Bruce L. Kagan

University of California, Los Angeles, Los Angeles, CA 
Channel forming toxins/ Amyloid/Planar lipid bilayers
"Bruce Kagan"
Mean distance: 15.12 (cluster 32)
Cross-listing: Chemistry Tree


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Alan Finkelstein grad student Albert Einstein
R. John Collier grad student 1982-1985 UCLA (Chemistry Tree)


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Meng-chin Lin grad student UCLA
Tajib Mirzabekov post-doc 1992-1996 UCLA
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Jang H, Arce FT, Lee J, et al. (2016) Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels. Methods in Molecular Biology (Clifton, N.J.). 1345: 251-68
Patel N, Ramachandran S, Azimov R, et al. (2015) Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Taupathies. Biochemistry
Lee J, Gillman AL, Jang H, et al. (2014) Role of the fast kinetics of pyroglutamate-modified amyloid-β oligomers in membrane binding and membrane permeability. Biochemistry. 53: 4704-14
Gillman AL, Jang H, Lee J, et al. (2014) Activity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) pores. The Journal of Physical Chemistry. B. 118: 7335-44
Jang H, Arce FT, Ramachandran S, et al. (2014) Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs. Chemical Society Reviews. 43: 6750-64
Jang H, Arce FT, Ramachandran S, et al. (2013) Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment. The Journal of Physical Chemistry. B. 117: 11518-29
Jang H, Connelly L, Arce FT, et al. (2013) Alzheimer's disease: which type of amyloid-preventing drug agents to employ? Physical Chemistry Chemical Physics : Pccp. 15: 8868-77
Jang H, Connelly L, Arce FT, et al. (2013) Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane. Journal of Chemical Theory and Computation. 9: 822-833
Arce FT, Jang H, Connelly L, et al. (2013) Structure-Function Studies of Amyloid Pores in Alzheimer's Disease as a Case Example of Neurodegenerative Diseases Bio-Nanoimaging: Protein Misfolding and Aggregation. 397-408
Kagan BL. (2012) Membrane pores in the pathogenesis of neurodegenerative disease. Progress in Molecular Biology and Translational Science. 107: 295-325
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