Don Cleveland, PhD - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 

280 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, ... Cleveland DW, et al. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. PMID 31587919 DOI: 10.1016/j.neuron.2019.09.003  1
2019 Nechemia-Arbely Y, Miga KH, Shoshani O, Aslanian A, McMahon MA, Lee AY, Fachinetti D, Yates JR, Ren B, Cleveland DW. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nature Cell Biology. 21: 743-754. PMID 31160708 DOI: 10.1038/s41556-019-0331-4  0.68
2019 Ly P, Brunner SF, Shoshani O, Kim DH, Lan W, Pyntikova T, Flanagan AM, Behjati S, Page DC, Campbell PJ, Cleveland DW. Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements. Nature Genetics. PMID 30833795 DOI: 10.1038/s41588-019-0360-8  0.64
2019 Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, ... ... Cleveland DW, et al. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. Elife. 8. PMID 30747709 DOI: 10.7554/eLife.40811  1
2019 Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, ... ... Cleveland DW, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nature Neuroscience. PMID 30643298 DOI: 10.1038/s41593-018-0293-z  0.32
2019 Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nature Communications. 10: 175. PMID 30635586 DOI: 10.1038/s41467-018-08073-1  1
2018 López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Cleveland DW, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. PMID 30344044 DOI: 10.1016/j.neuron.2018.09.044  0.32
2018 Kim DH, Han JS, Ly P, Ye Q, McMahon MA, Myung K, Corbett KD, Cleveland DW. TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC. Nature Communications. 9: 4354. PMID 30341343 DOI: 10.1038/s41467-018-06774-1  0.68
2018 Gudimchuk N, Tarasovetc EV, Mustyatsa V, Drobyshev AL, Vitre B, Cleveland DW, Ataullakhanov FI, Grishchuk EL. Probing Mitotic CENP-E Kinesin with the Tethered Cargo Motion Assay and Laser Tweezers. Biophysical Journal. 114: 2640-2652. PMID 29874614 DOI: 10.1016/j.bpj.2018.04.017  0.92
2018 Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, et al. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. Acta Neuropathologica. PMID 29725819 DOI: 10.1007/s00401-018-1852-9  0.32
2018 Cheng W, Wang S, Mestre AA, Fu C, Makarem A, Xian F, Hayes LR, Lopez-Gonzalez R, Drenner K, Jiang J, Cleveland DW, Sun S. C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation. Nature Communications. 9: 51. PMID 29302060 DOI: 10.1038/s41467-017-02495-z  1
2017 Guo LY, Allu PK, Zandarashvili L, McKinley KL, Sekulic N, Dawicki-McKenna JM, Fachinetti D, Logsdon GA, Jamiolkowski RM, Cleveland DW, Cheeseman IM, Black BE. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications. 8: 15775. PMID 28598437 DOI: 10.1038/ncomms15775  1
2017 Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 28357566 DOI: 10.1007/s00401-017-1698-6  1
2017 Da Cruz S, Bui A, Saberi S, Lee SK, Stauffer J, McAlonis-Downes M, Schulte D, Pizzo DP, Parone PA, Cleveland DW, Ravits J. Misfolded SOD1 is not a primary component of sporadic ALS. Acta Neuropathologica. PMID 28247063 DOI: 10.1007/s00401-017-1688-8  0.32
2017 Nechemia-Arbely Y, Fachinetti D, Miga KH, Sekulic N, Soni GV, Kim DH, Wong AK, Lee AY, Nguyen K, Dekker C, Ren B, Black BE, Cleveland DW. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. The Journal of Cell Biology. PMID 28235947 DOI: 10.1083/jcb.201608083  1
2017 Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ. Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals. Developmental Cell. PMID 28132847 DOI: 10.1016/j.devcel.2016.12.022  1
2017 Fachinetti D, Logsdon GA, Abdullah A, Selzer EB, Cleveland DW, Black BE. CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres. Developmental Cell. 40: 104-113. PMID 28073008 DOI: 10.1016/j.devcel.2016.12.014  1
2016 Ly P, Teitz LS, Kim DH, Shoshani O, Skaletsky H, Fachinetti D, Page DC, Cleveland DW. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nature Cell Biology. PMID 27918550 DOI: 10.1038/ncb3450  0.68
2016 Hoffmann S, Dumont M, Barra V, Ly P, Nechemia-Arbely Y, McMahon MA, Hervé S, Cleveland DW, Fachinetti D. CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly. Cell Reports. 17: 2394-2404. PMID 27880912 DOI: 10.1016/j.celrep.2016.10.084  0.68
2016 Taylor JP, Brown RH, Cleveland DW. Decoding ALS: from genes to mechanism. Nature. 539: 197-206. PMID 27830784 DOI: 10.1038/nature20413  0.56
2016 Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, et al. Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine. PMID 27212019 DOI: 10.1016/j.freeradbiomed.2016.05.016  1
2016 Jiang J, Zhu Q, Gendron TF, Saberi S, McAlonis-Downes M, Seelman A, Stauffer JE, Jafar-Nejad P, Drenner K, Schulte D, Chun S, Sun S, Ling SC, Myers B, Engelhardt J, ... ... Cleveland DW, et al. Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. Neuron. PMID 27112497 DOI: 10.1016/j.neuron.2016.04.006  1
2016 Zhang YJ, Gendron TF, Grima JC, Sasaguri H, Jansen-West K, Xu YF, Katzman RB, Gass J, Murray ME, Shinohara M, Lin WL, Garrett A, Stankowski JN, Daughrity L, Tong J, ... ... Cleveland DW, et al. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nature Neuroscience. PMID 26998601 DOI: 10.1038/nn.4272  1
2015 Sun S, Sun Y, Ling SC, Ferraiuolo L, McAlonis-Downes M, Zou Y, Drenner K, Wang Y, Ditsworth D, Tokunaga S, Kopelevich A, Kaspar BK, Lagier-Tourenne C, Cleveland DW. Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621731 DOI: 10.1073/pnas.1520639112  1
2015 Rahdar M, McMahon MA, Prakash TP, Swayze EE, Bennett CF, Cleveland DW. Synthetic CRISPR RNA-Cas9-guided genome editing in human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26589814 DOI: 10.1073/pnas.1520883112  1
2015 Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. Chronic centrosome amplification without tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E6321-E6330. PMID 26578792 DOI: 10.1073/pnas.1519388112  1
2015 Kulukian A, Holland AJ, Vitre B, Naik S, Cleveland DW, Fuchs E. Epidermal development, growth control, and homeostasis in the face of centrosome amplification. Proceedings of the National Academy of Sciences of the United States of America. 112: E6311-20. PMID 26578791 DOI: 10.1073/pnas.1518376112  1
2015 Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathologica Communications. 3: 36. PMID 26108367 DOI: 10.1186/s40478-015-0212-4  0.32
2015 Fachinetti D, Han JS, McMahon MA, Ly P, Abdullah A, Wong AJ, Cleveland DW. DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function. Developmental Cell. 33: 314-27. PMID 25942623 DOI: 10.1016/j.devcel.2015.03.020  1
2015 Bertuzzi S, Cleveland DW. The curious incident of the translational dog that didn't bark. Trends in Cell Biology. 25: 187-9. PMID 25817192 DOI: 10.1016/j.tcb.2015.02.003  1
2015 Holland AJ, Reis RM, Niessen S, Pereira C, Andres DA, Spielmann HP, Cleveland DW, Desai A, Gassmann R. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Molecular Biology of the Cell. 26: 1845-56. PMID 25808490 DOI: 10.1091/mbc.E14-11-1560  1
2015 Israelson A, Ditsworth D, Sun S, Song S, Liang J, Hruska-Plochan M, McAlonis-Downes M, Abu-Hamad S, Zoltsman G, Shani T, Maldonado M, Bui A, Navarro M, Zhou H, Marsala M, ... ... Cleveland DW, et al. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. Neuron. 86: 218-32. PMID 25801706 DOI: 10.1016/j.neuron.2015.02.034  1
2015 Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, ... Cleveland DW, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nature Communications. 6: 6171. PMID 25625564 DOI: 10.1038/ncomms7171  1
2015 Litovsky SH, Kelly DR, Law MA, Dabal RJ, Daniel RL, Cleveland DS, Pearce FB. Shone variant with large eustachian valve: implication for repair and heart transplantation. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 24: 124-7. PMID 25455258 DOI: 10.1016/j.carpath.2014.10.002  0.4
2015 Tanner SM, Berryhill TF, Ellenburg JL, Jilling T, Cleveland DS, Lorenz RG, Martin CA. Pathogenesis of necrotizing enterocolitis: modeling the innate immune response. The American Journal of Pathology. 185: 4-16. PMID 25447054 DOI: 10.1016/j.ajpath.2014.08.028  0.4
2015 Holland AJ, Reis RM, Niessen S, Pereira C, Andres DA, Spielmann HP, Cleveland DW, Desai A, Gassmann R. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors Molecular Biology of the Cell. 26: 1845-1856. DOI: 10.1091/mbc.E14-11-1560)  1
2014 Han JS, Vitre B, Fachinetti D, Cleveland DW. Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: E4185-93. PMID 25246557 DOI: 10.1073/pnas.1416277111  1
2014 Traynor BJ, Cleveland DW. Special Issue on amyotrophic lateral sclerosis. Experimental Neurology. 262: 73-4. PMID 25158310 DOI: 10.1016/j.expneurol.2014.08.020  1
2014 Holland AJ, Cleveland DW. Polo-like kinase 4 inhibition: a strategy for cancer therapy? Cancer Cell. 26: 151-3. PMID 25117704 DOI: 10.1016/j.ccr.2014.07.017  1
2014 Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LE. The quantitative architecture of centromeric chromatin. Elife. 3: e02137. PMID 25027692  1
2014 Vitre B, Gudimchuk N, Borda R, Kim Y, Heuser JE, Cleveland DW, Grishchuk EL. Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E. Molecular Biology of the Cell. 25: 2272-81. PMID 24920822 DOI: 10.1091/mbc.E14-01-0698  1
2014 Mirzaa GM, Vitre B, Carpenter G, Abramowicz I, Gleeson JG, Paciorkowski AR, Cleveland DW, Dobyns WB, O'Driscoll M. Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism. Human Genetics. 133: 1023-39. PMID 24748105 DOI: 10.1007/s00439-014-1443-3  1
2014 Cortes CJ, Ling SC, Guo LT, Hung G, Tsunemi T, Ly L, Tokunaga S, Lopez E, Sopher BL, Bennett CF, Shelton GD, Cleveland DW, La Spada AR. Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. Neuron. 82: 295-307. PMID 24742458 DOI: 10.1016/j.neuron.2014.03.001  1
2014 Winkler EA, Sengillo JD, Sagare AP, Zhao Z, Ma Q, Zuniga E, Wang Y, Zhong Z, Sullivan JS, Griffin JH, Cleveland DW, Zlokovic BV. Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E1035-42. PMID 24591593 DOI: 10.1073/pnas.1401595111  1
2014 Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nature Neuroscience. 17: 513-21. PMID 24584051 DOI: 10.1038/nn.3668  1
2014 Lobsiger CS, Cleveland DW. Reply to Woodruff et al.: C1q and C3-dependent complement pathway activation does not contribute to disease in SOD1 mutant ALS mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E5. PMID 24555201 DOI: 10.1073/pnas.1321606111  1
2014 Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK. Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS. Proceedings of the National Academy of Sciences of the United States of America. 111: 829-32. PMID 24379375 DOI: 10.1073/pnas.1314085111  1
2014 Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LET. The quantitative architecture of centromeric chromatin Elife. 2014. DOI: 10.7554/eLife.02137  1
2013 Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, ... ... Cleveland DW, et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E4530-9. PMID 24170860 DOI: 10.1073/pnas.1318835110  1
2013 Lobsiger CS, Boillée S, Pozniak C, Khan AM, McAlonis-Downes M, Lewcock JW, Cleveland DW. C1q induction and global complement pathway activation do not contribute to ALS toxicity in mutant SOD1 mice. Proceedings of the National Academy of Sciences of the United States of America. 110: E4385-92. PMID 24170856 DOI: 10.1073/pnas.1318309110  1
2013 Silk AD, Zasadil LM, Holland AJ, Vitre B, Cleveland DW, Weaver BA. Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: E4134-41. PMID 24133140 DOI: 10.1073/pnas.1317042110  1
2013 Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2148-59. PMID 24008656 DOI: 10.1038/mt.2013.211  1
2013 Gudimchuk N, Vitre B, Kim Y, Kiyatkin A, Cleveland DW, Ataullakhanov FI, Grishchuk EL. Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips. Nature Cell Biology. 15: 1079-88. PMID 23955301 DOI: 10.1038/ncb2831  1
2013 Ling SC, Polymenidou M, Cleveland DW. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron. 79: 416-38. PMID 23931993 DOI: 10.1016/j.neuron.2013.07.033  1
2013 Earnshaw WC, Cleveland DW. CENP-A and the CENP nomenclature: response to Talbert and Henikoff. Trends in Genetics : Tig. 29: 500-2. PMID 23910159 DOI: 10.1016/j.tig.2013.06.008  1
2013 Fachinetti D, Folco HD, Nechemia-Arbely Y, Valente LP, Nguyen K, Wong AJ, Zhu Q, Holland AJ, Desai A, Jansen LE, Cleveland DW. A two-step mechanism for epigenetic specification of centromere identity and function. Nature Cell Biology. 15: 1056-66. PMID 23873148 DOI: 10.1038/ncb2805  1
2013 Han JS, Holland AJ, Fachinetti D, Kulukian A, Cetin B, Cleveland DW. Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. Molecular Cell. 51: 92-104. PMID 23791783 DOI: 10.1016/j.molcel.2013.05.019  1
2013 Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, ... ... Cleveland DW, et al. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 101-6. PMID 23580138 DOI: 10.1007/s10577-013-9347-y  1
2013 Kang SH, Li Y, Fukaya M, Lorenzini I, Cleveland DW, Ostrow LW, Rothstein JD, Bergles DE. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nature Neuroscience. 16: 571-9. PMID 23542689 DOI: 10.1038/nn.3357  1
2013 Parone PA, Da Cruz S, Han JS, McAlonis-Downes M, Vetto AP, Lee SK, Tseng E, Cleveland DW. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4657-71. PMID 23486940 DOI: 10.1523/JNEUROSCI.1119-12.2013  1
2013 Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, ... ... Cleveland DW, et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America. 110: E736-45. PMID 23382207 DOI: 10.1073/pnas.1222809110  1
2012 Holland AJ, Fachinetti D, Zhu Q, Bauer M, Verma IM, Nigg EA, Cleveland DW. The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes & Development. 26: 2684-9. PMID 23249732 DOI: 10.1101/gad.207027.112  1
2012 Sun S, Cleveland DW. TDP-43 toxicity and the usefulness of junk. Nature Genetics. 44: 1289-91. PMID 23192178 DOI: 10.1038/ng.2473  1
2012 Holland AJ, Cleveland DW. The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation. The Journal of Clinical Investigation. 122: 4325-8. PMID 23187131 DOI: 10.1172/JCI66420  1
2012 Holland AJ, Fachinetti D, Han JS, Cleveland DW. Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 109: E3350-7. PMID 23150568 DOI: 10.1073/pnas.1216880109  1
2012 Holland AJ, Cleveland DW. Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements. Nature Medicine. 18: 1630-8. PMID 23135524 DOI: 10.1038/nm.2988  1
2012 Vitre BD, Cleveland DW. Centrosomes, chromosome instability (CIN) and aneuploidy. Current Opinion in Cell Biology. 24: 809-15. PMID 23127609 DOI: 10.1016/j.ceb.2012.10.006  1
2012 Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, ... ... Cleveland DW, et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nature Neuroscience. 15: 1488-97. PMID 23023293 DOI: 10.1038/nn.3230  1
2012 Yu D, Pendergraff H, Liu J, Kordasiewicz HB, Cleveland DW, Swayze EE, Lima WF, Crooke ST, Prakash TP, Corey DR. Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression. Cell. 150: 895-908. PMID 22939619 DOI: 10.1016/j.cell.2012.08.002  1
2012 Hefferan MP, Galik J, Kakinohana O, Sekerkova G, Santucci C, Marsala S, Navarro R, Hruska-Plochan M, Johe K, Feldman E, Cleveland DW, Marsala M. Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation. Plos One. 7: e42614. PMID 22916141 DOI: 10.1371/journal.pone.0042614  1
2012 Kordasiewicz HB, Stanek LM, Wancewicz EV, Mazur C, McAlonis MM, Pytel KA, Artates JW, Weiss A, Cheng SH, Shihabuddin LS, Hung G, Bennett CF, Cleveland DW. Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron. 74: 1031-44. PMID 22726834 DOI: 10.1016/j.neuron.2012.05.009  1
2012 Polymenidou M, Cleveland DW. Prion-like spread of protein aggregates in neurodegeneration. The Journal of Experimental Medicine. 209: 889-93. PMID 22566400 DOI: 10.1084/jem.20120741  1
2012 Holland AJ, Cleveland DW. Losing balance: the origin and impact of aneuploidy in cancer. Embo Reports. 13: 501-14. PMID 22565320 DOI: 10.1038/embor.2012.55  1
2012 Nechemia-Arbely Y, Fachinetti D, Cleveland DW. Replicating centromeric chromatin: spatial and temporal control of CENP-A assembly. Experimental Cell Research. 318: 1353-60. PMID 22561213 DOI: 10.1016/j.yexcr.2012.04.007  1
2012 Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW. Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metabolism. 15: 778-86. PMID 22560226 DOI: 10.1016/j.cmet.2012.03.019  1
2012 Kolano A, Brunet S, Silk AD, Cleveland DW, Verlhac MH. Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proceedings of the National Academy of Sciences of the United States of America. 109: E1858-67. PMID 22552228 DOI: 10.1073/pnas.1204686109  1
2012 Holland AJ, Fachinetti D, Da Cruz S, Zhu Q, Vitre B, Lince-Faria M, Chen D, Parish N, Verma IM, Bettencourt-Dias M, Cleveland DW. Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis. Molecular Biology of the Cell. 23: 1838-45. PMID 22456511 DOI: 10.1091/mbc.E11-12-1043  1
2012 Polymenidou M, Lagier-Tourenne C, Hutt KR, Bennett CF, Cleveland DW, Yeo GW. Misregulated RNA processing in amyotrophic lateral sclerosis. Brain Research. 1462: 3-15. PMID 22444279 DOI: 10.1016/j.brainres.2012.02.059  1
2012 Kordasiewicz HB, Stanek LM, Wancewicz EV, Mazur C, McAlonis MM, Pytel KA, Artates JW, Weiss A, Cheng SH, Shihabuddin LS, Hung G, Bennett CF, Cleveland DW, Skaper SD. Research highlights making sense out of antisense in huntington's disease Cns and Neurological Disorders - Drug Targets. 11: 647-648. DOI: 10.2174/187152712803581038  1
2011 Polymenidou M, Cleveland DW. The seeds of neurodegeneration: prion-like spreading in ALS. Cell. 147: 498-508. PMID 22036560 DOI: 10.1016/j.cell.2011.10.011  1
2011 Kolodner RD, Cleveland DW, Putnam CD. Cancer. Aneuploidy drives a mutator phenotype in cancer. Science (New York, N.Y.). 333: 942-3. PMID 21852477 DOI: 10.1126/science.1211154  1
2011 Da Cruz S, Cleveland DW. Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Current Opinion in Neurobiology. 21: 904-19. PMID 21813273 DOI: 10.1016/j.conb.2011.05.029  1
2011 Vande Velde C, McDonald KK, Boukhedimi Y, McAlonis-Downes M, Lobsiger CS, Bel Hadj S, Zandona A, Julien JP, Shah SB, Cleveland DW. Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. Plos One. 6: e22031. PMID 21779368 DOI: 10.1371/journal.pone.0022031  1
2011 Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, ... ... Cleveland DW, et al. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nature Neuroscience. 14: 459-68. PMID 21358643 DOI: 10.1038/nn.2779  1
2011 Black BE, Cleveland DW. Epigenetic centromere propagation and the nature of CENP-a nucleosomes. Cell. 144: 471-9. PMID 21335232 DOI: 10.1016/j.cell.2011.02.002  1
2010 Black BE, Jansen LE, Foltz DR, Cleveland DW. Centromere identity, function, and epigenetic propagation across cell divisions. Cold Spring Harbor Symposia On Quantitative Biology. 75: 403-18. PMID 21467140 DOI: 10.1101/sqb.2010.75.038  1
2010 Li Q, Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, Capaldi RA, Cleveland DW, Miller TM. ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import. Proceedings of the National Academy of Sciences of the United States of America. 107: 21146-51. PMID 21078990 DOI: 10.1073/pnas.1014862107  1
2010 Hatch EM, Kulukian A, Holland AJ, Cleveland DW, Stearns T. Cep152 interacts with Plk4 and is required for centriole duplication. The Journal of Cell Biology. 191: 721-9. PMID 21059850 DOI: 10.1083/jcb.201006049  1
2010 Cetin B, Cleveland DW. How to survive aneuploidy. Cell. 143: 27-9. PMID 20887888 DOI: 10.1016/j.cell.2010.09.030  1
2010 Lan W, Cleveland DW. Multiclassifier proteomics to define complexes yields new chromosomal proteins. Developmental Cell. 19: 356-9. PMID 20833356 DOI: 10.1016/j.devcel.2010.08.017  1
2010 Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW. Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron. 67: 575-87. PMID 20797535 DOI: 10.1016/j.neuron.2010.07.019  1
2010 Lagier-Tourenne C, Cleveland DW. Neurodegeneration: An expansion in ALS genetics. Nature. 466: 1052-3. PMID 20740002 DOI: 10.1038/4661052a  1
2010 Kim Y, Holland AJ, Lan W, Cleveland DW. Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell. 142: 444-55. PMID 20691903 DOI: 10.1016/j.cell.2010.06.039  1
2010 Holland AJ, Lan W, Cleveland DW. Centriole duplication: A lesson in self-control. Cell Cycle (Georgetown, Tex.). 9: 2731-6. PMID 20647763 DOI: 10.4161/cc.9.14.12184  1
2010 Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proceedings of the National Academy of Sciences of the United States of America. 107: 13318-23. PMID 20624952 DOI: 10.1073/pnas.1008227107  1
2010 Lan W, Cleveland DW. A chemical tool box defines mitotic and interphase roles for Mps1 kinase. The Journal of Cell Biology. 190: 21-4. PMID 20624898 DOI: 10.1083/jcb.201006080  1
2010 Gassmann R, Holland AJ, Varma D, Wan X, Civril F, Cleveland DW, Oegema K, Salmon ED, Desai A. Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes & Development. 24: 957-71. PMID 20439434 DOI: 10.1101/gad.1886810  1
2010 Lagier-Tourenne C, Polymenidou M, Cleveland DW. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Human Molecular Genetics. 19: R46-64. PMID 20400460 DOI: 10.1093/hmg/ddq137  1
2010 Radulescu AE, Cleveland DW. NuMA after 30 years: the matrix revisited. Trends in Cell Biology. 20: 214-22. PMID 20137953 DOI: 10.1016/j.tcb.2010.01.003  1
2010 Holland AJ, Lan W, Niessen S, Hoover H, Cleveland DW. Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. The Journal of Cell Biology. 188: 191-8. PMID 20100909 DOI: 10.1083/jcb.200911102  1
2010 Gurden MD, Holland AJ, van Zon W, Tighe A, Vergnolle MA, Andres DA, Spielmann HP, Malumbres M, Wolthuis RM, Cleveland DW, Taylor SS. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. Journal of Cell Science. 123: 321-30. PMID 20053638 DOI: 10.1242/jcs.062075  1
2010 Lobsiger CS, Cleveland DW. Neurofilaments: Organization and Function in Neurons Encyclopedia of Neuroscience. 433-436. DOI: 10.1016/B978-008045046-9.00728-2  1
2010 Vande Velde C, Cleveland DW. Amyotrophic Lateral Sclerosis (ALS): Disease Mechanisms Encyclopedia of Neuroscience. 369-373. DOI: 10.1016/B978-008045046-9.00510-6  1
2009 Ilieva H, Polymenidou M, Cleveland DW. Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. The Journal of Cell Biology. 187: 761-72. PMID 19951898 DOI: 10.1083/jcb.200908164  1
2009 Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, ... ... Cleveland DW, et al. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. The Journal of Clinical Investigation. 119: 3437-49. PMID 19841542 DOI: 10.1172/JCI38476  1
2009 Zeitlin SG, Baker NM, Chapados BR, Soutoglou E, Wang JY, Berns MW, Cleveland DW. Double-strand DNA breaks recruit the centromeric histone CENP-A. Proceedings of the National Academy of Sciences of the United States of America. 106: 15762-7. PMID 19717431 DOI: 10.1073/pnas.0908233106  1
2009 Samoshkin A, Arnaoutov A, Jansen LE, Ouspenski I, Dye L, Karpova T, McNally J, Dasso M, Cleveland DW, Strunnikov A. Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. Plos One. 4: e6831. PMID 19714251 DOI: 10.1371/journal.pone.0006831  1
2009 Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nature Reviews. Molecular Cell Biology. 10: 478-87. PMID 19546858 DOI: 10.1038/nrm2718  1
2009 Weaver BA, Cleveland DW. The role of aneuploidy in promoting and suppressing tumors. The Journal of Cell Biology. 185: 935-7. PMID 19528293 DOI: 10.1083/jcb.200905098  1
2009 Foltz DR, Jansen LE, Bailey AO, Yates JR, Bassett EA, Wood S, Black BE, Cleveland DW. Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP. Cell. 137: 472-84. PMID 19410544 DOI: 10.1016/j.cell.2009.02.039  1
2009 Lagier-Tourenne C, Cleveland DW. Rethinking ALS: the FUS about TDP-43. Cell. 136: 1001-4. PMID 19303844 DOI: 10.1016/j.cell.2009.03.006  1
2009 Silk AD, Holland AJ, Cleveland DW. Requirements for NuMA in maintenance and establishment of mammalian spindle poles. The Journal of Cell Biology. 184: 677-90. PMID 19255246 DOI: 10.1083/jcb.200810091  1
2009 Lobsiger CS, Boillee S, McAlonis-Downes M, Khan AM, Feltri ML, Yamanaka K, Cleveland DW. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 4465-70. PMID 19251638 DOI: 10.1073/pnas.0813339106  1
2009 Garcia ML, Rao MV, Fujimoto J, Garcia VB, Shah SB, Crum J, Gotow T, Uchiyama Y, Ellisman M, Calcutt NA, Cleveland DW. Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1277-84. PMID 19193875 DOI: 10.1523/JNEUROSCI.3765-08.2009  1
2009 Cleveland DW, Yamanaka K, Bomont P. Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway. Human Molecular Genetics. 18: 1384-94. PMID 19168853 DOI: 10.1093/hmg/ddp044  1
2009 Kulukian A, Han JS, Cleveland DW. Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Developmental Cell. 16: 105-17. PMID 19154722 DOI: 10.1016/j.devcel.2008.11.005  1
2008 Weaver BA, Cleveland DW. The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell. 14: 431-3. PMID 19061834 DOI: 10.1016/j.ccr.2008.11.011  1
2008 Weaver BA, Silk AD, Cleveland DW. Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 30: 453. PMID 18791276 DOI: 10.3233/CLO-2008-0445  1
2008 Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proceedings of the National Academy of Sciences of the United States of America. 105: 12599-604. PMID 18719118 DOI: 10.1073/pnas.0805422105  1
2008 Holland AJ, Cleveland DW. Beyond genetics: surprising determinants of cell fate in antitumor drugs. Cancer Cell. 14: 103-5. PMID 18691543 DOI: 10.1016/j.ccr.2008.07.010  1
2008 Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. Plos One. 3: e2849. PMID 18682740 DOI: 10.1371/journal.pone.0002849  1
2008 Dequen F, Bomont P, Gowing G, Cleveland DW, Julien JP. Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1. Journal of Neurochemistry. 107: 253-64. PMID 18680552 DOI: 10.1111/j.1471-4159.2008.05601.x  1
2008 Polymenidou M, Cleveland DW. Motor neuron disease: The curious ways of ALS. Nature. 454: 284-5. PMID 18633404 DOI: 10.1038/454284a  1
2008 Jelluma N, Brenkman AB, McLeod I, Yates JR, Cleveland DW, Medema RH, Kops GJ. Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. Plos One. 3: e2415. PMID 18545697 DOI: 10.1371/journal.pone.0002415  1
2008 Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LS. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 7594-9. PMID 18492803 DOI: 10.1073/pnas.0802556105  1
2008 Kim Y, Heuser JE, Waterman CM, Cleveland DW. CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. The Journal of Cell Biology. 181: 411-9. PMID 18443223 DOI: 10.1083/jcb.200802189  1
2008 Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV. ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nature Neuroscience. 11: 420-2. PMID 18344992 DOI: 10.1038/nn2073  1
2008 Vande Velde C, Miller TM, Cashman NR, Cleveland DW. Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 105: 4022-7. PMID 18296640 DOI: 10.1073/pnas.0712209105  1
2008 Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nature Neuroscience. 11: 251-3. PMID 18246065 DOI: 10.1038/nn2047  1
2008 Boillée S, Cleveland DW. Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1. The Journal of Clinical Investigation. 118: 474-8. PMID 18219386 DOI: 10.1172/JCI34613  1
2008 Detmer SA, Vande Velde C, Cleveland DW, Chan DC. Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A. Human Molecular Genetics. 17: 367-75. PMID 17959936 DOI: 10.1093/hmg/ddm314  1
2007 Weaver BA, Cleveland DW. Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Research. 67: 10103-5. PMID 17974949 DOI: 10.1158/0008-5472.CAN-07-2266  1
2007 Lobsiger CS, Cleveland DW. Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease. Nature Neuroscience. 10: 1355-60. PMID 17965655 DOI: 10.1038/nn1988  1
2007 Gruzman A, Wood WL, Alpert E, Prasad MD, Miller RG, Rothstein JD, Bowser R, Hamilton R, Wood TD, Cleveland DW, Lingappa VR, Liu J. Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12524-9. PMID 17636119 DOI: 10.1073/pnas.0705044104  1
2007 Bailey AO, Miller TM, Dong MQ, Vande Velde C, Cleveland DW, Yates JR. RCADiA: simple automation platform for comparative multidimensional protein identification technology. Analytical Chemistry. 79: 6410-8. PMID 17616168 DOI: 10.1021/ac070585g  1
2007 Conde e Silva N, Black BE, Sivolob A, Filipski J, Cleveland DW, Prunell A. CENP-A-containing nucleosomes: easier disassembly versus exclusive centromeric localization. Journal of Molecular Biology. 370: 555-73. PMID 17524417 DOI: 10.1016/j.jmb.2007.04.064  1
2007 Weaver BA, Cleveland DW. Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (New York, N.Y.). 316: 982; author reply 98. PMID 17510348 DOI: 10.1126/science.1139523  1
2007 Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nature Medicine. 13: 754-9. PMID 17486090 DOI: 10.1038/nm1559  1
2007 Lobsiger CS, Boillée S, Cleveland DW. Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. Proceedings of the National Academy of Sciences of the United States of America. 104: 7319-26. PMID 17463094 DOI: 10.1073/pnas.0702230104  1
2007 Black BE, Brock MA, Bédard S, Woods VL, Cleveland DW. An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 104: 5008-13. PMID 17360341 DOI: 10.1073/pnas.0700390104  1
2007 Jansen LE, Black BE, Foltz DR, Cleveland DW. Propagation of centromeric chromatin requires exit from mitosis. The Journal of Cell Biology. 176: 795-805. PMID 17339380 DOI: 10.1083/jcb.200701066  1
2007 Black BE, Jansen LE, Maddox PS, Foltz DR, Desai AB, Shah JV, Cleveland DW. Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Molecular Cell. 25: 309-22. PMID 17244537 DOI: 10.1016/j.molcel.2006.12.018  1
2007 Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 11: 25-36. PMID 17189716 DOI: 10.1016/j.ccr.2006.12.003  1
2007 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? [Current Opinion in Cell Biology 2006, 18:658-667] (DOI:10.1016/j.ceb.2006.10.002) Current Opinion in Cell Biology. 19: 246. DOI: 10.1016/j.ceb.2007.02.017  1
2006 Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19546-51. PMID 17164329 DOI: 10.1073/pnas.0609411103  1
2006 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? Current Opinion in Cell Biology. 18: 658-67. PMID 17046232 DOI: 10.1016/j.ceb.2006.10.002  1
2006 Ross CA, Cleveland DW. Intercellular miscommunication in polyglutamine pathogenesis. Nature Neuroscience. 9: 1205-6. PMID 17001335 DOI: 10.1038/nn1006-1205  1
2006 Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, Mouradian MM, Przedborski S, Trapp BD, Wyss-Coray T, Yong VW. Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. Journal of Neuroimmunology. 176: 198-215. PMID 16983747 DOI: 10.1016/j.jneuroim.2006.03.027  1
2006 Miller TM, Smith RA, Cleveland DW. Amyotrophic lateral sclerosis and gene therapy. Nature Clinical Practice. Neurology. 2: 462-3. PMID 16932606 DOI: 10.1038/ncpneuro0270  1
2006 Weaver BA, Silk AD, Cleveland DW. Cell biology: nondisjunction, aneuploidy and tetraploidy. Nature. 442: E9-10; discussion E1. PMID 16915240 DOI: 10.1038/nature05139  1
2006 Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, Bennett CF, Cleveland DW. Antisense oligonucleotide therapy for neurodegenerative disease. The Journal of Clinical Investigation. 116: 2290-6. PMID 16878173 DOI: 10.1172/JCI25424  1
2006 Yamanaka K, Miller TM, McAlonis-Downes M, Chun SJ, Cleveland DW. Progressive spinal axonal degeneration and slowness in ALS2-deficient mice. Annals of Neurology. 60: 95-104. PMID 16802286 DOI: 10.1002/ana.20888  1
2006 Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW. Onset and progression in inherited ALS determined by motor neurons and microglia. Science (New York, N.Y.). 312: 1389-92. PMID 16741123 DOI: 10.1126/science.1123511  1
2006 Eymard-Pierre E, Yamanaka K, Haeussler M, Kress W, Gauthier-Barichard F, Combes P, Cleveland DW, Boespflug-Tanguy O. Novel missense mutation in ALS2 gene results in infantile ascending hereditary spastic paralysis. Annals of Neurology. 59: 976-80. PMID 16718699 DOI: 10.1002/ana.20879  1
2006 Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW. The human CENP-A centromeric nucleosome-associated complex. Nature Cell Biology. 8: 458-69. PMID 16622419 DOI: 10.1038/ncb1397  1
2006 Wang Z, Shah JV, Berns MW, Cleveland DW. In vivo quantitative studies of dynamic intracellular processes using fluorescence correlation spectroscopy. Biophysical Journal. 91: 343-51. PMID 16603490 DOI: 10.1529/biophysj.105.077891  1
2006 Garcia ML, Singleton AB, Hernandez D, Ward CM, Evey C, Sapp PA, Hardy J, Brown RH, Cleveland DW. Mutations in neurofilament genes are not a significant primary cause of non-SOD1-mediated amyotrophic lateral sclerosis. Neurobiology of Disease. 21: 102-9. PMID 16084104 DOI: 10.1016/j.nbd.2005.06.016  1
2005 Yamanaka K, Cleveland DW. Determinants of rapid disease progression in ALS. Neurology. 65: 1859-60. PMID 16380607 DOI: 10.1212/01.wnl.0000192717.25980.b5  1
2005 Bomont P, Maddox P, Shah JV, Desai AB, Cleveland DW. Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F. The Embo Journal. 24: 3927-39. PMID 16252009 DOI: 10.1038/sj.emboj.7600848  1
2005 Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nature Reviews. Cancer. 5: 773-85. PMID 16195750 DOI: 10.1038/nrc1714  0.92
2005 Mao Y, Desai A, Cleveland DW. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. The Journal of Cell Biology. 170: 873-80. PMID 16144904 DOI: 10.1083/jcb.200505040  1
2005 Weaver BA, Cleveland DW. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell. 8: 7-12. PMID 16023594 DOI: 10.1016/j.ccr.2005.06.011  1
2005 Liu J, Shinobu LA, Ward CM, Young D, Cleveland DW. Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 93: 875-82. PMID 15857390 DOI: 10.1111/j.1471-4159.2005.03054.x  1
2005 Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Annals of Neurology. 57: 773-6. PMID 15852369 DOI: 10.1002/ana.20453  1
2005 Kops GJ, Kim Y, Weaver BA, Mao Y, McLeod I, Yates JR, Tagaya M, Cleveland DW. ZW10 links mitotic checkpoint signaling to the structural kinetochore. The Journal of Cell Biology. 169: 49-60. PMID 15824131 DOI: 10.1083/jcb.200411118  1
2005 Miller TM, Cleveland DW. Medicine. Treating neurodegenerative diseases with antibiotics. Science (New York, N.Y.). 307: 361-2. PMID 15661995 DOI: 10.1126/science.1109027  1
2004 Wang H, Hu X, Ding X, Dou Z, Yang Z, Shaw AW, Teng M, Cleveland DW, Goldberg ML, Niu L, Yao X. Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. The Journal of Biological Chemistry. 279: 54590-8. PMID 15485811 DOI: 10.1074/jbc.M407588200  1
2004 Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/jcb.200408113  1
2004 Black BE, Foltz DR, Chakravarthy S, Luger K, Woods VL, Cleveland DW. Structural determinants for generating centromeric chromatin. Nature. 430: 578-82. PMID 15282608 DOI: 10.1038/nature02766  1
2004 Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 43: 5-17. PMID 15233913 DOI: 10.1016/j.neuron.2004.06.016  1
2004 Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annual Review of Neuroscience. 27: 723-49. PMID 15217349 DOI: 10.1146/annurev.neuro.27.070203.144244  1
2004 Shah JV, Botvinick E, Bonday Z, Furnari F, Berns M, Cleveland DW. Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Current Biology : Cb. 14: 942-52. PMID 15182667 DOI: 10.1016/j.cub.2004.05.046  1
2004 Kops GJ, Foltz DR, Cleveland DW. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 101: 8699-704. PMID 15159543 DOI: 10.1073/pnas.0401142101  0.8
2004 Boillée S, Cleveland DW. Gene therapy for ALS delivers. Trends in Neurosciences. 27: 235-8. PMID 15111001 DOI: 10.1016/j.tins.2004.03.002  1
2003 Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, Ward CM, Crawford TO, Gotow T, Uchiyama Y, Ellisman MH, Calcutt NA, Cleveland DW. NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth. The Journal of Cell Biology. 163: 1011-20. PMID 14662745 DOI: 10.1083/jcb.200308159  1
2003 Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (New York, N.Y.). 302: 113-7. PMID 14526083 DOI: 10.1126/science.1086071  1
2003 Miller TM, Cleveland DW. Has gene therapy for ALS arrived? Nature Medicine. 9: 1256-7. PMID 14520369 DOI: 10.1038/nm1003-1256  1
2003 Weaver BA, Bonday ZQ, Putkey FR, Kops GJ, Silk AD, Cleveland DW. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. The Journal of Cell Biology. 162: 551-63. PMID 12925705 DOI: 10.1083/jcb.200303167  1
2003 Mao Y, Abrieu A, Cleveland DW. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell. 114: 87-98. PMID 12859900  0.6
2003 Xia CH, Roberts EA, Her LS, Liu X, Williams DS, Cleveland DW, Goldstein LS. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. The Journal of Cell Biology. 161: 55-66. PMID 12682084 DOI: 10.1083/jcb.200301026  1
2003 Cleveland DW, Mao Y, Sullivan KF. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell. 112: 407-21. PMID 12600307  0.6
2002 Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, Cleveland DW. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Developmental Cell. 3: 351-65. PMID 12361599 DOI: 10.1016/S1534-5807(02)00255-1  1
2002 Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron. 35: 1067-83. PMID 12354397 DOI: 10.1016/S0896-6273(02)00905-4  1
2002 Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. The Journal of Cell Biology. 158: 681-93. PMID 12186852 DOI: 10.1083/jcb.200202037  1
2002 Subramaniam JR, Lyons WE, Liu J, Bartnikas TB, Rothstein J, Price DL, Cleveland DW, Gitlin JD, Wong PC. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nature Neuroscience. 5: 301-7. PMID 11889469 DOI: 10.1038/nn823  1
2002 Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proceedings of the National Academy of Sciences of the United States of America. 99: 1604-9. PMID 11818550 DOI: 10.1073/pnas.032539299  1
2002 Shah JV, Cleveland DW. Slow axonal transport: fast motors in the slow lane. Current Opinion in Cell Biology. 14: 58-62. PMID 11792545 DOI: 10.1016/S0955-0674(01)00294-0  1
2002 Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. The Journal of Biological Chemistry. 277: 4644-8. PMID 11733539 DOI: 10.1074/jbc.M110913200  1
2001 Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nature Reviews. Neuroscience. 2: 806-19. PMID 11715057 DOI: 10.1038/35097565  1
2001 Skene JP, Cleveland DW. Hypoxia and Lou Gehrig. Nature Genetics. 28: 107-8. PMID 11381249 DOI: 10.1038/88805  1
2001 Kato S, Nakashima K, Horiuchi S, Nagai R, Cleveland DW, Liu J, Hirano A, Takikawa M, Kato M, Nakano I, Sakoda S, Asayama K, Ohama E. Formation of advanced glycation end-product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and transgenic mice expressing human SOD1 gene mutation. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 21: 67-81. PMID 11304045 DOI: 10.1046/j.1440-1789.2001.00359.x  1
2001 Kahana JA, Cleveland DW. Cell cycle. Some importin news about spindle assembly. Science (New York, N.Y.). 291: 1718-9. PMID 11253198 DOI: 10.1126/science.1059765  1
2001 Garcia ML, Cleveland DW. Going new places using an old MAP: tau, microtubules and human neurodegenerative disease. Current Opinion in Cell Biology. 13: 41-8. PMID 11163132 DOI: 10.1016/S0955-0674(00)00172-1  1
2000 Kato S, Takikawa M, Nakashima K, Hirano A, Cleveland DW, Kusaka H, Shibata N, Kato M, Nakano I, Ohama E. New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 163-84. PMID 11464950 DOI: 10.1080/14660820050515160  1
2000 Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. The value of transgenic models for the study of neurodegenerative diseases. Annals of the New York Academy of Sciences. 920: 179-91. PMID 11193148  1
2000 Shah JV, Cleveland DW. Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell. 103: 997-1000. PMID 11163175 DOI: 10.1016/S0092-8674(00)00202-6  1
2000 Cleveland DW, Liu J. Oxidation versus aggregation - how do SOD1 mutants cause ALS? Nature Medicine. 6: 1320-1. PMID 11100110 DOI: 10.1038/82122  1
2000 Pasinelli P, Houseweart MK, Brown RH, Cleveland DW. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 13901-6. PMID 11095709 DOI: 10.1073/pnas.240305897  1
2000 Sánchez I, Hassinger L, Sihag RK, Cleveland DW, Mohan P, Nixon RA. Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation. The Journal of Cell Biology. 151: 1013-24. PMID 11086003 DOI: 10.1083/jcb.151.5.1013  1
2000 Kato S, Horiuchi S, Liu J, Cleveland DW, Shibata N, Nakashima K, Nagai R, Hirano A, Takikawa M, Kato M, Nakano I, Ohama E. Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation. Acta Neuropathologica. 100: 490-505. PMID 11045671 DOI: 10.1007/s004010000226  1
2000 Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nature Cell Biology. 2: 484-91. PMID 10934468 DOI: 10.1038/35019518  0.6
2000 Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. The Journal of Cell Biology. 150: 1-11. PMID 10893249 DOI: 10.1083/jcb.150.1.1  1
2000 Merdes A, Heald R, Samejima K, Earnshaw WC, Cleveland DW. Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. The Journal of Cell Biology. 149: 851-62. PMID 10811826 DOI: 10.1083/jcb.149.4.851  1
2000 Williamson TL, Corson LB, Huang L, Burlingame A, Liu J, Bruijn LI, Cleveland DW. Toxicity of ALS-linked SOD1 mutants. Science (New York, N.Y.). 288: 399. PMID 10798964  0.44
1999 Cleveland DW. From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. Neuron. 24: 515-20. PMID 10595505  1
1999 Houseweart MK, Cleveland DW. Cytoskeletal linkers: new MAPs for old destinations. Current Biology : Cb. 9: R864-6. PMID 10574751  1
1999 Kahana JA, Cleveland DW. Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly. The Journal of Cell Biology. 146: 1205-10. PMID 10491385 DOI: 10.1083/jcb.146.6.1205  1
1999 Corson LB, Folmer J, Strain JJ, Culotta VC, Cleveland DW. Oxidative stress and iron are implicated in fragmenting vacuoles of Saccharomyces cerevisiae lacking Cu,Zn-superoxide dismutase. The Journal of Biological Chemistry. 274: 27590-6. PMID 10488097 DOI: 10.1074/jbc.274.39.27590  1
1999 Houseweart MK, Cleveland DW. Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6446-56. PMID 10414973  1
1999 Ratovitski T, Corson LB, Strain J, Wong P, Cleveland DW, Culotta VC, Borchelt DR. Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds. Human Molecular Genetics. 8: 1451-60. PMID 10400992 DOI: 10.1093/hmg/8.8.1451  1
1999 Williamson TL, Cleveland DW. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nature Neuroscience. 2: 50-6. PMID 10195180 DOI: 10.1038/4553  1
1999 Rothstein JD, Dykes-Hoberg M, Corson LB, Becker M, Cleveland DW, Price DL, Culotta VC, Wong PC. The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. Journal of Neurochemistry. 72: 422-9. PMID 9886096 DOI: 10.1046/j.1471-4159.1999.0720422.x  1
1998 Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, Brown RH. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 15763-8. PMID 9861044 DOI: 10.1073/pnas.95.26.15763  1
1998 Rao MV, Houseweart MK, Williamson TL, Crawford TO, Folmer J, Cleveland DW. Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. The Journal of Cell Biology. 143: 171-81. PMID 9763429 DOI: 10.1083/jcb.143.1.171  1
1998 Bruijn LI, Houseweart MK, Kato S, Anderson KL, Anderson SD, Ohama E, Reaume AG, Scott RW, Cleveland DW. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science (New York, N.Y.). 281: 1851-4. PMID 9743498 DOI: 10.1126/science.281.5384.1851  1
1998 Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiology of Disease. 5: 27-35. PMID 9702785 DOI: 10.1006/nbdi.1998.0178  1
1998 Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 95: 9631-6. PMID 9689132  0.52
1998 Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/pnas.95.16.9626  1
1998 Corson LB, Strain JJ, Culotta VC, Cleveland DW. Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants. Proceedings of the National Academy of Sciences of the United States of America. 95: 6361-6. PMID 9600970 DOI: 10.1073/pnas.95.11.6361  1
1998 Houseweart MK, Cleveland DW. Intermediate filaments and their associated proteins: multiple dynamic personalities. Current Opinion in Cell Biology. 10: 93-101. PMID 9484600 DOI: 10.1016/S0955-0674(98)80091-4  1
1998 Eyer J, Cleveland DW, Wong PC, Peterson AC. Pathogenesis of two axonopathies does not require axonal neurofilaments. Nature. 391: 584-7. PMID 9468135 DOI: 10.1038/35378  1
1998 Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science (New York, N.Y.). 279: 514-9. PMID 9438837 DOI: 10.1126/science.279.5350.514  1
1998 Merdes A, Cleveland DW. The role of NuMA in the interphase nucleus. Journal of Cell Science. 111: 71-9. PMID 9394013  1
1997 Yao X, Anderson KL, Cleveland DW. The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. The Journal of Cell Biology. 139: 435-47. PMID 9334346 DOI: 10.1083/jcb.139.2.435  1
1997 Merdes A, Cleveland DW. Pathways of spindle pole formation: different mechanisms; conserved components. The Journal of Cell Biology. 138: 953-6. PMID 9281574 DOI: 10.1083/jcb.138.5.953  1
1997 Duesbery NS, Choi T, Brown KD, Wood KW, Resau J, Fukasawa K, Cleveland DW, Vande Woude GF. CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II. Proceedings of the National Academy of Sciences of the United States of America. 94: 9165-70. PMID 9256453 DOI: 10.1073/pnas.94.17.9165  1
1997 Bruijn LI, Beal MF, Becher MW, Schulz JB, Wong PC, Price DL, Cleveland DW. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 94: 7606-11. PMID 9207139 DOI: 10.1073/pnas.94.14.7606  1
1997 Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron. 18: 327-38. PMID 9052802 DOI: 10.1016/S0896-6273(00)80272-X  1
1996 Price DL, Borchelt DR, Wong PC, Pardo CA, Thinakaran G, Lee MK, Cleveland DW, Sisodia SS. Neurodegenerative diseases and model systems. Cold Spring Harbor Symposia On Quantitative Biology. 61: 725-38. PMID 9246498  1
1996 Williamson TL, Marszalek JR, Vechio JD, Bruijn LI, Lee MK, Xu Z, Brown RH, Cleveland DW. Neurofilaments, radial growth of axons, and mechanisms of motor neuron disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 709-23. PMID 9246497  1
1996 Copete MA, Cleveland DB, Orban RE, Chen SY. Squamous carcinoma arising from a dentigerous cyst: report of a case. Compendium of Continuing Education in Dentistry (Jamesburg, N.J. : 1995). 17: 202-4. PMID 9051985  0.6
1996 Bruijn LI, Cleveland DW. Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease. Neuropathology and Applied Neurobiology. 22: 373-87. PMID 8930947  1
1996 Marszalek JR, Williamson TL, Lee MK, Xu Z, Hoffman PN, Becher MW, Crawford TO, Cleveland DW. Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport. The Journal of Cell Biology. 135: 711-24. PMID 8909545 DOI: 10.1083/jcb.135.3.711  1
1996 Merdes A, Ramyar K, Vechio JD, Cleveland DW. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 87: 447-58. PMID 8898198 DOI: 10.1016/S0092-8674(00)81365-3  1
1996 Vechio JD, Bruijn LI, Xu Z, Brown RH, Cleveland DW. Sequence variants in human neurofilament proteins: absence of linkage to familial amyotrophic lateral sclerosis. Annals of Neurology. 40: 603-10. PMID 8871580 DOI: 10.1002/ana.410400410  0.56
1996 Price DL, Koliatsos VE, Wong PC, Pardo CA, Borchelt DR, Lee MK, Cleveland DW, Griffin JW, Hoffman PN, Cork LC, Sisodia SS. Motor neuron disease and model systems: aetiologies, mechanisms and therapies. Ciba Foundation Symposium. 196: 3-13; discussion 13-. PMID 8866125  1
1996 Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 47: S54-61; discussion S. PMID 8858052  1
1996 Lee MK, Cleveland DW. Neuronal intermediate filaments. Annual Review of Neuroscience. 19: 187-217. PMID 8833441 DOI: 10.1146/annurev.ne.19.030196.001155  1
1996 Yang Y, Dowling J, Yu QC, Kouklis P, Cleveland DW, Fuchs E. An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell. 86: 655-65. PMID 8752219 DOI: 10.1016/S0092-8674(00)80138-5  1
1996 Brown KD, Wood KW, Cleveland DW. The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. Journal of Cell Science. 109: 961-9. PMID 8743943  1
1996 DeSalvo MS, Copete MA, Riesenberger RE, Cleveland DB, Chen SY. Segmental odontomaxillary dysplasia (hemimaxillofacial dysplasia): case report. Pediatric Dentistry. 18: 154-6. PMID 8710720  0.6
1996 Dong DL, Xu ZS, Hart GW, Cleveland DW. Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H. The Journal of Biological Chemistry. 271: 20845-52. PMID 8702840  0.64
1996 Xu Z, Marszalek JR, Lee MK, Wong PC, Folmer J, Crawford TO, Hsieh ST, Griffin JW, Cleveland DW. Subunit composition of neurofilaments specifies axonal diameter. The Journal of Cell Biology. 133: 1061-9. PMID 8655579 DOI: 10.1083/jcb.133.5.1061  1
1996 Cleveland DW. Neuronal growth and death: order and disorder in the axoplasm. Cell. 84: 663-6. PMID 8625404 DOI: 10.1016/S0092-8674(00)81044-2  1
1995 Pardo CA, Xu Z, Borchelt DR, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proceedings of the National Academy of Sciences of the United States of America. 92: 954-8. PMID 7862672 DOI: 10.1073/pnas.92.4.954  1
1995 Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of Biological Chemistry. 270: 3234-8. PMID 7852409 DOI: 10.1074/jbc.270.7.3234  1
1995 Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14: 1105-16. PMID 7605627 DOI: 10.1016/0896-6273(95)90259-7  1
1995 Wong PC, Marszalek J, Crawford TO, Xu Z, Hsieh ST, Griffin JW, Cleveland DW. Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. The Journal of Cell Biology. 130: 1413-22. PMID 7559762 DOI: 10.1083/jcb.130.6.1413  1
1995 Cleveland DW, Laing N, Hurse PV, Brown RH. Toxic mutants in Charcot's sclerosis. Nature. 378: 342-3. PMID 7477368 DOI: 10.1038/378342a0  0.56
1994 Price DL, Cleveland DW, Koliatsos VE. Motor neurone disease and animal models. Neurobiology of Disease. 1: 3-11. PMID 9216981 DOI: 10.1006/nbdi.1994.0002  1
1994 Brown KD, Coulson RM, Yen TJ, Cleveland DW. Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. The Journal of Cell Biology. 125: 1303-12. PMID 8207059  1
1994 Cleveland DB, Chen SY, Allen CM, Ahing SI, Svirsky JA. Adult rhabdomyoma. A light microscopic, ultrastructural, virologic, and immunologic analysis. Oral Surgery, Oral Medicine, and Oral Pathology. 77: 147-53. PMID 8139832  0.6
1994 Katz DA, Theodorakis NG, Cleveland DW, Lindsten T, Thompson CB. AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm. Nucleic Acids Research. 22: 238-46. PMID 8121809  1
1994 Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8292-6. PMID 8058797 DOI: 10.1073/pnas.91.17.8292  1
1994 Hsieh ST, Kidd GJ, Crawford TO, Xu Z, Lin WM, Trapp BD, Cleveland DW, Griffin JW. Regional modulation of neurofilament organization by myelination in normal axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6392-401. PMID 7965044  0.44
1994 Gill SR, Cleveland DW, Schroer TA. Characterization of DLC-A and DLC-B, two families of cytoplasmic dynein light chain subunits. Molecular Biology of the Cell. 5: 645-54. PMID 7949421  1
1994 Lee MK, Marszalek JR, Cleveland DW. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron. 13: 975-88. PMID 7946341 DOI: 10.1016/0896-6273(94)90263-1  1
1994 Compton DA, Cleveland DW. NuMA, a nuclear protein involved in mitosis and nuclear reformation. Current Opinion in Cell Biology. 6: 343-6. PMID 7917323 DOI: 10.1016/0955-0674(94)90024-8  1
1994 Xu Z, Dong DL, Cleveland DW. Neuronal intermediate filaments: new progress on an old subject. Current Opinion in Neurobiology. 4: 655-61. PMID 7849521  0.44
1994 Lee MK, Cleveland DW. Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease. Current Opinion in Cell Biology. 6: 34-40. PMID 7513179 DOI: 10.1016/0955-0674(94)90113-9  1
1993 Lee MK, Xu Z, Wong PC, Cleveland DW. Neurofilaments are obligate heteropolymers in vivo. The Journal of Cell Biology. 122: 1337-50. PMID 8376466  0.64
1993 Heins S, Wong PC, Müller S, Goldie K, Cleveland DW, Aebi U. The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation. The Journal of Cell Biology. 123: 1517-33. PMID 8253847  0.64
1990 Sisodia SS, Gay DA, Cleveland DW. In vivo discrimination among beta-tubulin isotypes: selective degradation of a type IV beta-tubulin isotype following overexpression in cultured animal cells. The New Biologist. 2: 66-76. PMID 2078553  0.64
1989 Gay DA, Sisodia SS, Cleveland DW. Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation. Proceedings of the National Academy of Sciences of the United States of America. 86: 5763-7. PMID 2762294  0.64
1987 Sisodia SS, Sollner-Webb B, Cleveland DW. Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylation. Molecular and Cellular Biology. 7: 3602-12. PMID 3683396  1
1987 Gabriel A, Sisodia SS, Cleveland DW. Evidence of discontinuous transcription in the trypanosomatid Crithidia fasciculata. The Journal of Biological Chemistry. 262: 16192-9. PMID 3680249  0.64
1987 Sisodia SS, Cleveland DW, Sollner-Webb B. A combination of RNase H and S1 nuclease circumvents an artefact inherent to conventional S1 analysis of RNA splicing. Nucleic Acids Research. 15: 1995-2011. PMID 3031584 DOI: 10.1093/nar/15.5.1995  1
1981 Valenzuela P, Quiroga M, Zaldivar J, Rutter WJ, Kirschner MW, Cleveland DW. Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs. Nature. 289: 650-5. PMID 7464932 DOI: 10.1038/289650a0  1
1981 Cleveland DW, Hughes SH, Stubblefield E, Kirschner MW, Varmus HE. Multiple alpha and beta tubulin genes represent unlinked and dispersed gene families. The Journal of Biological Chemistry. 256: 3130-4. PMID 6259149  0.88
1981 Cleveland DW, Lopata MA, Sherline P, Kirschner MW. Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell. 25: 537-46. PMID 6116546  0.88
1980 Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW. Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell. 20: 95-105. PMID 6893015 DOI: 10.1016/0092-8674(80)90238-X  1
1980 Sánchez F, Natzle JE, Cleveland DW, Kirschner MW, McCarthy BJ. A dispersed multigene family encoding tubulin in Drosophila melanogaster. Cell. 22: 845-54. PMID 6780200 DOI: 10.1016/0092-8674(80)90561-9  1
1979 Cleveland DW, Spiegelman BM, Kirschner MW. Conservation of microtubule associated proteins. Isolation and characterization of tau and the high molecular weight microtubule associated protein from chicken brain and from mouse fibroblasts and comparison to the corresponding mammalian brain proteins. The Journal of Biological Chemistry. 254: 12670-8. PMID 227904  0.88
1978 Cleveland DW, Kirschner MW, Cowan NJ. Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products. Cell. 15: 1021-31. PMID 728983 DOI: 10.1016/0092-8674(78)90286-6  1
1978 Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence. The Journal of Cell Biology. 76: 781-6. PMID 344329  0.88
1977 Cleveland DW, Hwo SY, Kirschner MW. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. Journal of Molecular Biology. 116: 207-25. PMID 599557  0.88
1977 Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. Immunoflourescent staining of cytoplasmic and spindle microtubules in mouse fibroblasts with antibody to tau protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 2437-40. PMID 329285  0.88
1977 Cleveland DW, Fischer SG, Kirschner MW, Laemmli UK. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. The Journal of Biological Chemistry. 252: 1102-6. PMID 320200  0.88
1977 Cleveland DW, Hwo SY, Kirschner MW. Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. Journal of Molecular Biology. 116: 227-47. PMID 146092  0.88
1976 Witman GB, Cleveland DW, Weingarten MD, Kirschner MW. Tubulin requires tau for growth onto microtubule initiating sites. Proceedings of the National Academy of Sciences of the United States of America. 73: 4070-4. PMID 1069293  0.88
Show low-probability matches.