Anne C. Hart

Harvard Medical School, Boston, MA, United States 
 Neuroscience Brown University, Providence, RI 
"Anne Hart"
Mean distance: 15.29 (cluster 11)
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Baskoylu SN, Yersak J, O'Hern P, et al. (2018) Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration. Plos Genetics. 14: e1007682
Sorkaç A, DiIorio MA, O'Hern PJ, et al. (2018) LIN-12/Notch Regulates GABA Signaling at the Neuromuscular Junction. G3 (Bethesda, Md.)
O'Hern PJ, do Carmo G Gonçalves I, Brecht J, et al. (2017) Decreased microRNA levels lead to deleterious increases in neuronal M2 muscarinic receptors in Spinal Muscular Atrophy models. Elife. 6
Riessland M, Kaczmarek A, Schneider S, et al. (2017) Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. American Journal of Human Genetics
Sorkaç A, Alcantara IC, Hart AC. (2016) In Vivo Modelling of ATP1A3 G316S-Induced Ataxia in C. elegans Using CRISPR/Cas9-Mediated Homologous Recombination Reveals Dominant Loss of Function Defects. Plos One. 11: e0167963
Dimitriadi M, Derdowski A, Kalloo G, et al. (2016) Decreased function of survival motor neuron protein impairs endocytic pathways. Proceedings of the National Academy of Sciences of the United States of America
Anderson EN, Corkins ME, Li JC, et al. (2016) C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins. Mechanisms of Ageing and Development
Wan H, Schroeder GM, Hart AC, et al. (2015) Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms Acs Medicinal Chemistry Letters. 6: 850-855
Hart AC, Schroeder GM, Wan H, et al. (2015) Structure-based design of selective janus kinase 2 imidazo[4,5- d ]pyrrolo[2,3- b ]pyridine inhibitors Acs Medicinal Chemistry Letters. 6: 845-849
Moroz N, Carmona JJ, Anderson E, et al. (2014) Dietary restriction involves NAD⁺ -dependent mechanisms and a shift toward oxidative metabolism. Aging Cell. 13: 1075-85
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