David K. Welsh, MD/PhD - Publications

Psychiatry University of California, San Diego, La Jolla, CA 
Circadian Rhythms

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Meadows JD, Breuer JA, Lavalle SN, Hirschenberger MR, Patel MM, Nguyen D, Kim A, Cassin J, Gorman MR, Welsh DK, Mellon PL, Hoffmann HM. Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved metabolic function, and dwarfism in male mice. Molecular Metabolism. 101431. PMID 34974160 DOI: 10.1016/j.molmet.2021.101431  0.59
2021 Hoffmann HM, Meadows JD, Breuer JA, Yaw AM, Nguyen D, Tonsfeldt KJ, Chin AY, Devries BM, Trang C, Oosterhouse HJ, Lee JS, Doser JW, Gorman MR, Welsh DK, Mellon PL. The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. Journal of Neuroscience Research. PMID 34212416 DOI: 10.1002/jnr.24864  0.624
2021 Evans JA, Welsh DK, Davidson AJ. Collection of Mouse Brain Slices for Bioluminescence Imaging of Circadian Clock Networks. Methods in Molecular Biology (Clifton, N.J.). 2130: 287-294. PMID 33284452 DOI: 10.1007/978-1-0716-0381-9_21  0.645
2020 Porcu A, Vaughan M, Nilsson A, Arimoto N, Lamia K, Welsh DK. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 32487727 DOI: 10.1073/Pnas.2000258117  0.461
2019 Haque SN, Booreddy SR, Welsh DK. Effects of BMAL1 Manipulation on the Brain's Master Circadian Clock and Behavior. The Yale Journal of Biology and Medicine. 92: 251-258. PMID 31249486  0.424
2018 McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, et al. Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30487653 DOI: 10.1038/S41386-018-0273-8  0.434
2018 Hühne A, Welsh DK, Landgraf D. Prospects for Circadian Treatment of Mood Disorders. Annals of Medicine. 1-35. PMID 30265156 DOI: 10.1080/07853890.2018.1530449  0.396
2018 Noguchi T, Harrison EM, Sun J, May D, Ng A, Welsh DK, Gorman MR. Circadian rhythm bifurcation induces flexible phase resetting by reducing circadian amplitude. The European Journal of Neuroscience. PMID 30044021 DOI: 10.1111/Ejn.14086  0.8
2018 Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, et al. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell. PMID 29861175 DOI: 10.1016/J.Cell.2018.05.009  0.486
2018 Porcu A, Riddle M, Dulcis D, Welsh DK. Photoperiod-Induced Neuroplasticity in the Circadian System. Neural Plasticity. 2018: 5147585. PMID 29681926 DOI: 10.1155/2018/5147585  0.43
2018 Mei L, Fan Y, Lv X, Welsh DK, Zhan C, Zhang EE. Long-term in vivo recording of circadian rhythms in brains of freely moving mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610316 DOI: 10.1073/Pnas.1717735115  0.672
2017 Noguchi T, Leise TL, Kingsbury NJ, Diemer T, Wang LL, Henson MA, Welsh DK. Calcium Circadian Rhythmicity in the Suprachiasmatic Nucleus: Cell Autonomy and Network Modulation. Eneuro. 4. PMID 28828400 DOI: 10.1523/ENEURO.0160-17.2017  0.317
2017 Diemer T, Landgraf D, Noguchi T, Pan H, Moreno JL, Welsh DK. Cellular Circadian Oscillators in the Suprachiasmatic Nucleus Remain Coupled in the Absence of Connexin-36. Neuroscience. PMID 28576728 DOI: 10.1016/J.Neuroscience.2017.05.037  0.549
2017 Kiessling S, Beaulieu-Laroche L, Blum ID, Landgraf D, Welsh DK, Storch KF, Labrecque N, Cermakian N. Enhancing circadian clock function in cancer cells inhibits tumor growth. Bmc Biology. 15: 13. PMID 28196531 DOI: 10.1186/S12915-017-0349-7  0.416
2017 Landgraf D, Barandas R, Long J, Proulx C, McCarthy M, Malinow R, Welsh D. The role of disturbed circadian clocks in the development of depression-like behavior and metabolic comorbidity in mice European Psychiatry. 41: S531-S531. DOI: 10.1016/J.Eurpsy.2017.01.721  0.52
2016 Beesley S, Noguchi T, Welsh DK. Cardiomyocyte Circadian Oscillations Are Cell-Autonomous, Amplified by β-Adrenergic Signaling, and Synchronized in Cardiac Ventricle Tissue. Plos One. 11: e0159618. PMID 27459195 DOI: 10.1371/Journal.Pone.0159618  0.459
2016 Roberts L, Leise TL, Welsh DK, Holmes TC. Functional Contributions of Strong and Weak Cellular Oscillators to Synchrony and Light-shifted Phase Dynamics. Journal of Biological Rhythms. PMID 27221103 DOI: 10.1177/0748730416649550  0.521
2016 McCarthy MJ, Wei H, Landgraf D, Le Roux MJ, Welsh DK. Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27216486 DOI: 10.1016/J.Euroneuro.2016.05.003  0.426
2016 Landgraf D, Long JE, Proulx CD, Barandas R, Malinow R, Welsh DK. Genetic Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus Causes Helplessness, Behavioral Despair, and Anxiety-like Behavior in Mice. Biological Psychiatry. PMID 27113500 DOI: 10.1016/J.Biopsych.2016.03.1050  0.534
2016 Landgraf D, Joiner WJ, McCarthy MJ, Kiessling S, Barandas R, Young JW, Cermakian N, Welsh DK. The Mood Stabilizer Valproic Acid Opposes the Effects of Dopamine on Circadian Rhythms. Neuropharmacology. PMID 27033596 DOI: 10.1016/J.Neuropharm.2016.03.047  0.529
2016 Noguchi T, Lo K, Diemer T, Welsh DK. Lithium effects on circadian rhythms in fibroblasts and suprachiasmatic nucleus slices from Cry knockout mice. Neuroscience Letters. PMID 26930624 DOI: 10.1016/J.Neulet.2016.02.030  0.513
2016 Landgraf D, Wang LL, Diemer T, Welsh DK. NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators. Plos Genetics. 12: e1005882. PMID 26895328 DOI: 10.1371/Journal.Pgen.1005882  0.58
2015 Barandas R, Landgraf D, McCarthy MJ, Welsh DK. Circadian Clocks as Modulators of Metabolic Comorbidity in Psychiatric Disorders. Current Psychiatry Reports. 17: 98. PMID 26483181 DOI: 10.1007/S11920-015-0637-2  0.395
2015 McCarthy MJ, Le Roux MJ, Wei H, Beesley S, Kelsoe JR, Welsh DK. Calcium channel genes associated with bipolar disorder modulate lithium's amplification of circadian rhythms. Neuropharmacology. 101: 439-448. PMID 26476274 DOI: 10.1016/J.Neuropharm.2015.10.017  0.423
2015 Landgraf D, Long JE, Welsh DK. Depression-Like Behavior in Mice is Associated with Disrupted Circadian Rhythms in Nucleus Accumbens and Periaqueductal Gray. The European Journal of Neuroscience. PMID 26414405 DOI: 10.1111/Ejn.13085  0.503
2015 Kripke DF, Elliott JA, Welsh DK, Youngstedt SD. Photoperiodic and circadian bifurcation theories of depression and mania. F1000research. 4: 107. PMID 26180634 DOI: 10.12688/F1000Research.6444.1  0.402
2015 Roberts L, Leise TL, Noguchi T, Galschiodt AM, Houl JH, Welsh DK, Holmes TC. Light evokes rapid circadian network oscillator desynchrony followed by gradual phase retuning of synchrony. Current Biology : Cb. 25: 858-67. PMID 25754644 DOI: 10.1016/J.Cub.2015.01.056  0.506
2014 Landgraf D, McCarthy MJ, Welsh DK. Circadian clock and stress interactions in the molecular biology of psychiatric disorders. Current Psychiatry Reports. 16: 483. PMID 25135782 DOI: 10.1007/S11920-014-0483-7  0.41
2014 Ramanathan C, Xu H, Khan SK, Shen Y, Gitis PJ, Welsh DK, Hogenesch JB, Liu AC. Cell type-specific functions of period genes revealed by novel adipocyte and hepatocyte circadian clock models. Plos Genetics. 10: e1004244. PMID 24699442 DOI: 10.1371/Journal.Pgen.1004244  0.77
2014 Landgraf D, McCarthy MJ, Welsh DK. The role of the circadian clock in animal models of mood disorders. Behavioral Neuroscience. 128: 344-59. PMID 24660657 DOI: 10.1037/A0036029  0.476
2013 McCarthy MJ, Wei H, Marnoy Z, Darvish RM, McPhie DL, Cohen BM, Welsh DK. Genetic and clinical factors predict lithium's effects on PER2 gene expression rhythms in cells from bipolar disorder patients. Translational Psychiatry. 3: e318. PMID 24150227 DOI: 10.1038/Tp.2013.90  0.446
2013 Noguchi T, Wang LL, Welsh DK. Fibroblast PER2 circadian rhythmicity depends on cell density. Journal of Biological Rhythms. 28: 183-92. PMID 23735497 DOI: 10.1177/0748730413487494  0.39
2013 McCarthy MJ, Fernandes M, Kranzler HR, Covault JM, Welsh DK. Circadian clock period inversely correlates with illness severity in cells from patients with alcohol use disorders. Alcoholism, Clinical and Experimental Research. 37: 1304-10. PMID 23550834 DOI: 10.1111/Acer.12106  0.407
2012 Evans JA, Pan H, Liu AC, Welsh DK. Cry1-/- circadian rhythmicity depends on SCN intercellular coupling. Journal of Biological Rhythms. 27: 443-52. PMID 23223370 DOI: 10.1177/0748730412461246  0.75
2012 McCarthy MJ, Welsh DK. Cellular circadian clocks in mood disorders. Journal of Biological Rhythms. 27: 339-52. PMID 23010657 DOI: 10.1177/0748730412456367  0.506
2012 Cohen AL, Leise TL, Welsh DK. Bayesian statistical analysis of circadian oscillations in fibroblasts. Journal of Theoretical Biology. 314: 182-91. PMID 22982138 DOI: 10.1016/J.Jtbi.2012.08.038  0.328
2012 Welsh DK, Noguchi T. Cellular bioluminescence imaging. Cold Spring Harbor Protocols. 2012. PMID 22854570 DOI: 10.1101/Pdb.Top070607  0.316
2012 Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T, Welsh DK, Brenner DA, Doyle FJ, Schultz PG, Kay SA. Identification of small molecule activators of cryptochrome. Science (New York, N.Y.). 337: 1094-7. PMID 22798407 DOI: 10.1126/Science.1223710  0.715
2012 Noguchi T, Wang CW, Pan H, Welsh DK. Fibroblast circadian rhythms of PER2 expression depend on membrane potential and intracellular calcium. Chronobiology International. 29: 653-64. PMID 22734566 DOI: 10.3109/07420528.2012.679330  0.406
2012 Leise TL, Wang CW, Gitis PJ, Welsh DK. Persistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2::LUC bioluminescence. Plos One. 7: e33334. PMID 22479387 DOI: 10.1371/Journal.Pone.0033334  0.471
2012 McCarthy MJ, Nievergelt CM, Kelsoe JR, Welsh DK. A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response. Plos One. 7: e32091. PMID 22384149 DOI: 10.1371/Journal.Pone.0032091  0.413
2011 McCarthy MJ, Nievergelt CM, Shekhtman T, Kripke DF, Welsh DK, Kelsoe JR. Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder. Genes, Brain, and Behavior. 10: 852-61. PMID 21781277 DOI: 10.1111/J.1601-183X.2011.00725.X  0.376
2011 Meeker K, Harang R, Webb AB, Welsh DK, Doyle FJ, Bonnet G, Herzog ED, Petzold LR. Wavelet measurement suggests cause of period instability in mammalian circadian neurons. Journal of Biological Rhythms. 26: 353-62. PMID 21775294 DOI: 10.1177/0748730411409863  0.496
2011 Foley NC, Tong TY, Foley D, Lesauter J, Welsh DK, Silver R. Characterization of orderly spatiotemporal patterns of clock gene activation in mammalian suprachiasmatic nucleus. The European Journal of Neuroscience. 33: 1851-65. PMID 21488990 DOI: 10.1111/J.1460-9568.2011.07682.X  0.503
2010 Ko CH, Yamada YR, Welsh DK, Buhr ED, Liu AC, Zhang EE, Ralph MR, Kay SA, Forger DB, Takahashi JS. Emergence of noise-induced oscillations in the central circadian pacemaker. Plos Biology. 8: e1000513. PMID 20967239 DOI: 10.1371/Journal.Pbio.1000513  0.785
2010 Welsh DK, Takahashi JS, Kay SA. Suprachiasmatic nucleus: cell autonomy and network properties. Annual Review of Physiology. 72: 551-77. PMID 20148688 DOI: 10.1146/Annurev-Physiol-021909-135919  0.662
2010 Ko CH, Yamada YR, Welsh DK, Buhr ED, Liu AC, Zhang EE, Ralph MR, Kay SA, Forger DB, Takahashi JS. Correction: Emergence of Noise-Induced Oscillations in the Central Circadian Pacemaker Plos Biology. 8. DOI: 10.1371/Annotation/45E0Bb8B-69Bd-4Ba0-Bb9E-6641Bce10Fc6  0.688
2009 Westermark PO, Welsh DK, Okamura H, Herzel H. Quantification of circadian rhythms in single cells. Plos Computational Biology. 5: e1000580. PMID 19956762 DOI: 10.1371/Journal.Pcbi.1000580  0.482
2009 Wang LM, Dragich JM, Kudo T, Odom IH, Welsh DK, O'Dell TJ, Colwell CS. Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. Asn Neuro. 1. PMID 19570032 DOI: 10.1042/An20090020  0.489
2009 Mirsky HP, Liu AC, Welsh DK, Kay SA, Doyle FJ. A model of the cell-autonomous mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 106: 11107-12. PMID 19549830 DOI: 10.1073/Pnas.0904837106  0.749
2009 Welsh DK. Limits of single-cell autonomy in the suprachiasmatic nucleus Sleep and Biological Rhythms. 7: 252-259. DOI: 10.1111/J.1479-8425.2009.00425.X  0.551
2008 Liu AC, Tran HG, Zhang EE, Priest AA, Welsh DK, Kay SA. Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. Plos Genetics. 4: e1000023. PMID 18454201 DOI: 10.1371/Journal.Pgen.1000023  0.786
2007 Yan L, Karatsoreos I, Lesauter J, Welsh DK, Kay S, Foley D, Silver R. Exploring spatiotemporal organization of SCN circuits. Cold Spring Harbor Symposia On Quantitative Biology. 72: 527-41. PMID 18419312 DOI: 10.1101/Sqb.2007.72.037  0.635
2007 Pulivarthy SR, Tanaka N, Welsh DK, De Haro L, Verma IM, Panda S. Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 104: 20356-61. PMID 18077393 DOI: 10.1073/Pnas.0708877104  0.608
2007 Forger D, Gonze D, Virshup D, Welsh DK. Beyond intuitive modeling: combining biophysical models with innovative experiments to move the circadian clock field forward. Journal of Biological Rhythms. 22: 200-10. PMID 17517910 DOI: 10.1177/0748730407301823  0.402
2007 Liu AC, Welsh DK, Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED, Singer O, Meeker K, Verma IM, Doyle FJ, Takahashi JS, Kay SA. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell. 129: 605-16. PMID 17482552 DOI: 10.1016/J.Cell.2007.02.047  0.791
2007 Welsh DK. VIP activates and couples clock cells. Focus on "Disrupted neuronal activity rhythms in the suprachiasmatic nucleus of vasoactive intestinal polypeptide-deficient mice". Journal of Neurophysiology. 97: 1885-6. PMID 17251373 DOI: 10.1152/Jn.00063.2007  0.438
2007 Welsh DK. Gate cells see the light. Journal of Biological Rhythms. 22: 26-8. PMID 17229922 DOI: 10.1177/0748730406297067  0.365
2006 Sato TK, Yamada RG, Ukai H, Baggs JE, Miraglia LJ, Kobayashi TJ, Welsh DK, Kay SA, Ueda HR, Hogenesch JB. Feedback repression is required for mammalian circadian clock function. Nature Genetics. 38: 312-9. PMID 16474406 DOI: 10.1038/Ng1745  0.739
2005 Welsh DK, Imaizumi T, Kay SA. Real-time reporting of circadian-regulated gene expression by luciferase imaging in plants and mammalian cells. Methods in Enzymology. 393: 269-88. PMID 15817294 DOI: 10.1016/S0076-6879(05)93011-5  0.732
2005 Welsh DK, Kay SA. Bioluminescence imaging in living organisms. Current Opinion in Biotechnology. 16: 73-8. PMID 15722018 DOI: 10.1016/J.Copbio.2004.12.006  0.581
2004 Welsh DK, Yoo SH, Liu AC, Takahashi JS, Kay SA. Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Current Biology : Cb. 14: 2289-95. PMID 15620658 DOI: 10.1016/J.Cub.2004.11.057  0.762
2003 Monk TH, Welsh DK. The role of chronobiology in sleep disorders medicine. Sleep Medicine Reviews. 7: 455-73. PMID 15018090 DOI: 10.1016/S1087-0792(03)90001-3  0.34
1996 Welsh DK, Reppert SM. Gap junctions couple astrocytes but not neurons in dissociated cultures of rat suprachiasmatic nucleus. Brain Research. 706: 30-6. PMID 8720489 DOI: 10.1016/0006-8993(95)01172-2  0.632
1995 Welsh DK, Logothetis DE, Meister M, Reppert SM. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron. 14: 697-706. PMID 7718233 DOI: 10.1016/0896-6273(95)90214-7  0.663
1990 Nadakavukaren JJ, Welsh DK, Reppert SM. Aluminum fluoride reveals a phosphoinositide system within the suprachiasmatic region of rat hypothalamus. Brain Research. 507: 181-8. PMID 2159821 DOI: 10.1016/0006-8993(90)90270-L  0.548
1990 Welsh DK, Moore-Ede MC. Lithium lengthens circadian period in a diurnal primate, Saimiri sciureus. Biological Psychiatry. 28: 117-26. PMID 2116188 DOI: 10.1016/0006-3223(90)90629-G  0.41
1988 Welsh D, Richardson GS, Dement WC. Effect of running wheel availability on circadian patterns of sleep and wakefulness in mice. Physiology & Behavior. 43: 771-77. PMID 3237790 DOI: 10.1016/0031-9384(88)90375-7  0.335
1986 Welsh DK, Richardson GS, Dement WC. Effect of age on the circadian pattern of sleep and wakefulness in the mouse. Journal of Gerontology. 41: 579-86. PMID 3745812 DOI: 10.1093/Geronj/41.5.579  0.31
1986 Welsh DK, Engel EM, Richardson GS, Dement WC, Engle EM. Precision of circadian wake and activity onset timing in the mouse. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 158: 827-34. PMID 3735167 DOI: 10.1007/Bf01324824  0.424
1985 Welsh DK, Richardson GS, Dement WC. A circadian rhythm of hippocampal theta activity in the mouse. Physiology & Behavior. 35: 533-8. PMID 4070426 DOI: 10.1016/0031-9384(85)90136-2  0.369
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