David Bredt

Affiliations: 
Eli Lilly and Co., Basingstoke, England, United Kingdom 
Area:
Neurotransmitters
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"David Bredt"
Mean distance: 13.16 (cluster 11)
 
SNBCP

Children

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Houhui Hugh Xia grad student 1994-1997 UCSF
Aaron W. McGee grad student 1995-2001 UCSF
Susumu Tomita post-doc UCSF
Guillermo A. Yudowski post-doc UCSF
Bonnie L. Firestein post-doc 1995-2000 UCSF
Alaa El-Din El-Husseini post-doc 1998-2001 UCSF
Dane M. Chetkovich post-doc 1998-2002 UCSF
Olav Olsen post-doc 2001-2007 UCSF
Martin B. Gill post-doc 2009-2011 Eli Lilly and Co.
Hong Yu research scientist 2004- Eli Lilly & Co
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Publications

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Matta JA, Gu S, Davini WB, et al. (2021) Nicotinic acetylcholine receptor redux: Discovery of accessories opens therapeutic vistas. Science (New York, N.Y.). 373
Rosenbaum MI, Clemmensen LS, Bredt DS, et al. (2020) Targeting receptor complexes: a new dimension in drug discovery. Nature Reviews. Drug Discovery
Knowland D, Gu S, Eckert WA, et al. (2020) Functional α6β4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties. The Journal of Clinical Investigation
Gu S, Knowland D, Matta JA, et al. (2020) Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products. Proceedings of the National Academy of Sciences of the United States of America
Dhara M, Matta JA, Lei M, et al. (2020) Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. Nature Communications. 11: 2799
Dawe GB, Yu H, Gu S, et al. (2019) α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins. Nature Communications. 10: 2746
Knopp KL, Simmons RMA, Guo W, et al. (2019) Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics
Gu S, Matta JA, Davini WB, et al. (2019) α6-Containing Nicotinic Acetylcholine Receptor Reconstitution Involves Mechanistically Distinct Accessory Components. Cell Reports. 26: 866-874.e3
Maher MP, Matta JA, Gu S, et al. (2017) Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins. Neuron. 96: 989-1001
Matta JA, Gu S, Davini WB, et al. (2017) NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain. Cell Reports. 19: 688-696
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