Nolan NM, Richards EM, Brutsche NE, Guevara S, Zarate CA. Do the dissociative side effects of ketamine mediate its antidepressant effects? Journal of Affective Disorders. 159: 56-61. PMID 24679390 DOI: 10.1016/j.jad.2014.02.017  0.56
2014 Svenningsson P, Berg L, Matthews D, Ionescu DF, Richards EM, Niciu MJ, Malinger A, Toups M, Manji H, Trivedi MH, Zarate CA, Greengard P. Preliminary evidence that early reduction in p11 levels in natural killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram. Molecular Psychiatry. 19: 962-4. PMID 24614495 DOI: 10.1038/mp.2014.13  0.48
2014 Suppes T, Frank E, DePaulo JR, Davis L, Zarate CA, Angst J, Fawcett J. Letter to the editor in response to 2012 article by Frances and Jones. Bipolar Disorders. 16: 214-5. PMID 24597757 DOI: 10.1111/bdi.12176  0.48
2014 Lyoo CH, Zanotti-Fregonara P, Zoghbi SS, Liow JS, Xu R, Pike VW, Zarate CA, Fujita M, Innis RB. Image-derived input function derived from a supervised clustering algorithm: Methodology and validation in a clinical protocol using [ 11C](R)-rolipram Plos One. 9. PMID 24586526 DOI: 10.1371/journal.pone.0089101  0.48
2014 Deveney CM, Brotman MA, Thomas LA, Hinton KE, Muhrer EM, Reynolds RC, Adleman NE, Zarate CA, Pine DS, Leibenluft E. Neural response during explicit and implicit face processing varies developmentally in bipolar disorder. Social Cognitive and Affective Neuroscience. 9: 1984-92. PMID 24493839 DOI: 10.1093/scan/nsu014  0.48
2014 Niciu MJ, Henter ID, Luckenbaugh DA, Zarate CA, Charney DS. Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds. Annual Review of Pharmacology and Toxicology. 54: 119-39. PMID 24392693 DOI: 10.1146/annurev-pharmtox-011613-135950  0.48
2014 Grant PJ, Joseph LA, Farmer CA, Luckenbaugh DA, Lougee LC, Zarate CA, Swedo SE. 12-week, placebo-controlled trial of add-on riluzole in the treatment of childhood-onset obsessive-compulsive disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1453-9. PMID 24356715 DOI: 10.1038/npp.2013.343  0.48
2014 Niciu MJ, Mathews DC, Nugent AC, Ionescu DF, Furey ML, Richards EM, Machado-Vieira R, Zarate CA. Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants. Depression and Anxiety. 31: 297-307. PMID 24353110 DOI: 10.1002/da.22224  0.48
2014 de Sousa RT, Zarate CA, Zanetti MV, Costa AC, Talib LL, Gattaz WF, Machado-Vieira R. Oxidative stress in early stage Bipolar Disorder and the association with response to lithium. Journal of Psychiatric Research. 50: 36-41. PMID 24332923 DOI: 10.1016/j.jpsychires.2013.11.011  0.48
2014 Niciu MJ, Ionescu DF, Richards EM, Zarate CA. Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 907-24. PMID 24318540 DOI: 10.1007/s00702-013-1130-x  0.48
2014 Brunoni AR, Machado-Vieira R, Zarate CA, Valiengo L, Vieira EL, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. Cytokines plasma levels during antidepressant treatment with sertraline and transcranial direct current stimulation (tDCS): results from a factorial, randomized, controlled trial. Psychopharmacology. 231: 1315-23. PMID 24150249 DOI: 10.1007/s00213-013-3322-3  0.48
2014 Merikangas KR, Cui L, Heaton L, Nakamura E, Roca C, Ding J, Qin H, Guo W, Shugart YY, Yao-Shugart Y, Zarate C, Angst J. Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Molecular Psychiatry. 19: 214-9. PMID 24126930 DOI: 10.1038/mp.2013.116  0.48
2014 Nugent AC, Diazgranados N, Carlson PJ, Ibrahim L, Luckenbaugh DA, Brutsche N, Herscovitch P, Drevets WC, Zarate CA. Neural correlates of rapid antidepressant response to ketamine in bipolar disorder Bipolar Disorders. 16: 119-128. PMID 24103187 DOI: 10.1111/bdi.12118  0.48
2014 Niciu MJ, Henter ID, Sanacora G, Zarate CA. Glial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity? The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 15: 2-16. PMID 24024876 DOI: 10.3109/15622975.2013.829585  0.48
2014 Machado-Vieira R, Soeiro-De-Souza MG, Richards EM, Teixeira AL, Zarate CA. Multiple levels of impaired neural plasticity and cellular resilience in bipolar disorder: developing treatments using an integrated translational approach. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 15: 84-95. PMID 23998912 DOI: 10.3109/15622975.2013.830775  0.48
2014 Brotman MA, Tseng WL, Olsavsky AK, Fromm SJ, Muhrer EJ, Rutenberg JG, Deveney CM, Adleman NE, Zarate CA, Pine DS, Leibenluft E. Fronto-limbic-striatal dysfunction in pediatric and adult patients with bipolar disorder: impact of face emotion and attentional demands. Psychological Medicine. 44: 1639-51. PMID 23930595 DOI: 10.1017/S003329171300202X  0.48
2014 Niciu MJ, Mathews DC, Ionescu DF, Richards EM, Furey ML, Yuan P, Nugent AC, Henter ID, Machado-Vieira R, Zarate CA. Biomarkers in mood disorders research: Developing new and improved therapeutics Revista De Psiquiatria Clinica. 41: 131-134. DOI: 10.1590/0101-60830000000027  0.48
2014 Scorza FA, Zarate CA. Schizophrenia: If death occurs without warning, what we should propose for the near future? | Esquizofrenia: Se a morte acontece sem aviso prévio, o que devemos propor para o futuro próximo? Revista De Psiquiatria Clinica. 41: 112-113. DOI: 10.1590/0101-60830000000022  0.48
2014 De Sousa RT, MacHado-Vieira R, Zarate CA, Manji HK. Targeting mitochondrially mediated plasticity to develop improved therapeutics for bipolar disorder Expert Opinion On Therapeutic Targets. 18: 1131-1147. DOI: 10.1517/14728222.2014.940893  0.48
2014 Luckenbaugh DA, Niciu MJ, Ionescu DF, Nolan NM, Richards EM, Brutsche NE, Guevara S, Zarate CA. Do the dissociative side effects of ketamine mediate its antidepressant effects? Journal of Affective Disorders. 159: 56-61. DOI: 10.1016/j.jad.2014.02.017Brief  0.48
2014 Griffiths JJ, Zarate CA, Rasimas JJ. Existing and novel biological therapeutics in suicide prevention American Journal of Preventive Medicine. 47: S195-S203. DOI: 10.1016/j.amepre.2014.06.012  0.48
2014 Ballard ED, Richards EM, Ionescu DF, Niciu MJ, Voort JV, Zarate CA. Experimental pharmacologic approaches for the reduction of suicidal ideation and behavior Suicide: Phenomenology and Neurobiology. 209-221. DOI: 10.1007/978-3-319-09964-4_12  0.48
2013 Mathews DC, Richards EM, Niciu MJ, Ionescu DF, Rasimas JJ, Zarate CA. NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER. Translational Neuroscience. 4. PMID 24294519 DOI: 10.2478/s13380-013-0120-7  0.48
2013 Machado-Vieira R, Zarate CA. Next-generation strategies in animal model research to translate preclinical discoveries into better treatments for circuit-centered psychiatric dimensions Revista Brasileira De Psiquiatria. 35: S75-S76. PMID 24271228 DOI: 10.1590/1516-4446-2013-1132  0.48
2013 Savitz J, Nugent AC, Bellgowan PS, Wright N, Tinsley R, Zarate CA, Herscovitch P, Drevets WC. Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study. Neuroimage. Clinical. 2: 341-55. PMID 24179788 DOI: 10.1016/j.nicl.2013.02.004  0.48
2013 Furey ML, Zarate CA. Pulsed intravenous administration of scopolamine produces rapid antidepressant effects and modest side effects Journal of Clinical Psychiatry. 74: 850-851. PMID 24021505 DOI: 10.4088/JCP.13ac08584  0.48
2013 Weathers J, Brotman MA, Deveney CM, Kim P, Zarate C, Fromm S, Pine D, Leibenluft E. A developmental study on the neural circuitry mediating response flexibility in bipolar disorder. Psychiatry Research. 214: 56-65. PMID 23958598 DOI: 10.1016/j.pscychresns.2013.05.002  0.48
2013 Grillon C, Franco-Chaves JA, Mateus CF, Ionescu DF, Zarate CA. Major depression is not associated with blunting of aversive responses; evidence for enhanced anxious anticipation. Plos One. 8: e70969. PMID 23951057 DOI: 10.1371/journal.pone.0070969  0.48
2013 Duncan WC, Zarate CA. Ketamine, sleep, and depression: Current status and new questions Current Psychiatry Reports. 15. PMID 23949569 DOI: 10.1007/s11920-013-0394-z  0.48
2013 Nugent AC, Carlson PJ, Bain EE, Eckelman W, Herscovitch P, Manji H, Zarate CA, Drevets WC. Mood stabilizer treatment increases serotonin type 1A receptor binding in bipolar depression Journal of Psychopharmacology. 27: 894-902. PMID 23926239 DOI: 10.1177/0269881113499204  0.48
2013 Zarate C, Duman RS, Liu G, Sartori S, Quiroz J, Murck H. New paradigms for treatment-resistant depression. Annals of the New York Academy of Sciences. 1292: 21-31. PMID 23876043 DOI: 10.1111/nyas.12223  0.48
2013 Nugent AC, Davis RM, Zarate CA, Drevets WC. Reduced thalamic volumes in major depressive disorder. Psychiatry Research. 213: 179-85. PMID 23850106 DOI: 10.1016/j.pscychresns.2013.05.004  0.6
2013 Mathews DC, Zarate CA. Current status of ketamine and related compounds for depression. The Journal of Clinical Psychiatry. 74: 516-7. PMID 23759454 DOI: 10.4088/JCP.13ac08382  0.48
2013 Niciu MJ, Luckenbaugh DA, Ionescu DF, Mathews DC, Richards EM, Zarate CA. Subanesthetic dose ketamine does not induce an affective switch in three independent samples of treatment-resistant major depression. Biological Psychiatry. 74: e23-4. PMID 23726512 DOI: 10.1016/j.biopsych.2013.01.038  0.48
2013 Zarate CA. New insights into the neurobiology, diagnosis, and treatment of mood disorders Cns Spectrums. 18: 228-230. PMID 23692663 DOI: 10.1017/S1092852913000254  0.48
2013 Martinowich K, Jimenez DV, Zarate CA, Manji HK. Rapid antidepressant effects: moving right along. Molecular Psychiatry. 18: 856-63. PMID 23689537 DOI: 10.1038/mp.2013.55  0.48
2013 Müller HK, Wegener G, Liebenberg N, Zarate CA, Popoli M, Elfving B. Ketamine regulates the presynaptic release machinery in the hippocampus Journal of Psychiatric Research. 47: 892-899. PMID 23548331 DOI: 10.1016/j.jpsychires.2013.03.008  0.48
2013 Adleman NE, Kayser RR, Olsavsky AK, Bones BL, Muhrer EJ, Fromm SJ, Pine DS, Zarate C, Leibenluft E, Brotman MA. Abnormal fusiform activation during emotional-face encoding assessed with functional magnetic resonance imaging. Psychiatry Research. 212: 161-3. PMID 23541333 DOI: 10.1016/j.pscychresns.2013.01.006  0.48
2013 Carlson PJ, Diazgranados N, Nugent AC, Ibrahim L, Luckenbaugh DA, Brutsche N, Herscovitch P, Manji HK, Zarate CA, Drevets WC. Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: A preliminary positron emission tomography study Biological Psychiatry. 73: 1213-1221. PMID 23540908 DOI: 10.1016/j.biopsych.2013.02.008  0.48
2013 Franco-Chaves JA, Mateus CF, Luckenbaugh DA, Martinez PE, Mallinger AG, Zarate CA. Combining a dopamine agonist and selective serotonin reuptake inhibitor for the treatment of depression: a double-blind, randomized pilot study. Journal of Affective Disorders. 149: 319-25. PMID 23517885 DOI: 10.1016/j.jad.2013.02.003  0.48
2013 Ionescu DF, Niciu MJ, Henter ID, Zarate CA. Defining anxious depression: a review of the literature. Cns Spectrums. 18: 252-60. PMID 23507190 DOI: 10.1017/S1092852913000114  0.48
2013 Ionescu DF, Niciu MJ, Mathews DC, Richards EM, Zarate CA. Neurobiology of anxious depression: a review. Depression and Anxiety. 30: 374-85. PMID 23495126 DOI: 10.1002/da.22095  0.48
2013 Niciu MJ, Ionescu DF, Mathews DC, Richards EM, Zarate CA. Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder. Cns Spectrums. 18: 242-51. PMID 23472710 DOI: 10.1017/S1092852913000138  0.48
2013 Niciu MJ, Ionescu DF, Mathews DC, Richards EM, Zarate CA. Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part I: major depressive disorder. Cns Spectrums. 18: 231-41. PMID 23462230 DOI: 10.1017/S1092852913000059  0.48
2013 Nugent AC, Bain EE, Carlson PJ, Neumeister A, Bonne O, Carson RE, Eckelman W, Herscovitch P, Zarate CA, Charney DS, Drevets WC. Reduced post-synaptic serotonin type 1A receptor binding in bipolar depression. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 822-9. PMID 23434290 DOI: 10.1016/j.euroneuro.2012.11.005  0.48
2013 Zarate CA, Mathews DC, Furey ML. Human biomarkers of rapid antidepressant effects Biological Psychiatry. 73: 1142-1155. PMID 23374639 DOI: 10.1016/j.biopsych.2012.11.031  0.48
2013 Furey ML, Drevets WC, Hoffman EM, Frankel E, Speer AM, Zarate CA. Potential of pretreatment neural activity in the visual cortex during emotional processing to predict treatment response to scopolamine in major depressive disorder. Jama Psychiatry. 70: 280-90. PMID 23364679 DOI: 10.1001/2013.jamapsychiatry.60  0.48
2013 Zeng MC, Niciu MJ, Luckenbaugh DA, Ionescu DF, Mathews DC, Richards EM, Franco-Chaves J, Brutsche NE, Zarate CA. Acute stress symptoms do not worsen in posttraumatic stress disorder and abuse with a single subanesthetic dose of ketamine. Biological Psychiatry. 73: e37-8. PMID 23245747 DOI: 10.1016/j.biopsych.2012.10.017  0.48
2013 Zarate CA, Mathews D, Ibrahim L, Chaves JF, Marquardt C, Ukoh I, Jolkovsky L, Brutsche NE, Smith MA, Luckenbaugh DA. A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression. Biological Psychiatry. 74: 257-64. PMID 23206319 DOI: 10.1016/j.biopsych.2012.10.019  0.48
2013 Drevets WC, Zarate CA, Furey ML. Antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine: A review Biological Psychiatry. 73: 1156-1163. PMID 23200525 DOI: 10.1016/j.biopsych.2012.09.031  0.48
2013 Moaddel R, Abdrakhmanova G, Kozak J, Jozwiak K, Toll L, Jimenez L, Rosenberg A, Tran T, Xiao Y, Zarate CA, Wainer IW. Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors. European Journal of Pharmacology. 698: 228-34. PMID 23183107 DOI: 10.1016/j.ejphar.2012.11.023  0.48
2013 Soeiro-de-Souza MG, Salvadore G, Moreno RA, Otaduy MC, Chaim KT, Gattaz WF, Zarate CA, Machado-Vieira R. Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 468-75. PMID 23072837 DOI: 10.1038/npp.2012.203  0.48
2013 Machado-Vieira R, Luckenbaugh DA, Soeiro-de-Souza MG, Marca G, Henter ID, Busnello JV, Gattaz WF, Zarate CA. Early improvement with lithium in classic mania and its association with later response. Journal of Affective Disorders. 144: 160-4. PMID 22906798 DOI: 10.1016/j.jad.2012.05.039  0.48
2013 Duncan WC, Selter J, Brutsche N, Sarasso S, Zarate CA. Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder. Journal of Affective Disorders. 145: 115-9. PMID 22871531 DOI: 10.1016/j.jad.2012.05.042  0.48
2013 Nugent AC, Luckenbaugh DA, Wood SE, Bogers W, Zarate CA, Drevets WC. Automated subcortical segmentation using FIRST: Test-retest reliability, interscanner reliability, and comparison to manual segmentation Human Brain Mapping. 34: 2313-2329. PMID 22815187 DOI: 10.1002/hbm.22068  0.48
2013 Duncan WC, Sarasso S, Ferrarelli F, Selter J, Riedner BA, Hejazi NS, Yuan P, Brutsche N, Manji HK, Tononi G, Zarate CA. Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 301-11. PMID 22676966 DOI: 10.1017/S1461145712000545  0.48
2013 Nugent AC, Davis RM, Zarate CA, Drevets WC. Reduced thalamic volumes in major depressive disorder Psychiatry Research - Neuroimaging. 213: 179-185. DOI: 10.1016/j.pscychresns.2013.05.004  0.48
2012 de Sousa RT, Busnello JV, Forlenza OV, Zanetti MV, Soeiro-de-Souza MG, van de Bilt MT, Moreno RA, Zarate CA, Gattaz WF, Machado-Vieira R. Early improvement of psychotic symptoms with lithium monotherapy as a predictor of later response in mania. Journal of Psychiatric Research. 46: 1564-8. PMID 23000368 DOI: 10.1016/j.jpsychires.2012.08.011  0.48
2012 Kaddurah-Daouk R, Yuan P, Boyle SH, Matson W, Wang Z, Zeng ZB, Zhu H, Dougherty GG, Yao JK, Chen G, Guitart X, Carlson PJ, Neumeister A, Zarate C, Krishnan RR, et al. Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile. Scientific Reports. 2: 667. PMID 22993692 DOI: 10.1038/srep00667  0.48
2012 Luckenbaugh DA, Ibrahim L, Brutsche N, Franco-Chaves J, Mathews D, Marquardt CA, Cassarly C, Zarate CA. Family history of alcohol dependence and antidepressant response to an N-methyl-D-aspartate antagonist in bipolar depression. Bipolar Disorders. 14: 880-7. PMID 22978511 DOI: 10.1111/bdi.12003  0.48
2012 Zanotti-Fregonara P, Hines CS, Zoghbi SS, Liow JS, Zhang Y, Pike VW, Drevets WC, Mallinger AG, Zarate CA, Fujita M, Innis RB. Population-based input function and image-derived input function for [¹¹C](R)-rolipram PET imaging: methodology, validation and application to the study of major depressive disorder. Neuroimage. 63: 1532-41. PMID 22906792 DOI: 10.1016/j.neuroimage.2012.08.007  0.48
2012 Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C. Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients. Biological Psychiatry. 72: e27-8. PMID 22771240 DOI: 10.1016/j.biopsych.2012.05.031  0.48
2012 Mathews DC, Henter ID, Zarate CA. Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date. Drugs. 72: 1313-33. PMID 22731961 DOI: 10.2165/11633130-000000000-00000  0.48
2012 Ibrahim L, Diaz Granados N, Jolkovsky L, Brutsche N, Luckenbaugh DA, Herring WJ, Potter WZ, Zarate CA. A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder. Journal of Clinical Psychopharmacology. 32: 551-7. PMID 22722512 DOI: 10.1097/JCP.0b013e31825d70d6  0.48
2012 Aan Het Rot M, Zarate CA, Charney DS, Mathew SJ. Ketamine for depression: where do we go from here? Biological Psychiatry. 72: 537-47. PMID 22705040 DOI: 10.1016/j.biopsych.2012.05.003  0.48
2012 Fujita M, Hines CS, Zoghbi SS, Mallinger AG, Dickstein LP, Liow JS, Zhang Y, Pike VW, Drevets WC, Innis RB, Zarate CA. Downregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder. Biological Psychiatry. 72: 548-54. PMID 22677471 DOI: 10.1016/j.biopsych.2012.04.030  0.48
2012 Soeiro-de-Souza MG, Dias VV, Figueira ML, Forlenza OV, Gattaz WF, Zarate CA, Machado-Vieira R. Translating neurotrophic and cellular plasticity: from pathophysiology to improved therapeutics for bipolar disorder. Acta Psychiatrica Scandinavica. 126: 332-41. PMID 22676371 DOI: 10.1111/j.1600-0447.2012.01889.x  0.48
2012 Weathers JD, Stringaris A, Deveney CM, Brotman MA, Zarate CA, Connolly ME, Fromm SJ, LeBourdais SB, Pine DS, Leibenluft E. A developmental study of the neural circuitry mediating motor inhibition in bipolar disorder. The American Journal of Psychiatry. 169: 633-41. PMID 22581312 DOI: 10.1176/appi.ajp.2012.11081244  0.48
2012 Kim P, Thomas LA, Rosen BH, Moscicki AM, Brotman MA, Zarate CA, Blair RJ, Pine DS, Leibenluft E. Differing amygdala responses to facial expressions in children and adults with bipolar disorder. The American Journal of Psychiatry. 169: 642-9. PMID 22535257 DOI: 10.1176/appi.ajp.2012.11081245  0.48
2012 Cornwell BR, Salvadore G, Furey M, Marquardt CA, Brutsche NE, Grillon C, Zarate CA. Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression. Biological Psychiatry. 72: 555-61. PMID 22521148 DOI: 10.1016/j.biopsych.2012.03.029  0.48
2012 Zarate CA, Brutsche N, Laje G, Luckenbaugh DA, Venkata SL, Ramamoorthy A, Moaddel R, Wainer IW. Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biological Psychiatry. 72: 331-8. PMID 22516044 DOI: 10.1016/j.biopsych.2012.03.004  0.48
2012 Furey ML, Nugent AC, Speer AM, Luckenbaugh DA, Hoffman EM, Frankel E, Drevets WC, Zarate CA. Baseline mood-state measures as predictors of antidepressant response to scopolamine. Psychiatry Research. 196: 62-7. PMID 22349648 DOI: 10.1016/j.psychres.2012.01.003  0.48
2012 Ibrahim L, Diazgranados N, Franco-Chaves J, Brutsche N, Henter ID, Kronstein P, Moaddel R, Wainer I, Luckenbaugh DA, Manji HK, Zarate CA. Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1526-33. PMID 22298121 DOI: 10.1038/npp.2011.338  0.48
2012 Zarate CA, Brutsche NE, Ibrahim L, Franco-Chaves J, Diazgranados N, Cravchik A, Selter J, Marquardt CA, Liberty V, Luckenbaugh DA. Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial. Biological Psychiatry. 71: 939-46. PMID 22297150 DOI: 10.1016/j.biopsych.2011.12.010  0.48
2012 Zhao X, Venkata SL, Moaddel R, Luckenbaugh DA, Brutsche NE, Ibrahim L, Zarate CA, Mager DE, Wainer IW. Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression. British Journal of Clinical Pharmacology. 74: 304-14. PMID 22295895 DOI: 10.1111/j.1365-2125.2012.04198.x  0.48
2012 Khairova R, Pawar R, Salvadore G, Juruena MF, de Sousa RT, Soeiro-de-Souza MG, Salvador M, Zarate CA, Gattaz WF, Machado-Vieira R. Effects of lithium on oxidative stress parameters in healthy subjects. Molecular Medicine Reports. 5: 680-2. PMID 22200861 DOI: 10.3892/mmr.2011.732  0.48
2012 Salvadore G, van der Veen JW, Zhang Y, Marenco S, Machado-Vieira R, Baumann J, Ibrahim LA, Luckenbaugh DA, Shen J, Drevets WC, Zarate CA. An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1063-72. PMID 22040773 DOI: 10.1017/S1461145711001593  0.48
2012 Machado-Vieira R, Ibrahim L, Henter ID, Zarate CA. Novel glutamatergic agents for major depressive disorder and bipolar disorder. Pharmacology, Biochemistry, and Behavior. 100: 678-87. PMID 21971560 DOI: 10.1016/j.pbb.2011.09.010  0.48
2012 Malkesman O, Austin DR, Tragon T, Wang G, Rompala G, Hamidi AB, Cui Z, Young WS, Nakazawa K, Zarate CA, Manji HK, Chen G. Acute D-serine treatment produces antidepressant-like effects in rodents. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1135-48. PMID 21906419 DOI: 10.1017/S1461145711001386  0.48
2012 Mathews DC, Henter ID, Zarate CA. New drug developments for bipolar mania Psychiatric Times. 29.  0.48
2011 Kupfer DJ, Angst J, Berk M, Dickerson F, Frangou S, Frank E, Goldstein BI, Harvey A, Laghrissi-Thode F, Leboyer M, Ostacher MJ, Sibille E, Strakowski SM, Suppes T, Tohen M, ... ... Zarate CA, et al. Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder. Annals of the New York Academy of Sciences. 1242: 1-25. PMID 22191553 DOI: 10.1111/j.1749-6632.2011.06336.x  0.48
2011 Ibrahim L, Duncan W, Luckenbaugh DA, Yuan P, Machado-Vieira R, Zarate CA. Rapid antidepressant changes with sleep deprivation in major depressive disorder are associated with changes in vascular endothelial growth factor (VEGF): a pilot study. Brain Research Bulletin. 86: 129-33. PMID 21704134 DOI: 10.1016/j.brainresbull.2011.06.003  0.48
2011 Ibrahim L, Diazgranados N, Luckenbaugh DA, Machado-Vieira R, Baumann J, Mallinger AG, Zarate CA. Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1155-9. PMID 21466832 DOI: 10.1016/j.pnpbp.2011.03.019  0.48
2011 Machado-Vieira R, Zarate CA. Proof of concept trials in bipolar disorder and major depressive disorder: A translational perspective in the search for improved treatments Depression and Anxiety. 28: 267-281. PMID 21456037 DOI: 10.1002/da.20800  0.48
2011 Mathew SJ, Vythilingam M, Murrough JW, Zarate CA, Feder A, Luckenbaugh DA, Kinkead B, Parides MK, Trist DG, Bani MS, Bettica PU, Ratti EM, Charney DS. A selective neurokinin-1 receptor antagonist in chronic PTSD: a randomized, double-blind, placebo-controlled, proof-of-concept trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 221-9. PMID 21194898 DOI: 10.1016/j.euroneuro.2010.11.012  0.48
2011 Machado-Vieira R, Pivovarova NB, Stanika RI, Yuan P, Wang Y, Zhou R, Zarate CA, Drevets WC, Brantner CA, Baum A, Laje G, McMahon FJ, Chen G, Du J, Manji HK, et al. The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder. Biological Psychiatry. 69: 344-52. PMID 21167476 DOI: 10.1016/j.biopsych.2010.10.019  0.48
2011 Savitz JB, Nugent AC, Bogers W, Roiser JP, Bain EE, Neumeister A, Zarate CA, Manji HK, Cannon DM, Marrett S, Henn F, Charney DS, Drevets WC. Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study. Biological Psychiatry. 69: 336-43. PMID 21094939 DOI: 10.1016/j.biopsych.2010.09.027  0.48
2011 Salvadore G, Nugent AC, Lemaitre H, Luckenbaugh DA, Tinsley R, Cannon DM, Neumeister A, Zarate CA, Drevets WC. Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder. Neuroimage. 54: 2643-51. PMID 21073959 DOI: 10.1016/j.neuroimage.2010.11.011  0.48
2011 Mah L, Zarate CA, Nugent AC, Singh JB, Manji HK, Drevets WC. Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression International Journal of Neuropsychopharmacology. 14: 545-551. PMID 21029512 DOI: 10.1017/S1461145710001203  0.48
2011 Machado-Vieira R, Ibrahim L, Zarate CA. Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene-Environment Interactions Cns Neuroscience and Therapeutics. 17: 699-704. PMID 20961400 DOI: 10.1111/j.1755-5949.2010.00203.x  0.48
2011 Salvatore P, Baldessarini RJ, Tohen M, Khalsa HMK, Sanchez-Toledo JP, Zarate CA, Vieta E, Maggini C. McLean-Harvard international first-episode project: Two-year stability of ICD-10 diagnoses in 500 first-episode psychotic disorder patients Journal of Clinical Psychiatry. 72: 183-193. PMID 20673546 DOI: 10.4088/JCP.09m05311yel  0.48
2011 Manji HK, Henter ID, Zarate CA. Bipolar Disorder: A Neurobiological Synthesis Current Topics in Behavioral Neurosciences. 5: 331-340. DOI: 10.1007/7854_2010_98  0.48
2011 Machado-Vieira R, Manji HK, Zarate CA. Potential novel therapeutics for bipolar disorders Current Topics in Behavioral Neurosciences. 5: 303-329. DOI: 10.1007/7854_2010_51  0.48
2011 Machado-Vieira R, Henter I, Baumann J, Latov D, Wheeler-Castillo C, Zarate CA. Novel Therapeutic Approaches for Treating Bipolar Disorder Bipolar Psychopharmacotherapy: Caring For the Patient: Second Edition. 423-445. DOI: 10.1002/9780470975114.ch21  0.48
2011 Manji HK, Zarate CA. Behavioral neurobiology of bipolar disorder and its treatment Current Topics in Behavioral Neurosciences. 5.  0.48
2011 Zarate CA, Henter ID, Manji HK. Preface Current Topics in Behavioral Neurosciences. 5: v-ix.  0.48
2010 Machado-Vieira R, Baumann J, Wheeler-Castillo C, Latov D, Henter ID, Salvadore G, Zarate CA. The Timing of Antidepressant Effects: A Comparison of Diverse Pharmacological and Somatic Treatments. Pharmaceuticals (Basel, Switzerland). 3: 19-41. PMID 27713241 DOI: 10.3390/ph3010019  0.48
2010 Salvadore G, Zarate CA. Magnetic resonance spectroscopy studies of the glutamatergic system in mood disorders: A pathway to diagnosis, novel therapeutics, and personalized medicine? Biological Psychiatry. 68: 780-782. PMID 20946973 DOI: 10.1016/j.biopsych.2010.09.011  0.48
2010 Diazgranados N, Ibrahim L, Brutsche NE, Newberg A, Kronstein P, Khalife S, Kammerer WA, Quezado Z, Luckenbaugh DA, Salvadore G, Machado-Vieira R, Manji HK, Zarate CA. A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression Archives of General Psychiatry. 67: 793-802. PMID 20679587 DOI: 10.1001/archgenpsychiatry.2010.90  0.48
2010 DiazGranados N, Ibrahim LA, Brutsche NE, Ameli R, Henter ID, Luckenbaugh DA, Machado-Vieira R, Zarate CA. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder Journal of Clinical Psychiatry. 71: 1605-1611. PMID 20673547 DOI: 10.4088/JCP.09m05327blu  0.48
2010 Schaefer KL, Baumann J, Rich BA, Luckenbaugh DA, Zarate CA. Perception of facial emotion in adults with bipolar or unipolar depression and controls. Journal of Psychiatric Research. 44: 1229-35. PMID 20510425 DOI: 10.1016/j.jpsychires.2010.04.024  0.48
2010 Salvadore G, Quiroz JA, Machado-Vieira R, Henter ID, Manji HK, Zarate CA. The neurobiology of the switch process in bipolar disorder: A review Journal of Clinical Psychiatry. 71: 1488-1501. PMID 20492846 DOI: 10.4088/JCP.09r05259gre  0.48
2010 Quiroz JA, MacHado-Vieira R, Zarate CA, Manji HK. Novel insights into lithium's mechanism of action: Neurotrophic and neuroprotective effects Neuropsychobiology. 62: 50-60. PMID 20453535 DOI: 10.1159/000314310  0.48
2010 Cornwell BR, Salvadore G, Colon-Rosario V, Latov DR, Holroyd T, Carver FW, Coppola R, Manji HK, Zarate CA, Grillon C. Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography. The American Journal of Psychiatry. 167: 836-44. PMID 20439387 DOI: 10.1176/appi.ajp.2009.09050614  0.48
2010 Machado-Vieira R, Salvadore G, DiazGranados N, Ibrahim L, Latov D, Wheeler-Castillo C, Baumann J, Henter ID, Zarate CA. New therapeutic targets for mood disorders. Thescientificworldjournal. 10: 713-26. PMID 20419280 DOI: 10.1100/tsw.2010.65  0.48
2010 Salvadore G, Cornwell BR, Sambataro F, Latov D, Colon-Rosario V, Carver F, Holroyd T, DiazGranados N, Machado-Vieira R, Grillon C, Drevets WC, Zarate CA. Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1415-22. PMID 20393460 DOI: 10.1038/npp.2010.24  0.48
2010 Salvadore G, Viale CI, Luckenbaugh DA, Zanatto VC, Portela LV, Souza DO, Zarate CA, Machado-Vieira R. Increased uric acid levels in drug-naïve subjects with bipolar disorder during a first manic episode Progress in Neuro-Psychopharmacology and Biological Psychiatry. 34: 819-821. PMID 20206224 DOI: 10.1016/j.pnpbp.2010.02.027  0.48
2010 Tamayo JM, Zarate CA, Vieta E, Vazquez G, Tohen M. Level of response and safety of pharmacological monotherapy in the treatment of acute bipolar i disorder phases: A systematic review and meta-analysis International Journal of Neuropsychopharmacology. 13: 813-832. PMID 20128953 DOI: 10.1017/S1461145709991246  0.48
2010 Salvadore G, Henter ID, Zarate CA. Dr Salvadore and colleagues reply Journal of Clinical Psychiatry. 71: 1699-1700. DOI: 10.4088/JCP.10lr06389ayel  0.48
2010 Machado-Vieira R, Baumann J, Wheeler-Castillo C, Latov D, Henter ID, Salvadore G, Zarate CA. The timing of antidepressant effects: A comparison of diverse pharmacological and somatic treatments Pharmaceuticals. 3: 19-41. DOI: 10.3390/ph3010019  0.48
2010 Manji HK, Zarate CA, Chen G, Du J. Mood Stabilizers Encyclopedia of Neuroscience. 967-974. DOI: 10.1016/B978-008045046-9.00388-0  0.48
2010 Machado-Vieira R, Manji HK, Zarate CA. Novel Therapeutic Strategies for Bipolar Disorder Bipolar Disorder: Clinical and Neurobiological Foundations. 395-411. DOI: 10.1002/9780470661277.ch30  0.48
2009 Machado-Vieira R, Yuan P, Brutsche N, DiazGranados N, Luckenbaugh D, Manji HK, Zarate CA. Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist Journal of Clinical Psychiatry. 70: 1662-1666. PMID 19744406 DOI: 10.4088/JCP.08m04659  0.48
2009 Tamayo JM, Sutton VK, Mattei MA, Diaz B, Jamal HH, Vieta E, Zarate CA, Fumero I, Tohen M. Effectiveness and safety of the combination of fluoxetine and olanzapine in outpatients with bipolar depression: an open-label, randomized, flexible-dose study in Puerto Rico. Journal of Clinical Psychopharmacology. 29: 358-61. PMID 19593175 DOI: 10.1097/JCP.0b013e3181ad223f  0.48
2009 Salvadore G, Nugent AC, Chen G, Akula N, Yuan P, Cannon DM, Zarate CA, McMahon FJ, Manji HK, Drevets WC. Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans. Biological Psychiatry. 66: 804-7. PMID 19589501 DOI: 10.1016/j.biopsych.2009.05.025  0.48
2009 Zarate CA, Manji HK. Protein kinase C inhibitors: Rationale for use and potential in the treatment of bipolar disorder Cns Drugs. 23: 569-582. PMID 19552485 DOI: 10.2165/00023210-200923070-00003  0.48
2009 Machado-Vieira R, Manji HK, Zarate CA. The role of lithium in the treatment of bipolar disorder: Convergent evidence for neurotrophic effects as a unifying hypothesis Bipolar Disorders. 11: 92-109. PMID 19538689 DOI: 10.1111/j.1399-5618.2009.00714.x  0.48
2009 MacHado-Vieira R, Manji HK, Zarate CA. The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders Neuroscientist. 15: 525-539. PMID 19471044 DOI: 10.1177/1073858409336093  0.48
2009 Machado-Vieira R, Salvadore G, Ibrahim LA, Diaz-Granados N, Zarate CA. Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders Current Pharmaceutical Design. 15: 1595-1611. PMID 19442176 DOI: 10.2174/138161209788168010  0.48
2009 Machado-Vieira R, Salvadore G, DiazGranados N, Zarate CA. Ketamine and the next generation of antidepressants with a rapid onset of action Pharmacology and Therapeutics. 123: 143-150. PMID 19397926 DOI: 10.1016/j.pharmthera.2009.02.010  0.48
2009 Roiser JP, Cannon DM, Gandhi SK, Taylor Tavares J, Erickson K, Wood S, Klaver JM, Clark L, Zarate CA, Sahakian BJ, Drevets WC. Hot and cold cognition in unmedicated depressed subjects with bipolar disorder. Bipolar Disorders. 11: 178-89. PMID 19267700 DOI: 10.1111/j.1399-5618.2009.00669.x  0.48
2009 Salvatore P, Baldessarini RJ, Tohen M, Khalsa HMK, Perez Sanchez-Toledo J, Zarate CA, Vieta E, Maggini C. McLean-Harvard International First-Episode Project: Two-year stability of DSM-IV diagnoses in 500 first-episode psychotic disorder patients Journal of Clinical Psychiatry. 70: 458-466. PMID 19200422 DOI: 10.4088/JCP.08m04227  0.48
2009 Salvadore G, Cornwell BR, Colon-Rosario V, Coppola R, Grillon C, Zarate CA, Manji HK. Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biological Psychiatry. 65: 289-95. PMID 18822408 DOI: 10.1016/j.biopsych.2008.08.014  0.48
2009 Maeng S, Zarate CA, Du J, Schloesser RJ, McCammon J, Chen G, Manji HK. Cellular mechanisms forming the basis of the antidepressant effects of ketamine: Role of alpha-amino-3-hydroxymethylisoxazol-4-propionic acid receptors | Mecanismos celulares que son la base de los efectos antidepresivos de la ketamina: Papel de los receptores del ácido alfa-amino-3- hidroximetilisoxazol-4-propiónico Psiquiatria Biologica. 16: 141-147.  0.48
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