Christopher P. Austin
Affiliations: | National Institutes of Health, Bethesda, MD |
Area:
development of a toolbox of reagents and technologies to translate genome sequence into functional insightsWebsite:
http://www.genome.gov/12512321Google:
"Christopher Austin"Mean distance: 14.92 (cluster 32) | S | N | B | C | P |
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Publications
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Low LA, Mummery C, Berridge BR, et al. (2020) Organs-on-chips: into the next decade. Nature Reviews. Drug Discovery |
Tambuyzer E, Vandendriessche B, Austin CP, et al. (2019) Therapies for rare diseases: therapeutic modalities, progress and challenges ahead. Nature Reviews. Drug Discovery |
Huang R, Zhu H, Shinn P, et al. (2019) The NCATS Pharmaceutical Collection: a 10-year update. Drug Discovery Today |
Huang R, Grishagin I, Wang Y, et al. (2019) The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics. Frontiers in Pharmacology. 10: 445 |
Nilubol N, Boufraqech M, Zhang L, et al. (2018) Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response. Oncotarget. 9: 33030-33042 |
Coussens NP, Sittampalam GS, Guha R, et al. (2018) The Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery. Clinical and Translational Science |
Marshall LJ, Austin CP, Casey W, et al. (2018) Recommendations toward a human pathway-based approach to disease research. Drug Discovery Today |
Huang R, Xia M, Sakamuru S, et al. (2018) Expanding biological space coverage enhances the prediction of drug adverse effects in human using in vitro activity profiles. Scientific Reports. 8: 3783 |
Wagner JA, Dahlem AM, Hudson LD, et al. (2017) Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development. Clinical and Translational Science |
Dai S, Dulcey AE, Hu X, et al. (2017) Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 0 |