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David Bredt

Affiliations: 
Eli Lilly and Co., Basingstoke, England, United Kingdom 
Area:
Neurotransmitters
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"David Bredt"
Mean distance: 13.16 (cluster 11)
 		SNBCP
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Parents

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Solomon H. Snyder grad student Johns Hopkins

Children

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Houhui Hugh Xia grad student 1994-1997 UCSF
Aaron W. McGee grad student 1995-2001 UCSF
Susumu Tomita post-doc UCSF
Guillermo A. Yudowski post-doc UCSF
Bonnie L. Firestein post-doc 1995-2000 UCSF
Alaa El-Din El-Husseini post-doc 1998-2001 UCSF
Dane M. Chetkovich post-doc 1998-2002 UCSF
Olav Olsen post-doc 2001-2007 UCSF
Martin B. Gill post-doc 2009-2011 Eli Lilly and Co.
Hong Yu research scientist 2004- Eli Lilly & Co

Collaborators

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Roger A. Nicoll collaborator UCSF
BETA: Related publications

Publications

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Kweon HJ, Gu S, Witham E, et al. (2020) NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Reports. 32: 108025
Dhara M, Matta JA, Lei M, et al. (2020) Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. Nature Communications. 11: 2799
Dawe GB, Yu H, Gu S, et al. (2019) α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins. Nature Communications. 10: 2746
Knopp KL, Simmons RMA, Guo W, et al. (2019) Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics
Gu S, Matta JA, Davini WB, et al. (2019) α6-Containing Nicotinic Acetylcholine Receptor Reconstitution Involves Mechanistically Distinct Accessory Components. Cell Reports. 26: 866-874.e3
Maher MP, Matta JA, Gu S, et al. (2017) Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins. Neuron. 96: 989-1001
Kato AS, Burris KD, Gardinier KM, et al. (2016) Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine
Gardinier KM, Gernert DL, Porter WJ, et al. (2016) The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry
Erlenhardt N, Yu H, Abiraman K, et al. (2016) Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Reports
Yudowski GA, Olsen O, Adesnik H, et al. (2013) Acute inactivation of PSD-95 destabilizes AMPA receptors at hippocampal synapses. Plos One. 8: e53965
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