☰

cached image

Carole Ober - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Website:
http://www.genes.uchicago.edu/fri/oberres.html
Tree Info Grants Similar researchers Related pubs Distance to... Nearest Nobel PubMed Report error

272/404 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Clay S, Alladina J, Smith NP, Visness CM, Wood RA, O'Connor GT, Cohen RT, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Gill MA, Liu AH, Kim H, Kattan M, Bacharier LB, ... ... Ober CC, et al. Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma. The Journal of Allergy and Clinical Immunology. PMID 37944567 DOI: 10.1016/j.jaci.2023.10.023  0.324
2022 Jia G, Zhong X, Im HK, Schoettler N, Pividori M, Hogarth DK, Sperling AI, White SR, Naureckas ET, Lyttle CS, Terao C, Kamatani Y, Akiyama M, Matsuda K, Kubo M, ... ... Ober C, et al. Discerning asthma endotypes through comorbidity mapping. Nature Communications. 13: 6712. PMID 36344522 DOI: 10.1038/s41467-022-33628-8  0.594
2022 Clay SM, Schoettler N, Goldstein AM, Carbonetto P, Dapas M, Altman MC, Rosasco MG, Gern JE, Jackson DJ, Im HK, Stephens M, Nicolae DL, Ober C. Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region. Genome Medicine. 14: 55. PMID 35606880 DOI: 10.1186/s13073-022-01058-2  0.306
2021 Gereige JD, Morin A, Calatroni A, Visness CM, Wood RA, Kattan M, Bacharier LB, Becker P, Altman MC, Gern JE, Ober C, O'Connor GT. 17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 34862819 DOI: 10.1111/cea.14074  0.303
2021 Aneas I, Decker DC, Howard CL, Sobreira DR, Sakabe NJ, Blaine KM, Stein MM, Hrusch CL, Montefiori LE, Tena J, Magnaye KM, Clay SM, Gern JE, Jackson DJ, Altman MC, ... ... Ober C, et al. Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. Nature Communications. 12: 6115. PMID 34675193 DOI: 10.1038/s41467-021-26347-z  0.598
2020 Thompson EE, Dang Q, Mitchell-Handley B, Rajendran K, Ram-Mohan S, Solway J, Ober C, Krishnan R. Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma. Genome Medicine. 12: 64. PMID 32690065 DOI: 10.1186/S13073-020-00759-W  0.371
2020 Hoang TT, Sikdar S, Xu CJ, Lee MK, Cardwell J, Forno E, Imboden M, Jeong A, Madore AM, Qi C, Wang T, Bennett BD, Ward JM, Parks CG, Beane-Freeman LE, ... ... Ober C, et al. Epigenome-Wide Association Study of DNA Methylation and Adult Asthma in the Agricultural Lung Health Study. The European Respiratory Journal. PMID 32381493 DOI: 10.1183/13993003.00217-2020  0.363
2020 Ober C, McKennan CG, Magnaye KM, Altman MC, Washington C, Stanhope C, Naughton KA, Rosasco MG, Bacharier LB, Billheimer D, Gold DR, Gress L, Hartert T, Havstad S, Khurana Hershey GK, et al. Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study. The Lancet. Respiratory Medicine. 8: 482-492. PMID 32380068 DOI: 10.1016/S2213-2600(20)30011-4  0.409
2020 Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, et al. Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2. The Journal of Allergy and Clinical Immunology. PMID 32333915 DOI: 10.1016/J.Jaci.2020.04.009  0.3
2020 Vince N, Limou S, Daya M, Morii W, Rafaels N, Geffard E, Douillard V, Walencik A, Boorgula MP, Chavan S, Vergara C, Ortega VE, Wilson JG, Lange LA, Watson H, ... ... Ober C, et al. Association of HLA-DRB1*09:01 with tIgE levels among African ancestry individuals with asthma. The Journal of Allergy and Clinical Immunology. PMID 31981624 DOI: 10.1016/J.Jaci.2020.01.011  0.434
2019 Schoettler N, Hrusch CL, Blaine KM, Sperling AI, Ober C. Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. Communications Biology. 2: 411. PMID 31925217 DOI: 10.1038/s42003-019-0657-2  0.491
2019 Schoettler N, Hrusch CL, Blaine KM, Sperling AI, Ober C. Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. Communications Biology. 2: 411. PMID 31754641 DOI: 10.1038/s42003-019-0657-2  0.491
2019 Schoettler N, Rodríguez E, Weidinger S, Ober C. Advances in Asthma and Allergic Disease Genetics - Is Bigger Always Better? The Journal of Allergy and Clinical Immunology. PMID 31677964 DOI: 10.1016/J.Jaci.2019.10.023  0.41
2019 Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, ... ... Ober C, et al. Associations of autozygosity with a broad range of human phenotypes. Nature Communications. 10: 4957. PMID 31673082 DOI: 10.1038/S41467-019-12283-6  0.32
2019 Schoettler N, Ober C. Genetic architecture of moderate-to-severe asthma mirrors that of mild asthma. The Journal of Allergy and Clinical Immunology. PMID 31541629 DOI: 10.1016/J.Jaci.2019.09.003  0.353
2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, ... ... Ober C, et al. Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 10: 4082. PMID 31484942 DOI: 10.1038/S41467-019-12158-W  0.361
2019 Hrusch CL, Stein MM, Gozdz J, Holbreich M, Von Mutius E, Vercelli D, Ober C, Sperling AI. T cell phenotypes are associated with serum IgE levels in Amish and Hutterite children. The Journal of Allergy and Clinical Immunology. PMID 31401285 DOI: 10.1016/J.Jaci.2019.07.034  0.584
2019 Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR. Associations between fungal and bacterial microbiota of airways and asthma endotypes. The Journal of Allergy and Clinical Immunology. PMID 31279011 DOI: 10.1016/J.Jaci.2019.06.025  0.596
2019 Gern JE, Jackson DJ, Lemanske RF, Seroogy CM, Tachinardi U, Craven M, Hwang SY, Hamilton CM, Huggins W, O'Connor GT, Gold DR, Miller R, Kattan M, Johnson CC, Ownby D, ... ... Ober C, et al. The Children's Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population. Respiratory Research. 20: 115. PMID 31182091 DOI: 10.1186/S12931-019-1088-9  0.379
2019 Pividori M, Schoettler N, Nicolae DL, Ober C, Im HK. Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. The Lancet. Respiratory Medicine. PMID 31036433 DOI: 10.1016/S2213-2600(19)30055-4  0.396
2019 White SR, Laxman B, Naureckas ET, Hogarth DK, Solway J, Sperling AI, Ober C. Evidence for an IL-6 high asthma phenotype in asthma patients of African ancestry. The Journal of Allergy and Clinical Immunology. PMID 31029772 DOI: 10.1016/J.Jaci.2019.04.007  0.595
2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, ... ... Ober C, et al. Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 10: 880. PMID 30787307 DOI: 10.1038/S41467-019-08469-7  0.42
2019 Kogan V, Millstein J, London SJ, Ober C, White SR, Naureckas ET, Gauderman WJ, Jackson DJ, Barraza-Villarreal A, Romieu I, Raby BA, Breton CV. Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search. Human Heredity. 83: 130-152. PMID 30669148 DOI: 10.1159/000489765  0.412
2019 Kim KW, Ober C. Lessons Learned From GWAS of Asthma. Allergy, Asthma & Immunology Research. 11: 170-187. PMID 30661310 DOI: 10.4168/aair.2019.11.2.170  0.413
2018 Mozaffari SV, Stein MM, Magnaye KM, Nicolae DL, Ober C. Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions. Plos One. 13: e0203906. PMID 30204804 DOI: 10.1371/journal.pone.0203906  0.337
2018 Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, ... ... Ober C, et al. An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. The Journal of Allergy and Clinical Immunology. PMID 30201514 DOI: 10.1016/J.Jaci.2016.08.057  0.377
2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, ... ... Ober C, et al. Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nature Genetics. PMID 30013184 DOI: 10.1038/S41588-018-0157-1  0.321
2018 Stein MM, Hrusch CL, Sperling AI, Ober C. Effects of an FcγRIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies. Genes and Immunity. PMID 29977032 DOI: 10.1038/S41435-018-0038-8  0.613
2018 Thompson EE, Nicodemus-Johnson J, Kim KW, Gern JE, Jackson DJ, Lemanske RF, Ober C. Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes. Clinical Epigenetics. 10: 62. PMID 29760811 DOI: 10.1186/S13148-018-0491-2  0.334
2018 Knowles DA, Burrows CK, Blischak JD, Patterson KM, Serie DJ, Norton N, Ober C, Pritchard JK, Gilad Y. Determining the genetic basis of anthracycline-cardiotoxicity by response QTL mapping in induced cardiomyocytes. Elife. 7. PMID 29737278 DOI: 10.7554/Elife.33480  0.324
2018 Kothari PH, Qiu W, Croteau-Chonka DC, Martinez FD, Liu AH, Lemanske RF, Ober C, Krishnan JA, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, White SR, Naureckas ET, Millstein J, et al. The role of local CpG DNA methylation in mediating the 17q21 asthma-susceptibility GSDMB/ORMDL3 expression quantitative trait locus. The Journal of Allergy and Clinical Immunology. PMID 29374573 DOI: 10.1016/J.Jaci.2017.11.057  0.331
2018 Hart MW, Stover DA, Guerra V, Mozaffari SV, Ober C, Mugal CF, Kaj I. Positive selection on human gamete-recognition genes. Peerj. 6: e4259. PMID 29340252 DOI: 10.7717/peerj.4259  0.351
2018 Stein MM, Thompson EE, Schoettler N, Helling BA, Magnaye KM, Stanhope C, Igartua C, Morin A, Washington C, Nicolae D, Bønnelykke K, Ober C. A Decade of Research on the 17q12-21 Asthma Locus: Piecing Together the Puzzle. The Journal of Allergy and Clinical Immunology. PMID 29307657 DOI: 10.1016/J.Jaci.2017.12.974  0.421
2018 Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, ... ... Ober C, et al. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nature Genetics. 50: 42-53. PMID 29273806 DOI: 10.1038/S41588-017-0014-7  0.411
2017 Igartua C, Mozaffari SV, Nicolae DL, Ober C. Rare non-coding variants are associated with plasma lipid traits in a founder population. Scientific Reports. 7: 16415. PMID 29180722 DOI: 10.1038/s41598-017-16550-8  0.382
2017 Bønnelykke K, Coleman AT, Evans MD, Thorsen J, Waage J, Vissing NH, Carlsson CJ, Stokholm J, Chawes BL, Jessen LE, Fischer TK, Bochkov YA, Ober C, Lemanske RF, Jackson DJ, et al. CDHR3 Genetics and Rhinovirus C Respiratory Illnesses. American Journal of Respiratory and Critical Care Medicine. PMID 29121479 DOI: 10.1164/rccm.201705-1021OC  0.362
2017 Ober C, Sperling AI, von Mutius E, Vercelli D. Immune development and environment: lessons from Amish and Hutterite children. Current Opinion in Immunology. 48: 51-60. PMID 28843541 DOI: 10.1016/J.Coi.2017.08.003  0.584
2017 White SR, Nicodemus-Johnson J, Laxman B, Denner DR, Naureckas ET, Hogarth DK, Stern R, Minc A, Solway J, Sperling A, Ober C. Elevated levels of Soluble Human Leukocyte Antigen-G (sHLA-G) in the Airways are a Marker for a Low-inflammatory Endotype of Asthma. The Journal of Allergy and Clinical Immunology. PMID 28363527 DOI: 10.1016/J.Jaci.2017.02.031  0.606
2017 Liu YP, Rajamanikham V, Baron M, Patel S, Mathur SK, Schwantes EA, Ober C, Jackson DJ, Gern JE, Lemanske RF, Smith JA. Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leukocytes. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 28192616 DOI: 10.1111/cea.12903  0.362
2017 Igartua C, Davenport ER, Gilad Y, Nicolae DL, Pinto J, Ober C. Host genetic variation in mucosal immunity pathways influences the upper airway microbiome. Microbiome. 5: 16. PMID 28143570 DOI: 10.1186/s40168-016-0227-5  0.539
2016 DeVries A, Wlasiuk G, Miller SJ, Bosco A, Stern DA, Lohman IC, Rothers J, Jones AC, Nicodemus-Johnson J, Vasquez MM, Curtin JA, Simpson A, Custovic A, Jackson DJ, Gern JE, ... ... Ober C, et al. Epigenome-wide Analysis Links SMAD3 Methylation at Birth to Asthma in Children of Asthmatic Mothers. The Journal of Allergy and Clinical Immunology. PMID 28011059 DOI: 10.1016/J.Jaci.2016.10.041  0.341
2016 Papachristou C, Ober C, Abney M. A LASSO penalized regression approach for genome-wide association analyses using related individuals: application to the Genetic Analysis Workshop 19 simulated data. Bmc Proceedings. 10: 221-226. PMID 27980640 DOI: 10.1186/s12919-016-0034-9  0.308
2016 Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. Jci Insight. 1: e90151. PMID 27942592 DOI: 10.1172/Jci.Insight.90151  0.637
2016 Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, ... ... Ober C, et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 7: 12522. PMID 27725671 DOI: 10.1038/Ncomms12522  0.386
2016 Lamont RE, Beaulieu CL, Bernier FP, Sparkes R, Innes AM, Jackel-Cram C, Ober C, Parboosingh JS, Lemire EG. A novel NDUFS4 frameshift mutation causes Leigh disease in the Hutterite population. American Journal of Medical Genetics. Part A. PMID 27671926 DOI: 10.1002/Ajmg.A.37983  0.316
2016 Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, ... ... Ober C, et al. Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. The New England Journal of Medicine. 375: 411-21. PMID 27518660 DOI: 10.1056/Nejmoa1508749  0.613
2016 Croteau-Chonka DC, Qiu W, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Gilliland FD, Millstein J, Gauderman WJ, Ober C, Krishnan JA, White SR, Naureckas ET, Nicolae DL, Barnes KC, et al. Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control. American Journal of Respiratory and Critical Care Medicine. PMID 27494826 DOI: 10.1164/Rccm.201601-0107Oc  0.361
2016 Burrows CK, Kosova G, Herman C, Patterson K, Hartmann KE, Velez Edwards DR, Stephenson MD, Lynch VJ, Ober C. Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes. Plos Genetics. 12: e1005858. PMID 27447835 DOI: 10.1371/Journal.Pgen.1005858  0.79
2016 Triggs-Raine B, Dyck T, Boycott KM, Innes AM, Ober C, Parboosingh JS, Botkin A, Greenberg CR, Spriggs EL. Development of a diagnostic DNA chip to screen for 30 autosomal recessive disorders in the Hutterite population. Molecular Genetics & Genomic Medicine. 4: 312-21. PMID 27247959 DOI: 10.1002/mgg3.206  0.313
2016 Goodrich JK, Davenport ER, Beaumont M, Jackson MA, Knight R, Ober C, Spector TD, Bell JT, Clark AG, Ley RE. Genetic Determinants of the Gut Microbiome in UK Twins. Cell Host & Microbe. 19: 731-43. PMID 27173935 DOI: 10.1016/J.Chom.2016.04.017  0.359
2016 Gozdz J, Holbreich M, Metwali N, Thorne PS, Sperling AI, Martinez FD, Ober C, von Mutius E, Vercelli D. Amish and Hutterite Environmental Farm Products Have Opposite Effects on Experimental Models of Asthma. Annals of the American Thoracic Society. 13: S99. PMID 27027969 DOI: 10.1513/Annalsats.201509-581Mg  0.582
2016 Ober C. Asthma Genetics in the Post-GWAS Era. Annals of the American Thoracic Society. 13: S85-90. PMID 27027959 DOI: 10.1513/AnnalsATS.201507-459MG  0.438
2016 Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, et al. Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma. Annals of the American Thoracic Society. 13: S104-S105. PMID 27027945 DOI: 10.1513/Annalsats.201510-681Mg  0.349
2016 Igartua C, Davenport ER, Chupp GL, Elias JA, Gilad Y, Ober C, Pinto JM. Nasal Microbiome Composition Is Associated with Chitotriosidase (Chit1) Activity in Adult Hutterites. Annals of the American Thoracic Society. 13: S100-1. PMID 27027937 DOI: 10.1513/Annalsats.201508-521Mg  0.457
2016 Bønnelykke K, Ober C. Leveraging gene-environment interactions and endotypes for asthma gene discovery. The Journal of Allergy and Clinical Immunology. 137: 667-79. PMID 26947980 DOI: 10.1016/j.jaci.2016.01.006  0.412
2016 Cusanovich DA, Caliskan M, Billstrand C, Michelini K, Chavarria C, De Leon S, Mitrano A, Lewellyn N, Elias JA, Chupp GL, Lang RM, Shah SJ, DeCara JM, Gilad Y, Ober C. Integrated Analyses of Gene Expression and Genetic Association Studies in a Founder Population. Human Molecular Genetics. PMID 26931462 DOI: 10.1093/Hmg/Ddw061  0.626
2015 Davenport ER, Cusanovich DA, Michelini K, Barreiro LB, Ober C, Gilad Y. Genome-Wide Association Studies of the Human Gut Microbiota. Plos One. 10: e0140301. PMID 26528553 DOI: 10.1371/Journal.Pone.0140301  0.39
2015 Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, ... ... Ober C, et al. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics. 47: 1449-56. PMID 26482879 DOI: 10.1038/Ng.3424  0.399
2015 Nicodemus-Johnson J, Naughton KA, Sudi J, Hogarth K, Naurekas ET, Nicolae DL, Sperling AI, Solway J, White SR, Ober C. Genome-wide Methylation Study Identifies an IL-13 Induced Epigenetic Signature in Asthmatic Airways. American Journal of Respiratory and Critical Care Medicine. PMID 26474238 DOI: 10.1164/Rccm.201506-1243Oc  0.598
2015 Loisel DA, Du G, Ahluwalia TS, Tisler CJ, Evans MD, Myers RA, Gangnon RE, Møller EK, Bønnelykke K, Bisgaard H, Jackson DJ, Lemanske RF, Nicolae DL, Gern JE, Ober C. Genetic associations with viral respiratory illnesses and asthma control in children. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 26399222 DOI: 10.1111/Cea.12642  0.32
2015 Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, et al. Future Research Directions in Asthma: An NHLBI Working Group Report. American Journal of Respiratory and Critical Care Medicine. PMID 26305520 DOI: 10.1164/rccm.201505-0963WS  0.33
2015 Loucks CM, Parboosingh JS, Shaheen R, Bernier FP, McLeod DR, Seidahmed MZ, Puffenberger EG, Ober C, Hegele RA, Boycott KM, Alkuraya FS, Innes AM. Matching Two Independent Cohorts Validates DPH1 as a Gene Responsible for Autosomal Recessive Intellectual Disability with Short Stature, Craniofacial, and Ectodermal Anomalies. Human Mutation. 36: 1015-9. PMID 26220823 DOI: 10.1002/humu.22843  0.354
2015 Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen TT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, ... ... Ober C, et al. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nature Cell Biology. PMID 26167768 DOI: 10.1038/Ncb3201  0.353
2015 Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, ... ... Ober C, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 523: 459-62. PMID 26131930 DOI: 10.1038/Nature14618  0.368
2015 Çal??kan M, Baker SW, Gilad Y, Ober C. Host genetic variation influences gene expression response to rhinovirus infection. Plos Genetics. 11: e1005111. PMID 25874939 DOI: 10.1371/Journal.Pgen.1005111  0.355
2015 Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, et al. Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma. American Journal of Respiratory and Critical Care Medicine. 191: 1116-25. PMID 25763605 DOI: 10.1164/Rccm.201408-1440Oc  0.368
2015 Livne OE, Han L, Alkorta-Aranburu G, Wentworth-Sheilds W, Abney M, Ober C, Nicolae DL. PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population. Plos Computational Biology. 11: e1004139. PMID 25735005 DOI: 10.1371/Journal.Pcbi.1004139  0.393
2015 Gao Z, Waggoner D, Stephens M, Ober C, Przeworski M. An estimate of the average number of recessive lethal mutations carried by humans. Genetics. 199: 1243-54. PMID 25697177 DOI: 10.1534/Genetics.114.173351  0.337
2015 Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, ... ... Ober C, et al. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nature Communications. 6: 5965. PMID 25591454 DOI: 10.1038/Ncomms6965  0.428
2015 Kosova G, Stephenson MD, Lynch VJ, Ober C. Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy loss. Human Reproduction (Oxford, England). 30: 519-29. PMID 25586782 DOI: 10.1093/Humrep/Deu355  0.749
2015 Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, ... ... Ober C, et al. Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos. The Journal of Allergy and Clinical Immunology. 135: 1502-10. PMID 25488688 DOI: 10.1016/J.Jaci.2014.10.033  0.338
2015 Alkorta-Aranburu G, Igartua C, Davenport ER, Naughton K, Watanabe S, Gilad Y, Lemanske RF, Mauger DM, Ober C, Jackson DJ, Pinto JM. Decrease in Diversity of Nasal Microbiota during Wheezing Episodes in Preschool Children Journal of Allergy and Clinical Immunology. 135: AB274. DOI: 10.1016/J.Jaci.2014.12.1835  0.52
2015 Rafaels NM, Johnston HR, Huang L, Chavan S, Wilson JG, Williams LK, Ware LB, Ober C, Meyers DA, Hartert TV, Foreman M, Ford JG, Burchard EG, Bleecker ER, Taub M, et al. How Well Does Whole Genome Sequencing Improve Ability to Detect Association with Asthma in Candidate Genes Compared to Existing GWAS Platforms in African American Populations? Journal of Allergy and Clinical Immunology. 135: AB164. DOI: 10.1016/J.Jaci.2014.12.1473  0.392
2015 Masuko H, Rafaels NM, Huang L, Chavan S, Wilson JG, Williams LK, Ware LB, Ober C, Meyers DA, Hartert TV, Foreman M, Ford JG, Burchard EG, Bleecker ER, Dunston G, et al. Imputation from 328 African Ancestry Genomes Reveals New Associations with Asthma in DPP10 Journal of Allergy and Clinical Immunology. 135: AB162. DOI: 10.1016/J.Jaci.2014.12.1469  0.363
2014 Hansel NN, Paré PD, Rafaels N, Sin D, Sandford A, Daley D, Vergara C, Huang L, Elliott WM, Pascoe CD, Arsenault BA, Postma DS, Boezen HM, Bossé Y, van den Berge M, ... ... Ober C, et al. Genome Wide Association Study Identifies Novel Loci Associated with Airway Responsiveness in COPD. American Journal of Respiratory Cell and Molecular Biology. PMID 25514360 DOI: 10.1165/Rcmb.2014-0198Oc  0.395
2014 Çal??kan M, Pritchard JK, Ober C, Gilad Y. The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines. Plos One. 9: e107166. PMID 25192014 DOI: 10.1371/Journal.Pone.0107166  0.337
2014 Campbell CD, Mohajeri K, Malig M, Hormozdiari F, Nelson B, Du G, Patterson KM, Eng C, Torgerson DG, Hu D, Herman C, Chong JX, Ko A, O'Roak BJ, Krumm N, ... ... Ober C, et al. Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. Plos One. 9: e104396. PMID 25116239 DOI: 10.1371/Journal.Pone.0104396  0.717
2014 Bunyavanich S, Schadt EE, Himes BE, Lasky-Su J, Qiu W, Lazarus R, Ziniti JP, Cohain A, Linderman M, Torgerson DG, Eng CS, Pino-Yanes M, Padhukasahasram B, Yang JJ, Mathias RA, ... ... Ober C, et al. Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. Bmc Medical Genomics. 7: 48. PMID 25085501 DOI: 10.1186/1755-8794-7-48  0.397
2014 Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Avila L, Soto-Quiros M, Barraza-Villareal A, ... ... Ober C, et al. A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. The Journal of Allergy and Clinical Immunology. 134: 1153-62. PMID 24934276 DOI: 10.1016/J.Jaci.2014.04.011  0.439
2014 Myers RA, Scott NM, Gauderman WJ, Qiu W, Mathias RA, Romieu I, Levin AM, Pino-Yanes M, Graves PE, Villarreal AB, Beaty TH, Carey VJ, Croteau-Chonka DC, del Rio Navarro B, Edlund C, ... ... Ober C, et al. Genome-wide interaction studies reveal sex-specific asthma risk alleles. Human Molecular Genetics. 23: 5251-9. PMID 24824216 DOI: 10.1093/Hmg/Ddu222  0.425
2014 Anderson RL, Murray K, Chong JX, Ouwenga R, Antillon M, Chen P, Diaz de Leon L, Swoboda KJ, Lester LA, Das S, Ober C, Waggoner DJ. Disclosure of genetic research results to members of a founder population. Journal of Genetic Counseling. 23: 984-91. PMID 24777552 DOI: 10.1007/S10897-014-9721-8  0.629
2014 van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, ... ... Ober C, et al. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. The Journal of Allergy and Clinical Immunology. 134: 46-55. PMID 24315451 DOI: 10.1016/J.Jaci.2013.08.053  0.343
2014 Kosova G, Hotaling JM, Ohlander S, Niederberger C, Prins GS, Ober C. Variants in DPF3 and DSCAML1 are associated with sperm morphology. Journal of Assisted Reproduction and Genetics. 31: 131-7. PMID 24271036 DOI: 10.1007/S10815-013-0140-9  0.774
2013 Gerull B, Kirchner F, Chong JX, Tagoe J, Chandrasekharan K, Strohm O, Waggoner D, Ober C, Duff HJ. Homozygous founder mutation in desmocollin-2 (DSC2) causes arrhythmogenic cardiomyopathy in the Hutterite population. Circulation. Cardiovascular Genetics. 6: 327-36. PMID 23863954 DOI: 10.1161/Circgenetics.113.000097  0.622
2013 Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, ... ... Ober C, et al. Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. American Journal of Human Genetics. 93: 181-90. PMID 23830518 DOI: 10.1016/J.Ajhg.2013.05.028  0.631
2013 Beaulieu CL, Huang L, Innes AM, Akimenko MA, Puffenberger EG, Schwartz C, Jerry P, Ober C, Hegele RA, McLeod DR, Schwartzentruber J, Majewski J, Bulman DE, Parboosingh JS, et al. Intellectual disability associated with a homozygous missense mutation in THOC6. Orphanet Journal of Rare Diseases. 8: 62. PMID 23621916 DOI: 10.1186/1750-1172-8-62  0.337
2013 Lopes AM, Aston KI, Thompson E, Carvalho F, Gonçalves J, Huang N, Matthiesen R, Noordam MJ, Quintela I, Ramu A, Seabra C, Wilfert AB, Dai J, Downie JM, Fernandes S, ... ... Ober C, et al. Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. Plos Genetics. 9: e1003349. PMID 23555275 DOI: 10.1371/Journal.Pgen.1003349  0.38
2013 Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C. Maternal asthma and microRNA regulation of soluble HLA-G in the airway. The Journal of Allergy and Clinical Immunology. 131: 1496-503. PMID 23534973 DOI: 10.1016/J.Jaci.2013.01.037  0.613
2013 Calışkan M, Bochkov YA, Kreiner-Møller E, Bønnelykke K, Stein MM, Du G, Bisgaard H, Jackson DJ, Gern JE, Lemanske RF, Nicolae DL, Ober C. Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. The New England Journal of Medicine. 368: 1398-407. PMID 23534543 DOI: 10.1056/Nejmoa1211592  0.405
2013 Melén E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, ... ... Ober C, et al. Genome-wide association study of body mass index in 23 000 individuals with and without asthma. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 43: 463-74. PMID 23517042 DOI: 10.1111/Cea.12054  0.355
2013 Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, ... ... Ober C, et al. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. Plos One. 8: e56179. PMID 23457522 DOI: 10.1371/Journal.Pone.0056179  0.429
2013 Thompson EE, Myers RA, Du G, Aydelotte TM, Tisler CJ, Stern DA, Evans MD, Graves PE, Jackson DJ, Martinez FD, Gern JE, Wright AL, Lemanske RF, Ober C. Maternal microchimerism protects against the development of asthma. The Journal of Allergy and Clinical Immunology. 132: 39-44. PMID 23434286 DOI: 10.1016/J.Jaci.2012.12.1575  0.376
2013 Levin AM, Mathias RA, Huang L, Roth LA, Daley D, Myers RA, Himes BE, Romieu I, Yang M, Eng C, Park JE, Zoratti K, Gignoux CR, Torgerson DG, Galanter JM, ... ... Ober C, et al. A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. The Journal of Allergy and Clinical Immunology. 131: 1176-84. PMID 23146381 DOI: 10.1016/J.Jaci.2012.10.002  0.428
2013 Loisel DA, Billstrand C, Murray K, Patterson K, Chaiworapongsa T, Romero R, Ober C. The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women. Molecular Human Reproduction. 19: 144-52. PMID 23002110 DOI: 10.1093/Molehr/Gas041  0.381
2013 Hotaling J, Kosova G, Ohlander S, Niederberger C, Prins GS, Ober C. 2033 GENOME-WIDE ASSOCIATION STUDY IDENTIFIES CANDIDATE GENES FOR ABNORMAL SPERM MORPHOLOGY IN TWO COHORTS OF MEN Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.2452  0.777
2013 Hedjoudje A, Huang L, Rafaels NM, Vergara CI, Taub M, Ruczinski I, Ober C, Burchard EG, Beaty TH, Vercelli D, Barnes KC, Mathias RA. Whole Genome Sequence Reveals a Haplotype Conferring Protection From Asthma Common to Subjects of European and African Ancestry Journal of Allergy and Clinical Immunology. 131: AB54. DOI: 10.1016/J.Jaci.2012.12.874  0.351
2012 Ségurel L, Thompson EE, Flutre T, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M. The ABO blood group is a trans-species polymorphism in primates. Proceedings of the National Academy of Sciences of the United States of America. 109: 18493-8. PMID 23091028 DOI: 10.1073/Pnas.1210603109  0.328
2012 Myers RA, Himes BE, Gignoux CR, Yang JJ, Gauderman WJ, Rebordosa C, Xie J, Torgerson DG, Levin AM, Baurley J, Graves PE, Mathias RA, Romieu I, Roth LA, Conti D, ... ... Ober C, et al. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. The Journal of Allergy and Clinical Immunology. 130: 1294-301. PMID 23040885 DOI: 10.1016/J.Jaci.2012.07.054  0.398
2012 Campbell CD, Chong JX, Malig M, Ko A, Dumont BL, Han L, Vives L, O'Roak BJ, Sudmant PH, Shendure J, Abney M, Ober C, Eichler EE. Estimating the human mutation rate using autozygosity in a founder population. Nature Genetics. 44: 1277-81. PMID 23001126 DOI: 10.1038/Ng.2418  0.641
2012 Chong JX, Ouwenga R, Anderson RL, Waggoner DJ, Ober C. A population-based study of autosomal-recessive disease-causing mutations in a founder population. American Journal of Human Genetics. 91: 608-20. PMID 22981120 DOI: 10.1016/J.Ajhg.2012.08.007  0.645
2012 Li X, Ampleford EJ, Howard TD, Moore WC, Torgerson DG, Li H, Busse WW, Castro M, Erzurum SC, Israel E, Nicolae DL, Ober C, Wenzel SE, Hawkins GA, Bleecker ER, et al. Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. The Journal of Allergy and Clinical Immunology. 130: 861-8.e7. PMID 22694930 DOI: 10.1097/01.Wox.0000411861.60664.A3  0.315
2012 Jassem RM, Shani WS, Loisel DA, Sharief M, Billstrand C, Ober C. HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq. Human Immunology. 73: 811-7. PMID 22651916 DOI: 10.1016/J.Humimm.2012.05.009  0.369
2012 Kosova G, Scott NM, Niederberger C, Prins GS, Ober C. Genome-wide association study identifies candidate genes for male fertility traits in humans. American Journal of Human Genetics. 90: 950-61. PMID 22633400 DOI: 10.1016/J.Ajhg.2012.04.016  0.789
2012 Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, ... ... Ober C, et al. Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. The Journal of Allergy and Clinical Immunology. 130: 622-629.e9. PMID 22607992 DOI: 10.1016/J.Jaci.2012.03.045  0.44
2012 Thornton T, Zhang Q, Cai X, Ober C, McPeek MS. XM: association testing on the X-chromosome in case-control samples with related individuals. Genetic Epidemiology. 36: 438-50. PMID 22552845 DOI: 10.1002/Gepi.21638  0.387
2012 Welt CK, Styrkarsdottir U, Ehrmann DA, Thorleifsson G, Arason G, Gudmundsson JA, Ober C, Rosenfield RL, Saxena R, Thorsteinsdottir U, Crowley WF, Stefansson K. Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. The Journal of Clinical Endocrinology and Metabolism. 97: E1342-7. PMID 22547425 DOI: 10.1210/jc.2011-3478  0.305
2012 Loucks C, Parboosingh JS, Chong JX, Ober C, Siu VM, Hegele RA, Rupar CA, McLeod DR, Pinto A, Chudley AE, Innes AM. A shared founder mutation underlies restrictive dermopathy in Old Colony (Dutch-German) Mennonite and Hutterite patients in North America. American Journal of Medical Genetics. Part A. 158: 1229-32. PMID 22495976 DOI: 10.1002/Ajmg.A.35302  0.618
2012 Uricchio LH, Chong JX, Ross KD, Ober C, Nicolae DL. Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals. Genetic Epidemiology. 36: 312-9. PMID 22460724 DOI: 10.1002/Gepi.21623  0.673
2012 Meyer WK, Arbeithuber B, Ober C, Ebner T, Tiemann-Boege I, Hudson RR, Przeworski M. Evaluating the evidence for transmission distortion in human pedigrees. Genetics. 191: 215-32. PMID 22377632 DOI: 10.1534/Genetics.112.139576  0.373
2012 Perry GH, Xue Y, Smith RS, Meyer WK, Calışkan M, Yanez-Cuna O, Lee AS, Gutiérrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Evolutionary genetics of the human Rh blood group system. Human Genetics. 131: 1205-16. PMID 22367406 DOI: 10.1007/S00439-012-1147-5  0.378
2012 Torgerson DG, Capurso D, Mathias RA, Graves PE, Hernandez RD, Beaty TH, Bleecker ER, Raby BA, Meyers DA, Barnes KC, Weiss ST, Martinez FD, Nicolae DL, Ober C. Resequencing candidate genes implicates rare variants in asthma susceptibility. American Journal of Human Genetics. 90: 273-81. PMID 22325360 DOI: 10.1016/J.Ajhg.2012.01.008  0.439
2012 Cusanovich DA, Billstrand C, Zhou X, Chavarria C, De Leon S, Michelini K, Pai AA, Ober C, Gilad Y. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Human Molecular Genetics. 21: 2111-23. PMID 22286170 DOI: 10.1093/Hmg/Dds021  0.467
2011 Huang L, Szymanska K, Jensen VL, Janecke AR, Innes AM, Davis EE, Frosk P, Li C, Willer JR, Chodirker BN, Greenberg CR, McLeod DR, Bernier FP, Chudley AE, Müller T, ... ... Ober C, et al. TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. American Journal of Human Genetics. 89: 713-30. PMID 22152675 DOI: 10.1016/J.Ajhg.2011.11.005  0.31
2011 Motika CA, Papachristou C, Abney M, Lester LA, Ober C. Rising prevalence of asthma is sex-specific in a US farming population. The Journal of Allergy and Clinical Immunology. 128: 774-9. PMID 21840584 DOI: 10.1016/j.jaci.2011.06.046  0.353
2011 Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, ... ... Ober C, et al. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nature Genetics. 43: 887-92. PMID 21804549 DOI: 10.1038/Ng.888  0.43
2011 Loisel DA, Tan Z, Tisler CJ, Evans MD, Gangnon RE, Jackson DJ, Gern JE, Lemanske RF, Ober C. IFNG genotype and sex interact to influence the risk of childhood asthma. The Journal of Allergy and Clinical Immunology. 128: 524-31. PMID 21798578 DOI: 10.1016/J.Jaci.2011.06.016  0.356
2011 Ober C, Yao TC. The genetics of asthma and allergic disease: a 21st century perspective. Immunological Reviews. 242: 10-30. PMID 21682736 DOI: 10.1111/j.1600-065X.2011.01029.x  0.418
2011 Topper S, Ober C, Das S. Exome sequencing and the genetics of intellectual disability. Clinical Genetics. 80: 117-26. PMID 21627642 DOI: 10.1111/j.1399-0004.2011.01720.x  0.346
2011 Chong JX, Oktay AA, Dai Z, Swoboda KJ, Prior TW, Ober C. A common spinal muscular atrophy deletion mutation is present on a single founder haplotype in the US Hutterites. European Journal of Human Genetics : Ejhg. 19: 1045-51. PMID 21610747 DOI: 10.1038/Ejhg.2011.85  0.673
2011 Papachristou C, Ober C, Abney M. Genetic variance components estimation for binary traits using multiple related individuals. Genetic Epidemiology. 35: 291-302. PMID 21465547 DOI: 10.1002/gepi.20577  0.314
2011 Caliskan M, Cusanovich DA, Ober C, Gilad Y. The effects of EBV transformation on gene expression levels and methylation profiles. Human Molecular Genetics. 20: 1643-52. PMID 21289059 DOI: 10.1093/Hmg/Ddr041  0.586
2011 Ober C, Vercelli D. Gene-environment interactions in human disease: nuisance or opportunity? Trends in Genetics : Tig. 27: 107-15. PMID 21216485 DOI: 10.1016/J.Tig.2010.12.004  0.368
2011 Çalışkan M, Chong JX, Uricchio L, Anderson R, Chen P, Sougnez C, Garimella K, Gabriel SB, dePristo MA, Shakir K, Matern D, Das S, Waggoner D, Nicolae DL, Ober C. Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13. Human Molecular Genetics. 20: 1285-9. PMID 21212097 DOI: 10.1093/Hmg/Ddq569  0.652
2010 Sun X, Ma SF, Wade MS, Flores C, Pino-Yanes M, Moitra J, Ober C, Kittles R, Husain AN, Ford JG, Garcia JG. Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility. The Journal of Allergy and Clinical Immunology. 126: 241-9, 249.e1-3. PMID 20624651 DOI: 10.1016/J.Jaci.2010.04.036  0.421
2010 Ober C, Butte AJ, Elias JA, Lusis AJ, Gan W, Banks-Schlegel S, Schwartz D. Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. American Journal of Respiratory and Critical Care Medicine. 182: 732-7. PMID 20558629 DOI: 10.1164/Rccm.201002-0180Pp  0.342
2010 Kosova G, Pickrell JK, Kelley JL, McArdle PF, Shuldiner AR, Abney M, Ober C. The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate. Plos Genetics. 6: e1000974. PMID 20532200 DOI: 10.1371/Journal.Pgen.1000974  0.789
2010 White SR, Loisel DA, McConville JF, Stern R, Tu Y, Marroquin BA, Noth I, Ober C. Levels of soluble human leukocyte antigen-G are increased in asthmatic airways. The European Respiratory Journal. 35: 925-7. PMID 20356990 DOI: 10.1183/09031936.00164809  0.398
2010 Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science (New York, N.Y.). 327: 836-40. PMID 20044539 DOI: 10.1126/Science.1183439  0.323
2010 Pichler I, Fuchsberger C, Platzer C, CaliÅŸkan M, Marroni F, Pramstaller PP, Ober C. Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes. European Journal of Human Genetics : Ejhg. 18: 463-70. PMID 19844259 DOI: 10.1038/Ejhg.2009.172  0.375
2010 Thompson EE, Haller G, Pinto JM, Sun Y, Zelano B, Jacob S, McClintock MK, Nicolae DL, Ober C. Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors. Human Immunology. 71: 100-3. PMID 19833159 DOI: 10.1016/J.Humimm.2009.10.004  0.548
2010 Kosova G, Abney M, Ober C. Colloquium papers: Heritability of reproductive fitness traits in a human population. Proceedings of the National Academy of Sciences of the United States of America. 107: 1772-8. PMID 19822755 DOI: 10.1073/Pnas.0906196106  0.764
2010 Thompson EE, Sun Y, Nicolae D, Ober C. Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans. Genetic Epidemiology. 34: 133-9. PMID 19697328 DOI: 10.1002/Gepi.20442  0.427
2009 Haller G, Torgerson DG, Ober C, Thompson EE. Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. The Journal of Allergy and Clinical Immunology. 124: 1204-9.e9. PMID 19910025 DOI: 10.1016/J.Jaci.2009.09.013  0.389
2009 Ober C, Chupp GL. The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases. Current Opinion in Allergy and Clinical Immunology. 9: 401-8. PMID 19644363 DOI: 10.1097/ACI.0b013e3283306533  0.372
2009 Nicolae DL, Ober C. (Too) great expectations: the challenges in replicating asthma disease genes. American Journal of Respiratory and Critical Care Medicine. 179: 1078-9. PMID 19498061 DOI: 10.1164/rccm.200903-0456ED  0.468
2009 Bellenguez C, Ober C, Bourgain C. Linkage analysis with dense SNP maps in isolated populations. Human Heredity. 68: 87-97. PMID 19365135 DOI: 10.1159/000212501  0.358
2009 Ober C, Nord AS, Thompson EE, Pan L, Tan Z, Cusanovich D, Sun Y, Nicolae R, Edelstein C, Schneider DH, Billstrand C, Pfaffinger D, Phillips N, Anderson RL, Philips B, et al. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. Journal of Lipid Research. 50: 798-806. PMID 19124843 DOI: 10.1194/Jlr.M800515-Jlr200  0.369
2009 Bellenguez C, Ober C, Bourgain C. A multiple splitting approach to linkage analysis in large pedigrees identifies a linkage to asthma on chromosome 12. Genetic Epidemiology. 33: 207-16. PMID 18839415 DOI: 10.1002/gepi.20371  0.352
2008 Ober C, Loisel DA, Gilad Y. Sex-specific genetic architecture of human disease. Nature Reviews. Genetics. 9: 911-22. PMID 19002143 DOI: 10.1038/Nrg2415  0.363
2008 Pinto JM, Hayes MG, Schneider D, Naclerio RM, Ober C. A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q. The Laryngoscope. 118: 2067-72. PMID 18622306 DOI: 10.1097/MLG.0b013e3181805147  0.494
2008 Ma SF, Flores C, Wade MS, Dudek SM, Nicolae DL, Ober C, Garcia JG. A common cortactin gene variation confers differential susceptibility to severe asthma. Genetic Epidemiology. 32: 757-66. PMID 18521921 DOI: 10.1002/gepi.20343  0.449
2008 Nolan DK, Chen P, Das S, Ober C, Waggoner D. Fine mapping of a locus for nonsyndromic mental retardation on chromosome 19p13. American Journal of Medical Genetics. Part A. 146: 1414-22. PMID 18446860 DOI: 10.1002/ajmg.a.32307  0.737
2008 Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF, Nicolae DL, Elias JA, et al. Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. The New England Journal of Medicine. 358: 1682-91. PMID 18403759 DOI: 10.1056/Nejmoa0708801  0.349
2008 Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M, Stacey SN, Kostic J, Kristinsson KT, Birgisdottir B, ... ... Ober C, et al. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nature Genetics. 40: 281-3. PMID 18264098 DOI: 10.1038/Ng.89  0.313
2008 Pinto JM, Thanaviratananich S, Hayes MG, Naclerio RM, Ober C. A genome-wide screen for hyposmia susceptibility Loci. Chemical Senses. 33: 319-29. PMID 18245794 DOI: 10.1093/chemse/bjm092  0.549
2008 Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (New York, N.Y.). 319: 1395-8. PMID 18239090 DOI: 10.1126/Science.1151851  0.326
2008 Gallego Romero I, Ober C. CFTR mutations and reproductive outcomes in a population isolate. Human Genetics. 122: 583-8. PMID 17901983 DOI: 10.1007/s00439-007-0432-1  0.333
2007 Tan Z, Randall G, Fan J, Camoretti-Mercado B, Brockman-Schneider R, Pan L, Solway J, Gern JE, Lemanske RF, Nicolae D, Ober C. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. American Journal of Human Genetics. 81: 829-34. PMID 17847008 DOI: 10.1016/J.Ajhg.2007.12.008  0.37
2007 Gudmundsson J, Sulem P, Steinthorsdottir V, Bergthorsson JT, Thorleifsson G, Manolescu A, Rafnar T, Gudbjartsson D, Agnarsson BA, Baker A, Sigurdsson A, Benediktsdottir KR, Jakobsdottir M, Blondal T, Stacey SN, ... ... Ober C, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nature Genetics. 39: 977-83. PMID 17603485 DOI: 10.1038/Ng2062  0.315
2007 Pluzhnikov A, Nolan DK, Tan Z, McPeek MS, Ober C. Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness. American Journal of Human Genetics. 81: 165-9. PMID 17564973 DOI: 10.1086/518446  0.726
2007 Thompson EE, Pan L, Ostrovnaya I, Weiss LA, Gern JE, Lemanske RF, Nicolae DL, Ober C. Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life. The Journal of Allergy and Clinical Immunology. 119: 1423-9. PMID 17556058 DOI: 10.1016/J.Jaci.2007.03.029  0.375
2007 Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D, Helgason A, Rafnar T, Bergthorsson JT, Agnarsson BA, Baker A, Sigurdsson A, Benediktsdottir KR, Jakobsdottir M, Xu J, Blondal T, ... ... Ober C, et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nature Genetics. 39: 631-7. PMID 17401366 DOI: 10.1038/Ng1999  0.333
2007 Pan L, Ober C, Abney M. Heritability estimation of sex-specific effects on human quantitative traits. Genetic Epidemiology. 31: 338-47. PMID 17323368 DOI: 10.1002/gepi.20214  0.334
2007 Wittke-Thompson JK, Ambrose N, Yairi E, Roe C, Cook EH, Ober C, Cox NJ. Genetic studies of stuttering in a founder population. Journal of Fluency Disorders. 32: 33-50. PMID 17276504 DOI: 10.1016/J.Jfludis.2006.12.002  0.352
2007 Flores C, Ma SF, Maresso K, Ober C, Garcia JG. A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans. Genetic Epidemiology. 31: 296-305. PMID 17266121 DOI: 10.1002/gepi.20210  0.428
2007 Pinto J, Sahin-Yilmaz A, Baroody F, deTineo M, Elwany S, Ober C, Naclerio R. The Ability of the Nose to Warm and Humidify Inspired Air is Heritable Journal of Allergy and Clinical Immunology. 119: S314. DOI: 10.1016/j.jaci.2006.12.600  0.365
2006 Kurz T, Hoffjan S, Hayes MG, Schneider D, Nicolae R, Heinzmann A, Jerkic SP, Parry R, Cox NJ, Deichmann KA, Ober C. Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci. The Journal of Allergy and Clinical Immunology. 118: 396-402. PMID 16890764 DOI: 10.1016/j.jaci.2006.04.036  0.389
2006 Weiss LA, Kosova G, Delahanty RJ, Jiang L, Cook EH, Ober C, Sutcliffe JS. Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility. European Journal of Human Genetics : Ejhg. 14: 923-31. PMID 16724005 DOI: 10.1038/Sj.Ejhg.5201644  0.756
2006 Weiss LA, Ober C, Cook EH. ITGB3 shows genetic and expression interaction with SLC6A4. Human Genetics. 120: 93-100. PMID 16721604 DOI: 10.1007/s00439-006-0196-z  0.396
2006 Amundadottir LT, Sulem P, Gudmundsson J, Helgason A, Baker A, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Cazier JB, Sainz J, Jakobsdottir M, Kostic J, Magnusdottir DN, Ghosh S, Agnarsson K, ... ... Ober C, et al. A common variant associated with prostate cancer in European and African populations. Nature Genetics. 38: 652-8. PMID 16682969 DOI: 10.1038/Ng1808  0.334
2006 Ober C, Pan L, Phillips N, Parry R, Kurina LM. Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population. Current Allergy and Asthma Reports. 6: 241-6. PMID 16579875 DOI: 10.1007/S11882-006-0041-4  0.454
2006 Ober C, Billstrand C, Kuldanek S, Tan Z. The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells. Human Reproduction (Oxford, England). 21: 1743-8. PMID 16501035 DOI: 10.1093/humrep/del036  0.358
2006 Chan A, Newman DL, Shon AM, Schneider DH, Kuldanek S, Ober C. Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy. Genes and Immunity. 7: 169-78. PMID 16437122 DOI: 10.1038/Sj.Gene.6364287  0.772
2006 Weiss LA, Pan L, Abney M, Ober C. The sex-specific genetic architecture of quantitative traits in humans. Nature Genetics. 38: 218-22. PMID 16429159 DOI: 10.1038/ng1726  0.394
2006 Ober C, Hoffjan S. Asthma genetics 2006: the long and winding road to gene discovery. Genes and Immunity. 7: 95-100. PMID 16395390 DOI: 10.1038/sj.gene.6364284  0.432
2006 Blumenthal MN, Langefeld CD, Barnes KC, Ober C, Meyers DA, King RA, Beaty TH, Beck SR, Bleecker ER, Rich SS. A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity. The Journal of Allergy and Clinical Immunology. 117: 79-85. PMID 16387588 DOI: 10.1016/j.jaci.2005.09.038  0.425
2005 Donfack J, Schneider DH, Tan Z, Kurz T, Dubchak I, Frazer KA, Ober C. Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. Respiratory Research. 6: 145. PMID 16336695 DOI: 10.1186/1465-9921-6-145  0.396
2005 Ober C. HLA-G: an asthma gene on chromosome 6p. Immunology and Allergy Clinics of North America. 25: 669-79. PMID 16257632 DOI: 10.1016/j.iac.2005.08.001  0.437
2005 Tan Z, Shon AM, Ober C. Evidence of balancing selection at the HLA-G promoter region. Human Molecular Genetics. 14: 3619-28. PMID 16236759 DOI: 10.1093/hmg/ddi389  0.387
2005 Ober C, Thompson EE. Rethinking genetic models of asthma: the role of environmental modifiers. Current Opinion in Immunology. 17: 670-8. PMID 16214315 DOI: 10.1016/J.Coi.2005.09.009  0.447
2005 Ober C. Perspectives on the past decade of asthma genetics. The Journal of Allergy and Clinical Immunology. 116: 274-8. PMID 16083779 DOI: 10.1016/j.jaci.2005.04.039  0.436
2005 Shilling RA, Pinto JM, Decker DC, Schneider DH, Bandukwala HS, Schneider JR, Camoretti-Mercado B, Ober C, Sperling AI. Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 175: 2061-5. PMID 16081771 DOI: 10.4049/Jimmunol.175.4.2061  0.687
2005 Zhang J, Schneider D, Ober C, McPeek MS. Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals. Genetic Epidemiology. 29: 128-40. PMID 16049966 DOI: 10.1002/Gepi.20081  0.338
2005 Kurina LM, Weiss LA, Graves SW, Parry R, Williams GH, Abney M, Ober C. Sex differences in the genetic basis of morning serum cortisol levels: genome-wide screen identifies two novel loci specific to women. The Journal of Clinical Endocrinology and Metabolism. 90: 4747-52. PMID 15941864 DOI: 10.1210/Jc.2005-0384  0.338
2005 Hunt JS, Petroff MG, McIntire RH, Ober C. HLA-G and immune tolerance in pregnancy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 681-93. PMID 15857883 DOI: 10.1096/Fj.04-2078Rev  0.347
2005 Weiss LA, Abney M, Parry R, Scanu AM, Cook EH, Ober C. Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample. Human Genetics. 117: 81-7. PMID 15834589 DOI: 10.1007/s00439-004-1250-3  0.352
2005 Weiss LA, Lester LA, Gern JE, Wolf RL, Parry R, Lemanske RF, Solway J, Ober C. Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. American Journal of Respiratory and Critical Care Medicine. 172: 67-73. PMID 15817799 DOI: 10.1164/rccm.200411-1555OC  0.407
2005 Hoffjan S, Nicolae D, Ostrovnaya I, Roberg K, Evans M, Mirel DB, Steiner L, Walker K, Shult P, Gangnon RE, Gern JE, Martinez FD, Lemanske RF, Ober C. Gene-environment interaction effects on the development of immune responses in the 1st year of life. American Journal of Human Genetics. 76: 696-704. PMID 15726497 DOI: 10.1086/429418  0.356
2005 Nicolae D, Cox NJ, Lester LA, Schneider D, Tan Z, Billstrand C, Kuldanek S, Donfack J, Kogut P, Patel NM, Goodenbour J, Howard T, Wolf R, Koppelman GH, White SR, ... ... Ober C, et al. Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. American Journal of Human Genetics. 76: 349-57. PMID 15611928 DOI: 10.1086/427763  0.465
2005 Weiss LA, Abney M, Cook EH, Ober C. Sex-specific genetic architecture of whole blood serotonin levels. American Journal of Human Genetics. 76: 33-41. PMID 15526234 DOI: 10.1086/426697  0.325
2004 Kurz T, Ober C. The role of environmental tobacco smoke in genetic susceptibility to asthma. Current Opinion in Allergy and Clinical Immunology. 4: 335-9. PMID 15349030 DOI: 10.1097/00130832-200410000-00002  0.314
2004 Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH, Abney M. Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. European Journal of Human Genetics : Ejhg. 12: 949-54. PMID 15292919 DOI: 10.1038/Sj.Ejhg.5201239  0.746
2004 Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C. Are common disease susceptibility alleles the same in outbred and founder populations? European Journal of Human Genetics : Ejhg. 12: 584-90. PMID 15100713 DOI: 10.1038/Sj.Ejhg.5201191  0.759
2004 Reed AM, McNallan K, Wettstein P, Vehe R, Ober C. Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? Journal of Immunology (Baltimore, Md. : 1950). 172: 5041-6. PMID 15067086 DOI: 10.4049/jimmunol.172.8.5041  0.318
2004 Blumenthal MN, Ober C, Beaty TH, Bleecker ER, Langefeld CD, King RA, Lester L, Cox N, Barnes K, Togias A, Mathias R, Meyers DA, Oetting W, Rich SS. Genome scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA). Genes and Immunity. 5: 226-31. PMID 15029235 DOI: 10.1038/Sj.Gene.6364063  0.365
2004 Hoffjan S, Ostrovnaja I, Nicolae D, Newman DL, Nicolae R, Gangnon R, Steiner L, Walker K, Reynolds R, Greene D, Mirel D, Gern JE, Lemanske RF, Ober C. Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. The Journal of Allergy and Clinical Immunology. 113: 511-8. PMID 15007355 DOI: 10.1016/J.Jaci.2003.10.044  0.766
2004 Zöllner S, Wen X, Hanchard NA, Herbert MA, Ober C, Pritchard JK. Evidence for extensive transmission distortion in the human genome. American Journal of Human Genetics. 74: 62-72. PMID 14681832 DOI: 10.1086/381131  0.404
2004 Blumenthal MN, Langefeld CD, Beaty TH, Bleecker ER, Ober C, Lester L, Lange E, Barnes KC, Wolf R, King RA, Solway J, Oetting W, Meyers DA, Rich SS. A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma. Human Genetics. 114: 157-64. PMID 14586638 DOI: 10.1007/S00439-003-1030-5  0.358
2003 Hoffjan S, Nicolae D, Ober C. Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respiratory Research. 4: 14. PMID 14748924 DOI: 10.1186/1465-9921-4-14  0.412
2003 Hunt JS, Pace JL, Morales PJ, Ober C. Immunogenicity of the soluble isoforms of HLA-G. Molecular Human Reproduction. 9: 729-35. PMID 14561816 DOI: 10.1093/molehr/gag087  0.309
2003 Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C, McPeek MS. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. American Journal of Human Genetics. 73: 612-26. PMID 12929084 DOI: 10.1086/378208  0.743
2003 Ober C, Aldrich CL, Chervoneva I, Billstrand C, Rahimov F, Gray HL, Hyslop T. Variation in the HLA-G promoter region influences miscarriage rates. American Journal of Human Genetics. 72: 1425-35. PMID 12721954 DOI: 10.1086/375501  0.782
2003 Colilla S, Nicolae D, Pluzhnikov A, Blumenthal MN, Beaty TH, Bleecker ER, Lange EM, Rich SS, Meyers DA, Ober C, Cox NJ. Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. The Journal of Allergy and Clinical Immunology. 111: 840-6. PMID 12704367 DOI: 10.1067/Mai.2003.170  0.397
2003 Donfack J, Kogut P, Forsythe S, Solway J, Ober C. Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. The Journal of Allergy and Clinical Immunology. 111: 527-32. PMID 12642833 DOI: 10.1067/MAI.2003.71  0.403
2003 Newman DL, Abney M, Dytch H, Parry R, McPeek MS, Ober C. Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree. Human Molecular Genetics. 12: 137-44. PMID 12499394 DOI: 10.1093/Hmg/Ddg012  0.747
2003 Blumenthal M, Bleecker E, Beatty T, Ober C, Banks-Schlegel S, Rich S. Genome search for pollen reactivity loci: Genome screen for susceptibility loci contributing to pollen sensitivity in US populations Journal of Allergy and Clinical Immunology. 111: S313. DOI: 10.1016/S0091-6749(03)81139-9  0.323
2002 Hoffjan S, Ober C. Present status on the genetic studies of asthma. Current Opinion in Immunology. 14: 709-17. PMID 12413520 DOI: 10.1016/S0952-7915(02)00393-X  0.405
2002 Bourgain C, Genin E, Ober C, Clerget-Darpoux F. Missing data in haplotype analysis: a study on the MILC method. Annals of Human Genetics. 66: 99-108. PMID 12022148 DOI: 10.1017/S000348000100896X  0.401
2002 Aldrich C, Wambebe C, Odama L, Di Rienzo A, Ober C. Linkage disequilibrium and age estimates of a deletion polymorphism (1597DeltaC) in HLA-G suggest non-neutral evolution. Human Immunology. 63: 405-12. PMID 11975984 DOI: 10.1016/S0198-8859(02)00377-4  0.773
2002 Abney M, Ober C, McPeek MS. Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. American Journal of Human Genetics. 70: 920-34. PMID 11880950 DOI: 10.1086/339705  0.352
2002 Jacob S, McClintock MK, Zelano B, Ober C. Paternally inherited HLA alleles are associated with women's choice of male odor. Nature Genetics. 30: 175-9. PMID 11799397 DOI: 10.1038/Ng830  0.355
2002 Blumenthal MN, Langefeild C, Bleecker ER, Beaty T, Ober C, Banks-Schlegel S, Meyer D, Rich S. Genome screen for susceptibility loci contributing to mite sensitivity in US populations Journal of Allergy and Clinical Immunology. 109: S174-S174. DOI: 10.1016/S0091-6749(02)81651-7  0.321
2001 Ober C. Susceptibility genes in asthma and allergy. Current Allergy and Asthma Reports. 1: 174-9. PMID 11899300 DOI: 10.1007/S11882-001-0085-4  0.461
2001 Meyers DA, Wjst M, Ober C. Description of three data sets: Collaborative Study on the Genetics of Asthma (CSGA), the German Affected-Sib-Pair Study, and the Hutterites of South Dakota. Genetic Epidemiology. 21: S4-8. PMID 11793707 DOI: 10.1002/gepi.2001.21.s1.s4  0.405
2001 Gray HL, Sorensen EL, Hunt JS, Ober C. Three polymorphisms in the 3' UTR of the TRAIL (TNF-related apoptosis-inducing ligand) gene. Genes and Immunity. 2: 469-70. PMID 11781716 DOI: 10.1038/sj.gene.6363806  0.349
2001 Aldrich CL, Stephenson MD, Karrison T, Odem RR, Branch DW, Scott JR, Schreiber JR, Ober C. HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage. Molecular Human Reproduction. 7: 1167-72. PMID 11719594 DOI: 10.1093/Molehr/7.12.1167  0.777
2001 Newman DL, Abney M, McPeek MS, Ober C, Cox NJ. The importance of genealogy in determining genetic associations with complex traits. American Journal of Human Genetics. 69: 1146-8. PMID 11590549 DOI: 10.1086/323659  0.736
2001 Ober C, Abney M, McPeek MS. The genetic dissection of complex traits in a founder population. American Journal of Human Genetics. 69: 1068-79. PMID 11590547 DOI: 10.1086/324025  0.346
2001 Lester LA, Rich SS, Blumenthal MN, Togias A, Murphy S, Malveaux F, Miller ME, Dunston GM, Solway J, Wolf RL, Samet JM, Marsh DG, Meyers DA, Ober C, Bleecker ER, et al. Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma. The Journal of Allergy and Clinical Immunology. 108: 357-62. PMID 11544453 DOI: 10.1067/Mai.2001.117796  0.378
2001 Hackstein H, Hecker M, Kruse S, Bohnert A, Ober C, Deichmann KA, Bein G. A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels. Immunogenetics. 53: 264-9. PMID 11491529 DOI: 10.1007/s002510100324  0.393
2001 Wu X, Di Rienzo A, Ober C. A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor alpha (IL4RA) gene. Genes and Immunity. 2: 128-34. PMID 11426321 DOI: 10.1038/sj.gene.6363746  0.394
2001 Xu J, Meyers DA, Ober C, Blumenthal MN, Mellen B, Barnes KC, King RA, Lester LA, Howard TD, Solway J, Langefeld CD, Beaty TH, Rich SS, Bleecker ER, Cox NJ, et al. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma. American Journal of Human Genetics. 68: 1437-46. PMID 11349227 DOI: 10.1086/320589  0.441
2001 Abney M, McPeek MS, Ober C. Broad and narrow heritabilities of quantitative traits in a founder population. American Journal of Human Genetics. 68: 1302-7. PMID 11309690 DOI: 10.1086/320112  0.325
2001 Mathias RA, Freidhoff LR, Blumenthal MN, Meyers DA, Lester L, King R, Xu JF, Solway J, Barnes KC, Pierce J, Stine OC, Togias A, Oetting W, Marshik PL, Hetmanski JB, ... ... Ober C, et al. Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families. Genetic Epidemiology. 20: 340-55. PMID 11255243 DOI: 10.1002/Gepi.5  0.396
2000 Eklund AC, Ober C. Polymorphic microsatellite markers within the MHC of Peromyscus polionotus. Hereditas. 133: 179-81. PMID 11338432 DOI: 10.1111/J.1601-5223.2000.00179.X  0.351
2000 Hunt JS, Petroff MG, Morales P, Sedlmayr P, Geraghty DE, Ober C. HLA-G in reproduction: studies on the maternal-fetal interface. Human Immunology. 61: 1113-7. PMID 11137215 DOI: 10.1016/S0198-8859(00)00195-6  0.314
2000 Ober C, Tsalenko A, Parry R, Cox NJ. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. American Journal of Human Genetics. 67: 1154-62. PMID 11022011 DOI: 10.1016/S0002-9297(07)62946-2  0.43
2000 Hunt JS, Jadhav L, Chu W, Geraghty DE, Ober C. Soluble HLA-G circulates in maternal blood during pregnancy. American Journal of Obstetrics and Gynecology. 183: 682-8. PMID 10992193 DOI: 10.1067/mob.2000.106762  0.321
2000 Smith KL, Alberts SC, Bayes MK, Bruford MW, Altmann J, Ober C. Cross-species amplification, non-invasive genotyping, and non-Mendelian inheritance of human STRPs in Savannah baboons. American Journal of Primatology. 51: 219-27. PMID 10941438 DOI: 10.1002/1098-2345(200008)51:4<219::Aid-Ajp1>3.0.Co;2-G  0.35
2000 Summerhill E, Leavitt SA, Gidley H, Parry R, Solway J, Ober C. beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites. American Journal of Respiratory and Critical Care Medicine. 162: 599-602. PMID 10934093 DOI: 10.1164/ajrccm.162.2.9910108  0.394
2000 Ober C, Moffatt MF. Contributing factors to the pathobiology. The genetics of asthma. Clinics in Chest Medicine. 21: 245-61. PMID 10907586 DOI: 10.1016/S0272-5231(05)70264-1  0.443
2000 Eklund AC, Belchak MM, Lapidos K, Raha-Chowdhury R, Ober C. Polymorphisms in the HLA-linked olfactory receptor genes in the Hutterites. Human Immunology. 61: 711-7. PMID 10880742 DOI: 10.1016/S0198-8859(00)00132-4  0.406
2000 Donfack J, Tsalenko A, Hoki DM, Parry R, Solway J, Lester LA, Ober C. HLA-DRB1*01 alleles are associated with sensitization to cockroach allergens. The Journal of Allergy and Clinical Immunology. 105: 960-6. PMID 10808177 DOI: 10.1067/mai.2000.106926  0.425
2000 Aldrich C, Verp MS, Walker MA, Ober C. A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation. Journal of Reproductive Immunology. 47: 41-8. PMID 10779589 DOI: 10.1016/S0165-0378(00)00052-8  0.77
2000 Génin E, Ober C, Weitkamp L, Thomson G. A robust test for assortative mating. European Journal of Human Genetics : Ejhg. 8: 119-24. PMID 10757643 DOI: 10.1038/Sj.Ejhg.5200430  0.373
2000 Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, et al. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. American Journal of Human Genetics. 66: 517-26. PMID 10677312 DOI: 10.1086/302781  0.78
1999 Robertson A, Charlesworth D, Ober C. Effect of inbreeding avoidance on Hardy-Weinberg expectations: examples of neutral and selected loci. Genetic Epidemiology. 17: 165-73. PMID 10446464 DOI: 10.1002/(Sici)1098-2272(1999)17:3<165::Aid-Gepi2>3.0.Co;2-L  0.392
1999 Nickel RG, Willadsen SA, Freidhoff LR, Huang SK, Caraballo L, Naidu RP, Levett P, Blumenthal M, Banks-Schlegel S, Bleecker E, Beaty T, Ober C, Barnes KC. Determination of Duffy genotypes in three populations of African descent using PCR and sequence-specific oligonucleotides. Human Immunology. 60: 738-42. PMID 10439320 DOI: 10.1016/S0198-8859(99)00039-7  0.366
1999 Weitkamp LR, Ober C. Ancestral and recombinant 16-locus HLA haplotypes in the Hutterites. Immunogenetics. 49: 491-7. PMID 10380692 DOI: 10.1007/s002510050525  0.356
1999 Ober C. Studies of HLA, fertility and mate choice in a human isolate. Human Reproduction Update. 5: 103-7. PMID 10336015 DOI: 10.1093/humupd/5.2.103  0.389
1999 Kaufman KA, Bowen JA, Tsai AF, Bluestone JA, Hunt JS, Ober C. The CTLA-4 gene is expressed in placental fibroblasts. Molecular Human Reproduction. 5: 84-7. PMID 10050667 DOI: 10.1093/molehr/5.1.84  0.323
1999 Ober C, Hyslop T, Hauck WW. Inbreeding effects on fertility in humans: evidence for reproductive compensation. American Journal of Human Genetics. 64: 225-31. PMID 9915962 DOI: 10.1086/302198  0.348
1998 Tsai AF, Kaufman KA, Walker MA, Karrison TG, Odem RR, Barnes RB, Scott JR, Schreiber JR, Stephenson MD, Ober C. Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage. Journal of Reproductive Immunology. 40: 147-57. PMID 9881742 DOI: 10.1016/S0165-0378(98)00073-4  0.385
1998 Grimsley C, Mather KA, Ober C. HLA-H: a pseudogene with increased variation due to balancing selection at neighboring loci. Molecular Biology and Evolution. 15: 1581-8. PMID 9866194 DOI: 10.1093/OXFORDJOURNALS.MOLBEV.A025886  0.377
1998 Van Der Ven K, Skrablin S, Ober C, Krebs D. HLA-G polymorphisms: Ethnic differences and implications for potential molecule function American Journal of Reproductive Immunology. 40: 145-157. PMID 9764358 DOI: 10.1111/j.1600-0897.1998.tb00406.x  0.342
1998 Ober C, Cox NJ, Abney M, Di Rienzo A, Lander ES, Changyaleket B, Gidley H, Kurtz B, Lee J, Nance M, Pettersson A, Prescott J, Richardson A, Schlenker E, Summerhill E, et al. Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma. Human Molecular Genetics. 7: 1393-8. PMID 9700192 DOI: 10.1093/Hmg/7.9.1393  0.458
1998 Ober C, Aldrich C, Rosinsky B, Robertson A, Walker MA, Willadsen S, Verp MS, Geraghty DE, Hunt JS. HLA-G1 protein expression is not essential for fetal survival Placenta. 19: 127-132. PMID 9548178 DOI: 10.1016/S0143-4004(98)90000-5  0.766
1998 Ober C, Hyslop T, Elias S, Weitkamp LR, Hauck WW. Human leukocyte antigen matching and fetal loss: Results of a 10 year prospective study Human Reproduction. 13: 33-38. PMID 9512225 DOI: 10.1093/Humrep/13.1.33  0.373
1998 Ober C. Do genetics play a role in the pathogenesis of asthma? Journal of Allergy and Clinical Immunology. 101. PMID 9500742 DOI: 10.1016/S0091-6749(98)70234-9  0.394
1998 Nelson JL, Furst DE, Maloney S, Gooley T, Evans PC, Smith A, Bean MA, Ober C, Bianchi DW. Microchimerism and HLA-compatible relationships of pregnancy in scleroderma The Lancet. 351: 559-562. PMID 9492775 DOI: 10.1016/S0140-6736(97)08357-8  0.312
1998 Weitkamp LR, Ober C. Reply to Gill The American Journal of Human Genetics. 62: 986-987. DOI: 10.1086/301801  0.363
1997 Ober C, Aldrich CL. HLA-G polymorphisms: neutral evolution or novel function? Journal of Reproductive Immunology. 36: 1-21. PMID 9430736 DOI: 10.1016/S0165-0378(97)00062-4  0.767
1997 Ober C, Weitkamp LR, Cox N, Dytch H, Kostyu D, Elias S. HLA and mate choice in humans. American Journal of Human Genetics. 61: 497-504. PMID 9326314 DOI: 10.1086/515511  0.379
1997 Ober C, Van Der Ven K. Immunogenetics of reproduction: An overview Current Topics in Microbiology and Immunology. 222: 1-23. PMID 9257483 DOI: 10.1007/978-3-642-60614-4_1  0.327
1997 Marsh DG, Maestri NE, Freidhoff LR, Barnes KC, Togias A, Ehrlich E, Beaty T, Duffy D, Rosenthal R, Imani F, Dunston G, Furbert-Harris P, Malveaux F, Ober C, Cox NJ, et al. A genome-wide search for asthma susceptibility loci in ethnically diverse populations Nature Genetics. 15: 389-392. PMID 9090385 DOI: 10.1038/Ng0497-389  0.357
1997 Grimsley C, Ober C. Population genetic studies of HLA-E: Evidence for selection Human Immunology. 52: 33-40. PMID 9021407 DOI: 10.1016/S0198-8859(96)00241-8  0.386
1997 Ober C, Aldrich C. HLA-G polymorphisms in human populations Journal of Reproductive Immunology. 34: 17. DOI: 10.1016/S0165-0378(97)90383-1  0.764
1996 Ober C, Rosinsky B, Grimsley C, van der Ven K, Robertson A, Runge A. Population genetic studies of HLA-G: allele frequencies and linkage disequilibrium with HLA-A1. Journal of Reproductive Immunology. 32: 111-23. PMID 9023816 DOI: 10.1016/S0165-0378(96)01000-5  0.396
1996 Blumenthal MN, Banks-Schlegel S, Bleecker ER, Marsh DG, Ober C. Collaborative studies on the genetics of asthma--National Heart, Lung and Blood Institute. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 29-32. PMID 8590337 DOI: 10.1111/j.1365-2222.1995.tb00416.x  0.323
1996 Steck T, van der Ven K, Kwak J, Beer A, Ober C. HLA-DQA1 and HLA-DQB1 haplotypes in aborted fetuses and couples with recurrent spontaneous abortion. Journal of Reproductive Immunology. 29: 95-104. PMID 7500323 DOI: 10.1016/0165-0378(95)00937-G  0.369
1996 Ober C. HLA and reproduction: Lessons from studies in the hutterites Placenta. 17: A9. DOI: 10.1016/S0143-4004(96)90097-1  0.316
1996 Lee Nelson J, Furst D, Smith A, Maloney S, Ober C, Hansen JA, Bean MA. Maternal-fetal HLA compatibility is associated with risk of scleroderma (SSc) Human Immunology. 47: 30. DOI: 10.1016/0198-8859(96)84839-7  0.309
1995 Ober C. Current topic: HLA and reproduction: Lessons from studies in the Hutterites Placenta. 16: 569-577. PMID 8577656 DOI: 10.1016/0143-4004(95)90026-8  0.385
1995 Geppert EF, Lester LA, Ober C. Prioritizing asthma research: the need to investigate childhood asthma. American Journal of Respiratory and Critical Care Medicine. 151: 1294-5. PMID 7735577 DOI: 10.1164/ajrccm.151.5.7735577  0.319
1995 Dawson DV, Ober C, Kostyu DD. Extended HLA profile of an inbred isolate: The Schmiedeleut Hutterites of South Dakota Genetic Epidemiology. 12: 47-62. PMID 7713400 DOI: 10.1002/gepi.1370120106  0.342
1994 Ober C, Steck T, van der Ven K, Billstrand C, Messer L, Kwak J, Beaman K, Beer A. MHC class II compatibility in aborted fetuses and term infants of couples with recurrent spontaneous abortion. Journal of Reproductive Immunology. 25: 195-207. PMID 8207709 DOI: 10.1016/0165-0378(93)90063-N  0.359
1993 Kostyu DD, Dawson DV, Elias S, Ober C. Deficit of HLA homozygotes in a Caucasian isolate Human Immunology. 37: 135-142. PMID 8244776 DOI: 10.1016/0198-8859(93)90178-4  0.367
1993 Streck T, van der Ven K, Beer EA, Ober C. Kompatibilität in HLA-DQA1 und HLA-DQB1 Allelen zwischen Mutter und Fetus ist kein zusätzlicher Risikofaktor bei idiopatischen wiederholten Aborten Archives of Gynecology and Obstetrics. 254: 1298-1300. DOI: 10.1007/BF02266403  0.327
1993 Alberts SC, Ober C. Genetic variability in the major histocompatibility complex: A review of non-pathogen-mediated selective mechanisms American Journal of Physical Anthropology. 92: 71-89. DOI: 10.1002/Ajpa.1330360606  0.375
1992 Dawson D, Bryttan J, Ober C, Elias S, Shulman L, Kostyu D. Analysis of HLA haplotype segregation in the schmiedeleut hutterites of South Dakota Human Immunology. 34: 104. DOI: 10.1016/0198-8859(92)90311-A  0.338
1991 Harrison HH, Ober C, Miller KL, Elias S. High-resolution two-dimensional electrophoretic survey of serum protein genetic types in Schmiedeleut Hutterites. American Journal of Human Biology : the Official Journal of the Human Biology Council. 3: 639-646. PMID 28524281 DOI: 10.1002/ajhb.1310030614  0.348
1991 Witt M, Erickson RP, Ober C, Howatt WF, Farber R. Correlation of phenotypic and genetic heterogeneity in cystic fibrosis: variability in sweat electrolyte levels contributes to heterogeneity and is increased with the XV-2c/KM19 B haplotype. American Journal of Medical Genetics. 39: 137-43. PMID 2063915 DOI: 10.1002/ajmg.1320390205  0.36
1991 Hauck WW, Ober C. Statistical analysis of outcomes from repeated pregnancies: Effects of HLA sharing on fetal loss rates Genetic Epidemiology. 8: 187-197. PMID 1955153 DOI: 10.1002/GEPI.1370080305  0.303
1991 Reed AM, Pachman L, Ober C. Molecular genetic studies of major histocompatibility complex genes in children with Juvenile dermatomyositis: Increased risk associated with HLA-DQA1*0501 Human Immunology. 32: 235-240. PMID 1783570 DOI: 10.1016/0198-8859(91)90085-N  0.423
1989 Ober C, Elias S, O'Brien E, Kostyu DD, Hauck WW, Bombard A. HLA sharing and fertility in Hutterite couples: evidence for prenatal selection against compatible fetuses. American Journal of Reproductive Immunology and Microbiology : Ajrim. 18: 111-5. PMID 3245544 DOI: 10.1111/J.1600-0897.1988.TB00245.X  0.341
1989 Ober C, Xiang KS, Thisted RA, Indovina KA, Wason CJ, Dooley S. Increased risk for gestational diabetes mellitus associated with insulin receptor and insulin-like growth factor II restriction fragment length polymorphisms Genetic Epidemiology. 6: 559-569. PMID 2574127 DOI: 10.1002/GEPI.1370060502  0.351
1987 Radvany RM, Vaisrub N, Ober C, Patel KM, Hecht F. The human sex ratio: increase in first-born males to parents with shared HLA-DR antigens. Tissue Antigens. 29: 34-42. PMID 3590144 DOI: 10.1111/J.1399-0039.1987.TB01547.X  0.32
1987 Ober C, Wason CJ, Andrew K, Dooley S. Restriction fragment length polymorphisms of the insulin gene hypervariable region in gestational onset diabetes mellitus American Journal of Obstetrics and Gynecology. 157: 1364-1368. PMID 2892412 DOI: 10.1016/S0002-9378(87)80225-9  0.311
1987 Ober C. : Genetics of Populations . Philip W. Hedrick. American Anthropologist. 89: 209-209. DOI: 10.1525/aa.1987.89.1.02a00750  0.321
1984 Ober C, Olivier TJ, Sade D. Demographic components of gene frequency change in free-ranging macaques on Cayo Santiago American Journal of Physical Anthropology. 64: 223-231. PMID 6476099 DOI: 10.1002/Ajpa.1330640304  0.304
1981 Olivier TJ, Ober C, Buettner-Janusch J, Sade DS. Genetic differentiation among matrilines in social groups of rhesus monkeys Behavioral Ecology and Sociobiology. 8: 279-285. DOI: 10.1007/BF00299527  0.329
1980 Ober C, Olivier TJ, Buettner-Janusch J. Genetic aspects of migration in a rhesus monkey population Journal of Human Evolution. 9: 197-203. DOI: 10.1016/0047-2484(80)90020-2  0.31
Low-probability matches (unlikely to be authored by this person)
1993 Ober C, Weil S, Steck T, Billstrand C, Levrant S, Barnes R. Increased risk for polycystic ovary syndrome associated with human leukocyte antigen DQA1*0501. American Journal of Obstetrics and Gynecology. 167: 1803-6. PMID 1471701 DOI: 10.1016/0002-9378(92)91778-9  0.299
2015 Bouzigon E, Nadif R, Thompson EE, Concas MP, Kuldanek S, Du G, Brossard M, Lavielle N, Sarnowski C, Vaysse A, Dessen P, van der Valk RJ, Duijts L, Henderson AJ, Jaddoe VW, ... ... Ober C, et al. A common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 45: 797-806. PMID 25431337 DOI: 10.1111/Cea.12461  0.299
1996 Mahowald MB, Levinson D, Cassel C, Lemke A, Ober C, Bowman J, Beau ML, Ravin A, Times M. The new genetics and women. Milbank Quarterly. 74: 239-283. DOI: 10.2307/3350248  0.298
2005 Kurina LM, Weiss LA, Graves SW, Parry R, Williams GH, Abney M, Ober C. 431: Genome-Wide Screen Identifies Two Novel Loci Associated with Morning Serum Cortisol Levels in Women American Journal of Epidemiology. 161. DOI: 10.1093/Aje/161.Supplement_1.S108B  0.298
2015 Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, ... ... Ober C, et al. Stress and Bronchodilator Response in Children with Asthma. American Journal of Respiratory and Critical Care Medicine. 192: 47-56. PMID 25918834 DOI: 10.1164/Rccm.201501-0037Oc  0.298
2015 Sengupta S, Gulukota K, Zhu Y, Ober C, Naughton K, Wentworth-Sheilds W, Ji Y. Ultra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samples. Nucleic Acids Research. PMID 26420835 DOI: 10.1093/nar/gkv953  0.296
2020 Morin A, McKennan CG, Pedersen CT, Stokholm J, Chawes BL, Malby Schoos AM, Naughton KA, Thorsen J, Mortensen MS, Vercelli D, Trivedi U, Sørensen SJ, Bisgaard H, Nicolae DL, Bønnelykke K, ... Ober C, et al. Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age. The Journal of Allergy and Clinical Immunology. PMID 32693091 DOI: 10.1016/J.Jaci.2020.07.005  0.295
2023 Dapas M, Lee YL, Wentworth-Sheilds W, Im HK, Ober C, Schoettler N. Revealing polygenic pleiotropy using genetic risk scores for asthma. Hgg Advances. 4: 100233. PMID 37663543 DOI: 10.1016/j.xhgg.2023.100233  0.294
2012 Ding D, Scott NM, Thompson EE, Chaiworapongsa T, Torres R, Billstrand C, Murray K, Dexheimer PJ, Ismail M, Kay H, Levy S, Romero R, Lindheimer MD, Nicolae DL, Ober C. Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia. Reproductive Sciences (Thousand Oaks, Calif.). 19: 1343-51. PMID 22902742 DOI: 10.1177/1933719112450337  0.293
2009 Murmann AE, Conrad DF, Mashek H, Curtis CA, Nicolae RI, Ober C, Schwartz S. Inverted duplications on acentric markers: mechanism of formation. Human Molecular Genetics. 18: 2241-56. PMID 19336476 DOI: 10.1093/Hmg/Ddp160  0.293
1993 Verp MS, Simpson JL, Ober C. Prenatal diagnosis of genetic disorders. Obstetrics & Gynecology. 12: 172-202. DOI: 10.1007/978-1-4613-9240-8_10  0.292
2017 Conboy E, Vairo F, Waggoner D, Ober C, Das S, Dhamija R, Klee EW, Pichurin P. Pathogenic Variant in ACTB, p.Arg183Trp, Causes Juvenile-Onset Dystonia, Hearing Loss, and Developmental Delay without Midline Malformation. Case Reports in Genetics. 2017: 9184265. PMID 28487785 DOI: 10.1155/2017/9184265  0.291
2022 Schoettler N, Dissanayake E, Craven MW, Yee JS, Eliason J, Schauberger EM, Lemanske RF, Ober C, Gern JE. New Insights Relating Gasdermin B to the Onset of Childhood Asthma. American Journal of Respiratory Cell and Molecular Biology. PMID 35580164 DOI: 10.1165/rcmb.2022-0043PS  0.29
1987 Ober C. : Frequencies of Hemoglobin Variants: Thalassemia, the Glucose-6-Phosphate Dehydrogenase Deficiency, G6PD Variants, and Ovalocytosis in Human Populations . Frank B. Livingstone. American Anthropologist. 89: 208-209. DOI: 10.1525/aa.1987.89.1.02a00740  0.289
2021 Soliai MM, Kato A, Helling BA, Stanhope CT, Norton JE, Naughton KA, Klinger AI, Thompson EE, Clay SM, Kim S, Celedón JC, Gern JE, Jackson DJ, Altman MC, Kern RC, ... ... Ober C, et al. Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus. Genome Medicine. 13: 157. PMID 34629083 DOI: 10.1186/s13073-021-00967-y  0.289
1988 OBER C, SIMPSON JL, WARD M, RADVANY RM, ANDERSEN R, ELIAS S, SABBAGHA R. Prenatal Effects of Maternal-Fetal HLA Compatibility Obstetrical & Gynecological Survey. 43: 354-355. DOI: 10.1097/00006254-198806000-00015  0.288
1993 Ober C, Karrison T, Harlow L, Elias S, Gleicher N. Autoantibodies and pregnancy history in a healthy population. American Journal of Obstetrics and Gynecology. 169: 143-7. PMID 8333442 DOI: 10.1016/0002-9378(93)90150-H  0.288
2004 Bourgain C, Abney M, Schneider D, Ober C, McPeek MS. Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics. 168: 2349-61. PMID 15371359 DOI: 10.1534/Genetics.104.031617  0.287
2004 McPeek MS, Wu X, Ober C. Best linear unbiased allele-frequency estimation in complex pedigrees. Biometrics. 60: 359-67. PMID 15180661 DOI: 10.1111/J.0006-341X.2004.00180.X  0.286
2009 Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. Plos Genetics. 5: e1000658. PMID 19763175 DOI: 10.1371/Journal.Pgen.1000658  0.286
2018 Croteau-Chonka DC, Chen Z, Barnes KC, Barraza-Villarreal A, Celedón JC, Gauderman WJ, Gilliland FD, Krishnan JA, Liu AH, London SJ, Martinez FD, Millstein J, Naureckas ET, Nicolae DL, White SR, ... Ober C, et al. Gene Coexpression Networks in Whole Blood Implicate Multiple Interrelated Molecular Pathways in Obesity in People with Asthma. Obesity (Silver Spring, Md.). PMID 30358166 DOI: 10.1002/Oby.22341  0.285
2018 Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, ... ... Ober C, et al. Assembly of a pan-genome from deep sequencing of 910 humans of African descent. Nature Genetics. PMID 30455414 DOI: 10.1038/S41588-018-0273-Y  0.283
2020 Wiesner DL, Merkhofer RM, Ober C, Kujoth GC, Niu M, Keller NP, Gern JE, Brockman-Schneider RA, Evans MD, Jackson DJ, Warner T, Jarjour NN, Esnault SJ, Feldman MB, Freeman M, et al. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host & Microbe. PMID 32130954 DOI: 10.1016/J.Chom.2020.02.006  0.283
2003 Sullivan AE, Lewis T, Stephenson M, Odem R, Schreiber J, Ober C, Branch DW. Pregnancy outcome in recurrent miscarriage patients with skewed X chromosome inactivation. Obstetrics and Gynecology. 101: 1236-42. PMID 12798530 DOI: 10.1016/S0029-7844(03)00345-4  0.282
2014 Davenport ER, Mizrahi-Man O, Michelini K, Barreiro LB, Ober C, Gilad Y. Seasonal variation in human gut microbiome composition. Plos One. 9: e90731. PMID 24618913 DOI: 10.1371/journal.pone.0090731  0.282
2021 Kim KW, Kim DY, Yoon D, Kim KK, Jang H, Schoettler N, Kim E, Kim MN, Hong JY, Lee JK, Kim S, Ober C, Gee HY, Sohn MH. Genome-wide association study identifies TNFSF15associated with childhood asthma. Allergy. PMID 34022066 DOI: 10.1111/all.14952  0.281
1998 Ober C. HLA and pregnancy: The paradox of the fetal allograft American Journal of Human Genetics. 62: 1-5. PMID 9443885 DOI: 10.1086/301692  0.281
2000 Abney M, McPeek MS, Ober C. Estimation of variance components of quantitative traits in inbred populations. American Journal of Human Genetics. 66: 629-50. PMID 10677322 DOI: 10.1086/302759  0.28
2021 Hallmark B, Wegienka G, Havstad S, Billheimer D, Ownby D, Mendonca EA, Gress L, Stern DA, Myers JB, Khurana Hershey GK, Hoepner L, Miller RL, Lemanske RF, Jackson DJ, Gold DR, ... ... Ober C, et al. Chromosome 17q12-21 Variants are Associated with Multiple Wheezing Phenotypes in Childhood. American Journal of Respiratory and Critical Care Medicine. PMID 33535024 DOI: 10.1164/rccm.202003-0820OC  0.28
2020 Wu FL, Strand AI, Cox LA, Ober C, Wall JD, Moorjani P, Przeworski M. A comparison of humans and baboons suggests germline mutation rates do not track cell divisions. Plos Biology. 18: e3000838. PMID 32804933 DOI: 10.1371/Journal.Pbio.3000838  0.278
1989 OBER C, ELIAS S, OʼBRIEN E, KOSTYU DD, HAUCK WW, BOMBARD A. HLA Sharing Evidence and Fertility in Hutterite Couples Obstetrical & Gynecological Survey. 44: 625-626. DOI: 10.1097/00006254-198908000-00019  0.278
2009 Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, et al. From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proceedings of the National Academy of Sciences of the United States of America. 106: 226-31. PMID 19114657 DOI: 10.1073/Pnas.0808358106  0.278
2019 Basnet S, Bochkov YA, Brockman-Schneider RA, Kuipers I, Aesif SW, Jackson DJ, Lemanske RF, Ober C, Palmenberg AC, Gern JE. CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections. American Journal of Respiratory Cell and Molecular Biology. PMID 30916989 DOI: 10.1165/Rcmb.2018-0220Oc  0.277
1996 Van Der Ven K, Messer L, Van Der Ven H, Jeyendran RS, Ober C. Cystic fibrosis mutation screening in healthy men with reduced sperm quality Human Reproduction. 11: 513-517. PMID 8671256 DOI: 10.1093/HUMREP/11.3.513  0.277
1978 Ober C, Olivier TJ, Buettner-Janusch J. Carbonic anhydrase heterozygosity and F(ST) distributions in Kenyan baboon troops American Journal of Physical Anthropology. 48: 95-100. PMID 414627 DOI: 10.1002/Ajpa.1330480114  0.276
1998 Camoretti-Mercado B, Forsythe SM, LeBeau MM, Espinosa R, Vieira JE, Halayko AJ, Willadsen S, Kurtz B, Ober C, Evans GA, Thweatt R, Shapiro S, Niu Q, Qin Y, Padrid PA, et al. Expression and cytogenetic localization of the human SM22 gene (TAGLN). Genomics. 49: 452-7. PMID 9615232 DOI: 10.1006/Geno.1998.5267  0.275
2021 Sobreira DR, Joslin AC, Zhang Q, Williamson I, Hansen GT, Farris KM, Sakabe NJ, Sinnott-Armstrong N, Bozek G, Jensen-Cody SO, Flippo KH, Ober C, Bickmore WA, Potthoff M, Chen M, et al. Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of and . Science (New York, N.Y.). 372: 1085-1091. PMID 34083488 DOI: 10.1126/science.abf1008  0.274
1999 Ober C, Karrison T, Odem RR, Barnes RB, Branch DW, Stephenson MD, Baron B, Walker MA, Scott JR, Schreiber JR. Mononuclear-cell immunisation in prevention of recurrent miscarriages: a randomised trial. Lancet. 354: 365-9. PMID 10437864 DOI: 10.1016/S0140-6736(98)12055-X  0.273
2024 Djeddi S, Fernandez-Salinas D, Huang GX, Aguiar VRC, Mohanty C, Kendziorski C, Gazal S, Boyce J, Ober C, Gern J, Barrett N, Gutierrez-Arcelus M. Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic susceptibility to childhood-onset asthma. Medrxiv : the Preprint Server For Health Sciences. PMID 38370648 DOI: 10.1101/2024.02.02.24302068  0.271
2018 Knowles DA, Burrows CK, Blischak JD, Patterson KM, Serie DJ, Norton N, Ober C, Pritchard JK, Gilad Y. Author response: Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes Elife. DOI: 10.7554/Elife.33480.050  0.269
2004 Dobyns WB, Filauro A, Tomson BN, Chan AS, Ho AW, Ting NT, Oosterwijk JC, Ober C. Inheritance of most X-linked traits is not dominant or recessive, just X-linked. American Journal of Medical Genetics. Part A. 129: 136-43. PMID 15316978 DOI: 10.1002/Ajmg.A.30123  0.265
2020 Ahluwalia TS, Eliasen AU, Sevelsted A, Pedersen CT, Stokholm J, Chawes B, Bork-Jensen J, Grarup N, Pedersen O, Hansen T, Linneberg A, Sharma A, Weiss ST, Evans MD, Jackson DJ, ... ... Ober C, et al. FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nature Communications. 11: 6398. PMID 33328473 DOI: 10.1038/s41467-020-19814-6  0.264
2013 Abe K, Ohno Y, Sassa T, Taguchi R, Çalışkan M, Ober C, Kihara A. Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile. The Journal of Biological Chemistry. 288: 36741-9. PMID 24220030 DOI: 10.1074/Jbc.M113.493221  0.264
1986 Freinkel N, Metzger BE, Phelps RL, Simpson JL, Martin AO, Radvany R, Ober C, Dooley SL, Depp RO, Belton A. Gestational diabetes mellitus: A syndrome with phenotypic and genotypic heterogeneity Hormone and Metabolic Research. 18: 427-430. PMID 3527923 DOI: 10.1055/S-2007-1012338  0.264
2015 Chapman KM, Medrano GA, Jaichander P, Chaudhary J, Waits AE, Nobrega MA, Hotaling JM, Ober C, Hamra FK. Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells. Cell Reports. 10: 1828-35. PMID 25772367 DOI: 10.1016/J.Celrep.2015.02.040  0.264
1993 Margulis SW, Altmann J, Ober C. Sex-biased lactational duration in a human population and its reproductive costs. Behavioral Ecology and Sociobiology. 32: 41-5. PMID 12286204 DOI: 10.1007/Bf00172221  0.263
2015 Kim KW, Myers RA, Lee JH, Igartua C, Lee KE, Kim YH, Kim EJ, Yoon D, Lee JS, Hirota T, Tamari M, Takahashi A, Kubo M, Choi JM, Kim KE, ... ... Ober C, et al. Genome-wide association study of recalcitrant atopic dermatitis in Korean children. The Journal of Allergy and Clinical Immunology. PMID 25935106 DOI: 10.1016/J.Jaci.2015.03.030  0.263
2014 Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, ... ... Ober C, et al. Genome-wide association study of lung function phenotypes in a founder population. The Journal of Allergy and Clinical Immunology. 133: 248-55.e1-10. PMID 23932459 DOI: 10.1016/J.Jaci.2013.06.018  0.263
1985 Ober C, Leigh Simpson J, Radvany R. INCREASED MALE-TO-FEMALE SEX RATIO AMONG HLA-DR COMPATIBLE PREGNANCIES The Lancet. 325: 761. PMID 2858031 DOI: 10.1016/S0140-6736(85)91307-8  0.262
2021 Daya M, Cox C, Acevedo N, Boorgula MP, Campbell M, Chavan S, Cho MH, David GL, Kachroo P, Lasky-Su J, Li X, McHugh CP, Qiao D, Rafaels N, Beck LA, ... ... Ober C, et al. Multi-ethnic genome-wide and HLA association study of total serum IgE. The Journal of Allergy and Clinical Immunology. PMID 34536413 DOI: 10.1016/j.jaci.2021.09.011  0.262
2021 Altman MC, Flynn K, Rosasco MG, Dapas M, Kattan M, Lovinsky-Desir S, O'Connor GT, Gill MA, Gruchalla RS, Liu AH, Pongracic JA, Khurana Hershey GK, Zoratti EM, Teach SJ, Rastrogi D, ... ... Ober C, et al. Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children. The Journal of Allergy and Clinical Immunology. PMID 34019912 DOI: 10.1016/j.jaci.2021.04.035  0.262
1993 Verp MS, Sibul M, Billstrand C, Bellen G, Hsu M, Ober C. Maternal-fetal histocompatibility in intrauterine growth retarded and normal weight babies. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 29: 195-8. PMID 8397808 DOI: 10.1111/j.1600-0897.1993.tb00586.x  0.259
2004 Gern JE, Reardon CL, Hoffjan S, Nicolae D, Li Z, Roberg KA, Neaville WA, Carlson-Dakes K, Adler K, Hamilton R, Anderson E, Gilbertson-White S, Tisler C, Dasilva D, Anklam K, ... ... Ober C, et al. Effects of dog ownership and genotype on immune development and atopy in infancy. The Journal of Allergy and Clinical Immunology. 113: 307-14. PMID 14767447 DOI: 10.1016/J.Jaci.2003.11.017  0.258
2023 Dapas M, Thompson EE, Wentworth-Sheilds W, Clay S, Visness CM, Calatroni A, Sordillo JE, Gold DR, Wood RA, Makhija M, Khurana Hershey GK, Sherenian MG, Gruchalla RS, Gill MA, Liu AH, ... ... Ober C, et al. Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. Plos Genetics. 19: e1010594. PMID 36638096 DOI: 10.1371/journal.pgen.1010594  0.258
2006 Thompson E, Murray C, Burkart M, Nicolae D, Gilad Y, Ober C. Haplotype Structure and Natural Selection in an Olfactory Receptor (OR) Gene on Chromosome 6p Associated with Asthma Susceptibility Journal of Allergy and Clinical Immunology. 117: S149. DOI: 10.1016/J.Jaci.2005.12.595  0.258
2018 Sun S, Zhu J, Mozaffari S, Ober C, Chen M, Zhou X. Heritability Estimation and Differential Analysis with Generalized Linear Mixed Models in Genomic Sequencing Studies. Bioinformatics (Oxford, England). PMID 30020412 DOI: 10.1093/Bioinformatics/Bty644  0.257
2019 Abdelfatah N, Chen R, Duff HJ, Seifer CM, Buffo I, Huculak C, Clarke S, Clegg R, Jassal DS, Gordon PMK, Ober C, Frosk P, Gerull B. Characterization of a Unique Form of Arrhythmic Cardiomyopathy Caused by Recessive Mutation in LEMD2. Jacc. Basic to Translational Science. 4: 204-221. PMID 31061923 DOI: 10.1016/j.jacbts.2018.12.001  0.256
1998 Karrison TG, Ober C. Recurrent miscarriage (REMIS) Study: How should data from women who do not become pregnant be handled? Controlled Clinical Trials. 19: 430-439. PMID 9741864 DOI: 10.1016/S0197-2456(98)00019-1  0.254
2005 McClintock MK, Bullivant S, Jacob S, Spencer N, Zelano B, Ober C. Human body scents: conscious perceptions and biological effects. Chemical Senses. 30: i135-7. PMID 15738077 DOI: 10.1093/Chemse/Bjh151  0.252
2011 Alvarado Arnez LE, Venegas EN, Ober C, Thompson EE. Sequence variation in the IL4 gene and resistance to Trypanosoma cruzi infection in Bolivians. The Journal of Allergy and Clinical Immunology. 127: 279-82, 282.e1-3. PMID 21211660 DOI: 10.1016/J.Jaci.2010.10.026  0.251
1992 Kostyu D, Dawson D, Bryttan J, Elias S, Dungan J, Ober C. Deficit of HLA homozygotes is class I and class II dependent Human Immunology. 34: 105. DOI: 10.1016/0198-8859(92)90312-B  0.25
2021 Joslin AC, Sobreira DR, Hansen GT, Sakabe NJ, Aneas I, Montefiori LE, Farris KM, Gu J, Lehman DM, Ober C, He X, Nóbrega MA. A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Nature Communications. 12: 5253. PMID 34489471 DOI: 10.1038/s41467-021-25614-3  0.249
1992 Verp MS, Harrison HH, Ober C, Oliveri D, Amarose AP, Lindgren V, Talerman A. Chimerism as the etiology of a 46,XX/46,XY fertile true hermaphrodite. Fertility and Sterility. 57: 346-9. PMID 1735486 DOI: 10.1016/S0015-0282(16)54843-2  0.248
2016 Hilkert SM, Parness-Yossifon R, Ober C, Mets MB. Ocular biometry and determinants of refractive error in the Hutterites, a founder population of European ancestry Journal of American Association For Pediatric Ophthalmology and Strabismus. 20: e33. DOI: 10.1016/j.jaapos.2016.07.126  0.246
1989 Simpson JL, Meyers CM, Martin AO, Elias S, Ober C. Translocations are infrequent among couples having repeated spontaneous abortions but no other abnormal pregnancies**Supported by the National Institutes of Health grants HD 19866, HD 21414, and HD 82904, by The March of Dimes, and by The United States Agency for International Development (Institute for International Studies in Natural Family Planning). Fertility and Sterility. 51: 811-814. DOI: 10.1016/S0015-0282(16)60671-4  0.246
2008 Joseph JW, Neidich AB, Ober C, Ross LF. Empirical data about women's attitudes toward a biobank focused on pregnancy outcomes. American Journal of Medical Genetics. Part A. 146: 305-11. PMID 18203186 DOI: 10.1002/ajmg.a.32146  0.244
1986 Simpson JL, Baum LD, Marder R, Elias S, Ober C, Martin AO. Maternal serum alpha-fetoprotein screening: low and high values for detection of genetic abnormalities. American Journal of Obstetrics and Gynecology. 155: 593-7. PMID 2428249 DOI: 10.1016/0002-9378(86)90285-1  0.242
2008 Neidich AB, Joseph JW, Ober C, Ross LF. Empirical data about women's attitudes towards a hypothetical pediatric biobank. American Journal of Medical Genetics. Part A. 146: 297-304. PMID 18205141 DOI: 10.1002/ajmg.a.32145  0.242
1997 Karrison T, Ober C. P14 Recurrent miscarriage study: How should data from women who do not become pregnant be handled? Controlled Clinical Trials. 18: S118-S119. DOI: 10.1016/S0197-2456(97)91109-0  0.24
2022 Magnaye KM, Clay SM, Nicodemus-Johnson J, Naughton KA, Huffman J, Altman MC, Jackson DJ, Gern JE, Hogarth DK, Naureckas ET, White SR, Ober C. DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma. Proceedings of the National Academy of Sciences of the United States of America. 119: e2116467119. PMID 35666868 DOI: 10.1073/pnas.2116467119  0.239
2014 Breton CV, Siegmund KD, Joubert BR, Wang X, Qui W, Carey V, Nystad W, Håberg SE, Ober C, Nicolae D, Barnes KC, Martinez F, Liu A, Lemanske R, Strunk R, et al. Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation. Plos One. 9: e99716. PMID 24964093 DOI: 10.1371/Journal.Pone.0099716  0.238
2020 Helling BA, Sobreira DR, Hansen GT, Sakabe NJ, Luo K, Billstrand C, Laxman B, Nicolae RI, Nicolae DL, Bochkov YA, Gern JE, Nobrega MA, White SR, Ober C. Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma. Communications Biology. 3: 678. PMID 33188283 DOI: 10.1038/s42003-020-01411-4  0.235
1997 Fisfalen ME, Soltani K, Kaplan E, Palmer EM, van Seventer GA, Straus FH, Diaz M, Ober C, DeGroot LJ. Evaluating the role of Th0 and Th1 clones in autoimmune thyroid disease by use of Hu-SCID chimeras. Clinical Immunology and Immunopathology. 85: 253-64. PMID 9400625 DOI: 10.1006/Clin.1997.4431  0.232
2019 Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, ... ... Ober C, et al. Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent. Nature Genetics. PMID 30647471 DOI: 10.1038/S41588-018-0335-1  0.231
1997 Fisfalen ME, Palmer EM, Van Seventer GA, Soltani K, Sawai Y, Kaplan E, Hidaka Y, Ober C, DeGroot LJ. Thyrotropin-receptor and thyroid peroxidase-specific T cell clones and their cytokine profile in autoimmune thyroid disease. The Journal of Clinical Endocrinology and Metabolism. 82: 3655-63. PMID 9360522 DOI: 10.1210/Jcem.82.11.4336  0.23
2018 Daya M, Shetty A, Rafaels NM, Ortega VE, Bleecker ER, Meyers DA, Ober C, Williams LK, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC. Admixture Mapping of Total Serum IgE in African American subjects from CAAPA Journal of Allergy and Clinical Immunology. 141: AB116. DOI: 10.1016/J.Jaci.2017.12.370  0.229
2017 Montefiori L, Hernandez L, Zhang Z, Gilad Y, Ober C, Crawford G, Nobrega M, Jo Sakabe N. Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9. Scientific Reports. 7: 2451. PMID 28550296 DOI: 10.1038/S41598-017-02547-W  0.227
2020 McKennan C, Naughton K, Stanhope C, Kattan M, O'Connor GT, Sandel MT, Visness CM, Wood RA, Bacharier LB, Beigelman A, Lovinsky-Desir S, Togias A, Gern JE, Nicolae D, Ober C. Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels. Epigenetics. 1-15. PMID 32997571 DOI: 10.1080/15592294.2020.1817290  0.225
1985 Martin AO, Simpson JL, Ober C, Freinkel N. Frequency of diabetes mellitus in mothers of probands with gestational diabetes: Possible maternal influence on the predisposition to gestational diabetes American Journal of Obstetrics and Gynecology. 151: 471-475. PMID 3976747 DOI: 10.1016/0002-9378(85)90272-8  0.224
2018 Workman LJ, Retterer M, Wilson JM, Holbreich M, von Mutius E, Stein MM, Ober C, Platts-Mills TA. Milk-specific IgE and IgG4 responses are lower in Amish than Hutterite children Journal of Allergy and Clinical Immunology. 141: AB231. DOI: 10.1016/j.jaci.2017.12.730  0.223
2014 Holbreich M, Stein M, Anderson R, Metwali N, Thorne PS, Vercelli D, Von Mutius E, Ober C. Allergic Sensitization and Enviromental Exposures In Amish and Hutterite Children Journal of Allergy and Clinical Immunology. 133: AB13. DOI: 10.1016/J.Jaci.2013.12.071  0.218
2022 Washington C, Dapas M, Biddanda A, Magnaye KM, Aneas I, Helling BA, Szczesny B, Boorgula MP, Taub MA, Kenny E, Mathias RA, Barnes KC, Khurana Hershey GK, Kercsmar CM, Gereige JD, ... ... Ober C, et al. African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Medicine. 14: 112. PMID 36175932 DOI: 10.1186/s13073-022-01114-x  0.214
2021 Stein MM, Conery M, Magnaye KM, Clay SM, Billstrand C, Nicolae R, Naughton K, Ober C, Thompson EE. Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes. Scientific Reports. 11: 1107. PMID 33441806 DOI: 10.1038/s41598-020-80145-z  0.211
2021 Magnaye KM, Naughton KA, Huffman J, Hogarth DK, Naureckas ET, White SR, Ober C. A-to-I editing of miR-200b-3p in airway cells is associated with moderate-to-severe asthma. The European Respiratory Journal. PMID 33446603 DOI: 10.1183/13993003.03862-2020  0.211
2010 Loisel DA, Alberts SC, Ober C. Functional significance of MHC variation in mate choice, reproductive outcome, and disease risk Evolution in Health and Disease. DOI: 10.1093/acprof:oso/9780199207466.003.0008  0.208
2002 McClintock MK, Schumm P, Jacob S, Zelano B, Ober C. Reply to “The MHC and body odors: arbitrary effects caused by shifts of mean pleasantness” Nature Genetics. 31: 237-238. DOI: 10.1038/0702-237B  0.207
2006 Tan Z, Fan J, Shon A, Schwartz M, Camoretti-Mercado B, Ober C. A Polymorphism in the HLA-G 3′-UTR Influences Targeting of mir-148 and is Associated with Asthma Journal of Allergy and Clinical Immunology. 117: S141. DOI: 10.1016/J.JACI.2005.12.563  0.206
2020 McKennan C, Ober C, Nicolae D. Estimation and inference in metabolomics with nonrandom missing data and latent factors The Annals of Applied Statistics. 14: 789-808. DOI: 10.1214/20-Aoas1328  0.202
2023 Sevelsted A, Pedersen CT, Gürdeniz G, Rasmussen MA, Schullehner J, Sdougkou K, Martin JW, Lasky-Su J, Morin A, Ober C, Schoos AM, Stokholm J, Bønnelykke K, Chawes B, Bisgaard H. Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort. Ebiomedicine. 94: 104699. PMID 37429082 DOI: 10.1016/j.ebiom.2023.104699  0.201
2024 Bunyavanich S, Becker PM, Altman MC, Lasky-Su J, Ober C, Zengler K, Berdyshev E, Bonneau R, Chatila T, Chatterjee N, Chung KF, Cutcliffe C, Davidson W, Dong G, Fang G, et al. Analytical Challenges in Omics Research on Asthma and Allergy: A National Institute of Allergy and Infectious Diseases Workshop. The Journal of Allergy and Clinical Immunology. PMID 38295882 DOI: 10.1016/j.jaci.2024.01.014  0.201
2019 Mozaffari SV, DeCara JM, Shah SJ, Sidore C, Fiorillo E, Cucca F, Lang RM, Nicolae DL, Ober C. Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree. Communications Biology. 2: 28. PMID 31924898 DOI: 10.1038/s42003-018-0267-4  0.2
2019 Mozaffari SV, DeCara JM, Shah SJ, Sidore C, Fiorillo E, Cucca F, Lang RM, Nicolae DL, Ober C. Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree. Communications Biology. 2: 28. PMID 30675526 DOI: 10.1038/s42003-018-0267-4  0.2
2020 Sakabe NJ, Aneas I, Knoblauch N, Sobreira DR, Clark N, Paz C, Horth C, Ziffra R, Kaur H, Liu X, Anderson R, Morrison J, Cheung VC, Grotegut C, Reddy TE, ... ... Ober C, et al. Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. Science Advances. 6. PMID 33268355 DOI: 10.1126/sciadv.abc8696  0.199
2011 Kurina LM, Knutson KL, Hawkley LC, Cacioppo JT, Lauderdale DS, Ober C. Loneliness is associated with sleep fragmentation in a communal society. Sleep. 34: 1519-26. PMID 22043123 DOI: 10.5665/Sleep.1390  0.197
2023 Melén E, Lambrecht BN, Lloyd CM, Rothenberg ME, Kabashima K, Luciani F, Coquet JM, Ober C, Nawijn MC, Platts-Mills T, von Mutius E. A conversation on allergy: recognizing the past and looking to the future. Immunology and Cell Biology. 101: 936-946. PMID 37688499 DOI: 10.1111/imcb.12688  0.195
1986 Ober C, Simpson JL. Diabetes Mellitus: Preventing Anomalies Through Maternal Metabolic Intervention Anesthesiology. 29: 558-568. DOI: 10.1097/00000542-198609000-00012  0.194
2022 Jackman JK, Stockwell A, Choy DD, Xie MM, Lu P, Jia G, Li H, Abbas AR, Bronson PG, Lin WY, Chiu CPC, Maun HR, Roose-Girma M, Tam L, Zhang J, ... ... Ober C, et al. Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma. The Journal of Allergy and Clinical Immunology. PMID 35487308 DOI: 10.1016/j.jaci.2022.03.033  0.194
2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, ... ... Ober C, et al. Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nature Genetics. PMID 30116036 DOI: 10.1038/S41588-018-0197-6  0.193
1988 LaBarbera AR, Miller MM, Ober C, Rebar RW. Autoimmune etiology in premature ovarian failure American Journal of Reproductive Immunology and Microbiology. 16: 115-122. PMID 3289410 DOI: 10.1111/J.1600-0897.1988.TB00180.X  0.191
2017 Lamont RE, Beaulieu CL, Bernier FP, Sparkes R, Innes AM, Jackel-Cram C, Ober C, Parboosingh JS, Lemire EG. Response to correspondence of NDUFS4-related Leigh syndrome in Hutterites. American Journal of Medical Genetics. Part A. PMID 28371264 DOI: 10.1002/ajmg.a.38227  0.189
2007 Shah SJ, Ober C, Lang RM. Two-Dimensional Echocardiography Is Superior to M-mode for the Determination of Left Ventricular Mass: Evidence from a Heritability Study Journal of Cardiac Failure. 13: S155. DOI: 10.1016/j.cardfail.2007.06.650  0.186
1989 Ober C. Major histocompatibility (MHC) genes in reproduction: Results of prospective, population-based studies in U.S. hutterites Journal of Reproductive Immunology. 15: 22. DOI: 10.1016/0165-0378(89)90080-6  0.183
2022 Eliasen AU, Pedersen CET, Rasmussen MA, Wang N, Soverini M, Fritz A, Stokholm J, Chawes BL, Morin A, Bork-Jensen J, Grarup N, Pedersen O, Hansen T, Linneberg A, Mortensen PB, ... ... Ober C, et al. Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. The Journal of Allergy and Clinical Immunology. PMID 35381269 DOI: 10.1016/j.jaci.2022.03.019  0.18
2023 Morin A, Thompson EE, Helling BA, Shorey-Kendrick LE, Faber P, Gebretsadik T, Bacharier LB, Kattan M, O'Connor GT, Rivera-Spoljaric K, Wood RA, Barnes KC, Mathias RA, Altman MC, Hansen K, ... ... Ober C, et al. A Functional Genomics Pipeline to Identify High-Value Asthma and Allergy CpGs in the Human Methylome. The Journal of Allergy and Clinical Immunology. PMID 36754293 DOI: 10.1016/j.jaci.2022.12.828  0.179
2023 Dos Santos MM, Pivniouk V, Rankl B, Walker A, Pagani G, Hertkorn N, Schmitt-Kopplin P, Müller C, Bracher F, Merl-Pham J, Hauck SM, Schloter M, Michael AN, Anderson D, Honeker L, ... ... Ober C, et al. Asthma-protective agents in dust from traditional farm environments. The Journal of Allergy and Clinical Immunology. PMID 37271318 DOI: 10.1016/j.jaci.2023.05.013  0.178
1991 Verp MS, Ober C, Oliveri DR, Israel J. Delayed diagnosis of pseudohermaphroditism on stored blood spot. Lancet (London, England). 337: 1037. PMID 1673185 DOI: 10.1016/0140-6736(91)92693-V  0.175
2021 Turi KN, McKennan C, Gebretsadik T, Snyder B, Seroogy CM, Lemanske RF, Zoratti E, Havstad S, Ober C, Lynch S, McCauley K, Yu C, Jackson DJ, Gern JE, Hartert TV, et al. Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma. The Journal of Allergy and Clinical Immunology. PMID 33434532 DOI: 10.1016/j.jaci.2020.12.639  0.173
1988 Kostyu D, Ober C, Dawson D, Ghanayem M, Elias S, Martin A. HLA and fertility in the schmiedenleut hutterites Human Immunology. 23: 114-115. DOI: 10.1016/0198-8859(88)90185-1  0.164
2022 Chung J, Das A, Sun X, Sobreira DR, Leung YY, Igartua C, Mozaffari S, Chou YF, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle BW, Martin ER, ... ... Ober C, et al. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35770850 DOI: 10.1002/alz.12719  0.162
2006 Bufford J, Li Z, Reardon C, Roberg K, Tisler C, Anderson E, DaSilva D, Ostrovnaja I, Hoffjan S, Nicolae D, Gangnon R, Ober C, Lemanske R, Gern J. Time-dependent Effects of Dog Exposure and Genotype at Immune-Related Genes on Wheezing and Atopy in Early Childhood Journal of Allergy and Clinical Immunology. 117: S186. DOI: 10.1016/J.Jaci.2005.12.738  0.157
2016 Gozdz J, Ober C, Vercelli D. Innate Immunity and Asthma Risk. The New England Journal of Medicine. 375: 1898-1899. PMID 27959651 DOI: 10.1056/NEJMc1611699  0.155
2015 Loucks CM, Parboosingh JS, Shaheen R, Bernier FP, Mcleod DR, Seidahmed MZ, Puffenberger EG, Ober C, Hegele RA, Boycott KM, Alkuraya FS, Innes AM. Matching Two Independent Cohorts Validates DPH1 as a Gene Responsible for Autosomal Recessive Intellectual Disability with Short Stature, Craniofacial, and Ectodermal Anomalies Human Mutation. DOI: 10.1002/humu.22843  0.149
2024 Hamilton RG, Holbreich M, Bronzert C, Anderson RL, Schoettler N, Ober C. Screening asthmatics for atopic status using the ALergy EXplorer (ALEX) macroarray. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 1-8. PMID 38415683 DOI: 10.1080/02770903.2024.2324839  0.142
2021 Soliai M, Sundaresan AS, Morin A, Hirsch AG, Stanhope C, Kuiper J, Schwartz BS, Ober C, Pinto JM. Two-stage genome-wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk. International Forum of Allergy & Rhinology. PMID 33393196 DOI: 10.1002/alr.22731  0.139
2022 Tingskov Pedersen CE, Eliasen AU, Ketzel M, Brandt J, Loft S, Frohn LM, Khan J, Brix S, Rasmussen MA, Stokholm J, Morin A, Ober C, Bisgaard H, Pedersen M, Bønnelykke K. Prenatal exposure to ambient air pollution is associated with early life immune perturbations. The Journal of Allergy and Clinical Immunology. PMID 36075322 DOI: 10.1016/j.jaci.2022.08.020  0.132
2023 Dissanayake E, Brockman-Schneider RA, Stubbendieck RM, Helling BA, Zhang Z, Bochkov YA, Kirkham C, Murphy TF, Ober C, Currie CR, Gern JE. Rhinovirus increases adhesion to the respiratory epithelium. Frontiers in Cellular and Infection Microbiology. 12: 1060748. PMID 36733852 DOI: 10.3389/fcimb.2022.1060748  0.129
2022 Snyder BM, Gebretsadik T, Turi KN, McKennan C, Havstad S, Jackson DJ, Ober C, Lynch S, McCauley K, Seroogy CM, Zoratti EM, Khurana Hershey GK, Berdnikovs S, Cunningham G, Summar ML, et al. Association of citrulline concentration at birth with lower respiratory tract infection in infancy: Findings from a multi-site birth cohort study. Frontiers in Pediatrics. 10: 979777. PMID 36324820 DOI: 10.3389/fped.2022.979777  0.126
2023 Bisgaard H, Mikkelsen M, Rasmussen MA, Sevelsted A, Schoos AM, Brustad N, Eliasen AU, Thorsen J, Chawes B, Gürdeniz G, Morin A, Stark K, Stokholm J, Ober C, Pedersen CET, et al. Atopic and non-atopic effects of fish oil supplementation during pregnancy. Thorax. 78: 1168-1174. PMID 37696621 DOI: 10.1136/thorax-2022-219725  0.122
2023 Liu X, Aneas I, Sakabe N, Anderson RL, Billstrand C, Paz C, Kaur H, Furner B, Choi S, Prichina AY, Enninga EAL, Dong H, Murtha A, Crawford GE, Kessler JA, ... ... Ober C, et al. Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1 non-immune cells in human spontaneous preterm labor. Scientific Reports. 13: 7903. PMID 37193763 DOI: 10.1038/s41598-023-35051-5  0.108
2023 Soliai MM, Kato A, Naughton KA, Norton JE, Klinger AI, Kern RC, Tan BK, Nicolae DL, Schleimer RP, Ober C, Pinto JM. Epigenetic responses to rhinovirus exposure in airway epithelial cells are correlated with key transcriptional pathways in chronic rhinosinusitis. Allergy. PMID 37571876 DOI: 10.1111/all.15837  0.096
2011 Gamble KC, Moyse JA, Lovstad JN, Ober CB, Thompson EE. Blood groups in the Species Survival Plan®, European endangered species program, and managed in situ populations of bonobo (Pan paniscus), common chimpanzee (Pan troglodytes), gorilla (Gorilla ssp.), and orangutan (Pongo pygmaeus ssp.). Zoo Biology. 30: 427-44. PMID 20853409 DOI: 10.1002/Zoo.20348  0.096
2002 BOURGAIN C, GENIN E, OBER C, CLERGET-DARPOUX F. Missing data in haplotype analysis: a study on the MILC method Annals of Human Genetics. 66: 99-108. DOI: 10.1046/j.1469-1809.2002.6610099.x  0.096
2021 Cheung VC, Peng CY, Marinić M, Sakabe NJ, Aneas I, Lynch VJ, Ober C, Nobrega MA, Kessler JA. Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua. Cell Reports. 35: 109138. PMID 34010658 DOI: 10.1016/j.celrep.2021.109138  0.09
2021 Bai T, Peng CY, Aneas I, Sakabe N, Requena DF, Billstrand C, Nobrega M, Ober C, Parast M, Kessler JA. Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts. Stem Cell Research. 56: 102507. PMID 34454392 DOI: 10.1016/j.scr.2021.102507  0.086
1988 SIMPSON JL, MILLS JL, HOLMES LB, OBER CL, AARONS J, JOVANOVIC L, KNOPP RH. Low Fetal Loss Rates after Ultrasound-Proved Viability in Early Pregnancy Obstetrical & Gynecological Survey. 43: 284-285. DOI: 10.1097/00006254-198805000-00006  0.083
2020 McKennan C, Ober C, Nicolae D. ESTIMATION AND INFERENCE IN METABOLOMICS WITH NON-RANDOM MISSING DATA AND LATENT FACTORS. The Annals of Applied Statistics. 14: 789-808. PMID 34221212 DOI: 10.1214/20-aoas1328  0.082
2023 Fang F, Zhou L, Perng W, Marsit CJ, Knight AK, Cardenas A, Aung MT, Hivert MF, Aris IM, Goodrich JM, Smith AK, Gaylord A, Fry RC, Oken E, O'Connor G, ... ... Ober C, et al. Evaluation of pediatric epigenetic clocks across multiple tissues. Clinical Epigenetics. 15: 142. PMID 37660147 DOI: 10.1186/s13148-023-01552-3  0.066
2018 Sirota M, Thomas CG, Liu R, Zuhl M, Banerjee P, Wong RJ, Quaintance CC, Leite R, Chubiz J, Anderson R, Chappell J, Kim M, Grobman W, Zhang G, Rokas A, ... ... Ober C, et al. Author Correction: Enabling precision medicine in neonatology, an integrated repository for preterm birth research. Scientific Data. 5: 3. PMID 30563979 DOI: 10.1038/S41597-018-0004-3  0.058
2020 Choi T, Devries M, Bacharier L, Busse W, Camargo CA, Cohen R, Demuri GP, Evans MD, Fitzpatrick AM, Gergen PJ, Grindle K, Gruchalla R, Hartert T, Hasegawa K, Khurana Hershey GK, ... ... Ober C, et al. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection. American Journal of Respiratory and Critical Care Medicine. PMID 33357024 DOI: 10.1164/rccm.202010-3753OC  0.054
2007 Anderson E, Dillie K, Evans M, Roberg K, Salazar L, DaSilva D, Pappas T, Tisler C, Gangnon R, Ober C, Gern J, Lemanske R. Children with Viral Respiratory Infections in the First Year of Life and Food Allergy at Age 5 Years Journal of Allergy and Clinical Immunology. 119: S168. DOI: 10.1016/J.Jaci.2006.12.021  0.037
1988 MILLS JL, KNOPP RH, SIMPSON JL, JOVANOVIC-PETERSON L, METZGER BE, HOLMES LB, AARONS JH, BROWN Z, REED GF, BIEBER FR, ALLEN MV, HOLZMAN I, OBER C, PETERSON CM, WITHIAM MJ, et al. Lack of Relation of Increased Malformation Rates in Infants of Diabetic Mothers to Glycemic Control during organogenesis Obstetrical & Gynecological Survey. 43: 673-674. DOI: 10.1097/00006254-198811000-00007  0.037
2017 Wise PH, Shaw GM, Druzin ML, Darmstadt GL, Quaintance C, Mäkinen E, Relman DA, Quake SR, Butte AJ, Angst MS, Muglia LJ, Macones G, Driscoll D, Ober C, Simpson JL, et al. Risky Business: Meeting the Structural Needs of Transdisciplinary Science. The Journal of Pediatrics. 191: 255-258. PMID 29173314 DOI: 10.1016/J.Jpeds.2017.08.072  0.011
Hide low-probability matches.