Roberto Zoncu, Ph.D.

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA 
 2007 Yale University, New Haven, CT 
Area:
How organelles sense nutrients and regulate cellular growth
Google:
"Roberto Zoncu"
Mean distance: 15.5 (cluster 11)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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Pietro De Camilli grad student 2007 Yale
 (Control of endocytosis by membrane phosphoinositides in living cells.)
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Publications

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Davis OB, Shin HR, Lim CY, et al. (2020) NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C. Developmental Cell
Di Malta C, Siciliano D, Calcagni A, et al. (2017) Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth. Science (New York, N.Y.). 356: 1188-1192
Castellano BM, Thelen AM, Moldavski O, et al. (2017) Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex. Science (New York, N.Y.). 355: 1306-1311
Perera RM, Zoncu R. (2016) The Lysosome as a Regulatory Hub. Annual Review of Cell and Developmental Biology
Okosun J, Wolfson RL, Wang J, et al. (2015) Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics
Wheeler DB, Zoncu R, Root DE, et al. (2015) Identification of an oncogenic RAB protein. Science (New York, N.Y.). 350: 211-7
Perera RM, Stoykova S, Nicolay BN, et al. (2015) Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 524: 361-5
Katajisto P, Döhla J, Chaffer CL, et al. (2015) Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science (New York, N.Y.). 348: 340-3
Tooze S, Zoncu R. (2015) Control of cellular homeostasis: organelles take the pilot's seat. Molecular Biology of the Cell. 26: 1009-10
Wang S, Tsun ZY, Wolfson RL, et al. (2015) Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science (New York, N.Y.). 347: 188-94
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