Julius Axelrod, PhD
Affiliations: | National Institute of Mental Health, Bethesda, MD, United States |
Area:
NeurotransmittersWebsite:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1970/axelrod-bio.htmlGoogle:
"Julius Axelrod"Bio:
(1912 - 2004)
http://www.nasonline.org/member-directory/deceased-members/58106.html
http://www.nap.edu/openbook.php?record_id=11522&page=74
http://profiles.nlm.nih.gov/ps/retrieve/Collection/CID/HH
http://en.wikipedia.org/wiki/Julius_Axelrod
The Nobel Prize in Physiology or Medicine 1970 was awarded jointly to Sir Bernard Katz, Ulf von Euler and Julius Axelrod "for their discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation".
Mean distance: 12.17 (cluster 6) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Bernard Beryl Brodie | research assistant | 1946-1949 | Goldwater Memorial Hospital | |
| H. George Mandel | grad student | 1954-1955 | George Washington University (Chemistry Tree) | |
| (The Fate of Phenylisopropylamines) | ||||
Children
Sign in to add traineeCollaborators
Sign in to add collaborator| John W. Daly | collaborator | NIH | |
| Robert Y. Moore | collaborator | University of Pittsburgh |
BETA: Related publications
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Publications
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| AXELROD J, INSCOE JK, SENOH S, et al. (2000) O-methylation, the principal pathway for the metabolism of epinephrine and norepinephrine in the rat. Biochimica Et Biophysica Acta. 27: 210-1 |
| HERTTING G, AXELROD J, PATRICK RW. (1998) Actions of bretylium and guanethidine on the uptake and release of [3H]-noradrenaline. British Journal of Pharmacology and Chemotherapy. 18: 161-6 |
| DALY J, AXELROD J, WITKOP B. (1998) Methylation and demethylation in relation to the in vitro metabolism of mescaline. Annals of the New York Academy of Sciences. 96: 37-43 |
| AXELROD J, HERTTING G, POTTER L. (1998) Effect of drugs on the uptake and release of 3H-norepinephrine in the rat heart. Nature. 194: 297 |
| Axelrod J, Felder CC. (1998) Cannabinoid receptors and their endogenous agonist, anandamide. Neurochemical Research. 23: 575-81 |
| DALY J, INSCOE JK, AXELROD J. (1996) THE FORMATION OF O-METHYLATED CATECHOLS BY MICROSOMAL HYDROXYLATION OF PHENOLS AND SUBSEQUENT ENZYMATIC CATECHOL O-METHYLATION. SUBSTRATE SPECIFICITY. Journal of Medicinal Chemistry. 8: 153-7 |
| Felder CC, Nielsen A, Briley EM, et al. (1996) Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. Febs Letters. 393: 231-5 |
| Devane WA, Axelrod J. (1994) Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. Proceedings of the National Academy of Sciences of the United States of America. 91: 6698-701 |
| Briley EM, Lolait SJ, Axelrod J, et al. (1994) The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels. Neuropeptides. 27: 63-74 |
| Felder CC, Briley EM, Axelrod J, et al. (1993) Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60 |