Christopher J. Holler, Ph.D.

Affiliations: 
2012 Molecular and Cellular Biochemistry University of Kentucky, Lexington, KY 
Area:
Alzheimer\'s disease
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"Christopher Holler"
Mean distance: 19.49 (cluster 28)
 
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Michael Paul Murphy grad student 2012 University of Kentucky
 (The cellular nucleic acid binding protein regulates the Alzheimer's disease beta-secretase protein BACE1.)
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Publications

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Holler CJ, Taylor G, McEachin ZT, et al. (2016) Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Molecular Neurodegeneration. 11: 46
Holler CJ, Davis PR, Beckett TL, et al. (2014) Bridging integrator 1 (BIN1) protein expression increases in the Alzheimer's disease brain and correlates with neurofibrillary tangle pathology. Journal of Alzheimer's Disease : Jad. 42: 1221-7
Deng Q, Holler CJ, Taylor G, et al. (2014) FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7802-13
Holler CJ, Murphy MP. (2013) BACE1: Expression, regulation, and therapeutic potential of the major Alzheimer's disease beta-Secretase Current Enzyme Inhibition. 9: 3-14
Beckett TL, Webb RL, Niedowicz DM, et al. (2012) Postmortem Pittsburgh Compound B (PiB) binding increases with Alzheimer's disease progression. Journal of Alzheimer's Disease : Jad. 32: 127-38
Holler CJ, Webb RL, Laux AL, et al. (2012) BACE2 expression increases in human neurodegenerative disease. The American Journal of Pathology. 180: 337-50
Niedowicz DM, Beckett TL, Holler CJ, et al. (2010) APP(DeltaNL695) expression in murine tissue downregulates CNBP expression. Neuroscience Letters. 482: 57-61
Beckett TL, Niedowicz DM, Studzinski CM, et al. (2010) Effects of nonsteroidal anti-inflammatory drugs on amyloid-beta pathology in mouse skeletal muscle. Neurobiology of Disease. 39: 449-56
Ahmed RR, Holler CJ, Webb RL, et al. (2010) BACE1 and BACE2 enzymatic activities in Alzheimer's disease. Journal of Neurochemistry. 112: 1045-53
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