Dana Philpott - Publications

Affiliations: 
Immunology University of Toronto, Toronto, ON, Canada 
Area:
NOD2, IBD, microbiota

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Foerster EG, K L Tsang D, Goyal S, Robertson SJ, Robert LM, Maughan H, Streutker CJ, Girardin SE, Philpott DJ. ATG16L1 protects from IFN-γ-induced cell death in the small intestinal crypt. Mucosal Immunology. PMID 36792009 DOI: 10.1016/j.mucimm.2023.02.001  0.694
2022 Kim JE, Li B, Fei L, Horne R, Lee D, Loe AK, Miyake H, Ayar E, Kim DK, Surette MG, Philpott DJ, Sherman P, Guo G, Pierro A, Kim TH. Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development. Immunity. PMID 36473468 DOI: 10.1016/j.immuni.2022.11.003  0.463
2022 Killackey SA, Bi Y, Philpott DJ, Arnoult D, Girardin SE. Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1. Autophagy. 1-3. PMID 36170592 DOI: 10.1080/15548627.2022.2129763  0.642
2022 Boroumand P, Prescott DC, Mukherjee T, Bilan PJ, Wong M, Shen J, Tattoli I, Zhou Y, Li A, Sivasubramaniyam T, Shi N, Zhu LY, Liu Z, Robbins C, Philpott DJ, et al. Bone marrow adipocytes drive the development of tissue invasive Ly6C monocytes during obesity. Elife. 11. PMID 36125130 DOI: 10.7554/eLife.65553  0.646
2022 Cabral-Fernandes L, Goyal S, Farahvash A, Tsalikis J, Philpott DJ, Girardin SE. Invading Bacterial Pathogens Activate Transcription Factor EB in Epithelial Cells through the Amino Acid Starvation Pathway of mTORC1 Inhibition. Molecular and Cellular Biology. e0024122. PMID 36005752 DOI: 10.1128/mcb.00241-22  0.726
2022 Tsang DKL, Wang RJ, De Sa O, Ayyaz A, Foerster EG, Bayer G, Goyal S, Trcka D, Ghoshal B, Wrana JL, Girardin SE, Philpott DJ. A single cell survey of the microbial impacts on the mouse small intestinal epithelium. Gut Microbes. 14: 2108281. PMID 35939622 DOI: 10.1080/19490976.2022.2108281  0.712
2022 Lin Q, Kuypers M, Liu Z, Copeland JK, Chan D, Robertson SJ, Kontogiannis J, Guttman DS, Banks EK, Philpott DJ, Mallevaey T. Invariant natural killer T cells minimally influence gut microbiota composition in mice. Gut Microbes. 14: 2104087. PMID 35912530 DOI: 10.1080/19490976.2022.2104087  0.302
2022 Killackey SA, Bi Y, Soares F, Hammi I, Winsor NJ, Abdul-Sater AA, Philpott DJ, Arnoult D, Girardin SE. Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1. Molecular Cell. PMID 35752171 DOI: 10.1016/j.molcel.2022.06.004  0.65
2022 Bruce JK, Burns GL, Sinn Soh W, Nair PM, Sherwin S, Fan K, Dowling LR, Goggins BJ, Koloski N, Potter M, Bollipo S, Foster R, Gan LT, Veysey M, Philpott DJ, et al. Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia. Brain, Behavior, and Immunity. PMID 35093492 DOI: 10.1016/j.bbi.2022.01.019  0.682
2021 Nathan NN, Philpott DJ, Girardin SE. The Intestinal Microbiota: from health to disease, and back. Microbes and Infection. 104849. PMID 34146716 DOI: 10.1016/j.micinf.2021.104849  0.647
2021 Foerster EG, Mukherjee T, Cabral-Fernandes L, Rocha JDB, Girardin SE, Philpott DJ. How autophagy controls the intestinal epithelial barrier. Autophagy. 1-18. PMID 33906557 DOI: 10.1080/15548627.2021.1909406  0.7
2021 Maisonneuve C, Tsang DKL, Foerster EG, Robert LM, Mukherjee T, Prescott D, Tattoli I, Lemire P, Winer DA, Winer S, Streutker CJ, Geddes K, Cadwell K, Ferrero RL, Martin A, ... ... Philpott DJ, et al. Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells. Cell Reports. 34: 108677. PMID 33503439 DOI: 10.1016/j.celrep.2020.108677  0.668
2020 Mukherjee T, Ramaglia V, Abdel-Nour M, Bianchi AA, Tsalikis J, Chau HN, Kalia SK, Kalia LV, Chen JJ, Arnoult D, Gommerman JL, Philpott DJ, Girardin SE. The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates. The Journal of Biological Chemistry. PMID 33168630 DOI: 10.1074/jbc.RA120.014415  0.662
2020 Killackey SA, Philpott DJ, Girardin SE. Mitophagy pathways in health and disease. The Journal of Cell Biology. 219. PMID 32926082 DOI: 10.1083/Jcb.202004029  0.651
2020 Girardin SE, Cuziol C, Philpott DJ, Arnoult D. The eIF2α kinase HRI in innate immunity, proteostasis, and mitochondrial stress. The Febs Journal. PMID 32892501 DOI: 10.1111/Febs.15553  0.678
2020 Winsor NJ, Killackey SA, Philpott DJ, Girardin SE. An optimized procedure for quantitative analysis of mitophagy with the mtKeima system using flow cytometry. Biotechniques. PMID 32806949 DOI: 10.2144/Btn-2020-0071  0.614
2020 Prescott D, Maisonneuve C, Yadav J, Rubino SJ, Girardin SE, Philpott DJ. NOD2 modulates immune tolerance via the GM-CSF-dependent generation of CD103 dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32350141 DOI: 10.1073/Pnas.1912866117  0.707
2020 Chonwerawong M, Ferrand J, Chaudhry HM, Higgins C, Tran LS, Lim SS, Walker MM, Bhathal PS, Dev A, Moore GT, Sievert W, Jenkins BJ, D'Elios MM, Philpott DJ, Kufer TA, et al. Innate Immune Molecule NLRC5 Protects Mice From Helicobacter-induced Formation of Gastric Lymphoid Tissue. Gastroenterology. PMID 32169428 DOI: 10.1053/j.gastro.2020.03.009  0.322
2019 Abdel-Nour M, Carneiro LAM, Downey J, Tsalikis J, Outlioua A, Prescott D, Da Costa LS, Hovingh ES, Farahvash A, Gaudet RG, Molinaro R, van Dalen R, Lau CCY, Azimi FC, Escalante NK, ... ... Philpott DJ, et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science (New York, N.Y.). 365. PMID 31273097 DOI: 10.1126/Science.Aaw4144  0.703
2019 Winsor N, Krustev C, Bruce J, Philpott DJ, Girardin SE. Canonical and non-canonical inflammasomes in intestinal epithelial cells. Cellular Microbiology. e13079. PMID 31265745 DOI: 10.1111/Cmi.13079  0.717
2019 Robertson SJ, Lemire P, Maughan H, Goethel A, Turpin W, Bedrani L, Guttman DS, Croitoru K, Girardin SE, Philpott DJ. Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models. Cell Reports. 27: 1910-1919.e2. PMID 31067473 DOI: 10.1016/J.Celrep.2019.04.023  0.639
2019 Molinaro R, Mukherjee T, Flick R, Philpott DJ, Girardin SE. Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress. The Journal of Biological Chemistry. PMID 30996003 DOI: 10.1074/Jbc.Ra119.007997  0.695
2019 Tsalikis J, Abdel-Nour M, Farahvash A, Sorbara MT, Poon S, Philpott DJ, Girardin SE. Isoginkgetin, a natural biflavonoid proteasome inhibitor, sensitizes cancer cells to apoptosis via disruption of lysosomal homeostasis and impaired protein clearance. Molecular and Cellular Biology. PMID 30910794 DOI: 10.1128/Mcb.00489-18  0.672
2019 Sun T, Ferrero RL, Girardin SE, Gommerman JL, Philpott DJ. NLRC5 deficiency has a moderate impact on immunodominant CD8 T cell responses during rotavirus infection of adult mice. Immunology and Cell Biology. PMID 30768806 DOI: 10.1111/Imcb.12244  0.7
2018 Mukherjee T, Hovingh ES, Foerster EG, Abdel-Nour M, Philpott DJ, Girardin SE. NOD1 and NOD2 in inflammation, immunity and disease. Archives of Biochemistry and Biophysics. PMID 30578751 DOI: 10.1016/J.Abb.2018.12.022  0.741
2018 Platnich JM, Chung H, Lau A, Sandall CF, Bondzi-Simpson A, Chen HM, Komada T, Trotman-Grant AC, Brandelli JR, Chun J, Beck PL, Philpott DJ, Girardin SE, Ho M, Johnson RP, et al. Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome. Cell Reports. 25: 1525-1536.e7. PMID 30404007 DOI: 10.1016/J.Celrep.2018.09.071  0.668
2018 Robertson SJ, Goethel A, Girardin SE, Philpott DJ. Innate Immune Influences on the Gut Microbiome: Lessons from Mouse Models. Trends in Immunology. PMID 30377046 DOI: 10.1016/J.It.2018.10.004  0.711
2018 Killackey SA, Rahman MA, Soares F, Zhang AB, Abdel-Nour M, Philpott DJ, Girardin SE. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Molecular and Cellular Biochemistry. PMID 30191480 DOI: 10.1007/S11010-018-3444-3  0.678
2018 Goethel A, Croitoru K, Philpott DJ. The interplay between microbes and the immune response in inflammatory bowel disease. The Journal of Physiology. 596: 3869-3882. PMID 29806140 DOI: 10.1113/JP275396  0.338
2018 Sorbara MT, Foerster EG, Tsalikis J, Abdel-Nour M, Mangiapane J, Sirluck-Schroeder I, Tattoli I, van Dalen R, Isenman DE, Rohde JR, Girardin SE, Philpott DJ. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host & Microbe. 23: 644-652.e5. PMID 29746835 DOI: 10.1016/J.Chom.2018.04.008  0.684
2018 Costford SR, Tattoli I, Duan FT, Volchuk A, Klip A, Philpott DJ, Woo M, Girardin SE. Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet-Induced Hyperglycemia. Journal of the Endocrine Society. 2: 336-347. PMID 29577109 DOI: 10.1210/Js.2017-00360  0.646
2018 Lopes F, Keita ÅV, Saxena A, Reyes JL, Mancini N, Rajabi AA, Wang A, Baggio C, Dicay M, van Dalen R, Ahn Y, Carneiro M, Peters N, Rho JM, MacNaughton W, ... ... Philpott DJ, et al. ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction. The Journal of Biological Chemistry. PMID 29317503 DOI: 10.1074/Jbc.Ra117.000809  0.675
2017 Lemire P, Robertson SJ, Maughan H, Tattoli I, Streutker CJ, Platnich JM, Muruve DA, Philpott DJ, Girardin SE. The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition. Cell Reports. 21: 3653-3661. PMID 29281815 DOI: 10.1016/J.Celrep.2017.12.026  0.693
2017 Chan KL, Tam TH, Boroumand P, Prescott D, Costford SR, Escalante NK, Fine N, Tu Y, Robertson SJ, Prabaharan D, Liu Z, Bilan PJ, Salter MW, Glogauer M, Girardin SE, ... Philpott DJ, et al. Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance. Cell Reports. 18: 2415-2426. PMID 28273456 DOI: 10.1016/J.Celrep.2017.02.027  0.681
2016 Escalante NK, Lemire P, Cruz Tleugabulova M, Prescott D, Mortha A, Streutker CJ, Girardin SE, Philpott DJ, Mallevaey T. The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility. The Journal of Experimental Medicine. PMID 27836928 DOI: 10.1084/Jem.20161776  0.72
2016 Selvanantham T, Lin Q, Guo CX, Surendra A, Fieve S, Escalante NK, Guttman DS, Streutker CJ, Robertson SJ, Philpott DJ, Mallevaey T. NKT Cell-Deficient Mice Harbor an Altered Microbiota that Fuels Intestinal Inflammation during Chemically Induced Colitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27799307 DOI: 10.4049/Jimmunol.1601410  0.353
2016 Tsalikis J, Pan Q, Tattoli I, Maisonneuve C, Blencowe BJ, Philpott DJ, Girardin SE. The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress. Bmc Genomics. 17: 680. PMID 27561422 DOI: 10.1186/S12864-016-2999-1  0.664
2016 Zanello G, Goethel A, Rouquier S, Prescott D, Robertson SJ, Maisonneuve C, Streutker C, Philpott DJ, Croitoru K. The Cytosolic Microbial Receptor Nod2 Regulates Small Intestinal Crypt Damage and Epithelial Regeneration following T Cell-Induced Enteropathy. Journal of Immunology (Baltimore, Md. : 1950). PMID 27206769 DOI: 10.4049/jimmunol.1600185  0.302
2016 Robertson SJ, Geddes K, Maisonneuve C, Streutker CJ, Philpott DJ. Resilience of the intestinal microbiota following pathogenic bacterial infection is independent of innate immunity mediated by NOD1 or NOD2. Microbes and Infection / Institut Pasteur. PMID 27083475 DOI: 10.1016/j.micinf.2016.03.014  0.369
2016 Tattoli I, Killackey SA, Foerster EG, Molinaro R, Maisonneuve C, Rahman MA, Winer S, Winer DA, Streutker CJ, Philpott DJ, Girardin SE. NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation. Cell Reports. PMID 26971996 DOI: 10.1016/J.Celrep.2016.02.065  0.699
2015 Wang H, Kim JJ, Denou E, Gallagher A, Thornton DJ, Shajib S, Xia L, Schertzer JD, Grencis RK, Philpott DJ, Khan WI. A new role of Nod proteins in regulation of intestinal goblet cell response in the context of innate host defense in an enteric parasite infection. Infection and Immunity. PMID 26527214 DOI: 10.1128/IAI.01187-15  0.353
2015 Carneiro LA, Fritz JÖ, Kufer TA, Travassos LH, Benko S, Philpott DJ. NLRs: Nucleotide-Binding Domain and Leucine-Rich-Repeat-Containing Proteins. Ecosal Plus. 3. PMID 26443757 DOI: 10.1128/ecosalplus.8.8.3  0.384
2015 Tsalikis J, Tattoli I, Ling A, Sorbara MT, Croitoru DO, Philpott DJ, Girardin SE. Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction. The Journal of Biological Chemistry. 290: 20904-18. PMID 26134566 DOI: 10.1074/Jbc.M115.659466  0.693
2015 Luck H, Tsai S, Chung J, Clemente-Casares X, Ghazarian M, Revelo XS, Lei H, Luk CT, Shi SY, Surendra A, Copeland JK, Ahn J, Prescott D, Rasmussen BA, Chng MH, ... ... Philpott DJ, et al. Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. Cell Metabolism. 21: 527-42. PMID 25863246 DOI: 10.1016/J.Cmet.2015.03.001  0.695
2015 Motta V, Soares F, Sun T, Philpott DJ. NOD-like receptors: versatile cytosolic sentinels. Physiological Reviews. 95: 149-78. PMID 25540141 DOI: 10.1152/Physrev.00009.2014  0.307
2014 Tattoli I, Sorbara MT, Philpott DJ, Girardin SE. Stalling autophagy: a new function for Listeria phospholipases. Microbial Cell (Graz, Austria). 1: 48-50. PMID 28357210 DOI: 10.15698/mic2014.01.124  0.695
2014 Claes AK, Steck N, Schultz D, Zähringer U, Lipinski S, Rosenstiel P, Geddes K, Philpott DJ, Heine H, Grassl GA. Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice. Plos One. 9: e113645. PMID 25423082 DOI: 10.1371/journal.pone.0113645  0.363
2014 Belcheva A, Irrazabal T, Robertson SJ, Streutker C, Maughan H, Rubino S, Moriyama EH, Copeland JK, Kumar S, Green B, Geddes K, Pezo RC, Navarre WW, Milosevic M, Wilson BC, ... ... Philpott DJ, et al. Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells. Cell. 158: 288-99. PMID 25036629 DOI: 10.1016/J.Cell.2014.04.051  0.69
2014 Soares F, Tattoli I, Rahman MA, Robertson SJ, Belcheva A, Liu D, Streutker C, Winer S, Winer DA, Martin A, Philpott DJ, Arnoult D, Girardin SE. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. The Journal of Biological Chemistry. 289: 19317-30. PMID 24867956 DOI: 10.1074/Jbc.M114.550111  0.683
2014 Irrazábal T, Belcheva A, Girardin SE, Martin A, Philpott DJ. The multifaceted role of the intestinal microbiota in colon cancer. Molecular Cell. 54: 309-20. PMID 24766895 DOI: 10.1016/J.Molcel.2014.03.039  0.648
2014 Irving AT, Mimuro H, Kufer TA, Lo C, Wheeler R, Turner LJ, Thomas BJ, Malosse C, Gantier MP, Casillas LN, Votta BJ, Bertin J, Boneca IG, Sasakawa C, Philpott DJ, et al. The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling. Cell Host & Microbe. 15: 623-35. PMID 24746552 DOI: 10.1016/j.chom.2014.04.001  0.413
2014 Philpott DJ, Sorbara MT, Robertson SJ, Croitoru K, Girardin SE. NOD proteins: regulators of inflammation in health and disease. Nature Reviews. Immunology. 14: 9-23. PMID 24336102 DOI: 10.1038/Nri3565  0.747
2013 Sorbara MT, Ellison LK, Ramjeet M, Travassos LH, Jones NL, Girardin SE, Philpott DJ. The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner. Immunity. 39: 858-73. PMID 24238340 DOI: 10.1016/J.Immuni.2013.10.013  0.709
2013 Prescott D, Lee J, Philpott DJ. An epithelial armamentarium to sense the microbiota. Seminars in Immunology. 25: 323-33. PMID 24169517 DOI: 10.1016/j.smim.2013.09.007  0.334
2013 Selvanantham T, Escalante NK, Cruz Tleugabulova M, Fiévé S, Girardin SE, Philpott DJ, Mallevaey T. Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 5646-54. PMID 24163408 DOI: 10.4049/Jimmunol.1301412  0.734
2013 Tattoli I, Sorbara MT, Yang C, Tooze SA, Philpott DJ, Girardin SE. Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. The Embo Journal. 32: 3066-78. PMID 24162724 DOI: 10.1038/Emboj.2013.234  0.714
2013 Rubino SJ, Geddes K, Magalhaes JG, Streutker C, Philpott DJ, Girardin SE. Constitutive induction of intestinal Tc17 cells in the absence of hematopoietic cell-specific MHC class II expression. European Journal of Immunology. 43: 2896-906. PMID 23881368 DOI: 10.1002/Eji.201243028  0.685
2013 Tsalikis J, Croitoru DO, Philpott DJ, Girardin SE. Nutrient sensing and metabolic stress pathways in innate immunity. Cellular Microbiology. 15: 1632-41. PMID 23834352 DOI: 10.1111/Cmi.12165  0.708
2013 Zarantonelli ML, Skoczynska A, Antignac A, El Ghachi M, Deghmane AE, Szatanik M, Mulet C, Werts C, Peduto L, d'Andon MF, Thouron F, Nato F, Lebourhis L, Philpott DJ, Girardin SE, et al. Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis. Cell Host & Microbe. 13: 735-45. PMID 23768497 DOI: 10.1016/J.Chom.2013.04.016  0.703
2013 Robertson SJ, Zhou JY, Geddes K, Rubino SJ, Cho JH, Girardin SE, Philpott DJ. Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis. Gut Microbes. 4: 222-31. PMID 23549220 DOI: 10.4161/Gmic.24373  0.717
2013 Lin GH, Wortzman ME, Girardin SE, Philpott DJ, Watts TH. T cell intrinsic NOD2 is dispensable for CD8 T cell immunity. Plos One. 8: e56014. PMID 23405246 DOI: 10.1371/Journal.Pone.0056014  0.679
2013 Tourneur E, Ben Mkaddem S, Chassin C, Bens M, Goujon JM, Charles N, Pellefigues C, Aloulou M, Hertig A, Monteiro RC, Girardin SE, Philpott DJ, Rondeau E, Elbim C, Werts C, et al. Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients. Plos Pathogens. 9: e1003152. PMID 23382681 DOI: 10.1371/Journal.Ppat.1003152  0.679
2013 Rubino SJ, Magalhaes JG, Philpott D, Bahr GM, Blanot D, Girardin SE. Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity. Innate Immunity. 19: 493-503. PMID 23339926 DOI: 10.1177/1753425912471691  0.716
2013 Soares F, Tattoli I, Wortzman ME, Arnoult D, Philpott DJ, Girardin SE. NLRX1 does not inhibit MAVS-dependent antiviral signalling. Innate Immunity. 19: 438-48. PMID 23212541 DOI: 10.1177/1753425912467383  0.695
2013 Van Limbergen J, Kabakchiev B, Stempak JM, Schumm P, Xu W, Henderson P, Girardin S, Griffiths AM, Philpott D, Silverberg M. Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility. Gut. 62: 331-3. PMID 22833393 DOI: 10.1136/Gutjnl-2012-303165  0.673
2012 Tattoli I, Philpott DJ, Girardin SE. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biology Open. 1: 1215-25. PMID 23259056 DOI: 10.1242/Bio.20122840  0.714
2012 Tattoli I, Sorbara MT, Philpott DJ, Girardin SE. Bacterial autophagy: the trigger, the target and the timing. Autophagy. 8: 1848-50. PMID 22932645 DOI: 10.4161/Auto.21863  0.714
2012 Ling A, Soares F, Croitoru DO, Tattoli I, Carneiro LA, Boniotto M, Benko S, Philpott DJ, Girardin SE. Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3. The Journal of Biological Chemistry. 287: 28705-16. PMID 22718770 DOI: 10.1074/Jbc.M111.333146  0.681
2012 Tattoli I, Sorbara MT, Vuckovic D, Ling A, Soares F, Carneiro LA, Yang C, Emili A, Philpott DJ, Girardin SE. Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host & Microbe. 11: 563-75. PMID 22704617 DOI: 10.1016/J.Chom.2012.04.012  0.727
2012 Rubino SJ, Selvanantham T, Girardin SE, Philpott DJ. Nod-like receptors in the control of intestinal inflammation. Current Opinion in Immunology. 24: 398-404. PMID 22677577 DOI: 10.1016/J.Coi.2012.04.010  0.704
2012 Lee J, Geddes K, Streutker C, Philpott DJ, Girardin SE. Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo. Infection and Immunity. 80: 2645-54. PMID 22615249 DOI: 10.1128/Iai.00168-12  0.743
2012 Lee BH, Hwang DM, Palaniyar N, Grinstein S, Philpott DJ, Hu J. Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection. Plos One. 7: e35812. PMID 22558229 DOI: 10.1371/Journal.Pone.0035812  0.351
2012 Hancock RE, Nijnik A, Philpott DJ. Modulating immunity as a therapy for bacterial infections. Nature Reviews. Microbiology. 10: 243-54. PMID 22421877 DOI: 10.1038/nrmicro2745  0.313
2012 Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, ... ... Philpott DJ, et al. Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology. 142: 1160-71. PMID 22333951 DOI: 10.1053/J.Gastro.2012.01.043  0.647
2012 Lacroix-Lamandé S, d'Andon MF, Michel E, Ratet G, Philpott DJ, Girardin SE, Boneca IG, Vandewalle A, Werts C. Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 188: 2805-14. PMID 22323544 DOI: 10.4049/Jimmunol.1101987  0.671
2012 Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, et al. Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature. 481: 199-203. PMID 22158124 DOI: 10.1038/Nature10698  0.691
2011 Sorbara MT, Philpott DJ. Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis. Immunological Reviews. 243: 40-60. PMID 21884166 DOI: 10.1111/j.1600-065X.2011.01047.x  0.36
2011 Magalhaes JG, Rubino SJ, Travassos LH, Le Bourhis L, Duan W, Sellge G, Geddes K, Geddes K, Reardon C, Lechmann M, Carneiro LA, Selvanantham T, Fritz JH, Taylor BC, Artis D, ... ... Philpott DJ, et al. Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proceedings of the National Academy of Sciences of the United States of America. 108: 14896-901. PMID 21856952 DOI: 10.1073/Pnas.1015063108  0.707
2011 Gareau MG, Ho NK, Brenner D, Sousa AJ, Lebourhis L, Mak TW, Girardin SE, Philpott DJ, Sherman PM. Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha. Microbiology (Reading, England). 157: 2963-73. PMID 21798984 DOI: 10.1099/Mic.0.051094-0  0.789
2011 Geddes K, Rubino SJ, Magalhaes JG, Streutker C, Le Bourhis L, Cho JH, Robertson SJ, Kim CJ, Kaul R, Philpott DJ, Girardin SE. Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nature Medicine. 17: 837-44. PMID 21666695 DOI: 10.1038/Nm.2391  0.697
2011 Werts C, Rubino S, Ling A, Girardin SE, Philpott DJ. Nod-like receptors in intestinal homeostasis, inflammation, and cancer. Journal of Leukocyte Biology. 90: 471-82. PMID 21653239 DOI: 10.1189/Jlb.0411183  0.705
2011 Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, ... Philpott DJ, et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 795-808. PMID 21552986 DOI: 10.1007/S00702-011-0653-2  0.702
2011 Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, Girardin SE. Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands. European Journal of Immunology. 41: 1445-55. PMID 21469090 DOI: 10.1002/Eji.201040827  0.736
2011 Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong DJ, Philpott DJ, van der Meer JW, Girardin SE, Joosten LA, Netea MG. Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut. 60: 1229-35. PMID 21406388 DOI: 10.1136/Gut.2010.228908  0.674
2011 Magalhaes JG, Sorbara MT, Girardin SE, Philpott DJ. What is new with Nods? Current Opinion in Immunology. 23: 29-34. PMID 21190821 DOI: 10.1016/J.Coi.2010.12.003  0.697
2011 Gareau MG, Wine E, Rodrigues DM, Cho JH, Whary MT, Philpott DJ, Macqueen G, Sherman PM. Bacterial infection causes stress-induced memory dysfunction in mice. Gut. 60: 307-17. PMID 20966022 DOI: 10.1136/Gut.2009.202515  0.445
2010 Ramjeet M, Hussey S, Philpott DJ, Travassos LH. 'Nodophagy': New crossroads in Crohn disease pathogenesis. Gut Microbes. 1: 307-315. PMID 21327039 DOI: 10.4161/gmic.1.5.13295  0.406
2010 Geddes K, Rubino S, Streutker C, Cho JH, Magalhaes JG, Le Bourhis L, Selvanantham T, Girardin SE, Philpott DJ. Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model. Infection and Immunity. 78: 5107-15. PMID 20921147 DOI: 10.1128/Iai.00759-10  0.718
2010 Benko S, Magalhaes JG, Philpott DJ, Girardin SE. NLRC5 limits the activation of inflammatory pathways. Journal of Immunology (Baltimore, Md. : 1950). 185: 1681-91. PMID 20610642 DOI: 10.4049/Jimmunol.0903900  0.704
2010 Philpott DJ, Girardin SE. Nod-like receptors: sentinels at host membranes. Current Opinion in Immunology. 22: 428-34. PMID 20605429 DOI: 10.1016/J.Coi.2010.04.010  0.69
2010 Travassos LH, Carneiro LA, Girardin S, Philpott DJ. Nod proteins link bacterial sensing and autophagy. Autophagy. 6: 409-11. PMID 20200479 DOI: 10.4161/Auto.6.3.11305  0.728
2010 Philpott DJ, Girardin SE. Gut microbes extend reach to systemic innate immunity. Nature Medicine. 16: 160-1. PMID 20134466 DOI: 10.1038/Nm0210-160  0.7
2010 Dharancy S, Body-Malapel M, Louvet A, Berrebi D, Gantier E, Gosset P, Viala J, Hollebecque A, Moreno C, Philpott DJ, Girardin SE, Sansonetti PJ, Desreumaux P, Mathurin P, Dubuquoy L. Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control. Gastroenterology. 138: 1546-56, 1556.e1-5. PMID 20026116 DOI: 10.1053/J.Gastro.2009.12.008  0.717
2010 Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhães JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nuñez G, Girardin SE, ... Philpott DJ, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nature Immunology. 11: 55-62. PMID 19898471 DOI: 10.1038/Ni.1823  0.712
2010 Kaparakis M, Turnbull L, Carneiro L, Firth S, Coleman HA, Parkington HC, Le Bourhis L, Karrar A, Viala J, Mak J, Hutton ML, Davies JK, Crack PJ, Hertzog PJ, Philpott DJ, et al. Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cellular Microbiology. 12: 372-85. PMID 19888989 DOI: 10.1111/J.1462-5822.2009.01404.X  0.74
2009 Girardin SE, Philpott DJ. Innate immunity: the connection with inflammation and disease. Seminars in Immunology. 21: 173-4. PMID 19699108 DOI: 10.1016/J.Smim.2009.08.001  0.691
2009 Arnoult D, Soares F, Tattoli I, Castanier C, Philpott DJ, Girardin SE. An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. Journal of Cell Science. 122: 3161-8. PMID 19692591 DOI: 10.1242/Jcs.051193  0.641
2009 Le Bourhis L, Magalhaes JG, Selvanantham T, Travassos LH, Geddes K, Fritz JH, Viala J, Tedin K, Girardin SE, Philpott DJ. Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar Typhimurium infection. Infection and Immunity. 77: 4480-6. PMID 19620349 DOI: 10.1128/Iai.01067-09  0.736
2009 Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. The Journal of Biological Chemistry. 284: 23818-29. PMID 19570976 DOI: 10.1074/Jbc.M109.033670  0.683
2009 Finney CA, Lu Z, LeBourhis L, Philpott DJ, Kain KC. Disruption of Nod-like receptors alters inflammatory response to infection but does not confer protection in experimental cerebral malaria. The American Journal of Tropical Medicine and Hygiene. 80: 718-22. PMID 19407112 DOI: 10.4269/Ajtmh.2009.80.718  0.321
2009 Chaouche-Drider N, Kaparakis M, Karrar A, Fernandez MI, Carneiro LA, Viala J, Boneca IG, Moran AP, Philpott DJ, Ferrero RL. A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells. Plos One. 4: e5396. PMID 19401779 DOI: 10.1371/journal.pone.0005396  0.358
2009 Philpott DJ, Girardin SE. Crohn's disease-associated Nod2 mutants reduce IL10 transcription. Nature Immunology. 10: 455-7. PMID 19381138 DOI: 10.1038/Ni0509-455  0.665
2009 Carneiro LA, Travassos LH, Soares F, Tattoli I, Magalhaes JG, Bozza MT, Plotkowski MC, Sansonetti PJ, Molkentin JD, Philpott DJ, Girardin SE. Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host & Microbe. 5: 123-36. PMID 19218084 DOI: 10.1016/J.Chom.2008.12.011  0.733
2008 Magalhaes JG, Fritz JH, Le Bourhis L, Sellge G, Travassos LH, Selvanantham T, Girardin SE, Gommerman JL, Philpott DJ. Nod2-dependent Th2 polarization of antigen-specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 7925-35. PMID 19017983 DOI: 10.4049/Jimmunol.181.11.7925  0.722
2008 Benko S, Philpott DJ, Girardin SE. The microbial and danger signals that activate Nod-like receptors. Cytokine. 43: 368-73. PMID 18715799 DOI: 10.1016/J.Cyto.2008.07.013  0.73
2008 Tattoli I, Lembo-Fazio L, Nigro G, Carneiro LA, Ferraro E, Rossi G, Martino MC, de Stefano ME, Cecconi F, Girardin SE, Philpott DJ, Bernardini ML. Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells. Microbes and Infection / Institut Pasteur. 10: 1114-23. PMID 18606244 DOI: 10.1016/J.Micinf.2008.06.004  0.683
2008 Joosten LA, Heinhuis B, Abdollahi-Roodsaz S, Ferwerda G, Lebourhis L, Philpott DJ, Nahori MA, Popa C, Morre SA, van der Meer JW, Girardin SE, Netea MG, van den Berg WB. Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis. Proceedings of the National Academy of Sciences of the United States of America. 105: 9017-22. PMID 18574154 DOI: 10.1073/Pnas.0710445105  0.692
2008 Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, ... ... Philpott D, et al. The NLR gene family: a standard nomenclature. Immunity. 28: 285-7. PMID 18341998 DOI: 10.1016/J.Immuni.2008.02.005  0.595
2008 Body-Malapel M, Dharancy S, Berrebi D, Louvet A, Hugot JP, Philpott DJ, Giovannini M, Chareyre F, Pages G, Gantier E, Girardin SE, Garcia I, Hudault S, Conti F, Sansonetti PJ, et al. NOD2: a potential target for regulating liver injury. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 318-27. PMID 18227809 DOI: 10.1038/Labinvest.3700716  0.709
2008 Tattoli I, Carneiro LA, Jéhanno M, Magalhaes JG, Shu Y, Philpott DJ, Arnoult D, Girardin SE. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. Embo Reports. 9: 293-300. PMID 18219313 DOI: 10.1038/Sj.Embor.7401161  0.687
2008 Fritz JH, Le Bourhis L, Magalhaes JG, Philpott DJ. Innate immune recognition at the epithelial barrier drives adaptive immunity: APCs take the back seat Trends in Immunology. 29: 41-49. PMID 18054284 DOI: 10.1016/j.it.2007.10.002  0.32
2008 Nigro G, Fazio LL, Martino MC, Rossi G, Tattoli I, Liparoti V, De Castro C, Molinaro A, Philpott DJ, Bernardini ML. Muramylpeptide shedding modulates cell sensing of Shigella flexneri. Cellular Microbiology. 10: 682-95. PMID 18042252 DOI: 10.1111/j.1462-5822.2007.01075.x  0.379
2008 Kufer TA, Kremmer E, Adam AC, Philpott DJ, Sansonetti PJ. The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cellular Microbiology. 10: 477-86. PMID 17970764 DOI: 10.1111/J.1462-5822.2007.01062.X  0.502
2007 Werts C, le Bourhis L, Liu J, Magalhaes JG, Carneiro LA, Fritz JH, Stockinger S, Balloy V, Chignard M, Decker T, Philpott DJ, Ma X, Girardin SE. Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway. European Journal of Immunology. 37: 2499-508. PMID 17705131 DOI: 10.1002/Eji.200737069  0.747
2007 Kaparakis M, Philpott DJ, Ferrero RL. Mammalian NLR proteins; discriminating foe from friend. Immunology and Cell Biology. 85: 495-502. PMID 17680011 DOI: 10.1038/sj.icb.7100105  0.357
2007 Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity. 26: 445-59. PMID 17433730 DOI: 10.1016/J.Immuni.2007.03.009  0.703
2007 Boneca IG, Dussurget O, Cabanes D, Nahori MA, Sousa S, Lecuit M, Psylinakis E, Bouriotis V, Hugot JP, Giovannini M, Coyle A, Bertin J, Namane A, Rousselle JC, Cayet N, ... ... Philpott DJ, et al. A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proceedings of the National Academy of Sciences of the United States of America. 104: 997-1002. PMID 17215377 DOI: 10.1073/Pnas.0609672104  0.716
2006 Kapetanovic R, Nahori MA, Balloy V, Fitting C, Philpott DJ, Cavaillon JM, Adib-Conquy M. Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages. Infection and Immunity. 75: 830-7. PMID 17118979 DOI: 10.1128/IAI.01199-06  0.331
2006 Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. Nod-like proteins in immunity, inflammation and disease. Nature Immunology. 7: 1250-7. PMID 17110941 DOI: 10.1038/Ni1412  0.727
2006 Kufer TA, Banks DJ, Philpott DJ. Innate immune sensing of microbes by Nod proteins. Annals of the New York Academy of Sciences. 1072: 19-27. PMID 17057187 DOI: 10.1196/annals.1326.020  0.398
2006 Dubourdeau M, Athman R, Balloy V, Huerre M, Chignard M, Philpott DJ, Latgé JP, Ibrahim-Granet O. Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4. Journal of Immunology (Baltimore, Md. : 1950). 177: 3994-4001. PMID 16951362  0.346
2006 Fritz JH, Girardin SE, Philpott DJ. Innate immune defense through RNA interference. Science's Stke : Signal Transduction Knowledge Environment. 2006: pe27. PMID 16772641 DOI: 10.1126/Stke.3392006Pe27  0.71
2006 Welter-Stahl L, Ojcius DM, Viala J, Girardin S, Liu W, Delarbre C, Philpott D, Kelly KA, Darville T. Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cellular Microbiology. 8: 1047-57. PMID 16681844 DOI: 10.1111/J.1462-5822.2006.00686.X  0.34
2006 Girardin SE, Philpott DJ. PGRP-LB minds the fort. Immunity. 24: 363-6. PMID 16618594 DOI: 10.1016/J.Immuni.2006.04.001  0.676
2005 Magalhaes JG, Philpott DJ, Nahori MA, Jéhanno M, Fritz J, Le Bourhis L, Viala J, Hugot JP, Giovannini M, Bertin J, Lepoivre M, Mengin-Lecreulx D, Sansonetti PJ, Girardin SE. Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. Embo Reports. 6: 1201-7. PMID 16211083 DOI: 10.1038/Sj.Embor.7400552  0.733
2005 Girardin SE, Jéhanno M, Mengin-Lecreulx D, Sansonetti PJ, Alzari PM, Philpott DJ. Identification of the critical residues involved in peptidoglycan detection by Nod1. The Journal of Biological Chemistry. 280: 38648-56. PMID 16172124 DOI: 10.1074/Jbc.M509537200  0.738
2005 Travassos LH, Carneiro LA, Girardin SE, Boneca IG, Lemos R, Bozza MT, Domingues RC, Coyle AJ, Bertin J, Philpott DJ, Plotkowski MC. Nod1 participates in the innate immune response to Pseudomonas aeruginosa. The Journal of Biological Chemistry. 280: 36714-8. PMID 16150702 DOI: 10.1074/Jbc.M501649200  0.738
2005 Netea MG, Ferwerda G, de Jong DJ, Werts C, Boneca IG, Jéhanno M, Van Der Meer JW, Mengin-Lecreulx D, Sansonetti PJ, Philpott DJ, Dharancy S, Girardin SE. The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists. The Journal of Biological Chemistry. 280: 35859-67. PMID 16115863 DOI: 10.1074/Jbc.M504924200  0.731
2005 Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. European Journal of Immunology. 35: 2459-70. PMID 16021602 DOI: 10.1002/Eji.200526286  0.701
2005 Fournier B, Philpott DJ. Recognition of Staphylococcus aureus by the innate immune system. Clinical Microbiology Reviews. 18: 521-40. PMID 16020688 DOI: 10.1128/CMR.18.3.521-540.2005  0.378
2005 Athman R, Fernandez MI, Gounon P, Sansonetti P, Louvard D, Philpott D, Robine S. Shigella flexneri infection is dependent on villin in the mouse intestine and in primary cultures of intestinal epithelial cells. Cellular Microbiology. 7: 1109-16. PMID 16008578 DOI: 10.1111/J.1462-5822.2005.00535.X  0.505
2005 Kufer TA, Fritz JH, Philpott DJ. NACHT-LRR proteins (NLRs) in bacterial infection and immunity Trends in Microbiology. 13: 381-388. PMID 15994078 DOI: 10.1016/j.tim.2005.06.004  0.344
2005 Carneiro LA, Travassos LH, Philpott DJ. Innate immune recognition of microbes through Nod1 and Nod2: implications for disease. Microbes and Infection. 6: 609-16. PMID 15158196 DOI: 10.1016/j.micinf.2004.01.012  0.369
2004 Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Mémet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nature Immunology. 5: 1166-74. PMID 15489856 DOI: 10.1038/Ni1131  0.736
2004 Philpott DJ, Girardin SE. The role of Toll-like receptors and Nod proteins in bacterial infection. Molecular Immunology. 41: 1099-108. PMID 15476921 DOI: 10.1016/J.Molimm.2004.06.012  0.736
2004 Travassos LH, Girardin SE, Philpott DJ, Blanot D, Nahori MA, Werts C, Boneca IG. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. Embo Reports. 5: 1000-6. PMID 15359270 DOI: 10.1038/Sj.Embor.7400248  0.704
2004 Viala Ja, Sansonetti P, Philpott DJ. Nods and 'intracellular' innate immunity. Comptes Rendus Biologies. 327: 551-555. PMID 15330254 DOI: 10.1016/J.Crvi.2004.02.010  0.538
2004 Girardin SE, Philpott DJ. Mini-review: the role of peptidoglycan recognition in innate immunity. European Journal of Immunology. 34: 1777-82. PMID 15214025 DOI: 10.1002/Eji.200425095  0.735
2004 Philpott DJ, Viala J. Towards an understanding of the role of NOD2/CARD15 in the pathogenesis of Crohn's disease. Best Practice & Research. Clinical Gastroenterology. 18: 555-68. PMID 15157827 DOI: 10.1016/j.bpg.2003.12.004  0.397
2004 Athman R, Philpott D. Innate immunity via Toll-like receptors and Nod proteins. Current Opinion in Microbiology. 7: 25-32. PMID 15036136 DOI: 10.1016/j.mib.2003.12.013  0.362
2003 Girardin SE, Philpott DJ, Lemaitre B. Sensing microbes by diverse hosts. Workshop on pattern recognition proteins and receptors. Embo Reports. 4: 932-6. PMID 14502224 DOI: 10.1038/Sj.Embor.Embor940  0.728
2003 Chamaillard M, Girardin SE, Viala J, Philpott DJ. Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cellular Microbiology. 5: 581-92. PMID 12925128 DOI: 10.1046/J.1462-5822.2003.00304.X  0.724
2003 Girardin SE, Travassos LH, Hervé M, Blanot D, Boneca IG, Philpott DJ, Sansonetti PJ, Mengin-Lecreulx D. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. The Journal of Biological Chemistry. 278: 41702-8. PMID 12871942 DOI: 10.1074/Jbc.M307198200  0.747
2003 Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jéhanno M, Viala J, Tedin K, Taha MK, Labigne A, Zähringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (New York, N.Y.). 300: 1584-7. PMID 12791997 DOI: 10.1126/Science.1084677  0.742
2003 Chamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard-Lacronique V, Sansonetti PJ, Hugot JP, Thomas G. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America. 100: 3455-60. PMID 12626759 DOI: 10.1073/Pnas.0530276100  0.714
2003 Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. The Journal of Biological Chemistry. 278: 8869-72. PMID 12527755 DOI: 10.1074/Jbc.C200651200  0.734
2002 Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B. Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology. The Embo Journal. 21: 5069-78. PMID 12356723 DOI: 10.1093/Emboj/Cdf522  0.459
2002 Philpott DJ, Belaid D, Troubadour P, Thiberge JM, Tankovic J, Labigne A, Ferrero RL. Reduced activation of inflammatory responses in host cells by mouse-adapted Helicobacter pylory isolates. Cellular Microbiology. 4: 285-96. PMID 12064285 DOI: 10.1046/j.1462-5822.2002.00189.x  0.312
2002 Girardin SE, Sansonetti PJ, Philpott DJ. Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies. Trends in Microbiology. 10: 193-9. PMID 11912027 DOI: 10.1016/S0966-842X(02)02334-X  0.764
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