Heidi Jacobs - Publications

Affiliations: 
Massachusetts General Hospital & Harvard Medical School, Boston, MA, United States 
Area:
Alzheimer's disease, biomarkers, neuroimaging, neuropsychology, neurotransmitters, locus coeruleus, tau, amyloid, MRI

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Engels-Domínguez N, Riphagen JM, Van Egroo M, Koops EA, Smegal LF, Becker JA, Prokopiou PC, Bueichekú E, Kwong KK, Rentz DM, Salat DH, Sperling RA, Johnson KA, Jacobs HIL. Lower Locus Coeruleus Integrity Signals Elevated Entorhinal Tau and Clinical Progression in Asymptomatic Older Individuals. Annals of Neurology. PMID 39007398 DOI: 10.1002/ana.27022  0.805
2024 Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA. Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38988055 DOI: 10.1002/alz.14036  0.63
2024 Boyle R, Townsend DL, Klinger HM, Scanlon CE, Yuan Z, Coughlan GT, Seto M, Shirzadi Z, Yau WW, Jutten RJ, Schneider C, Farrell ME, Hanseeuw BJ, Mormino EC, Yang HS, ... ... Jacobs HIL, et al. Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau, and neurodegeneration. Alzheimer's Research & Therapy. 16: 148. PMID 38961512 DOI: 10.1186/s13195-024-01510-y  0.779
2024 Beckers E, Van Egroo M, Ashton NJ, Blennow K, Vandewalle G, Zetterberg H, Poser BA, Jacobs HIL. Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study. Cerebral Cortex (New York, N.Y. : 1991). 34. PMID 38904081 DOI: 10.1093/cercor/bhae261  0.363
2024 Engels-Domínguez N, Koops EA, Hsieh S, Wiklund EE, Schultz AP, Riphagen JM, Prokopiou PC, Hanseeuw BJ, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's pathology: a cohort study. Alzheimer's Research & Therapy. 16: 129. PMID 38886798 DOI: 10.1186/s13195-024-01500-0  0.835
2024 Diez I, Ortiz-Terán L, Ng TSC, Albers MW, Marshall G, Orwig W, Kim CM, Bueichekú E, Montal V, Olofsson J, Vannini P, El Fahkri G, Sperling R, Johnson K, Jacobs HIL, et al. Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging. Nature Communications. 15: 4809. PMID 38844444 DOI: 10.1038/s41467-024-48462-3  0.52
2024 Pahl J, Prokopiou PC, Bueichekú E, Schultz AP, Papp KV, Farrell ME, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer's disease. Alzheimer's Research & Therapy. 16: 119. PMID 38822365 DOI: 10.1186/s13195-024-01485-w  0.772
2024 Lee S, Zide BS, Palm ST, Drew WJ, Sperling RA, Jacobs HIL, Siddiqi SH, Donovan NJ. Specific Association of Worry With Amyloid-β But Not Tau in Cognitively Unimpaired Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 38763835 DOI: 10.1016/j.jagp.2024.04.016  0.565
2024 Schneider C, Prokopiou PC, Papp KV, Engels-Domínguez N, Hsieh S, Juneau TA, Schultz AP, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38676563 DOI: 10.1002/alz.13839  0.743
2024 Bueichekú E, Diez I, Kim CM, Becker JA, Koops EA, Kwong K, Papp KV, Salat DH, Bennett DA, Rentz DM, Sperling RA, Johnson KA, Sepulcre J, Jacobs HIL. Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition. Nature Aging. PMID 38664576 DOI: 10.1038/s43587-024-00626-y  0.836
2024 Beckers E, Riphagen JM, Van Egroo M, Bennett DA, Jacobs HIL. Sparse Asymmetry in Locus Coeruleus Pathology in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 38607758 DOI: 10.3233/JAD-231328  0.52
2024 Van Egroo M, van Someren EJW, Grinberg LT, Bennett DA, Jacobs HIL. Associations of 24-Hour Rest-Activity Rhythm Fragmentation, Cognitive Decline, and Postmortem Locus Coeruleus Hypopigmentation in Alzheimer's Disease. Annals of Neurology. PMID 38407546 DOI: 10.1002/ana.26880  0.693
2024 Zide BS, Donovan NJ, Lee S, Nag S, Bennett DA, Jacobs HIL. Social activity mediates locus coeruleus tangle-related cognition in older adults. Molecular Psychiatry. PMID 38355788 DOI: 10.1038/s41380-024-02467-y  0.523
2023 Hanseeuw BJ, Jacobs HI, Schultz AP, Buckley RF, Farrell ME, Guehl NJ, Becker JA, Properzi M, Sanchez JS, Quiroz YT, Vannini P, Sepulcre J, Yang HS, Chhatwal JP, Gatchel J, et al. Association of pathological and volumetric biomarker changes with cognitive decline in clinically normal adults: Harvard Aging Brain Study. Neurology. PMID 37968130 DOI: 10.1212/WNL.0000000000207962  0.842
2023 Scott MR, Edwards NC, Properzi MJ, Jacobs HI, Price JC, Lois C, Farrell ME, Hanseeuw BJ, Thibault EG, Rentz DM, Johnson KA, Sperling RA, Schultz AP, Buckley RF. Contribution of extracerebral tracer retention and partial volume effects to sex differences in Flortaucipir-PET signal. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231196978. PMID 37728659 DOI: 10.1177/0271678X231196978  0.424
2023 Prokopiou PC, Engels-Domínguez N, Schultz AP, Sepulcre J, Koops EA, Papp KV, Marshall GA, Normandin MD, El Fakhri G, Rentz D, Sperling RA, Johnson KA, Jacobs HIL. Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease. Neurology. PMID 37491329 DOI: 10.1212/WNL.0000000000207646  0.824
2023 Arleo A, Bareš M, Bernard JA, Bogoian HR, Bruchhage MMK, Bryant P, Carlson ES, Chan CCH, Chen LK, Chung CP, Dotson VM, Filip P, Guell X, Habas C, Jacobs HIL, et al. Consensus Paper: Cerebellum and Ageing. Cerebellum (London, England). PMID 37428408 DOI: 10.1007/s12311-023-01577-7  0.334
2023 Dronse J, Ohndorf A, Richter N, Bischof GN, Fassbender R, Behfar Q, Gramespacher H, Dillen K, Jacobs HIL, Kukolja J, Fink GR, Onur OA. Serum cortisol is negatively related to hippocampal volume, brain structure, and memory performance in healthy aging and Alzheimer's disease. Frontiers in Aging Neuroscience. 15: 1154112. PMID 37251803 DOI: 10.3389/fnagi.2023.1154112  0.707
2023 Freeze WM, Van Veluw SJ, Jansen WJ, Bennett DA, Jacobs HIL. Locus coeruleus pathology is associated with cerebral microangiopathy at autopsy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37095709 DOI: 10.1002/alz.13096  0.368
2023 Van Egroo M, Riphagen JM, Ashton NJ, Janelidze S, Sperling RA, Johnson KA, Yang HS, Bennett DA, Blennow K, Hansson O, Zetterberg H, Jacobs HIL. Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau. Molecular Psychiatry. 1-11. PMID 37020050 DOI: 10.1038/s41380-023-02041-y  0.661
2023 Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgàs N, Dutt S, Mather M, Ludwig M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, ... ... Jacobs HIL, et al. Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36642985 DOI: 10.1002/alz.12937  0.73
2023 Koops EA, Jacobs HIL. Untangling white matter fibre changes in Alzheimer's disease and small vessel disease. Brain : a Journal of Neurology. 146: 413-415. PMID 36567494 DOI: 10.1093/brain/awac493  0.77
2022 Engels-Domínguez N, Koops EA, Prokopiou PC, Van Egroo M, Schneider C, Riphagen JM, Singhal T, Jacobs HIL. State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer's disease: Challenges and opportunities. Neuroscience and Biobehavioral Reviews. 144: 104998. PMID 36526031 DOI: 10.1016/j.neubiorev.2022.104998  0.793
2022 Drenthen GS, Backes WH, Freeze WM, Jacobs HIL, Verheggen ICM, van Boxtel MPJ, Hoff EI, Verhey FR, Jansen JFA. Rich-Club Connectivity of the Structural Covariance Network Relates to Memory Processes in Mild Cognitive Impairment and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35871335 DOI: 10.3233/JAD-220175  0.377
2022 Riphagen JM, van Hooren RWE, Kenis G, Verhey FRJ, Jacobs HIL. Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology. Journal of Alzheimer's Disease : Jad. PMID 35662115 DOI: 10.3233/JAD-215353  0.499
2022 Buckley RF, O'Donnell A, McGrath ER, Jacobs HIL, Lois C, Satizabal CL, Ghosh S, Rubinstein ZB, Murabito JM, Sperling RA, Johnson KA, Seshadri S, Beiser AS. Menopause status moderates sex differences in tau burden: a Framingham PET Study. Annals of Neurology. PMID 35471588 DOI: 10.1002/ana.26382  0.491
2022 Farrell ME, Papp KV, Buckley RF, Jacobs HIL, Schultz AP, Properzi MJ, Vannini P, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Association of Emerging β-Amyloid and Tau Pathology With Early Cognitive Changes in Clinically Normal Older Adults. Neurology. PMID 35338074 DOI: 10.1212/WNL.0000000000200137  0.782
2022 Prokopiou PC, Engels-Domínguez N, Papp KV, Scott MR, Schultz AP, Schneider C, Farrell ME, Buckley RF, Quiroz YT, El Fakhri G, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals. Nature Communications. 13: 1571. PMID 35322012 DOI: 10.1038/s41467-022-28986-2  0.819
2022 Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Domínguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz YT. Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35298083 DOI: 10.1002/alz.12656  0.777
2022 Jacobs HIL, O'Donnell A, Satizabal CL, Lois C, Kojis D, Hanseeuw BJ, Thibault E, Sanchez JS, Buckley RF, Yang Q, DeCarli C, Killiany R, Sargurupremraj M, Sperling RA, Johnson KA, et al. Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study. Journal of Alzheimer's Disease : Jad. PMID 35213372 DOI: 10.3233/JAD-215372  0.629
2021 Van Egroo M, van Hooren RWE, Jacobs HIL. Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer's disease plasma biomarkers: a 7T MRI study. Alzheimer's Research & Therapy. 13: 159. PMID 34560904 DOI: 10.1186/s13195-021-00902-8  0.375
2021 Jacobs HIL, Becker JA, Kwong K, Engels-Domínguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d'Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, et al. In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline. Science Translational Medicine. 13: eabj2511. PMID 34550726 DOI: 10.1126/scitranslmed.abj2511  0.829
2021 Fox-Fuller JT, Torrico-Teave H, d'Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzmán-Vélez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, et al. Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: A cross-sectional study. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12233. PMID 34541287 DOI: 10.1002/dad2.12233  0.822
2021 van der Thiel MM, Freeze WM, Verheggen ICM, Wong SM, de Jong JJA, Postma AA, Hoff EI, Gronenschild EHBM, Verhey FR, Jacobs HIL, Ramakers IHGB, Backes WH, Jansen JFA. Associations of increased interstitial fluid with vascular and neurodegenerative abnormalities in a memory clinic sample. Neurobiology of Aging. 106: 257-267. PMID 34320463 DOI: 10.1016/j.neurobiolaging.2021.06.017  0.379
2021 Chen X, Onur Ö, Richter N, Fassbender R, Gramespacher H, Behfar Q, Reutern B, Dillen K, Jacobs H, Kukolja J, Fink GR, Dronse J. Concordance of intrinsic brain connectivity measures is disrupted in Alzheimer's disease. Brain Connectivity. PMID 34269605 DOI: 10.1089/brain.2020.0918  0.361
2021 Jacobs H, Schoemaker D, Torrico-Teave H, Zuluaga Y, Velilla-Jimenez L, Ospina-Villegas C, Lopera F, Arboleda-Velasquez J, Quiroz YT. Specific abnormalities in white matter pathways as interface to small vessels disease and cognition in CADASIL individuals. Brain Connectivity. PMID 33980027 DOI: 10.1089/brain.2020.0980  0.614
2021 Yang F, Chowdhury SR, Jacobs HIL, Sepulcre J, Wedeen VJ, Johnson KA, Dutta J. Longitudinal Predictive Modeling of Tau Progression Along the Structural Connectome. Neuroimage. 118126. PMID 33957234 DOI: 10.1016/j.neuroimage.2021.118126  0.434
2021 Mayblyum DV, Becker JA, Jacobs HIL, Buckley RF, Schultz AP, Sepulcre J, Sanchez JS, Rubinstein ZB, Katz SR, Moody KA, Vannini P, Papp KV, Rentz DM, Price JC, Sperling RA, et al. Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer Disease. Neurology. PMID 33952655 DOI: 10.1212/WNL.0000000000012108  0.734
2021 van Hooren RWE, Verhey FRJ, Ramakers IHGB, Jansen WJ, Jacobs HIL. Elevated norepinephrine metabolism is linked to cortical thickness in the context of Alzheimer's disease pathology. Neurobiology of Aging. 102: 17-22. PMID 33667876 DOI: 10.1016/j.neurobiolaging.2021.01.024  0.567
2021 Riphagen JM, van Egroo M, Jacobs HIL. Elevated Norepinephrine Metabolism Gauges Alzheimer's Disease-Related Pathology and Memory Decline. Journal of Alzheimer's Disease : Jad. 80: 521-526. PMID 33554915 DOI: 10.3233/JAD-201411  0.428
2021 Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, et al. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Science Translational Medicine. 13. PMID 33472953 DOI: 10.1126/scitranslmed.abc0655  0.771
2021 Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, ... ... Jacobs HIL, et al. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimer's Research & Therapy. 13: 27. PMID 33451357 DOI: 10.1186/s13195-020-00765-5  0.764
2021 Pagen LHG, van de Ven VG, Gronenschild EHBM, Priovoulos N, Verhey FRJ, Jacobs HIL. Contributions of Cerebro-Cerebellar Default Mode Connectivity Patterns to Memory Performance in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. 75: 633-647. PMID 32310164 DOI: 10.3233/JAD-191127  0.404
2020 Song TA, Chowdhury SR, Yang F, Jacobs HIL, Sepulcre J, Wedeen VJ, Johnson KA, Dutta J. A physics-informed geometric learning model for pathological tau spread in Alzheimer's disease. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 12267: 418-427. PMID 33263115 DOI: 10.1007/978-3-030-59728-3_41  0.382
2020 Farrell ME, Jiang S, Schultz AP, Properzi MJ, Price JC, Becker JA, Jacobs HIL, Hanseeuw BJ, Rentz DM, Villemagne VL, Papp KV, Mormino EC, Betensky RA, Johnson KA, Sperling RA, et al. Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology. PMID 33199430 DOI: 10.1212/WNL.0000000000011214  0.732
2020 Hampton OL, Buckley RF, Manning LK, Scott MR, Properzi MJ, Peña-Gómez C, Jacobs HIL, Chhatwal JP, Johnson KA, Sperling RA, Schultz AP. Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage. Clinical. 28: 102407. PMID 32942175 DOI: 10.1016/J.Nicl.2020.102407  0.58
2020 Buckley RF, Scott MR, Jacobs HI, Schultz AP, Properzi MJ, Amarglio RE, Hohman TJ, Mayblyum DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA. Sex mediates relationships between regional tau pathology and cognitive decline. Annals of Neurology. PMID 32799367 DOI: 10.1002/Ana.25878  0.544
2020 Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 116991. PMID 32512123 DOI: 10.1016/J.Neuroimage.2020.116991  0.628
2020 Riphagen JM, Schmiedek L, Gronenschild EHBM, Yassa MA, Priovoulos N, Sack AT, Verhey FRJ, Jacobs HIL. Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study. Scientific Reports. 10: 7572. PMID 32371923 DOI: 10.1038/S41598-020-64595-Z  0.491
2020 Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. PMID 32273431 DOI: 10.1212/WNL.0000000000009362  0.76
2020 Biddle KD, Jacobs HIL, d'Oleire Uquillas F, Zide BS, Kirn DR, Properzi MR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Associations of Widowhood and β-Amyloid With Cognitive Decline in Cognitively Unimpaired Older Adults. Jama Network Open. 3: e200121. PMID 32101313 DOI: 10.1001/jamanetworkopen.2020.0121  0.804
2019 Vannini P, Uquillas FD, Jacobs HIL, Sepulcre J, Gatchel J, Amariglio RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults. Neuroimage. Clinical. 24: 102097. PMID 31795044 DOI: 10.1016/J.Nicl.2019.102097  0.72
2019 Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL. Linking APOE-ε4, blood-brain barrier dysfunction, and inflammation to Alzheimer's pathology. Neurobiology of Aging. 85: 96-103. PMID 31733942 DOI: 10.1016/j.neurobiolaging.2019.09.020  0.387
2019 Freeze WM, Jacobs HIL, de Jong JJ, Verheggen ICM, Gronenschild EHBM, Palm WM, Hoff EI, Wardlaw JM, Jansen JFA, Verhey FR, Backes WH. White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed. Neurobiology of Aging. PMID 31718926 DOI: 10.1016/j.neurobiolaging.2019.09.017  0.413
2019 d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P. Functional and Pathological Correlates of Judgments of Learning in Cognitively Unimpaired Older Adults. Cerebral Cortex (New York, N.Y. : 1991). PMID 31696223 DOI: 10.1093/cercor/bhz217  0.812
2019 Duecker F, Mayrhofer HC, Jacobs HIL, Sack AT. No effect of cold pressor test-induced arousal on attentional benefits and costs in an endogenous spatial orienting paradigm. Neuropsychologia. 135: 107250. PMID 31682926 DOI: 10.1016/J.Neuropsychologia.2019.107250  0.419
2019 Wolters AF, van de Weijer SCF, Leentjens AFG, Duits AA, Jacobs HIL, Kuijf ML. "Resting-state fMRI in Parkinson's disease patients with cognitive impairment: A meta-analysis": Answer to Wang and colleagues. Parkinsonism & Related Disorders. 66: 253-254. PMID 31431324 DOI: 10.1016/j.parkreldis.2019.07.014  0.326
2019 Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA. Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD. Neuroimage. Clinical. 24: 101978. PMID 31422337 DOI: 10.1016/j.nicl.2019.101978  0.364
2019 Song TA, Roy Chowdhury S, Yang F, Jacobs H, El Fakhri G, Li Q, Johnson K, Dutta J. GRAPH CONVOLUTIONAL NEURAL NETWORKS FOR ALZHEIMER'S DISEASE CLASSIFICATION. Proceedings. Ieee International Symposium On Biomedical Imaging. 2019: 414-417. PMID 31327984 DOI: 10.1109/ISBI.2019.8759531  0.347
2019 Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, ... ... Jacobs HIL, et al. Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases. Brain : a Journal of Neurology. PMID 31327002 DOI: 10.1093/Brain/Awz193  0.674
2019 Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 31248770 DOI: 10.1016/j.jagp.2019.05.005  0.577
2019 Bischof GN, Jacobs HIL. Subthreshold amyloid and its biological and clinical meaning: Long way ahead. Neurology. PMID 31167933 DOI: 10.1212/Wnl.0000000000007747  0.749
2019 Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, et al. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. Jama Neurology. PMID 31157827 DOI: 10.1001/Jamaneurol.2019.1424  0.85
2019 Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J. A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity. Information Processing in Medical Imaging : Proceedings of the ... Conference. 11492: 384-393. PMID 31156312 DOI: 10.1007/978-3-030-20351-1_29  0.405
2019 Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ. Alzheimer's disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms. Molecular Psychiatry. 26: 897-906. PMID 31138892 DOI: 10.1038/s41380-019-0437-x  0.516
2019 Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging. 78: 178-185. PMID 30947113 DOI: 10.1016/J.Neurobiolaging.2019.02.019  0.567
2019 Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, et al. Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults. Jama Neurology. PMID 30715078 DOI: 10.1001/Jamaneurol.2018.4693  0.738
2018 Wolters AF, van de Weijer SCF, Leentjens AFG, Duits AA, Jacobs HIL, Kuijf ML. Resting-state fMRI in Parkinson's disease patients with cognitive impairment: A meta-analysis. Parkinsonism & Related Disorders. 62: 16-27. PMID 30580907 DOI: 10.1016/j.parkreldis.2018.12.016  0.355
2018 d'Oleire Uquillas F, Jacobs HIL, Biddle KD, Properzi M, Hanseeuw B, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry. 8: 282. PMID 30563962 DOI: 10.1038/s41398-018-0345-x  0.837
2018 Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, ... ... Jacobs H, et al. The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology. PMID 30549303 DOI: 10.1002/Ana.25395  0.836
2018 Jacobs HIL, Buckley RF. Where do white matter alterations dovetail with the cascade model of Alzheimer's disease? Brain : a Journal of Neurology. 141: 2830-2833. PMID 30535117 DOI: 10.1093/brain/awy243  0.355
2018 Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine. PMID 30374196 DOI: 10.1038/S41591-018-0206-4  0.816
2018 Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL. Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes. Journal of Alzheimer's Disease : Jad. PMID 30320590 DOI: 10.3233/Jad-180676  0.646
2018 Mayrhofer HC, Duecker F, van de Ven V, Jacobs HIL, Sack AT. Hemifield-specific Correlations between Cue-related Blood Oxygen Level Dependent Activity in Bilateral Nodes of the Dorsal Attention Network and Attentional Benefits in a Spatial Orienting Paradigm. Journal of Cognitive Neuroscience. 1-14. PMID 30240311 DOI: 10.1162/Jocn_A_01338  0.433
2018 Van Hooren RWE, Riphagen JM, Jacobs HIL. Inter-network connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimer's Research & Therapy. 10: 88. PMID 30153858 DOI: 10.1186/s13195-018-0420-9  0.48
2018 Bos I, Verhey FR, Ramakers IHGB, Jacobs HIL, Soininen H, Freund-Levi Y, Hampel H, Tsolaki M, Wallin ÅK, van Buchem MA, Oleksik A, Verbeek MM, Rikkert MO, van der Flier WM, Scheltens P, et al. Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline. Alzheimer's Research & Therapy. 10: 56. PMID 29925412 DOI: 10.1186/S13195-018-0391-X  0.331
2018 Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A. Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study. Neurobiology of Aging. 69: 167-176. PMID 29908415 DOI: 10.1016/j.neurobiolaging.2018.05.021  0.316
2018 Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, et al. Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29803541 DOI: 10.1016/J.Jalz.2018.04.010  0.759
2018 Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vanini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, et al. PET staging of amyloidosis using striatum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29792874 DOI: 10.1016/J.Jalz.2018.04.011  0.715
2018 Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA. 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. Journal of Alzheimer's Disease : Jad. 62: 1691-1702. PMID 29614677 DOI: 10.3233/Jad-170840  0.41
2018 Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nature Neuroscience. PMID 29403032 DOI: 10.1038/s41593-018-0070-z  0.773
2018 d'Oleire Uquillas F, Jacobs HIL, Hanseeuw B, Marshall GA, Properzi M, Schultz AP, LaPoint MR, Johnson KA, Sperling RA, Vannini P. Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage. Clinical. 17: 388-396. PMID 29159051 DOI: 10.1016/j.nicl.2017.10.034  0.837
2017 Bos I, Verhey FR, Ramakers IHGB, Jacobs HIL, Soininen H, Freund-Levi Y, Hampel H, Tsolaki M, Wallin ÅK, van Buchem MA, Oleksik A, Verbeek MM, Olde Rikkert M, van der Flier WM, Scheltens P, et al. Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline. Alzheimer's Research & Therapy. 9: 101. PMID 29284531 DOI: 10.1186/S13195-017-0328-9  0.476
2017 Jacobs HIL, Hopkins DA, Mayrhofer HC, Bruner E, van Leeuwen FW, Raaijmakers W, Schmahmann JD. The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline. Brain : a Journal of Neurology. PMID 29053771 DOI: 10.1093/brain/awx194  0.454
2017 Dillen KNH, Jacobs HIL, Kukolja J, Richter N, von Reutern B, Onur ÖA, Langen KJ, Fink GR. Functional Disintegration of the Default Mode Network in Prodromal Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28598839 DOI: 10.3233/JAD-161120  0.364
2017 Dekhtyar M, Papp KV, Buckley R, Jacobs HIL, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Neuroimaging Markers Associated with Maintenance of Optimal Memory Performance in Late-Life. Neuropsychologia. PMID 28472627 DOI: 10.1016/j.neuropsychologia.2017.04.037  0.619
2017 Cleutjens FAHM, Ponds RWHM, Spruit MA, Burgmans S, Jacobs HIL, Gronenschild EHBM, Staals J, Franssen FME, Dijkstra JB, Vanfleteren LEGW, Hofman PA, Wouters EFM, Janssen DJA. The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study. Frontiers in Aging Neuroscience. 9: 88. PMID 28424613 DOI: 10.3389/Fnagi.2017.00088  0.305
2016 Freeze WM, Jacobs HI, Gronenschild EH, Jansen JF, Burgmans S, Aalten P, Clerx L, Vos SJ, van Buchem MA, Barkhof F, van der Flier WM, Verbeek MM, Rikkert MO, Backes WH, Verhey FR, et al. White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-β. Journal of Alzheimer's Disease : Jad. PMID 27662299 DOI: 10.3233/Jad-160474  0.49
2016 Dillen KN, Jacobs HI, Kukolja J, von Reutern B, Richter N, Onur ÖA, Dronse J, Langen KJ, Fink GR. Aberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer's disease. Neurobiology of Aging. 44: 114-26. PMID 27318139 DOI: 10.1016/j.neurobiolaging.2016.04.010  0.449
2015 Clerx L, Gronenschild EH, Echavarri C, Verhey F, Aalten P, Jacobs HI. Can FreeSurfer Compete with Manual Volumetric Measurements in Alzheimer's Disease? Current Alzheimer Research. 12: 358-67. PMID 25817249  0.426
2015 Jacobs HI, Riphagen JM, Razat CM, Wiese S, Sack AT. Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiology of Aging. 36: 1860-7. PMID 25805212 DOI: 10.1016/J.Neurobiolaging.2015.02.023  0.505
2015 Jacobs HI, Wiese S, van de Ven V, Gronenschild EH, Verhey FR, Matthews PM. Relevance of parahippocampal-locus coeruleus connectivity to memory in early dementia. Neurobiology of Aging. 36: 618-26. PMID 25433457 DOI: 10.1016/j.neurobiolaging.2014.10.041  0.365
2015 Jacobs HI, Gronenschild EH, Evers EA, Ramakers IH, Hofman PA, Backes WH, Jolles J, Verhey FR, Van Boxtel MP. Visuospatial processing in early Alzheimer's disease: a multimodal neuroimaging study. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 64: 394-406. PMID 22342463 DOI: 10.1016/J.Cortex.2012.01.005  0.604
2014 Lückmann HC, Jacobs HI, Sack AT. The cross-functional role of frontoparietal regions in cognition: internal attention as the overarching mechanism. Progress in Neurobiology. 116: 66-86. PMID 24530293 DOI: 10.1016/J.Pneurobio.2014.02.002  0.522
2014 Jacobs HI, Clerx L, Gronenschild EH, Aalten P, Verhey FR. White matter hyperintensities are positively associated with cortical thickness in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 39: 409-22. PMID 24169238 DOI: 10.3233/JAD-131232  0.396
2013 Jacobs HI, Radua J, Lückmann HC, Sack AT. Meta-analysis of functional network alterations in Alzheimer's disease: toward a network biomarker. Neuroscience and Biobehavioral Reviews. 37: 753-65. PMID 23523750 DOI: 10.1016/J.Neubiorev.2013.03.009  0.568
2013 Bruner E, Jacobs HI. Alzheimer's disease: the downside of a highly evolved parietal lobe? Journal of Alzheimer's Disease : Jad. 35: 227-40. PMID 23435412 DOI: 10.3233/JAD-122299  0.451
2013 Mills JD, Nalpathamkalam T, Jacobs HI, Janitz C, Merico D, Hu P, Janitz M. RNA-Seq analysis of the parietal cortex in Alzheimer's disease reveals alternatively spliced isoforms related to lipid metabolism. Neuroscience Letters. 536: 90-5. PMID 23305720 DOI: 10.1016/j.neulet.2012.12.042  0.353
2013 Jacobs HI, van Boxtel MP, Gronenschild EH, Uylings HB, Jolles J, Verhey FR. Decreased gray matter diffusivity: a potential early Alzheimer's disease biomarker? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 93-7. PMID 22651939 DOI: 10.1016/J.Jalz.2011.11.004  0.543
2013 Jacobs HI, Leritz EC, Williams VJ, Van Boxtel MP, van der Elst W, Jolles J, Verhey FR, McGlinchey RE, Milberg WP, Salat DH. Association between white matter microstructure, executive functions, and processing speed in older adults: the impact of vascular health. Human Brain Mapping. 34: 77-95. PMID 21954054 DOI: 10.1002/Hbm.21412  0.503
2012 Jacobs HI, van Boxtel MP, Gronenschild EH, Williams VJ, Burgmans S, Uylings HB, Jolles J, Verhey FR. Patterns of gray and white matter changes in individuals at risk for Alzheimer's disease. Current Alzheimer Research. 9: 1097-105. PMID 22920268 DOI: 10.2174/156720512803568993  0.616
2012 Jacobs HI, Van Boxtel MP, Jolles J, Verhey FR, Uylings HB. Parietal cortex matters in Alzheimer's disease: an overview of structural, functional and metabolic findings. Neuroscience and Biobehavioral Reviews. 36: 297-309. PMID 21741401 DOI: 10.1016/J.Neubiorev.2011.06.009  0.627
2012 Jacobs HI, Visser PJ, Van Boxtel MP, Frisoni GB, Tsolaki M, Papapostolou P, Nobili F, Wahlund LO, Minthon L, Frölich L, Hampel H, Soininen H, van de Pol L, Scheltens P, Tan FE, et al. Association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent. Neurobiology of Aging. 33: 201.e1-8. PMID 20739101 DOI: 10.1016/J.Neurobiolaging.2010.07.015  0.534
2011 Jacobs HI, Van Boxtel MP, van der Elst W, Burgmans S, Smeets F, Gronenschild EH, Verhey FR, Uylings HB, Jolles J. Increasing the diagnostic accuracy of medial temporal lobe atrophy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 477-90. PMID 21471642 DOI: 10.3233/Jad-2011-102043  0.659
2011 Jacobs HI, Van Boxtel MP, Uylings HB, Gronenschild EH, Verhey FR, Jolles J. Atrophy of the parietal lobe in preclinical dementia. Brain and Cognition. 75: 154-63. PMID 21130554 DOI: 10.1016/J.Bandc.2010.11.003  0.617
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