Year |
Citation |
Score |
2024 |
Ko VI, Ong K, Cleveland DW, Yu H, Ravits JM. CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation. Neurobiology of Disease. 196: 106516. PMID 38677657 DOI: 10.1016/j.nbd.2024.106516 |
0.393 |
|
2023 |
Gao P, Zhang Q, Keely D, Cleveland DW, Ye Y, Zheng W, Shen M, Yu H. Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates. Journal of Medicinal Chemistry. PMID 37937963 DOI: 10.1021/acs.jmedchem.3c00490 |
0.37 |
|
2022 |
Lu S, Hu J, Arogundade OA, Goginashvili A, Vazquez-Sanchez S, Diedrich JK, Gu J, Blum J, Oung S, Ye Q, Yu H, Ravits J, Liu C, Yates JR, Cleveland DW. Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition. Nature Cell Biology. PMID 36075972 DOI: 10.1038/s41556-022-00988-8 |
0.404 |
|
2020 |
Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, Toprani D, Beccari MS, Yates JR, Da Cruz S, Newby JM, Lafarga M, Gladfelter AS, Villa E, Cleveland DW. HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science (New York, N.Y.). PMID 33335017 DOI: 10.1126/science.abb4309 |
0.389 |
|
2019 |
Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Huang TY, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130. PMID 31112137 DOI: 10.1172/Jci127695 |
0.373 |
|
2019 |
Gasset-Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, Shorter J, Da Cruz S, Cleveland DW. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. PMID 30853299 DOI: 10.1016/J.Neuron.2019.02.038 |
0.397 |
|
2018 |
Yu H, Cleveland DW. Tuning Apoptosis and Neuroinflammation: TBK1 Restrains RIPK1. Cell. 174: 1339-1341. PMID 30193106 DOI: 10.1016/j.cell.2018.08.035 |
0.38 |
|
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