Malcolm Whiteway - Publications

Affiliations: 
Genomics University of Alberta, Edmonton, Alberta, Canada 

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rashid S, Correia-Mesquita TO, Godoy P, Omran RP, Whiteway M. SAGA Complex Subunits in Differentially Regulate Filamentation, Invasiveness, and Biofilm Formation. Frontiers in Cellular and Infection Microbiology. 12: 764711. PMID 35350439 DOI: 10.3389/fcimb.2022.764711  0.313
2021 Omran RP, Ramírez-Zavala B, Aji Tebung W, Yao S, Feng J, Law C, Dumeaux V, Morschhäuser J, Whiteway M. The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans. Genetics. PMID 34849863 DOI: 10.1093/genetics/iyab155  0.338
2021 Shrivastava M, Feng J, Coles M, Clark B, Islam A, Dumeaux V, Whiteway M. Modulation of the complex regulatory network for methionine biosynthesis in fungi. Genetics. 217. PMID 33724418 DOI: 10.1093/genetics/iyaa049  0.336
2020 Xu H, Fang T, Omran RP, Whiteway M, Jiang L. RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans. Cell Communication and Signaling : Ccs. 18: 1. PMID 31900175 DOI: 10.1186/s12964-019-0473-9  0.314
2019 Costa ACBP, Omran RP, Correia-Mesquita TO, Dumeaux V, Whiteway M. Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1. Scientific Reports. 9: 9187. PMID 31235750 DOI: 10.1038/s41598-019-45624-y  0.328
2019 Polvi EJ, Veri AO, Liu Z, Hossain S, Hyde S, Kim SH, Tebbji F, Sellam A, Todd RT, Xie JL, Lin ZY, Wong CJ, Shapiro RS, Whiteway M, Robbins N, et al. Functional divergence of a global regulatory complex governing fungal filamentation. Plos Genetics. 15: e1007901. PMID 30615616 DOI: 10.1371/Journal.Pgen.1007901  0.351
2018 Islam A, Tebbji F, Mallick J, Regan H, Dumeaux V, Omran RP, Whiteway M. Mms21: A Putative SUMO E3 Ligase in That Negatively Regulates Invasiveness and Filamentation, and Is Required for Genotoxic and Cellular Stress Response. Genetics. PMID 30530734 DOI: 10.1534/genetics.118.301769  0.307
2017 Tebung WA, Omran RP, Fulton DL, Morschhäuser J, Whiteway M. Put3 Positively Regulates Proline Utilization in Candida albicans. Msphere. 2. PMID 29242833 DOI: 10.1128/mSphere.00354-17  0.341
2017 Tebbji F, Chen Y, Sellam A, Whiteway M. The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans. Msphere. 2. PMID 29152582 DOI: 10.1128/mSphere.00497-17  0.35
2017 Regan H, Scaduto C, Hirakawa MP, Gunsalus K, Correia-Mesquita TO, Sun Y, Chen Y, Kumamoto CA, Bennett R, Whiteway M. Negative Regulation of Filamentous Growth in Candida albicans by Dig1p. Molecular Microbiology. PMID 28657681 DOI: 10.1111/Mmi.13738  0.346
2016 Sun Y, Gadoury C, Hirakawa MP, Bennett RJ, Harcus D, Marcil A, Whiteway M. Deletion of a Yci1 Domain Protein of Candida albicans Allows Homothallic Mating in MTL Heterozygous Cells. Mbio. 7. PMID 27118591 DOI: 10.1128/mBio.00465-16  0.326
2015 Lu H, Yao XW, Whiteway M, Xiong J, Liao ZB, Jiang YY, Cao YY. Loss of RPS41 but not its paralog RPS42 results in altered growth, filamentation and transcriptome changes in Candida albicans. Fungal Genetics and Biology : Fg & B. 80: 31-42. PMID 25937438 DOI: 10.1016/j.fgb.2015.03.012  0.359
2014 Tebbji F, Chen Y, Richard Albert J, Gunsalus KT, Kumamoto CA, Nantel A, Sellam A, Whiteway M. A functional portrait of Med7 and the mediator complex in Candida albicans. Plos Genetics. 10: e1004770. PMID 25375174 DOI: 10.1371/Journal.Pgen.1004770  0.357
2014 Lu H, Sun Y, Jiang YY, Whiteway M. Ste18p is a positive control element in the mating process of Candida albicans. Eukaryotic Cell. 13: 461-9. PMID 24489040 DOI: 10.1128/EC.00320-13  0.357
2013 Harcus D, Dignard D, Lépine G, Askew C, Raymond M, Whiteway M, Wu C. Comparative xylose metabolism among the Ascomycetes C. albicans, S. stipitis and S. cerevisiae. Plos One. 8: e80733. PMID 24236198 DOI: 10.1371/Journal.Pone.0080733  0.427
2013 Epp E, Nazarova E, Regan H, Douglas LM, Konopka JB, Vogel J, Whiteway M. Clathrin- and Arp2/3-independent endocytosis in the fungal pathogen Candida albicans. Mbio. 4: e00476-13. PMID 23982070 DOI: 10.1128/Mbio.00476-13  0.415
2013 Mallick J, Whiteway M. The evolutionary rewiring of the ribosomal protein transcription pathway modifies the interaction of transcription factor heteromer Ifh1-Fhl1 (interacts with forkhead 1-forkhead-like 1) with the DNA-binding specificity element. The Journal of Biological Chemistry. 288: 17508-19. PMID 23625919 DOI: 10.1074/jbc.M112.436683  0.339
2013 Yerko V, Sulea T, Ekiel I, Harcus D, Baardsnes J, Cygler M, Whiteway M, Wu C. Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signaling. Molecular Biology of the Cell. 24: 409-20. PMID 23242997 DOI: 10.1091/Mbc.E12-07-0516  0.324
2013 Pierce JV, Dignard D, Whiteway M, Kumamoto CA. Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryotic Cell. 12: 37-49. PMID 23125349 DOI: 10.1128/Ec.00236-12  0.456
2012 Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, ... ... Whiteway M, et al. Global gene deletion analysis exploring yeast filamentous growth. Science (New York, N.Y.). 337: 1353-6. PMID 22984072 DOI: 10.1126/Science.1224339  0.451
2012 Sellam A, Tebbji F, Whiteway M, Nantel A. A novel role for the transcription factor Cwt1p as a negative regulator of nitrosative stress in Candida albicans. Plos One. 7: e43956. PMID 22952822 DOI: 10.1371/Journal.Pone.0043956  0.451
2012 Kachurina N, Turcotte B, Whiteway M. Motor protein Myo5p is required to maintain the regulatory circuit controlling WOR1 expression in Candida albicans. Eukaryotic Cell. 11: 626-37. PMID 22408227 DOI: 10.1128/Ec.00021-12  0.392
2012 Yan L, Côte P, Li XX, Jiang YY, Whiteway M. PalI domain proteins of Saccharomyces cerevisiae and Candida albicans. Microbiological Research. 167: 422-32. PMID 22381911 DOI: 10.1016/J.Micres.2011.12.005  0.395
2012 Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE. Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Current Biology : Cb. 22: 461-70. PMID 22365851 DOI: 10.1016/J.Cub.2012.01.062  0.377
2011 Askew C, Sellam A, Epp E, Mallick J, Hogues H, Mullick A, Nantel A, Whiteway M. The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion. Molecular Microbiology. 79: 940-53. PMID 21299649 DOI: 10.1111/J.1365-2958.2010.07504.X  0.433
2011 Côte P, Sulea T, Dignard D, Wu C, Whiteway M. Evolutionary reshaping of fungal mating pathway scaffold proteins. Mbio. 2: e00230-10. PMID 21249169 DOI: 10.1128/Mbio.00230-10  0.407
2010 Sellam A, Hogues H, Askew C, Tebbji F, van Het Hoog M, Lavoie H, Kumamoto CA, Whiteway M, Nantel A. Experimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high-resolution tiling arrays. Genome Biology. 11: R71. PMID 20618945 DOI: 10.1186/Gb-2010-11-7-R71  0.33
2010 Rosenbach A, Dignard D, Pierce JV, Whiteway M, Kumamoto CA. Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryotic Cell. 9: 1075-86. PMID 20435697 DOI: 10.1128/Ec.00034-10  0.419
2010 Lavoie H, Hogues H, Mallick J, Sellam A, Nantel A, Whiteway M. Evolutionary tinkering with conserved components of a transcriptional regulatory network. Plos Biology. 8: e1000329. PMID 20231876 DOI: 10.1371/Journal.Pbio.1000329  0.43
2010 Epp E, Walther A, Lépine G, Leon Z, Mullick A, Raymond M, Wendland J, Whiteway M. Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis. Molecular Microbiology. 75: 1182-98. PMID 20141603 DOI: 10.1111/J.1365-2958.2009.07038.X  0.4
2010 Epp E, Vanier G, Harcus D, Lee AY, Jansen G, Hallett M, Sheppard DC, Thomas DY, Munro CA, Mullick A, Whiteway M. Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence. Plos Pathogens. 6: e1000753. PMID 20140196 DOI: 10.1371/Journal.Ppat.1000753  0.356
2010 Sellam A, Askew C, Epp E, Tebbji F, Mullick A, Whiteway M, Nantel A. Role of transcription factor CaNdt80p in cell separation, hyphal growth, and virulence in Candida albicans. Eukaryotic Cell. 9: 634-44. PMID 20097739 DOI: 10.1128/Ec.00325-09  0.455
2009 Annan RB, Lee AY, Reid ID, Sayad A, Whiteway M, Hallett M, Thomas DY. A biochemical genomics screen for substrates of Ste20p kinase enables the in silico prediction of novel substrates. Plos One. 4: e8279. PMID 20020052 DOI: 10.1371/Journal.Pone.0008279  0.335
2009 Lavoie H, Hogues H, Whiteway M. Rearrangements of the transcriptional regulatory networks of metabolic pathways in fungi. Current Opinion in Microbiology. 12: 655-63. PMID 19875326 DOI: 10.1016/J.Mib.2009.09.015  0.335
2009 Askew C, Sellam A, Epp E, Hogues H, Mullick A, Nantel A, Whiteway M. Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans. Plos Pathogens. 5: e1000612. PMID 19816560 DOI: 10.1371/Journal.Ppat.1000612  0.434
2009 Arbour M, Epp E, Hogues H, Sellam A, Lacroix C, Rauceo J, Mitchell A, Whiteway M, Nantel A. Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants. Fems Yeast Research. 9: 1070-7. PMID 19732157 DOI: 10.1111/J.1567-1364.2009.00563.X  0.321
2009 Côte P, Hogues H, Whiteway M. Transcriptional analysis of the Candida albicans cell cycle. Molecular Biology of the Cell. 20: 3363-73. PMID 19477921 DOI: 10.1091/Mbc.E09-03-0210  0.433
2009 Ma B, Pan SJ, Domergue R, Rigby T, Whiteway M, Johnson D, Cormack BP. High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation. Molecular and Cellular Biology. 29: 4067-79. PMID 19451228 DOI: 10.1128/Mcb.01461-08  0.416
2009 Sellam A, Askew C, Epp E, Lavoie H, Whiteway M, Nantel A. Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans. Molecular Biology of the Cell. 20: 2389-400. PMID 19279142 DOI: 10.1091/Mbc.E08-11-1093  0.444
2008 Lavoie H, Sellam A, Askew C, Nantel A, Whiteway M. A toolbox for epitope-tagging and genome-wide location analysis in Candida albicans. Bmc Genomics. 9: 578. PMID 19055720 DOI: 10.1186/1471-2164-9-578  0.354
2008 Dignard D, André D, Whiteway M. Heterotrimeric G-protein subunit function in Candida albicans: both the alpha and beta subunits of the pheromone response G protein are required for mating. Eukaryotic Cell. 7: 1591-9. PMID 18658257 DOI: 10.1128/Ec.00077-08  0.436
2008 Marcil A, Gadoury C, Ash J, Zhang J, Nantel A, Whiteway M. Analysis of PRA1 and its relationship to Candida albicans- macrophage interactions. Infection and Immunity. 76: 4345-58. PMID 18625733 DOI: 10.1128/Iai.00588-07  0.376
2008 Annan RB, Wu C, Waller DD, Whiteway M, Thomas DY. Rho5p is involved in mediating the osmotic stress response in Saccharomyces cerevisiae, and its activity is regulated via Msi1p and Npr1p by phosphorylation and ubiquitination. Eukaryotic Cell. 7: 1441-9. PMID 18621925 DOI: 10.1128/Ec.00120-08  0.406
2008 Lavoie H, Whiteway M. Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span. Eukaryotic Cell. 7: 1127-35. PMID 18469137 DOI: 10.1128/Ec.00330-07  0.353
2008 Huang H, Harcus D, Whiteway M. Transcript profiling of a MAP kinase pathway in C. albicans. Microbiological Research. 163: 380-93. PMID 18467082 DOI: 10.1016/J.Micres.2008.03.001  0.439
2008 Côte P, Whiteway M. The role of Candida albicans FAR1 in regulation of pheromone-mediated mating, gene expression and cell cycle arrest. Molecular Microbiology. 68: 392-404. PMID 18346117 DOI: 10.1111/J.1365-2958.2008.06158.X  0.465
2008 Hogues H, Lavoie H, Sellam A, Mangos M, Roemer T, Purisima E, Nantel A, Whiteway M. Transcription factor substitution during the evolution of fungal ribosome regulation. Molecular Cell. 29: 552-62. PMID 18342603 DOI: 10.1016/J.Molcel.2008.02.006  0.447
2008 Levitin A, Whiteway M. Drosophila innate immunity and response to fungal infections. Cellular Microbiology. 10: 1021-6. PMID 18241211 DOI: 10.1111/J.1462-5822.2008.01120.X  0.305
2007 White SJ, Rosenbach A, Lephart P, Nguyen D, Benjamin A, Tzipori S, Whiteway M, Mecsas J, Kumamoto CA. Self-regulation of Candida albicans population size during GI colonization. Plos Pathogens. 3: e184. PMID 18069889 DOI: 10.1371/Journal.Ppat.0030184  0.409
2007 Martchenko M, Levitin A, Hogues H, Nantel A, Whiteway M. Transcriptional rewiring of fungal galactose-metabolism circuitry. Current Biology : Cb. 17: 1007-13. PMID 17540568 DOI: 10.1016/J.Cub.2007.05.017  0.719
2007 Kebache S, Ash J, Annis MG, Hagan J, Huber M, Hassard J, Stewart CL, Whiteway M, Nantel A. Grb10 and active Raf-1 kinase promote Bad-dependent cell survival. The Journal of Biological Chemistry. 282: 21873-83. PMID 17535812 DOI: 10.1074/Jbc.M611066200  0.358
2007 Whiteway M, Bachewich C. Morphogenesis in Candida albicans. Annual Review of Microbiology. 61: 529-53. PMID 17506678 DOI: 10.1146/Annurev.Micro.61.080706.093341  0.389
2007 Wang J, Yan Z, Shen SH, Whiteway M, Jiang L. Expression of CaPTC7 is developmentally regulated during serum-induced morphogenesis in the human fungal pathogen Candida albicans. Canadian Journal of Microbiology. 53: 237-44. PMID 17496972 DOI: 10.1139/w06-125  0.376
2007 Lusk CP, Waller DD, Makhnevych T, Dienemann A, Whiteway M, Thomas DY, Wozniak RW. Nup53p is a target of two mitotic kinases, Cdk1p and Hrr25p. Traffic (Copenhagen, Denmark). 8: 647-60. PMID 17461799 DOI: 10.1111/J.1600-0854.2007.00559.X  0.321
2007 Levitin A, Whiteway M. The effect of prostaglandin E<inf>2</inf> on transcriptional responses of Candida albicans Microbiological Research. 162: 201-210. PMID 17433645 DOI: 10.1016/J.Micres.2007.02.001  0.447
2007 van het Hoog M, Rast TJ, Martchenko M, Grindle S, Dignard D, Hogues H, Cuomo C, Berriman M, Scherer S, Magee BB, Whiteway M, Chibana H, Nantel A, Magee PT. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biology. 8: R52. PMID 17419877 DOI: 10.1186/Gb-2007-8-4-R52  0.713
2007 Schaefer D, Côte P, Whiteway M, Bennett RJ. Barrier activity in Candida albicans mediates pheromone degradation and promotes mating. Eukaryotic Cell. 6: 907-18. PMID 17416895 DOI: 10.1128/Ec.00090-07  0.371
2007 Levitin A, Marcil A, Tettweiler G, Laforest MJ, Oberholzer U, Alarco AM, Thomas DY, Lasko P, Whiteway M. Drosophila melanogaster Thor and response to Candida albicans infection. Eukaryotic Cell. 6: 658-63. PMID 17277170 DOI: 10.1128/Ec.00346-06  0.424
2007 Dumitru R, Navarathna DH, Semighini CP, Elowsky CG, Dumitru RV, Dignard D, Whiteway M, Atkin AL, Nickerson KW. In vivo and in vitro anaerobic mating in Candida albicans. Eukaryotic Cell. 6: 465-72. PMID 17259544 DOI: 10.1128/Ec.00316-06  0.34
2007 Dignard D, El-Naggar AL, Logue ME, Butler G, Whiteway M. Identification and characterization of MFA1, the gene encoding Candida albicans a-factor pheromone. Eukaryotic Cell. 6: 487-94. PMID 17209123 DOI: 10.1128/Ec.00387-06  0.47
2007 Martchenko M, Levitin A, Whiteway M. Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs. Eukaryotic Cell. 6: 291-301. PMID 17158732 DOI: 10.1128/Ec.00183-06  0.739
2006 Oberholzer U, Nantel A, Berman J, Whiteway M. Transcript profiles of Candida albicans cortical actin patch mutants reflect their cellular defects: contribution of the Hog1p and Mkc1p signaling pathways. Eukaryotic Cell. 5: 1252-65. PMID 16896210 DOI: 10.1128/Ec.00385-05  0.431
2006 Wu M, Yu Z, Fan J, Caron A, Whiteway M, Shen SH. Functional dissection of human protease mu-calpain in cell migration using RNAi. Febs Letters. 580: 3246-56. PMID 16697376 DOI: 10.1016/J.Febslet.2006.05.003  0.318
2006 Wu C, Jansen G, Zhang J, Thomas DY, Whiteway M. Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association. Genes & Development. 20: 734-46. PMID 16543225 DOI: 10.1101/Gad.1375706  0.33
2006 Ebanks RO, Chisholm K, McKinnon S, Whiteway M, Pinto DM. Proteomic analysis of Candida albicans yeast and hyphal cell wall and associated proteins Proteomics. 6: 2147-2156. PMID 16493703 DOI: 10.1002/Pmic.200500100  0.346
2006 Dignard D, Whiteway M. SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway. Eukaryotic Cell. 5: 192-202. PMID 16400182 DOI: 10.1128/Ec.5.1.192-202.2006  0.491
2005 Kim MS, Yi MJ, Lee KH, Wagner J, Munger C, Kim YG, Whiteway M, Cygler M, Oh BH, Sacher M. Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p. Traffic (Copenhagen, Denmark). 6: 1183-95. PMID 16262728 DOI: 10.1111/J.1600-0854.2005.00352.X  0.335
2005 Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A, Inglis DO, Uhl MA, Hogues H, Berriman M, Lorenz M, Levitin A, Oberholzer U, Bachewich C, Harcus D, ... ... Whiteway M, et al. A human-curated annotation of the Candida albicans genome. Plos Genetics. 1: 36-57. PMID 16103911 DOI: 10.1371/Journal.Pgen.0010001  0.737
2005 Bachewich C, Nantel A, Whiteway M. Cell cycle arrest during S or M phase generates polarized growth via distinct signals in Candida albicans. Molecular Microbiology. 57: 942-59. PMID 16091036 DOI: 10.1111/J.1365-2958.2005.04727.X  0.364
2005 Enjalbert B, Whiteway M. Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth. Eukaryotic Cell. 4: 1203-10. PMID 16002646 DOI: 10.1128/Ec.4.7.1203-1210.2005  0.391
2005 Fan J, Whiteway M, Shen SH. Disruption of a gene encoding glycerol 3-phosphatase from Candida albicans impairs intracellular glycerol accumulation-mediated salt-tolerance. Fems Microbiology Letters. 245: 107-16. PMID 15796987 DOI: 10.1016/J.Femsle.2005.02.031  0.456
2005 Jansen G, Wu C, Schade B, Thomas DY, Whiteway M. Drag&Drop cloning in yeast. Gene. 344: 43-51. PMID 15656971 DOI: 10.1016/J.Gene.2004.10.016  0.358
2005 Bachewich C, Whiteway M. Cyclin Cln3p links G1 progression to hyphal and pseudohyphal development in Candida albicans. Eukaryotic Cell. 4: 95-102. PMID 15643065 DOI: 10.1128/Ec.4.1.95-102.2005  0.36
2004 Bhattacharjya S, Xu P, Gingras R, Shaykhutdinov R, Wu C, Whiteway M, Ni F. Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex. Journal of Molecular Biology. 344: 1071-87. PMID 15544813 DOI: 10.1016/J.Jmb.2004.09.018  0.31
2004 Oberholzer U, Iouk TL, Thomas DY, Whiteway M. Functional characterization of myosin I tail regions in Candida albicans. Eukaryotic Cell. 3: 1272-86. PMID 15470256 DOI: 10.1128/Ec.3.5.1272-1286.2004  0.339
2004 Nicholls S, Straffon M, Enjalbert B, Nantel A, Macaskill S, Whiteway M, Brown AJ. Msn2- and Msn4-like transcription factors play no obvious roles in the stress responses of the fungal pathogen Candida albicans. Eukaryotic Cell. 3: 1111-23. PMID 15470239 DOI: 10.1128/Ec.3.5.1111-1123.2004  0.372
2004 Whiteway M, Oberholzer U. Candida morphogenesis and host-pathogen interactions. Current Opinion in Microbiology. 7: 350-7. PMID 15358253 DOI: 10.1016/J.Mib.2004.06.005  0.349
2004 Harcus D, Nantel A, Marcil A, Rigby T, Whiteway M. Transcription profiling of cyclic AMP signaling in Candida albicans. Molecular Biology of the Cell. 15: 4490-9. PMID 15269278 DOI: 10.1091/Mbc.E04-02-0144  0.46
2004 Alarco AM, Marcil A, Chen J, Suter B, Thomas D, Whiteway M. Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens. Journal of Immunology (Baltimore, Md. : 1950). 172: 5622-8. PMID 15100306 DOI: 10.4049/Jimmunol.172.9.5622  0.369
2004 Lee CM, Nantel A, Jiang L, Whiteway M, Shen SH. The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans. Molecular Microbiology. 51: 691-709. PMID 14731272 DOI: 10.1111/J.1365-2958.2003.03879.X  0.493
2004 Mullick A, Elias M, Harakidas P, Marcil A, Whiteway M, Ge B, Hudson TJ, Caron AW, Bourget L, Picard S, Jovcevski O, Massie B, Thomas DY. Gene expression in HL60 granulocytoids and human polymorphonuclear leukocytes exposed to Candida albicans. Infection and Immunity. 72: 414-29. PMID 14688123 DOI: 10.1128/Iai.72.1.414-429.2004  0.429
2004 Martchenko M, Alarco AM, Harcus D, Whiteway M. Superoxide dismutases in Candida albicans: transcriptional regulation and functional characterization of the hyphal-induced SOD5 gene. Molecular Biology of the Cell. 15: 456-67. PMID 14617819 DOI: 10.1091/Mbc.E03-03-0179  0.748
2003 Panwar SL, Legrand M, Dignard D, Whiteway M, Magee PT. MFalpha1, the gene encoding the alpha mating pheromone of Candida albicans. Eukaryotic Cell. 2: 1350-60. PMID 14665468 DOI: 10.1128/Ec.2.6.1350-1360.2003  0.401
2003 Dunphy GB, Oberholzer U, Whiteway M, Zakarian RJ, Boomer I. Virulence of Candida albicans mutants toward larval Galleria mellonella (Insecta, Lepidoptera, Galleridae). Canadian Journal of Microbiology. 49: 514-24. PMID 14608387 DOI: 10.1139/W03-064  0.404
2003 Wu C, Arcand M, Jansen G, Zhong M, Iouk T, Thomas DY, Meloche S, Whiteway M. Phosphorylation of the MAPKKK regulator Ste50p in Saccharomyces cerevisiae: a casein kinase I phosphorylation site is required for proper mating function. Eukaryotic Cell. 2: 949-61. PMID 14555477 DOI: 10.1128/Ec.2.5.949-961.2003  0.353
2003 Bachewich C, Thomas DY, Whiteway M. Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth. Molecular Biology of the Cell. 14: 2163-80. PMID 12802083 DOI: 10.1091/Mbc.02-05-0076  0.397
2003 Enjalbert B, Nantel A, Whiteway M. Stress-induced gene expression in Candida albicans: absence of a general stress response. Molecular Biology of the Cell. 14: 1460-7. PMID 12686601 DOI: 10.1091/Mbc.E02-08-0546  0.322
2003 Gopalbhai K, Jansen G, Beauregard G, Whiteway M, Dumas F, Wu C, Meloche S. Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1. The Journal of Biological Chemistry. 278: 8118-25. PMID 12506122 DOI: 10.1074/Jbc.M211870200  0.326
2003 Kast C, Wang M, Whiteway M. The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter. The Journal of Biological Chemistry. 278: 6787-94. PMID 12446683 DOI: 10.1074/Jbc.M210935200  0.401
2002 Ushinsky SC, Harcus D, Ash J, Dignard D, Marcil A, Morchhauser J, Thomas DY, Whiteway M, Leberer E. CDC42 is required for polarized growth in human pathogen Candida albicans. Eukaryotic Cell. 1: 95-104. PMID 12455975 DOI: 10.1128/Ec.1.1.95-104.2002  0.414
2002 Oberholzer U, Marcil A, Leberer E, Thomas DY, Whiteway M. Myosin I is required for hypha formation in Candida albicans. Eukaryotic Cell. 1: 213-28. PMID 12455956 DOI: 10.1128/Ec.1.2.213-228.2002  0.368
2002 Nantel A, Dignard D, Bachewich C, Harcus D, Marcil A, Bouin AP, Sensen CW, Hogues H, van het Hoog M, Gordon P, Rigby T, Benoit F, Tessier DC, Thomas DY, Whiteway M. Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition. Molecular Biology of the Cell. 13: 3452-65. PMID 12388749 DOI: 10.1091/Mbc.E02-05-0272  0.408
2002 Brennan M, Thomas DY, Whiteway M, Kavanagh K. Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae. Fems Immunology and Medical Microbiology. 34: 153-7. PMID 12381467 DOI: 10.1111/J.1574-695X.2002.Tb00617.X  0.365
2002 Marcil A, Harcus D, Thomas DY, Whiteway M. Candida albicans killing by RAW 264.7 mouse macrophage cells: effects of Candida genotype, infection ratios, and gamma interferon treatment. Infection and Immunity. 70: 6319-29. PMID 12379711 DOI: 10.1128/Iai.70.11.6319-6329.2002  0.367
2002 Michel S, Ushinsky S, Klebl B, Leberer E, Thomas D, Whiteway M, Morschhäuser J. Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes. Molecular Microbiology. 46: 269-80. PMID 12366849 DOI: 10.1046/J.1365-2958.2002.03167.X  0.49
2002 Jiang L, Whiteway M, Ramos Cw, Rodriguez-Medina JR, Shen SH. The YHR076w gene encodes a type 2C protein phosphatase and represents the seventh PP2C gene in budding yeast. Febs Letters. 527: 323-5. PMID 12220683 DOI: 10.1016/S0014-5793(02)03247-7  0.422
2001 Jiang L, Whiteway M, Shen SH. A novel type 2C protein phosphatase from the human fungal pathogen Candida albicans Febs Letters. 509: 142-144. PMID 11734222 DOI: 10.1016/S0014-5793(01)03125-8  0.36
2001 Rocha CRC, Schröppel K, Harcus D, Marcil A, Dignard D, Taylor BN, Thomas DY, Whiteway M, Leberer E. Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans Molecular Biology of the Cell. 12: 3631-3643. PMID 11694594 DOI: 10.1091/Mbc.12.11.3631  0.467
2000 Whiteway M. Transcriptional control of cell type and morphogenesis in Candida albicans Current Opinion in Microbiology. 3: 582-588. PMID 11121777 DOI: 10.1016/S1369-5274(00)00144-2  0.374
2000 Schröppel K, Sprößer K, Whiteway M, Thomas DY, Röllinghoff M, Csank C. Repression of hyphal proteinase expression by the mitogen-activated protein (MAP) kinase phosphatase Cpp1p of Candida albicans is independent of the MAP kinase Cek1p Infection and Immunity. 68: 7159-7161. PMID 11083847 DOI: 10.1128/Iai.68.12.7159-7161.2000  0.389
2000 Raymond M, Dignard D, Alarco AM, Clark KL, Weber S, Whiteway M, Leberer E, Thomas DY. Molecular cloning of the CRM1 gene from Candida albicans. Yeast (Chichester, England). 16: 531-8. PMID 10790690 DOI: 10.1002/(Sici)1097-0061(200004)16:6<531::Aid-Yea543>3.0.Co;2-J  0.433
2000 Evangelista M, Klebl BM, Tong AHY, Webb BA, Leeuw T, Leberer E, Whiteway M, Thomas DY, Boone C. A role for myosin-I in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex Journal of Cell Biology. 148: 353-362. PMID 10648568 DOI: 10.1083/Jcb.148.2.353  0.338
1999 Wu C, Leberer E, Thomas DY, Whiteway M. Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae Molecular Biology of the Cell. 10: 2425-2440. PMID 10397774 DOI: 10.1091/Mbc.10.7.2425  0.344
1998 Guhad FA, Csank C, Jensen HE, Thomas DY, Whiteway M, Hau J. Reduced pathogenicity of a Candida albicans MAP kinase phosphatase (CPP1) mutant in the murine mastiffs model Apmis. 106: 1049-1055. PMID 9890266 DOI: 10.1111/J.1699-0463.1998.Tb00257.X  0.39
1998 Wu C, Leeuw T, Leberer E, Thomas DY, Whiteway M. Cell cycle- and Cln2p-Cdc28p-dependent phosphorylation of the yeast Ste20p protein kinase Journal of Biological Chemistry. 273: 28107-28115. PMID 9774429 DOI: 10.1074/Jbc.273.43.28107  0.335
1998 Guhad FA, Jensen HE, Aalbaek B, Csank C, Mohamed O, Harcus D, Thomas DY, Whiteway M, Hau J. Mitogen-activated protein kinase-defective Candida albicans is avirulent in a novel model of localized murine candidiasis Fems Microbiology Letters. 166: 135-139. PMID 9741091 DOI: 10.1111/J.1574-6968.1998.Tb13194.X  0.365
1998 Csank C, Schröppel K, Leberer E, Harcus D, Mohamed O, Meloche S, Thomas DY, Whiteway M. Roles of the Candida aibicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis Infection and Immunity. 66: 2713-2721. PMID 9596738 DOI: 10.1128/Iai.66.6.2713-2721.1998  0.484
1998 Leeuw T, Wu C, Schrag JD, Whiteway M, Thomas DY, Leberer E. Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases Nature. 391: 191-195. PMID 9428767 DOI: 10.1038/34448  0.362
1997 Csank C, Makris C, Meloche S, Schröppel K, Röllinghoff M, Dignard D, Thomas DY, Whiteway M. Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans Molecular Biology of the Cell. 8: 2539-2551. PMID 9398674 DOI: 10.1091/Mbc.8.12.2539  0.401
1997 Leberer E, Thomas DY, Whiteway M. Pheromone signalling and polarized morphogenesis in yeast Current Opinion in Genetics and Development. 7: 59-66. PMID 9024634 DOI: 10.1016/S0959-437X(97)80110-4  0.353
1995 Clark KL, Feldmann PJ, Dignard D, Larocque R, Brown AJ, Lee MG, Thomas DY, Whiteway M. Constitutive activation of the Saccharomyces cerevisiae mating response pathway by a MAP kinase kinase from Candida albicans. Molecular & General Genetics : Mgg. 249: 609-21. PMID 8544826 DOI: 10.1007/Bf00418030  0.369
1995 Wu C, Whiteway M, Thomas DY, Leberer E. Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae Journal of Biological Chemistry. 270: 15984-15992. PMID 7608157 DOI: 10.1074/Jbc.270.27.15984  0.345
1995 Leeuw T, Fourest-Lieuvin A, Wu C, Chenevert J, Clark K, Whiteway M, Thomas DY, Leberer E. Pheromone response in yeast: Association of Bem1p with proteins of the MAP kinase cascade and actin Science. 270: 1210-1213. PMID 7502048 DOI: 10.1126/Science.270.5239.1210  0.354
1994 Whiteway M, Clark KL, Leberer E, Dignard D, Thomas DY. Genetic identification of residues involved in association of α and β G-protein subunits Molecular and Cellular Biology. 14: 3223-3229. PMID 8164677 DOI: 10.1128/Mcb.14.5.3223  0.343
1994 Leberer E, Dignard D, Harcus D, Whiteway M, Thomas DY. Molecular characterization of SIG1, a Saccharomyces cerevisiae gene involved in negative regulation of G-protein-mediated signal transduction. The Embo Journal. 13: 3050-3064. DOI: 10.1002/J.1460-2075.1994.Tb06604.X  0.402
1993 Clark KL, Dignard D, Thomas DY, Whiteway M. Interactions among the Subunits of the G Protein Involved in Saccharomyces cerevisiae Mating Molecular and Cellular Biology. 13: 1-8. PMID 8417317 DOI: 10.1128/Mcb.13.1.1  0.383
1993 Leberer E, Dignard D, Harcus D, Hougan L, Whiteway M, Thomas DY. Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Farl Mgg Molecular &Amp; General Genetics. 241: 241-254. PMID 8246877 DOI: 10.1007/Bf00284675  0.451
1993 Whiteway M, Csank C, Thomas DY. Dominant Negative Selection of Heterologous Genes in Yeast Methods. 5: 110-115. DOI: 10.1006/Meth.1993.1015  0.453
1992 Whiteway M, Dignard D, Thomas DY. Dominant negative selection of heterologous genes: Isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest Proceedings of the National Academy of Sciences of the United States of America. 89: 9410-9414. PMID 1409649 DOI: 10.1073/Pnas.89.20.9410  0.461
1992 Raymond M, Gros P, Whiteway M, Thomas DY. Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene Science. 256: 232-234. PMID 1348873 DOI: 10.1126/Science.1348873  0.398
1992 Whiteway M, Dignard D, Thomas DY. Mutagenesis of Ste18, a putative G gamma subunit in the Saccharomyces cerevisiae pheromone response pathway Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 1230-1237. PMID 1297344 DOI: 10.1139/O92-169  0.394
1992 Leberer E, Dignard D, Harcus D, Thomas DY, Whiteway M. The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components. The Embo Journal. 11: 4815-4824. DOI: 10.1002/J.1460-2075.1992.Tb05587.X  0.325
1992 Leberer E, Dignard D, Hougan L, Thomas DY, Whiteway M. Dominant-negative mutants of a yeast G-protein beta subunit identify two functional regions involved in pheromone signalling. The Embo Journal. 11: 4805-4813. DOI: 10.1002/J.1460-2075.1992.Tb05586.X  0.333
1991 Dignard D, Whiteway M, Germain D, Tessier D, Thomas DY. Expression in yeast of a cDNA copy of the K2 killer toxin gene Mgg Molecular &Amp; General Genetics. 227: 127-136. PMID 2046653 DOI: 10.1007/Bf00260717  0.318
1990 Bussey H, Boone C, Zhu H, Vernet T, Whiteway M, Thomas DY. Genetic and molecular approaches to synthesis and action of the yeast killer toxin Experientia. 46: 193-200. PMID 2406163 DOI: 10.1007/Bf02027313  0.367
1990 Payette P, Gossard F, Whiteway M, Dennis M. Expression and pharmacological characterization of the human M1 muscarinic receptor in Saccharomyces cerevisiae Febs Letters. 266: 21-25. PMID 2194839 DOI: 10.1016/0014-5793(90)81496-B  0.341
1990 Whiteway M, Hougan L, Thomas DY. Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae Molecular and Cellular Biology. 10: 217-222. PMID 2104659 DOI: 10.1128/Mcb.10.1.217  0.413
1990 Finegold AA, Schafer WR, Rine J, Whiteway M, Tamanoi F. Common modifications of trimeric G proteins and ras protein: involvement of polyisoprenylation. Science (New York, N.Y.). 249: 165-9. PMID 1695391 DOI: 10.1126/Science.1695391  0.308
1989 Hougan L, Thomas DY, Whiteway M. Cloning and characterization of the SKI3 gene of Saccharomyces cerevisiae demonstrates allelism to SKI5 Current Genetics. 16: 139-143. PMID 2557163 DOI: 10.1007/Bf00391469  0.387
1989 Whiteway M, Hougan L, Dignard D, Thomas DY, Bell L, Saari GC, Grant FJ, O'Hara P, MacKay VL. The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein Cell. 56: 467-477. PMID 2536595 DOI: 10.1016/0092-8674(89)90249-3  0.378
1988 Whiteway M, Hougan L, Dignard D, Bell L, Saari G, Grant F, O'Hara P, MacKay VL, Thomas DY. Function of the STE4 and STE18 genes in mating pheromone signal transduction in Saccharomyces cerevisiae Cold Spring Harbor Symposia On Quantitative Biology. 53: 585-590. PMID 3151178 DOI: 10.1101/Sqb.1988.053.01.067  0.354
1988 Whiteway M, Hougan L, Thomas DY. Expression of MFα1 in MATa cells supersensitive to α-factor leads to self-arrest Mgg Molecular &Amp; General Genetics. 214: 85-88. PMID 3067083 DOI: 10.1007/Bf00340184  0.347
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