| Year |
Citation |
Score |
| 2024 |
Das A, Lakhani C, Terwagne C, Lin JT, Naito T, Raj T, Knowles DA. Leveraging functional annotations to map rare variants associated with Alzheimer's disease with gruyere. Medrxiv : the Preprint Server For Health Sciences. PMID 39677477 DOI: 10.1101/2024.12.06.24318577 |
0.334 |
|
| 2024 |
Farrell K, Humphrey J, Chang T, Zhao Y, Leung YY, Kuksa PP, Patil V, Lee WP, Kuzma AB, Valladares O, Cantwell LB, Wang H, Ravi A, De Sanctis C, Han N, ... ... Raj T, et al. Author Correction: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes. Nature Communications. 15: 9828. PMID 39537593 DOI: 10.1038/s41467-024-53617-3 |
0.699 |
|
| 2024 |
Farrell K, Humphrey J, Chang T, Zhao Y, Leung YY, Kuksa PP, Patil V, Lee WP, Kuzma AB, Valladares O, Cantwell LB, Wang H, Ravi A, De Sanctis C, Han N, ... ... Raj T, et al. Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes. Nature Communications. 15: 7880. PMID 39251599 DOI: 10.1038/s41467-024-52025-x |
0.74 |
|
| 2024 |
Ressler HW, Humphrey J, Vialle RA, Babrowicz B, Kandoi S, Raj T, Dickson DW, Ertekin-Taner N, Crary JF, Farrell K. MAPT haplotype-associated transcriptomic changes in progressive supranuclear palsy. Acta Neuropathologica Communications. 12: 135. PMID 39154163 DOI: 10.1186/s40478-024-01839-3 |
0.698 |
|
| 2024 |
Brown AL, Wilkins OG, Keuss MJ, Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H, ... ... Raj T, et al. Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. Nature. PMID 38890465 DOI: 10.1038/s41586-024-07577-9 |
0.719 |
|
| 2024 |
Navarro E, Efthymiou AG, Parks M, Riboldi GM, Vialle RA, Udine E, Muller BZ, Humphrey J, Allan A, Argyrou CC, Lopes KP, Münch A, Raymond D, Sachdev R, Shanker VL, ... ... Raj T, et al. G2019S variant is associated with transcriptional changes in Parkinson's disease human myeloid cells under proinflammatory environment. Biorxiv : the Preprint Server For Biology. PMID 38854101 DOI: 10.1101/2024.05.27.594821 |
0.67 |
|
| 2024 |
Koromina M, Ravi A, Panagiotaropoulou G, Schilder BM, Humphrey J, Braun A, Bidgeli T, Chatzinakos C, Coombes B, Kim J, Liu X, Terao C, O 'Connell KS, Adams M, Adolfsson R, ... ... Raj T, et al. Fine-mapping genomic loci refines bipolar disorder risk genes. Medrxiv : the Preprint Server For Health Sciences. PMID 38405768 DOI: 10.1101/2024.02.12.24302716 |
0.692 |
|
| 2024 |
Roussos P, Kosoy R, Fullard J, Bendl J, Kleopoulos S, Shao Z, Argyriou S, Mathur D, Vicari J, Ma Y, Humphrey J, Brophy E, Raj T, Katsel P, Voloudakis G, et al. Alzheimer's disease transcriptional landscape in ex-vivo human microglia. Research Square. PMID 38343831 DOI: 10.21203/rs.3.rs-3851590/v1 |
0.726 |
|
| 2024 |
Bryce-Smith S, Brown AL, Mehta PR, Mattedi F, Mikheenko A, Barattucci S, Zanovello M, Dattilo D, Yome M, Hill SE, Qi YA, Wilkins OG, Sun K, Ryadnov E, Wan Y, ... ... Raj T, et al. TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD. Biorxiv : the Preprint Server For Biology. PMID 38313254 DOI: 10.1101/2024.01.22.576625 |
0.748 |
|
| 2023 |
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, ... ... Raj T, et al. Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing. Medrxiv : the Preprint Server For Health Sciences. PMID 38076956 DOI: 10.1101/2023.12.01.23299073 |
0.745 |
|
| 2023 |
Snijders GJLJ, de Paiva Lopes K, Sneeboer MAM, Muller BZ, Gigase FAJ, Vialle RA, Missall R, Kubler R, Raj T, Humphrey J, de Witte LD. The human microglia responsome: a resource to better understand microglia states in health and disease. Biorxiv : the Preprint Server For Biology. PMID 37873223 DOI: 10.1101/2023.10.12.562067 |
0.727 |
|
| 2023 |
Fodder K, Murthy M, Rizzu P, Toomey CE, Hasan R, Humphrey J, Raj T, Lunnon K, Mill J, Heutink P, Lashley T, Bettencourt C. Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes. Acta Neuropathologica. PMID 37149835 DOI: 10.1007/s00401-023-02583-z |
0.711 |
|
| 2022 |
Humphrey J, Venkatesh S, Hasan R, Herb JT, de Paiva Lopes K, Küçükali F, Byrska-Bishop M, Evani US, Narzisi G, Fagegaltier D, Sleegers K, Phatnani H, Knowles DA, Fratta P, Raj T. Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes. Nature Neuroscience. PMID 36482247 DOI: 10.1038/s41593-022-01205-3 |
0.756 |
|
| 2022 |
Riboldi GM, Vialle RA, Navarro E, Udine E, de Paiva Lopes K, Humphrey J, Allan A, Parks M, Henderson B, Astudillo K, Argyrou C, Zhuang M, Sikder T, Oriol Narcis J, Kumar SD, ... ... Raj T, et al. Transcriptome deregulation of peripheral monocytes and whole blood in GBA-related Parkinson's disease. Molecular Neurodegeneration. 17: 52. PMID 35978378 DOI: 10.1186/s13024-022-00554-8 |
0.678 |
|
| 2022 |
Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K, Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, et al. Genetics of the human microglia regulome refines Alzheimer's disease risk loci. Nature Genetics. 54: 1145-1154. PMID 35931864 DOI: 10.1038/s41588-022-01149-1 |
0.732 |
|
| 2022 |
Bowles KR, Pugh DA, Liu Y, Patel T, Renton AE, Bandres-Ciga S, Gan-Or Z, Heutink P, Siitonen A, Bertelsen S, Cherry JD, Karch CM, Frucht SJ, Kopell BH, Peter I, ... ... Raj T, et al. 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes. Molecular Neurodegeneration. 17: 48. PMID 35841044 DOI: 10.1186/s13024-022-00551-x |
0.311 |
|
| 2022 |
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Raj T, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z |
0.714 |
|
| 2022 |
Vialle RA, de Paiva Lopes K, Bennett DA, Crary JF, Raj T. Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain. Nature Neuroscience. 25: 504-514. PMID 35288716 DOI: 10.1038/s41593-022-01031-7 |
0.393 |
|
| 2022 |
Brown AL, Wilkins OG, Keuss MJ, Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H, ... ... Raj T, et al. TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. Nature. PMID 35197628 DOI: 10.1038/s41586-022-04436-3 |
0.779 |
|
| 2022 |
Lopes KP, Snijders GJL, Humphrey J, Allan A, Sneeboer MAM, Navarro E, Schilder BM, Vialle RA, Parks M, Missall R, van Zuiden W, Gigase FAJ, Kübler R, van Berlekom AB, Hicks EM, ... ... Raj T, et al. Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies. Nature Genetics. 54: 4-17. PMID 34992268 DOI: 10.1038/s41588-021-00976-y |
0.733 |
|
| 2021 |
Navarro E, Udine E, de Paiva Lopes K, Parks M, Riboldi G, Schilder BM, Humphrey J, Snijders GJL, Vialle RA, Zhuang M, Sikder T, Argyrou C, Allan A, Chao MJ, Farrell K, ... ... Raj T, et al. Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells. Nature Aging. 1: 850-863. PMID 35005630 DOI: 10.1038/s43587-021-00110-x |
0.685 |
|
| 2021 |
Hasan R, Humphrey J, Bettencourt C, Newcombe J, Lashley T, Fratta P, Raj T. Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions. Acta Neuropathologica. PMID 34961893 DOI: 10.1007/s00401-021-02399-9 |
0.761 |
|
| 2021 |
Bowles KR, Pugh DA, Oja LM, Jadow BM, Farrell K, Whitney K, Sharma A, Cherry JD, Raj T, Pereira AC, Crary JF, Goate AM. Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD. Acta Neuropathologica. PMID 34874463 DOI: 10.1007/s00401-021-02392-2 |
0.308 |
|
| 2021 |
Schilder BM, Navarro E, Raj T. Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms. Neurobiology of Disease. 163: 105580. PMID 34871738 DOI: 10.1016/j.nbd.2021.105580 |
0.326 |
|
| 2021 |
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Raj T, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z |
0.723 |
|
| 2021 |
Schilder BM, Raj T. Fine-mapping of Parkinson's disease susceptibility loci identifies putative causal variants. Human Molecular Genetics. PMID 34617105 DOI: 10.1093/hmg/ddab294 |
0.371 |
|
| 2021 |
Schilder BM, Humphrey J, Raj T. echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline. Bioinformatics (Oxford, England). PMID 34529038 DOI: 10.1093/bioinformatics/btab658 |
0.651 |
|
| 2021 |
Bampton A, Gatt A, Humphrey J, Cappelli S, Bhattacharya D, Foti S, Brown AL, Asi Y, Low YH, Foiani M, Raj T, Buratti E, Fratta P, Lashley T. HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing. Acta Neuropathologica. PMID 34274995 DOI: 10.1007/s00401-021-02340-0 |
0.725 |
|
| 2021 |
Moon C, Schilder BM, Raj T, Huang KL. Phenome-wide and eQTL Associations of COVID-19 Genetic Risk Loci. Iscience. 102550. PMID 34027315 DOI: 10.1016/j.isci.2021.102550 |
0.343 |
|
| 2020 |
Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, ... ... Raj T, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741 |
0.758 |
|
| 2020 |
Ramdhani S, Navarro E, Udine E, Efthymiou AG, Schilder BM, Parks M, Goate A, Raj T. Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs. Plos Genetics. 16: e1008549. PMID 32012164 DOI: 10.1371/Journal.Pgen.1008549 |
0.399 |
|
| 2019 |
Li YI, Wong G, Humphrey J, Raj T. Prioritizing Parkinson's disease genes using population-scale transcriptomic data. Nature Communications. 10: 994. PMID 30824768 DOI: 10.1038/s41467-019-08912-9 |
0.702 |
|
| 2018 |
Ye CJ, Chen J, Villani AC, Gate RE, Subramaniam M, Bhangale T, Lee MN, Raj T, Raychowdhury R, Li W, Rogel N, Simmons S, Imboywa SH, Chipendo PI, McCabe C, et al. Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of transcripts under balancing selection. Genome Research. PMID 30446528 DOI: 10.1101/Gr.240390.118 |
0.37 |
|
| 2018 |
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, et al. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nature Genetics. PMID 30297968 DOI: 10.1038/S41588-018-0238-1 |
0.739 |
|
| 2018 |
Hefti MM, Farrell K, Kim S, Bowles KR, Fowkes ME, Raj T, Crary JF. High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development. Plos One. 13: e0195771. PMID 29634760 DOI: 10.1371/Journal.Pone.0195771 |
0.306 |
|
| 2017 |
Calderon D, Bhaskar A, Knowles DA, Golan D, Raj T, Fu AQ, Pritchard JK. Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. American Journal of Human Genetics. PMID 29106824 DOI: 10.1016/J.Ajhg.2017.09.009 |
0.335 |
|
| 2017 |
Pimenova AA, Raj T, Goate AM. Untangling Genetic Risk for Alzheimer's Disease. Biological Psychiatry. PMID 28666525 DOI: 10.1016/J.Biopsych.2017.05.014 |
0.387 |
|
| 2017 |
Huang KL, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SC, Harari O, Bertelsen S, Fairfax BP, Czajkowski J, Chouraki V, Grenier-Boley B, Bellenguez C, Deming Y, McKenzie A, ... Raj T, et al. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. Nature Neuroscience. PMID 28628103 DOI: 10.1038/Nn.4587 |
0.357 |
|
| 2015 |
Croteau-Chonka DC, Rogers AJ, Raj T, McGeachie MJ, Qiu W, Ziniti JP, Stubbs BJ, Liang L, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Stranger BE, Carey VJ, Raby BA. Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation. Plos One. 10: e0140758. PMID 26474488 DOI: 10.1371/Journal.Pone.0140758 |
0.311 |
|
| 2015 |
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, ... ... Raj T, et al. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. Jama Neurology. PMID 26366463 DOI: 10.1001/Jamaneurol.2015.1700 |
0.305 |
|
| 2015 |
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, ... ... Raj T, et al. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26092349 DOI: 10.1016/J.Jalz.2015.02.012 |
0.321 |
|
| 2014 |
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, et al. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature Neuroscience. 17: 1156-63. PMID 25129075 DOI: 10.1038/Nn.3786 |
0.312 |
|
| 2014 |
Hutchinson JN, Raj T, Fagerness J, Stahl E, Viloria FT, Gimelbrant A, Seddon J, Daly M, Chess A, Plenge R. Allele-specific methylation occurs at genetic variants associated with complex disease. Plos One. 9: e98464. PMID 24911414 DOI: 10.1371/Journal.Pone.0098464 |
0.311 |
|
| 2014 |
Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, et al. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science (New York, N.Y.). 344: 519-23. PMID 24786080 DOI: 10.1126/Science.1249547 |
0.33 |
|
| 2013 |
Stranger BE, Raj T. Genetics of human gene expression. Current Opinion in Genetics & Development. 23: 627-34. PMID 24238872 DOI: 10.1016/j.gde.2013.10.004 |
0.337 |
|
| 2013 |
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, ... Raj T, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. Jama. 309: 1483-92. PMID 23571587 DOI: 10.1001/Jama.2013.2973 |
0.366 |
|
| 2013 |
Raj T, Kuchroo M, Replogle JM, Raychaudhuri S, Stranger BE, De Jager PL. Common risk alleles for inflammatory diseases are targets of recent positive selection. American Journal of Human Genetics. 92: 517-29. PMID 23522783 DOI: 10.1016/J.Ajhg.2013.03.001 |
0.319 |
|
| 2012 |
Raj T, Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, De Jager PL. Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. American Journal of Human Genetics. 90: 720-6. PMID 22482808 DOI: 10.1016/J.Ajhg.2012.02.022 |
0.327 |
|
| 2012 |
Qutob N, Balloux F, Raj T, Liu H, Marion de Procé S, Trowsdale J, Manica A. Signatures of historical demography and pathogen richness on MHC class I genes. Immunogenetics. 64: 165-75. PMID 21947542 DOI: 10.1007/S00251-011-0576-Y |
0.537 |
|
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