Keir C. Neuman, Ph.D.

Princeton University, Princeton, NJ 
biophysics, single molecules, motor proteins, transcription
"Keir Neuman"
Mean distance: 15.3 (cluster 6)


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Steven M. Block grad student 2002 Princeton
 (Single molecule study of RNA polymerase transcription under load.)


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Mate Gyimesi post-doc 2012-2014 UC Davis (Cell Biology Tree)
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Harami GM, Pálinkás J, Seol Y, et al. (2022) The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops. Nature Communications. 13: 654
McKie SJ, Desai P, Seol Y, et al. (2022) Topoisomerase VI is a chirally-selective, preferential DNA decatenase. Elife. 11
McKie SJ, Neuman KC, Maxwell A. (2021) DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2000286
McKie SJ, Maxwell A, Neuman KC. (2020) Mapping DNA Topoisomerase Binding and Cleavage Genome Wide Using Next-Generation Sequencing Techniques. Genes. 11
Seol Y, Dinh YT, Neuman KC. (2020) Domain Rigidity Modulates the Catalytic Activity of E. coli Type IA DNA Topoisomerases Biophysical Journal. 118
Kovacs ZJ, Hubert Á, Baráth V, et al. (2020) Probing and Visualization of the RecQ Helicase-Induced DNA Binding Mode Change of the Bacterial Single-Stranded DNA Binding (SSB) Protein Biophysical Journal. 118
Desai PR, Das S, Neuman KC. (2020) Coarse-Grained Modeling of DNA Plectoneme Formation in the Presence of Base-Pair Mismatches Biophysical Journal. 118
Gibson EG, Oviatt AA, Cacho M, et al. (2019) Bimodal actions of a naphthyridone/aminopiperidine-based antibacterial that targets gyrase and topoisomerase IV. Biochemistry
Seol Y, Harami GM, Kovács M, et al. (2019) Homology sensing via non-linear amplification of sequence dependent pausing by RecQ helicase. Elife. 8
Harami GM, Palinkas J, Seol Y, et al. (2019) Novel Assay Resolves D-Loop Processing Pathways by E. Coli RecQ and Human BLM Helicases Biophysical Journal. 116: 74a
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